Homo sapiens

54 known processes

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

(Aliases: PHS-2,PGHS-2,COX2,PGG/HS,COX-2,GRIPGHS,hCox-2)

PTGS2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.977
positive regulation of acute inflammatory response GO:0002675 2 0.959
Mouse Rat
disruption by host of symbiont cells GO:0051852 2 0.953
regulation of camp metabolic process GO:0030814 52 0.929
cyclic nucleotide metabolic process GO:0009187 82 0.919
positive regulation of camp metabolic process GO:0030816 41 0.910
mature natural killer cell chemotaxis GO:0035782 1 0.879
cellular response to endogenous stimulus GO:0071495 336 0.867
Rat
regulation of camp mediated signaling GO:0043949 13 0.866
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 18 0.860
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.855
regulation of killing of cells of other organism GO:0051709 4 0.854
acute inflammatory response GO:0002526 21 0.826
Mouse Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.821
response to organic cyclic compound GO:0014070 204 0.776
Zebrafish Rat
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.747
cellular response to oxygen containing compound GO:1901701 276 0.739
Rat
blood vessel morphogenesis GO:0048514 162 0.715
Rat
neutrophil mediated cytotoxicity GO:0070942 1 0.711
regulation of response to external stimulus GO:0032101 222 0.705
Mouse Rat
positive regulation of homeostatic process GO:0032846 47 0.703
Mouse Rat
vasculature development GO:0001944 181 0.701
Rat
g protein coupled receptor signaling pathway GO:0007186 207 0.695
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.681
response to organonitrogen compound GO:0010243 156 0.666
Rat
response to molecule of bacterial origin GO:0002237 82 0.666
Rat
positive regulation of cell proliferation GO:0008284 301 0.645
Rat
positive regulation of cell differentiation GO:0045597 211 0.638
Mouse
regulation of ion transport GO:0043269 189 0.638
Rat
response to fibroblast growth factor GO:0071774 39 0.631
cell chemotaxis GO:0060326 112 0.631
negative regulation of apoptotic process GO:0043066 316 0.604
viral life cycle GO:0019058 132 0.588
regulation of reactive oxygen species metabolic process GO:2000377 41 0.578
negative regulation of apoptotic signaling pathway GO:2001234 97 0.572
taxis GO:0042330 157 0.571
camp metabolic process GO:0046058 61 0.568
cyclic nucleotide mediated signaling GO:0019935 26 0.566
regulation of cellular component movement GO:0051270 334 0.560
Rat
response to hormone GO:0009725 175 0.555
Rat
blood vessel development GO:0001568 172 0.554
Rat
negative regulation of programmed cell death GO:0043069 321 0.553
regulation of single stranded viral rna replication via double stranded dna intermediate GO:0045091 8 0.533
response to growth factor GO:0070848 205 0.532
cellular divalent inorganic cation homeostasis GO:0072503 128 0.529
erk1 and erk2 cascade GO:0070371 104 0.526
regulation of cell migration GO:0030334 289 0.525
Rat
response to oxygen containing compound GO:1901700 369 0.524
Rat
negative regulation of cell death GO:0060548 345 0.520
response to lipid GO:0033993 206 0.513
Rat
response to biotic stimulus GO:0009607 276 0.511
Rat
response to abiotic stimulus GO:0009628 336 0.507
lymphocyte migration GO:0072676 28 0.505
chemotaxis GO:0006935 157 0.500
regulation of neutrophil mediated cytotoxicity GO:0070948 1 0.498
circulatory system development GO:0072359 262 0.493
Rat
positive regulation of cell motility GO:2000147 177 0.492
Rat
neutrophil mediated immunity GO:0002446 4 0.488
organonitrogen compound biosynthetic process GO:1901566 200 0.486
regulation of erk1 and erk2 cascade GO:0070372 99 0.485
regulation of cell differentiation GO:0045595 393 0.477
Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.476
positive regulation of locomotion GO:0040017 186 0.474
Rat
regulation of angiogenesis GO:0045765 92 0.474
Rat
female gamete generation GO:0007292 2 0.471
Rat
response to nitrogen compound GO:1901698 184 0.471
Rat
mhc class ii biosynthetic process GO:0045342 4 0.470
positive regulation of release of sequestered calcium ion into cytosol GO:0051281 16 0.468
defense response GO:0006952 315 0.467
Mouse Rat
response to estradiol GO:0032355 23 0.463
Rat
positive regulation of developmental process GO:0051094 314 0.460
Mouse Rat
regulation of cytokine production GO:0001817 232 0.454
Rat
mapk cascade GO:0000165 288 0.453
regulation of system process GO:0044057 101 0.449
Rat
regulation of neutrophil mediated killing of symbiont cell GO:0070949 1 0.448
negative regulation of cd4 positive alpha beta t cell proliferation GO:2000562 1 0.446
cytosolic calcium ion homeostasis GO:0051480 89 0.439
positive regulation of macrophage chemotaxis GO:0010759 3 0.435
positive regulation of epithelial cell proliferation GO:0050679 65 0.434
response to bacterium GO:0009617 144 0.428
Rat
regulation of cell motility GO:2000145 299 0.427
Rat
regulation of cellular amine metabolic process GO:0033238 11 0.426
positive regulation of calcium ion transport into cytosol GO:0010524 20 0.421
induction of positive chemotaxis GO:0050930 8 0.412
sodium ion transport GO:0006814 61 0.412
camp mediated signaling GO:0019933 23 0.411
response to cytokine GO:0034097 232 0.409
Rat
luteolysis GO:0001554 3 0.407
negative regulation of lymphocyte chemotaxis GO:1901624 2 0.406
regulation of cell adhesion GO:0030155 166 0.405
positive regulation of response to external stimulus GO:0032103 88 0.402
Mouse Rat
smooth muscle cell proliferation GO:0048659 28 0.402
Rat
chemokine mediated signaling pathway GO:0070098 16 0.398
response to oxidative stress GO:0006979 121 0.390
regulation of response to wounding GO:1903034 101 0.389
Mouse Rat
negative regulation of cell differentiation GO:0045596 171 0.388
calcium ion homeostasis GO:0055074 122 0.382
apoptotic signaling pathway GO:0097190 268 0.382
regulation of chemotaxis GO:0050920 74 0.381
regulation of lymphocyte migration GO:2000401 22 0.381
response to alcohol GO:0097305 64 0.380
Rat
regulation of cell cycle GO:0051726 393 0.375
Rat
tube development GO:0035295 125 0.372
calcium ion transport GO:0006816 147 0.369
Rat
cytokine mediated signaling pathway GO:0019221 109 0.367
cellular response to molecule of bacterial origin GO:0071219 62 0.366
response to interleukin 1 GO:0070555 47 0.365
neutrophil chemotaxis GO:0030593 24 0.356
positive regulation of transport GO:0051050 336 0.355
Rat
response to glucocorticoid GO:0051384 13 0.355
Rat
granulocyte migration GO:0097530 40 0.355
regulation of inflammatory response GO:0050727 46 0.352
Mouse Rat
myeloid dendritic cell chemotaxis GO:0002408 3 0.350
cell adhesion GO:0007155 325 0.350
secretion GO:0046903 254 0.349
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.349
cellular response to growth factor stimulus GO:0071363 197 0.347
positive regulation of t cell migration GO:2000406 13 0.346
negative regulation of c c chemokine binding GO:2001264 1 0.340
amine metabolic process GO:0009308 44 0.333
negative regulation of protein metabolic process GO:0051248 391 0.331
positive regulation of heterotypic cell cell adhesion GO:0034116 8 0.327
cellular chemical homeostasis GO:0055082 180 0.326
immune system development GO:0002520 195 0.326
positive regulation of immune system process GO:0002684 283 0.319
regulation of cell cell adhesion GO:0022407 57 0.318
viral process GO:0016032 146 0.314
positive regulation of superoxide anion generation GO:0032930 4 0.313
positive regulation of ion transport GO:0043270 87 0.311
negative regulation of multicellular organismal process GO:0051241 317 0.310
Rat
leukocyte chemotaxis GO:0030595 76 0.307
multi organism cellular process GO:0044764 156 0.307
positive regulation of cd8 positive alpha beta t cell activation GO:2001187 1 0.306
positive regulation of cell death GO:0010942 263 0.302
Rat
positive regulation of cellular component movement GO:0051272 181 0.302
Rat
response to wounding GO:0009611 168 0.298
Mouse Rat
cellular cation homeostasis GO:0030003 163 0.297
receptor internalization GO:0031623 43 0.297
cation transport GO:0006812 331 0.296
Rat
regulation of nucleotide metabolic process GO:0006140 269 0.296
regulation of mapk cascade GO:0043408 262 0.293
peptidyl tyrosine phosphorylation GO:0018108 170 0.293
positive regulation of apoptotic process GO:0043065 246 0.291
Rat
positive regulation of cd8 positive alpha beta t cell proliferation GO:2000566 1 0.289
inflammatory response GO:0006954 79 0.288
Mouse Rat
negative regulation of cellular protein metabolic process GO:0032269 353 0.284
negative regulation of cell cycle GO:0045786 193 0.282
Rat
leukocyte migration GO:0050900 107 0.278
myeloid cell differentiation GO:0030099 117 0.276
response to lipopolysaccharide GO:0032496 70 0.276
Rat
cytokine production GO:0001816 247 0.273
Rat
neutrophil migration GO:1990266 25 0.272
regulation of apoptotic signaling pathway GO:2001233 175 0.271
positive regulation of programmed cell death GO:0043068 249 0.271
Rat
divalent inorganic cation homeostasis GO:0072507 136 0.270
response to reactive oxygen species GO:0000302 61 0.270
cellular response to lipid GO:0071396 127 0.269
chronic inflammatory response GO:0002544 2 0.268
anatomical structure formation involved in morphogenesis GO:0048646 284 0.267
Rat
myeloid leukocyte migration GO:0097529 62 0.265
endothelial cell migration GO:0043542 86 0.264
Rat
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.263
regulation of locomotion GO:0040012 329 0.263
Rat
sequestering of calcium ion GO:0051208 17 0.262
digestive system development GO:0055123 75 0.259
positive regulation of behavior GO:0048520 60 0.257
regulation of c c chemokine binding GO:2001263 1 0.257
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.256
positive regulation of cell migration GO:0030335 172 0.255
Rat
positive regulation of intracellular protein transport GO:0090316 76 0.254
Rat
positive regulation of defense response GO:0031349 87 0.253
Mouse Rat
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.250
cellular response to interleukin 1 GO:0071347 35 0.250
second messenger mediated signaling GO:0019932 78 0.249
positive regulation of mapk cascade GO:0043410 190 0.248
regulation of leukocyte migration GO:0002685 63 0.247
positive regulation of killing of cells of other organism GO:0051712 4 0.245
cellular response to lipopolysaccharide GO:0071222 57 0.242
negative regulation of myeloid cell differentiation GO:0045638 42 0.241
response to radiation GO:0009314 151 0.239
Rat
cell cycle arrest GO:0007050 71 0.238
positive regulation of nucleotide metabolic process GO:0045981 230 0.233
response to corticosteroid GO:0031960 15 0.231
Rat
regulation of metal ion transport GO:0010959 120 0.231
Rat
eosinophil activation involved in immune response GO:0002278 2 0.230
regulation of cellular amino acid metabolic process GO:0006521 6 0.229
regulation of viral process GO:0050792 103 0.227
granulocyte chemotaxis GO:0071621 37 0.226
ion homeostasis GO:0050801 230 0.226
cellular metal ion homeostasis GO:0006875 146 0.224
metal ion homeostasis GO:0055065 169 0.224
sequestering of metal ion GO:0051238 24 0.222
lymphocyte chemotaxis GO:0048247 17 0.222
positive regulation of chemotaxis GO:0050921 57 0.221
vesicle mediated transport GO:0016192 371 0.219
hematopoietic or lymphoid organ development GO:0048534 186 0.218
cell development GO:0048468 328 0.217
negative regulation of amine transport GO:0051953 1 0.215
nervous system development GO:0007399 293 0.212
positive regulation of homotypic cell cell adhesion GO:0034112 4 0.212
regulation of defense response GO:0031347 154 0.211
Mouse Rat
cellular response to biotic stimulus GO:0071216 71 0.210
cellular homeostasis GO:0019725 196 0.210
chemical homeostasis GO:0048878 306 0.207
negative regulation of mhc class ii biosynthetic process GO:0045347 1 0.207
hemopoiesis GO:0030097 180 0.206
negative regulation of cell proliferation GO:0008285 228 0.205
Rat
response to endoplasmic reticulum stress GO:0034976 49 0.204
regulation of protein import into nucleus GO:0042306 78 0.203
Rat
ameboidal type cell migration GO:0001667 135 0.203
Rat
negative regulation of cytolysis GO:0045918 3 0.197
metal ion transport GO:0030001 272 0.197
Rat
positive regulation of camp mediated signaling GO:0043950 10 0.196
generation of neurons GO:0048699 152 0.195
response to estrogen GO:0043627 47 0.194
Rat
regulation of ion homeostasis GO:2000021 73 0.192
regulation of leukocyte differentiation GO:1902105 61 0.189
positive regulation of granzyme b production GO:0071663 1 0.189
digestive tract development GO:0048565 75 0.189
modification of morphology or physiology of other organism GO:0035821 43 0.184
organic anion transport GO:0015711 103 0.184
cation homeostasis GO:0055080 189 0.182
regulation of homeostatic process GO:0032844 121 0.180
Mouse Rat
regulation of behavior GO:0050795 82 0.180
behavior GO:0007610 112 0.179
Rat
regulation of epithelial cell proliferation GO:0050678 113 0.177
positive regulation of potassium ion transport GO:0043268 15 0.176
organ morphogenesis GO:0009887 147 0.175
interaction with symbiont GO:0051702 26 0.175
cellular ion homeostasis GO:0006873 168 0.174
regulation of granzyme b production GO:0071661 1 0.173
regulation of proteolysis GO:0030162 293 0.171
response to other organism GO:0051707 261 0.170
Rat
muscle cell proliferation GO:0033002 35 0.170
Rat
response to gamma radiation GO:0010332 14 0.170
disruption of cells of other organism involved in symbiotic interaction GO:0051818 3 0.169
regulation of intracellular transport GO:0032386 195 0.168
Rat
divalent inorganic cation transport GO:0072511 158 0.167
Rat
embryonic digestive tract development GO:0048566 10 0.167
positive regulation of catabolic process GO:0009896 310 0.164
regulation of dna metabolic process GO:0051052 153 0.164
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.163
negative regulation of phosphate metabolic process GO:0045936 267 0.163
t cell migration GO:0072678 16 0.162
enzyme linked receptor protein signaling pathway GO:0007167 303 0.159
killing by host of symbiont cells GO:0051873 2 0.159
regulation of smooth muscle cell proliferation GO:0048660 28 0.158
Rat
positive regulation of t cell apoptotic process GO:0070234 4 0.156
regulation of vasculature development GO:1901342 97 0.155
Rat
system process GO:0003008 349 0.154
Mouse Rat
response to external biotic stimulus GO:0043207 261 0.154
Rat
regulation of endothelial cell proliferation GO:0001936 56 0.154
response to metal ion GO:0010038 84 0.152
Rat
negative regulation of developmental process GO:0051093 247 0.151
cellular calcium ion homeostasis GO:0006874 117 0.150
negative regulation of phosphorus metabolic process GO:0010563 267 0.149
disruption of cells of other organism GO:0044364 7 0.149
positive regulation of myosin light chain kinase activity GO:0035505 1 0.149
granzyme b production GO:0071613 1 0.148
response to inorganic substance GO:0010035 127 0.148
Rat
intrinsic apoptotic signaling pathway GO:0097193 127 0.148
negative regulation of catalytic activity GO:0043086 335 0.147
cellular amine metabolic process GO:0044106 41 0.144
cytoplasmic transport GO:0016482 379 0.144
Rat
single organism cell adhesion GO:0098602 179 0.143
modification by host of symbiont morphology or physiology GO:0051851 26 0.143
angiogenesis GO:0001525 147 0.141
Rat
regulation of calcium ion transport into cytosol GO:0010522 33 0.141
negative regulation of chemokine mediated signaling pathway GO:0070100 5 0.139
reactive oxygen species metabolic process GO:0072593 75 0.139
maintenance of location GO:0051235 112 0.139
positive regulation of endothelial cell proliferation GO:0001938 37 0.138
nitrogen compound transport GO:0071705 191 0.138
Rat
regulation of heterotypic cell cell adhesion GO:0034114 14 0.137
calcium ion transport into cytosol GO:0060402 48 0.137
blood circulation GO:0008015 113 0.136
Mouse Rat
post embryonic development GO:0009791 2 0.136
locomotory behavior GO:0007626 1 0.135
t cell chemotaxis GO:0010818 10 0.134
cellular response to cytokine stimulus GO:0071345 181 0.134
positive regulation of cytoplasmic transport GO:1903651 82 0.133
Rat
response to fungus GO:0009620 4 0.133
regulation of myeloid cell differentiation GO:0045637 81 0.132
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.132
cellular response to hormone stimulus GO:0032870 125 0.131
regulation of acute inflammatory response GO:0002673 13 0.131
Mouse Rat
epithelium migration GO:0090132 119 0.131
Rat
cellular amino acid metabolic process GO:0006520 116 0.131
eosinophil degranulation GO:0043308 2 0.129
regulation of cytoplasmic transport GO:1903649 149 0.129
Rat
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.128
regulation of neutrophil chemotaxis GO:0090022 10 0.125
divalent metal ion transport GO:0070838 152 0.125
Rat
tissue morphogenesis GO:0048729 96 0.125
lipid metabolic process GO:0006629 381 0.125
cd8 positive alpha beta t cell activation GO:0036037 3 0.124
positive regulation of stress activated mapk cascade GO:0032874 60 0.124
cardiovascular system development GO:0072358 262 0.119
Rat
lipid biosynthetic process GO:0008610 177 0.119
defense response to fungus GO:0050832 4 0.119
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.118
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.118
neurological system process GO:0050877 163 0.118
Rat
positive regulation of sodium ion transport GO:0010765 14 0.117
regulation of purine nucleotide metabolic process GO:1900542 264 0.117
negative regulation of multicellular organismal metabolic process GO:0044252 3 0.116
ribonucleotide catabolic process GO:0009261 405 0.116
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.114
chemokine metabolic process GO:0050755 4 0.114
response to ionizing radiation GO:0010212 65 0.113
hemostasis GO:0007599 76 0.113
positive regulation of leukocyte migration GO:0002687 46 0.113
positive regulation of positive chemotaxis GO:0050927 13 0.113
peptide hormone secretion GO:0030072 50 0.112
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.112
regulation of mononuclear cell proliferation GO:0032944 65 0.111
negative regulation of neuron apoptotic process GO:0043524 23 0.110
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.110
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.110
receptor metabolic process GO:0043112 81 0.110
regulation of rho protein signal transduction GO:0035023 79 0.110
regeneration GO:0031099 4 0.109
positive regulation of phosphorylation GO:0042327 394 0.109
regulation of cellular ketone metabolic process GO:0010565 50 0.106
superoxide metabolic process GO:0006801 20 0.104
cell cell signaling GO:0007267 155 0.104
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.103
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.103
endocytosis GO:0006897 159 0.102
response to calcium ion GO:0051592 46 0.102
mitotic nuclear division GO:0007067 119 0.101
release of sequestered calcium ion into cytosol GO:0051209 41 0.101
rna replication GO:0039703 9 0.101
positive regulation of intracellular transport GO:0032388 104 0.101
Rat
icosanoid transport GO:0071715 11 0.100
cell activation GO:0001775 213 0.100
cellular response to tumor necrosis factor GO:0071356 63 0.099
positive regulation of calcium ion transport GO:0051928 51 0.099
blood coagulation GO:0007596 76 0.099
positive regulation of cellular component organization GO:0051130 376 0.099
negative regulation of protein modification process GO:0031400 200 0.098
regulation of protein kinase activity GO:0045859 289 0.098
multi organism metabolic process GO:0044033 41 0.097
negative regulation of lymphocyte migration GO:2000402 4 0.097
regulation of sequestering of calcium ion GO:0051282 41 0.097
negative regulation of protein processing GO:0010955 142 0.097
interspecies interaction between organisms GO:0044419 156 0.096
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.095
positive regulation of natural killer cell chemotaxis GO:2000503 5 0.095
regulation of protein processing GO:0070613 150 0.095
regulation of cell cycle process GO:0010564 266 0.094
wound healing GO:0042060 115 0.094
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.094
neurogenesis GO:0022008 169 0.093
regulation of interleukin 1 mediated signaling pathway GO:2000659 3 0.093
negative regulation of homeostatic process GO:0032845 59 0.093
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.093
regulation of viral genome replication GO:0045069 48 0.093
biological adhesion GO:0022610 331 0.092
embryo development GO:0009790 123 0.092
response to fatty acid GO:0070542 13 0.091
Rat
positive regulation of jak stat cascade GO:0046427 35 0.089
regulation of multi organism process GO:0043900 157 0.089
regulation of map kinase activity GO:0043405 108 0.087
regulation of kinase activity GO:0043549 314 0.087
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.087
negative regulation of map kinase activity GO:0043407 27 0.087
regulation of t cell activation GO:0050863 77 0.087
response to organophosphorus GO:0046683 41 0.086
Rat
single organismal cell cell adhesion GO:0016337 148 0.085
regulation of leukocyte activation GO:0002694 115 0.085
regulation of t cell migration GO:2000404 14 0.085
positive regulation of t cell differentiation GO:0045582 11 0.084
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.084
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.084
Rat
positive regulation of myeloid cell differentiation GO:0045639 39 0.083
intracellular protein transport GO:0006886 270 0.083
Rat
developmental programmed cell death GO:0010623 3 0.082
purine ribonucleoside metabolic process GO:0046128 437 0.082
regulation of macrophage chemotaxis GO:0010758 4 0.081
signal transduction by phosphorylation GO:0023014 297 0.081
cytokine biosynthetic process GO:0042089 37 0.080
protein localization to organelle GO:0033365 280 0.080
Rat
monocyte aggregation GO:0070487 4 0.080
hematopoietic progenitor cell differentiation GO:0002244 38 0.080
leukocyte differentiation GO:0002521 98 0.080
regulation of release of sequestered calcium ion into cytosol GO:0051279 27 0.080
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.080
organophosphate catabolic process GO:0046434 430 0.080
regulation of leukocyte proliferation GO:0070663 67 0.079
regulation of protein transport GO:0051223 213 0.079
Rat
regulation of response to biotic stimulus GO:0002831 55 0.079
response to hypoxia GO:0001666 96 0.079
regulation of anatomical structure morphogenesis GO:0022603 286 0.078
Rat
regulation of cellular response to stress GO:0080135 244 0.078
negative regulation of intracellular signal transduction GO:1902532 183 0.077
regulation of secretion by cell GO:1903530 177 0.077
rho protein signal transduction GO:0007266 26 0.076
regulation of neuron death GO:1901214 56 0.076
reactive oxygen species biosynthetic process GO:1903409 4 0.076
regulation of secretion GO:0051046 194 0.076
positive regulation of organic acid transport GO:0032892 3 0.076
regulation of nucleocytoplasmic transport GO:0046822 98 0.076
Rat
positive regulation of protein import into nucleus GO:0042307 46 0.076
Rat
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.076
small gtpase mediated signal transduction GO:0007264 78 0.075
protein catabolic process GO:0030163 325 0.075
regulation of transferase activity GO:0051338 355 0.074
positive regulation of gliogenesis GO:0014015 4 0.073
jnk cascade GO:0007254 80 0.071
regulation of t cell chemotaxis GO:0010819 7 0.071
defense response to other organism GO:0098542 129 0.071
negative regulation of transferase activity GO:0051348 124 0.071
neuron development GO:0048666 113 0.071
mitotic cell cycle process GO:1903047 286 0.071
cytosolic calcium ion transport GO:0060401 48 0.071
negative regulation of collagen metabolic process GO:0010713 3 0.070
regulation of potassium ion transport GO:0043266 24 0.070
neuron death GO:0070997 65 0.069
protein maturation GO:0051604 233 0.069
endothelial cell proliferation GO:0001935 65 0.069
regulation of positive chemotaxis GO:0050926 14 0.069
positive regulation of cell adhesion GO:0045785 84 0.069
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.069
Rat
ras protein signal transduction GO:0007265 73 0.069
positive regulation of multi organism process GO:0043902 56 0.068
immune response GO:0006955 307 0.068
positive regulation of cytokine production GO:0001819 167 0.068
Rat
regulation of neuron apoptotic process GO:0043523 35 0.068
arachidonic acid metabolic process GO:0019369 14 0.067
regulation of protein localization GO:0032880 296 0.066
Rat
mitotic cell cycle GO:0000278 326 0.066
regulation of hormone levels GO:0010817 125 0.066
response to camp GO:0051591 25 0.066
killing of cells in other organism involved in symbiotic interaction GO:0051883 3 0.065
viral rna genome replication GO:0039694 9 0.065
regulation of chemokine biosynthetic process GO:0045073 4 0.064
negative regulation of protein binding GO:0032091 35 0.064
positive chemotaxis GO:0050918 33 0.064
positive regulation of myeloid leukocyte mediated immunity GO:0002888 1 0.064
protein kinase b signaling GO:0043491 69 0.063
lipid transport GO:0006869 90 0.063
regulation of granulocyte chemotaxis GO:0071622 16 0.063
leukocyte aggregation GO:0070486 8 0.063
purine nucleoside triphosphate metabolic process GO:0009144 412 0.062
response to toxic substance GO:0009636 37 0.062
cellular ketone metabolic process GO:0042180 80 0.062
negative regulation of protein phosphorylation GO:0001933 140 0.061
regulation of establishment of protein localization GO:0070201 242 0.061
Rat
epithelial cell migration GO:0010631 119 0.061
Rat
macrophage chemotaxis GO:0048246 10 0.061
positive regulation of mononuclear cell proliferation GO:0032946 47 0.060
regulation of leukocyte mediated immunity GO:0002703 38 0.060
regulation of mitotic cell cycle GO:0007346 189 0.059
glycosyl compound catabolic process GO:1901658 413 0.059
regulation of cell killing GO:0031341 22 0.059
regulation of stem cell proliferation GO:0072091 15 0.059
positive regulation of jnk cascade GO:0046330 52 0.057
regulation of calcium ion transport GO:0051924 79 0.057
Rat
regulation of cell activation GO:0050865 125 0.057
positive regulation of lymphocyte migration GO:2000403 16 0.057
membrane organization GO:0061024 292 0.057
response to purine containing compound GO:0014074 40 0.057
Rat
cell growth GO:0016049 160 0.056
regulation of protein serine threonine kinase activity GO:0071900 179 0.056
cellular component morphogenesis GO:0032989 314 0.056
positive regulation of icosanoid secretion GO:0032305 3 0.056
multicellular organismal aging GO:0010259 3 0.055
leukocyte activation GO:0045321 164 0.055
negative regulation of protein maturation GO:1903318 142 0.054
tissue migration GO:0090130 119 0.054
Rat
response to hyperoxia GO:0055093 4 0.054
establishment of lymphocyte polarity GO:0001767 2 0.054
response to steroid hormone GO:0048545 80 0.054
Rat
acute phase response GO:0006953 5 0.054
Mouse Rat
regulation of mitosis GO:0007088 63 0.053
leukocyte apoptotic process GO:0071887 31 0.053
amide transport GO:0042886 76 0.053
Rat
regulation of nuclear division GO:0051783 65 0.053
cell projection organization GO:0030030 252 0.053
salivary gland morphogenesis GO:0007435 4 0.052
response to temperature stimulus GO:0009266 22 0.052
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.052
response to nutrient levels GO:0031667 81 0.051
Rat
neutrophil mediated killing of symbiont cell GO:0070943 1 0.051
cellular response to organonitrogen compound GO:0071417 124 0.051
Rat
cellular response to organic cyclic compound GO:0071407 127 0.051
Zebrafish Rat
cellular response to antibiotic GO:0071236 1 0.051
regulation of t cell proliferation GO:0042129 42 0.051
positive regulation of cell cell adhesion GO:0022409 22 0.051
negative regulation of cell adhesion GO:0007162 64 0.050
nucleotide catabolic process GO:0009166 408 0.050
positive regulation of peptidyl serine phosphorylation of stat protein GO:0033141 3 0.050
nuclear division GO:0000280 128 0.050
aminoglycan metabolic process GO:0006022 39 0.050
protein processing GO:0016485 226 0.050

PTGS2 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.345
disease of cellular proliferation DOID:14566 174 0.345
organ system cancer DOID:0050686 164 0.114