Saccharomyces cerevisiae

65 known processes

PEP3 (YLR148W)

Pep3p

(Aliases: VAM8,VPT18,VPS18)

PEP3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of vesicle fusion GO:0031338 10 0.992
vacuole fusion non autophagic GO:0042144 40 0.982
snare complex assembly GO:0035493 10 0.973
regulation of vacuole fusion non autophagic GO:0032889 14 0.971
post golgi vesicle mediated transport GO:0006892 72 0.966
vesicle fusion GO:0006906 33 0.957
vacuole fusion GO:0097576 40 0.947
vesicle organization GO:0016050 68 0.947
regulation of snare complex assembly GO:0035542 9 0.927
regulation of vacuole organization GO:0044088 20 0.921
establishment of protein localization GO:0045184 367 0.892
Fly
vacuolar transport GO:0007034 145 0.877
establishment of protein localization to organelle GO:0072594 278 0.862
Fly
membrane fusion GO:0061025 73 0.830
organelle fusion GO:0048284 85 0.825
single organism membrane fusion GO:0044801 71 0.785
golgi to endosome transport GO:0006895 17 0.727
vacuole organization GO:0007033 75 0.714
cellular protein complex assembly GO:0043623 209 0.709
single organism cellular localization GO:1902580 375 0.677
Fly
golgi vesicle transport GO:0048193 188 0.635
protein targeting to vacuole GO:0006623 91 0.621
Fly
endosomal transport GO:0016197 86 0.620
protein transport GO:0015031 345 0.614
Fly
protein complex biogenesis GO:0070271 314 0.596
establishment of protein localization to vacuole GO:0072666 91 0.562
Fly
single organism membrane organization GO:0044802 275 0.553
golgi to vacuole transport GO:0006896 23 0.534
protein complex assembly GO:0006461 302 0.507
single organism membrane invagination GO:1902534 43 0.482
vesicle mediated transport GO:0016192 335 0.471
membrane organization GO:0061024 276 0.441
protein localization to vacuole GO:0072665 92 0.436
Fly
regulation of organelle organization GO:0033043 243 0.435
protein targeting GO:0006605 272 0.429
Fly
late endosome to vacuole transport GO:0045324 42 0.427
regulation of localization GO:0032879 127 0.420
regulation of protein complex assembly GO:0043254 77 0.393
regulation of vesicle mediated transport GO:0060627 39 0.337
piecemeal microautophagy of nucleus GO:0034727 33 0.313
intracellular protein transport GO:0006886 319 0.289
Fly
cellular macromolecule catabolic process GO:0044265 363 0.283
chromatin organization GO:0006325 242 0.267
regulation of transport GO:0051049 85 0.261
protein localization to organelle GO:0033365 337 0.203
Fly
macromolecule catabolic process GO:0009057 383 0.191
covalent chromatin modification GO:0016569 119 0.183
cellular protein catabolic process GO:0044257 213 0.183
protein catabolic process GO:0030163 221 0.164
regulation of cellular component organization GO:0051128 334 0.160
single organism catabolic process GO:0044712 619 0.154
Fly
organophosphate biosynthetic process GO:0090407 182 0.146
purine ribonucleoside metabolic process GO:0046128 380 0.144
nucleobase containing small molecule metabolic process GO:0055086 491 0.144
ribonucleoside metabolic process GO:0009119 389 0.137
organelle inheritance GO:0048308 51 0.127
regulation of cellular component biogenesis GO:0044087 112 0.126
nuclear division GO:0000280 263 0.117
microautophagy GO:0016237 43 0.109
organophosphate metabolic process GO:0019637 597 0.105
nucleotide metabolic process GO:0009117 453 0.103
purine containing compound metabolic process GO:0072521 400 0.098
membrane invagination GO:0010324 43 0.095
positive regulation of transport GO:0051050 32 0.091
protein modification by small protein conjugation or removal GO:0070647 172 0.088
membrane docking GO:0022406 22 0.085
autophagy GO:0006914 106 0.083
Fly
glycosyl compound metabolic process GO:1901657 398 0.081
ribose phosphate metabolic process GO:0019693 384 0.078
purine nucleoside metabolic process GO:0042278 380 0.074
nucleoside triphosphate metabolic process GO:0009141 364 0.073
nucleoside metabolic process GO:0009116 394 0.072
nucleocytoplasmic transport GO:0006913 163 0.072
vesicle docking GO:0048278 16 0.071
nucleophagy GO:0044804 34 0.070
homeostatic process GO:0042592 227 0.068
nucleoside phosphate metabolic process GO:0006753 458 0.068
regulation of phosphate metabolic process GO:0019220 230 0.065
histone ubiquitination GO:0016574 17 0.065
protein modification by small protein conjugation GO:0032446 144 0.065
establishment of cell polarity GO:0030010 64 0.059
ribosomal small subunit biogenesis GO:0042274 124 0.057
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.056
nuclear export GO:0051168 124 0.055
secretion GO:0046903 50 0.054
regulation of cellular localization GO:0060341 50 0.053
rna localization GO:0006403 112 0.053
negative regulation of organelle organization GO:0010639 103 0.053
dna recombination GO:0006310 172 0.050
late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511 26 0.050
mitochondrion organization GO:0007005 261 0.050
glycosyl compound catabolic process GO:1901658 335 0.049
regulation of protein localization GO:0032880 62 0.047
purine ribonucleotide metabolic process GO:0009150 372 0.047
ion homeostasis GO:0050801 118 0.046
transcription from rna polymerase i promoter GO:0006360 63 0.044
regulation of phosphorus metabolic process GO:0051174 230 0.043
nuclear transport GO:0051169 165 0.042
gtp metabolic process GO:0046039 107 0.042
nucleoside triphosphate catabolic process GO:0009143 329 0.042
double strand break repair GO:0006302 105 0.040
macromolecular complex disassembly GO:0032984 80 0.040
sphingolipid metabolic process GO:0006665 41 0.040
purine nucleotide metabolic process GO:0006163 376 0.039
purine nucleoside triphosphate catabolic process GO:0009146 329 0.039
positive regulation of cytoplasmic transport GO:1903651 4 0.038
ribonucleoside triphosphate metabolic process GO:0009199 356 0.038
early endosome to late endosome transport GO:0045022 1 0.038
nucleobase containing compound catabolic process GO:0034655 479 0.038
nucleic acid transport GO:0050657 94 0.037
chromosome segregation GO:0007059 159 0.037
ribonucleoside triphosphate catabolic process GO:0009203 327 0.037
monovalent inorganic cation transport GO:0015672 78 0.036
positive regulation of cellular component organization GO:0051130 116 0.036
chemical homeostasis GO:0048878 137 0.036
carbohydrate derivative metabolic process GO:1901135 549 0.035
cellular nitrogen compound catabolic process GO:0044270 494 0.035
growth GO:0040007 157 0.035
cellular response to extracellular stimulus GO:0031668 150 0.035
Fly
negative regulation of cell cycle process GO:0010948 86 0.034
transmembrane transport GO:0055085 349 0.033
secretion by cell GO:0032940 50 0.033
programmed cell death GO:0012501 30 0.033
organic hydroxy compound metabolic process GO:1901615 125 0.033
regulation of cellular ph GO:0030641 17 0.033
ribonucleoprotein complex subunit organization GO:0071826 152 0.032
purine ribonucleoside catabolic process GO:0046130 330 0.031
regulation of cytoskeleton organization GO:0051493 63 0.031
spindle organization GO:0007051 37 0.031
cation transmembrane transport GO:0098655 135 0.030
endosome transport via multivesicular body sorting pathway GO:0032509 27 0.030
intracellular protein transmembrane transport GO:0065002 80 0.030
organelle assembly GO:0070925 118 0.030
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.030
ph reduction GO:0045851 16 0.030
cell wall biogenesis GO:0042546 93 0.029
cytoskeleton organization GO:0007010 230 0.029
cation transport GO:0006812 166 0.029
mitotic recombination GO:0006312 55 0.029
organic cyclic compound catabolic process GO:1901361 499 0.029
organonitrogen compound catabolic process GO:1901565 404 0.029
cellular homeostasis GO:0019725 138 0.029
cellular ion homeostasis GO:0006873 112 0.028
protein processing GO:0016485 64 0.028
regulation of nucleotide catabolic process GO:0030811 106 0.028
single organism signaling GO:0044700 208 0.028
Fly
ribonucleoside catabolic process GO:0042454 332 0.028
developmental process GO:0032502 261 0.028
Fly
ion transport GO:0006811 274 0.028
positive regulation of intracellular transport GO:0032388 4 0.027
rna transport GO:0050658 92 0.027
invasive filamentous growth GO:0036267 65 0.027
protein ubiquitination GO:0016567 118 0.027
organelle fission GO:0048285 272 0.027
negative regulation of gene expression epigenetic GO:0045814 147 0.026
monovalent inorganic cation homeostasis GO:0055067 32 0.026
mitotic nuclear division GO:0007067 131 0.026
cvt pathway GO:0032258 37 0.026
spindle checkpoint GO:0031577 35 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.025
response to pheromone GO:0019236 92 0.025
establishment of rna localization GO:0051236 92 0.025
purine nucleoside monophosphate metabolic process GO:0009126 262 0.025
double strand break repair via homologous recombination GO:0000724 54 0.025
purine containing compound catabolic process GO:0072523 332 0.025
ribosome biogenesis GO:0042254 335 0.025
response to chemical GO:0042221 390 0.024
exit from mitosis GO:0010458 37 0.024
reproductive process GO:0022414 248 0.024
Fly
nucleoside phosphate biosynthetic process GO:1901293 80 0.024
intra golgi vesicle mediated transport GO:0006891 22 0.024
endocytosis GO:0006897 90 0.024
Fly
ribonucleotide catabolic process GO:0009261 327 0.024
protein maturation GO:0051604 76 0.024
positive regulation of nucleotide metabolic process GO:0045981 101 0.023
purine nucleotide biosynthetic process GO:0006164 41 0.023
lipid metabolic process GO:0006629 269 0.023
protein alkylation GO:0008213 48 0.023
ribonucleotide metabolic process GO:0009259 377 0.022
regulation of chromosome organization GO:0033044 66 0.022
n terminal protein amino acid modification GO:0031365 9 0.022
nucleoside biosynthetic process GO:0009163 38 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.022
negative regulation of nucleic acid templated transcription GO:1903507 260 0.022
heterocycle catabolic process GO:0046700 494 0.022
cellular chemical homeostasis GO:0055082 123 0.021
regulation of purine nucleotide metabolic process GO:1900542 109 0.021
cation homeostasis GO:0055080 105 0.021
positive regulation of hydrolase activity GO:0051345 112 0.021
organic acid metabolic process GO:0006082 352 0.021
steroid metabolic process GO:0008202 47 0.021
regulation of nuclear division GO:0051783 103 0.021
mitotic cell cycle process GO:1903047 294 0.021
single organism nuclear import GO:1902593 56 0.021
phosphorylation GO:0016310 291 0.021
single organism developmental process GO:0044767 258 0.021
Fly
response to temperature stimulus GO:0009266 74 0.021
positive regulation of molecular function GO:0044093 185 0.021
positive regulation of secretion by cell GO:1903532 2 0.021
regulation of cellular amine metabolic process GO:0033238 21 0.021
carbohydrate derivative catabolic process GO:1901136 339 0.021
nucleoside monophosphate metabolic process GO:0009123 267 0.020
maintenance of location in cell GO:0051651 58 0.020
sulfur compound metabolic process GO:0006790 95 0.020
response to abiotic stimulus GO:0009628 159 0.020
purine nucleoside biosynthetic process GO:0042451 31 0.020
organic acid biosynthetic process GO:0016053 152 0.020
nucleoside phosphate catabolic process GO:1901292 331 0.020
positive regulation of organelle organization GO:0010638 85 0.020
death GO:0016265 30 0.020
regulation of molecular function GO:0065009 320 0.020
gene silencing GO:0016458 151 0.020
cell death GO:0008219 30 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.020
apoptotic process GO:0006915 30 0.019
mitotic cell cycle GO:0000278 306 0.019
meiotic nuclear division GO:0007126 163 0.019
proteolysis GO:0006508 268 0.019
cytokinesis site selection GO:0007105 40 0.019
sporulation resulting in formation of a cellular spore GO:0030435 129 0.019
endomembrane system organization GO:0010256 74 0.019
Human Fly
amine metabolic process GO:0009308 51 0.019
chromatin silencing GO:0006342 147 0.019
regulation of cellular component size GO:0032535 50 0.019
chromatin remodeling GO:0006338 80 0.018
protein acylation GO:0043543 66 0.018
fungal type cell wall organization GO:0031505 145 0.018
purine ribonucleotide catabolic process GO:0009154 327 0.018
glycerophospholipid metabolic process GO:0006650 98 0.018
vacuole inheritance GO:0000011 16 0.018
regulation of catalytic activity GO:0050790 307 0.018
aromatic compound catabolic process GO:0019439 491 0.017
autophagic vacuole assembly GO:0000045 16 0.017
negative regulation of phosphate metabolic process GO:0045936 49 0.017
small molecule catabolic process GO:0044282 88 0.017
fungal type cell wall biogenesis GO:0009272 80 0.017
negative regulation of nuclear division GO:0051784 62 0.017
chromatin silencing at silent mating type cassette GO:0030466 53 0.017
negative regulation of dna metabolic process GO:0051053 36 0.017
reproduction of a single celled organism GO:0032505 191 0.017
regulation of chromatin organization GO:1902275 23 0.017
positive regulation of protein complex assembly GO:0031334 39 0.017
nuclear transcribed mrna catabolic process GO:0000956 89 0.017
purine nucleotide catabolic process GO:0006195 328 0.017
regulation of cellular amino acid metabolic process GO:0006521 16 0.017
purine nucleoside catabolic process GO:0006152 330 0.016
reciprocal dna recombination GO:0035825 54 0.016
response to osmotic stress GO:0006970 83 0.016
cellular response to chemical stimulus GO:0070887 315 0.016
protein depolymerization GO:0051261 21 0.016
negative regulation of transcription dna templated GO:0045892 258 0.016
cell wall organization or biogenesis GO:0071554 190 0.016
organonitrogen compound biosynthetic process GO:1901566 314 0.016
Fly
cellular response to organic substance GO:0071310 159 0.016
ribonucleoside biosynthetic process GO:0042455 37 0.016
sexual reproduction GO:0019953 216 0.016
Fly
glycogen metabolic process GO:0005977 30 0.016
cellular bud site selection GO:0000282 35 0.016
cellular cation homeostasis GO:0030003 100 0.016
negative regulation of phosphorylation GO:0042326 28 0.016
protein import GO:0017038 122 0.016
regulation of cell cycle phase transition GO:1901987 70 0.016
positive regulation of protein metabolic process GO:0051247 93 0.015
protein transmembrane transport GO:0071806 82 0.015
transcription from rna polymerase iii promoter GO:0006383 40 0.015
cellular response to starvation GO:0009267 90 0.015
Fly
positive regulation of secretion GO:0051047 2 0.015
regulation of ph GO:0006885 21 0.015
regulation of response to stimulus GO:0048583 157 0.015
Fly
peptidyl amino acid modification GO:0018193 116 0.015
cellular alcohol metabolic process GO:0044107 34 0.015
cellular component disassembly GO:0022411 86 0.015
positive regulation of phosphorus metabolic process GO:0010562 147 0.015
multi organism cellular process GO:0044764 120 0.015
mitotic cytokinesis site selection GO:1902408 35 0.015
alcohol metabolic process GO:0006066 112 0.014
single organism carbohydrate metabolic process GO:0044723 237 0.014
protein localization to nucleus GO:0034504 74 0.014
regulation of dna metabolic process GO:0051052 100 0.014
regulation of biological quality GO:0065008 391 0.014
organelle localization GO:0051640 128 0.014
ascospore wall biogenesis GO:0070591 52 0.014
ion transmembrane transport GO:0034220 200 0.014
regulation of hydrolase activity GO:0051336 133 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
telomere maintenance via recombination GO:0000722 32 0.014
positive regulation of gtpase activity GO:0043547 80 0.014
regulation of establishment of protein localization GO:0070201 17 0.014
intracellular protein transmembrane import GO:0044743 67 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.014
organophosphate catabolic process GO:0046434 338 0.014
gene silencing by rna GO:0031047 3 0.014
nucleotide catabolic process GO:0009166 330 0.014
cell wall assembly GO:0070726 54 0.013
regulation of mitosis GO:0007088 65 0.013
recombinational repair GO:0000725 64 0.013
cell growth GO:0016049 89 0.013
regulation of cell division GO:0051302 113 0.013
liposaccharide metabolic process GO:1903509 31 0.013
maintenance of protein location GO:0045185 53 0.013
phospholipid metabolic process GO:0006644 125 0.013
membrane lipid metabolic process GO:0006643 67 0.013
mrna metabolic process GO:0016071 269 0.013
response to organic cyclic compound GO:0014070 1 0.013
mitotic cytokinesis GO:0000281 58 0.013
double strand break repair via nonhomologous end joining GO:0006303 27 0.013
protein phosphorylation GO:0006468 197 0.013
ribonucleoside monophosphate metabolic process GO:0009161 265 0.013
regulation of intracellular transport GO:0032386 26 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.013
mitochondrion inheritance GO:0000001 21 0.013
rna 3 end processing GO:0031123 88 0.013
regulation of protein localization to nucleus GO:1900180 16 0.013
cellular carbohydrate metabolic process GO:0044262 135 0.013
septin ring organization GO:0031106 26 0.012
nucleoside catabolic process GO:0009164 335 0.012
cellular lipid metabolic process GO:0044255 229 0.012
regulation of actin filament based process GO:0032970 31 0.012
glycolipid metabolic process GO:0006664 31 0.012
cellular polysaccharide metabolic process GO:0044264 55 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.012
regulation of cell cycle GO:0051726 195 0.012
intracellular ph reduction GO:0051452 16 0.012
negative regulation of cell division GO:0051782 66 0.012
dna repair GO:0006281 236 0.012
positive regulation of nucleoside metabolic process GO:0045979 97 0.012
glycerophospholipid biosynthetic process GO:0046474 68 0.012
ras protein signal transduction GO:0007265 29 0.012
response to extracellular stimulus GO:0009991 156 0.012
Fly
negative regulation of ergosterol biosynthetic process GO:0010895 1 0.012
cellular response to abiotic stimulus GO:0071214 62 0.012
organic hydroxy compound transport GO:0015850 41 0.012
negative regulation of rna biosynthetic process GO:1902679 260 0.012
cellular amino acid metabolic process GO:0006520 225 0.012
multi organism process GO:0051704 233 0.012
Fly
response to external stimulus GO:0009605 158 0.012
Fly
nuclear import GO:0051170 57 0.012
cell division GO:0051301 205 0.011
Fly
regulation of cellular response to drug GO:2001038 3 0.011
positive regulation of apoptotic process GO:0043065 3 0.011
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.011
protein polymerization GO:0051258 51 0.011
signaling GO:0023052 208 0.011
Fly
regulation of cellular protein metabolic process GO:0032268 232 0.011
regulation of mitotic cell cycle GO:0007346 107 0.011
chromatin silencing at rdna GO:0000183 32 0.011
regulation of response to stress GO:0080134 57 0.011
inorganic ion transmembrane transport GO:0098660 109 0.011
positive regulation of cellular protein metabolic process GO:0032270 89 0.011
plasma membrane organization GO:0007009 21 0.011
maintenance of protein location in cell GO:0032507 50 0.010
phospholipid biosynthetic process GO:0008654 89 0.010
chromatin modification GO:0016568 200 0.010
cellular response to external stimulus GO:0071496 150 0.010
Fly
chronological cell aging GO:0001300 28 0.010
g1 s transition of mitotic cell cycle GO:0000082 64 0.010
mrna export from nucleus GO:0006406 60 0.010
response to calcium ion GO:0051592 1 0.010
cellular glucan metabolic process GO:0006073 44 0.010
regulation of actin cytoskeleton organization GO:0032956 31 0.010
nucleobase containing compound transport GO:0015931 124 0.010
mitochondrion localization GO:0051646 29 0.010
protein lipidation GO:0006497 40 0.010
carboxylic acid biosynthetic process GO:0046394 152 0.010
regulation of protein metabolic process GO:0051246 237 0.010
histone modification GO:0016570 119 0.010
spore wall biogenesis GO:0070590 52 0.010

PEP3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.018