The network for 'generation of neurons' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

generation of neurons

The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.

NameDescriptionProbabilityFunc Analog Organism
pax2apaired box gene 2a0.999
gdf6agrowth differentiation factor 6a0.999
gli1GLI-Kruppel family member 10.997
ndr2nodal-related 20.997
otx2orthodenticle homolog 20.996
lhx2bLIM homeobox 2b0.995
per3period homolog 3 (Drosophila)0.995
gli2aGLI-Kruppel family member GLI2a0.994
notch1anotch homolog 1a0.992
ascl1aachaete-scute complex-like 1a (Drosophila)0.992
neurodneurogenic differentiation0.991
shhasonic hedgehog a0.991
eng2aengrailed 2a0.989
pitx3paired-like homeodomain transcription factor 30.987
otpaorthopedia homolog a0.986
ptf1apancreas specific transcription factor, 1a0.986
nsfaN-ethylmaleimide-sensitive factor a0.985
fezf2FEZ family zinc finger 20.985
atoh1aatonal homolog 1a0.980
restRE1-silencing transcription factor0.979
rx3retinal homeobox gene 30.977
robo2roundabout homolog 20.976
hhiphedgehog interacting protein0.975
lamc1laminin, gamma 10.971
crb2acrumbs homolog 2a0.971
dnmt4DNA (cytosine-5-)-methyltransferase 40.970
six3asine oculis homeobox homolog 3a0.968
shhbsonic hedgehog b0.966
pitx2paired-like homeodomain transcription factor 20.964
otx5orthodenticle homolog 50.962
pax6bpaired box gene 6b0.962
flhfloating head0.961
six3bsine oculis homeobox homolog 3b0.957
hmx3homeo box (H6 family) 30.956
otpborthopedia homolog b0.956
slc17a6bsolute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b0.955
jag1bjagged 1b0.955
foxp2forkhead box P20.955
ndrg4N-myc downstream regulated gene 40.955
osr1odd-skipped related 1 (Drosophila)0.955
ptch2patched 20.952
sox2SRY-box containing gene 20.951
sema3aasemaphorin 3aa0.951
atoh7atonal homolog 70.947
muskmuscle, skeletal, receptor tyrosine kinase0.947
rx2retinal homeobox gene 20.946
prkciprotein kinase C, iota0.946
foxn4forkhead box N40.942
s1pr2sphingosine-1-phosphate receptor 20.941
wnt4awingless-type MMTV integration site family, member 4a0.940
gbx2gastrulation brain homeo box 20.940
tp53tumor protein p530.939
jag2jagged 20.938
rargaretinoic acid receptor gamma a0.938
myod1myogenic differentiation 10.937
rad21RAD21 homolog (S. pombe)0.934
olig2oligodendrocyte lineage transcription factor 20.933
chatcholine acetyltransferase0.932
fn1fibronectin 10.932
nrp2bneuropilin 2b0.931
nkx2.2aNK2 transcription factor related 2a0.930
cntn2contactin 20.927
fgf3fibroblast growth factor 30.923
tuba1tubulin, alpha 10.923
tcf7transcription factor 7 (T-cell specific, HMG-box)0.922
irx4biroquois homeobox protein 4b0.921
stmn2bstathmin-like 2b0.921
myhz2myosin, heavy polypeptide 2, fast muscle specific0.921
slc1a2bsolute carrier family 1 (glial high affinity glutamate transporter), member 2b0.919
dlx5adistal-less homeobox gene 5a0.918
dpysl3dihydropyrimidinase-like 30.917
thtyrosine hydroxylase0.916
foxi1forkhead box I10.915
aldh1a2aldehyde dehydrogenase 1 family, member A20.914
otx1aorthodenticle homolog 1a0.914
nrp1aneuropilin 1a0.914
cdh2cadherin 2, neuronal0.913
egr2bearly growth response 2b0.911
dlx4bdistal-less homeobox gene 4b0.910
foxg1aforkhead box G1a0.909
kbpkif1-binding protein0.909
her15.1hairy and enhancer of split-related 15.10.906
dlx2adistal-less homeobox gene 2a0.903
fstl1bfollistatin-like 1b0.902
igf1rainsulin-like growth factor 1a receptor0.900
ift88intraflagellar transport 88 homolog0.898
mpp5amembrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)0.895
hnf1baHNF1 homeobox Ba0.890
wnt11wingless-type MMTV integration site family, member 110.890
alcambactivated leukocyte cell adhesion molecule b0.889
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.889
wnt5bwingless-type MMTV integration site family, member 5b0.889
lhx1aLIM homeobox 1a0.889
mtpmicrosomal triglyceride transfer protein0.885
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
egl-18Protein EGL-180.998
unc-9Protein UNC-90.934
vab-3Protein VAB-30.919
pha-4Protein PHA-40.911
unc-52Protein UNC-520.904
nhr-67Protein NHR-670.880
ceh-20Protein CEH-200.857
pry-1Protein PRY-10.833
sax-3Protein SAX-30.806
sem-5Protein SEM-50.743
bar-1Protein BAR-10.724
daf-11Protein DAF-110.711
cfim-2Protein CFIM-20.708
unc-73Protein UNC-730.667
let-60Protein LET-600.650
ain-1Protein AIN-10.635
cye-1Protein CYE-10.635
aap-1Protein AAP-10.634
syg-1Protein SYG-10.632
unc-42Protein UNC-420.632
npp-4Protein NPP-40.631
egl-46Protein EGL-460.628
T27A3.1Protein T27A3.10.626
spc-1Protein SPC-10.625
ten-1Protein TEN-10.615
mig-2Protein MIG-20.595
egl-44Protein EGL-440.571
sli-1Protein SLI-10.570
osm-3Protein OSM-30.568
ect-2Protein ECT-20.561
tax-4Protein TAX-40.560
goa-1Protein GOA-10.549
sur-6Protein SUR-60.503
egl-15Protein EGL-150.501
nhr-34Protein NHR-340.497
vab-10Protein VAB-100.486
pxf-1Protein PXF-10.477
hbl-1Protein HBL-10.475
inx-3Protein INX-30.473
unc-62Protein UNC-620.473
smp-1Protein SMP-10.470
egl-36Protein EGL-360.461
eor-1Protein EOR-10.459
C11E4.6Protein C11E4.60.448
hlh-1Protein HLH-10.444
sorb-1Protein SORB-10.436
F33H2.3Protein F33H2.30.432
unc-104Protein UNC-1040.430
hlh-2Protein HLH-20.423
pkg-1Protein PKG-10.417
egl-5Protein EGL-50.409
adr-1Protein ADR-10.407
clk-2Protein CLK-20.405
scc-3Protein SCC-30.400
osm-6Protein OSM-60.399
sma-6Protein SMA-60.398
clh-5Protein CLH-50.398
ifg-1Protein IFG-10.395
fln-2Protein FLN-20.390
egl-27Protein EGL-270.385
pdfr-1Protein PDFR-10.377
daf-12Protein DAF-120.372
tbc-3Protein TBC-30.368
flt-1Protein FLT-10.367
K10D6.4Protein K10D6.40.367
wrm-1Protein WRM-10.362
pat-3Protein PAT-30.362
sdz-28Protein SDZ-280.362
set-1Protein SET-10.359
lat-1Protein LAT-10.355
cam-1Protein CAM-10.354
elt-6Protein ELT-60.352
unc-70Protein UNC-700.347
ldb-1Protein LDB-10.344
T23F11.1Protein T23F11.10.343
CELE_F54D5.5Protein F54D5.50.339
tag-260Protein TAG-2600.338
lin-29Protein LIN-290.335
sel-12Protein SEL-120.335
mec-4Protein MEC-40.331
enu-3Protein ENU-30.319
eya-1Protein EYA-10.316
fcp-1Protein FCP-10.316
egl-13Protein EGL-130.316
unc-27Protein UNC-270.314
T28F4.1Protein T28F4.10.313
lin-12Protein LIN-120.312
hda-3Protein HDA-30.312
srgp-1Protein SRGP-10.306
lam-2Protein LAM-20.305
F09A5.4Protein F09A5.40.301
ceh-27Protein CEH-270.299
zyg-9Protein ZYG-90.299
apb-1Protein APB-10.297
pop-1Protein POP-10.295
ida-1Protein IDA-10.294
mec-6Protein MEC-60.293
glp-1Protein GLP-10.293
T07A9.10Protein T07A9.100.291
unc-115Protein UNC-1150.285
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
EGFRepidermal growth factor receptor1.000
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)1.000
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide1.000
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide1.000
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.999
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.998
TP53tumor protein p530.998
FYNFYN oncogene related to SRC, FGR, YES0.998
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.998
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.997
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.995
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.993
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.988
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.987
FLNAfilamin A, alpha0.982
CREBBPCREB binding protein0.979
GRB2growth factor receptor-bound protein 20.979
QKIquaking homolog, KH domain RNA binding (mouse)0.978
MAPTmicrotubule-associated protein tau0.977
JUNjun proto-oncogene0.969
NCOA1nuclear receptor coactivator 10.957
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.942
RB1retinoblastoma 10.930
ARandrogen receptor0.928
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.924
FN1fibronectin 10.915
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.911
HDAC1histone deacetylase 10.909
SMAD2SMAD family member 20.901
AKT1v-akt murine thymoma viral oncogene homolog 10.880
GSK3Bglycogen synthase kinase 3 beta0.857
ATXN1ataxin 10.855
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.851
SP1Sp1 transcription factor0.840
NCOR1nuclear receptor corepressor 10.824
DLG4discs, large homolog 4 (Drosophila)0.813
SPTBN1spectrin, beta, non-erythrocytic 10.810
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.795
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.794
ACTBactin, beta0.783
SIN3ASIN3 homolog A, transcription regulator (yeast)0.776
EP300E1A binding protein p3000.770
TAL1T-cell acute lymphocytic leukemia 10.767
SMN1survival of motor neuron 1, telomeric0.752
PLCG1phospholipase C, gamma 10.751
LCKlymphocyte-specific protein tyrosine kinase0.746
FGFR1fibroblast growth factor receptor 10.739
BMI1BMI1 polycomb ring finger oncogene0.733
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit0.721
SMAD4SMAD family member 40.716
NTRK3neurotrophic tyrosine kinase, receptor, type 30.712
PCGF2polycomb group ring finger 20.709
FHL2four and a half LIM domains 20.699
IQGAP1IQ motif containing GTPase activating protein 10.689
ITSN1intersectin 1 (SH3 domain protein)0.686
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.685
ATN1atrophin 10.682
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.676
APCadenomatous polyposis coli0.673
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 50.672
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.665
METmet proto-oncogene (hepatocyte growth factor receptor)0.663
PRKCAprotein kinase C, alpha0.660
MAP2K1mitogen-activated protein kinase kinase 10.656
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.656
BCAR1breast cancer anti-estrogen resistance 10.655
TCF4transcription factor 40.650
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.650
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.647
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.646
MMP14matrix metallopeptidase 14 (membrane-inserted)0.645
HSPA1Bheat shock 70kDa protein 1B0.642
EEDembryonic ectoderm development0.641
CDK2cyclin-dependent kinase 20.639
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.637
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.637
MEOX2mesenchyme homeobox 20.634
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.630
MYOD1myogenic differentiation 10.624
IGF1Rinsulin-like growth factor 1 receptor0.623
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.615
RUNX1runt-related transcription factor 10.613
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.612
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.596
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.595
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.591
MAPK8mitogen-activated protein kinase 80.582
STK4serine/threonine kinase 40.579
WDYHV1WDYHV motif containing 10.579
USP11ubiquitin specific peptidase 110.578
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.574
DRD2dopamine receptor D20.573
RANBP9RAN binding protein 90.572
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.572
JAG2jagged 20.567
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.567
MARK2MAP/microtubule affinity-regulating kinase 20.556
TP73tumor protein p730.554
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism