Drosophila melanogaster

103 known processes

Orc2 (Dmel_CG3041)

Origin recognition complex subunit 2

(Aliases: fs(3)293-19,l(3)dsl5,DmOrc2p,l(3)88Ab,fs(3)293,l(3)A5,l(3)SG44,ORC2,Orc2p,k43,Orc-2,Dmel\CG3041,orc2,DmORC2,CG3041,l(3)k43,DmORC 2,ORC,rDmORC,l(3)K43)

Orc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 227 0.989
mitotic chromosome condensation GO:0007076 22 0.988
chromosome organization GO:0051276 360 0.979
nuclear dna replication GO:0033260 1 0.978
Yeast
dna conformation change GO:0071103 105 0.978
chromosome condensation GO:0030261 41 0.977
dna replication initiation GO:0006270 6 0.976
dna replication GO:0006260 48 0.967
cell cycle dna replication GO:0044786 23 0.965
Yeast
mitotic nuclear division GO:0007067 213 0.950
chromosome segregation GO:0007059 157 0.930
sister chromatid segregation GO:0000819 92 0.899
dna amplification GO:0006277 11 0.876
organelle fission GO:0048285 340 0.794
dna dependent dna replication GO:0006261 17 0.793
eggshell chorion gene amplification GO:0007307 9 0.761
dna packaging GO:0006323 91 0.760
spindle assembly involved in mitosis GO:0090307 50 0.663
regulation of cell cycle GO:0051726 291 0.644
spindle organization GO:0007051 253 0.635
dna endoreduplication GO:0042023 22 0.626
nuclear division GO:0000280 332 0.560
single organism biosynthetic process GO:0044711 206 0.523
mitotic sister chromatid separation GO:0051306 30 0.459
meiotic chromosome segregation GO:0045132 59 0.447
mitotic spindle organization GO:0007052 220 0.445
regulation of cell cycle process GO:0010564 181 0.441
mitotic sister chromatid segregation GO:0000070 87 0.427
regulation of mitotic sister chromatid separation GO:0010965 28 0.303
cellular macromolecular complex assembly GO:0034622 153 0.301
Yeast
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.292
dna geometric change GO:0032392 16 0.266
regulation of mitotic cell cycle GO:0007346 190 0.258
gene silencing GO:0016458 138 0.257
Yeast
regulation of neurogenesis GO:0050767 158 0.255
organelle assembly GO:0070925 198 0.248
protein complex assembly GO:0006461 200 0.247
cell division GO:0051301 248 0.233
mitotic centrosome separation GO:0007100 8 0.223
regulation of mitotic sister chromatid segregation GO:0033047 28 0.214
macromolecular complex assembly GO:0065003 256 0.213
Yeast
protein dna complex assembly GO:0065004 63 0.188
Yeast
regulation of mitotic spindle organization GO:0060236 9 0.187
spindle midzone assembly GO:0051255 4 0.180
mitotic spindle stabilization GO:0043148 6 0.163
body morphogenesis GO:0010171 2 0.162
Worm
meiotic cell cycle process GO:1903046 132 0.154
centrosome cycle GO:0007098 137 0.153
regulation of organelle organization GO:0033043 196 0.150
purine nucleotide catabolic process GO:0006195 109 0.149
female meiosis chromosome segregation GO:0016321 33 0.147
spindle assembly GO:0051225 80 0.138
microtubule organizing center organization GO:0031023 168 0.136
dna integrity checkpoint GO:0031570 81 0.135
regulation of gene silencing GO:0060968 63 0.133
cell cycle checkpoint GO:0000075 95 0.129
pronuclear migration GO:0035046 4 0.126
positive regulation of cell cycle GO:0045787 43 0.125
regulation of small gtpase mediated signal transduction GO:0051056 93 0.117
negative regulation of cellular biosynthetic process GO:0031327 277 0.116
Yeast
dendrite development GO:0016358 204 0.115
dna damage checkpoint GO:0000077 78 0.112
axonogenesis GO:0007409 290 0.110
negative regulation of biosynthetic process GO:0009890 277 0.110
Yeast
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.107
Yeast
imaginal disc derived appendage development GO:0048737 399 0.107
positive regulation of cellular catabolic process GO:0031331 95 0.106
single organism catabolic process GO:0044712 228 0.105
cytokinesis GO:0000910 90 0.103
negative regulation of gene expression epigenetic GO:0045814 77 0.103
Yeast
dna replication checkpoint GO:0000076 8 0.102
carbohydrate derivative metabolic process GO:1901135 217 0.101
mitotic dna damage checkpoint GO:0044773 74 0.100
metaphase anaphase transition of cell cycle GO:0044784 28 0.099
microtubule polymerization or depolymerization GO:0031109 39 0.099
post embryonic appendage morphogenesis GO:0035120 385 0.098
regulation of cell development GO:0060284 215 0.095
female meiotic division GO:0007143 70 0.094
oocyte maturation GO:0001556 3 0.093
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.092
cellular response to dna damage stimulus GO:0006974 223 0.091
cytoskeleton dependent cytokinesis GO:0061640 81 0.090
centrosome organization GO:0051297 163 0.090
larval development GO:0002164 104 0.090
Worm
nucleotide metabolic process GO:0009117 161 0.090
dendrite morphogenesis GO:0048813 199 0.090
regulation of mitosis GO:0007088 56 0.088
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.087
Yeast
ras protein signal transduction GO:0007265 88 0.087
regulation of spindle organization GO:0090224 17 0.085
meiotic spindle organization GO:0000212 36 0.084
appendage morphogenesis GO:0035107 397 0.083
nucleotide catabolic process GO:0009166 109 0.080
cellular protein modification process GO:0006464 438 0.080
Yeast
regulation of spindle elongation GO:0032887 1 0.080
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.079
negative regulation of protein complex disassembly GO:0043242 23 0.078
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.077
chromatin organization GO:0006325 207 0.071
Yeast
regulation of gene expression epigenetic GO:0040029 128 0.071
Yeast
organonitrogen compound catabolic process GO:1901565 128 0.069
g2 dna damage checkpoint GO:0031572 69 0.069
mitotic spindle elongation GO:0000022 81 0.068
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.068
purine ribonucleotide catabolic process GO:0009154 109 0.067
regulation of cell division GO:0051302 72 0.067
dna biosynthetic process GO:0071897 24 0.065
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.063
negative regulation of mitotic cell cycle GO:0045930 109 0.063
dna duplex unwinding GO:0032508 16 0.063
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.060
purine containing compound catabolic process GO:0072523 112 0.060
negative regulation of rna metabolic process GO:0051253 251 0.059
Yeast
regulation of cytoskeleton organization GO:0051493 89 0.058
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.056
mitotic cytokinesis GO:0000281 50 0.056
regulation of chromatin silencing GO:0031935 36 0.056
appendage development GO:0048736 401 0.056
nucleobase containing small molecule metabolic process GO:0055086 174 0.054
neuron projection guidance GO:0097485 241 0.054
regulation of mitotic spindle elongation GO:0032888 1 0.054
regulation of catalytic activity GO:0050790 185 0.050
organic substance catabolic process GO:1901575 308 0.050
nucleoside triphosphate catabolic process GO:0009143 108 0.050
purine nucleoside triphosphate metabolic process GO:0009144 119 0.048
protein complex biogenesis GO:0070271 201 0.048
meiosis i GO:0007127 59 0.047
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.047
purine nucleoside metabolic process GO:0042278 127 0.047
regulation of localization GO:0032879 275 0.046
gliogenesis GO:0042063 80 0.046
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.046
ribonucleoside triphosphate catabolic process GO:0009203 108 0.046
rna processing GO:0006396 147 0.045
negative regulation of cell cycle GO:0045786 116 0.045
positive regulation of cell cycle process GO:0090068 28 0.045
nucleoside catabolic process GO:0009164 112 0.045
regulation of mitotic cell cycle phase transition GO:1901990 130 0.045
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.044
catabolic process GO:0009056 409 0.044
mitotic dna integrity checkpoint GO:0044774 75 0.043
ribonucleoside catabolic process GO:0042454 112 0.043
negative regulation of gene expression GO:0010629 387 0.043
Yeast
small gtpase mediated signal transduction GO:0007264 88 0.043
cell cycle phase transition GO:0044770 140 0.043
mitotic g2 dna damage checkpoint GO:0007095 69 0.042
chromosome separation GO:0051304 42 0.042
purine ribonucleoside metabolic process GO:0046128 127 0.041
imaginal disc derived appendage morphogenesis GO:0035114 395 0.040
chemotaxis GO:0006935 249 0.040
neuron recognition GO:0008038 101 0.040
establishment of spindle orientation GO:0051294 18 0.040
axon development GO:0061564 297 0.039
positive regulation of gene expression GO:0010628 290 0.039
regulation of cellular amine metabolic process GO:0033238 3 0.039
negative regulation of nucleic acid templated transcription GO:1903507 240 0.039
Yeast
positive regulation of gliogenesis GO:0014015 5 0.038
ribose phosphate metabolic process GO:0019693 145 0.038
regulation of neuron differentiation GO:0045664 103 0.038
phagocytosis GO:0006909 215 0.037
telomere capping GO:0016233 11 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.037
eggshell chorion assembly GO:0007306 66 0.037
negative regulation of organelle organization GO:0010639 56 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.036
germarium derived oocyte fate determination GO:0007294 26 0.036
regulation of microtubule based process GO:0032886 49 0.036
single organism cellular localization GO:1902580 180 0.035
regulation of neuron projection development GO:0010975 69 0.035
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.035
ribonucleotide metabolic process GO:0009259 145 0.034
aromatic compound catabolic process GO:0019439 166 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.034
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.034
Yeast
nucleoside phosphate catabolic process GO:1901292 110 0.034
purine ribonucleotide metabolic process GO:0009150 145 0.033
heterocycle catabolic process GO:0046700 166 0.033
cardiovascular system development GO:0072358 82 0.033
negative regulation of cell cycle process GO:0010948 109 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.032
Yeast
regulation of dna replication GO:0006275 13 0.032
glycosyl compound catabolic process GO:1901658 112 0.031
endomembrane system organization GO:0010256 119 0.031
wing disc morphogenesis GO:0007472 344 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.030
dna repair GO:0006281 54 0.030
response to other organism GO:0051707 293 0.030
negative regulation of cellular metabolic process GO:0031324 382 0.029
Yeast
columnar cuboidal epithelial cell development GO:0002066 249 0.029
embryo development ending in birth or egg hatching GO:0009792 152 0.029
Worm
regulation of wnt signaling pathway GO:0030111 68 0.029
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.028
regulation of nuclear division GO:0051783 58 0.028
meiotic nuclear division GO:0007126 151 0.028
response to external biotic stimulus GO:0043207 293 0.027
positive regulation of neurogenesis GO:0050769 41 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
endocytosis GO:0006897 310 0.027
positive regulation of phosphate metabolic process GO:0045937 139 0.026
membrane organization GO:0061024 112 0.026
purine ribonucleoside catabolic process GO:0046130 112 0.026
purine nucleoside catabolic process GO:0006152 112 0.026
positive regulation of cellular component organization GO:0051130 156 0.025
positive regulation of nucleotide metabolic process GO:0045981 55 0.025
positive regulation of mitotic cell cycle GO:0045931 34 0.025
regulation of chromosome organization GO:0033044 64 0.025
cellular protein complex assembly GO:0043623 71 0.025
negative regulation of protein depolymerization GO:1901880 23 0.025
ribonucleotide catabolic process GO:0009261 109 0.024
nucleobase containing compound catabolic process GO:0034655 165 0.024
nucleoside triphosphate metabolic process GO:0009141 120 0.024
organonitrogen compound metabolic process GO:1901564 318 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.024
mitotic cell cycle checkpoint GO:0007093 88 0.023
purine nucleoside triphosphate catabolic process GO:0009146 108 0.023
cellular nitrogen compound catabolic process GO:0044270 165 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
mitotic metaphase plate congression GO:0007080 13 0.023
purine nucleotide metabolic process GO:0006163 146 0.023
dna recombination GO:0006310 32 0.022
chromosome movement towards spindle pole GO:0051305 4 0.022
double strand break repair GO:0006302 26 0.021
eye photoreceptor cell differentiation GO:0001754 145 0.021
positive regulation of dna endoreduplication GO:0032877 4 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.021
sex differentiation GO:0007548 81 0.020
Worm
regulation of molecular function GO:0065009 217 0.020
purine containing compound metabolic process GO:0072521 155 0.020
regulation of dendrite development GO:0050773 37 0.020
oxoacid metabolic process GO:0043436 103 0.020
regulation of purine nucleotide catabolic process GO:0033121 48 0.020
vesicle mediated transport GO:0016192 381 0.019
regulation of catabolic process GO:0009894 170 0.019
organophosphate catabolic process GO:0046434 112 0.019
sensory organ precursor cell division GO:0045035 10 0.019
axon guidance GO:0007411 233 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
positive regulation of developmental process GO:0051094 143 0.019
Worm
neuron remodeling GO:0016322 29 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
Worm
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
nucleocytoplasmic transport GO:0006913 72 0.019
protein transport GO:0015031 155 0.019
cellular macromolecule catabolic process GO:0044265 136 0.018
lateral inhibition GO:0046331 206 0.018
embryonic cleavage GO:0040016 5 0.018
cellular catabolic process GO:0044248 372 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
mitotic g2 m transition checkpoint GO:0044818 70 0.018
positive regulation of cell proliferation GO:0008284 47 0.017
establishment of localization in cell GO:0051649 402 0.017
mitotic dna replication checkpoint GO:0033314 5 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
photoreceptor cell differentiation GO:0046530 170 0.017
golgi organization GO:0007030 66 0.017
response to biotic stimulus GO:0009607 294 0.017
spindle assembly involved in female meiosis GO:0007056 14 0.017
chromatin remodeling GO:0006338 72 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
small molecule metabolic process GO:0044281 305 0.016
distributive segregation GO:0032837 6 0.016
female meiosis i GO:0007144 8 0.016
regulation of dna metabolic process GO:0051052 34 0.016
regulation of cell cycle phase transition GO:1901987 130 0.016
mitotic spindle midzone assembly GO:0051256 1 0.016
meiotic cell cycle GO:0051321 171 0.016
taxis GO:0042330 304 0.016
positive regulation of proteolysis GO:0045862 52 0.015
spindle assembly involved in meiosis GO:0090306 20 0.015
regulation of purine nucleotide metabolic process GO:1900542 62 0.015
positive regulation of catabolic process GO:0009896 105 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
Yeast
positive regulation of catalytic activity GO:0043085 118 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
chromatin silencing GO:0006342 76 0.015
Yeast
positive regulation of hydrolase activity GO:0051345 78 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
regulation of nucleotide metabolic process GO:0006140 62 0.015
meiotic cytokinesis GO:0033206 33 0.015
phosphorylation GO:0016310 294 0.015
organic substance transport GO:0071702 257 0.014
translesion synthesis GO:0019985 2 0.014
intracellular signal transduction GO:0035556 300 0.014
oocyte fate determination GO:0030716 27 0.014
regulation of multicellular organism growth GO:0040014 40 0.014
Worm
peptidyl amino acid modification GO:0018193 105 0.014
cell migration GO:0016477 238 0.014
regulation of ras protein signal transduction GO:0046578 93 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
postreplication repair GO:0006301 2 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.014
cellular response to growth factor stimulus GO:0071363 30 0.013
pole cell formation GO:0007279 19 0.013
immune response GO:0006955 246 0.013
regulation of heterochromatin assembly GO:0031445 8 0.013
organophosphate metabolic process GO:0019637 195 0.013
regulation of hydrolase activity GO:0051336 97 0.013
positive regulation of cell communication GO:0010647 250 0.013
regulation of chromosome segregation GO:0051983 32 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
meiotic sister chromatid segregation GO:0045144 6 0.013
open tracheal system development GO:0007424 204 0.012
organic acid metabolic process GO:0006082 103 0.012
negative regulation of cell communication GO:0010648 223 0.012
positive regulation of organelle organization GO:0010638 65 0.012
cell fate determination GO:0001709 91 0.012
eggshell formation GO:0030703 105 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
cell death GO:0008219 279 0.012
epithelial cell development GO:0002064 274 0.012
targeting of mrna for destruction involved in rna interference GO:0030423 4 0.012
microtubule bundle formation GO:0001578 27 0.012
regulation of rac protein signal transduction GO:0035020 3 0.012
anatomical structure homeostasis GO:0060249 97 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.012
protein dna complex subunit organization GO:0071824 86 0.012
Yeast
wnt signaling pathway GO:0016055 98 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
kinetochore organization GO:0051383 9 0.012
notch signaling pathway GO:0007219 120 0.011
macromolecule catabolic process GO:0009057 161 0.011
tube development GO:0035295 244 0.011
regulation of nucleotide catabolic process GO:0030811 48 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
cell proliferation GO:0008283 299 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
cytoplasmic transport GO:0016482 130 0.011
atp metabolic process GO:0046034 49 0.011
positive regulation of signal transduction GO:0009967 223 0.011
nuclear import GO:0051170 51 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
regulation of cellular protein catabolic process GO:1903362 44 0.011
cell cycle g1 s phase transition GO:0044843 31 0.011
organelle fusion GO:0048284 46 0.011
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.011
regulation of cellular localization GO:0060341 136 0.011
spermatogenesis GO:0007283 200 0.011
regulation of sister chromatid cohesion GO:0007063 2 0.011
epithelial cell differentiation GO:0030855 322 0.011
regulation of transcription by chromatin organization GO:0034401 3 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
cellular protein catabolic process GO:0044257 83 0.010
telomere organization GO:0032200 21 0.010
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.010
nitrogen compound transport GO:0071705 85 0.010
establishment of protein localization to organelle GO:0072594 62 0.010

Orc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org