Drosophila melanogaster

47 known processes

I-2 (Dmel_CG10574)

Inhibitor-2

(Aliases: SET,I-2PP1,CG10574,Dmel\CG10574,Dm I-2,I-2Dm)

I-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic nuclear division GO:0007067 213 0.218
regulation of protein dephosphorylation GO:0035304 5 0.188
epithelial cell development GO:0002064 274 0.174
organelle fission GO:0048285 340 0.171
dephosphorylation GO:0016311 51 0.155
chromosome segregation GO:0007059 157 0.151
imaginal disc derived appendage morphogenesis GO:0035114 395 0.146
nuclear division GO:0000280 332 0.141
defense response to other organism GO:0098542 225 0.124
defense response GO:0006952 300 0.118
cell division GO:0051301 248 0.113
protein modification process GO:0036211 438 0.111
response to other organism GO:0051707 293 0.111
regulation of protein metabolic process GO:0051246 256 0.110
positive regulation of macromolecule metabolic process GO:0010604 405 0.107
regulation of phosphorus metabolic process GO:0051174 210 0.104
post embryonic appendage morphogenesis GO:0035120 385 0.103
regulation of cell cycle GO:0051726 291 0.097
chemotaxis GO:0006935 249 0.096
taxis GO:0042330 304 0.092
response to light stimulus GO:0009416 124 0.092
regulation of phosphate metabolic process GO:0019220 210 0.091
adult behavior GO:0030534 137 0.091
vesicle mediated transport GO:0016192 381 0.089
single organism catabolic process GO:0044712 228 0.089
neuron projection guidance GO:0097485 241 0.087
establishment of localization in cell GO:0051649 402 0.087
defense response to bacterium GO:0042742 178 0.086
multi multicellular organism process GO:0044706 123 0.083
axon development GO:0061564 297 0.083
catabolic process GO:0009056 409 0.082
axonogenesis GO:0007409 290 0.080
ovarian follicle cell development GO:0030707 248 0.080
endocytosis GO:0006897 310 0.079
adult locomotory behavior GO:0008344 76 0.077
response to biotic stimulus GO:0009607 294 0.077
establishment of organelle localization GO:0051656 122 0.075
cellular protein modification process GO:0006464 438 0.074
immune system process GO:0002376 347 0.073
organonitrogen compound metabolic process GO:1901564 318 0.072
single organism behavior GO:0044708 391 0.071
regulation of cellular protein metabolic process GO:0032268 243 0.070
regulation of localization GO:0032879 275 0.070
regulation of protein modification process GO:0031399 112 0.070
epithelial cell differentiation GO:0030855 322 0.069
neurological system process GO:0050877 358 0.067
chromosome organization GO:0051276 360 0.066
protein dephosphorylation GO:0006470 27 0.061
protein complex biogenesis GO:0070271 201 0.061
immune response GO:0006955 246 0.061
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.060
innate immune response GO:0045087 144 0.058
imaginal disc derived appendage development GO:0048737 399 0.058
organic substance catabolic process GO:1901575 308 0.057
cellular catabolic process GO:0044248 372 0.056
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.056
amino sugar catabolic process GO:0046348 3 0.055
appendage development GO:0048736 401 0.054
leg disc development GO:0035218 92 0.054
organelle localization GO:0051640 148 0.052
response to radiation GO:0009314 155 0.052
regulation of catalytic activity GO:0050790 185 0.051
epithelial cell migration GO:0010631 148 0.051
axon guidance GO:0007411 233 0.051
death GO:0016265 284 0.051
columnar cuboidal epithelial cell development GO:0002066 249 0.051
mating GO:0007618 120 0.051
appendage morphogenesis GO:0035107 397 0.049
growth GO:0040007 359 0.049
locomotory behavior GO:0007626 176 0.048
modification dependent protein catabolic process GO:0019941 78 0.048
sister chromatid segregation GO:0000819 92 0.048
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.048
cytoplasmic transport GO:0016482 130 0.048
modification dependent macromolecule catabolic process GO:0043632 79 0.048
chromatin organization GO:0006325 207 0.047
response to bacterium GO:0009617 198 0.047
regulation of mitotic cell cycle GO:0007346 190 0.047
cell motility GO:0048870 251 0.047
regulation of mitotic cell cycle phase transition GO:1901990 130 0.047
wing disc morphogenesis GO:0007472 344 0.047
imaginal disc derived wing morphogenesis GO:0007476 337 0.047
cell death GO:0008219 279 0.046
protein localization GO:0008104 284 0.046
spindle assembly GO:0051225 80 0.045
regulation of transport GO:0051049 181 0.045
response to external biotic stimulus GO:0043207 293 0.045
negative regulation of cell cycle GO:0045786 116 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.045
proteolysis GO:0006508 192 0.044
dna damage checkpoint GO:0000077 78 0.044
mitotic sister chromatid segregation GO:0000070 87 0.044
macromolecule catabolic process GO:0009057 161 0.044
steroid catabolic process GO:0006706 1 0.043
regulation of cellular catabolic process GO:0031329 157 0.043
negative regulation of cellular metabolic process GO:0031324 382 0.043
mitotic cell cycle phase transition GO:0044772 138 0.043
regulation of immune response GO:0050776 118 0.043
cellular ion homeostasis GO:0006873 39 0.042
organelle assembly GO:0070925 198 0.042
cognition GO:0050890 141 0.040
defense response to gram negative bacterium GO:0050829 94 0.040
histone modification GO:0016570 106 0.040
programmed cell death GO:0012501 257 0.040
regulation of cell cycle phase transition GO:1901987 130 0.040
proteasomal protein catabolic process GO:0010498 59 0.039
positive regulation of response to stimulus GO:0048584 323 0.039
ion homeostasis GO:0050801 55 0.039
intracellular signal transduction GO:0035556 300 0.039
regulation of organelle organization GO:0033043 196 0.039
organic substance transport GO:0071702 257 0.038
positive regulation of cell communication GO:0010647 250 0.038
spermatogenesis GO:0007283 200 0.038
cellular protein catabolic process GO:0044257 83 0.037
glucosamine containing compound catabolic process GO:1901072 3 0.037
negative regulation of protein metabolic process GO:0051248 85 0.037
ubiquitin dependent protein catabolic process GO:0006511 78 0.037
regulation of cell cycle process GO:0010564 181 0.037
phagocytosis GO:0006909 215 0.037
multi organism behavior GO:0051705 175 0.037
regulation of immune system process GO:0002682 176 0.036
regulation of proteasomal protein catabolic process GO:0061136 39 0.036
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.036
positive regulation of immune response GO:0050778 63 0.036
spindle organization GO:0007051 253 0.036
leg disc morphogenesis GO:0007478 80 0.036
male gamete generation GO:0048232 201 0.035
positive regulation of signaling GO:0023056 243 0.035
positive regulation of defense response GO:0031349 59 0.035
phosphorylation GO:0016310 294 0.035
protein complex assembly GO:0006461 200 0.034
regulation of response to stress GO:0080134 200 0.034
cellular amine metabolic process GO:0044106 12 0.034
cellular homeostasis GO:0019725 80 0.033
regulation of intracellular signal transduction GO:1902531 236 0.033
learning GO:0007612 75 0.033
chromosome condensation GO:0030261 41 0.032
border follicle cell migration GO:0007298 113 0.032
protein catabolic process GO:0030163 101 0.032
ethanolamine containing compound metabolic process GO:0042439 4 0.032
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.032
insemination GO:0007320 22 0.031
covalent chromatin modification GO:0016569 106 0.031
meiotic chromosome segregation GO:0045132 59 0.030
amine metabolic process GO:0009308 12 0.030
embryonic development via the syncytial blastoderm GO:0001700 148 0.030
dna integrity checkpoint GO:0031570 81 0.030
lipid metabolic process GO:0006629 121 0.030
response to abiotic stimulus GO:0009628 341 0.030
regulation of mapk cascade GO:0043408 92 0.030
regulation of catabolic process GO:0009894 170 0.030
small gtpase mediated signal transduction GO:0007264 88 0.030
homeostatic process GO:0042592 199 0.030
regionalization GO:0003002 416 0.030
protein ubiquitination GO:0016567 70 0.029
non sensory hair organization GO:0035316 47 0.029
chemosensory behavior GO:0007635 106 0.029
chromosome separation GO:0051304 42 0.029
olfactory learning GO:0008355 56 0.029
small molecule metabolic process GO:0044281 305 0.028
camera type eye development GO:0043010 4 0.028
germ line cyst formation GO:0048134 44 0.028
positive regulation of immune system process GO:0002684 68 0.028
cellular ketone metabolic process GO:0042180 24 0.028
rna processing GO:0006396 147 0.028
regulation of mitosis GO:0007088 56 0.028
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.028
macromolecular complex assembly GO:0065003 256 0.028
cell cycle phase transition GO:0044770 140 0.028
microtubule organizing center organization GO:0031023 168 0.028
exocrine system development GO:0035272 162 0.028
positive regulation of protein metabolic process GO:0051247 128 0.028
cellular chemical homeostasis GO:0055082 40 0.027
g protein coupled receptor signaling pathway GO:0007186 136 0.027
mitotic spindle organization GO:0007052 220 0.027
organonitrogen compound catabolic process GO:1901565 128 0.027
epithelium migration GO:0090132 148 0.027
regulation of molecular function GO:0065009 217 0.027
positive regulation of phosphorus metabolic process GO:0010562 139 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
centrosome organization GO:0051297 163 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.026
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.026
regulation of protein catabolic process GO:0042176 55 0.026
dna packaging GO:0006323 91 0.026
tissue migration GO:0090130 155 0.026
cell cycle checkpoint GO:0000075 95 0.026
entrainment of circadian clock by photoperiod GO:0043153 9 0.026
carbohydrate metabolic process GO:0005975 82 0.026
regulation of multicellular organismal development GO:2000026 414 0.026
negative regulation of cellular protein metabolic process GO:0032269 85 0.026
cell migration GO:0016477 238 0.026
epidermal cell differentiation GO:0009913 51 0.026
body morphogenesis GO:0010171 2 0.026
behavioral response to ethanol GO:0048149 49 0.025
microtubule bundle formation GO:0001578 27 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
organophosphate metabolic process GO:0019637 195 0.025
regulation of cellular localization GO:0060341 136 0.025
oxidation reduction process GO:0055114 123 0.025
hormone catabolic process GO:0042447 3 0.025
hair cell differentiation GO:0035315 47 0.025
chemical homeostasis GO:0048878 92 0.025
regulation of growth GO:0040008 233 0.025
cellular carbohydrate metabolic process GO:0044262 22 0.025
single organism biosynthetic process GO:0044711 206 0.024
cellular macromolecule catabolic process GO:0044265 136 0.024
developmental programmed cell death GO:0010623 138 0.024
peripheral nervous system development GO:0007422 52 0.024
mating behavior GO:0007617 106 0.024
transmembrane transport GO:0055085 139 0.024
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.024
chromatin modification GO:0016568 147 0.024
sperm competition GO:0046692 21 0.024
meiotic cell cycle GO:0051321 171 0.024
neurotransmitter metabolic process GO:0042133 2 0.024
rrna processing GO:0006364 3 0.023
regulation of cell differentiation GO:0045595 302 0.023
mapk cascade GO:0000165 107 0.023
spindle assembly involved in mitosis GO:0090307 50 0.023
single organism carbohydrate metabolic process GO:0044723 72 0.023
regulation of defense response GO:0031347 102 0.023
cellular protein localization GO:0034613 160 0.023
cell proliferation GO:0008283 299 0.023
positive regulation of signal transduction GO:0009967 223 0.023
regulation of cell death GO:0010941 173 0.023
signal transduction by phosphorylation GO:0023014 107 0.023
synaptic transmission GO:0007268 288 0.023
negative regulation of cellular component organization GO:0051129 108 0.023
regulation of anatomical structure size GO:0090066 163 0.023
learning or memory GO:0007611 141 0.023
regulation of proteolysis GO:0030162 87 0.022
regulation of erk1 and erk2 cascade GO:0070372 39 0.022
regulation of cellular protein catabolic process GO:1903362 44 0.022
regulation of cell division GO:0051302 72 0.022
regulation of nervous system development GO:0051960 248 0.022
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.022
regulation of ras protein signal transduction GO:0046578 93 0.022
cell adhesion GO:0007155 136 0.022
compound eye development GO:0048749 307 0.022
regulation of synapse structure and activity GO:0050803 128 0.022
salivary gland morphogenesis GO:0007435 145 0.022
oxoacid metabolic process GO:0043436 103 0.022
cellular macromolecule localization GO:0070727 220 0.022
erk1 and erk2 cascade GO:0070371 39 0.022
negative regulation of response to stimulus GO:0048585 258 0.022
mitotic sister chromatid separation GO:0051306 30 0.022
respiratory system development GO:0060541 213 0.022
eye development GO:0001654 323 0.021
regulation of sister chromatid segregation GO:0033045 28 0.021
endomembrane system organization GO:0010256 119 0.021
olfactory behavior GO:0042048 97 0.021
regulation of phosphorylation GO:0042325 147 0.021
regulation of small gtpase mediated signal transduction GO:0051056 93 0.021
aging GO:0007568 143 0.021
gland morphogenesis GO:0022612 145 0.021
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.021
regulation of circadian rhythm GO:0042752 49 0.021
negative regulation of signal transduction GO:0009968 206 0.021
eye morphogenesis GO:0048592 260 0.020
alcohol metabolic process GO:0006066 25 0.020
salivary gland development GO:0007431 162 0.020
negative regulation of gene expression GO:0010629 387 0.020
regulation of chromosome organization GO:0033044 64 0.020
metaphase anaphase transition of cell cycle GO:0044784 28 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
intracellular transport GO:0046907 228 0.020
meiotic nuclear division GO:0007126 151 0.020
regulation of cytoskeleton organization GO:0051493 89 0.020
positive regulation of phosphate metabolic process GO:0045937 139 0.019
response to organic substance GO:0010033 284 0.019
protein modification by small protein conjugation GO:0032446 79 0.019
negative regulation of cell cycle phase transition GO:1901988 103 0.019
chromosome localization GO:0050000 20 0.019
localization of cell GO:0051674 257 0.019
female germ line cyst formation GO:0048135 42 0.019
dendrite development GO:0016358 204 0.019
chitin catabolic process GO:0006032 3 0.019
ovarian follicle cell migration GO:0007297 121 0.019
cell growth GO:0016049 108 0.019
entrainment of circadian clock GO:0009649 16 0.019
organic hydroxy compound metabolic process GO:1901615 83 0.019
segmentation GO:0035282 207 0.019
germarium derived female germ line cyst formation GO:0030727 42 0.019
detection of stimulus GO:0051606 156 0.019
epidermis development GO:0008544 65 0.019
dna metabolic process GO:0006259 227 0.019
developmental growth GO:0048589 280 0.019
associative learning GO:0008306 65 0.018
negative regulation of phosphate metabolic process GO:0045936 45 0.018
microtubule based movement GO:0007018 51 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
cation transport GO:0006812 110 0.018
regulation of neurogenesis GO:0050767 158 0.018
single organism intracellular transport GO:1902582 207 0.018
cell cycle arrest GO:0007050 4 0.018
negative regulation of organelle organization GO:0010639 56 0.018
connective tissue development GO:0061448 3 0.018
positive regulation of intracellular signal transduction GO:1902533 116 0.018
central nervous system development GO:0007417 201 0.018
apoptotic process GO:0006915 159 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
chromatin silencing GO:0006342 76 0.018
regulation of epithelial cell proliferation GO:0050678 4 0.018
dna dependent dna replication GO:0006261 17 0.017
negative regulation of catalytic activity GO:0043086 42 0.017
positive regulation of multicellular organismal process GO:0051240 143 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
tissue death GO:0016271 102 0.017
cellular polysaccharide metabolic process GO:0044264 11 0.017
asymmetric stem cell division GO:0098722 49 0.017
regulation of mitotic sister chromatid separation GO:0010965 28 0.017
regulation of nuclear division GO:0051783 58 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
histolysis GO:0007559 102 0.017
compound eye morphogenesis GO:0001745 249 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
regulation of erbb signaling pathway GO:1901184 42 0.017
regulation of developmental growth GO:0048638 174 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
nuclear transport GO:0051169 72 0.017
response to organophosphorus GO:0046683 2 0.016
spindle checkpoint GO:0031577 11 0.016
developmental maturation GO:0021700 172 0.016
response to oxygen containing compound GO:1901700 200 0.016
cell projection assembly GO:0030031 94 0.016
salivary gland histolysis GO:0035070 88 0.016
negative regulation of mitotic cell cycle GO:0045930 109 0.016
multicellular organismal aging GO:0010259 140 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
ras protein signal transduction GO:0007265 88 0.016
hindbrain development GO:0030902 2 0.016
mitotic spindle checkpoint GO:0071174 11 0.016
sensory organ morphogenesis GO:0090596 260 0.016
open tracheal system development GO:0007424 204 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
ribonucleotide metabolic process GO:0009259 145 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
chaeta development GO:0022416 97 0.016
regulation of mitotic sister chromatid segregation GO:0033047 28 0.016
organic acid metabolic process GO:0006082 103 0.016
cellular lipid metabolic process GO:0044255 83 0.016
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
organic cyclic compound catabolic process GO:1901361 168 0.015
positive regulation of mapk cascade GO:0043410 63 0.015
copulation GO:0007620 26 0.015
response to heat GO:0009408 63 0.015
regulation of chromosome segregation GO:0051983 32 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
negative regulation of cell cycle process GO:0010948 109 0.015
acetylcholine metabolic process GO:0008291 2 0.015
autophagic cell death GO:0048102 83 0.015
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.015
cellular response to ethanol GO:0071361 4 0.015
negative regulation of epithelial cell proliferation GO:0050680 4 0.015
visual learning GO:0008542 4 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
establishment or maintenance of cell polarity GO:0007163 167 0.015
regulation of microtubule based process GO:0032886 49 0.015
nitrogen compound transport GO:0071705 85 0.015
chorion containing eggshell formation GO:0007304 105 0.015
cellular biogenic amine catabolic process GO:0042402 1 0.014
positive regulation of phosphorylation GO:0042327 87 0.014
lipid localization GO:0010876 54 0.014
response to temperature stimulus GO:0009266 106 0.014
synapse organization GO:0050808 196 0.014
female meiotic division GO:0007143 70 0.014
synapse assembly GO:0007416 143 0.014
cation homeostasis GO:0055080 51 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
positive regulation of transport GO:0051050 92 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
eggshell formation GO:0030703 105 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
maintenance of location GO:0051235 73 0.014
spinal cord development GO:0021510 1 0.014
determination of adult lifespan GO:0008340 137 0.014
establishment of protein localization GO:0045184 163 0.014
negative regulation of phosphorus metabolic process GO:0010563 45 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
neuron recognition GO:0008038 101 0.014
biological adhesion GO:0022610 138 0.014
blastoderm segmentation GO:0007350 159 0.014
regulation of cell development GO:0060284 215 0.014
organophosphate catabolic process GO:0046434 112 0.014
sensory perception of mechanical stimulus GO:0050954 72 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
septate junction assembly GO:0019991 26 0.014
mitotic cell cycle checkpoint GO:0007093 88 0.014
protein processing GO:0016485 68 0.014
negative regulation of cellular catabolic process GO:0031330 34 0.014
establishment of chromosome localization GO:0051303 20 0.014
skin development GO:0043588 65 0.014
response to ethanol GO:0045471 59 0.014
protein transport GO:0015031 155 0.014
photoreceptor cell differentiation GO:0046530 170 0.013
polysaccharide metabolic process GO:0005976 11 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
meiotic cell cycle process GO:1903046 132 0.013
camera type eye morphogenesis GO:0048593 2 0.013
sensory perception GO:0007600 196 0.013
organic hydroxy compound catabolic process GO:1901616 4 0.013
multicellular organismal reproductive behavior GO:0033057 110 0.013
negative regulation of homeostatic process GO:0032845 2 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
sensory perception of sound GO:0007605 56 0.013
retina development in camera type eye GO:0060041 4 0.013
monocarboxylic acid transport GO:0015718 3 0.013
jak stat cascade GO:0007259 49 0.013
energy derivation by oxidation of organic compounds GO:0015980 32 0.013
positive regulation of innate immune response GO:0045089 38 0.013
negative regulation of developmental process GO:0051093 201 0.013
negative regulation of chromosome segregation GO:0051985 14 0.013
oocyte dorsal ventral axis specification GO:0007310 34 0.013
protein maturation GO:0051604 71 0.013
spindle elongation GO:0051231 83 0.013
forebrain development GO:0030900 2 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
negative regulation of cell communication GO:0010648 223 0.013
lipid storage GO:0019915 38 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
ameboidal type cell migration GO:0001667 151 0.012
imaginal disc derived wing vein specification GO:0007474 48 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
generation of precursor metabolites and energy GO:0006091 42 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
regulation of programmed cell death GO:0043067 152 0.012
telencephalon development GO:0021537 2 0.012
long term memory GO:0007616 62 0.012
mrna processing GO:0006397 104 0.012
ion transport GO:0006811 145 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
negative regulation of protein modification process GO:0031400 29 0.012
secretion by cell GO:0032940 101 0.012
positive regulation of developmental process GO:0051094 143 0.012
glycerolipid metabolic process GO:0046486 34 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
somatic stem cell division GO:0048103 37 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
stem cell division GO:0017145 69 0.012
secretion GO:0046903 109 0.012
negative regulation of signaling GO:0023057 219 0.012
lipid biosynthetic process GO:0008610 46 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
regulation of synapse organization GO:0050807 110 0.012
small molecule catabolic process GO:0044282 21 0.012
glutathione metabolic process GO:0006749 37 0.012
purine containing compound metabolic process GO:0072521 155 0.012
kidney development GO:0001822 3 0.012
reproductive behavior GO:0019098 122 0.012
regulation of neuron differentiation GO:0045664 103 0.012
cytokinesis GO:0000910 90 0.012
germarium derived egg chamber formation GO:0007293 101 0.012
male mating behavior GO:0060179 70 0.012
regulation of cell proliferation GO:0042127 163 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
cilium organization GO:0044782 41 0.011
cilium assembly GO:0042384 38 0.011
negative regulation of neurogenesis GO:0050768 53 0.011
embryonic pattern specification GO:0009880 174 0.011
ventral furrow formation GO:0007370 17 0.011
rna localization GO:0006403 115 0.011
regulation of innate immune response GO:0045088 71 0.011
regulation of sequestering of calcium ion GO:0051282 3 0.011
negative regulation of nervous system development GO:0051961 92 0.011
neuronal stem cell division GO:0036445 35 0.011
cilium morphogenesis GO:0060271 39 0.011
axis specification GO:0009798 167 0.011
metal ion homeostasis GO:0055065 44 0.011
mitotic cytokinesis GO:0000281 50 0.011
nucleotide metabolic process GO:0009117 161 0.011
mrna splicing via spliceosome GO:0000398 73 0.011
regulation of intracellular transport GO:0032386 64 0.011
choline metabolic process GO:0019695 1 0.011
cell recognition GO:0008037 102 0.011
morphogenesis of follicular epithelium GO:0016333 36 0.011
nucleoside metabolic process GO:0009116 127 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
spermatid development GO:0007286 98 0.011

I-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.066
disease of cellular proliferation DOID:14566 0 0.025
nervous system disease DOID:863 0 0.024
cancer DOID:162 0 0.019
organ system cancer DOID:0050686 0 0.016
cardiovascular system disease DOID:1287 0 0.012
sensory system disease DOID:0050155 0 0.011