Saccharomyces cerevisiae

154 known processes

DOT1 (YDR440W)

Dot1p

(Aliases: PCH1)

DOT1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna recombination GO:0006310 172 0.507
cellular nitrogen compound catabolic process GO:0044270 494 0.354
chromatin silencing at telomere GO:0006348 84 0.262
dna repair GO:0006281 236 0.238
regulation of gene expression epigenetic GO:0040029 147 0.238
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.226
negative regulation of macromolecule metabolic process GO:0010605 375 0.212
heterocycle catabolic process GO:0046700 494 0.208
cellular response to dna damage stimulus GO:0006974 287 0.190
gene silencing GO:0016458 151 0.144
chromatin silencing GO:0006342 147 0.128
aromatic compound catabolic process GO:0019439 491 0.114
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.108
negative regulation of gene expression epigenetic GO:0045814 147 0.105
histone modification GO:0016570 119 0.104
covalent chromatin modification GO:0016569 119 0.103
organic cyclic compound catabolic process GO:1901361 499 0.094
chromatin silencing at silent mating type cassette GO:0030466 53 0.090
double strand break repair GO:0006302 105 0.079
macromolecule catabolic process GO:0009057 383 0.077
cellular macromolecule catabolic process GO:0044265 363 0.075
nucleobase containing compound catabolic process GO:0034655 479 0.069
regulation of protein modification process GO:0031399 110 0.065
conjugation GO:0000746 107 0.058
chromatin assembly GO:0031497 35 0.053
reproductive process GO:0022414 248 0.051
regulation of protein metabolic process GO:0051246 237 0.051
mrna metabolic process GO:0016071 269 0.051
regulation of response to stimulus GO:0048583 157 0.049
negative regulation of organelle organization GO:0010639 103 0.049
dna conformation change GO:0071103 98 0.047
peptidyl lysine modification GO:0018205 77 0.047
double strand break repair via homologous recombination GO:0000724 54 0.046
response to abiotic stimulus GO:0009628 159 0.045
autophagy GO:0006914 106 0.043
protein complex biogenesis GO:0070271 314 0.043
negative regulation of rna metabolic process GO:0051253 262 0.043
sexual reproduction GO:0019953 216 0.043
internal protein amino acid acetylation GO:0006475 52 0.042
regulation of organelle organization GO:0033043 243 0.041
protein complex assembly GO:0006461 302 0.040
dna dependent dna replication GO:0006261 115 0.040
chromatin organization GO:0006325 242 0.040
base excision repair GO:0006284 14 0.040
regulation of cellular component organization GO:0051128 334 0.039
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.037
regulation of cell communication GO:0010646 124 0.036
negative regulation of cellular component organization GO:0051129 109 0.035
internal peptidyl lysine acetylation GO:0018393 52 0.034
dna catabolic process endonucleolytic GO:0000737 31 0.034
negative regulation of cellular metabolic process GO:0031324 407 0.033
regulation of biological quality GO:0065008 391 0.033
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 79 0.033
regulation of dna replication GO:0006275 51 0.032
recombinational repair GO:0000725 64 0.032
developmental process GO:0032502 261 0.030
multi organism process GO:0051704 233 0.030
peptidyl amino acid modification GO:0018193 116 0.030
single organism catabolic process GO:0044712 619 0.030
reciprocal meiotic recombination GO:0007131 54 0.029
peptidyl lysine acetylation GO:0018394 52 0.029
negative regulation of cellular biosynthetic process GO:0031327 312 0.029
regulation of chromosome organization GO:0033044 66 0.028
purine containing compound metabolic process GO:0072521 400 0.028
intracellular protein transport GO:0006886 319 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.027
mitochondrion organization GO:0007005 261 0.027
negative regulation of nucleic acid templated transcription GO:1903507 260 0.026
negative regulation of transcription dna templated GO:0045892 258 0.026
dna catabolic process GO:0006308 42 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.025
macromolecule methylation GO:0043414 85 0.025
developmental process involved in reproduction GO:0003006 159 0.024
carboxylic acid metabolic process GO:0019752 338 0.024
mrna processing GO:0006397 185 0.024
cellular developmental process GO:0048869 191 0.022
organic acid metabolic process GO:0006082 352 0.022
regulation of hydrolase activity GO:0051336 133 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.022
protein alkylation GO:0008213 48 0.022
histone acetylation GO:0016573 51 0.021
nucleotide metabolic process GO:0009117 453 0.021
positive regulation of hydrolase activity GO:0051345 112 0.021
regulation of dna dependent dna replication GO:0090329 37 0.021
response to chemical GO:0042221 390 0.021
conjugation with cellular fusion GO:0000747 106 0.021
carbohydrate derivative catabolic process GO:1901136 339 0.020
purine ribonucleotide metabolic process GO:0009150 372 0.020
protein acylation GO:0043543 66 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.020
organonitrogen compound catabolic process GO:1901565 404 0.019
dna packaging GO:0006323 55 0.019
nuclear transport GO:0051169 165 0.019
regulation of cellular protein metabolic process GO:0032268 232 0.018
dna biosynthetic process GO:0071897 33 0.017
negative regulation of biosynthetic process GO:0009890 312 0.017
purine nucleoside metabolic process GO:0042278 380 0.017
regulation of molecular function GO:0065009 320 0.017
positive regulation of cellular catabolic process GO:0031331 128 0.017
regulation of signaling GO:0023051 119 0.017
meiotic cell cycle GO:0051321 272 0.017
purine nucleotide metabolic process GO:0006163 376 0.017
rna dependent dna replication GO:0006278 25 0.017
positive regulation of macromolecule metabolic process GO:0010604 394 0.017
response to organic cyclic compound GO:0014070 1 0.016
multi organism reproductive process GO:0044703 216 0.016
regulation of signal transduction GO:0009966 114 0.016
maintenance of dna repeat elements GO:0043570 20 0.016
purine ribonucleoside metabolic process GO:0046128 380 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
negative regulation of chromosome organization GO:2001251 39 0.015
positive regulation of apoptotic process GO:0043065 3 0.015
protein methylation GO:0006479 48 0.014
nucleoside catabolic process GO:0009164 335 0.014
regulation of dna templated transcription elongation GO:0032784 44 0.014
nucleoside phosphate catabolic process GO:1901292 331 0.013
cellular response to chemical stimulus GO:0070887 315 0.013
signal transduction GO:0007165 208 0.013
response to uv GO:0009411 4 0.013
cellular amino acid metabolic process GO:0006520 225 0.013
positive regulation of programmed cell death GO:0043068 3 0.013
methylation GO:0032259 101 0.013
dna replication GO:0006260 147 0.013
positive regulation of catabolic process GO:0009896 135 0.013
regulation of catabolic process GO:0009894 199 0.013
single organism developmental process GO:0044767 258 0.013
regulation of chromatin modification GO:1903308 23 0.013
anatomical structure formation involved in morphogenesis GO:0048646 136 0.012
protein acetylation GO:0006473 59 0.012
ribonucleoside triphosphate catabolic process GO:0009203 327 0.012
purine ribonucleotide catabolic process GO:0009154 327 0.012
purine nucleotide catabolic process GO:0006195 328 0.012
regulation of catalytic activity GO:0050790 307 0.012
regulation of dna metabolic process GO:0051052 100 0.011
regulation of meiotic cell cycle GO:0051445 43 0.011
negative regulation of dna replication GO:0008156 15 0.011
purine nucleoside catabolic process GO:0006152 330 0.011
establishment of protein localization GO:0045184 367 0.011
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.011
positive regulation of phosphate metabolic process GO:0045937 147 0.011
cell communication GO:0007154 345 0.011
membrane organization GO:0061024 276 0.010
positive regulation of cellular protein metabolic process GO:0032270 89 0.010
negative regulation of dna metabolic process GO:0051053 36 0.010
negative regulation of rna biosynthetic process GO:1902679 260 0.010

DOT1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org