Saccharomyces cerevisiae

270 known processes

CDC28 (YBR160W)

Cdc28p

(Aliases: CDK1,SRM5,HSL5)

CDC28 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic cell cycle process GO:1903047 294 0.999
Yeast Mouse Worm Fly
nuclear division GO:0000280 263 0.999
mitotic cell cycle phase transition GO:0044772 141 0.999
Yeast Mouse Fly
meiotic cell cycle GO:0051321 272 0.999
meiotic nuclear division GO:0007126 163 0.999
regulation of protein phosphorylation GO:0001932 75 0.998
Worm
mitotic cell cycle GO:0000278 306 0.998
organelle fission GO:0048285 272 0.998
mitotic nuclear division GO:0007067 131 0.995
Worm
cell cycle phase transition GO:0044770 144 0.993
Yeast Mouse Fly
phosphorylation GO:0016310 291 0.988
protein phosphorylation GO:0006468 197 0.984
meiosis i GO:0007127 92 0.969
regulation of chromosome organization GO:0033044 66 0.957
regulation of cell cycle process GO:0010564 150 0.951
negative regulation of mitotic cell cycle GO:0045930 63 0.949
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 19 0.943
regulation of phosphorylation GO:0042325 86 0.942
Worm
regulation of cell cycle GO:0051726 195 0.942
cell cycle g1 s phase transition GO:0044843 64 0.941
Yeast Mouse Fly
g1 s transition of mitotic cell cycle GO:0000082 64 0.930
Yeast Mouse Fly
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.915
regulation of mitotic cell cycle GO:0007346 107 0.913
positive regulation of rna metabolic process GO:0051254 294 0.911
chromatin organization GO:0006325 242 0.898
positive regulation of cellular biosynthetic process GO:0031328 336 0.896
negative regulation of cell cycle process GO:0010948 86 0.881
microtubule cytoskeleton organization GO:0000226 109 0.878
cell cycle g2 m phase transition GO:0044839 39 0.875
Fly
positive regulation of macromolecule metabolic process GO:0010604 394 0.875
protein complex biogenesis GO:0070271 314 0.866
Rat
regulation of protein serine threonine kinase activity GO:0071900 41 0.860
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.860
regulation of kinase activity GO:0043549 71 0.853
Worm
protein complex assembly GO:0006461 302 0.851
Rat
regulation of protein kinase activity GO:0045859 67 0.841
Worm
negative regulation of cell cycle GO:0045786 91 0.841
mitotic spindle checkpoint GO:0071174 34 0.826
meiotic cell cycle process GO:1903046 229 0.826
regulation of biological quality GO:0065008 391 0.826
Yeast
spindle pole body organization GO:0051300 33 0.806
positive regulation of biosynthetic process GO:0009891 336 0.800
regulation of transferase activity GO:0051338 83 0.795
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.786
regulation of microtubule based process GO:0032886 32 0.774
chromatin modification GO:0016568 200 0.772
regulation of spindle pole body separation GO:0010695 9 0.771
cytoskeleton organization GO:0007010 230 0.771
microtubule organizing center organization GO:0031023 33 0.750
negative regulation of cell cycle phase transition GO:1901988 59 0.747
Mouse Fly
regulation of cellular protein metabolic process GO:0032268 232 0.744
Yeast Worm
single organism developmental process GO:0044767 258 0.726
Human Rat Worm Fly
dna packaging GO:0006323 55 0.721
Rat
cellular macromolecule catabolic process GO:0044265 363 0.710
positive regulation of transcription dna templated GO:0045893 286 0.702
regulation of mitotic cell cycle phase transition GO:1901990 68 0.674
Mouse Fly
vesicle mediated transport GO:0016192 335 0.673
chromosome segregation GO:0007059 159 0.657
cell division GO:0051301 205 0.654
protein localization to organelle GO:0033365 337 0.647
Human Rat
positive regulation of phosphorylation GO:0042327 33 0.646
Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.639
positive regulation of rna biosynthetic process GO:1902680 286 0.604
positive regulation of gene expression GO:0010628 321 0.601
negative regulation of biosynthetic process GO:0009890 312 0.595
spindle checkpoint GO:0031577 35 0.594
chromosome condensation GO:0030261 19 0.592
Rat
positive regulation of organelle organization GO:0010638 85 0.589
regulation of protein metabolic process GO:0051246 237 0.583
Yeast Worm
regulation of protein modification process GO:0031399 110 0.583
Worm
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 27 0.581
Yeast
negative regulation of cellular metabolic process GO:0031324 407 0.579
growth GO:0040007 157 0.570
regulation of cell cycle phase transition GO:1901987 70 0.548
Mouse Fly
maintenance of location GO:0051235 66 0.546
macromolecule catabolic process GO:0009057 383 0.540
positive regulation of protein phosphorylation GO:0001934 28 0.505
Worm
positive regulation of cellular component organization GO:0051130 116 0.501
protein dephosphorylation GO:0006470 40 0.482
regulation of molecular function GO:0065009 320 0.459
Yeast Worm
positive regulation of protein modification process GO:0031401 49 0.450
Worm
positive regulation of cell cycle GO:0045787 32 0.443
positive regulation of cytoskeleton organization GO:0051495 39 0.434
developmental process GO:0032502 261 0.425
Human Rat Worm Fly
dna conformation change GO:0071103 98 0.416
Rat
positive regulation of phosphorus metabolic process GO:0010562 147 0.415
Worm
regulation of mitosis GO:0007088 65 0.413
regulation of chromosome segregation GO:0051983 44 0.411
microtubule based process GO:0007017 117 0.410
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.391
positive regulation of nucleic acid templated transcription GO:1903508 286 0.387
regulation of localization GO:0032879 127 0.386
g2 m transition of mitotic cell cycle GO:0000086 38 0.376
Fly
regulation of dna metabolic process GO:0051052 100 0.376
proteolysis GO:0006508 268 0.374
regulation of response to stimulus GO:0048583 157 0.363
cell cycle dna replication GO:0044786 36 0.358
mitotic sister chromatid segregation GO:0000070 85 0.352
negative regulation of cellular protein metabolic process GO:0032269 85 0.350
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.325
Mouse Fly
protein modification by small protein conjugation or removal GO:0070647 172 0.321
mitotic cell cycle checkpoint GO:0007093 56 0.319
Mouse Fly
positive regulation of mitotic cell cycle GO:0045931 16 0.314
positive regulation of protein metabolic process GO:0051247 93 0.313
Yeast Worm
cytoskeleton dependent cytokinesis GO:0061640 65 0.309
single organism signaling GO:0044700 208 0.307
Human Yeast Fly
modification dependent protein catabolic process GO:0019941 181 0.291
regulation of organelle organization GO:0033043 243 0.290
regulation of catalytic activity GO:0050790 307 0.263
Worm
regulation of phosphate metabolic process GO:0019220 230 0.250
Yeast Worm
sister chromatid segregation GO:0000819 93 0.245
dna replication GO:0006260 147 0.242
cellular response to organic substance GO:0071310 159 0.238
Rat
regulation of nuclear division GO:0051783 103 0.215
Worm
peptidyl amino acid modification GO:0018193 116 0.214
anatomical structure morphogenesis GO:0009653 160 0.205
Fly
spindle organization GO:0007051 37 0.201
protein ubiquitination GO:0016567 118 0.200
regulation of cellular component organization GO:0051128 334 0.197
ubiquitin dependent protein catabolic process GO:0006511 181 0.195
positive regulation of cell communication GO:0010647 28 0.195
Yeast
cellular protein catabolic process GO:0044257 213 0.194
positive regulation of dna metabolic process GO:0051054 26 0.189
spindle assembly GO:0051225 9 0.183
negative regulation of gene expression GO:0010629 312 0.183
cell cycle checkpoint GO:0000075 82 0.181
Mouse Fly
mitotic cytokinesis GO:0000281 58 0.180
regulation of response to stress GO:0080134 57 0.178
modification dependent macromolecule catabolic process GO:0043632 203 0.177
regulation of dna replication GO:0006275 51 0.176
anatomical structure development GO:0048856 160 0.173
Human Rat Worm Fly
reproduction of a single celled organism GO:0032505 191 0.168
regulation of protein ubiquitination GO:0031396 20 0.165
cellular component disassembly GO:0022411 86 0.157
negative regulation of cellular biosynthetic process GO:0031327 312 0.154
maintenance of protein location GO:0045185 53 0.154
protein modification by small protein conjugation GO:0032446 144 0.153
positive regulation of phosphate metabolic process GO:0045937 147 0.153
Worm
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.150
mrna metabolic process GO:0016071 269 0.149
maintenance of location in cell GO:0051651 58 0.147
negative regulation of catabolic process GO:0009895 43 0.143
Yeast
response to organic substance GO:0010033 182 0.136
Rat
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.133
negative regulation of protein metabolic process GO:0051248 85 0.132
spindle pole body separation GO:0000073 13 0.131
external encapsulating structure organization GO:0045229 146 0.131
Yeast
negative regulation of molecular function GO:0044092 68 0.129
Yeast
mrna 3 end processing GO:0031124 54 0.127
Yeast
cytokinesis GO:0000910 92 0.126
dephosphorylation GO:0016311 127 0.123
negative regulation of rna metabolic process GO:0051253 262 0.123
regulation of protein localization GO:0032880 62 0.121
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.116
reproductive process GO:0022414 248 0.116
Worm Fly
regulation of microtubule cytoskeleton organization GO:0070507 32 0.115
positive regulation of spindle pole body separation GO:0010696 7 0.114
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.110
organelle assembly GO:0070925 118 0.108
negative regulation of macromolecule metabolic process GO:0010605 375 0.108
cellular response to chemical stimulus GO:0070887 315 0.107
Rat
regulation of exit from mitosis GO:0007096 29 0.107
cellular developmental process GO:0048869 191 0.107
Human Rat Worm Fly
regulation of cytoskeleton organization GO:0051493 63 0.105
regulation of meiotic cell cycle GO:0051445 43 0.104
sexual reproduction GO:0019953 216 0.102
Worm Fly
negative regulation of cellular component organization GO:0051129 109 0.099
regulation of phosphorus metabolic process GO:0051174 230 0.099
Yeast Worm
maintenance of protein location in cell GO:0032507 50 0.098
positive regulation of cell cycle process GO:0090068 31 0.094
posttranscriptional regulation of gene expression GO:0010608 115 0.092
Yeast
establishment of organelle localization GO:0051656 96 0.091
Worm
signaling GO:0023052 208 0.091
Human Yeast Fly
negative regulation of mitosis GO:0045839 39 0.090
organelle localization GO:0051640 128 0.089
Worm
regulation of cellular catabolic process GO:0031329 195 0.086
negative regulation of organelle organization GO:0010639 103 0.082
signal transduction GO:0007165 208 0.081
Human Yeast Fly
mitotic spindle organization GO:0007052 30 0.078
multi organism process GO:0051704 233 0.077
Worm Fly
rna 3 end processing GO:0031123 88 0.075
Yeast
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 35 0.072
response to organic cyclic compound GO:0014070 1 0.071
Rat
cellular protein complex assembly GO:0043623 209 0.067
regulation of cell communication GO:0010646 124 0.066
Yeast
regulation of signaling GO:0023051 119 0.066
Yeast
regulation of histone modification GO:0031056 18 0.064
regulation of protein catabolic process GO:0042176 40 0.064
response to external stimulus GO:0009605 158 0.064
Yeast
protein processing GO:0016485 64 0.063
regulation of cellular localization GO:0060341 50 0.062
Rat
regulation of cell division GO:0051302 113 0.062
mitotic metaphase plate congression GO:0007080 8 0.061
negative regulation of transcription dna templated GO:0045892 258 0.061
microtubule polymerization or depolymerization GO:0031109 36 0.060
positive regulation of dna replication GO:0045740 11 0.060
regulation of proteolysis GO:0030162 44 0.059
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.058
exit from mitosis GO:0010458 37 0.056
cellular response to oxygen containing compound GO:1901701 43 0.053
Rat
organic cyclic compound catabolic process GO:1901361 499 0.052
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.050
Yeast
macromolecular complex disassembly GO:0032984 80 0.049
mrna processing GO:0006397 185 0.048
glycosyl compound metabolic process GO:1901657 398 0.048
regulation of cellular protein catabolic process GO:1903362 36 0.047
nucleobase containing compound catabolic process GO:0034655 479 0.044
negative regulation of protein phosphorylation GO:0001933 24 0.043
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 27 0.043
programmed cell death GO:0012501 30 0.043
Human
regulation of anatomical structure size GO:0090066 50 0.042
cellular component morphogenesis GO:0032989 97 0.042
proteasomal protein catabolic process GO:0010498 141 0.042
developmental growth GO:0048589 3 0.041
Rat
response to temperature stimulus GO:0009266 74 0.040
reciprocal meiotic recombination GO:0007131 54 0.039
positive regulation of catalytic activity GO:0043085 178 0.039
Worm
regulation of cellular component size GO:0032535 50 0.038
chromosome separation GO:0051304 33 0.037
heterocycle catabolic process GO:0046700 494 0.036
response to metal ion GO:0010038 24 0.036
Rat
regulation of chromatin organization GO:1902275 23 0.036
protein maturation GO:0051604 76 0.034
negative regulation of cellular catabolic process GO:0031330 43 0.034
Yeast
negative regulation of cytoskeleton organization GO:0051494 24 0.033
regulation of mitotic spindle organization GO:0060236 8 0.033
regulation of cellular response to stress GO:0080135 50 0.033
negative regulation of protein maturation GO:1903318 33 0.033
regulation of protein processing GO:0070613 34 0.033
fungal type cell wall organization or biogenesis GO:0071852 169 0.033
Yeast
regulation of catabolic process GO:0009894 199 0.032
negative regulation of cellular protein catabolic process GO:1903363 27 0.031
regulation of protein dephosphorylation GO:0035304 4 0.030
negative regulation of protein catabolic process GO:0042177 27 0.030
regulation of gene silencing GO:0060968 41 0.030
Human
negative regulation of phosphate metabolic process GO:0045936 49 0.030
Yeast
membrane organization GO:0061024 276 0.029
negative regulation of protein processing GO:0010955 33 0.029
positive regulation of cellular catabolic process GO:0031331 128 0.029
regulation of chromatin modification GO:1903308 23 0.029
cell aging GO:0007569 70 0.028
Rat
response to nutrient levels GO:0031667 150 0.028
Yeast
microtubule based movement GO:0007018 18 0.028
positive regulation of molecular function GO:0044093 185 0.027
Worm
response to inorganic substance GO:0010035 47 0.027
Rat
cellular response to dna damage stimulus GO:0006974 287 0.027
death GO:0016265 30 0.026
Human
metaphase plate congression GO:0051310 8 0.026
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 24 0.026
regulation of dna dependent dna replication GO:0090329 37 0.026
protein catabolic process GO:0030163 221 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.026
response to abiotic stimulus GO:0009628 159 0.026
Rat
cell morphogenesis GO:0000902 30 0.025
negative regulation of proteasomal protein catabolic process GO:1901799 25 0.025
regulation of signal transduction GO:0009966 114 0.024
Yeast
negative regulation of proteolysis GO:0045861 33 0.024
negative regulation of protein modification process GO:0031400 37 0.024
response to chemical GO:0042221 390 0.023
Rat
regulation of protein maturation GO:1903317 34 0.023
negative regulation of protein depolymerization GO:1901880 12 0.023
chromosome localization GO:0050000 20 0.023
regulation of proteasomal protein catabolic process GO:0061136 34 0.023
negative regulation of phosphorus metabolic process GO:0010563 49 0.022
Yeast
protein complex disassembly GO:0043241 70 0.021
reciprocal dna recombination GO:0035825 54 0.021
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.021
positive regulation of transferase activity GO:0051347 28 0.021
Worm
negative regulation of catalytic activity GO:0043086 60 0.020
negative regulation of chromosome segregation GO:0051985 25 0.020
single organism reproductive process GO:0044702 159 0.020
Worm Fly
regulation of gene expression epigenetic GO:0040029 147 0.020
reproductive process in single celled organism GO:0022413 145 0.019
peptidyl serine modification GO:0018209 7 0.018
histone phosphorylation GO:0016572 3 0.018
Human Rat
negative regulation of rna biosynthetic process GO:1902679 260 0.017
attachment of spindle microtubules to kinetochore GO:0008608 25 0.017
regulation of cell size GO:0008361 30 0.017
negative regulation of cell division GO:0051782 66 0.017
regulation of chromatin silencing GO:0031935 39 0.016
chromatin silencing GO:0006342 147 0.016
protein depolymerization GO:0051261 21 0.016
positive regulation of catabolic process GO:0009896 135 0.016
regulation of protein depolymerization GO:1901879 12 0.016
positive regulation of chromatin modification GO:1903310 13 0.016
microtubule anchoring GO:0034453 25 0.016
regulation of transport GO:0051049 85 0.016
Rat
response to toxic substance GO:0009636 9 0.016
Rat
cell wall organization GO:0071555 146 0.016
Yeast
positive regulation of histone modification GO:0031058 12 0.016
negative regulation of protein complex disassembly GO:0043242 14 0.015
cellular lipid metabolic process GO:0044255 229 0.015
response to heat GO:0009408 69 0.015
cell death GO:0008219 30 0.015
Human
meiotic g2 mi transition GO:0008315 1 0.014
protein polymerization GO:0051258 51 0.014
response to hypoxia GO:0001666 4 0.014
spindle assembly checkpoint GO:0071173 23 0.013
response to oxygen containing compound GO:1901700 61 0.013
Rat
response to oxidative stress GO:0006979 99 0.013
Rat
autophagy GO:0006914 106 0.013
Yeast
establishment of protein localization to organelle GO:0072594 278 0.013
Rat
cellular response to heat GO:0034605 53 0.013
cell communication GO:0007154 345 0.013
Human Yeast Fly
negative regulation of phosphorylation GO:0042326 28 0.013
macroautophagy GO:0016236 55 0.013
Yeast
response to acid chemical GO:0001101 19 0.013
positive regulation of cellular component biogenesis GO:0044089 45 0.013
positive regulation of cellular protein metabolic process GO:0032270 89 0.012
Yeast Worm
purine containing compound metabolic process GO:0072521 400 0.012
regulation of chromosome condensation GO:0060623 2 0.012
cellular protein complex disassembly GO:0043624 42 0.012
cellular nitrogen compound catabolic process GO:0044270 494 0.012
regulation of spindle organization GO:0090224 8 0.012
covalent chromatin modification GO:0016569 119 0.012
Human Rat
regulation of ubiquitin protein transferase activity GO:0051438 8 0.011
positive regulation of protein ubiquitination GO:0031398 7 0.011
response to uv GO:0009411 4 0.011
cellular response to hypoxia GO:0071456 4 0.010
lipid biosynthetic process GO:0008610 170 0.010
positive regulation of chromosome organization GO:2001252 20 0.010
cellular polysaccharide biosynthetic process GO:0033692 38 0.010
Yeast

CDC28 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org