|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.985
|
|
|
|
positive regulation of mesenchymal stem cell proliferation
|
GO:1902462 |
1 |
0.978
|
Human |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.977
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.977
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.968
|
Human |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.963
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.957
|
Human |
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.956
|
Human |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.953
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.947
|
Human |
|
|
positive regulation of mesenchymal stem cell differentiation
|
GO:2000741 |
4 |
0.940
|
Human |
|
|
ossification
|
GO:0001503 |
121 |
0.934
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.927
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.925
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.922
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.914
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.900
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.887
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.884
|
Worm |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.882
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.870
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.870
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.844
|
Worm |
|
|
mesenchymal stem cell proliferation
|
GO:0097168 |
1 |
0.836
|
Human |
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.824
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.823
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.818
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.787
|
|
|
|
regulation of mesenchymal stem cell proliferation
|
GO:1902460 |
1 |
0.775
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.764
|
Human |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.749
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.744
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.741
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.728
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.728
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.689
|
Zebrafish |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.680
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.679
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.674
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.674
|
Human |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.663
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.646
|
Zebrafish |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.644
|
|
|
|
positive regulation of epithelial cell proliferation involved in wound healing
|
GO:0060054 |
3 |
0.641
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.639
|
Zebrafish Mouse Worm |
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.638
|
Human |
|
|
elastic fiber assembly
|
GO:0048251 |
3 |
0.628
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.627
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.626
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.623
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.616
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.609
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.595
|
|
|
|
regulation of chondrocyte differentiation
|
GO:0032330 |
9 |
0.586
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.575
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.574
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.574
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.558
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.551
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.546
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.528
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.502
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.485
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.485
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.479
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.478
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.468
|
Human |
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.459
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.456
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
17 |
0.446
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.445
|
|
|
|
negative regulation of chondrocyte differentiation
|
GO:0032331 |
5 |
0.440
|
Human |
|
|
connective tissue development
|
GO:0061448 |
39 |
0.435
|
Human |
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.434
|
Zebrafish Mouse Worm |
|
|
osteoblast proliferation
|
GO:0033687 |
8 |
0.433
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.430
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.426
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.423
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.422
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.417
|
|
|
|
positive regulation of osteoblast proliferation
|
GO:0033690 |
3 |
0.411
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.408
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.400
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.393
|
Zebrafish |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.392
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.384
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.378
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.377
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.371
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.369
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.364
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.361
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.360
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.355
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.352
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.339
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.336
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.330
|
|
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.330
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.325
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.322
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.321
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.307
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.304
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.296
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.296
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.292
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.291
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.290
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.290
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.287
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.285
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.283
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.281
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.277
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.277
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.276
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.269
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.268
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.268
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.266
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.266
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.264
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.258
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.257
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.256
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.254
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.253
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.245
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
10 |
0.237
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.233
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.233
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.232
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.229
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.223
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.223
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.222
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.217
|
|
|
|
negative regulation of cartilage development
|
GO:0061037 |
5 |
0.215
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.211
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.209
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.204
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.203
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.203
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.202
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.202
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.200
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.200
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.197
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.190
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.186
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.185
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.183
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.183
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.183
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.181
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.180
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.179
|
Human Mouse |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.177
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.176
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.176
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.175
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.173
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.173
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.173
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.172
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.172
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.171
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.171
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.171
|
|
|
|
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation
|
GO:0044338 |
2 |
0.169
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.169
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.168
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.167
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.166
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.164
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.164
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.159
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.158
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.156
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.154
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.153
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.150
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.150
|
|
|
|
transforming growth factor beta activation
|
GO:0036363 |
1 |
0.150
|
Human |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.149
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.149
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.146
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.145
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.145
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.144
|
Human |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.143
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.143
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.142
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.141
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.139
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.139
|
|
|
|
negative regulation of endothelial cell chemotaxis
|
GO:2001027 |
4 |
0.136
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.135
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.135
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.135
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.133
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.131
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.131
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.131
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.130
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.128
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.128
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.128
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.127
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.127
|
Human |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.127
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
24 |
0.127
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.123
|
|
|
|
myoblast differentiation
|
GO:0045445 |
21 |
0.121
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.121
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.120
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.119
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.119
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.119
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.116
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.116
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.115
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.113
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.113
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.113
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.112
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.112
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.111
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.111
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.111
|
Zebrafish |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.110
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.110
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.110
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.108
|
|
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.108
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.107
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.107
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.105
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.105
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.105
|
Zebrafish |
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.102
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.102
|
|
|
|
heart valve formation
|
GO:0003188 |
2 |
0.102
|
|
|
|
growth
|
GO:0040007 |
202 |
0.101
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.100
|
|
|
|
spemann organizer formation
|
GO:0060061 |
1 |
0.097
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.096
|
|
|
|
negative regulation of granulocyte chemotaxis
|
GO:0071623 |
2 |
0.096
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.096
|
Zebrafish |
|
|
oogenesis
|
GO:0048477 |
2 |
0.096
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.095
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.095
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.094
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.093
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.093
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.093
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.092
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.092
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.091
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.091
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.091
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.090
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.089
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.089
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.089
|
|
|
|
non canonical wnt signaling pathway via mapk cascade
|
GO:0038030 |
4 |
0.089
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.088
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.087
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.086
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.085
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.084
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.083
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.083
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.083
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.083
|
|
|
|
corticospinal tract morphogenesis
|
GO:0021957 |
1 |
0.081
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.081
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.080
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.080
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.080
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.079
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.079
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.078
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.078
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.078
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.077
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.077
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.077
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.076
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.076
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.076
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.075
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.074
|
|
|
|
odontogenesis
|
GO:0042476 |
25 |
0.074
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.074
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.074
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.073
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.073
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.071
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.071
|
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.071
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.071
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.071
|
|
|
|
negative regulation of insulin like growth factor receptor signaling pathway
|
GO:0043569 |
4 |
0.070
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.070
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.070
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.069
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.069
|
|
|
|
canonical wnt signaling pathway involved in osteoblast differentiation
|
GO:0044339 |
2 |
0.069
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.069
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.068
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.068
|
|
|
|
system process
|
GO:0003008 |
349 |
0.066
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.066
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.066
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.066
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.065
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.065
|
|
|
|
transforming growth factor beta production
|
GO:0071604 |
14 |
0.065
|
Human |
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.064
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.064
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.064
|
|
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.063
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.062
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.061
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.061
|
|
|
|
negative regulation of stem cell differentiation
|
GO:2000737 |
22 |
0.060
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.060
|
|
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.060
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.060
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.060
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.059
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.059
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.059
|
|
|
|
regulation of osteoblast proliferation
|
GO:0033688 |
8 |
0.059
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.058
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.058
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.058
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.057
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.057
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.057
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.057
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.057
|
Zebrafish |
|
|
regulation of myotube differentiation
|
GO:0010830 |
18 |
0.055
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.055
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.055
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.055
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.054
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.054
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.054
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.054
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.053
|
|
|
|
induction of negative chemotaxis
|
GO:0050929 |
1 |
0.053
|
|
|
|
oligodendrocyte development
|
GO:0014003 |
6 |
0.053
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.052
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.052
|
|
|
|
limb development
|
GO:0060173 |
23 |
0.052
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.052
|
|
|
|
spinal cord dorsal ventral patterning
|
GO:0021513 |
2 |
0.051
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.051
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.051
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.051
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.050
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.050
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.050
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.050
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.050
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.050
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.049
|
Rat |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.049
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.048
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.048
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.048
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.048
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.047
|
Zebrafish |
|
|
heart development
|
GO:0007507 |
95 |
0.047
|
Zebrafish |
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.047
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.047
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.047
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.047
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.046
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.046
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.046
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.046
|
|
|
|
muscle fiber development
|
GO:0048747 |
16 |
0.046
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.045
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.045
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.045
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.045
|
|
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.045
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.044
|
|
|
|
negative regulation of leukocyte migration
|
GO:0002686 |
14 |
0.044
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.044
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.044
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
12 |
0.044
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.044
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.044
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.044
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.043
|
|
|
|
notch signaling involved in heart development
|
GO:0061314 |
2 |
0.043
|
|
|
|
axis specification
|
GO:0009798 |
12 |
0.042
|
|
|
|
cell aggregation
|
GO:0098743 |
1 |
0.042
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.042
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.042
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.042
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.042
|
Rat |
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.041
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.041
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.041
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.041
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.041
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.041
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.041
|
|
|
|
negative regulation of smooth muscle cell migration
|
GO:0014912 |
7 |
0.041
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.041
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.041
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.040
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.040
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.040
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.040
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.040
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.039
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.039
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.039
|
|
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.038
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.038
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.038
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.038
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.037
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.037
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.037
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.037
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.037
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.037
|
|
|
|
cartilage condensation
|
GO:0001502 |
1 |
0.037
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.037
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.036
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.035
|
|
|
|
proteoglycan metabolic process
|
GO:0006029 |
29 |
0.035
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.035
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.035
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.035
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.035
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.035
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.035
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
26 |
0.035
|
|
|
|
anatomical structure regression
|
GO:0060033 |
1 |
0.035
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.034
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.034
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.034
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.034
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.034
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.034
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.034
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.034
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.034
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.033
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
14 |
0.033
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.033
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.033
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.033
|
|
|
|
positive regulation of cell cell adhesion
|
GO:0022409 |
22 |
0.033
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.033
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
12 |
0.033
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.033
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.033
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.033
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.033
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.032
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.032
|
|
|
|
aortic valve development
|
GO:0003176 |
3 |
0.032
|
|
|
|
regulation of lipoprotein metabolic process
|
GO:0050746 |
7 |
0.032
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.032
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.032
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.032
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.032
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.032
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.032
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.031
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.031
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.031
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.031
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.031
|
|
|
|
regulation of sodium dependent phosphate transport
|
GO:2000118 |
2 |
0.031
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.031
|
|
|
|
retinoid metabolic process
|
GO:0001523 |
18 |
0.031
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.031
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.031
|
|
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.030
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.030
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.030
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.030
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.030
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.030
|
|
