Drosophila melanogaster

23 known processes

UbcD2 (Dmel_CG6720)

Ubiquitin conjugating enzyme 2

(Aliases: Dmel\CG6720,ubcD2,l(2)k13206,CG6720)

UbcD2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation or removal GO:0070647 106 0.777
rna processing GO:0006396 147 0.754
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.706
cellular protein catabolic process GO:0044257 83 0.637
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.621
rna splicing via transesterification reactions GO:0000375 73 0.606
phosphorylation GO:0016310 294 0.583
protein catabolic process GO:0030163 101 0.558
rna splicing GO:0008380 83 0.553
regulation of mrna processing GO:0050684 71 0.510
proteolysis GO:0006508 192 0.510
spermatid differentiation GO:0048515 114 0.498
macromolecule catabolic process GO:0009057 161 0.486
cellular catabolic process GO:0044248 372 0.477
catabolic process GO:0009056 409 0.455
proteasomal protein catabolic process GO:0010498 59 0.405
cellular macromolecule catabolic process GO:0044265 136 0.394
protein modification by small protein conjugation GO:0032446 79 0.378
modification dependent macromolecule catabolic process GO:0043632 79 0.372
organic substance catabolic process GO:1901575 308 0.370
modification dependent protein catabolic process GO:0019941 78 0.348
mrna metabolic process GO:0016071 124 0.346
mrna splicing via spliceosome GO:0000398 73 0.337
mrna processing GO:0006397 104 0.327
cell cycle phase transition GO:0044770 140 0.326
spermatogenesis GO:0007283 200 0.318
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.310
regulation of protein metabolic process GO:0051246 256 0.303
ubiquitin dependent protein catabolic process GO:0006511 78 0.301
protein ubiquitination GO:0016567 70 0.283
regulation of phosphorus metabolic process GO:0051174 210 0.270
mitotic nuclear division GO:0007067 213 0.267
regulation of growth GO:0040008 233 0.246
organelle fission GO:0048285 340 0.226
negative regulation of developmental process GO:0051093 201 0.213
intracellular signal transduction GO:0035556 300 0.207
regulation of protein catabolic process GO:0042176 55 0.198
mitotic cell cycle phase transition GO:0044772 138 0.198
regulation of intracellular signal transduction GO:1902531 236 0.198
chromatin organization GO:0006325 207 0.198
Human
regulation of mrna splicing via spliceosome GO:0048024 64 0.177
regulation of mrna metabolic process GO:1903311 72 0.176
regulation of phosphate metabolic process GO:0019220 210 0.174
determination of adult lifespan GO:0008340 137 0.164
regulation of rna splicing GO:0043484 69 0.161
response to organic substance GO:0010033 284 0.145
regulation of cellular catabolic process GO:0031329 157 0.144
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.143
aging GO:0007568 143 0.143
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.143
protein dna complex subunit organization GO:0071824 86 0.139
cell division GO:0051301 248 0.139
protein modification process GO:0036211 438 0.137
negative regulation of gene expression GO:0010629 387 0.136
regulation of localization GO:0032879 275 0.134
regulation of proteasomal protein catabolic process GO:0061136 39 0.130
regulation of cell cycle GO:0051726 291 0.129
meiotic cell cycle GO:0051321 171 0.126
positive regulation of macromolecule metabolic process GO:0010604 405 0.125
regulation of cellular protein metabolic process GO:0032268 243 0.124
posttranscriptional regulation of gene expression GO:0010608 145 0.124
regulation of phosphorylation GO:0042325 147 0.122
chromosome organization GO:0051276 360 0.121
Human
vesicle mediated transport GO:0016192 381 0.118
chromatin assembly or disassembly GO:0006333 52 0.117
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.117
nucleosome organization GO:0034728 59 0.116
developmental maturation GO:0021700 172 0.115
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.111
nuclear division GO:0000280 332 0.104
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.102
embryo development ending in birth or egg hatching GO:0009792 152 0.097
regulation of catabolic process GO:0009894 170 0.090
positive regulation of biosynthetic process GO:0009891 316 0.084
regulation of cell cycle process GO:0010564 181 0.083
negative regulation of cellular biosynthetic process GO:0031327 277 0.083
small molecule metabolic process GO:0044281 305 0.082
positive regulation of protein metabolic process GO:0051247 128 0.082
cellular response to chemical stimulus GO:0070887 199 0.075
regulation of proteolysis GO:0030162 87 0.072
apoptotic process GO:0006915 159 0.069
negative regulation of cellular metabolic process GO:0031324 382 0.069
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.067
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.067
regulation of cell proliferation GO:0042127 163 0.066
regulation of multicellular organismal development GO:2000026 414 0.065
regulation of mitotic cell cycle phase transition GO:1901990 130 0.065
spermatid development GO:0007286 98 0.064
positive regulation of developmental process GO:0051094 143 0.064
protein k48 linked ubiquitination GO:0070936 3 0.059
Human
signal transduction by phosphorylation GO:0023014 107 0.057
protein complex assembly GO:0006461 200 0.055
regulation of cellular component biogenesis GO:0044087 201 0.055
protein modification by small protein removal GO:0070646 28 0.055
translation GO:0006412 69 0.054
male gamete generation GO:0048232 201 0.054
cell maturation GO:0048469 144 0.052
localization of cell GO:0051674 257 0.052
negative regulation of nervous system development GO:0051961 92 0.052
response to alcohol GO:0097305 95 0.049
mapk cascade GO:0000165 107 0.049
positive regulation of catabolic process GO:0009896 105 0.045
negative regulation of multicellular organismal process GO:0051241 142 0.045
endocytosis GO:0006897 310 0.043
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.043
positive regulation of transcription dna templated GO:0045893 266 0.043
positive regulation of multicellular organismal process GO:0051240 143 0.043
organonitrogen compound metabolic process GO:1901564 318 0.042
positive regulation of phosphate metabolic process GO:0045937 139 0.041
organophosphate metabolic process GO:0019637 195 0.040
protein complex biogenesis GO:0070271 201 0.040
cellular response to organic substance GO:0071310 132 0.040
single organism biosynthetic process GO:0044711 206 0.040
regulation of cell cycle phase transition GO:1901987 130 0.040
stem cell differentiation GO:0048863 117 0.040
imaginal disc derived wing morphogenesis GO:0007476 337 0.039
regulation of molecular function GO:0065009 217 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.038
regulation of cellular protein catabolic process GO:1903362 44 0.038
response to organic cyclic compound GO:0014070 89 0.038
negative regulation of protein metabolic process GO:0051248 85 0.037
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.037
protein localization GO:0008104 284 0.037
response to endogenous stimulus GO:0009719 119 0.036
positive regulation of signal transduction GO:0009967 223 0.036
death GO:0016265 284 0.036
mesenchymal cell differentiation GO:0048762 1 0.036
positive regulation of cell proliferation GO:0008284 47 0.035
cellular protein modification process GO:0006464 438 0.035
positive regulation of cellular protein catabolic process GO:1903364 24 0.035
cell death GO:0008219 279 0.034
regulation of synapse structure and activity GO:0050803 128 0.034
negative regulation of response to stimulus GO:0048585 258 0.033
regulation of cell differentiation GO:0045595 302 0.033
larval development GO:0002164 104 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.033
negative regulation of cellular component organization GO:0051129 108 0.033
positive regulation of cellular catabolic process GO:0031331 95 0.033
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.032
appendage development GO:0048736 401 0.032
post embryonic appendage morphogenesis GO:0035120 385 0.032
carboxylic acid metabolic process GO:0019752 92 0.032
embryonic development via the syncytial blastoderm GO:0001700 148 0.031
positive regulation of protein catabolic process GO:0045732 34 0.030
regulation of cytoplasmic transport GO:1903649 47 0.030
compound eye photoreceptor cell differentiation GO:0001751 140 0.030
regulation of meiosis GO:0040020 3 0.030
negative regulation of biosynthetic process GO:0009890 277 0.030
establishment of localization in cell GO:0051649 402 0.030
negative regulation of cellular protein metabolic process GO:0032269 85 0.029
cellular component assembly involved in morphogenesis GO:0010927 151 0.029
response to external biotic stimulus GO:0043207 293 0.029
alternative mrna splicing via spliceosome GO:0000380 60 0.028
cell motility GO:0048870 251 0.028
oxoacid metabolic process GO:0043436 103 0.028
single organism intracellular transport GO:1902582 207 0.028
regulation of cell death GO:0010941 173 0.027
appendage morphogenesis GO:0035107 397 0.027
nucleus organization GO:0006997 45 0.027
regulation of protein stability GO:0031647 43 0.027
body morphogenesis GO:0010171 2 0.027
eye development GO:0001654 323 0.027
regulation of protein complex assembly GO:0043254 42 0.026
protein phosphorylation GO:0006468 169 0.026
regulation of protein modification process GO:0031399 112 0.026
mitotic spindle organization GO:0007052 220 0.026
positive regulation of nucleic acid templated transcription GO:1903508 266 0.026
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.026
rna 3 end processing GO:0031123 45 0.026
negative regulation of transcription dna templated GO:0045892 237 0.025
meiotic nuclear division GO:0007126 151 0.025
regulation of neurogenesis GO:0050767 158 0.025
regulation of mapk cascade GO:0043408 92 0.025
negative regulation of signal transduction GO:0009968 206 0.024
ubiquitin homeostasis GO:0010992 1 0.024
multicellular organismal aging GO:0010259 140 0.024
embryonic morphogenesis GO:0048598 206 0.023
muscle organ development GO:0007517 127 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
organelle assembly GO:0070925 198 0.023
germarium derived egg chamber formation GO:0007293 101 0.022
imaginal disc derived appendage development GO:0048737 399 0.022
response to other organism GO:0051707 293 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
cellular protein localization GO:0034613 160 0.021
chromatin modification GO:0016568 147 0.021
Human
growth GO:0040007 359 0.021
purine nucleoside triphosphate metabolic process GO:0009144 119 0.021
reproductive system development GO:0061458 74 0.020
positive regulation of phosphorylation GO:0042327 87 0.020
regulation of nuclear division GO:0051783 58 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
regulation of locomotion GO:0040012 42 0.020
positive regulation of proteolysis GO:0045862 52 0.020
response to nitrogen compound GO:1901698 90 0.019
leg disc morphogenesis GO:0007478 80 0.019
ncrna metabolic process GO:0034660 43 0.019
positive regulation of signaling GO:0023056 243 0.019
cell aging GO:0007569 2 0.019
positive regulation of intracellular signal transduction GO:1902533 116 0.019
stem cell division GO:0017145 69 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
sister chromatid segregation GO:0000819 92 0.019
small gtpase mediated signal transduction GO:0007264 88 0.018
negative regulation of cell communication GO:0010648 223 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
chromosome segregation GO:0007059 157 0.018
positive regulation of cell communication GO:0010647 250 0.018
wing disc morphogenesis GO:0007472 344 0.017
central nervous system development GO:0007417 201 0.017
positive regulation of lipid metabolic process GO:0045834 4 0.017
ras protein signal transduction GO:0007265 88 0.017
establishment or maintenance of cell polarity GO:0007163 167 0.017
defense response GO:0006952 300 0.017
negative regulation of translation GO:0017148 28 0.017
response to nutrient levels GO:0031667 114 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
microtubule organizing center organization GO:0031023 168 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
negative regulation of signaling GO:0023057 219 0.016
regulation of protein localization GO:0032880 76 0.016
negative regulation of cellular catabolic process GO:0031330 34 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
epithelial cell development GO:0002064 274 0.016
neuron projection guidance GO:0097485 241 0.016
positive regulation of mrna processing GO:0050685 4 0.016
negative regulation of cell death GO:0060548 81 0.016
dna metabolic process GO:0006259 227 0.016
regulation of cellular localization GO:0060341 136 0.016
aromatic compound catabolic process GO:0019439 166 0.015
regulation of protein phosphorylation GO:0001932 64 0.015
positive regulation of molecular function GO:0044093 136 0.015
regulation of transport GO:0051049 181 0.015
ovarian follicle cell development GO:0030707 248 0.015
protein processing GO:0016485 68 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
oocyte differentiation GO:0009994 145 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
organic acid metabolic process GO:0006082 103 0.014
regulation of cell growth GO:0001558 43 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
spliceosomal snrnp assembly GO:0000387 2 0.014
regulation of cell division GO:0051302 72 0.014
stem cell development GO:0048864 79 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
regionalization GO:0003002 416 0.013
heterocycle catabolic process GO:0046700 166 0.013
regulation of neuron differentiation GO:0045664 103 0.013
nucleosome assembly GO:0006334 35 0.013
regulation of cellular response to stress GO:0080135 89 0.013
positive regulation of cell cycle process GO:0090068 28 0.013
protein transport GO:0015031 155 0.013
response to extracellular stimulus GO:0009991 116 0.013
programmed cell death GO:0012501 257 0.013
negative regulation of neuroblast proliferation GO:0007406 27 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
negative regulation of neurogenesis GO:0050768 53 0.013
intracellular protein transport GO:0006886 104 0.013
nuclear envelope organization GO:0006998 7 0.013
positive regulation of cell death GO:0010942 69 0.013
positive regulation of cell cycle GO:0045787 43 0.013
head development GO:0060322 135 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
centrosome organization GO:0051297 163 0.013
telencephalon development GO:0021537 2 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
carbohydrate metabolic process GO:0005975 82 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
secretion by cell GO:0032940 101 0.012
mitotic sister chromatid segregation GO:0000070 87 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.012
regulation of sister chromatid segregation GO:0033045 28 0.012
protein dna complex assembly GO:0065004 63 0.012
synapse assembly GO:0007416 143 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.011
nucleotide metabolic process GO:0009117 161 0.011
regulation of developmental growth GO:0048638 174 0.011
ovarian follicle cell migration GO:0007297 121 0.011
regulation of organelle organization GO:0033043 196 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
regulation of catalytic activity GO:0050790 185 0.011
nuclear transport GO:0051169 72 0.011
trna processing GO:0008033 3 0.011
chromatin assembly GO:0031497 48 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
immune system process GO:0002376 347 0.011
ameboidal type cell migration GO:0001667 151 0.011
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.011
phagocytosis GO:0006909 215 0.011
regulation of transferase activity GO:0051338 58 0.011
segmentation GO:0035282 207 0.011
camera type eye development GO:0043010 4 0.011
photoreceptor cell differentiation GO:0046530 170 0.010
axon development GO:0061564 297 0.010
cell migration GO:0016477 238 0.010
negative regulation of phosphate metabolic process GO:0045936 45 0.010
sex differentiation GO:0007548 81 0.010
positive regulation of growth GO:0045927 75 0.010
regulation of cellular component movement GO:0051270 42 0.010

UbcD2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.083
nervous system disease DOID:863 0 0.030
central nervous system disease DOID:331 0 0.027
neurodegenerative disease DOID:1289 0 0.027
motor neuron disease DOID:231 0 0.027