Drosophila melanogaster

37 known processes

Rpb4 (Dmel_CG33520)

CG33520 gene product from transcript CG33520-RF

(Aliases: Ada2a/Rpb4,Dmel\CG33520,CG7150,CG31237,ADA2a,ADA2A,CG31318,Ada2a,anon-WO0118547.402,DmRPB4,Ada2A,dAda2a,CG33520,dAda2A,dRpb4,RPB4)

Rpb4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
internal protein amino acid acetylation GO:0006475 38 0.496
chromatin organization GO:0006325 207 0.390
chromosome organization GO:0051276 360 0.379
protein acetylation GO:0006473 39 0.267
histone modification GO:0016570 106 0.225
transcription from rna polymerase ii promoter GO:0006366 368 0.209
steroid biosynthetic process GO:0006694 16 0.195
histone acetylation GO:0016573 38 0.176
protein acylation GO:0043543 42 0.161
covalent chromatin modification GO:0016569 106 0.160
chromatin remodeling GO:0006338 72 0.145
positive regulation of macromolecule metabolic process GO:0010604 405 0.144
Fly
single organism biosynthetic process GO:0044711 206 0.134
regulation of mitotic cell cycle phase transition GO:1901990 130 0.134
chromatin modification GO:0016568 147 0.129
negative regulation of cellular biosynthetic process GO:0031327 277 0.126
rna processing GO:0006396 147 0.124
morphogenesis of an epithelium GO:0002009 276 0.121
small molecule biosynthetic process GO:0044283 37 0.113
regulation of cellular protein metabolic process GO:0032268 243 0.113
Fly
small molecule metabolic process GO:0044281 305 0.112
internal peptidyl lysine acetylation GO:0018393 38 0.110
protein dna complex assembly GO:0065004 63 0.109
positive regulation of response to stimulus GO:0048584 323 0.101
regulation of protein metabolic process GO:0051246 256 0.100
Fly
cellular protein modification process GO:0006464 438 0.095
negative regulation of gene expression epigenetic GO:0045814 77 0.095
protein modification process GO:0036211 438 0.095
male gamete generation GO:0048232 201 0.095
cellular ketone metabolic process GO:0042180 24 0.087
hormone biosynthetic process GO:0042446 20 0.083
regulation of mitotic cell cycle GO:0007346 190 0.080
gene silencing GO:0016458 138 0.076
dendrite development GO:0016358 204 0.073
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.071
negative regulation of cell cycle GO:0045786 116 0.071
alcohol metabolic process GO:0006066 25 0.070
peptidyl lysine acetylation GO:0018394 39 0.069
organic hydroxy compound metabolic process GO:1901615 83 0.067
mitotic g2 dna damage checkpoint GO:0007095 69 0.066
regulation of anatomical structure morphogenesis GO:0022603 242 0.065
cellular response to dna damage stimulus GO:0006974 223 0.064
sterol biosynthetic process GO:0016126 9 0.063
protein catabolic process GO:0030163 101 0.062
organic substance catabolic process GO:1901575 308 0.061
dendrite morphogenesis GO:0048813 199 0.060
regulation of cell cycle GO:0051726 291 0.058
columnar cuboidal epithelial cell development GO:0002066 249 0.056
alcohol biosynthetic process GO:0046165 14 0.055
lipid metabolic process GO:0006629 121 0.053
regulation of rna splicing GO:0043484 69 0.052
negative regulation of biosynthetic process GO:0009890 277 0.052
spermatogenesis GO:0007283 200 0.051
histone h3 acetylation GO:0043966 11 0.049
cellular macromolecule catabolic process GO:0044265 136 0.049
localization of cell GO:0051674 257 0.048
rna splicing GO:0008380 83 0.047
ameboidal type cell migration GO:0001667 151 0.047
regulation of growth GO:0040008 233 0.047
golgi organization GO:0007030 66 0.046
peptidyl lysine modification GO:0018205 57 0.046
catabolic process GO:0009056 409 0.046
positive regulation of organelle organization GO:0010638 65 0.045
Fly
cell cycle phase transition GO:0044770 140 0.045
regulation of cell cycle phase transition GO:1901987 130 0.044
ketone biosynthetic process GO:0042181 16 0.044
regulation of gene expression epigenetic GO:0040029 128 0.044
g2 dna damage checkpoint GO:0031572 69 0.044
synaptic growth at neuromuscular junction GO:0051124 119 0.043
regulation of organelle organization GO:0033043 196 0.043
Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.042
modification dependent macromolecule catabolic process GO:0043632 79 0.042
negative regulation of rna metabolic process GO:0051253 251 0.042
cellular nitrogen compound catabolic process GO:0044270 165 0.041
positive regulation of gene expression GO:0010628 290 0.041
macromolecular complex assembly GO:0065003 256 0.040
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.040
lipid biosynthetic process GO:0008610 46 0.040
chromosome separation GO:0051304 42 0.039
positive regulation of biosynthetic process GO:0009891 316 0.039
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.039
positive regulation of protein metabolic process GO:0051247 128 0.038
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.038
chromatin assembly or disassembly GO:0006333 52 0.038
single organism catabolic process GO:0044712 228 0.037
regulation of cell cycle process GO:0010564 181 0.037
peptidyl amino acid modification GO:0018193 105 0.036
positive regulation of cellular component organization GO:0051130 156 0.036
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.035
negative regulation of cellular metabolic process GO:0031324 382 0.035
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.034
organelle assembly GO:0070925 198 0.034
cell division GO:0051301 248 0.033
positive regulation of cell communication GO:0010647 250 0.032
negative regulation of cell cycle process GO:0010948 109 0.032
chromatin assembly GO:0031497 48 0.032
positive regulation of signaling GO:0023056 243 0.032
endomembrane system organization GO:0010256 119 0.031
sterol metabolic process GO:0016125 12 0.031
regulation of multicellular organismal development GO:2000026 414 0.031
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.030
rna 3 end processing GO:0031123 45 0.030
cellular macromolecular complex assembly GO:0034622 153 0.030
cellularization GO:0007349 90 0.030
organic hydroxy compound biosynthetic process GO:1901617 21 0.029
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.029
mitotic cell cycle phase transition GO:0044772 138 0.028
negative regulation of cell cycle phase transition GO:1901988 103 0.028
compound eye development GO:0048749 307 0.028
negative regulation of gene expression GO:0010629 387 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.028
positive regulation of catalytic activity GO:0043085 118 0.028
negative regulation of nucleic acid templated transcription GO:1903507 240 0.028
regulation of cellular catabolic process GO:0031329 157 0.028
anatomical structure homeostasis GO:0060249 97 0.027
steroid metabolic process GO:0008202 20 0.027
appendage development GO:0048736 401 0.027
eye morphogenesis GO:0048592 260 0.027
positive regulation of mitotic cell cycle GO:0045931 34 0.026
mitotic sister chromatid separation GO:0051306 30 0.026
cellular hormone metabolic process GO:0034754 23 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
ecdysteroid biosynthetic process GO:0045456 15 0.025
nucleosome organization GO:0034728 59 0.025
positive regulation of cell cycle phase transition GO:1901989 20 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.024
dna packaging GO:0006323 91 0.024
regulation of mitotic sister chromatid segregation GO:0033047 28 0.024
regulation of response to stress GO:0080134 200 0.024
phagocytosis GO:0006909 215 0.024
secretion GO:0046903 109 0.024
eye development GO:0001654 323 0.024
wnt signaling pathway GO:0016055 98 0.024
protein localization GO:0008104 284 0.023
protein complex assembly GO:0006461 200 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
imaginal disc derived leg morphogenesis GO:0007480 80 0.023
compound eye morphogenesis GO:0001745 249 0.023
regulation of chromatin silencing GO:0031935 36 0.023
protein dna complex subunit organization GO:0071824 86 0.023
regulation of organ morphogenesis GO:2000027 78 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
leg disc development GO:0035218 92 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
organonitrogen compound metabolic process GO:1901564 318 0.022
positive regulation of rna metabolic process GO:0051254 271 0.022
mitotic sister chromatid segregation GO:0000070 87 0.022
single organism behavior GO:0044708 391 0.021
proteasomal protein catabolic process GO:0010498 59 0.021
regulation of catabolic process GO:0009894 170 0.021
positive regulation of cell death GO:0010942 69 0.021
regulation of mitosis GO:0007088 56 0.021
cytoplasmic transport GO:0016482 130 0.021
ovarian follicle cell development GO:0030707 248 0.020
ubiquitin dependent protein catabolic process GO:0006511 78 0.020
regulation of catalytic activity GO:0050790 185 0.020
heterocycle catabolic process GO:0046700 166 0.020
epithelial cell differentiation GO:0030855 322 0.020
programmed cell death GO:0012501 257 0.020
protein complex biogenesis GO:0070271 201 0.020
cellular catabolic process GO:0044248 372 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.020
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.019
negative regulation of transcription dna templated GO:0045892 237 0.019
positive regulation of signal transduction GO:0009967 223 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
chemical homeostasis GO:0048878 92 0.019
homeostatic process GO:0042592 199 0.019
response to gamma radiation GO:0010332 17 0.018
posttranscriptional gene silencing by rna GO:0035194 45 0.018
regulation of chromosome organization GO:0033044 64 0.018
Fly
sleep GO:0030431 49 0.018
microtubule organizing center organization GO:0031023 168 0.018
positive regulation of transcription dna templated GO:0045893 266 0.018
rna catabolic process GO:0006401 37 0.018
imaginal disc derived appendage development GO:0048737 399 0.018
mitotic g2 m transition checkpoint GO:0044818 70 0.017
rhythmic behavior GO:0007622 76 0.017
dna conformation change GO:0071103 105 0.017
regulation of sister chromatid segregation GO:0033045 28 0.017
retina development in camera type eye GO:0060041 4 0.017
dna integrity checkpoint GO:0031570 81 0.017
chaeta development GO:0022416 97 0.017
regulation of molecular function GO:0065009 217 0.017
chromatin silencing GO:0006342 76 0.017
purine nucleoside catabolic process GO:0006152 112 0.017
neuromuscular junction development GO:0007528 149 0.017
regulation of proteolysis GO:0030162 87 0.016
actin filament based process GO:0030029 220 0.016
aromatic compound catabolic process GO:0019439 166 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
nuclear division GO:0000280 332 0.016
hormone metabolic process GO:0042445 33 0.016
positive regulation of proteolysis GO:0045862 52 0.016
epithelial cell migration open tracheal system GO:0007427 32 0.016
cell death GO:0008219 279 0.015
regulation of cell division GO:0051302 72 0.015
establishment of tissue polarity GO:0007164 87 0.015
response to radiation GO:0009314 155 0.015
mrna processing GO:0006397 104 0.015
multicellular organism growth GO:0035264 46 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
endocytosis GO:0006897 310 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
cation transport GO:0006812 110 0.015
tissue morphogenesis GO:0048729 297 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
nucleotide metabolic process GO:0009117 161 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
establishment of localization in cell GO:0051649 402 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
intracellular signal transduction GO:0035556 300 0.014
modification dependent protein catabolic process GO:0019941 78 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
regulation of nuclear division GO:0051783 58 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
regulation of gene silencing GO:0060968 63 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
metaphase anaphase transition of cell cycle GO:0044784 28 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.013
regulation of protein catabolic process GO:0042176 55 0.013
regulation of synapse assembly GO:0051963 94 0.013
positive regulation of catabolic process GO:0009896 105 0.013
regulation of hydrolase activity GO:0051336 97 0.013
protein modification by small protein removal GO:0070646 28 0.013
ras protein signal transduction GO:0007265 88 0.013
regulation of cell differentiation GO:0045595 302 0.013
negative regulation of developmental process GO:0051093 201 0.012
dna damage checkpoint GO:0000077 78 0.012
histolysis GO:0007559 102 0.012
central nervous system development GO:0007417 201 0.012
sperm individualization GO:0007291 48 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
cellular lipid metabolic process GO:0044255 83 0.012
sensory organ morphogenesis GO:0090596 260 0.012
humoral immune response GO:0006959 117 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.011
proteolysis GO:0006508 192 0.011
autophagic cell death GO:0048102 83 0.011
organophosphate metabolic process GO:0019637 195 0.011
negative regulation of growth GO:0045926 84 0.011
regulation of hormone levels GO:0010817 40 0.011
positive regulation of molecular function GO:0044093 136 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
response to biotic stimulus GO:0009607 294 0.011
vesicle mediated transport GO:0016192 381 0.011
macromolecule catabolic process GO:0009057 161 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
wing disc morphogenesis GO:0007472 344 0.011
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
mitotic dna damage checkpoint GO:0044773 74 0.011
regulation of localization GO:0032879 275 0.011
organic substance transport GO:0071702 257 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010
regulation of mitotic sister chromatid separation GO:0010965 28 0.010
positive regulation of wnt signaling pathway GO:0030177 25 0.010
regulation of multi organism process GO:0043900 131 0.010
regionalization GO:0003002 416 0.010
Fly
regulation of wnt signaling pathway GO:0030111 68 0.010
regulation of chromosome segregation GO:0051983 32 0.010
gene silencing by mirna GO:0035195 22 0.010
positive regulation of gtp catabolic process GO:0033126 43 0.010
nephron development GO:0072006 3 0.010
amide biosynthetic process GO:0043604 42 0.010
sister chromatid segregation GO:0000819 92 0.010
photoreceptor cell differentiation GO:0046530 170 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
negative regulation of response to stimulus GO:0048585 258 0.010
regulation of response to external stimulus GO:0032101 115 0.010
morphogenesis of a polarized epithelium GO:0001738 93 0.010
eggshell formation GO:0030703 105 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010

Rpb4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.012