Saccharomyces cerevisiae

78 known processes

VPS13 (YLL040C)

Vps13p

(Aliases: VPT2,SOI1)

VPS13 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
fungal type cell wall organization or biogenesis GO:0071852 169 0.686
reproductive process GO:0022414 248 0.620
external encapsulating structure organization GO:0045229 146 0.597
fungal type cell wall organization GO:0031505 145 0.466
sexual reproduction GO:0019953 216 0.422
cell wall organization or biogenesis GO:0071554 190 0.415
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.360
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.355
meiotic cell cycle GO:0051321 272 0.353
single organism reproductive process GO:0044702 159 0.353
ribose phosphate metabolic process GO:0019693 384 0.338
single organism cellular localization GO:1902580 375 0.326
establishment of protein localization to vacuole GO:0072666 91 0.322
negative regulation of rna metabolic process GO:0051253 262 0.317
exocytosis GO:0006887 42 0.299
anatomical structure development GO:0048856 160 0.292
negative regulation of cellular biosynthetic process GO:0031327 312 0.287
nucleobase containing small molecule metabolic process GO:0055086 491 0.268
signaling GO:0023052 208 0.262
organophosphate metabolic process GO:0019637 597 0.260
cellular component assembly involved in morphogenesis GO:0010927 73 0.256
cell wall organization GO:0071555 146 0.254
golgi vesicle transport GO:0048193 188 0.253
signal transduction GO:0007165 208 0.253
vesicle organization GO:0016050 68 0.250
negative regulation of biosynthetic process GO:0009890 312 0.248
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.247
response to chemical GO:0042221 390 0.244
negative regulation of cellular metabolic process GO:0031324 407 0.241
single organism membrane organization GO:0044802 275 0.238
energy derivation by oxidation of organic compounds GO:0015980 125 0.232
multi organism process GO:0051704 233 0.232
negative regulation of nucleic acid templated transcription GO:1903507 260 0.217
reproductive process in single celled organism GO:0022413 145 0.215
membrane organization GO:0061024 276 0.206
sexual sporulation GO:0034293 113 0.206
establishment of protein localization GO:0045184 367 0.202
protein transport GO:0015031 345 0.201
dna replication GO:0006260 147 0.200
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.197
single organism signaling GO:0044700 208 0.178
generation of precursor metabolites and energy GO:0006091 147 0.177
multi organism reproductive process GO:0044703 216 0.173
cell communication GO:0007154 345 0.171
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.166
anatomical structure formation involved in morphogenesis GO:0048646 136 0.164
intracellular protein transport GO:0006886 319 0.158
purine ribonucleoside metabolic process GO:0046128 380 0.158
vacuolar transport GO:0007034 145 0.158
conjugation GO:0000746 107 0.153
regulation of molecular function GO:0065009 320 0.152
ascospore formation GO:0030437 107 0.142
cellular component morphogenesis GO:0032989 97 0.139
purine ribonucleotide catabolic process GO:0009154 327 0.137
cell differentiation GO:0030154 161 0.137
cellular developmental process GO:0048869 191 0.135
protein targeting GO:0006605 272 0.135
nucleotide catabolic process GO:0009166 330 0.129
regulation of cellular component organization GO:0051128 334 0.125
purine ribonucleoside catabolic process GO:0046130 330 0.120
reproduction of a single celled organism GO:0032505 191 0.119
ribonucleoside triphosphate metabolic process GO:0009199 356 0.117
response to external stimulus GO:0009605 158 0.116
glycosyl compound metabolic process GO:1901657 398 0.116
organelle assembly GO:0070925 118 0.114
negative regulation of rna biosynthetic process GO:1902679 260 0.114
meiotic cell cycle process GO:1903046 229 0.111
developmental process GO:0032502 261 0.109
oxidation reduction process GO:0055114 353 0.106
negative regulation of macromolecule metabolic process GO:0010605 375 0.105
purine nucleotide catabolic process GO:0006195 328 0.105
anatomical structure morphogenesis GO:0009653 160 0.103
cellular response to external stimulus GO:0071496 150 0.101
ribonucleoside monophosphate metabolic process GO:0009161 265 0.101
phosphatidylinositol metabolic process GO:0046488 62 0.098
cell wall biogenesis GO:0042546 93 0.097
macromolecule catabolic process GO:0009057 383 0.097
heterocycle catabolic process GO:0046700 494 0.097
ribonucleotide metabolic process GO:0009259 377 0.092
ribonucleotide catabolic process GO:0009261 327 0.091
regulation of cellular localization GO:0060341 50 0.090
carbohydrate metabolic process GO:0005975 252 0.088
organic cyclic compound catabolic process GO:1901361 499 0.083
negative regulation of gene expression GO:0010629 312 0.082
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.082
cell development GO:0048468 107 0.082
single organism developmental process GO:0044767 258 0.078
response to starvation GO:0042594 96 0.077
developmental process involved in reproduction GO:0003006 159 0.077
carbohydrate derivative metabolic process GO:1901135 549 0.077
nucleoside phosphate catabolic process GO:1901292 331 0.076
regulation of response to stimulus GO:0048583 157 0.075
secretion GO:0046903 50 0.075
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.074
regulation of localization GO:0032879 127 0.073
regulation of catalytic activity GO:0050790 307 0.072
gene silencing GO:0016458 151 0.072
ribonucleoside catabolic process GO:0042454 332 0.070
purine nucleotide metabolic process GO:0006163 376 0.070
establishment of protein localization to organelle GO:0072594 278 0.070
purine nucleoside monophosphate catabolic process GO:0009128 224 0.069
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.069
positive regulation of catalytic activity GO:0043085 178 0.068
cellular response to starvation GO:0009267 90 0.067
aromatic compound catabolic process GO:0019439 491 0.066
regulation of signal transduction GO:0009966 114 0.066
nucleoside triphosphate catabolic process GO:0009143 329 0.065
ribonucleoside triphosphate catabolic process GO:0009203 327 0.065
nucleoside triphosphate metabolic process GO:0009141 364 0.064
regulation of phosphate metabolic process GO:0019220 230 0.063
protein targeting to vacuole GO:0006623 91 0.063
nucleoside catabolic process GO:0009164 335 0.062
negative regulation of transcription dna templated GO:0045892 258 0.061
sporulation resulting in formation of a cellular spore GO:0030435 129 0.060
single organism catabolic process GO:0044712 619 0.059
macroautophagy GO:0016236 55 0.059
nucleotide metabolic process GO:0009117 453 0.059
response to extracellular stimulus GO:0009991 156 0.059
cellular response to chemical stimulus GO:0070887 315 0.057
vacuole organization GO:0007033 75 0.056
cellular response to organic substance GO:0071310 159 0.055
purine nucleoside triphosphate metabolic process GO:0009144 356 0.055
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.053
regulation of cell communication GO:0010646 124 0.051
sporulation GO:0043934 132 0.051
cellular response to nutrient levels GO:0031669 144 0.051
detection of stimulus GO:0051606 4 0.051
nucleoside phosphate metabolic process GO:0006753 458 0.050
regulation of ras protein signal transduction GO:0046578 47 0.049
autophagy GO:0006914 106 0.049
nucleoside metabolic process GO:0009116 394 0.048
cellular carbohydrate metabolic process GO:0044262 135 0.048
regulation of phosphorus metabolic process GO:0051174 230 0.048
phospholipid metabolic process GO:0006644 125 0.048
regulation of catabolic process GO:0009894 199 0.048
response to nutrient levels GO:0031667 150 0.047
glycosyl compound catabolic process GO:1901658 335 0.047
purine ribonucleotide metabolic process GO:0009150 372 0.047
mrna metabolic process GO:0016071 269 0.047
purine nucleoside monophosphate metabolic process GO:0009126 262 0.046
anatomical structure homeostasis GO:0060249 74 0.046
nucleobase containing compound catabolic process GO:0034655 479 0.045
purine containing compound catabolic process GO:0072523 332 0.045
vesicle mediated transport GO:0016192 335 0.044
purine nucleoside metabolic process GO:0042278 380 0.043
regulation of nucleoside metabolic process GO:0009118 106 0.043
single organism carbohydrate metabolic process GO:0044723 237 0.042
regulation of protein localization GO:0032880 62 0.041
negative regulation of gene expression epigenetic GO:0045814 147 0.041
purine nucleoside triphosphate catabolic process GO:0009146 329 0.040
regulation of cellular catabolic process GO:0031329 195 0.040
cellular nitrogen compound catabolic process GO:0044270 494 0.040
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.039
organophosphate catabolic process GO:0046434 338 0.037
purine containing compound metabolic process GO:0072521 400 0.037
negative regulation of molecular function GO:0044092 68 0.037
regulation of biological quality GO:0065008 391 0.037
protein modification by small protein conjugation or removal GO:0070647 172 0.036
cellular response to pheromone GO:0071444 88 0.035
ribonucleoside monophosphate catabolic process GO:0009158 224 0.034
cellular lipid metabolic process GO:0044255 229 0.034
cell cycle checkpoint GO:0000075 82 0.033
chromatin silencing at telomere GO:0006348 84 0.033
response to inorganic substance GO:0010035 47 0.033
atp catabolic process GO:0006200 224 0.033
ascospore wall assembly GO:0030476 52 0.033
regulation of hydrolase activity GO:0051336 133 0.032
lipid metabolic process GO:0006629 269 0.032
response to abiotic stimulus GO:0009628 159 0.031
carbohydrate derivative catabolic process GO:1901136 339 0.031
posttranscriptional regulation of gene expression GO:0010608 115 0.031
amide transport GO:0042886 22 0.030
nucleoside monophosphate catabolic process GO:0009125 224 0.030
positive regulation of nucleoside metabolic process GO:0045979 97 0.030
positive regulation of secretion GO:0051047 2 0.030
maintenance of protein location in cell GO:0032507 50 0.029
positive regulation of nucleotide metabolic process GO:0045981 101 0.029
mitotic cell cycle GO:0000278 306 0.029
ribonucleoprotein complex assembly GO:0022618 143 0.028
positive regulation of phosphorus metabolic process GO:0010562 147 0.028
conjugation with cellular fusion GO:0000747 106 0.028
nuclear division GO:0000280 263 0.028
meiotic nuclear division GO:0007126 163 0.027
purine nucleoside catabolic process GO:0006152 330 0.027
internal peptidyl lysine acetylation GO:0018393 52 0.027
cellular carbohydrate biosynthetic process GO:0034637 49 0.026
cell cycle dna replication GO:0044786 36 0.026
positive regulation of molecular function GO:0044093 185 0.026
cellular macromolecule catabolic process GO:0044265 363 0.026
monosaccharide metabolic process GO:0005996 83 0.026
negative regulation of cellular component organization GO:0051129 109 0.026
organonitrogen compound catabolic process GO:1901565 404 0.025
regulation of cell cycle GO:0051726 195 0.025
maintenance of protein location GO:0045185 53 0.025
regulation of translation GO:0006417 89 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
carbohydrate biosynthetic process GO:0016051 82 0.025
monocarboxylic acid transport GO:0015718 24 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.024
fungal type cell wall assembly GO:0071940 53 0.024
dephosphorylation GO:0016311 127 0.024
intracellular signal transduction GO:0035556 112 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.024
cell fate commitment GO:0045165 32 0.023
protein localization to organelle GO:0033365 337 0.023
ribonucleoside metabolic process GO:0009119 389 0.023
protein polyubiquitination GO:0000209 20 0.023
positive regulation of intracellular transport GO:0032388 4 0.023
cellular divalent inorganic cation homeostasis GO:0072503 21 0.023
regulation of gene expression epigenetic GO:0040029 147 0.023
divalent inorganic cation homeostasis GO:0072507 21 0.022
plasma membrane organization GO:0007009 21 0.022
single organism membrane fusion GO:0044801 71 0.022
positive regulation of rna biosynthetic process GO:1902680 286 0.022
atp metabolic process GO:0046034 251 0.022
response to oxygen containing compound GO:1901700 61 0.022
establishment of organelle localization GO:0051656 96 0.021
membrane invagination GO:0010324 43 0.021
regulation of nucleotide metabolic process GO:0006140 110 0.021
multi organism cellular process GO:0044764 120 0.021
negative regulation of phosphorylation GO:0042326 28 0.021
glycerophospholipid metabolic process GO:0006650 98 0.021
positive regulation of intracellular protein transport GO:0090316 3 0.020
positive regulation of apoptotic process GO:0043065 3 0.020
alpha amino acid biosynthetic process GO:1901607 91 0.020
regulation of protein metabolic process GO:0051246 237 0.020
endomembrane system organization GO:0010256 74 0.020
cell surface receptor signaling pathway GO:0007166 38 0.020
regulation of purine nucleotide catabolic process GO:0033121 106 0.020
secretion by cell GO:0032940 50 0.020
fungal type cell wall biogenesis GO:0009272 80 0.019
positive regulation of cellular biosynthetic process GO:0031328 336 0.019
cellular modified amino acid metabolic process GO:0006575 51 0.019
peptide transport GO:0015833 14 0.019
nitrogen compound transport GO:0071705 212 0.019
positive regulation of hydrolase activity GO:0051345 112 0.019
polysaccharide biosynthetic process GO:0000271 39 0.018
response to organic substance GO:0010033 182 0.018
mitochondrial genome maintenance GO:0000002 40 0.018
organelle fusion GO:0048284 85 0.018
mitotic cell cycle process GO:1903047 294 0.018
regulation of cellular component biogenesis GO:0044087 112 0.018
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.018
positive regulation of exocytosis GO:0045921 2 0.017
protein modification by small protein conjugation GO:0032446 144 0.017
regulation of purine nucleotide metabolic process GO:1900542 109 0.017
negative regulation of cell cycle GO:0045786 91 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.017
positive regulation of programmed cell death GO:0043068 3 0.017
cellular respiration GO:0045333 82 0.017
spore wall assembly GO:0042244 52 0.016
single organism membrane invagination GO:1902534 43 0.016
nucleocytoplasmic transport GO:0006913 163 0.016
energy reserve metabolic process GO:0006112 32 0.016
sulfur compound metabolic process GO:0006790 95 0.016
dna dependent dna replication GO:0006261 115 0.016
establishment of protein localization to membrane GO:0090150 99 0.016
ras protein signal transduction GO:0007265 29 0.016
rna catabolic process GO:0006401 118 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
growth GO:0040007 157 0.015
maintenance of location GO:0051235 66 0.015
protein localization to vacuole GO:0072665 92 0.015
cell growth GO:0016049 89 0.015
positive regulation of cellular protein metabolic process GO:0032270 89 0.015
cellular response to abiotic stimulus GO:0071214 62 0.015
peroxisome degradation GO:0030242 22 0.015
response to metal ion GO:0010038 24 0.015
response to acid chemical GO:0001101 19 0.015
ascospore wall biogenesis GO:0070591 52 0.015
positive regulation of secretion by cell GO:1903532 2 0.015
regulation of cell cycle process GO:0010564 150 0.014
membrane fusion GO:0061025 73 0.014
purine nucleotide biosynthetic process GO:0006164 41 0.014
transmembrane transport GO:0055085 349 0.014
g2 m transition of mitotic cell cycle GO:0000086 38 0.014
internal protein amino acid acetylation GO:0006475 52 0.014
peroxisome organization GO:0007031 68 0.014
protein complex localization GO:0031503 32 0.014
protein localization to membrane GO:0072657 102 0.014
negative regulation of phosphate metabolic process GO:0045936 49 0.014
positive regulation of gtp catabolic process GO:0033126 80 0.014
positive regulation of cytoplasmic transport GO:1903651 4 0.014
cellular response to oxygen containing compound GO:1901701 43 0.013
protein ubiquitination GO:0016567 118 0.013
cellular glucan metabolic process GO:0006073 44 0.013
cellular response to extracellular stimulus GO:0031668 150 0.013
actin filament based process GO:0030029 104 0.013
response to calcium ion GO:0051592 1 0.013
carbon catabolite regulation of transcription GO:0045990 39 0.013
aerobic respiration GO:0009060 55 0.013
divalent inorganic cation transport GO:0072511 26 0.013
protein localization to nucleus GO:0034504 74 0.013
ribose phosphate biosynthetic process GO:0046390 50 0.013
negative regulation of protein kinase activity GO:0006469 23 0.013
regulation of intracellular transport GO:0032386 26 0.013
negative regulation of catalytic activity GO:0043086 60 0.013
signal transduction by phosphorylation GO:0023014 31 0.012
regulation of organelle organization GO:0033043 243 0.012
regulation of dna replication GO:0006275 51 0.012
glycerolipid metabolic process GO:0046486 108 0.012
cellular ketone metabolic process GO:0042180 63 0.012
gtp catabolic process GO:0006184 107 0.012
positive regulation of biosynthetic process GO:0009891 336 0.012
single organism nuclear import GO:1902593 56 0.012
positive regulation of cell death GO:0010942 3 0.012
amine metabolic process GO:0009308 51 0.012
cytokinesis GO:0000910 92 0.012
piecemeal microautophagy of nucleus GO:0034727 33 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.012
autophagic vacuole assembly GO:0000045 16 0.012
regulation of ras gtpase activity GO:0032318 41 0.011
response to hypoxia GO:0001666 4 0.011
organelle fission GO:0048285 272 0.011
golgi to plasma membrane transport GO:0006893 33 0.011
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 44 0.011
cellular amine metabolic process GO:0044106 51 0.011
cell division GO:0051301 205 0.011
regulation of vesicle mediated transport GO:0060627 39 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.011
response to salt stress GO:0009651 34 0.011
phosphorylation GO:0016310 291 0.011
guanosine containing compound catabolic process GO:1901069 109 0.011
regulation of cellular response to stress GO:0080135 50 0.011
cellular response to hypoxia GO:0071456 4 0.011
regulation of dna metabolic process GO:0051052 100 0.011
hexose metabolic process GO:0019318 78 0.011
phospholipid dephosphorylation GO:0046839 15 0.011
positive regulation of phosphate metabolic process GO:0045937 147 0.011
organic hydroxy compound biosynthetic process GO:1901617 81 0.011
filamentous growth of a population of unicellular organisms GO:0044182 109 0.011
positive regulation of ras gtpase activity GO:0032320 41 0.011
negative regulation of cell communication GO:0010648 33 0.011
positive regulation of cellular component organization GO:0051130 116 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.010
dna templated transcription elongation GO:0006354 91 0.010
positive regulation of gtpase activity GO:0043547 80 0.010
gtp metabolic process GO:0046039 107 0.010
organic hydroxy compound metabolic process GO:1901615 125 0.010
microautophagy GO:0016237 43 0.010
endosomal transport GO:0016197 86 0.010
gene silencing by rna GO:0031047 3 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.010
dna integrity checkpoint GO:0031570 41 0.010
protein catabolic process GO:0030163 221 0.010

VPS13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025