Drosophila melanogaster

36 known processes

px (Dmel_CG4444)

plexus

(Aliases: CG4444,l(2)k08134,l(2)k08316,Dmel\CG4444)

px biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of rna metabolic process GO:0051254 271 0.478
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.467
regulation of intracellular signal transduction GO:1902531 236 0.412
positive regulation of biosynthetic process GO:0009891 316 0.374
positive regulation of cellular biosynthetic process GO:0031328 316 0.299
negative regulation of transcription dna templated GO:0045892 237 0.268
positive regulation of transcription dna templated GO:0045893 266 0.264
cellular protein modification process GO:0006464 438 0.246
regulation of cellular protein metabolic process GO:0032268 243 0.220
response to oxygen containing compound GO:1901700 200 0.205
vesicle mediated transport GO:0016192 381 0.201
immune system development GO:0002520 57 0.201
ribonucleoside triphosphate catabolic process GO:0009203 108 0.200
immune system process GO:0002376 347 0.198
appendage development GO:0048736 401 0.196
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.194
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.194
positive regulation of rna biosynthetic process GO:1902680 266 0.194
negative regulation of rna biosynthetic process GO:1902679 240 0.191
transcription from rna polymerase ii promoter GO:0006366 368 0.187
regionalization GO:0003002 416 0.177
regulation of catalytic activity GO:0050790 185 0.171
purine ribonucleotide catabolic process GO:0009154 109 0.170
regulation of phosphorus metabolic process GO:0051174 210 0.152
regulation of molecular function GO:0065009 217 0.148
establishment of localization in cell GO:0051649 402 0.148
nucleobase containing compound catabolic process GO:0034655 165 0.142
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.139
regulation of immune system process GO:0002682 176 0.133
regulation of phosphate metabolic process GO:0019220 210 0.131
aromatic compound catabolic process GO:0019439 166 0.130
positive regulation of nucleic acid templated transcription GO:1903508 266 0.129
dendrite development GO:0016358 204 0.127
regulation of apoptotic process GO:0042981 130 0.125
positive regulation of hydrolase activity GO:0051345 78 0.124
negative regulation of rna metabolic process GO:0051253 251 0.121
humoral immune response GO:0006959 117 0.119
covalent chromatin modification GO:0016569 106 0.115
death GO:0016265 284 0.115
protein acetylation GO:0006473 39 0.110
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.109
positive regulation of cellular catabolic process GO:0031331 95 0.105
heterocycle catabolic process GO:0046700 166 0.103
embryo development ending in birth or egg hatching GO:0009792 152 0.102
positive regulation of multicellular organismal process GO:0051240 143 0.101
regulation of response to biotic stimulus GO:0002831 63 0.100
positive regulation of phosphorus metabolic process GO:0010562 139 0.098
purine nucleoside triphosphate metabolic process GO:0009144 119 0.094
positive regulation of catabolic process GO:0009896 105 0.094
regulation of organelle organization GO:0033043 196 0.094
programmed cell death GO:0012501 257 0.092
regulation of cellular catabolic process GO:0031329 157 0.091
positive regulation of catalytic activity GO:0043085 118 0.090
intracellular signal transduction GO:0035556 300 0.089
positive regulation of phosphate metabolic process GO:0045937 139 0.088
positive regulation of nucleotide metabolic process GO:0045981 55 0.088
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.087
negative regulation of biosynthetic process GO:0009890 277 0.086
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.086
regulation of response to external stimulus GO:0032101 115 0.085
glycosyl compound catabolic process GO:1901658 112 0.085
negative regulation of cell communication GO:0010648 223 0.085
ommochrome metabolic process GO:0046152 19 0.085
regulation of multi organism process GO:0043900 131 0.085
regulation of protein metabolic process GO:0051246 256 0.084
positive regulation of macromolecule metabolic process GO:0010604 405 0.083
rna catabolic process GO:0006401 37 0.083
organonitrogen compound metabolic process GO:1901564 318 0.083
nuclear division GO:0000280 332 0.083
regulation of localization GO:0032879 275 0.083
endocytosis GO:0006897 310 0.082
guanosine containing compound catabolic process GO:1901069 74 0.080
apoptotic process GO:0006915 159 0.078
imaginal disc derived appendage morphogenesis GO:0035114 395 0.076
regulation of response to stress GO:0080134 200 0.075
positive regulation of molecular function GO:0044093 136 0.075
catabolic process GO:0009056 409 0.075
gtp metabolic process GO:0046039 72 0.074
positive regulation of cellular component organization GO:0051130 156 0.071
purine ribonucleoside metabolic process GO:0046128 127 0.071
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.071
post embryonic appendage morphogenesis GO:0035120 385 0.070
protein complex assembly GO:0006461 200 0.070
negative regulation of nucleic acid templated transcription GO:1903507 240 0.070
cellular nitrogen compound catabolic process GO:0044270 165 0.070
nucleoside catabolic process GO:0009164 112 0.068
organic acid metabolic process GO:0006082 103 0.068
regulation of gene expression epigenetic GO:0040029 128 0.068
negative regulation of signal transduction GO:0009968 206 0.065
negative regulation of cell death GO:0060548 81 0.065
single organism behavior GO:0044708 391 0.065
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.064
macromolecular complex assembly GO:0065003 256 0.064
chromatin organization GO:0006325 207 0.063
regulation of cellular amine metabolic process GO:0033238 3 0.063
regulation of antimicrobial humoral response GO:0002759 50 0.062
cellular amino acid metabolic process GO:0006520 61 0.062
negative regulation of gene expression GO:0010629 387 0.061
purine nucleotide catabolic process GO:0006195 109 0.061
chromatin modification GO:0016568 147 0.059
cell migration GO:0016477 238 0.058
oxoacid metabolic process GO:0043436 103 0.058
regulation of hydrolase activity GO:0051336 97 0.057
cell motility GO:0048870 251 0.056
organelle fission GO:0048285 340 0.056
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.056
positive regulation of gtpase activity GO:0043547 43 0.056
purine nucleoside metabolic process GO:0042278 127 0.055
mrna metabolic process GO:0016071 124 0.055
regulation of protein modification process GO:0031399 112 0.055
regulation of gtpase activity GO:0043087 44 0.054
ribonucleotide catabolic process GO:0009261 109 0.054
organic cyclic compound catabolic process GO:1901361 168 0.052
regulation of production of molecular mediator of immune response GO:0002700 44 0.051
response to abiotic stimulus GO:0009628 341 0.051
cellular catabolic process GO:0044248 372 0.051
nucleoside triphosphate metabolic process GO:0009141 120 0.051
compound eye development GO:0048749 307 0.050
jak stat cascade GO:0007259 49 0.050
protein complex biogenesis GO:0070271 201 0.050
regulation of programmed cell death GO:0043067 152 0.050
response to external biotic stimulus GO:0043207 293 0.049
positive regulation of protein metabolic process GO:0051247 128 0.049
regulation of multicellular organismal development GO:2000026 414 0.049
regulation of endocytosis GO:0030100 37 0.049
purine ribonucleotide metabolic process GO:0009150 145 0.049
carboxylic acid metabolic process GO:0019752 92 0.048
regulation of cellular component biogenesis GO:0044087 201 0.048
negative regulation of response to stimulus GO:0048585 258 0.048
axonogenesis GO:0007409 290 0.047
organic substance catabolic process GO:1901575 308 0.047
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.047
cytoplasmic transport GO:0016482 130 0.046
purine nucleoside catabolic process GO:0006152 112 0.046
response to other organism GO:0051707 293 0.046
mrna processing GO:0006397 104 0.046
ribonucleoside triphosphate metabolic process GO:0009199 119 0.046
regulation of immune effector process GO:0002697 52 0.045
small gtpase mediated signal transduction GO:0007264 88 0.045
leg disc morphogenesis GO:0007478 80 0.045
taxis GO:0042330 304 0.045
chemotaxis GO:0006935 249 0.044
purine containing compound catabolic process GO:0072523 112 0.044
antimicrobial humoral response GO:0019730 99 0.044
nucleoside triphosphate catabolic process GO:0009143 108 0.043
imaginal disc derived appendage development GO:0048737 399 0.043
ribonucleotide metabolic process GO:0009259 145 0.042
single organism catabolic process GO:0044712 228 0.042
peptidyl amino acid modification GO:0018193 105 0.042
positive regulation of gene expression GO:0010628 290 0.042
tissue morphogenesis GO:0048729 297 0.042
cellular response to oxygen containing compound GO:1901701 79 0.042
gene silencing by mirna GO:0035195 22 0.042
body morphogenesis GO:0010171 2 0.041
negative regulation of apoptotic process GO:0043066 63 0.041
chromosome organization GO:0051276 360 0.040
ribonucleoside metabolic process GO:0009119 127 0.040
positive regulation of cellular protein metabolic process GO:0032270 118 0.040
protein modification by small protein conjugation or removal GO:0070647 106 0.040
carbohydrate derivative metabolic process GO:1901135 217 0.039
regulation of cellular amide metabolic process GO:0034248 39 0.039
multicellular organismal aging GO:0010259 140 0.039
establishment of organelle localization GO:0051656 122 0.039
regulation of cell morphogenesis GO:0022604 163 0.038
cell death GO:0008219 279 0.038
response to organic substance GO:0010033 284 0.038
negative regulation of signaling GO:0023057 219 0.038
cell division GO:0051301 248 0.037
organelle localization GO:0051640 148 0.037
positive regulation of cellular component biogenesis GO:0044089 80 0.037
nucleobase containing small molecule metabolic process GO:0055086 174 0.037
purine nucleotide metabolic process GO:0006163 146 0.037
rho protein signal transduction GO:0007266 14 0.037
segmentation GO:0035282 207 0.037
regulation of transport GO:0051049 181 0.036
glycosyl compound metabolic process GO:1901657 127 0.036
ras protein signal transduction GO:0007265 88 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.035
response to alcohol GO:0097305 95 0.035
hematopoietic or lymphoid organ development GO:0048534 57 0.034
regulation of nucleotide catabolic process GO:0030811 48 0.034
nucleoside phosphate metabolic process GO:0006753 162 0.034
nucleotide metabolic process GO:0009117 161 0.034
open tracheal system development GO:0007424 204 0.034
organophosphate metabolic process GO:0019637 195 0.034
positive regulation of nucleoside metabolic process GO:0045979 47 0.033
immune response GO:0006955 246 0.033
aging GO:0007568 143 0.033
enzyme linked receptor protein signaling pathway GO:0007167 179 0.033
purine containing compound metabolic process GO:0072521 155 0.033
regulation of dna templated transcription elongation GO:0032784 17 0.033
purine nucleoside triphosphate catabolic process GO:0009146 108 0.033
growth GO:0040007 359 0.033
small molecule metabolic process GO:0044281 305 0.032
determination of adult lifespan GO:0008340 137 0.032
nucleotide catabolic process GO:0009166 109 0.032
regulation of cellular ketone metabolic process GO:0010565 3 0.032
central nervous system development GO:0007417 201 0.032
positive regulation of protein modification process GO:0031401 58 0.032
response to biotic stimulus GO:0009607 294 0.032
regulation of small gtpase mediated signal transduction GO:0051056 93 0.032
antimicrobial peptide production GO:0002775 46 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.030
multi organism behavior GO:0051705 175 0.030
dna metabolic process GO:0006259 227 0.030
regulation of antimicrobial peptide production GO:0002784 44 0.030
cellular response to dna damage stimulus GO:0006974 223 0.030
phagocytosis GO:0006909 215 0.030
guanosine containing compound metabolic process GO:1901068 74 0.030
phosphorylation GO:0016310 294 0.030
regulation of purine nucleotide catabolic process GO:0033121 48 0.029
nucleoside metabolic process GO:0009116 127 0.029
eye development GO:0001654 323 0.029
wing disc morphogenesis GO:0007472 344 0.028
regulation of nucleoside metabolic process GO:0009118 50 0.028
cellular response to external stimulus GO:0071496 66 0.028
regulation of cellular response to stress GO:0080135 89 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
cellular response to organic substance GO:0071310 132 0.028
muscle cell differentiation GO:0042692 103 0.028
negative regulation of cellular biosynthetic process GO:0031327 277 0.027
ocellus pigmentation GO:0033060 19 0.027
hemopoiesis GO:0030097 46 0.027
positive regulation of nucleotide catabolic process GO:0030813 46 0.027
sensory organ morphogenesis GO:0090596 260 0.027
protein phosphorylation GO:0006468 169 0.027
response to organonitrogen compound GO:0010243 75 0.027
regulation of cell differentiation GO:0045595 302 0.026
peptide metabolic process GO:0006518 80 0.026
positive regulation of phosphorylation GO:0042327 87 0.026
histone modification GO:0016570 106 0.026
nephron epithelium development GO:0072009 3 0.026
regulation of cell development GO:0060284 215 0.026
gtp catabolic process GO:0006184 72 0.026
homeostatic process GO:0042592 199 0.026
single organism intracellular transport GO:1902582 207 0.026
macromolecule catabolic process GO:0009057 161 0.026
appendage morphogenesis GO:0035107 397 0.026
organophosphate catabolic process GO:0046434 112 0.025
cellular response to chemical stimulus GO:0070887 199 0.025
respiratory system development GO:0060541 213 0.025
purine ribonucleoside catabolic process GO:0046130 112 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
eye morphogenesis GO:0048592 260 0.025
ncrna metabolic process GO:0034660 43 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.024
outflow tract morphogenesis GO:0003151 4 0.024
positive regulation of gtp catabolic process GO:0033126 43 0.024
dendrite morphogenesis GO:0048813 199 0.024
regulation of cellular localization GO:0060341 136 0.024
defense response GO:0006952 300 0.024
regulation of phosphorylation GO:0042325 147 0.024
nucleoside phosphate catabolic process GO:1901292 110 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.023
regulation of gtp catabolic process GO:0033124 44 0.023
organic substance transport GO:0071702 257 0.023
locomotory behavior GO:0007626 176 0.023
striated muscle cell differentiation GO:0051146 90 0.023
regulation of cell proliferation GO:0042127 163 0.023
regulation of ras protein signal transduction GO:0046578 93 0.023
ribose phosphate metabolic process GO:0019693 145 0.023
actin cytoskeleton organization GO:0030036 206 0.023
sister chromatid segregation GO:0000819 92 0.022
response to radiation GO:0009314 155 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.022
positive regulation of response to external stimulus GO:0032103 44 0.022
protein modification by small protein removal GO:0070646 28 0.022
molting cycle chitin based cuticle GO:0007591 56 0.022
positive regulation of signaling GO:0023056 243 0.022
endomembrane system organization GO:0010256 119 0.022
tube development GO:0035295 244 0.022
spindle organization GO:0007051 253 0.021
myoblast fusion GO:0007520 43 0.021
secondary metabolic process GO:0019748 75 0.021
cellular ketone metabolic process GO:0042180 24 0.021
gland development GO:0048732 191 0.021
pigmentation GO:0043473 75 0.021
anterior posterior pattern specification GO:0009952 136 0.021
developmental pigmentation GO:0048066 68 0.021
regulation of rho protein signal transduction GO:0035023 20 0.021
regulation of immune response GO:0050776 118 0.021
larval development GO:0002164 104 0.021
regulation of nucleotide metabolic process GO:0006140 62 0.021
peptidyl lysine modification GO:0018205 57 0.020
regulation of cell cycle process GO:0010564 181 0.020
protein modification process GO:0036211 438 0.020
regulation of mitotic cell cycle GO:0007346 190 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
mrna catabolic process GO:0006402 33 0.020
ribonucleoside catabolic process GO:0042454 112 0.020
response to endogenous stimulus GO:0009719 119 0.020
regulation of humoral immune response GO:0002920 51 0.020
embryonic morphogenesis GO:0048598 206 0.020
regulation of cell cycle GO:0051726 291 0.020
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.020
response to lipid GO:0033993 38 0.020
regulation of proteolysis GO:0030162 87 0.020
regulation of cytoskeleton organization GO:0051493 89 0.019
regulation of vesicle mediated transport GO:0060627 59 0.019
golgi organization GO:0007030 66 0.019
nephron development GO:0072006 3 0.019
kidney epithelium development GO:0072073 3 0.019
myotube differentiation GO:0014902 46 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
anatomical structure homeostasis GO:0060249 97 0.018
cellular macromolecule catabolic process GO:0044265 136 0.018
embryonic pattern specification GO:0009880 174 0.018
cellular macromolecule localization GO:0070727 220 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
response to lipopolysaccharide GO:0032496 4 0.018
regulation of cell death GO:0010941 173 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.017
negative regulation of cell cycle GO:0045786 116 0.017
response to organic cyclic compound GO:0014070 89 0.017
gene silencing GO:0016458 138 0.017
negative regulation of programmed cell death GO:0043069 72 0.016
tube morphogenesis GO:0035239 191 0.016
rna processing GO:0006396 147 0.016
localization of cell GO:0051674 257 0.016
intracellular transport GO:0046907 228 0.016
cellular protein complex assembly GO:0043623 71 0.016
developmental programmed cell death GO:0010623 138 0.016
positive regulation of rho gtpase activity GO:0032321 19 0.016
regulation of transferase activity GO:0051338 58 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
stem cell development GO:0048864 79 0.016
regulation of growth GO:0040008 233 0.016
response to light stimulus GO:0009416 124 0.016
regulation of cell shape GO:0008360 113 0.015
hematopoietic progenitor cell differentiation GO:0002244 1 0.015
mitotic nuclear division GO:0007067 213 0.015
cell fate determination GO:0001709 91 0.015
peptide biosynthetic process GO:0043043 42 0.015
axon guidance GO:0007411 233 0.015
immune effector process GO:0002252 98 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
pigment metabolic process GO:0042440 84 0.015
ocellus pigment metabolic process GO:0046158 19 0.015
negative regulation of intracellular signal transduction GO:1902532 57 0.015
actin filament based process GO:0030029 220 0.015
regulation of intracellular transport GO:0032386 64 0.014
brain development GO:0007420 120 0.014
positive regulation of developmental process GO:0051094 143 0.014
leg disc development GO:0035218 92 0.014
cellular amide metabolic process GO:0043603 80 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
regulation of mrna processing GO:0050684 71 0.014
renal tubule development GO:0061326 64 0.014
negative regulation of developmental process GO:0051093 201 0.014
negative regulation of molecular function GO:0044092 51 0.014
regulation of protein localization GO:0032880 76 0.014
cell proliferation GO:0008283 299 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
protein ubiquitination GO:0016567 70 0.014
methylation GO:0032259 47 0.014
positive regulation of ras gtpase activity GO:0032320 36 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
regulation of intracellular protein transport GO:0033157 46 0.013
meiotic cell cycle GO:0051321 171 0.013
mapk cascade GO:0000165 107 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
rna 3 end processing GO:0031123 45 0.013
toll signaling pathway GO:0008063 25 0.013
developmental maturation GO:0021700 172 0.013
signal transduction in response to dna damage GO:0042770 3 0.013
oocyte development GO:0048599 124 0.013
male gamete generation GO:0048232 201 0.013
proteolysis GO:0006508 192 0.013
muscle fiber development GO:0048747 12 0.013
cellular response to endogenous stimulus GO:0071495 80 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
epithelial cell development GO:0002064 274 0.013
macromolecule methylation GO:0043414 45 0.012
regulation of ras gtpase activity GO:0032318 38 0.012
rna transport GO:0050658 46 0.012
response to nutrient levels GO:0031667 114 0.012
inter male aggressive behavior GO:0002121 60 0.012
regulation of cell division GO:0051302 72 0.012
regulation of chitin based cuticle tanning GO:0007564 14 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
regulation of purine nucleotide metabolic process GO:1900542 62 0.012
neural precursor cell proliferation GO:0061351 75 0.012
nuclear transport GO:0051169 72 0.012
actomyosin structure organization GO:0031032 56 0.012
single organism cellular localization GO:1902580 180 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
nuclear transcribed mrna catabolic process GO:0000956 24 0.012
dna templated transcription elongation GO:0006354 18 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
camera type eye development GO:0043010 4 0.011
nucleobase containing compound transport GO:0015931 56 0.011
cellular amine metabolic process GO:0044106 12 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
syncytium formation by plasma membrane fusion GO:0000768 43 0.011
aggressive behavior GO:0002118 63 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
notch signaling pathway GO:0007219 120 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
negative regulation of gene expression epigenetic GO:0045814 77 0.011
regulation of nucleocytoplasmic transport GO:0046822 35 0.011
mitotic spindle organization GO:0007052 220 0.011
positive regulation of protein phosphorylation GO:0001934 34 0.010
response to inorganic substance GO:0010035 44 0.010
regulation of protein phosphorylation GO:0001932 64 0.010
regulation of protein kinase activity GO:0045859 51 0.010
dna repair GO:0006281 54 0.010
protein localization GO:0008104 284 0.010
regulation of bmp signaling pathway GO:0030510 23 0.010
negative regulation of phosphorus metabolic process GO:0010563 45 0.010
response to monosaccharide GO:0034284 4 0.010
regulation of neural precursor cell proliferation GO:2000177 35 0.010
stem cell differentiation GO:0048863 117 0.010
urogenital system development GO:0001655 72 0.010
regulation of cytoplasmic transport GO:1903649 47 0.010
cellular response to organic cyclic compound GO:0071407 32 0.010

px disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.067
nervous system disease DOID:863 0 0.030
cardiovascular system disease DOID:1287 0 0.016
integumentary system disease DOID:16 0 0.013
hair disease DOID:421 0 0.013
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
central nervous system disease DOID:331 0 0.012
disease of metabolism DOID:0014667 0 0.011
vascular disease DOID:178 0 0.011