Saccharomyces cerevisiae

143 known processes

GCN4 (YEL009C)

Gcn4p

(Aliases: AAS3,AAS101,ARG9)

GCN4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 338 0.574
positive regulation of transcription dna templated GO:0045893 286 0.454
positive regulation of rna metabolic process GO:0051254 294 0.453
oxoacid metabolic process GO:0043436 351 0.333
organic acid metabolic process GO:0006082 352 0.330
response to chemical GO:0042221 390 0.238
positive regulation of rna biosynthetic process GO:1902680 286 0.238
positive regulation of nucleic acid templated transcription GO:1903508 286 0.185
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.184
positive regulation of cellular biosynthetic process GO:0031328 336 0.181
developmental process GO:0032502 261 0.173
positive regulation of biosynthetic process GO:0009891 336 0.170
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.162
homeostatic process GO:0042592 227 0.160
positive regulation of gene expression GO:0010628 321 0.157
cellular carbohydrate metabolic process GO:0044262 135 0.152
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.151
cellular response to dna damage stimulus GO:0006974 287 0.145
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.143
cell communication GO:0007154 345 0.140
cellular response to chemical stimulus GO:0070887 315 0.131
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.130
positive regulation of macromolecule metabolic process GO:0010604 394 0.121
regulation of biological quality GO:0065008 391 0.120
protein localization to organelle GO:0033365 337 0.119
single organism developmental process GO:0044767 258 0.117
cellular developmental process GO:0048869 191 0.106
negative regulation of transcription dna templated GO:0045892 258 0.105
monocarboxylic acid metabolic process GO:0032787 122 0.103
single organism catabolic process GO:0044712 619 0.099
developmental process involved in reproduction GO:0003006 159 0.094
cellular carbohydrate catabolic process GO:0044275 33 0.091
generation of precursor metabolites and energy GO:0006091 147 0.086
nucleotide metabolic process GO:0009117 453 0.086
organophosphate metabolic process GO:0019637 597 0.086
organonitrogen compound biosynthetic process GO:1901566 314 0.085
response to organic substance GO:0010033 182 0.081
response to nutrient levels GO:0031667 150 0.081
protein complex assembly GO:0006461 302 0.077
dna repair GO:0006281 236 0.068
carbohydrate metabolic process GO:0005975 252 0.066
cellular amino acid metabolic process GO:0006520 225 0.065
chromatin remodeling GO:0006338 80 0.065
negative regulation of cellular metabolic process GO:0031324 407 0.062
purine ribonucleotide metabolic process GO:0009150 372 0.060
reproduction of a single celled organism GO:0032505 191 0.060
reproductive process GO:0022414 248 0.059
negative regulation of nucleic acid templated transcription GO:1903507 260 0.058
organic cyclic compound catabolic process GO:1901361 499 0.057
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.057
negative regulation of macromolecule metabolic process GO:0010605 375 0.056
transmembrane transport GO:0055085 349 0.055
response to external stimulus GO:0009605 158 0.055
purine ribonucleoside metabolic process GO:0046128 380 0.054
heterocycle catabolic process GO:0046700 494 0.053
carbon catabolite regulation of transcription GO:0045990 39 0.053
pyruvate metabolic process GO:0006090 37 0.052
anatomical structure development GO:0048856 160 0.051
aromatic compound catabolic process GO:0019439 491 0.050
fungal type cell wall organization or biogenesis GO:0071852 169 0.050
cellular nitrogen compound catabolic process GO:0044270 494 0.049
response to extracellular stimulus GO:0009991 156 0.049
negative regulation of rna biosynthetic process GO:1902679 260 0.048
lipid metabolic process GO:0006629 269 0.048
fungal type cell wall organization GO:0031505 145 0.047
nucleobase containing compound catabolic process GO:0034655 479 0.046
organonitrogen compound catabolic process GO:1901565 404 0.044
cellular amino acid biosynthetic process GO:0008652 118 0.044
ribose phosphate metabolic process GO:0019693 384 0.044
nitrogen compound transport GO:0071705 212 0.044
regulation of cellular catabolic process GO:0031329 195 0.044
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.042
ribonucleoside triphosphate metabolic process GO:0009199 356 0.041
regulation of mitotic cell cycle GO:0007346 107 0.041
cellular response to nutrient GO:0031670 50 0.041
regulation of response to stimulus GO:0048583 157 0.040
nucleoside phosphate metabolic process GO:0006753 458 0.039
cellular response to organic substance GO:0071310 159 0.039
cellular response to nutrient levels GO:0031669 144 0.039
negative regulation of cell cycle GO:0045786 91 0.037
mrna metabolic process GO:0016071 269 0.037
regulation of catabolic process GO:0009894 199 0.037
organic acid biosynthetic process GO:0016053 152 0.036
nucleobase containing compound transport GO:0015931 124 0.036
cellular cation homeostasis GO:0030003 100 0.035
purine nucleoside metabolic process GO:0042278 380 0.035
cellular ketone metabolic process GO:0042180 63 0.035
single organism reproductive process GO:0044702 159 0.035
regulation of carbohydrate metabolic process GO:0006109 43 0.035
multi organism process GO:0051704 233 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.034
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.034
multi organism reproductive process GO:0044703 216 0.033
mitotic cell cycle GO:0000278 306 0.033
regulation of cell cycle phase transition GO:1901987 70 0.033
cell growth GO:0016049 89 0.032
establishment of protein localization GO:0045184 367 0.032
phospholipid biosynthetic process GO:0008654 89 0.032
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.032
purine nucleoside catabolic process GO:0006152 330 0.032
nucleoside monophosphate metabolic process GO:0009123 267 0.031
chromatin organization GO:0006325 242 0.031
sexual reproduction GO:0019953 216 0.031
purine nucleotide metabolic process GO:0006163 376 0.030
oxidation reduction process GO:0055114 353 0.030
cell aging GO:0007569 70 0.030
glycosyl compound catabolic process GO:1901658 335 0.029
protein complex biogenesis GO:0070271 314 0.029
cell wall organization GO:0071555 146 0.029
cellular ion homeostasis GO:0006873 112 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.028
cell wall organization or biogenesis GO:0071554 190 0.028
regulation of phosphorus metabolic process GO:0051174 230 0.027
nucleoside triphosphate metabolic process GO:0009141 364 0.027
g1 s transition of mitotic cell cycle GO:0000082 64 0.027
anion transport GO:0006820 145 0.027
establishment of protein localization to organelle GO:0072594 278 0.027
cellular response to oxidative stress GO:0034599 94 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.027
cellular homeostasis GO:0019725 138 0.027
filamentous growth GO:0030447 124 0.027
regulation of cellular component organization GO:0051128 334 0.027
purine containing compound catabolic process GO:0072523 332 0.026
transcription initiation from rna polymerase ii promoter GO:0006367 55 0.026
cell cycle phase transition GO:0044770 144 0.026
chromatin modification GO:0016568 200 0.026
purine containing compound metabolic process GO:0072521 400 0.026
protein targeting GO:0006605 272 0.026
ribonucleotide catabolic process GO:0009261 327 0.026
single organism cellular localization GO:1902580 375 0.026
purine nucleoside triphosphate catabolic process GO:0009146 329 0.026
multi organism cellular process GO:0044764 120 0.025
ribonucleoside catabolic process GO:0042454 332 0.025
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 34 0.025
negative regulation of mitotic cell cycle GO:0045930 63 0.025
single organism carbohydrate catabolic process GO:0044724 73 0.024
chemical homeostasis GO:0048878 137 0.024
nucleic acid transport GO:0050657 94 0.024
ascospore formation GO:0030437 107 0.024
growth GO:0040007 157 0.023
reproductive process in single celled organism GO:0022413 145 0.023
regulation of generation of precursor metabolites and energy GO:0043467 23 0.023
organophosphate biosynthetic process GO:0090407 182 0.023
chromatin silencing GO:0006342 147 0.023
negative regulation of rna metabolic process GO:0051253 262 0.023
anatomical structure morphogenesis GO:0009653 160 0.023
ribonucleoside metabolic process GO:0009119 389 0.023
external encapsulating structure organization GO:0045229 146 0.023
negative regulation of cellular biosynthetic process GO:0031327 312 0.022
mitotic cell cycle process GO:1903047 294 0.022
carbohydrate derivative catabolic process GO:1901136 339 0.022
response to inorganic substance GO:0010035 47 0.022
cellular response to extracellular stimulus GO:0031668 150 0.022
cell fate commitment GO:0045165 32 0.022
mrna export from nucleus GO:0006406 60 0.022
telomere maintenance GO:0000723 74 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.022
ribonucleotide metabolic process GO:0009259 377 0.022
nuclear division GO:0000280 263 0.022
macromolecule catabolic process GO:0009057 383 0.022
carbohydrate derivative metabolic process GO:1901135 549 0.022
purine ribonucleoside catabolic process GO:0046130 330 0.022
mitotic nuclear division GO:0007067 131 0.021
small molecule biosynthetic process GO:0044283 258 0.021
cell differentiation GO:0030154 161 0.021
nucleotide catabolic process GO:0009166 330 0.021
lipid biosynthetic process GO:0008610 170 0.021
metal ion homeostasis GO:0055065 79 0.021
purine nucleoside monophosphate metabolic process GO:0009126 262 0.021
chromatin assembly or disassembly GO:0006333 60 0.021
anatomical structure homeostasis GO:0060249 74 0.021
ion transport GO:0006811 274 0.021
nucleobase containing small molecule metabolic process GO:0055086 491 0.021
regulation of molecular function GO:0065009 320 0.021
signal transduction GO:0007165 208 0.021
regulation of dna metabolic process GO:0051052 100 0.021
mrna catabolic process GO:0006402 93 0.020
glycosyl compound metabolic process GO:1901657 398 0.020
positive regulation of phosphorus metabolic process GO:0010562 147 0.020
nucleoside catabolic process GO:0009164 335 0.020
cation homeostasis GO:0055080 105 0.020
regulation of cell cycle process GO:0010564 150 0.020
organic hydroxy compound metabolic process GO:1901615 125 0.020
cell division GO:0051301 205 0.020
energy derivation by oxidation of organic compounds GO:0015980 125 0.020
establishment of rna localization GO:0051236 92 0.020
cytoskeleton organization GO:0007010 230 0.020
purine ribonucleotide catabolic process GO:0009154 327 0.020
maintenance of protein location in cell GO:0032507 50 0.020
intracellular protein transport GO:0006886 319 0.019
carboxylic acid biosynthetic process GO:0046394 152 0.019
single organism signaling GO:0044700 208 0.019
negative regulation of gene expression GO:0010629 312 0.019
double strand break repair GO:0006302 105 0.019
regulation of organelle organization GO:0033043 243 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.019
cellular macromolecule catabolic process GO:0044265 363 0.019
organophosphate catabolic process GO:0046434 338 0.019
protein dna complex assembly GO:0065004 105 0.019
single organism carbohydrate metabolic process GO:0044723 237 0.019
telomere capping GO:0016233 10 0.018
small molecule catabolic process GO:0044282 88 0.018
cellular carbohydrate biosynthetic process GO:0034637 49 0.018
phospholipid metabolic process GO:0006644 125 0.018
response to organic cyclic compound GO:0014070 1 0.018
response to oxygen containing compound GO:1901700 61 0.018
filamentous growth of a population of unicellular organisms GO:0044182 109 0.018
cellular metal ion homeostasis GO:0006875 78 0.018
regulation of mitotic cell cycle phase transition GO:1901990 68 0.018
regulation of filamentous growth of a population of unicellular organisms GO:1900428 36 0.018
mitotic cytokinesis GO:0000281 58 0.018
cellular lipid metabolic process GO:0044255 229 0.017
nucleoside metabolic process GO:0009116 394 0.017
cellular amine metabolic process GO:0044106 51 0.017
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 79 0.017
internal protein amino acid acetylation GO:0006475 52 0.017
macroautophagy GO:0016236 55 0.017
regulation of catalytic activity GO:0050790 307 0.017
positive regulation of molecular function GO:0044093 185 0.017
rna 3 end processing GO:0031123 88 0.017
dna replication GO:0006260 147 0.017
dna templated transcription termination GO:0006353 42 0.017
protein transport GO:0015031 345 0.017
positive regulation of cellular component organization GO:0051130 116 0.017
negative regulation of biosynthetic process GO:0009890 312 0.017
replicative cell aging GO:0001302 46 0.017
internal peptidyl lysine acetylation GO:0018393 52 0.017
cell cycle g1 s phase transition GO:0044843 64 0.017
cellular lipid catabolic process GO:0044242 33 0.016
carbohydrate catabolic process GO:0016052 77 0.016
dna templated transcription initiation GO:0006352 71 0.016
cytokinesis GO:0000910 92 0.016
cell development GO:0048468 107 0.016
maintenance of location in cell GO:0051651 58 0.016
dna dependent dna replication GO:0006261 115 0.016
nucleoside triphosphate catabolic process GO:0009143 329 0.016
regulation of phosphate metabolic process GO:0019220 230 0.016
protein acylation GO:0043543 66 0.016
mrna transport GO:0051028 60 0.016
purine nucleoside triphosphate metabolic process GO:0009144 356 0.016
response to pheromone GO:0019236 92 0.015
regulation of cellular amino acid metabolic process GO:0006521 16 0.015
mitochondrion organization GO:0007005 261 0.015
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.015
ion homeostasis GO:0050801 118 0.015
peptidyl lysine modification GO:0018205 77 0.015
negative regulation of cell cycle phase transition GO:1901988 59 0.015
cleavage involved in rrna processing GO:0000469 69 0.015
response to hypoxia GO:0001666 4 0.015
chromosome segregation GO:0007059 159 0.015
nucleoside phosphate catabolic process GO:1901292 331 0.015
carboxylic acid transport GO:0046942 74 0.015
purine nucleotide catabolic process GO:0006195 328 0.015
aging GO:0007568 71 0.015
microtubule based process GO:0007017 117 0.015
mitotic cell cycle phase transition GO:0044772 141 0.015
response to nutrient GO:0007584 52 0.015
organic anion transport GO:0015711 114 0.014
alpha amino acid biosynthetic process GO:1901607 91 0.014
positive regulation of apoptotic process GO:0043065 3 0.014
anatomical structure formation involved in morphogenesis GO:0048646 136 0.014
regulation of protein complex assembly GO:0043254 77 0.014
cellular component morphogenesis GO:0032989 97 0.014
telomere maintenance via telomere lengthening GO:0010833 22 0.014
peroxisome organization GO:0007031 68 0.014
cellular protein complex assembly GO:0043623 209 0.014
cell wall biogenesis GO:0042546 93 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.014
positive regulation of phosphate metabolic process GO:0045937 147 0.014
maintenance of location GO:0051235 66 0.014
establishment of protein localization to vacuole GO:0072666 91 0.014
signaling GO:0023052 208 0.014
response to drug GO:0042493 41 0.014
rna catabolic process GO:0006401 118 0.014
glycerophospholipid biosynthetic process GO:0046474 68 0.013
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 40 0.013
regulation of cellular ketone metabolic process GO:0010565 42 0.013
protein dna complex subunit organization GO:0071824 153 0.013
rna phosphodiester bond hydrolysis GO:0090501 112 0.013
cellular chemical homeostasis GO:0055082 123 0.013
ribonucleoprotein complex assembly GO:0022618 143 0.013
rna export from nucleus GO:0006405 88 0.013
histone acetylation GO:0016573 51 0.013
dna templated transcriptional preinitiation complex assembly GO:0070897 51 0.013
translational initiation GO:0006413 56 0.013
regulation of growth of unicellular organism as a thread of attached cells GO:0070784 31 0.013
meiotic cell cycle process GO:1903046 229 0.013
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.013
protein acetylation GO:0006473 59 0.013
dephosphorylation GO:0016311 127 0.013
meiotic cell cycle GO:0051321 272 0.013
dna templated transcription elongation GO:0006354 91 0.013
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.013
positive regulation of cell death GO:0010942 3 0.012
nucleoside monophosphate catabolic process GO:0009125 224 0.012
mating type switching GO:0007533 28 0.012
positive regulation of programmed cell death GO:0043068 3 0.012
mrna 3 end processing GO:0031124 54 0.012
regulation of gene silencing GO:0060968 41 0.012
protein localization to nucleus GO:0034504 74 0.012
cytokinetic process GO:0032506 78 0.012
cellular response to external stimulus GO:0071496 150 0.012
dna integrity checkpoint GO:0031570 41 0.012
regulation of growth GO:0040008 50 0.012
endonucleolytic cleavage involved in rrna processing GO:0000478 47 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.012
gtp metabolic process GO:0046039 107 0.012
ribonucleoside monophosphate metabolic process GO:0009161 265 0.012
regulation of nucleoside metabolic process GO:0009118 106 0.012
phosphorylation GO:0016310 291 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.012
conjugation with cellular fusion GO:0000747 106 0.012
dna packaging GO:0006323 55 0.012
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000479 47 0.012
rna transport GO:0050658 92 0.012
regulation of response to stress GO:0080134 57 0.012
rna localization GO:0006403 112 0.012
peptidyl amino acid modification GO:0018193 116 0.012
regulation of cell communication GO:0010646 124 0.012
macromolecular complex disassembly GO:0032984 80 0.011
regulation of protein modification process GO:0031399 110 0.011
ras protein signal transduction GO:0007265 29 0.011
regulation of filamentous growth GO:0010570 38 0.011
rna splicing GO:0008380 131 0.011
nuclear transcribed mrna catabolic process GO:0000956 89 0.011
cytoskeleton dependent cytokinesis GO:0061640 65 0.011
dna conformation change GO:0071103 98 0.011
amine metabolic process GO:0009308 51 0.011
nitrogen utilization GO:0019740 21 0.011
negative regulation of organelle organization GO:0010639 103 0.011
polysaccharide metabolic process GO:0005976 60 0.011
glycerophospholipid metabolic process GO:0006650 98 0.011
positive regulation of organelle organization GO:0010638 85 0.011
organelle assembly GO:0070925 118 0.011
termination of rna polymerase ii transcription GO:0006369 26 0.011
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 80 0.011
ribonucleoside triphosphate catabolic process GO:0009203 327 0.011
organic acid catabolic process GO:0016054 71 0.011
regulation of gene expression epigenetic GO:0040029 147 0.011
sexual sporulation GO:0034293 113 0.011
dna replication initiation GO:0006270 48 0.011
carbohydrate derivative biosynthetic process GO:1901137 181 0.011
modification dependent macromolecule catabolic process GO:0043632 203 0.010
regulation of purine nucleotide catabolic process GO:0033121 106 0.010
ribonucleoside monophosphate catabolic process GO:0009158 224 0.010
gene silencing GO:0016458 151 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.010
positive regulation of peroxisome organization by positive regulation of transcription from rna polymerase ii promoter GO:0061424 1 0.010
positive regulation of catabolic process GO:0009896 135 0.010
transition metal ion homeostasis GO:0055076 59 0.010
regulation of chromatin silencing GO:0031935 39 0.010
proteolysis GO:0006508 268 0.010
monocarboxylic acid biosynthetic process GO:0072330 35 0.010
sex determination GO:0007530 32 0.010
fungal type cell wall biogenesis GO:0009272 80 0.010
cellular component disassembly GO:0022411 86 0.010
protein complex disassembly GO:0043241 70 0.010
apoptotic process GO:0006915 30 0.010
carbohydrate biosynthetic process GO:0016051 82 0.010
atp catabolic process GO:0006200 224 0.010

GCN4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019