Saccharomyces cerevisiae

69 known processes

SIS1 (YNL007C)

Sis1p

SIS1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein refolding GO:0042026 16 0.997
Human
protein folding GO:0006457 94 0.988
protein targeting to er GO:0045047 39 0.954
intracellular protein transmembrane transport GO:0065002 80 0.752
protein localization to nucleus GO:0034504 74 0.719
establishment of protein localization to endoplasmic reticulum GO:0072599 40 0.685
mitochondrion organization GO:0007005 261 0.668
mitochondrial transport GO:0006839 76 0.611
inclusion body assembly GO:0070841 1 0.564
Human
transmembrane transport GO:0055085 349 0.563
protein localization to mitochondrion GO:0070585 63 0.459
protein import GO:0017038 122 0.424
establishment of protein localization GO:0045184 367 0.405
establishment of protein localization to mitochondrion GO:0072655 63 0.404
protein transport GO:0015031 345 0.403
ribonucleoside triphosphate metabolic process GO:0009199 356 0.385
Human
intracellular protein transmembrane import GO:0044743 67 0.380
intracellular protein transport GO:0006886 319 0.377
regulation of cellular component biogenesis GO:0044087 112 0.359
Human
regulation of protein modification process GO:0031399 110 0.353
protein targeting to mitochondrion GO:0006626 56 0.345
ribonucleotide metabolic process GO:0009259 377 0.332
Human
nucleotide catabolic process GO:0009166 330 0.324
Human
protein transmembrane transport GO:0071806 82 0.307
protein localization to organelle GO:0033365 337 0.306
chaperone mediated protein folding GO:0061077 3 0.300
Human Mouse
nucleoside metabolic process GO:0009116 394 0.296
Human
organophosphate catabolic process GO:0046434 338 0.282
Human
single organism cellular localization GO:1902580 375 0.258
protein phosphorylation GO:0006468 197 0.257
purine containing compound metabolic process GO:0072521 400 0.251
Human
nucleobase containing compound catabolic process GO:0034655 479 0.248
Human
purine containing compound catabolic process GO:0072523 332 0.244
Human
negative regulation of cellular protein metabolic process GO:0032269 85 0.226
ribonucleoside metabolic process GO:0009119 389 0.220
Human
response to chemical GO:0042221 390 0.213
srp dependent cotranslational protein targeting to membrane translocation GO:0006616 9 0.210
positive regulation of macromolecule metabolic process GO:0010604 394 0.198
carbohydrate derivative metabolic process GO:1901135 549 0.193
Human
negative regulation of protein metabolic process GO:0051248 85 0.192
purine nucleoside metabolic process GO:0042278 380 0.190
Human
ion transport GO:0006811 274 0.190
response to heat GO:0009408 69 0.190
Fly
regulation of phosphate metabolic process GO:0019220 230 0.173
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.172
Human
protein modification by small protein conjugation GO:0032446 144 0.168
ribonucleoside catabolic process GO:0042454 332 0.165
Human
nucleoside triphosphate catabolic process GO:0009143 329 0.161
Human
response to topologically incorrect protein GO:0035966 38 0.160
regulation of cellular component organization GO:0051128 334 0.159
Human
nucleotide metabolic process GO:0009117 453 0.156
Human
aromatic compound catabolic process GO:0019439 491 0.154
Human
rrna metabolic process GO:0016072 244 0.151
purine nucleotide metabolic process GO:0006163 376 0.151
Human
purine ribonucleotide metabolic process GO:0009150 372 0.151
Human
glycosyl compound metabolic process GO:1901657 398 0.150
Human
purine nucleoside triphosphate catabolic process GO:0009146 329 0.147
Human
vesicle mediated transport GO:0016192 335 0.141
rna splicing via transesterification reactions GO:0000375 118 0.139
misfolded or incompletely synthesized protein catabolic process GO:0006515 21 0.139
mrna catabolic process GO:0006402 93 0.135
purine nucleotide catabolic process GO:0006195 328 0.134
Human
response to organic substance GO:0010033 182 0.132
regulation of phosphorus metabolic process GO:0051174 230 0.127
Human
carbohydrate derivative catabolic process GO:1901136 339 0.127
Human
glycosyl compound catabolic process GO:1901658 335 0.127
Human
establishment of protein localization to organelle GO:0072594 278 0.125
regulation of protein phosphorylation GO:0001932 75 0.123
regulation of cell growth GO:0001558 29 0.123
cellular response to organic substance GO:0071310 159 0.123
ribosomal subunit export from nucleus GO:0000054 46 0.121
nucleoside catabolic process GO:0009164 335 0.120
Human
nucleoside phosphate metabolic process GO:0006753 458 0.119
Human
single organism signaling GO:0044700 208 0.119
regulation of biological quality GO:0065008 391 0.117
protein complex disassembly GO:0043241 70 0.113
macromolecule catabolic process GO:0009057 383 0.110
regulation of cellular protein metabolic process GO:0032268 232 0.107
protein complex biogenesis GO:0070271 314 0.103
purine ribonucleoside catabolic process GO:0046130 330 0.099
Human
response to nutrient levels GO:0031667 150 0.098
organonitrogen compound catabolic process GO:1901565 404 0.095
Human
cellular response to topologically incorrect protein GO:0035967 32 0.094
cellular response to extracellular stimulus GO:0031668 150 0.092
heterocycle catabolic process GO:0046700 494 0.091
Human
cellular response to heat GO:0034605 53 0.091
ribonucleoside triphosphate catabolic process GO:0009203 327 0.090
Human
establishment of ribosome localization GO:0033753 46 0.087
purine ribonucleoside metabolic process GO:0046128 380 0.087
Human
regulation of protein ubiquitination GO:0031396 20 0.086
regulation of catalytic activity GO:0050790 307 0.086
Human
signaling GO:0023052 208 0.086
purine ribonucleotide catabolic process GO:0009154 327 0.085
Human
purine nucleoside triphosphate metabolic process GO:0009144 356 0.084
Human
ribonucleoside monophosphate metabolic process GO:0009161 265 0.082
Human
purine nucleoside monophosphate catabolic process GO:0009128 224 0.082
Human
regulation of phosphorylation GO:0042325 86 0.081
positive regulation of protein modification process GO:0031401 49 0.079
single organism reproductive process GO:0044702 159 0.077
ribonucleoprotein complex subunit organization GO:0071826 152 0.077
rrna processing GO:0006364 227 0.076
response to temperature stimulus GO:0009266 74 0.073
Fly
organophosphate metabolic process GO:0019637 597 0.073
Human
mrna splicing via spliceosome GO:0000398 108 0.073
ribose phosphate metabolic process GO:0019693 384 0.072
Human
conjugation with cellular fusion GO:0000747 106 0.071
nucleoside phosphate catabolic process GO:1901292 331 0.071
Human
protein folding in endoplasmic reticulum GO:0034975 13 0.070
regulation of molecular function GO:0065009 320 0.068
Human
cellular nitrogen compound catabolic process GO:0044270 494 0.067
Human
protein ubiquitination GO:0016567 118 0.067
translation GO:0006412 230 0.067
regulation of signaling GO:0023051 119 0.066
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.065
protein targeting GO:0006605 272 0.064
protein localization to endoplasmic reticulum GO:0070972 47 0.064
cellular protein complex assembly GO:0043623 209 0.064
ribonucleoprotein complex assembly GO:0022618 143 0.063
protein modification by small protein conjugation or removal GO:0070647 172 0.063
srp dependent cotranslational protein targeting to membrane GO:0006614 14 0.061
ribonucleotide catabolic process GO:0009261 327 0.059
Human
cellular macromolecule catabolic process GO:0044265 363 0.059
negative regulation of macromolecule metabolic process GO:0010605 375 0.057
response to abiotic stimulus GO:0009628 159 0.056
Fly
protein depolymerization GO:0051261 21 0.054
cellular component disassembly GO:0022411 86 0.053
rna catabolic process GO:0006401 118 0.053
protein import into mitochondrial matrix GO:0030150 20 0.053
mrna metabolic process GO:0016071 269 0.053
regulation of translation GO:0006417 89 0.052
nitrogen compound transport GO:0071705 212 0.052
response to unfolded protein GO:0006986 29 0.051
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.051
Human
homeostatic process GO:0042592 227 0.051
negative regulation of cellular metabolic process GO:0031324 407 0.051
regulation of protein metabolic process GO:0051246 237 0.051
cellular response to starvation GO:0009267 90 0.049
regulation of cell communication GO:0010646 124 0.049
nucleobase containing small molecule metabolic process GO:0055086 491 0.048
Human
nucleoside triphosphate metabolic process GO:0009141 364 0.046
Human
ion homeostasis GO:0050801 118 0.046
cellular response to chemical stimulus GO:0070887 315 0.045
positive regulation of catalytic activity GO:0043085 178 0.045
Human
regulation of hydrolase activity GO:0051336 133 0.045
Human
sexual reproduction GO:0019953 216 0.044
positive regulation of molecular function GO:0044093 185 0.044
Human
chemical homeostasis GO:0048878 137 0.043
purine nucleoside monophosphate metabolic process GO:0009126 262 0.042
Human
negative regulation of protein modification process GO:0031400 37 0.042
purine nucleoside catabolic process GO:0006152 330 0.042
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.040
Human
macromolecular complex disassembly GO:0032984 80 0.039
de novo protein folding GO:0006458 10 0.039
Mouse
protein catabolic process GO:0030163 221 0.039
ribosome localization GO:0033750 46 0.039
nuclear transport GO:0051169 165 0.038
positive regulation of phosphate metabolic process GO:0045937 147 0.037
Human
positive regulation of hydrolase activity GO:0051345 112 0.036
Human
positive regulation of gene expression GO:0010628 321 0.036
cellular heat acclimation GO:0070370 1 0.036
posttranscriptional regulation of gene expression GO:0010608 115 0.036
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.035
Human
protein complex assembly GO:0006461 302 0.034
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.034
positive regulation of cellular protein metabolic process GO:0032270 89 0.034
protein localization to membrane GO:0072657 102 0.033
atp catabolic process GO:0006200 224 0.033
Human
mrna processing GO:0006397 185 0.033
ribonucleoprotein complex export from nucleus GO:0071426 46 0.033
cellular protein complex disassembly GO:0043624 42 0.033
response to extracellular stimulus GO:0009991 156 0.032
positive regulation of cellular component organization GO:0051130 116 0.032
cellular response to nutrient levels GO:0031669 144 0.031
negative regulation of protein kinase activity GO:0006469 23 0.031
reproductive process GO:0022414 248 0.030
nuclear export GO:0051168 124 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.030
Human
single organism nuclear import GO:1902593 56 0.030
chromosome segregation GO:0007059 159 0.029
ribonucleoprotein complex localization GO:0071166 46 0.029
positive regulation of mrna processing GO:0050685 3 0.029
cellular protein catabolic process GO:0044257 213 0.029
cation transport GO:0006812 166 0.028
organic cyclic compound catabolic process GO:1901361 499 0.028
Human
regulation of macroautophagy GO:0016241 15 0.028
regulation of translational elongation GO:0006448 25 0.028
regulation of transferase activity GO:0051338 83 0.028
single organism catabolic process GO:0044712 619 0.028
atp metabolic process GO:0046034 251 0.027
Human
protein targeting to membrane GO:0006612 52 0.027
protein import into nucleus GO:0006606 55 0.027
negative regulation of protein phosphorylation GO:0001933 24 0.026
regulation of mrna splicing via spliceosome GO:0048024 3 0.026
negative regulation of transcription dna templated GO:0045892 258 0.026
regulation of chromosome organization GO:0033044 66 0.026
cellular response to external stimulus GO:0071496 150 0.026
negative regulation of gene expression GO:0010629 312 0.026
rna splicing GO:0008380 131 0.025
ncrna processing GO:0034470 330 0.025
regulation of kinase activity GO:0043549 71 0.025
nucleoside monophosphate catabolic process GO:0009125 224 0.025
Human
ribonucleoside monophosphate catabolic process GO:0009158 224 0.025
Human
establishment of organelle localization GO:0051656 96 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.024
Human
growth GO:0040007 157 0.024
multi organism reproductive process GO:0044703 216 0.024
endosomal transport GO:0016197 86 0.024
gene silencing by rna GO:0031047 3 0.024
regulation of anatomical structure size GO:0090066 50 0.024
positive regulation of protein metabolic process GO:0051247 93 0.023
regulation of transport GO:0051049 85 0.023
protein targeting to nucleus GO:0044744 57 0.023
organelle disassembly GO:1903008 13 0.022
nuclear transcribed mrna catabolic process GO:0000956 89 0.022
cell communication GO:0007154 345 0.021
dna repair GO:0006281 236 0.020
positive regulation of phosphorylation GO:0042327 33 0.020
g2 m transition of mitotic cell cycle GO:0000086 38 0.020
secretion GO:0046903 50 0.019
positive regulation of transport GO:0051050 32 0.019
chaperone mediated protein complex assembly GO:0051131 6 0.019
organic anion transport GO:0015711 114 0.019
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.019
guanosine containing compound metabolic process GO:1901068 111 0.019
positive regulation of secretion by cell GO:1903532 2 0.019
positive regulation of organelle organization GO:0010638 85 0.019
ribonucleoprotein complex disassembly GO:0032988 11 0.019
response to organic cyclic compound GO:0014070 1 0.019
actin filament organization GO:0007015 56 0.019
negative regulation of proteolysis GO:0045861 33 0.018
cytoplasmic translation GO:0002181 65 0.018
positive regulation of cellular catabolic process GO:0031331 128 0.018
Human
nucleocytoplasmic transport GO:0006913 163 0.018
regulation of actin filament based process GO:0032970 31 0.018
positive regulation of mrna metabolic process GO:1903313 7 0.018
positive regulation of phosphorus metabolic process GO:0010562 147 0.018
Human
positive regulation of apoptotic process GO:0043065 3 0.018
regulation of protein maturation GO:1903317 34 0.017
negative regulation of cellular component organization GO:0051129 109 0.017
Human
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 46 0.017
regulation of response to stimulus GO:0048583 157 0.017
multi organism cellular process GO:0044764 120 0.017
nucleoside monophosphate metabolic process GO:0009123 267 0.017
Human
organelle localization GO:0051640 128 0.017
autophagy GO:0006914 106 0.017
positive regulation of cytoplasmic transport GO:1903651 4 0.017
regulation of rna splicing GO:0043484 3 0.017
positive regulation of protein complex assembly GO:0031334 39 0.017
negative regulation of cellular biosynthetic process GO:0031327 312 0.016
single organism developmental process GO:0044767 258 0.016
cellular chemical homeostasis GO:0055082 123 0.016
dephosphorylation GO:0016311 127 0.016
positive regulation of protein ubiquitination GO:0031398 7 0.015
cotranslational protein targeting to membrane GO:0006613 15 0.015
regulation of protein polymerization GO:0032271 33 0.015
positive regulation of cellular component biogenesis GO:0044089 45 0.015
negative regulation of rna biosynthetic process GO:1902679 260 0.014
negative regulation of catalytic activity GO:0043086 60 0.014
establishment of protein localization to mitochondrial membrane GO:0090151 20 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.014
positive regulation of catabolic process GO:0009896 135 0.014
Human
regulation of cellular amino acid metabolic process GO:0006521 16 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.013
nucleotide biosynthetic process GO:0009165 79 0.013
nucleoside phosphate biosynthetic process GO:1901293 80 0.013
regulation of nucleotide metabolic process GO:0006140 110 0.013
Human
regulation of cellular catabolic process GO:0031329 195 0.013
Human
positive regulation of rna splicing GO:0033120 2 0.013
meiosis i GO:0007127 92 0.013
regulation of intracellular signal transduction GO:1902531 78 0.012
positive regulation of mrna splicing via spliceosome GO:0048026 2 0.012
conjugation GO:0000746 107 0.012
gtp metabolic process GO:0046039 107 0.012
regulation of small gtpase mediated signal transduction GO:0051056 47 0.012
negative regulation of cell communication GO:0010648 33 0.012
positive regulation of cytoskeleton organization GO:0051495 39 0.012
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 44 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.012
cellular response to endogenous stimulus GO:0071495 22 0.012
glycosyl compound biosynthetic process GO:1901659 42 0.012
programmed cell death GO:0012501 30 0.011
maintenance of protein location GO:0045185 53 0.011
translational elongation GO:0006414 32 0.011
regulation of ph GO:0006885 21 0.011
positive regulation of biosynthetic process GO:0009891 336 0.011
gtp catabolic process GO:0006184 107 0.011
regulation of purine nucleotide metabolic process GO:1900542 109 0.011
Human
cell growth GO:0016049 89 0.011
positive regulation of intracellular transport GO:0032388 4 0.011
dna replication GO:0006260 147 0.011
signal transduction GO:0007165 208 0.010
positive regulation of programmed cell death GO:0043068 3 0.010
response to starvation GO:0042594 96 0.010
positive regulation of cellular biosynthetic process GO:0031328 336 0.010
translational termination GO:0006415 17 0.010
late endosome to vacuole transport GO:0045324 42 0.010
regulation of cellular component size GO:0032535 50 0.010
regulation of purine nucleotide catabolic process GO:0033121 106 0.010
Human
secretion by cell GO:0032940 50 0.010

SIS1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org