Drosophila melanogaster

96 known processes

Pk61C (Dmel_CG1210)

Protein kinase 61C

(Aliases: PDK1/Pk61C,Pdk1,1210,Pk61C/PDK1,dPDK1,PDK-1,DSTPK61,PDK1,Dmel\CG1210,dPDK-1,PDK,Dstpk61,dSTPK61,CG1201,CG1210)

Pk61C biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synapse assembly GO:0007416 143 0.993
regulation of nervous system development GO:0051960 248 0.983
synaptic growth at neuromuscular junction GO:0051124 119 0.979
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.965
regulation of growth GO:0040008 233 0.951
regulation of neurogenesis GO:0050767 158 0.940
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.933
growth GO:0040007 359 0.929
regulation of developmental growth GO:0048638 174 0.916
developmental growth GO:0048589 280 0.883
multicellular organism growth GO:0035264 46 0.877
cellular response to peptide hormone stimulus GO:0071375 28 0.817
Human
regulation of multicellular organismal development GO:2000026 414 0.813
negative regulation of cell communication GO:0010648 223 0.807
Human Mouse
regulation of phosphate metabolic process GO:0019220 210 0.803
Human
intracellular signal transduction GO:0035556 300 0.800
Human Yeast
chemotaxis GO:0006935 249 0.792
Worm
establishment of organelle localization GO:0051656 122 0.786
actin filament based process GO:0030029 220 0.785
cell proliferation GO:0008283 299 0.777
regulation of glial cell proliferation GO:0060251 11 0.768
regulation of multicellular organism growth GO:0040014 40 0.766
imaginal disc derived appendage development GO:0048737 399 0.743
regulation of response to stress GO:0080134 200 0.733
Mouse
negative regulation of signal transduction GO:0009968 206 0.731
Human Mouse
positive regulation of developmental process GO:0051094 143 0.728
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.714
regulation of cell proliferation GO:0042127 163 0.714
wing disc morphogenesis GO:0007472 344 0.700
regulation of phosphorylation GO:0042325 147 0.672
Human
establishment of localization in cell GO:0051649 402 0.671
Human Yeast Mouse
small molecule metabolic process GO:0044281 305 0.669
negative regulation of signaling GO:0023057 219 0.647
Human Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.632
peptidyl threonine phosphorylation GO:0018107 2 0.628
Human
regulation of neuroblast proliferation GO:1902692 34 0.625
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.624
positive regulation of cell migration GO:0030335 2 0.621
regulation of phosphorus metabolic process GO:0051174 210 0.616
Human
post embryonic appendage morphogenesis GO:0035120 385 0.608
organelle localization GO:0051640 148 0.604
Mouse
response to insulin GO:0032868 29 0.594
Human
cell proliferation involved in imaginal disc derived wing morphogenesis GO:0090255 2 0.588
negative regulation of developmental growth GO:0048640 64 0.570
synapse organization GO:0050808 196 0.567
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.566
Human
nucleoside triphosphate catabolic process GO:0009143 108 0.556
stem cell differentiation GO:0048863 117 0.556
aging GO:0007568 143 0.552
embryonic development via the syncytial blastoderm GO:0001700 148 0.551
negative regulation of synapse assembly GO:0051964 39 0.534
ribonucleoside metabolic process GO:0009119 127 0.518
cell cycle phase transition GO:0044770 140 0.514
embryonic morphogenesis GO:0048598 206 0.513
cellular response to dna damage stimulus GO:0006974 223 0.491
nucleobase containing compound catabolic process GO:0034655 165 0.489
Yeast
positive regulation of cell motility GO:2000147 3 0.478
organic substance transport GO:0071702 257 0.476
male gamete generation GO:0048232 201 0.472
positive regulation of catalytic activity GO:0043085 118 0.448
Human
negative regulation of response to stimulus GO:0048585 258 0.444
Human Mouse
neuroblast proliferation GO:0007405 74 0.444
positive regulation of dendrite morphogenesis GO:0050775 9 0.443
negative regulation of nervous system development GO:0051961 92 0.442
cellular lipid metabolic process GO:0044255 83 0.433
neuron projection guidance GO:0097485 241 0.417
purine nucleoside triphosphate metabolic process GO:0009144 119 0.415
transcription from rna polymerase ii promoter GO:0006366 368 0.413
guanosine containing compound metabolic process GO:1901068 74 0.412
cellular catabolic process GO:0044248 372 0.407
Yeast
regulation of dendrite morphogenesis GO:0048814 28 0.402
positive regulation of phosphate metabolic process GO:0045937 139 0.396
Human
regulation of catalytic activity GO:0050790 185 0.394
Human
regulation of intracellular signal transduction GO:1902531 236 0.392
Human
regulation of neuron differentiation GO:0045664 103 0.387
response to oxygen containing compound GO:1901700 200 0.386
Human
organophosphate metabolic process GO:0019637 195 0.386
positive regulation of hydrolase activity GO:0051345 78 0.384
Human
guanosine containing compound catabolic process GO:1901069 74 0.368
tube development GO:0035295 244 0.364
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.358
purine containing compound metabolic process GO:0072521 155 0.348
mitotic cell cycle phase transition GO:0044772 138 0.346
purine nucleoside catabolic process GO:0006152 112 0.343
phosphorylation GO:0016310 294 0.339
ras protein signal transduction GO:0007265 88 0.337
positive regulation of multicellular organism growth GO:0040018 21 0.337
regionalization GO:0003002 416 0.333
purine nucleotide catabolic process GO:0006195 109 0.332
bmp signaling pathway involved in malpighian tubule cell chemotaxis GO:0061353 3 0.332
peptidyl amino acid modification GO:0018193 105 0.324
Human
positive regulation of molecular function GO:0044093 136 0.323
Human
axon guidance GO:0007411 233 0.323
regulation of synapse organization GO:0050807 110 0.321
enzyme linked receptor protein signaling pathway GO:0007167 179 0.320
Human
regulation of hydrolase activity GO:0051336 97 0.320
Human
digestive system development GO:0055123 149 0.315
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.314
purine containing compound catabolic process GO:0072523 112 0.312
positive regulation of cellular amine metabolic process GO:0033240 0 0.311
positive regulation of cell proliferation GO:0008284 47 0.308
positive regulation of protein metabolic process GO:0051247 128 0.308
Human
positive regulation of phosphorus metabolic process GO:0010562 139 0.307
Human
regulation of cell size GO:0008361 63 0.305
gtp catabolic process GO:0006184 72 0.305
nucleoside catabolic process GO:0009164 112 0.301
cell death GO:0008219 279 0.296
cell cycle g1 s phase transition GO:0044843 31 0.296
negative regulation of neuroblast proliferation GO:0007406 27 0.294
gtp metabolic process GO:0046039 72 0.291
response to ethanol GO:0045471 59 0.289
cellular protein modification process GO:0006464 438 0.279
spermatogenesis GO:0007283 200 0.277
positive regulation of nucleoside metabolic process GO:0045979 47 0.276
positive regulation of lipid catabolic process GO:0050996 1 0.275
positive regulation of cell size GO:0045793 21 0.274
tor signaling GO:0031929 32 0.274
negative regulation of growth GO:0045926 84 0.272
regulation of cell differentiation GO:0045595 302 0.270
positive regulation of cellular component organization GO:0051130 156 0.266
Human
mapk cascade GO:0000165 107 0.265
Yeast
g1 s transition of mitotic cell cycle GO:0000082 31 0.263
regulation of gtpase activity GO:0043087 44 0.263
regulation of cell migration GO:0030334 22 0.262
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.259
carbohydrate derivative catabolic process GO:1901136 118 0.258
regulation of apoptotic process GO:0042981 130 0.257
purine ribonucleotide catabolic process GO:0009154 109 0.257
morphogenesis of an epithelium GO:0002009 276 0.257
positive regulation of cell differentiation GO:0045597 64 0.255
regulation of cellular component movement GO:0051270 42 0.252
Mouse
positive regulation of nervous system development GO:0051962 69 0.252
heterocycle catabolic process GO:0046700 166 0.252
Yeast
neuromuscular junction development GO:0007528 149 0.245
synaptic transmission GO:0007268 288 0.244
regulation of purine nucleotide catabolic process GO:0033121 48 0.241
positive regulation of cell growth GO:0030307 19 0.241
protein phosphorylation GO:0006468 169 0.238
cell motility GO:0048870 251 0.236
Human Mouse
apoptotic process GO:0006915 159 0.236
small gtpase mediated signal transduction GO:0007264 88 0.236
regulation of cell cycle phase transition GO:1901987 130 0.235
negative regulation of neurogenesis GO:0050768 53 0.234
inositol lipid mediated signaling GO:0048017 4 0.232
immune system process GO:0002376 347 0.231
Mouse
adherens junction organization GO:0034332 27 0.229
Rat
catabolic process GO:0009056 409 0.229
Yeast
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.226
ribonucleotide metabolic process GO:0009259 145 0.224
regulation of cell proliferation involved in imaginal disc derived wing morphogenesis GO:0090256 2 0.223
neural precursor cell proliferation GO:0061351 75 0.222
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.220
rho protein signal transduction GO:0007266 14 0.215
death GO:0016265 284 0.211
cellular nitrogen compound catabolic process GO:0044270 165 0.210
Yeast
positive regulation of growth GO:0045927 75 0.209
positive regulation of response to stimulus GO:0048584 323 0.209
Mouse
ribose phosphate metabolic process GO:0019693 145 0.209
insulin receptor signaling pathway GO:0008286 25 0.208
regulation of synaptic transmission GO:0050804 69 0.204
regulation of cellular response to insulin stimulus GO:1900076 17 0.204
cellular response to insulin stimulus GO:0032869 28 0.204
Human
purine ribonucleoside catabolic process GO:0046130 112 0.203
cell division GO:0051301 248 0.202
macromolecule catabolic process GO:0009057 161 0.197
Yeast
gliogenesis GO:0042063 80 0.196
phosphatidylinositol mediated signaling GO:0048015 4 0.196
negative regulation of developmental process GO:0051093 201 0.195
ribonucleoside triphosphate metabolic process GO:0009199 119 0.195
single organismal cell cell adhesion GO:0016337 45 0.193
nucleobase containing small molecule metabolic process GO:0055086 174 0.193
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.193
regulation of programmed cell death GO:0043067 152 0.192
g protein coupled receptor signaling pathway GO:0007186 136 0.189
regulation of mitotic cell cycle GO:0007346 190 0.189
positive regulation of developmental growth GO:0048639 62 0.184
regulation of peptide secretion GO:0002791 6 0.181
vesicle localization GO:0051648 55 0.180
negative regulation of autophagy GO:0010507 16 0.179
nucleoside triphosphate metabolic process GO:0009141 120 0.178
regulation of synapse assembly GO:0051963 94 0.177
purine nucleoside metabolic process GO:0042278 127 0.173
ribonucleoside triphosphate catabolic process GO:0009203 108 0.172
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.170
regulation of small gtpase mediated signal transduction GO:0051056 93 0.168
cell adhesion GO:0007155 136 0.168
Rat
reproductive behavior GO:0019098 122 0.166
regulation of ras protein signal transduction GO:0046578 93 0.165
membrane biogenesis GO:0044091 8 0.164
regulation of cellular catabolic process GO:0031329 157 0.164
Yeast
regulation of dendrite development GO:0050773 37 0.162
cellular ketone metabolic process GO:0042180 24 0.160
response to monosaccharide GO:0034284 4 0.157
glycosyl compound catabolic process GO:1901658 112 0.155
endocytosis GO:0006897 310 0.153
Yeast
response to oxidative stress GO:0006979 86 0.152
nucleotide catabolic process GO:0009166 109 0.152
regulation of neural precursor cell proliferation GO:2000177 35 0.152
positive regulation of neurogenesis GO:0050769 41 0.151
biological adhesion GO:0022610 138 0.151
Rat
purine ribonucleoside metabolic process GO:0046128 127 0.151
regulation of nucleotide catabolic process GO:0030811 48 0.150
positive regulation of protein localization to plasma membrane GO:1903078 3 0.150
Human
tissue morphogenesis GO:0048729 297 0.150
larval feeding behavior GO:0030536 15 0.149
response to other organism GO:0051707 293 0.148
regulation of protein kinase activity GO:0045859 51 0.147
Human
regulation of cellular ketone metabolic process GO:0010565 3 0.147
reactive oxygen species metabolic process GO:0072593 22 0.145
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.144
cell rearrangement involved in malpighian tubule morphogenesis GO:0061334 3 0.144
protein modification process GO:0036211 438 0.142
multicellular organismal aging GO:0010259 140 0.140
negative regulation of cell proliferation GO:0008285 69 0.140
positive regulation of biosynthetic process GO:0009891 316 0.140
embryo development ending in birth or egg hatching GO:0009792 152 0.137
defense response GO:0006952 300 0.136
positive regulation of transcription dna templated GO:0045893 266 0.136
cellular response to radiation GO:0071478 52 0.136
positive regulation of cell communication GO:0010647 250 0.134
regulation of cell development GO:0060284 215 0.133
skeletal muscle adaptation GO:0043501 1 0.132
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.131
meiotic cell cycle GO:0051321 171 0.130
response to external biotic stimulus GO:0043207 293 0.129
peptidyl tyrosine modification GO:0018212 24 0.128
signal transduction by phosphorylation GO:0023014 107 0.128
Yeast
cellular response to organonitrogen compound GO:0071417 36 0.126
Human
intracellular transport GO:0046907 228 0.123
Human Yeast Mouse
stress activated mapk cascade GO:0051403 52 0.120
regulation of cell cycle GO:0051726 291 0.120
feeding behavior GO:0007631 50 0.119
cellular response to peptide GO:1901653 28 0.118
Human
positive regulation of synapse assembly GO:0051965 29 0.115
purine nucleoside triphosphate catabolic process GO:0009146 108 0.115
asymmetric stem cell division GO:0098722 49 0.114
positive regulation of cellular catabolic process GO:0031331 95 0.113
regulation of epithelial cell differentiation GO:0030856 4 0.113
formation of anatomical boundary GO:0048859 37 0.113
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.112
peptidyl tyrosine phosphorylation GO:0018108 24 0.112
regulation of stress activated mapk cascade GO:0032872 41 0.112
positive regulation of phosphorylation GO:0042327 87 0.109
Human
negative regulation of cell cycle GO:0045786 116 0.108
ribonucleotide catabolic process GO:0009261 109 0.108
aromatic compound catabolic process GO:0019439 166 0.107
Yeast
negative regulation of intracellular signal transduction GO:1902532 57 0.106
lipid metabolic process GO:0006629 121 0.106
negative regulation of neural precursor cell proliferation GO:2000178 27 0.106
single organism behavior GO:0044708 391 0.105
Worm
cellular protein localization GO:0034613 160 0.105
Human
chitin based cuticle development GO:0040003 49 0.105
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 8 0.105
positive regulation of rna biosynthetic process GO:1902680 266 0.105
negative regulation of cell development GO:0010721 62 0.104
stem cell division GO:0017145 69 0.104
telencephalon development GO:0021537 2 0.104
regulation of mapk cascade GO:0043408 92 0.104
regulation of meiosis GO:0040020 3 0.102
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.102
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.102
regulation of neuron projection development GO:0010975 69 0.102
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.101
Human
purine ribonucleotide metabolic process GO:0009150 145 0.101
regulation of cellular amino acid metabolic process GO:0006521 0 0.100
regulation of erbb signaling pathway GO:1901184 42 0.099
dna biosynthetic process GO:0071897 24 0.099
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.098
synaptic vesicle localization GO:0097479 53 0.097
positive regulation of cell adhesion GO:0045785 10 0.097
purine nucleotide metabolic process GO:0006163 146 0.097
regulation of insulin receptor signaling pathway GO:0046626 17 0.097
malpighian tubule development GO:0072002 64 0.097
positive regulation of signal transduction GO:0009967 223 0.096
organic substance catabolic process GO:1901575 308 0.096
Yeast
negative regulation of cellular metabolic process GO:0031324 382 0.095
Human
negative regulation of phosphorylation GO:0042326 35 0.095
Human
regulation of gtp catabolic process GO:0033124 44 0.095
regulation of transport GO:0051049 181 0.093
Human Mouse
positive regulation of lipid metabolic process GO:0045834 4 0.093
regulation of anatomical structure morphogenesis GO:0022603 242 0.092
cell migration GO:0016477 238 0.092
Human Mouse
response to organonitrogen compound GO:0010243 75 0.090
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.088
organophosphate catabolic process GO:0046434 112 0.087
regulation of cell projection organization GO:0031344 92 0.087
organic cyclic compound catabolic process GO:1901361 168 0.087
Yeast
positive regulation of macromolecule metabolic process GO:0010604 405 0.087
Human
regulation of cellular component size GO:0032535 98 0.086
positive regulation of nucleic acid templated transcription GO:1903508 266 0.086
somatic muscle development GO:0007525 66 0.086
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.086
lipid storage GO:0019915 38 0.086
actin cytoskeleton reorganization GO:0031532 22 0.086
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.086
Yeast
multi multicellular organism process GO:0044706 123 0.086
female meiotic division GO:0007143 70 0.085
female meiosis chromosome segregation GO:0016321 33 0.085
actin cytoskeleton organization GO:0030036 206 0.085
appendage morphogenesis GO:0035107 397 0.084
body morphogenesis GO:0010171 2 0.083
regulation of protein phosphorylation GO:0001932 64 0.082
Human
negative regulation of cellular component organization GO:0051129 108 0.082
regulation of protein metabolic process GO:0051246 256 0.081
Human
presynaptic membrane organization GO:0097090 4 0.081
glycosyl compound metabolic process GO:1901657 127 0.080
nucleotide metabolic process GO:0009117 161 0.080
appendage development GO:0048736 401 0.080
regulation of stem cell proliferation GO:0072091 40 0.080
regulation of cellular response to stress GO:0080135 89 0.079
immune response regulating signaling pathway GO:0002764 2 0.079
Mouse
regulation of cellular amine metabolic process GO:0033238 3 0.079
positive regulation of gtpase activity GO:0043547 43 0.078
taxis GO:0042330 304 0.078
Worm
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.077
cellular macromolecule catabolic process GO:0044265 136 0.077
Yeast
protein complex disassembly GO:0043241 36 0.076
negative regulation of phosphorus metabolic process GO:0010563 45 0.075
Human
positive regulation of kinase activity GO:0033674 25 0.075
Human
developmental programmed cell death GO:0010623 138 0.074
negative regulation of multicellular organismal process GO:0051241 142 0.073
lipid localization GO:0010876 54 0.073
regulation of catabolic process GO:0009894 170 0.072
Yeast
negative regulation of mitotic cell cycle GO:0045930 109 0.072
positive regulation of secretion GO:0051047 22 0.072
single organism cellular localization GO:1902580 180 0.072
Human Mouse
regulation of hormone levels GO:0010817 40 0.072
response to glucose GO:0009749 2 0.072
secretion by cell GO:0032940 101 0.071
Mouse
programmed cell death GO:0012501 257 0.071
multicellular organismal reproductive behavior GO:0033057 110 0.071
regulation of protein localization to plasma membrane GO:1903076 7 0.071
Human
cuticle development GO:0042335 86 0.070
regulation of metal ion transport GO:0010959 15 0.070
Human
positive regulation of nucleotide metabolic process GO:0045981 55 0.070
vesicle mediated transport GO:0016192 381 0.069
Yeast Mouse
regulation of actin polymerization or depolymerization GO:0008064 27 0.069
regulation of molecular function GO:0065009 217 0.069
Human
negative regulation of catalytic activity GO:0043086 42 0.068
Human
response to starvation GO:0042594 97 0.068
single fertilization GO:0007338 24 0.067
heart process GO:0003015 37 0.067
positive regulation of signaling GO:0023056 243 0.066
regulation of rho protein signal transduction GO:0035023 20 0.066
single organism cell adhesion GO:0098602 47 0.065
activation of protein kinase activity GO:0032147 12 0.065
Human
convergent extension involved in gastrulation GO:0060027 2 0.065
negative regulation of photoreceptor cell differentiation GO:0046533 8 0.065
glycerolipid metabolic process GO:0046486 34 0.064
regulation of cell growth GO:0001558 43 0.064
regulation of anatomical structure size GO:0090066 163 0.064
cell growth GO:0016049 108 0.063
multi organism behavior GO:0051705 175 0.062
glial cell differentiation GO:0010001 35 0.062
actin polymerization or depolymerization GO:0008154 31 0.062
response to bacterium GO:0009617 198 0.062
regulation of cell cycle process GO:0010564 181 0.061
positive regulation of catabolic process GO:0009896 105 0.061
maintenance of location GO:0051235 73 0.061
extrinsic apoptotic signaling pathway GO:0097191 1 0.061
Human
positive regulation of gene expression GO:0010628 290 0.061
regulation of cellular protein metabolic process GO:0032268 243 0.060
Human
ameboidal type cell migration GO:0001667 151 0.059
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.059
behavioral response to ethanol GO:0048149 49 0.059
plasma membrane organization GO:0007009 26 0.059
Human
positive regulation of cdc42 gtpase activity GO:0043089 2 0.059
cellular amino acid metabolic process GO:0006520 61 0.058
cell maturation GO:0048469 144 0.058
positive regulation of cell development GO:0010720 61 0.058
cellular response to abiotic stimulus GO:0071214 58 0.058
chemical homeostasis GO:0048878 92 0.057
Human
cellular response to hormone stimulus GO:0032870 44 0.057
Human
epithelial cell development GO:0002064 274 0.055
Mouse
regulation of epithelial cell proliferation GO:0050678 4 0.055
pigmentation GO:0043473 75 0.055
single organism intracellular transport GO:1902582 207 0.055
Human Yeast Mouse
positive regulation of nucleotide catabolic process GO:0030813 46 0.055
regulation of rho gtpase activity GO:0032319 20 0.055
ribonucleoside catabolic process GO:0042454 112 0.055
micropyle formation GO:0046844 4 0.055
stem cell proliferation GO:0072089 88 0.054
regulation of cellular localization GO:0060341 136 0.054
Human Mouse
response to biotic stimulus GO:0009607 294 0.054
organ growth GO:0035265 56 0.054
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.053
Human
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.053
organonitrogen compound catabolic process GO:1901565 128 0.052
regulation of mitotic cell cycle phase transition GO:1901990 130 0.052
carbohydrate derivative metabolic process GO:1901135 217 0.052
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.051
carboxylic acid metabolic process GO:0019752 92 0.051
erbb signaling pathway GO:0038127 58 0.051
Human
regulation of synapse structure and activity GO:0050803 128 0.050
regulation of bmp signaling pathway GO:0030510 23 0.050
meiotic cell cycle process GO:1903046 132 0.050
determination of adult lifespan GO:0008340 137 0.050
ion transmembrane transport GO:0034220 122 0.050
nuclear transport GO:0051169 72 0.049
regulation of localization GO:0032879 275 0.049
Human Mouse
nucleoside metabolic process GO:0009116 127 0.049
imaginal disc derived appendage morphogenesis GO:0035114 395 0.049
photoreceptor cell development GO:0042461 96 0.048
regulation of actin filament length GO:0030832 27 0.048
secretion GO:0046903 109 0.048
Mouse
regulation of epidermal cell differentiation GO:0045604 3 0.048
response to hexose GO:0009746 3 0.047
hemopoiesis GO:0030097 46 0.047
generation of precursor metabolites and energy GO:0006091 42 0.047
cell competition in a multicellular organism GO:0035212 10 0.047
regulation of ras gtpase activity GO:0032318 38 0.046
actin filament organization GO:0007015 126 0.046
regulation of secretion by cell GO:1903530 39 0.046
Mouse
positive regulation of actin filament polymerization GO:0030838 11 0.046
cellular amine metabolic process GO:0044106 12 0.045
nucleoside phosphate catabolic process GO:1901292 110 0.045
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.045
regulation of autophagy GO:0010506 62 0.045
positive regulation of cell death GO:0010942 69 0.045
positive regulation of response to wounding GO:1903036 15 0.044
germarium derived oocyte fate determination GO:0007294 26 0.044
regulation of vesicle mediated transport GO:0060627 59 0.044
Mouse
organonitrogen compound metabolic process GO:1901564 318 0.044
energy derivation by oxidation of organic compounds GO:0015980 32 0.044
positive regulation of locomotion GO:0040017 8 0.044
epidermal growth factor receptor signaling pathway GO:0007173 58 0.044
Human
positive regulation of insulin receptor signaling pathway GO:0046628 3 0.043
response to organic substance GO:0010033 284 0.043
Human
asymmetric neuroblast division GO:0055059 33 0.043
regulation of nucleotide metabolic process GO:0006140 62 0.042
initiation of dorsal closure GO:0007392 12 0.042
regulation of cell adhesion GO:0030155 27 0.042
homeostatic process GO:0042592 199 0.042
Human
cytoplasmic transport GO:0016482 130 0.042
Human Yeast
response to alcohol GO:0097305 95 0.042
actin filament polymerization GO:0030041 27 0.041
mitotic dna integrity checkpoint GO:0044774 75 0.041
stress activated protein kinase signaling cascade GO:0031098 55 0.041
metal ion transport GO:0030001 74 0.040
Human
skin development GO:0043588 65 0.040
establishment of vesicle localization GO:0051650 51 0.040
salivary gland morphogenesis GO:0007435 145 0.039
phagocytosis GO:0006909 215 0.039
regulation of lipid kinase activity GO:0043550 2 0.039
neuron death GO:0070997 27 0.039
positive regulation of establishment of protein localization to plasma membrane GO:0090004 3 0.039
Human
spermatid development GO:0007286 98 0.039
regulation of compound eye cone cell fate specification GO:0042682 4 0.039
positive regulation of cellular protein metabolic process GO:0032270 118 0.038
Human
negative regulation of phosphate metabolic process GO:0045936 45 0.038
Human
imaginal disc derived wing morphogenesis GO:0007476 337 0.038
positive regulation of axon regeneration GO:0048680 3 0.038
regulation of nucleoside metabolic process GO:0009118 50 0.038
negative regulation of kinase activity GO:0033673 16 0.038
Human
peptidyl threonine modification GO:0018210 3 0.037
Human
mitotic g2 m transition checkpoint GO:0044818 70 0.037
imaginal disc pattern formation GO:0007447 91 0.037
germ line stem cell division GO:0042078 25 0.037
positive regulation of immune system process GO:0002684 68 0.037
Mouse
positive regulation of organelle organization GO:0010638 65 0.036
regulation of synaptic plasticity GO:0048167 14 0.036
positive regulation of immune response GO:0050778 63 0.036
Mouse
cell type specific apoptotic process GO:0097285 38 0.036
Mouse
histone modification GO:0016570 106 0.035
cellular cation homeostasis GO:0030003 38 0.035
Human
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.035
entry into diapause GO:0055115 1 0.035
regulation of protein complex assembly GO:0043254 42 0.035
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.035
Yeast
amine metabolic process GO:0009308 12 0.035
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.035
response to nitrogen compound GO:1901698 90 0.035
Human
regulation of jnk cascade GO:0046328 40 0.035
fertilization GO:0009566 26 0.035
oocyte maturation GO:0001556 3 0.035
response to transforming growth factor beta GO:0071559 18 0.034
Human
actin filament bundle organization GO:0061572 28 0.034
regulation of immune response GO:0050776 118 0.034
Mouse
embryonic hindgut morphogenesis GO:0048619 48 0.034
regulation of translation GO:0006417 56 0.034
regulation of apoptotic signaling pathway GO:2001233 10 0.033
establishment of cell polarity GO:0030010 40 0.033
trunk segmentation GO:0035290 8 0.033
endomembrane system organization GO:0010256 119 0.033
Human
response to peptide hormone GO:0043434 29 0.033
Human
intraspecies interaction between organisms GO:0051703 4 0.033
establishment or maintenance of cell polarity GO:0007163 167 0.033
nuclear division GO:0000280 332 0.032
regulation of ion transport GO:0043269 39 0.032
Human
anterior posterior pattern specification imaginal disc GO:0007448 16 0.032
single organism catabolic process GO:0044712 228 0.032

Pk61C disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.244
organ system cancer DOID:0050686 0 0.244
cancer DOID:162 0 0.244
disease of mental health DOID:150 0 0.034
non syndromic intellectual disability DOID:0050889 0 0.034
intellectual disability DOID:1059 0 0.034
developmental disorder of mental health DOID:0060037 0 0.034
specific developmental disorder DOID:0060038 0 0.034