Saccharomyces cerevisiae

40 known processes

HIS2 (YFR025C)

His2p

HIS2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound biosynthetic process GO:1901566 314 0.368
organic acid metabolic process GO:0006082 352 0.347
alpha amino acid metabolic process GO:1901605 124 0.294
alpha amino acid biosynthetic process GO:1901607 91 0.194
cellular amino acid biosynthetic process GO:0008652 118 0.184
oxoacid metabolic process GO:0043436 351 0.182
small molecule biosynthetic process GO:0044283 258 0.172
carboxylic acid metabolic process GO:0019752 338 0.153
carboxylic acid biosynthetic process GO:0046394 152 0.133
organic acid biosynthetic process GO:0016053 152 0.110
cellular amino acid metabolic process GO:0006520 225 0.100
cofactor metabolic process GO:0051186 126 0.093
coenzyme metabolic process GO:0006732 104 0.090
single organism catabolic process GO:0044712 619 0.073
organophosphate metabolic process GO:0019637 597 0.061
nucleobase containing small molecule metabolic process GO:0055086 491 0.058
nitrogen compound transport GO:0071705 212 0.056
negative regulation of cellular metabolic process GO:0031324 407 0.053
signaling GO:0023052 208 0.053
single organism signaling GO:0044700 208 0.052
cell division GO:0051301 205 0.050
cofactor biosynthetic process GO:0051188 80 0.047
regulation of biological quality GO:0065008 391 0.045
cell communication GO:0007154 345 0.044
carbohydrate derivative metabolic process GO:1901135 549 0.039
single organism carbohydrate metabolic process GO:0044723 237 0.038
proteolysis GO:0006508 268 0.038
coenzyme biosynthetic process GO:0009108 66 0.038
carboxylic acid transport GO:0046942 74 0.038
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.038
cellular macromolecule catabolic process GO:0044265 363 0.037
lipid metabolic process GO:0006629 269 0.036
macromolecule catabolic process GO:0009057 383 0.035
pyridine containing compound metabolic process GO:0072524 53 0.035
homeostatic process GO:0042592 227 0.035
aromatic compound catabolic process GO:0019439 491 0.034
organic cyclic compound catabolic process GO:1901361 499 0.034
pyridine nucleotide metabolic process GO:0019362 45 0.032
organophosphate biosynthetic process GO:0090407 182 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.031
nucleoside phosphate metabolic process GO:0006753 458 0.031
signal transduction GO:0007165 208 0.030
protein catabolic process GO:0030163 221 0.030
modification dependent macromolecule catabolic process GO:0043632 203 0.029
nucleotide metabolic process GO:0009117 453 0.029
cellular homeostasis GO:0019725 138 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.029
nicotinamide nucleotide metabolic process GO:0046496 44 0.029
cytoskeleton organization GO:0007010 230 0.028
organic anion transport GO:0015711 114 0.027
response to organic substance GO:0010033 182 0.026
cellular lipid metabolic process GO:0044255 229 0.026
mitotic cell cycle GO:0000278 306 0.026
protein complex biogenesis GO:0070271 314 0.026
carbohydrate metabolic process GO:0005975 252 0.025
protein complex assembly GO:0006461 302 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.025
negative regulation of macromolecule metabolic process GO:0010605 375 0.024
oxidoreduction coenzyme metabolic process GO:0006733 58 0.024
cellular nitrogen compound catabolic process GO:0044270 494 0.024
negative regulation of biosynthetic process GO:0009890 312 0.023
regulation of catabolic process GO:0009894 199 0.023
negative regulation of cellular biosynthetic process GO:0031327 312 0.023
organelle fission GO:0048285 272 0.023
cation transport GO:0006812 166 0.022
glycosyl compound metabolic process GO:1901657 398 0.022
response to organic cyclic compound GO:0014070 1 0.022
mitotic cell cycle process GO:1903047 294 0.022
regulation of cellular component organization GO:0051128 334 0.022
cellular protein complex assembly GO:0043623 209 0.021
ncrna processing GO:0034470 330 0.021
organic acid transport GO:0015849 77 0.021
nucleobase containing compound catabolic process GO:0034655 479 0.021
cellular chemical homeostasis GO:0055082 123 0.020
cellular protein catabolic process GO:0044257 213 0.020
modification dependent protein catabolic process GO:0019941 181 0.020
carboxylic acid catabolic process GO:0046395 71 0.020
ubiquitin dependent protein catabolic process GO:0006511 181 0.020
anion transport GO:0006820 145 0.020
response to abiotic stimulus GO:0009628 159 0.020
water soluble vitamin metabolic process GO:0006767 41 0.020
organonitrogen compound catabolic process GO:1901565 404 0.019
response to chemical GO:0042221 390 0.019
rrna processing GO:0006364 227 0.019
positive regulation of gene expression GO:0010628 321 0.018
monocarboxylic acid metabolic process GO:0032787 122 0.018
carbohydrate derivative biosynthetic process GO:1901137 181 0.018
carbohydrate derivative catabolic process GO:1901136 339 0.018
rrna metabolic process GO:0016072 244 0.018
nuclear division GO:0000280 263 0.018
establishment of protein localization GO:0045184 367 0.017
ion homeostasis GO:0050801 118 0.017
regulation of catalytic activity GO:0050790 307 0.017
regulation of organelle organization GO:0033043 243 0.017
nucleoside metabolic process GO:0009116 394 0.017
reproduction of a single celled organism GO:0032505 191 0.017
phosphorylation GO:0016310 291 0.017
nicotinamide nucleotide biosynthetic process GO:0019359 16 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.017
regulation of response to stimulus GO:0048583 157 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.017
ribonucleoside metabolic process GO:0009119 389 0.017
developmental process GO:0032502 261 0.016
heterocycle catabolic process GO:0046700 494 0.016
negative regulation of rna metabolic process GO:0051253 262 0.016
regulation of protein metabolic process GO:0051246 237 0.016
single organism cellular localization GO:1902580 375 0.016
negative regulation of gene expression GO:0010629 312 0.016
vitamin biosynthetic process GO:0009110 38 0.016
cellular response to chemical stimulus GO:0070887 315 0.016
purine containing compound metabolic process GO:0072521 400 0.016
nucleobase containing compound transport GO:0015931 124 0.016
purine ribonucleotide metabolic process GO:0009150 372 0.016
organic acid catabolic process GO:0016054 71 0.015
amine metabolic process GO:0009308 51 0.015
pyridine nucleotide biosynthetic process GO:0019363 17 0.015
translation GO:0006412 230 0.015
regulation of molecular function GO:0065009 320 0.015
chemical homeostasis GO:0048878 137 0.015
positive regulation of macromolecule metabolic process GO:0010604 394 0.015
regulation of cellular catabolic process GO:0031329 195 0.015
positive regulation of biosynthetic process GO:0009891 336 0.015
telomere organization GO:0032200 75 0.015
purine nucleoside catabolic process GO:0006152 330 0.014
nucleoside phosphate biosynthetic process GO:1901293 80 0.014
cellular response to organic substance GO:0071310 159 0.014
purine nucleotide metabolic process GO:0006163 376 0.014
filamentous growth GO:0030447 124 0.014
glutamine family amino acid biosynthetic process GO:0009084 18 0.014
purine nucleoside metabolic process GO:0042278 380 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.014
glycosyl compound catabolic process GO:1901658 335 0.014
ribonucleotide metabolic process GO:0009259 377 0.014
negative regulation of cellular component organization GO:0051129 109 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.013
purine ribonucleoside metabolic process GO:0046128 380 0.013
cellular amine metabolic process GO:0044106 51 0.013
multi organism reproductive process GO:0044703 216 0.013
regulation of dna metabolic process GO:0051052 100 0.013
ribonucleoside catabolic process GO:0042454 332 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.013
positive regulation of nucleic acid templated transcription GO:1903508 286 0.013
cellular carbohydrate metabolic process GO:0044262 135 0.013
cellular biogenic amine metabolic process GO:0006576 37 0.013
small molecule catabolic process GO:0044282 88 0.012
purine nucleoside triphosphate catabolic process GO:0009146 329 0.012
mitotic recombination GO:0006312 55 0.012
regulation of signal transduction GO:0009966 114 0.012
single organism developmental process GO:0044767 258 0.012
fungal type cell wall organization or biogenesis GO:0071852 169 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.012
negative regulation of nucleic acid templated transcription GO:1903507 260 0.012
vitamin metabolic process GO:0006766 41 0.012
anatomical structure development GO:0048856 160 0.012
mitochondrial transport GO:0006839 76 0.012
ribonucleoprotein complex assembly GO:0022618 143 0.012
nad metabolic process GO:0019674 25 0.012
chromosome segregation GO:0007059 159 0.012
proteasomal protein catabolic process GO:0010498 141 0.012
oxidation reduction process GO:0055114 353 0.012
ribosome biogenesis GO:0042254 335 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.011
ribose phosphate metabolic process GO:0019693 384 0.011
glutamine family amino acid metabolic process GO:0009064 31 0.011
nad biosynthetic process GO:0009435 13 0.011
negative regulation of transcription dna templated GO:0045892 258 0.011
negative regulation of rna biosynthetic process GO:1902679 260 0.011
dna dependent dna replication GO:0006261 115 0.011
positive regulation of programmed cell death GO:0043068 3 0.011
regulation of cellular protein metabolic process GO:0032268 232 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.011
protein localization to organelle GO:0033365 337 0.011
organelle localization GO:0051640 128 0.011
monocarboxylic acid catabolic process GO:0072329 26 0.011
dna replication GO:0006260 147 0.011
cellular developmental process GO:0048869 191 0.011
sporulation GO:0043934 132 0.011
aging GO:0007568 71 0.011
ribonucleoprotein complex subunit organization GO:0071826 152 0.011
protein localization to membrane GO:0072657 102 0.011
intracellular signal transduction GO:0035556 112 0.011
regulation of intracellular signal transduction GO:1902531 78 0.011
mitotic sister chromatid segregation GO:0000070 85 0.010
positive regulation of cellular biosynthetic process GO:0031328 336 0.010
developmental process involved in reproduction GO:0003006 159 0.010
filamentous growth of a population of unicellular organisms GO:0044182 109 0.010
mitotic nuclear division GO:0007067 131 0.010
positive regulation of cellular catabolic process GO:0031331 128 0.010
peroxisome organization GO:0007031 68 0.010
sister chromatid segregation GO:0000819 93 0.010
cellular metal ion homeostasis GO:0006875 78 0.010
nucleoside triphosphate metabolic process GO:0009141 364 0.010
telomere maintenance GO:0000723 74 0.010
positive regulation of cell death GO:0010942 3 0.010
mitochondrion organization GO:0007005 261 0.010
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.010
regulation of translation GO:0006417 89 0.010
nucleoside catabolic process GO:0009164 335 0.010
response to osmotic stress GO:0006970 83 0.010
transmembrane transport GO:0055085 349 0.010

HIS2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.010