Drosophila melanogaster

89 known processes

NELF-B (Dmel_CG32721)

CG32721 gene product from transcript CG32721-RA

(Aliases: CG32721,CG12152,BcDNA:GH10333,NELF,Dmel\CG32721)

NELF-B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization in cell GO:0051649 402 0.203
rna processing GO:0006396 147 0.156
regulation of cell cycle GO:0051726 291 0.146
regulation of cell cycle process GO:0010564 181 0.125
nuclear division GO:0000280 332 0.123
mitotic nuclear division GO:0007067 213 0.121
negative regulation of cell cycle process GO:0010948 109 0.120
regulation of mitotic cell cycle GO:0007346 190 0.119
single organism cellular localization GO:1902580 180 0.118
positive regulation of rna metabolic process GO:0051254 271 0.115
negative regulation of cell cycle GO:0045786 116 0.114
cell cell signaling involved in cell fate commitment GO:0045168 210 0.104
regulation of catabolic process GO:0009894 170 0.095
lateral inhibition GO:0046331 206 0.087
regionalization GO:0003002 416 0.086
negative regulation of gene expression GO:0010629 387 0.085
tube morphogenesis GO:0035239 191 0.082
regulation of mitotic cell cycle phase transition GO:1901990 130 0.081
regulation of organelle organization GO:0033043 196 0.077
organic substance transport GO:0071702 257 0.076
mitotic cell cycle phase transition GO:0044772 138 0.075
negative regulation of transcription dna templated GO:0045892 237 0.075
camera type eye development GO:0043010 4 0.075
intracellular transport GO:0046907 228 0.075
response to abiotic stimulus GO:0009628 341 0.074
regulation of molecular function GO:0065009 217 0.072
single organism intracellular transport GO:1902582 207 0.072
sister chromatid segregation GO:0000819 92 0.072
mitotic sister chromatid segregation GO:0000070 87 0.070
dorsal ventral pattern formation GO:0009953 133 0.070
negative regulation of rna metabolic process GO:0051253 251 0.069
gene silencing GO:0016458 138 0.068
regulation of cell cycle phase transition GO:1901987 130 0.067
mrna metabolic process GO:0016071 124 0.066
protein localization GO:0008104 284 0.065
organonitrogen compound metabolic process GO:1901564 318 0.064
cellular protein modification process GO:0006464 438 0.064
tube development GO:0035295 244 0.064
regulation of protein metabolic process GO:0051246 256 0.062
protein targeting GO:0006605 64 0.061
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.059
cellular amine metabolic process GO:0044106 12 0.059
organelle fission GO:0048285 340 0.058
cellular ketone metabolic process GO:0042180 24 0.058
protein modification process GO:0036211 438 0.057
negative regulation of cell cycle phase transition GO:1901988 103 0.055
cytoplasmic transport GO:0016482 130 0.055
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.054
nuclear transport GO:0051169 72 0.054
rna localization GO:0006403 115 0.053
negative regulation of mitotic cell cycle GO:0045930 109 0.052
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.052
response to other organism GO:0051707 293 0.051
regulation of developmental growth GO:0048638 174 0.051
regulation of cellular catabolic process GO:0031329 157 0.051
regulation of programmed cell death GO:0043067 152 0.050
single organism biosynthetic process GO:0044711 206 0.050
programmed cell death GO:0012501 257 0.050
regulation of apoptotic process GO:0042981 130 0.049
regulation of cellular protein metabolic process GO:0032268 243 0.049
intracellular protein transport GO:0006886 104 0.049
chromatin remodeling GO:0006338 72 0.048
positive regulation of macromolecule metabolic process GO:0010604 405 0.048
cellular macromolecule localization GO:0070727 220 0.047
positive regulation of gene expression GO:0010628 290 0.046
notch signaling pathway GO:0007219 120 0.046
camera type eye morphogenesis GO:0048593 2 0.045
embryonic morphogenesis GO:0048598 206 0.045
taxis GO:0042330 304 0.044
cell cycle phase transition GO:0044770 140 0.043
regulation of cellular ketone metabolic process GO:0010565 3 0.041
cell cycle checkpoint GO:0000075 95 0.040
regulation of gene expression epigenetic GO:0040029 128 0.040
developmental growth GO:0048589 280 0.040
protein transport GO:0015031 155 0.040
positive regulation of rna biosynthetic process GO:1902680 266 0.039
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.039
response to endogenous stimulus GO:0009719 119 0.039
positive regulation of cellular biosynthetic process GO:0031328 316 0.039
morphogenesis of an epithelium GO:0002009 276 0.038
negative regulation of cellular metabolic process GO:0031324 382 0.038
death GO:0016265 284 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
nucleocytoplasmic transport GO:0006913 72 0.036
cell proliferation GO:0008283 299 0.036
regulation of cell division GO:0051302 72 0.036
positive regulation of transcription dna templated GO:0045893 266 0.036
nuclear import GO:0051170 51 0.036
digestive system development GO:0055123 149 0.036
regulation of multicellular organismal development GO:2000026 414 0.035
negative regulation of nucleic acid templated transcription GO:1903507 240 0.035
single organism behavior GO:0044708 391 0.035
negative regulation of gene expression epigenetic GO:0045814 77 0.034
multi organism behavior GO:0051705 175 0.034
response to lipopolysaccharide GO:0032496 4 0.034
cellular protein localization GO:0034613 160 0.033
axonogenesis GO:0007409 290 0.033
oxoacid metabolic process GO:0043436 103 0.033
negative regulation of signaling GO:0023057 219 0.033
positive regulation of response to stimulus GO:0048584 323 0.033
eye morphogenesis GO:0048592 260 0.033
chromosome segregation GO:0007059 157 0.032
defense response GO:0006952 300 0.032
response to organic substance GO:0010033 284 0.032
response to radiation GO:0009314 155 0.031
protein localization to nucleus GO:0034504 55 0.031
positive regulation of mitotic cell cycle GO:0045931 34 0.031
cell division GO:0051301 248 0.031
cell death GO:0008219 279 0.031
eye development GO:0001654 323 0.031
regulation of cellular amino acid metabolic process GO:0006521 0 0.031
cellular response to abiotic stimulus GO:0071214 58 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.031
appendage morphogenesis GO:0035107 397 0.030
organic acid metabolic process GO:0006082 103 0.030
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.030
single organism nuclear import GO:1902593 51 0.030
body morphogenesis GO:0010171 2 0.030
retina development in camera type eye GO:0060041 4 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.030
negative regulation of biosynthetic process GO:0009890 277 0.029
regulation of cell differentiation GO:0045595 302 0.029
epithelial tube morphogenesis GO:0060562 88 0.029
regulation of mitosis GO:0007088 56 0.029
positive regulation of cellular amine metabolic process GO:0033240 0 0.029
regulation of chromosome organization GO:0033044 64 0.029
cellular amino acid metabolic process GO:0006520 61 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.027
regulation of cellular amine metabolic process GO:0033238 3 0.027
endomembrane system organization GO:0010256 119 0.027
response to heat GO:0009408 63 0.027
response to oxygen containing compound GO:1901700 200 0.026
post embryonic appendage morphogenesis GO:0035120 385 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.026
regulation of mitotic sister chromatid segregation GO:0033047 28 0.026
establishment of protein localization GO:0045184 163 0.026
proteolysis GO:0006508 192 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
mitotic sister chromatid separation GO:0051306 30 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
small molecule metabolic process GO:0044281 305 0.025
immune system process GO:0002376 347 0.025
regulation of mrna processing GO:0050684 71 0.025
reproductive behavior GO:0019098 122 0.025
cellular response to chemical stimulus GO:0070887 199 0.025
regulation of cell proliferation GO:0042127 163 0.024
phagocytosis GO:0006909 215 0.024
regulation of mrna splicing via spliceosome GO:0048024 64 0.024
negative regulation of cellular component organization GO:0051129 108 0.024
amine metabolic process GO:0009308 12 0.024
transcription from rna polymerase ii promoter GO:0006366 368 0.024
mrna processing GO:0006397 104 0.024
imaginal disc pattern formation GO:0007447 91 0.024
negative regulation of developmental process GO:0051093 201 0.024
negative regulation of cell death GO:0060548 81 0.024
regulation of catalytic activity GO:0050790 185 0.024
response to external biotic stimulus GO:0043207 293 0.024
protein import into nucleus GO:0006606 51 0.023
compound eye development GO:0048749 307 0.023
negative regulation of rna biosynthetic process GO:1902679 240 0.023
regulation of chromosome segregation GO:0051983 32 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
sex differentiation GO:0007548 81 0.023
regulation of gene silencing GO:0060968 63 0.023
wing disc pattern formation GO:0035222 66 0.023
reproductive system development GO:0061458 74 0.023
growth GO:0040007 359 0.023
cellular protein catabolic process GO:0044257 83 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
regulation of cell death GO:0010941 173 0.022
modification dependent macromolecule catabolic process GO:0043632 79 0.022
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.022
positive regulation of signal transduction GO:0009967 223 0.022
digestive tract morphogenesis GO:0048546 127 0.022
covalent chromatin modification GO:0016569 106 0.022
protein phosphorylation GO:0006468 169 0.022
muscle structure development GO:0061061 224 0.022
wing disc morphogenesis GO:0007472 344 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
mitotic spindle organization GO:0007052 220 0.021
apoptotic process GO:0006915 159 0.021
mitotic g2 m transition checkpoint GO:0044818 70 0.021
digestive tract development GO:0048565 149 0.021
protein catabolic process GO:0030163 101 0.021
proteasomal protein catabolic process GO:0010498 59 0.021
negative regulation of signal transduction GO:0009968 206 0.021
regulation of localization GO:0032879 275 0.021
regulation of proteasomal protein catabolic process GO:0061136 39 0.021
regulation of protein catabolic process GO:0042176 55 0.021
neural retina development GO:0003407 4 0.021
regulation of cellular protein catabolic process GO:1903362 44 0.021
protein localization to organelle GO:0033365 82 0.021
organic substance catabolic process GO:1901575 308 0.020
regulation of growth GO:0040008 233 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
appendage development GO:0048736 401 0.020
protein targeting to nucleus GO:0044744 51 0.020
aging GO:0007568 143 0.020
establishment of protein localization to organelle GO:0072594 62 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
regulation of proteolysis GO:0030162 87 0.019
phosphorylation GO:0016310 294 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.019
ubiquitin dependent protein catabolic process GO:0006511 78 0.019
negative regulation of organelle organization GO:0010639 56 0.019
mapk cascade GO:0000165 107 0.019
tissue morphogenesis GO:0048729 297 0.019
maintenance of protein location in cell GO:0032507 26 0.019
catabolic process GO:0009056 409 0.019
response to biotic stimulus GO:0009607 294 0.019
response to temperature stimulus GO:0009266 106 0.019
immune response GO:0006955 246 0.019
purine nucleoside metabolic process GO:0042278 127 0.019
chromatin modification GO:0016568 147 0.019
positive regulation of developmental process GO:0051094 143 0.018
imaginal disc derived appendage morphogenesis GO:0035114 395 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
regulation of mrna metabolic process GO:1903311 72 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
macromolecular complex assembly GO:0065003 256 0.018
protein import GO:0017038 55 0.018
cytokinesis GO:0000910 90 0.018
macromolecule catabolic process GO:0009057 161 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
neuron projection guidance GO:0097485 241 0.018
regulation of nervous system development GO:0051960 248 0.017
gland development GO:0048732 191 0.017
negative regulation of cell communication GO:0010648 223 0.017
mitotic g2 dna damage checkpoint GO:0007095 69 0.017
chromosome separation GO:0051304 42 0.017
multi multicellular organism process GO:0044706 123 0.017
regulation of cell cycle g1 s phase transition GO:1902806 23 0.017
establishment of rna localization GO:0051236 47 0.017
cell motility GO:0048870 251 0.017
single organism catabolic process GO:0044712 228 0.017
regulation of mitotic sister chromatid separation GO:0010965 28 0.017
exocrine system development GO:0035272 162 0.017
regulation of chromatin silencing GO:0031935 36 0.016
negative regulation of catabolic process GO:0009895 36 0.016
ameboidal type cell migration GO:0001667 151 0.016
cell recognition GO:0008037 102 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
golgi organization GO:0007030 66 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
regulation of meiosis GO:0040020 3 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.016
metaphase anaphase transition of cell cycle GO:0044784 28 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
spermatid differentiation GO:0048515 114 0.015
positive regulation of signaling GO:0023056 243 0.015
regulation of protein modification process GO:0031399 112 0.015
regulation of hydrolase activity GO:0051336 97 0.015
regulation of immune system process GO:0002682 176 0.015
mitotic dna damage checkpoint GO:0044773 74 0.015
positive regulation of molecular function GO:0044093 136 0.015
gastrulation GO:0007369 70 0.015
regulation of sister chromatid segregation GO:0033045 28 0.015
protein dna complex assembly GO:0065004 63 0.015
negative regulation of notch signaling pathway GO:0045746 41 0.015
intracellular signal transduction GO:0035556 300 0.015
protein maturation GO:0051604 71 0.015
regulation of protein acetylation GO:1901983 7 0.015
regulation of multi organism process GO:0043900 131 0.015
regulation of nuclear division GO:0051783 58 0.015
humoral immune response GO:0006959 117 0.014
nitrogen compound transport GO:0071705 85 0.014
embryonic pattern specification GO:0009880 174 0.014
hindbrain development GO:0030902 2 0.014
modification dependent protein catabolic process GO:0019941 78 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
chromosome organization GO:0051276 360 0.014
dna metabolic process GO:0006259 227 0.014
peptidyl amino acid modification GO:0018193 105 0.014
dna damage checkpoint GO:0000077 78 0.014
muscle organ development GO:0007517 127 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
mrna catabolic process GO:0006402 33 0.014
antimicrobial humoral response GO:0019730 99 0.014
salivary gland morphogenesis GO:0007435 145 0.014
rna 3 end processing GO:0031123 45 0.014
negative regulation of meiotic cell cycle GO:0051447 2 0.014
response to nitrogen compound GO:1901698 90 0.014
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.014
positive regulation of response to external stimulus GO:0032103 44 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.014
dna conformation change GO:0071103 105 0.014
negative regulation of apoptotic process GO:0043066 63 0.014
spindle organization GO:0007051 253 0.013
protein processing GO:0016485 68 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
regulation of small gtpase mediated signal transduction GO:0051056 93 0.013
g2 dna damage checkpoint GO:0031572 69 0.013
peptidyl lysine acetylation GO:0018394 39 0.013
leg disc development GO:0035218 92 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
regulation of multicellular organism growth GO:0040014 40 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
cytoskeleton dependent cytokinesis GO:0061640 81 0.013
rna transport GO:0050658 46 0.013
multi organism reproductive behavior GO:0044705 121 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
regulation of phosphorylation GO:0042325 147 0.013
mrna cis splicing via spliceosome GO:0045292 1 0.013
positive regulation of catabolic process GO:0009896 105 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.013
heterocycle catabolic process GO:0046700 166 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
nucleobase containing compound transport GO:0015931 56 0.013
multicellular organismal reproductive behavior GO:0033057 110 0.013
cell cycle dna replication GO:0044786 23 0.013
positive regulation of antimicrobial humoral response GO:0002760 28 0.013
rna splicing GO:0008380 83 0.012
positive regulation of mapk cascade GO:0043410 63 0.012
cell fate determination GO:0001709 91 0.012
response to reactive oxygen species GO:0000302 24 0.012
axis specification GO:0009798 167 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
telencephalon development GO:0021537 2 0.012
negative regulation of cellular catabolic process GO:0031330 34 0.012
protein dna complex subunit organization GO:0071824 86 0.012
neurological system process GO:0050877 358 0.012
defense response to other organism GO:0098542 225 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
rna splicing via transesterification reactions GO:0000375 73 0.012
positive regulation of cell migration GO:0030335 2 0.012
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.012
internal protein amino acid acetylation GO:0006475 38 0.012
kidney development GO:0001822 3 0.012
negative regulation of protein catabolic process GO:0042177 17 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
positive regulation of cell death GO:0010942 69 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
response to nutrient levels GO:0031667 114 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
salivary gland development GO:0007431 162 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
sensory organ morphogenesis GO:0090596 260 0.011
cellular catabolic process GO:0044248 372 0.011
regulation of defense response GO:0031347 102 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
central nervous system development GO:0007417 201 0.011
ras protein signal transduction GO:0007265 88 0.011
secretion GO:0046903 109 0.011
innate immune response GO:0045087 144 0.011
anterior posterior pattern specification GO:0009952 136 0.011
developmental pigmentation GO:0048066 68 0.011
protein acylation GO:0043543 42 0.011
cell cycle arrest GO:0007050 4 0.011
response to wounding GO:0009611 94 0.011
nuclear export GO:0051168 24 0.011
lipid metabolic process GO:0006629 121 0.011
dendrite development GO:0016358 204 0.011
endocytosis GO:0006897 310 0.011
spinal cord development GO:0021510 1 0.011
positive regulation of cell motility GO:2000147 3 0.011
reciprocal meiotic recombination GO:0007131 19 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
homeostatic process GO:0042592 199 0.011
negative regulation of sister chromatid segregation GO:0033046 13 0.011
connective tissue development GO:0061448 3 0.010
aromatic compound catabolic process GO:0019439 166 0.010
dna recombination GO:0006310 32 0.010
stem cell maintenance GO:0019827 67 0.010
cell adhesion GO:0007155 136 0.010
pigmentation GO:0043473 75 0.010
response to organic cyclic compound GO:0014070 89 0.010
nucleic acid transport GO:0050657 46 0.010
internal peptidyl lysine acetylation GO:0018393 38 0.010
gland morphogenesis GO:0022612 145 0.010
cell migration GO:0016477 238 0.010

NELF-B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
disease of cellular proliferation DOID:14566 0 0.014
musculoskeletal system disease DOID:17 0 0.012
cancer DOID:162 0 0.010