Homo sapiens

106 known processes

AKR1C2

aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)

(Aliases: AKR1C-pseudo,FLJ53800,DDH2,DD2,DD,HBAB,BABP,MCDR2,HAKRD)

AKR1C2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of retinoic acid biosynthetic process GO:1900053 1 1.000
Human
testosterone biosynthetic process GO:0061370 2 1.000
Human
androgen biosynthetic process GO:0006702 3 1.000
Human
retinoic acid biosynthetic process GO:0002138 2 1.000
Human
regulation of testosterone biosynthetic process GO:2000224 2 1.000
Human
primary alcohol metabolic process GO:0034308 17 1.000
Human
diterpenoid biosynthetic process GO:0016102 2 1.000
Human
cellular response to jasmonic acid stimulus GO:0071395 4 1.000
cellular response to prostaglandin stimulus GO:0071379 4 1.000
Human
sesquiterpenoid catabolic process GO:0016107 2 1.000
Human
terpenoid catabolic process GO:0016115 5 1.000
Human
sterol catabolic process GO:0016127 3 1.000
Human
regulation of isoprenoid metabolic process GO:0019747 1 1.000
Human
terpenoid biosynthetic process GO:0016114 2 1.000
Human
sesquiterpenoid metabolic process GO:0006714 3 1.000
Human
farnesol catabolic process GO:0016488 2 1.000
Human
retinoid metabolic process GO:0001523 18 1.000
Human
isoprenoid catabolic process GO:0008300 7 1.000
Human
cholesterol catabolic process GO:0006707 3 1.000
Human
bile acid metabolic process GO:0008206 14 1.000
Human
regulation of ketone biosynthetic process GO:0010566 7 1.000
Human
response to jasmonic acid GO:0009753 4 0.999
regulation of retinoic acid biosynthetic process GO:1900052 1 0.999
Human
hormone catabolic process GO:0042447 4 0.998
Mouse
cellular hormone metabolic process GO:0034754 41 0.998
diterpenoid metabolic process GO:0016101 20 0.997
Human
ketone biosynthetic process GO:0042181 17 0.997
Human
retinal metabolic process GO:0042574 8 0.997
Human
farnesol metabolic process GO:0016487 2 0.997
Human
terpenoid metabolic process GO:0006721 27 0.997
Human
androgen metabolic process GO:0008209 9 0.997
Human
negative regulation of isoprenoid metabolic process GO:0045827 1 0.996
Human
limbic system development GO:0021761 3 0.996
Rat
aminoglycoside antibiotic metabolic process GO:0030647 8 0.996
prostanoid metabolic process GO:0006692 17 0.996
glycoside metabolic process GO:0016137 13 0.994
retinoic acid metabolic process GO:0042573 7 0.993
Human
cellular response to calcium ion GO:0071277 19 0.992
Human
primary alcohol catabolic process GO:0034310 3 0.990
Human
regulation of vitamin metabolic process GO:0030656 9 0.990
Human
quinone metabolic process GO:1901661 18 0.990
g protein coupled receptor signaling pathway GO:0007186 207 0.987
polyketide metabolic process GO:0030638 8 0.985
regulation of hormone biosynthetic process GO:0046885 10 0.983
Human
lipid catabolic process GO:0016042 84 0.978
Human Mouse
bile acid biosynthetic process GO:0006699 10 0.975
Human
cellular lipid catabolic process GO:0044242 65 0.974
Human
negative regulation of lipid metabolic process GO:0045833 38 0.974
Human
parturition GO:0007567 1 0.971
Mouse
isoprenoid biosynthetic process GO:0008299 9 0.958
Human
hormone metabolic process GO:0042445 61 0.957
unsaturated fatty acid metabolic process GO:0033559 37 0.956
alcohol metabolic process GO:0006066 114 0.955
Human
hippocampus development GO:0021766 1 0.954
Rat
small molecule catabolic process GO:0044282 92 0.953
Human Mouse
carboxylic acid biosynthetic process GO:0046394 97 0.951
Human
isoprenoid metabolic process GO:0006720 39 0.950
Human
organic acid biosynthetic process GO:0016053 97 0.949
Human
daunorubicin metabolic process GO:0044597 8 0.947
cofactor metabolic process GO:0051186 87 0.941
multicellular organismal metabolic process GO:0044236 34 0.940
Human
fatty acid metabolic process GO:0006631 115 0.934
doxorubicin metabolic process GO:0044598 8 0.929
hormone biosynthetic process GO:0042446 22 0.928
Human
steroid metabolic process GO:0008202 94 0.923
negative regulation of hormone metabolic process GO:0032351 6 0.921
Human
monocarboxylic acid biosynthetic process GO:0072330 67 0.919
Human
oxidation reduction process GO:0055114 396 0.914
regulation of reactive oxygen species metabolic process GO:2000377 41 0.913
Human
regulation of hormone metabolic process GO:0032350 14 0.911
Human
organic hydroxy compound catabolic process GO:1901616 22 0.909
Human
regulation of endothelial cell apoptotic process GO:2000351 24 0.906
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.903
Human
keratinocyte differentiation GO:0030216 36 0.897
Human
vitamin metabolic process GO:0006766 26 0.892
Human
small molecule biosynthetic process GO:0044283 157 0.875
Human
lipid biosynthetic process GO:0008610 177 0.874
Human Mouse
prostaglandin metabolic process GO:0006693 17 0.870
response to calcium ion GO:0051592 46 0.868
Human
cellular ketone metabolic process GO:0042180 80 0.865
icosanoid metabolic process GO:0006690 35 0.858
epidermal cell differentiation GO:0009913 45 0.837
Human
cholesterol metabolic process GO:0008203 28 0.836
Human
response to fatty acid GO:0070542 13 0.833
steroid catabolic process GO:0006706 10 0.832
Human Mouse
cellular response to oxidative stress GO:0034599 85 0.829
Human
sterol metabolic process GO:0016125 28 0.820
Human
regulation of alcohol biosynthetic process GO:1902930 22 0.817
Human
negative regulation of vitamin metabolic process GO:0046137 6 0.817
Human
regulation of lipid biosynthetic process GO:0046890 47 0.813
Human
fatty acid derivative metabolic process GO:1901568 35 0.807
secondary metabolic process GO:0019748 17 0.806
cellular lipid metabolic process GO:0044255 303 0.799
organic hydroxy compound biosynthetic process GO:1901617 71 0.798
Human
endothelial cell apoptotic process GO:0072577 26 0.794
Human
retinoic acid receptor signaling pathway GO:0048384 13 0.785
Human
c21 steroid hormone metabolic process GO:0008207 17 0.783
cellular aldehyde metabolic process GO:0006081 20 0.780
Human
male gonad development GO:0008584 23 0.760
Human
organic hydroxy compound metabolic process GO:1901615 147 0.760
Human
lipid metabolic process GO:0006629 381 0.752
regulation of lipid metabolic process GO:0019216 96 0.740
Human
regulation of retinoic acid receptor signaling pathway GO:0048385 9 0.732
Human
positive regulation of endothelial cell apoptotic process GO:2000353 8 0.731
Human
intracellular receptor signaling pathway GO:0030522 104 0.723
Human
cellular response to metal ion GO:0071248 43 0.719
Human
regulation of hormone levels GO:0010817 125 0.710
regulation of steroid metabolic process GO:0019218 32 0.705
Human
steroid biosynthetic process GO:0006694 46 0.702
Human Mouse
cellular response to starvation GO:0009267 58 0.698
Human
response to organophosphorus GO:0046683 41 0.694
Human
regulation of steroid biosynthetic process GO:0050810 23 0.690
Human
cellular response to reactive oxygen species GO:0034614 50 0.671
Human
reactive oxygen species metabolic process GO:0072593 75 0.669
Human
protein oligomerization GO:0051259 173 0.668
Human
cellular response to organic cyclic compound GO:0071407 127 0.666
Human
negative regulation of lipid biosynthetic process GO:0051055 22 0.657
Human
protein homooligomerization GO:0051260 100 0.656
Human
multicellular organismal macromolecule metabolic process GO:0044259 29 0.656
Human
alcohol biosynthetic process GO:0046165 52 0.653
Human
progesterone metabolic process GO:0042448 6 0.651
skin development GO:0043588 76 0.637
Human
male sex differentiation GO:0046661 25 0.622
Human
digestion GO:0007586 22 0.615
cytoplasmic transport GO:0016482 379 0.607
Human
epithelial cell differentiation GO:0030855 141 0.605
positive regulation of cell proliferation GO:0008284 301 0.605
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.603
Human
response to oxidative stress GO:0006979 121 0.601
Human
telencephalon development GO:0021537 17 0.591
Rat
epidermis development GO:0008544 59 0.562
Human
response to cadmium ion GO:0046686 10 0.551
Human
response to estrogen GO:0043627 47 0.544
Rat
positive regulation of cell death GO:0010942 263 0.542
Human
protein localization to organelle GO:0033365 280 0.533
Human
alcohol catabolic process GO:0046164 20 0.532
Human
cellular response to fatty acid GO:0071398 8 0.532
Human
cellular response to inorganic substance GO:0071241 45 0.531
Human
response to reactive oxygen species GO:0000302 61 0.523
Human
response to lipid GO:0033993 206 0.520
cellular response to oxygen containing compound GO:1901701 276 0.514
positive regulation of programmed cell death GO:0043068 249 0.513
Human
positive regulation of apoptotic process GO:0043065 246 0.501
Human
cellular response to external stimulus GO:0071496 111 0.501
Human
response to nutrient GO:0007584 20 0.495
Human
nuclear transport GO:0051169 179 0.493
Human
protein localization to nucleus GO:0034504 136 0.485
Human
cellular response to endogenous stimulus GO:0071495 336 0.481
cellular response to corticosteroid stimulus GO:0071384 5 0.478
Human
response to organic cyclic compound GO:0014070 204 0.458
Human Rat
protein targeting GO:0006605 187 0.444
Human
protein import GO:0017038 130 0.431
Human
nuclear import GO:0051170 106 0.423
Human
protein import into nucleus GO:0006606 104 0.423
Human
protein kinase b signaling GO:0043491 69 0.397
response to drug GO:0042493 81 0.395
Rat
response to hormone GO:0009725 175 0.395
nucleocytoplasmic transport GO:0006913 176 0.380
Human
response to steroid hormone GO:0048545 80 0.379
Human Rat
response to oxygen containing compound GO:1901700 369 0.360
response to starvation GO:0042594 59 0.359
Human
response to acid chemical GO:0001101 66 0.347
response to corticosteroid GO:0031960 15 0.345
Human
cellular response to lipid GO:0071396 127 0.342
Human
regulation of protein kinase b signaling GO:0051896 61 0.340
response to inorganic substance GO:0010035 127 0.338
Human
single organism cellular localization GO:1902580 332 0.337
Human
response to prostaglandin GO:0034694 8 0.323
single organism nuclear import GO:1902593 104 0.297
Human
response to metal ion GO:0010038 84 0.297
Human
protein targeting to nucleus GO:0044744 104 0.292
Human
response to extracellular stimulus GO:0009991 85 0.284
Human
forebrain development GO:0030900 26 0.278
Rat
epithelium development GO:0060429 227 0.265
cellular response to nutrient levels GO:0031669 69 0.259
Human
cell type specific apoptotic process GO:0097285 125 0.255
Human
establishment of protein localization to organelle GO:0072594 172 0.250
Human
nervous system development GO:0007399 293 0.231
Rat
cellular response to acid chemical GO:0071229 44 0.224
cellular response to steroid hormone stimulus GO:0071383 37 0.223
Human
brain development GO:0007420 97 0.205
Rat
protein import into nucleus translocation GO:0000060 22 0.203
Human
response to nutrient levels GO:0031667 81 0.202
Human
cellular response to hormone stimulus GO:0032870 125 0.197
cellular response to cadmium ion GO:0071276 8 0.173
Human
development of primary male sexual characteristics GO:0046546 23 0.155
Human
central nervous system development GO:0007417 123 0.137
Rat
monocarboxylic acid metabolic process GO:0032787 185 0.136
cellular amino acid metabolic process GO:0006520 116 0.116
cellular response to extracellular stimulus GO:0031668 72 0.104
Human
head development GO:0060322 108 0.096
Rat
amine metabolic process GO:0009308 44 0.092
single organism reproductive process GO:0044702 98 0.066
Human
reproductive structure development GO:0048608 55 0.060
Human
regulation of cellular amine metabolic process GO:0033238 11 0.055
regulation of cellular amino acid metabolic process GO:0006521 6 0.054
positive regulation of cellular amine metabolic process GO:0033240 7 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
post embryonic development GO:0009791 2 0.046
gonad development GO:0008406 34 0.044
Human
determination of adult lifespan GO:0008340 2 0.039
cell adhesion GO:0007155 325 0.039
system process GO:0003008 349 0.039
ras protein signal transduction GO:0007265 73 0.038
negative regulation of protein metabolic process GO:0051248 391 0.037
multicellular organismal aging GO:0010259 3 0.035
reproductive system development GO:0061458 56 0.035
Human
regulation of cell migration GO:0030334 289 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
small gtpase mediated signal transduction GO:0007264 78 0.033
development of primary sexual characteristics GO:0045137 35 0.033
Human
organophosphate catabolic process GO:0046434 430 0.033
transmembrane transport GO:0055085 399 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.031
positive regulation of hydrolase activity GO:0051345 331 0.031
response to abiotic stimulus GO:0009628 336 0.031
cellular amine metabolic process GO:0044106 41 0.031
organonitrogen compound biosynthetic process GO:1901566 200 0.030
reproductive process GO:0022414 106 0.030
Human Mouse
regulation of cellular component movement GO:0051270 334 0.030
chemical homeostasis GO:0048878 306 0.030
purine containing compound catabolic process GO:0072523 411 0.030
purine nucleotide catabolic process GO:0006195 405 0.030
positive regulation of catabolic process GO:0009896 310 0.030
response to external biotic stimulus GO:0043207 261 0.029
apoptotic signaling pathway GO:0097190 268 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
nucleoside triphosphate catabolic process GO:0009143 394 0.028
nucleoside catabolic process GO:0009164 408 0.028
cytokine production GO:0001816 247 0.028
regulation of kinase activity GO:0043549 314 0.028
negative regulation of cell death GO:0060548 345 0.027
positive regulation of transport GO:0051050 336 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
signal transduction by phosphorylation GO:0023014 297 0.026
biological adhesion GO:0022610 331 0.026
negative regulation of programmed cell death GO:0043069 321 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
female gamete generation GO:0007292 2 0.026
innate immune response GO:0045087 178 0.026
segmentation GO:0035282 4 0.025
inorganic ion transmembrane transport GO:0098660 231 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
oogenesis GO:0048477 2 0.025
purine nucleoside triphosphate metabolic process GO:0009144 412 0.025
purine nucleoside catabolic process GO:0006152 398 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
intracellular protein transport GO:0006886 270 0.025
Human
vesicle mediated transport GO:0016192 371 0.025
ion homeostasis GO:0050801 230 0.024
sex differentiation GO:0007548 45 0.024
Human
cardiovascular system development GO:0072358 262 0.024
carbohydrate metabolic process GO:0005975 207 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
ribonucleotide catabolic process GO:0009261 405 0.024
mapk cascade GO:0000165 288 0.024
single organism membrane organization GO:0044802 268 0.024
negative regulation of apoptotic process GO:0043066 316 0.024
regulation of secretion by cell GO:1903530 177 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.023
locomotory behavior GO:0007626 1 0.023
single organism carbohydrate metabolic process GO:0044723 193 0.023
nucleoside phosphate catabolic process GO:1901292 412 0.023
ribonucleoside triphosphate metabolic process GO:0009199 412 0.023
regulation of purine nucleotide metabolic process GO:1900542 264 0.023
regulation of cellular component biogenesis GO:0044087 281 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
regulation of cytokine production GO:0001817 232 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
multi organism reproductive process GO:0044703 54 0.022
Mouse
regulation of protein kinase activity GO:0045859 289 0.022
negative regulation of developmental process GO:0051093 247 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
reactive oxygen species biosynthetic process GO:1903409 4 0.022
regulation of apoptotic signaling pathway GO:2001233 175 0.022
positive regulation of protein phosphorylation GO:0001934 313 0.022
cellular homeostasis GO:0019725 196 0.022
actin filament based process GO:0030029 224 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.022
purine ribonucleotide catabolic process GO:0009154 404 0.022
regulation of protein transport GO:0051223 213 0.022
positive regulation of nucleotide metabolic process GO:0045981 230 0.021
gtp metabolic process GO:0046039 239 0.021
cell morphogenesis GO:0000902 296 0.021
nitrogen compound transport GO:0071705 191 0.021
cellular macromolecule catabolic process GO:0044265 380 0.021
positive regulation of developmental process GO:0051094 314 0.021
rho protein signal transduction GO:0007266 26 0.021
nucleoside triphosphate metabolic process GO:0009141 422 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
adult locomotory behavior GO:0008344 1 0.021
memory GO:0007613 3 0.021
immune response GO:0006955 307 0.020
cell development GO:0048468 328 0.020
peripheral nervous system development GO:0007422 2 0.020
regeneration GO:0031099 4 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.020
regulation of transferase activity GO:0051338 355 0.020
response to nitrogen compound GO:1901698 184 0.020
regulation of purine nucleotide catabolic process GO:0033121 205 0.020
positive regulation of phosphorylation GO:0042327 394 0.020
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.020
single organism cell adhesion GO:0098602 179 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.019
neuromuscular junction development GO:0007528 3 0.019
regulation of protein localization GO:0032880 296 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
spermatid differentiation GO:0048515 4 0.019
positive regulation of cell differentiation GO:0045597 211 0.019
protein catabolic process GO:0030163 325 0.019
maintenance of location GO:0051235 112 0.019
cellular protein catabolic process GO:0044257 261 0.018
ion transmembrane transport GO:0034220 338 0.018
secretion by cell GO:0032940 226 0.018
mitotic cell cycle GO:0000278 326 0.018
defense response GO:0006952 315 0.018
cellular response to cytokine stimulus GO:0071345 181 0.018
anterior posterior axis specification GO:0009948 2 0.018
regulation of cell cycle GO:0051726 393 0.018
regulation of nucleotide catabolic process GO:0030811 205 0.018
response to organonitrogen compound GO:0010243 156 0.018
morphogenesis of embryonic epithelium GO:0016331 4 0.018
dephosphorylation GO:0016311 209 0.018
positive regulation of nucleotide catabolic process GO:0030813 185 0.018
response to cytokine GO:0034097 232 0.018
positive regulation of synaptic transmission GO:0050806 4 0.018
regulation of cell cycle process GO:0010564 266 0.018
metal ion transport GO:0030001 272 0.018
regulation of proteolysis GO:0030162 293 0.018
positive regulation of transferase activity GO:0051347 227 0.018
gtp catabolic process GO:0006184 237 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
nucleotide catabolic process GO:0009166 408 0.018
guanosine containing compound catabolic process GO:1901069 239 0.017
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
cation transmembrane transport GO:0098655 238 0.017
positive regulation of organelle organization GO:0010638 195 0.017
response to fungus GO:0009620 4 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
hindbrain development GO:0030902 3 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
regulation of ras protein signal transduction GO:0046578 155 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
protein maturation GO:0051604 233 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
positive regulation of immune system process GO:0002684 283 0.017
metal ion homeostasis GO:0055065 169 0.017
morphogenesis of a polarized epithelium GO:0001738 3 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
reactive nitrogen species metabolic process GO:2001057 3 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
regulation of cell adhesion GO:0030155 166 0.017
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.017
regulation of mapk cascade GO:0043408 262 0.017
tissue migration GO:0090130 119 0.016
negative regulation of protein modification process GO:0031400 200 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
negative regulation of transport GO:0051051 176 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.016
regulation of synaptic plasticity GO:0048167 3 0.016
regulation of peptidase activity GO:0052547 180 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of cell differentiation GO:0045595 393 0.016
cardiac muscle cell contraction GO:0086003 4 0.016
regulation of intracellular transport GO:0032386 195 0.016
regulation of response to wounding GO:1903034 101 0.016
negative regulation of protein processing GO:0010955 142 0.016
oocyte development GO:0048599 1 0.016
regulation of protein processing GO:0070613 150 0.016
oocyte differentiation GO:0009994 2 0.016
ameboidal type cell migration GO:0001667 135 0.016
regulation of cellular response to stress GO:0080135 244 0.016
rhythmic behavior GO:0007622 2 0.016
negative regulation of cell motility GO:2000146 104 0.016
cellular component morphogenesis GO:0032989 314 0.015
regulation of defense response GO:0031347 154 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
epidermis morphogenesis GO:0048730 3 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
spermatid development GO:0007286 4 0.015
inner ear morphogenesis GO:0042472 4 0.015
regulation of secretion GO:0051046 194 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
positive regulation of gtpase activity GO:0043547 166 0.015
cellular ion homeostasis GO:0006873 168 0.015
regulation of growth GO:0040008 165 0.015
cellular response to organonitrogen compound GO:0071417 124 0.015
membrane organization GO:0061024 292 0.015
neurotransmitter secretion GO:0007269 4 0.015
protein ubiquitination GO:0016567 314 0.015
epithelium migration GO:0090132 119 0.015
tripartite regional subdivision GO:0007351 2 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
positive regulation of kinase activity GO:0033674 204 0.015
extrinsic apoptotic signaling pathway GO:0097191 119 0.015
mitotic cell cycle process GO:1903047 286 0.015
cell activation GO:0001775 213 0.015
anterior posterior axis specification embryo GO:0008595 2 0.015
regulation of gtp catabolic process GO:0033124 180 0.015
cell fate determination GO:0001709 3 0.015
response to other organism GO:0051707 261 0.015
glial cell migration GO:0008347 4 0.015
rna processing GO:0006396 255 0.014
Mouse
regulation of cytoplasmic transport GO:1903649 149 0.014
positive regulation of cytokine production GO:0001819 167 0.014
single organismal cell cell adhesion GO:0016337 148 0.014
lipid localization GO:0010876 106 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
tissue regeneration GO:0042246 3 0.014
response to biotic stimulus GO:0009607 276 0.014
nerve development GO:0021675 4 0.014
mitochondrion organization GO:0007005 156 0.014
positive regulation of secretion GO:0051047 116 0.014
cellular response to nitrogen compound GO:1901699 144 0.014
cellular amide metabolic process GO:0043603 69 0.014
cell growth GO:0016049 160 0.014
epithelial cell migration GO:0010631 119 0.014
immune system development GO:0002520 195 0.014
neurological system process GO:0050877 163 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
establishment of protein localization to membrane GO:0090150 121 0.014
negative regulation of cell cycle GO:0045786 193 0.014
startle response GO:0001964 3 0.014
cellular protein complex assembly GO:0043623 188 0.014
circadian behavior GO:0048512 2 0.014
neuroblast proliferation GO:0007405 4 0.014
microtubule based process GO:0007017 210 0.014
negative regulation of protein maturation GO:1903318 142 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
chromatin modification GO:0016568 298 0.014
stem cell division GO:0017145 2 0.014
response to axon injury GO:0048678 1 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
metencephalon development GO:0022037 2 0.014
positive regulation of protein transport GO:0051222 135 0.014
rna interference GO:0016246 4 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
regulation of membrane potential GO:0042391 95 0.014
protein processing GO:0016485 226 0.014
regulation of ion transport GO:0043269 189 0.013
regulation of cell development GO:0060284 161 0.013
compound eye development GO:0048749 1 0.013
response to growth factor GO:0070848 205 0.013
cellular cation homeostasis GO:0030003 163 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
cell projection organization GO:0030030 252 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.013
organ formation GO:0048645 3 0.013
actin mediated cell contraction GO:0070252 12 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
neurogenesis GO:0022008 169 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
myeloid cell differentiation GO:0030099 117 0.013
regulation of gtpase activity GO:0043087 180 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
motor neuron axon guidance GO:0008045 2 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
blastoderm segmentation GO:0007350 2 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
regulation of protein catabolic process GO:0042176 155 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
coenzyme metabolic process GO:0006732 65 0.013
positive regulation of gliogenesis GO:0014015 4 0.013
salivary gland morphogenesis GO:0007435 4 0.013
regulation of vasculature development GO:1901342 97 0.013
cation transport GO:0006812 331 0.013
organophosphate biosynthetic process GO:0090407 163 0.013

AKR1C2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.042
Human
nervous system disease DOID:863 431 0.027
sensory system disease DOID:0050155 203 0.027
musculoskeletal system disease DOID:17 223 0.024
eye and adnexa disease DOID:1492 150 0.023
central nervous system disease DOID:331 186 0.022
disease of cellular proliferation DOID:14566 174 0.019
cancer DOID:162 167 0.019
organ system cancer DOID:0050686 164 0.019
eye disease DOID:5614 149 0.017
immune system disease DOID:2914 155 0.017
inherited metabolic disorder DOID:655 242 0.015
Human
bone disease DOID:0080001 88 0.014
connective tissue disease DOID:65 109 0.014
hematopoietic system disease DOID:74 100 0.014
muscle tissue disease DOID:66 113 0.014
muscular disease DOID:0080000 114 0.014