Homo sapiens

113 known processes

XIAP

X-linked inhibitor of apoptosis

(Aliases: XLP2,MIHA,hIAP3,FLJ26913,API3,hIAP-3,ILP1,BIRC4,IAP-3)

XIAP biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein polyubiquitination GO:0000209 110 1.000
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 1.000
Human
protein modification by small protein conjugation GO:0032446 342 1.000
i kappab kinase nf kappab signaling GO:0007249 166 1.000
Human
protein k48 linked ubiquitination GO:0070936 38 1.000
Human
modification dependent protein catabolic process GO:0019941 209 1.000
Human
ubiquitin dependent protein catabolic process GO:0006511 206 1.000
Human
protein ubiquitination GO:0016567 314 1.000
proteolysis involved in cellular protein catabolic process GO:0051603 244 1.000
Human
cellular macromolecule catabolic process GO:0044265 380 1.000
Human
regulation of i kappab kinase nf kappab signaling GO:0043122 162 1.000
Human
regulation of peptidase activity GO:0052547 180 1.000
cellular protein catabolic process GO:0044257 261 1.000
Human
regulation of cysteine type endopeptidase activity GO:2000116 127 1.000
negative regulation of cell death GO:0060548 345 0.999
regulation of proteolysis GO:0030162 293 0.999
positive regulation of apoptotic signaling pathway GO:2001235 70 0.999
regulation of endopeptidase activity GO:0052548 170 0.999
negative regulation of programmed cell death GO:0043069 321 0.999
apoptotic signaling pathway GO:0097190 268 0.999
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 9 0.998
trail activated apoptotic signaling pathway GO:0036462 4 0.998
negative regulation of apoptotic process GO:0043066 316 0.997
regulation of cell cycle GO:0051726 393 0.997
Human
regulation of apoptotic signaling pathway GO:2001233 175 0.997
protein autoubiquitination GO:0051865 37 0.997
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.997
regulation of macrophage differentiation GO:0045649 9 0.997
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.996
protein catabolic process GO:0030163 325 0.995
Human
positive regulation of cell death GO:0010942 263 0.995
extrinsic apoptotic signaling pathway GO:0097191 119 0.995
protein processing GO:0016485 226 0.994
signal transduction involved in mitotic cell cycle checkpoint GO:0072413 13 0.993
positive regulation of proteolysis GO:0045862 142 0.993
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.990
modification dependent macromolecule catabolic process GO:0043632 212 0.990
Human
positive regulation of macrophage differentiation GO:0045651 7 0.989
cellular modified amino acid catabolic process GO:0042219 4 0.989
cardiac right ventricle morphogenesis GO:0003215 3 0.988
cellular response to dna damage stimulus GO:0006974 379 0.987
positive regulation of programmed cell death GO:0043068 249 0.985
cardiovascular system development GO:0072358 262 0.985
g1 dna damage checkpoint GO:0044783 18 0.983
negative regulation of catalytic activity GO:0043086 335 0.981
negative regulation of apoptotic signaling pathway GO:2001234 97 0.977
negative regulation of endopeptidase activity GO:0010951 84 0.976
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.974
positive regulation of peptidase activity GO:0010952 88 0.974
negative regulation of protein processing GO:0010955 142 0.973
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 13 0.968
positive regulation of myeloid cell differentiation GO:0045639 39 0.967
response to external biotic stimulus GO:0043207 261 0.966
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.966
positive regulation of cell cycle GO:0045787 140 0.964
negative regulation of protein maturation GO:1903318 142 0.964
negative regulation of peptidase activity GO:0010466 91 0.961
positive regulation of cell cycle arrest GO:0071158 23 0.956
heart development GO:0007507 95 0.954
response to biotic stimulus GO:0009607 276 0.954
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.954
protein maturation GO:0051604 233 0.953
mitotic dna damage checkpoint GO:0044773 28 0.953
neural tube formation GO:0001841 3 0.952
negative regulation of protein metabolic process GO:0051248 391 0.951
positive regulation of apoptotic process GO:0043065 246 0.950
cell type specific apoptotic process GO:0097285 125 0.946
Human Mouse Rat
intrinsic apoptotic signaling pathway GO:0097193 127 0.946
regulation of cell cycle arrest GO:0071156 36 0.945
cellular response to abiotic stimulus GO:0071214 117 0.941
signal transduction involved in mitotic g1 dna damage checkpoint GO:0072431 10 0.937
protein linear polyubiquitination GO:0097039 5 0.936
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.935
response to lipopolysaccharide GO:0032496 70 0.931
spinal cord development GO:0021510 4 0.929
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.928
Human
activation of cysteine type endopeptidase activity GO:0097202 57 0.926
mitotic g1 s transition checkpoint GO:0044819 17 0.923
proteasomal protein catabolic process GO:0010498 176 0.923
Human
execution phase of apoptosis GO:0097194 32 0.916
regulation of mitotic cell cycle GO:0007346 189 0.914
aortic valve development GO:0003176 3 0.908
regulation of cell cycle process GO:0010564 266 0.907
positive regulation of immune system process GO:0002684 283 0.906
response to lipid GO:0033993 206 0.904
regulation of protein linear polyubiquitination GO:1902528 2 0.904
protein monoubiquitination GO:0006513 39 0.903
Human
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.899
apoptotic mitochondrial changes GO:0008637 57 0.895
negative regulation of proteolysis GO:0045861 132 0.894
midbrain development GO:0030901 45 0.893
mapk cascade GO:0000165 288 0.893
regulation of leukocyte differentiation GO:1902105 61 0.889
zymogen activation GO:0031638 70 0.888
mitotic g1 dna damage checkpoint GO:0031571 17 0.887
positive regulation of protein ubiquitination GO:0031398 53 0.886
positive regulation of neuron apoptotic process GO:0043525 8 0.880
regulation of myeloid cell differentiation GO:0045637 81 0.880
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.876
keratinocyte differentiation GO:0030216 36 0.870
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 10 0.868
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.860
regulation of protein maturation GO:1903317 150 0.860
cellular response to mechanical stimulus GO:0071260 39 0.860
regulation of cell cycle phase transition GO:1901987 126 0.860
signal transduction involved in cell cycle checkpoint GO:0072395 16 0.858
myeloid cell differentiation GO:0030099 117 0.839
positive regulation of endopeptidase activity GO:0010950 84 0.838
myeloid leukocyte differentiation GO:0002573 60 0.838
cardiac ventricle formation GO:0003211 2 0.831
positive regulation of cell fate specification GO:0042660 2 0.821
cardiac vascular smooth muscle cell differentiation GO:0060947 2 0.819
response to bacterium GO:0009617 144 0.816
negative regulation of cell cycle phase transition GO:1901988 89 0.809
response to abiotic stimulus GO:0009628 336 0.805
negative regulation of immune system process GO:0002683 136 0.804
regulation of cellular response to stress GO:0080135 244 0.804
response to oxygen containing compound GO:1901700 369 0.799
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.798
innate immune response GO:0045087 178 0.798
response to cytokine GO:0034097 232 0.797
dna damage checkpoint GO:0000077 68 0.796
signal transduction by p53 class mediator GO:0072331 72 0.793
mitotic cell cycle GO:0000278 326 0.782
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.781
notch signaling involved in heart development GO:0061314 2 0.779
mitotic cell cycle phase transition GO:0044772 162 0.779
circulatory system development GO:0072359 262 0.778
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.769
positive regulation of protein monoubiquitination GO:1902527 1 0.766
Human
forebrain development GO:0030900 26 0.760
regulation of cell cycle g1 s phase transition GO:1902806 42 0.759
cell cycle checkpoint GO:0000075 117 0.759
regulation of protein polyubiquitination GO:1902914 8 0.758
positive regulation of protein k48 linked ubiquitination GO:1902524 1 0.756
Human
cardiac right ventricle formation GO:0003219 1 0.752
response to molecule of bacterial origin GO:0002237 82 0.750
negative regulation of cell cycle process GO:0010948 121 0.747
dna integrity checkpoint GO:0031570 71 0.744
cellular response to oxygen containing compound GO:1901701 276 0.737
cellular response to lipid GO:0071396 127 0.732
immune system development GO:0002520 195 0.731
epithelial cell differentiation GO:0030855 141 0.727
erythrocyte differentiation GO:0030218 28 0.723
hemopoiesis GO:0030097 180 0.718
response to uv GO:0009411 73 0.716
regulation of canonical wnt signaling pathway GO:0060828 88 0.715
cell cycle arrest GO:0007050 71 0.703
endocardial cushion development GO:0003197 3 0.701
regulation of response to dna damage stimulus GO:2001020 94 0.697
positive regulation of cell differentiation GO:0045597 211 0.690
urogenital system development GO:0001655 65 0.681
response to radiation GO:0009314 151 0.676
epithelial tube morphogenesis GO:0060562 38 0.672
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003256 3 0.668
regulation of kinase activity GO:0043549 314 0.667
regulation of protein monoubiquitination GO:1902525 1 0.666
Human
cellular response to endogenous stimulus GO:0071495 336 0.655
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.653
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.651
cell cycle g1 s phase transition GO:0044843 80 0.633
regulation of transferase activity GO:0051338 355 0.625
negative regulation of phosphate metabolic process GO:0045936 267 0.624
coenzyme metabolic process GO:0006732 65 0.622
release of cytochrome c from mitochondria GO:0001836 35 0.621
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.621
negative regulation of humoral immune response GO:0002921 7 0.617
mitotic dna integrity checkpoint GO:0044774 30 0.616
regulation of necroptotic process GO:0060544 7 0.614
Human
tube morphogenesis GO:0035239 95 0.609
negative regulation of phosphorus metabolic process GO:0010563 267 0.603
defense response GO:0006952 315 0.599
cell differentiation in spinal cord GO:0021515 1 0.587
regulation of mitotic cell cycle phase transition GO:1901990 118 0.578
mitotic cell cycle checkpoint GO:0007093 68 0.573
signal transduction in response to dna damage GO:0042770 57 0.568
positive regulation of neuron death GO:1901216 14 0.558
wnt signaling pathway GO:0016055 156 0.553
regulation of wnt signaling pathway GO:0030111 123 0.549
mononuclear cell proliferation GO:0032943 71 0.544
cardiac chamber formation GO:0003207 2 0.539
cell cycle phase transition GO:0044770 173 0.535
regulation of response to external stimulus GO:0032101 222 0.525
response to tumor necrosis factor GO:0034612 76 0.522
signal transduction involved in dna damage checkpoint GO:0072422 15 0.520
regulation of mesodermal cell fate specification GO:0042661 2 0.520
cellular amino acid catabolic process GO:0009063 31 0.518
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.514
cellular response to uv GO:0034644 32 0.512
posttranscriptional regulation of gene expression GO:0010608 213 0.511
response to hormone GO:0009725 175 0.509
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.507
negative regulation of mitotic cell cycle GO:0045930 102 0.499
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.498
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.496
signal transduction involved in mitotic dna damage checkpoint GO:1902402 13 0.490
positive regulation of developmental process GO:0051094 314 0.484
positive regulation of cell cycle process GO:0090068 106 0.479
leukocyte activation GO:0045321 164 0.471
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.469
cellular response to external stimulus GO:0071496 111 0.467
response to other organism GO:0051707 261 0.464
anterior posterior axis specification GO:0009948 2 0.461
distal tubule development GO:0072017 4 0.458
neural nucleus development GO:0048857 47 0.455
regulation of neuron apoptotic process GO:0043523 35 0.454
Rat
response to cobalt ion GO:0032025 1 0.451
positive regulation of phosphorylation GO:0042327 394 0.448
negative regulation of i kappab kinase nf kappab signaling GO:0043124 32 0.446
muscle cell fate commitment GO:0042693 4 0.445
regulation of execution phase of apoptosis GO:1900117 11 0.445
protein deubiquitination GO:0016579 79 0.444
positive regulation of protein polyubiquitination GO:1902916 3 0.438
response to nitrogen compound GO:1901698 184 0.437
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.433
negative regulation of phosphorylation GO:0042326 174 0.433
regulation of cell differentiation GO:0045595 393 0.427
epithelium development GO:0060429 227 0.424
negative regulation of endothelial cell chemotaxis GO:2001027 4 0.417
ubiquitin dependent smad protein catabolic process GO:0030579 4 0.414
system process GO:0003008 349 0.412
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.411
myeloid cell homeostasis GO:0002262 34 0.410
cellular response to misfolded protein GO:0071218 2 0.402
canonical wnt signaling pathway GO:0060070 116 0.401
negative regulation of hydrolase activity GO:0051346 182 0.400
neuron fate commitment GO:0048663 2 0.400
substantia nigra development GO:0021762 45 0.394
head development GO:0060322 108 0.394
regulation of secretion GO:0051046 194 0.393
signal transduction involved in dna integrity checkpoint GO:0072401 15 0.391
positive regulation of defense response GO:0031349 87 0.391
regulation of lymphocyte apoptotic process GO:0070228 15 0.388
Human
cellular response to radiation GO:0071478 65 0.385
mitotic cell cycle process GO:1903047 286 0.372
histone ubiquitination GO:0016574 31 0.372
response to mechanical stimulus GO:0009612 51 0.372
hematopoietic or lymphoid organ development GO:0048534 186 0.370
response to steroid hormone GO:0048545 80 0.369
spermatid development GO:0007286 4 0.367
regulation of protein processing GO:0070613 150 0.362
limbic system development GO:0021761 3 0.361
cellular response to glucocorticoid stimulus GO:0071385 4 0.360
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.353
protein k63 linked ubiquitination GO:0070534 31 0.352
Human
neuron death GO:0070997 65 0.349
Mouse Rat
regulation of cytokine production GO:0001817 232 0.348
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.348
regulation of protein serine threonine kinase activity GO:0071900 179 0.343
renal system development GO:0072001 63 0.340
g1 s transition of mitotic cell cycle GO:0000082 78 0.340
leukocyte differentiation GO:0002521 98 0.337
mitral valve development GO:0003174 3 0.334
neuron apoptotic process GO:0051402 39 0.330
Mouse Rat
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.327
activation of innate immune response GO:0002218 55 0.326
natural killer cell apoptotic process GO:0070246 1 0.325
Human
regulation of map kinase activity GO:0043405 108 0.319
apoptotic nuclear changes GO:0030262 13 0.318
cell death in response to oxidative stress GO:0036473 29 0.317
negative regulation of cell proliferation GO:0008285 228 0.309
regulation of secretion by cell GO:1903530 177 0.304
positive regulation of organelle organization GO:0010638 195 0.298
ventricular septum morphogenesis GO:0060412 3 0.298
response to light stimulus GO:0009416 87 0.294
segmentation GO:0035282 4 0.294
regulation of dna metabolic process GO:0051052 153 0.293
mitochondrion organization GO:0007005 156 0.289
negative regulation of cell cycle GO:0045786 193 0.289
cell fate commitment involved in pattern specification GO:0060581 1 0.287
positive regulation of protein phosphorylation GO:0001934 313 0.286
response to xenobiotic stimulus GO:0009410 30 0.286
negative regulation of cellular protein metabolic process GO:0032269 353 0.277
cellular component disassembly involved in execution phase of apoptosis GO:0006921 13 0.276
response to metal ion GO:0010038 84 0.274
immune response activating signal transduction GO:0002757 90 0.269
cellular response to toxic substance GO:0097237 4 0.269
response to inorganic substance GO:0010035 127 0.264
primary neural tube formation GO:0014020 3 0.263
negative regulation of developmental process GO:0051093 247 0.257
humoral immune response GO:0006959 49 0.252
response to alkaloid GO:0043279 20 0.250
ventricular trabecula myocardium morphogenesis GO:0003222 1 0.249
central nervous system development GO:0007417 123 0.249
vascular smooth muscle cell development GO:0097084 1 0.248
regulation of mapk cascade GO:0043408 262 0.244
positive regulation of mesonephros development GO:0061213 2 0.244
negative regulation of kinase activity GO:0033673 106 0.243
cellular response to xenobiotic stimulus GO:0071466 29 0.243
regulation of protein kinase activity GO:0045859 289 0.242
secondary metabolic process GO:0019748 17 0.241
protein oligomerization GO:0051259 173 0.241
mitral valve morphogenesis GO:0003183 2 0.237
positive regulation of wnt signaling pathway GO:0030177 54 0.237
atrial septum morphogenesis GO:0060413 5 0.235
brain development GO:0007420 97 0.235
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 13 0.234
aortic valve morphogenesis GO:0003180 3 0.231
negative regulation of gliogenesis GO:0014014 3 0.230
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.229
neuroblast proliferation GO:0007405 4 0.223
regulation of protein localization GO:0032880 296 0.222
negative regulation of intracellular signal transduction GO:1902532 183 0.221
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.218
glial cell apoptotic process GO:0034349 7 0.210
neuron differentiation GO:0030182 138 0.206
regulation of endodermal cell fate specification GO:0042663 1 0.203
dna catabolic process GO:0006308 49 0.198
positive regulation of nucleotide metabolic process GO:0045981 230 0.194
i kappab phosphorylation GO:0007252 7 0.193
anatomical structure formation involved in morphogenesis GO:0048646 284 0.192
response to alcohol GO:0097305 64 0.192
cellular response to antibiotic GO:0071236 1 0.192
carboxylic acid catabolic process GO:0046395 71 0.190
tissue morphogenesis GO:0048729 96 0.186
regulation of protein stability GO:0031647 87 0.186
response to antibiotic GO:0046677 15 0.182
cellular response to corticosteroid stimulus GO:0071384 5 0.181
response to oxygen levels GO:0070482 100 0.179
positive regulation of hydrolase activity GO:0051345 331 0.178
somitogenesis GO:0001756 2 0.177
cellular response to hormone stimulus GO:0032870 125 0.173
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.171
trabecula morphogenesis GO:0061383 2 0.170
regulation of leukocyte activation GO:0002694 115 0.167
erythrocyte homeostasis GO:0034101 31 0.164
cellular response to organic cyclic compound GO:0071407 127 0.163
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.162
response to retinoic acid GO:0032526 33 0.161
hippocampus development GO:0021766 1 0.159
alpha amino acid catabolic process GO:1901606 26 0.154
reproduction GO:0000003 63 0.151
response to estrogen GO:0043627 47 0.150
dna repair GO:0006281 198 0.150
hair cell differentiation GO:0035315 2 0.150
negative regulation of glial cell proliferation GO:0060253 2 0.150
cardiac muscle cell myoblast differentiation GO:0060379 5 0.149
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.149
positive regulation of leukocyte differentiation GO:1902107 37 0.149
nervous system development GO:0007399 293 0.146
determination of adult lifespan GO:0008340 2 0.144
regulation of b cell activation GO:0050864 24 0.140
activation of immune response GO:0002253 114 0.140
immunoglobulin secretion GO:0048305 1 0.138
macrophage differentiation GO:0030225 11 0.138
regulation of interleukin 2 secretion GO:1900040 2 0.138
cellular response to dexamethasone stimulus GO:0071549 1 0.138
epithelial cell proliferation GO:0050673 128 0.138
organ morphogenesis GO:0009887 147 0.137
cytokine secretion GO:0050663 64 0.135
protein modification by small protein removal GO:0070646 92 0.133
viral release from host cell GO:0019076 21 0.133
neural tube development GO:0021915 9 0.132
regulation of viral transcription GO:0046782 34 0.130
regulation of t cell proliferation GO:0042129 42 0.128
hair follicle morphogenesis GO:0031069 2 0.128
ribonucleoside triphosphate catabolic process GO:0009203 391 0.127
regulation of endothelial cell differentiation GO:0045601 4 0.125
regulation of gastrulation GO:0010470 12 0.124
vasculature development GO:0001944 181 0.123
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.122
renal system process GO:0003014 25 0.121
cardiac epithelial to mesenchymal transition GO:0060317 3 0.120
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.120
regulation of microtubule cytoskeleton organization GO:0070507 61 0.120
photoreceptor cell differentiation GO:0046530 2 0.119
negative regulation of cell activation GO:0050866 33 0.119
regulation of protein transport GO:0051223 213 0.118
long term memory GO:0007616 2 0.118
endocardial cell differentiation GO:0060956 2 0.118
lipid homeostasis GO:0055088 39 0.115
positive regulation of notch signaling pathway GO:0045747 6 0.115
positive regulation of cardiac muscle cell proliferation GO:0060045 2 0.114
regulation of neuron death GO:1901214 56 0.114
Rat
necroptotic process GO:0070266 16 0.114
Human
activation of mapk activity GO:0000187 45 0.113
response to organic cyclic compound GO:0014070 204 0.113
cellular response to oxidative stress GO:0034599 85 0.112
tube closure GO:0060606 3 0.111
homeostasis of number of cells GO:0048872 40 0.111
positive regulation of gtp catabolic process GO:0033126 166 0.111
interaction with host GO:0051701 42 0.110
actin filament based process GO:0030029 224 0.110
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 4 0.109
cardiac endothelial cell differentiation GO:0003348 2 0.109
negative regulation of protein modification process GO:0031400 200 0.108
ventral spinal cord interneuron differentiation GO:0021514 1 0.108
post embryonic development GO:0009791 2 0.108
positive regulation of catabolic process GO:0009896 310 0.107
regulation of proteasomal protein catabolic process GO:0061136 87 0.106
atrioventricular valve morphogenesis GO:0003181 2 0.106
heart formation GO:0060914 2 0.105
cytokine production GO:0001816 247 0.105
neurological system process GO:0050877 163 0.105
nucleoside triphosphate metabolic process GO:0009141 422 0.105
organelle fission GO:0048285 149 0.105
b cell homeostasis GO:0001782 1 0.104
response to ketone GO:1901654 19 0.103
actin cytoskeleton organization GO:0030036 207 0.103
blood vessel development GO:0001568 172 0.102
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.102
response to decreased oxygen levels GO:0036293 96 0.102
positive regulation of gtpase activity GO:0043547 166 0.101
notch signaling pathway GO:0007219 31 0.100
positive regulation of immune response GO:0050778 159 0.099
endocardium development GO:0003157 2 0.099
cardiac atrium morphogenesis GO:0003209 7 0.099
positive regulation of cellular catabolic process GO:0031331 284 0.097
skin development GO:0043588 76 0.096
sprouting angiogenesis GO:0002040 29 0.096
embryonic hindlimb morphogenesis GO:0035116 2 0.096
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.096
organophosphate catabolic process GO:0046434 430 0.096
motor neuron axon guidance GO:0008045 2 0.096
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.095
cellular response to growth factor stimulus GO:0071363 197 0.094
positive regulation of innate immune response GO:0045089 79 0.093
immune response GO:0006955 307 0.092
leukocyte apoptotic process GO:0071887 31 0.091
Human
t cell proliferation GO:0042098 45 0.089
protein stabilization GO:0050821 64 0.089
morphogenesis of a branching structure GO:0001763 21 0.088
spermatogenesis GO:0007283 22 0.088
positive regulation of stress activated mapk cascade GO:0032874 60 0.087
glomerular mesangial cell differentiation GO:0072008 2 0.087
positive regulation of protein kinase activity GO:0045860 190 0.087
negative regulation of myotube differentiation GO:0010832 4 0.087
negative regulation of secretion by cell GO:1903531 52 0.087
negative regulation of pro b cell differentiation GO:2000974 1 0.086
atrioventricular valve development GO:0003171 3 0.086
positive regulation of cellular component organization GO:0051130 376 0.086
regulation of viral release from host cell GO:1902186 20 0.086
organelle assembly GO:0070925 176 0.085
multi organism cellular process GO:0044764 156 0.085
cellular response to gonadotropin stimulus GO:0071371 4 0.084
response to organonitrogen compound GO:0010243 156 0.084
negative regulation of transferase activity GO:0051348 124 0.082
purine ribonucleoside metabolic process GO:0046128 437 0.081
hindlimb morphogenesis GO:0035137 2 0.081
protein homooligomerization GO:0051260 100 0.081
regulation of cardioblast differentiation GO:0051890 4 0.080
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.080
negative regulation of multi organism process GO:0043901 92 0.079
viral gene expression GO:0019080 35 0.079
response to nutrient levels GO:0031667 81 0.077
sensory perception of sound GO:0007605 37 0.077
regulation of protein ubiquitination GO:0031396 95 0.076
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.076
secretion GO:0046903 254 0.076
sulfur compound metabolic process GO:0006790 101 0.075
response to ionizing radiation GO:0010212 65 0.075
digestive tract development GO:0048565 75 0.075
regulation of cellular protein catabolic process GO:1903362 96 0.075
regulation of neuron differentiation GO:0045664 70 0.074
response to corticosteroid GO:0031960 15 0.074
endodermal cell fate specification GO:0001714 4 0.074
response to topologically incorrect protein GO:0035966 29 0.074
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.073
sensory organ development GO:0007423 52 0.073
response to glucocorticoid GO:0051384 13 0.073
positive regulation of protein linear polyubiquitination GO:1902530 2 0.072
venous blood vessel development GO:0060841 2 0.072
chordate embryonic development GO:0043009 34 0.071
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.071
regulation of apoptotic dna fragmentation GO:1902510 3 0.071
positive regulation of nucleotide catabolic process GO:0030813 185 0.070
response to wounding GO:0009611 168 0.069
viral process GO:0016032 146 0.069
defense response to virus GO:0051607 71 0.069
nuclear transport GO:0051169 179 0.068
regulation of protein catabolic process GO:0042176 155 0.068
regulation of defense response to virus GO:0050688 33 0.068
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 2 0.068
reproductive process GO:0022414 106 0.067
guanosine containing compound catabolic process GO:1901069 239 0.067
cardioblast cell fate commitment GO:0042684 1 0.067
multicellular organismal aging GO:0010259 3 0.067
regulation of nucleotide metabolic process GO:0006140 269 0.066
androgen receptor signaling pathway GO:0030521 34 0.065
blood vessel morphogenesis GO:0048514 162 0.065
morphogenesis of embryonic epithelium GO:0016331 4 0.065
kidney development GO:0001822 53 0.064
myoblast proliferation GO:0051450 1 0.064
protein localization to organelle GO:0033365 280 0.064
positive regulation of map kinase activity GO:0043406 80 0.063
positive regulation of mapk cascade GO:0043410 190 0.062
cardiac cell fate specification GO:0060912 1 0.062
response to oxidative stress GO:0006979 121 0.062
regulation of innate immune response GO:0045088 97 0.061
positive regulation of mitotic cell cycle GO:0045931 60 0.061
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.061
regulation of lymphocyte proliferation GO:0050670 64 0.061
negative regulation of viral entry into host cell GO:0046597 12 0.061
branching morphogenesis of an epithelial tube GO:0048754 19 0.061
negative regulation of response to external stimulus GO:0032102 83 0.060
regulation of cell migration involved in sprouting angiogenesis GO:0090049 9 0.060
cellular response to acid chemical GO:0071229 44 0.060

XIAP disease predictions

Disease DO term ID Size Probability Func Analog Org