Saccharomyces cerevisiae

84 known processes

RFA1 (YAR007C)

Rfa1p

(Aliases: BUF2,RPA1,FUN3)

RFA1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 236 1.000
cellular response to dna damage stimulus GO:0006974 287 0.998
double strand break repair GO:0006302 105 0.983
dna unwinding involved in dna replication GO:0006268 13 0.981
meiotic nuclear division GO:0007126 163 0.980
meiosis i GO:0007127 92 0.977
double strand break repair via homologous recombination GO:0000724 54 0.967
telomere organization GO:0032200 75 0.957
organelle fission GO:0048285 272 0.953
telomere maintenance GO:0000723 74 0.944
telomere maintenance via recombination GO:0000722 32 0.901
meiotic cell cycle GO:0051321 272 0.880
dna replication GO:0006260 147 0.875
meiotic cell cycle process GO:1903046 229 0.859
telomere maintenance via telomerase GO:0007004 21 0.854
dna dependent dna replication GO:0006261 115 0.842
nucleotide excision repair GO:0006289 50 0.825
dna strand elongation GO:0022616 29 0.814
dna recombination GO:0006310 172 0.799
reciprocal dna recombination GO:0035825 54 0.793
recombinational repair GO:0000725 64 0.787
dna strand elongation involved in dna replication GO:0006271 26 0.744
regulation of organelle organization GO:0033043 243 0.721
dna topological change GO:0006265 10 0.677
telomere maintenance via telomere lengthening GO:0010833 22 0.674
macromolecule catabolic process GO:0009057 383 0.673
heteroduplex formation GO:0030491 9 0.633
rna dependent dna replication GO:0006278 25 0.625
nuclear division GO:0000280 263 0.622
aging GO:0007568 71 0.591
lagging strand elongation GO:0006273 10 0.585
anatomical structure homeostasis GO:0060249 74 0.522
dna geometric change GO:0032392 43 0.467
dna conformation change GO:0071103 98 0.421
cell aging GO:0007569 70 0.409
reciprocal meiotic recombination GO:0007131 54 0.406
homeostatic process GO:0042592 227 0.389
protein dna complex assembly GO:0065004 105 0.380
protein modification by small protein conjugation GO:0032446 144 0.335
protein complex assembly GO:0006461 302 0.328
aromatic compound catabolic process GO:0019439 491 0.317
single organism developmental process GO:0044767 258 0.237
Zebrafish Mouse Worm
cellular nitrogen compound catabolic process GO:0044270 494 0.229
microtubule based process GO:0007017 117 0.218
chromosome segregation GO:0007059 159 0.217
cytoskeleton organization GO:0007010 230 0.211
regulation of biological quality GO:0065008 391 0.187
regulation of cell cycle phase transition GO:1901987 70 0.185
heterocycle catabolic process GO:0046700 494 0.177
nucleobase containing compound catabolic process GO:0034655 479 0.173
dna duplex unwinding GO:0032508 42 0.164
regulation of protein metabolic process GO:0051246 237 0.162
regulation of cell cycle g2 m phase transition GO:1902749 8 0.158
regulation of mitotic cell cycle phase transition GO:1901990 68 0.154
protein ubiquitination GO:0016567 118 0.139
developmental process GO:0032502 261 0.135
Zebrafish Mouse Worm
regulation of dna repair GO:0006282 14 0.131
dna catabolic process GO:0006308 42 0.129
replicative cell aging GO:0001302 46 0.128
dna damage checkpoint GO:0000077 29 0.128
mitotic sister chromatid segregation GO:0000070 85 0.123
regulation of dna recombination GO:0000018 24 0.120
regulation of cellular protein metabolic process GO:0032268 232 0.120
negative regulation of cell cycle phase transition GO:1901988 59 0.111
sister chromatid segregation GO:0000819 93 0.104
regulation of dna templated transcription initiation GO:2000142 19 0.101
base excision repair GO:0006284 14 0.098
Human
cellular macromolecule catabolic process GO:0044265 363 0.098
regulation of nuclear division GO:0051783 103 0.095
non recombinational repair GO:0000726 33 0.091
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.090
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.089
regulation of cell division GO:0051302 113 0.088
dna double strand break processing GO:0000729 8 0.086
regulation of cellular component organization GO:0051128 334 0.086
regulation of cell cycle GO:0051726 195 0.081
multi organism process GO:0051704 233 0.079
response to organic cyclic compound GO:0014070 1 0.079
protein complex biogenesis GO:0070271 314 0.078
mitotic nuclear division GO:0007067 131 0.077
chromosome condensation GO:0030261 19 0.075
regulation of response to dna damage stimulus GO:2001020 17 0.074
positive regulation of signal transduction GO:0009967 20 0.073
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.073
organophosphate ester transport GO:0015748 45 0.072
regulation of chromosome organization GO:0033044 66 0.067
regulation of signaling GO:0023051 119 0.067
cell division GO:0051301 205 0.067
rna catabolic process GO:0006401 118 0.066
establishment of protein localization GO:0045184 367 0.065
regulation of protein catabolic process GO:0042176 40 0.061
reproduction of a single celled organism GO:0032505 191 0.060
cellular protein complex assembly GO:0043623 209 0.058
protein polymerization GO:0051258 51 0.058
single organism catabolic process GO:0044712 619 0.057
negative regulation of cell cycle GO:0045786 91 0.057
protein dna complex subunit organization GO:0071824 153 0.057
nucleoside triphosphate metabolic process GO:0009141 364 0.055
mating type switching GO:0007533 28 0.054
negative regulation of cell cycle process GO:0010948 86 0.054
meiotic mismatch repair GO:0000710 9 0.052
nucleobase containing compound transport GO:0015931 124 0.052
macromolecule methylation GO:0043414 85 0.049
ribonucleoside metabolic process GO:0009119 389 0.049
transition metal ion homeostasis GO:0055076 59 0.049
positive regulation of rna biosynthetic process GO:1902680 286 0.049
regulation of protein complex assembly GO:0043254 77 0.049
positive regulation of protein complex assembly GO:0031334 39 0.048
microtubule cytoskeleton organization GO:0000226 109 0.048
regulation of response to stimulus GO:0048583 157 0.044
negative regulation of organelle organization GO:0010639 103 0.044
reproductive process GO:0022414 248 0.043
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.043
meiotic dna double strand break processing GO:0000706 5 0.042
endomembrane system organization GO:0010256 74 0.041
purine ribonucleotide catabolic process GO:0009154 327 0.041
chromosome separation GO:0051304 33 0.041
mitotic dna integrity checkpoint GO:0044774 18 0.040
negative regulation of proteasomal protein catabolic process GO:1901799 25 0.039
negative regulation of protein catabolic process GO:0042177 27 0.038
mitotic cell cycle process GO:1903047 294 0.038
dna catabolic process exonucleolytic GO:0000738 19 0.037
nucleocytoplasmic transport GO:0006913 163 0.037
chromatin organization GO:0006325 242 0.036
organic cyclic compound catabolic process GO:1901361 499 0.036
meiotic chromosome segregation GO:0045132 31 0.035
dna integrity checkpoint GO:0031570 41 0.034
negative regulation of protein processing GO:0010955 33 0.034
protein transport GO:0015031 345 0.034
modification dependent macromolecule catabolic process GO:0043632 203 0.034
endosomal transport GO:0016197 86 0.034
regulation of dna metabolic process GO:0051052 100 0.034
regulation of signal transduction GO:0009966 114 0.034
positive regulation of cellular biosynthetic process GO:0031328 336 0.033
double strand break repair via break induced replication GO:0000727 25 0.033
ribose phosphate metabolic process GO:0019693 384 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.032
cellular protein catabolic process GO:0044257 213 0.031
organelle assembly GO:0070925 118 0.030
protein modification by small protein conjugation or removal GO:0070647 172 0.030
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.029
double strand break repair via single strand annealing GO:0045002 7 0.029
establishment of organelle localization GO:0051656 96 0.029
regulation of cell cycle checkpoint GO:1901976 6 0.028
cellular component disassembly GO:0022411 86 0.028
regulation of meiosis GO:0040020 42 0.028
positive regulation of nucleic acid templated transcription GO:1903508 286 0.027
mitotic cell cycle phase transition GO:0044772 141 0.027
negative regulation of cell division GO:0051782 66 0.026
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 13 0.026
cellular response to abiotic stimulus GO:0071214 62 0.025
ion transport GO:0006811 274 0.025
response to chemical GO:0042221 390 0.025
spindle organization GO:0007051 37 0.024
regulation of mitotic metaphase anaphase transition GO:0030071 27 0.024
cell communication GO:0007154 345 0.023
sexual reproduction GO:0019953 216 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.023
mitotic cell cycle GO:0000278 306 0.023
atp metabolic process GO:0046034 251 0.023
regulation of proteolysis GO:0030162 44 0.023
nucleus organization GO:0006997 62 0.022
protein processing GO:0016485 64 0.022
regulation of cell cycle process GO:0010564 150 0.022
methylation GO:0032259 101 0.021
sexual sporulation GO:0034293 113 0.021
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 11 0.021
negative regulation of cell cycle g2 m phase transition GO:1902750 5 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.020
nuclear transport GO:0051169 165 0.020
purine ribonucleoside catabolic process GO:0046130 330 0.020
negative regulation of mitotic metaphase anaphase transition GO:0045841 23 0.020
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.020
regulation of protein processing GO:0070613 34 0.019
mitotic sister chromatid separation GO:0051306 26 0.019
dna biosynthetic process GO:0071897 33 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.019
dna templated transcriptional preinitiation complex assembly GO:0070897 51 0.019
chromatin assembly or disassembly GO:0006333 60 0.019
purine ribonucleotide metabolic process GO:0009150 372 0.018
postreplication repair GO:0006301 24 0.018
dna templated transcription initiation GO:0006352 71 0.018
anatomical structure morphogenesis GO:0009653 160 0.018
organophosphate biosynthetic process GO:0090407 182 0.017
positive regulation of cellular component biogenesis GO:0044089 45 0.017
proteolysis GO:0006508 268 0.017
regulation of dna dependent dna replication GO:0090329 37 0.017
cellular developmental process GO:0048869 191 0.017
nucleoside monophosphate metabolic process GO:0009123 267 0.017
protein dna complex disassembly GO:0032986 20 0.017
dna replication okazaki fragment processing GO:0033567 7 0.017
single organism reproductive process GO:0044702 159 0.017
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 24 0.017
cell morphogenesis GO:0000902 30 0.016
nucleoside phosphate catabolic process GO:1901292 331 0.016
mitotic cell cycle checkpoint GO:0007093 56 0.016
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.016
macromolecular complex disassembly GO:0032984 80 0.016
microtubule polymerization GO:0046785 30 0.016
intracellular protein transport GO:0006886 319 0.016
positive regulation of dna templated transcription initiation GO:2000144 13 0.016
carboxylic acid metabolic process GO:0019752 338 0.016
negative regulation of chromosome organization GO:2001251 39 0.016
cell budding GO:0007114 48 0.015
organelle localization GO:0051640 128 0.015
negative regulation of nuclear division GO:0051784 62 0.015
response to uv GO:0009411 4 0.015
negative regulation of chromosome segregation GO:0051985 25 0.015
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.015
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 19 0.015
mitochondrion inheritance GO:0000001 21 0.015
positive regulation of cytoskeleton organization GO:0051495 39 0.014
gene conversion at mating type locus GO:0007534 11 0.014
response to endogenous stimulus GO:0009719 26 0.014
phosphorylation GO:0016310 291 0.013
nucleoside triphosphate catabolic process GO:0009143 329 0.013
transposition GO:0032196 20 0.013
proteasomal protein catabolic process GO:0010498 141 0.013
amino sugar metabolic process GO:0006040 20 0.013
regulation of metaphase anaphase transition of cell cycle GO:1902099 27 0.013
covalent chromatin modification GO:0016569 119 0.013
ribonucleoside monophosphate metabolic process GO:0009161 265 0.013
regulation of mitotic cell cycle GO:0007346 107 0.013
establishment or maintenance of cell polarity GO:0007163 96 0.013
positive regulation of cell communication GO:0010647 28 0.012
histone modification GO:0016570 119 0.012
cellular component morphogenesis GO:0032989 97 0.012
spindle assembly GO:0051225 9 0.012
carbohydrate derivative metabolic process GO:1901135 549 0.012
regulation of mitosis GO:0007088 65 0.012
peptidyl amino acid modification GO:0018193 116 0.012
double strand break repair via nonhomologous end joining GO:0006303 27 0.012
chromatin modification GO:0016568 200 0.012
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 23 0.012
negative regulation of mitotic sister chromatid separation GO:2000816 23 0.012
positive regulation of macromolecule metabolic process GO:0010604 394 0.012
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 35 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
cellular amine metabolic process GO:0044106 51 0.012
transposition rna mediated GO:0032197 17 0.011
mitotic spindle assembly checkpoint GO:0007094 23 0.011
cellular transition metal ion homeostasis GO:0046916 59 0.011
mitotic recombination GO:0006312 55 0.011
regulation of transposition rna mediated GO:0010525 15 0.011
response to abiotic stimulus GO:0009628 159 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.011
metaphase anaphase transition of cell cycle GO:0044784 28 0.011
multi organism reproductive process GO:0044703 216 0.011
negative regulation of dna recombination GO:0045910 13 0.011
protein phosphorylation GO:0006468 197 0.011
establishment of sister chromatid cohesion GO:0034085 17 0.011
negative regulation of meiotic cell cycle GO:0051447 24 0.011
protein localization to nucleus GO:0034504 74 0.011
reproductive process in single celled organism GO:0022413 145 0.011
negative regulation of mitosis GO:0045839 39 0.010
cytogamy GO:0000755 10 0.010
positive regulation of biosynthetic process GO:0009891 336 0.010
mitotic sister chromatid cohesion GO:0007064 38 0.010
nucleosome assembly GO:0006334 16 0.010
positive regulation of response to stimulus GO:0048584 37 0.010
regulation of catabolic process GO:0009894 199 0.010

RFA1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
cancer DOID:162 0 0.025