Homo sapiens

199 known processes

DDX58

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

(Aliases: DKFZp434J1111,FLJ13599,RIG-I,DKFZp686N19181)

DDX58 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
viral life cycle GO:0019058 132 1.000
negative regulation of viral process GO:0048525 66 0.999
modulation of molecular function in other organism GO:0044359 2 0.999
regulation of defense response to virus GO:0050688 33 0.998
multi organism cellular process GO:0044764 156 0.998
positive regulation of rig i signaling pathway GO:1900246 4 0.997
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.997
regulation of viral process GO:0050792 103 0.997
defense response to virus GO:0051607 71 0.997
response to virus GO:0009615 126 0.995
activation of innate immune response GO:0002218 55 0.995
response to other organism GO:0051707 261 0.994
modulation of molecular function in other organism involved in symbiotic interaction GO:0052205 2 0.994
response to biotic stimulus GO:0009607 276 0.993
pattern recognition receptor signaling pathway GO:0002221 48 0.992
regulation of multi organism process GO:0043900 157 0.992
positive regulation of cytokine production GO:0001819 167 0.991
viral process GO:0016032 146 0.990
response to dsrna GO:0043331 25 0.989
Human Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.989
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.989
interspecies interaction between organisms GO:0044419 156 0.989
defense response to other organism GO:0098542 129 0.981
innate immune response activating signal transduction GO:0002758 48 0.976
positive regulation of interferon alpha production GO:0032727 11 0.975
intracellular receptor signaling pathway GO:0030522 104 0.974
positive regulation of innate immune response GO:0045089 79 0.973
defense response GO:0006952 315 0.969
positive regulation of interferon beta production GO:0032728 17 0.968
cytokine production GO:0001816 247 0.962
regulation of cytokine production GO:0001817 232 0.961
positive regulation of type i interferon production GO:0032481 20 0.956
regulation of interferon alpha production GO:0032647 11 0.948
negative regulation of viral genome replication GO:0045071 35 0.947
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.946
Human
viral genome replication GO:0019079 50 0.935
immune response GO:0006955 307 0.934
negative regulation of molecular function in other organism GO:0044362 2 0.932
response to organic cyclic compound GO:0014070 204 0.917
Human Mouse
innate immune response GO:0045087 178 0.914
response to external biotic stimulus GO:0043207 261 0.913
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.907
regulation of type i interferon production GO:0032479 26 0.904
regulation of viral genome replication GO:0045069 48 0.902
immune response regulating signaling pathway GO:0002764 97 0.901
negative regulation of multi organism process GO:0043901 92 0.897
Human
cellular response to dsrna GO:0071359 19 0.895
Human
regulation of response to biotic stimulus GO:0002831 55 0.891
immune effector process GO:0002252 159 0.884
response to cytokine GO:0034097 232 0.879
i kappab kinase nf kappab signaling GO:0007249 166 0.869
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.868
regulation of defense response GO:0031347 154 0.853
interaction with host GO:0051701 42 0.850
type i interferon production GO:0032606 27 0.809
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.796
protein deubiquitination GO:0016579 79 0.795
positive regulation of multi organism process GO:0043902 56 0.755
immune response activating signal transduction GO:0002757 90 0.748
regulation of protein localization to nucleus GO:1900180 85 0.722
positive regulation of defense response GO:0031349 87 0.718
negative regulation of viral release from host cell GO:1902187 12 0.716
negative regulation of defense response to virus GO:0050687 10 0.712
Human
cellular response to organic cyclic compound GO:0071407 127 0.689
Human
regulation of defense response to virus by host GO:0050691 22 0.682
entry into host GO:0044409 25 0.682
protein localization to nucleus GO:0034504 136 0.635
regulation of nucleocytoplasmic transport GO:0046822 98 0.628
protein targeting GO:0006605 187 0.620
regulation of immune response GO:0050776 201 0.592
regulation of viral entry into host cell GO:0046596 17 0.583
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 12 0.576
regulation of protein transport GO:0051223 213 0.565
regulation of rig i signaling pathway GO:0039535 6 0.536
Human
regulation of cytoplasmic transport GO:1903649 149 0.530
regulation of intracellular transport of viral material GO:1901252 2 0.530
regulation of interferon beta production GO:0032648 22 0.526
regulation of viral release from host cell GO:1902186 20 0.525
activation of immune response GO:0002253 114 0.506
nuclear transport GO:0051169 179 0.487
negative regulation of molecular function in other organism involved in symbiotic interaction GO:0052204 2 0.476
positive regulation of immune system process GO:0002684 283 0.470
rig i signaling pathway GO:0039529 7 0.464
protein import into nucleus GO:0006606 104 0.451
negative regulation of immune system process GO:0002683 136 0.450
Human
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 8 0.441
regulation of establishment of protein localization GO:0070201 242 0.440
negative regulation of transport GO:0051051 176 0.432
positive regulation of immune response GO:0050778 159 0.414
regulation of innate immune response GO:0045088 97 0.401
cellular response to nitrogen compound GO:1901699 144 0.401
Human
regulation of response to external stimulus GO:0032101 222 0.393
response to lipid GO:0033993 206 0.391
regulation of intracellular protein transport GO:0033157 123 0.390
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.389
viral release from host cell GO:0019076 21 0.364
negative regulation of locomotion GO:0040013 118 0.332
regulation of intracellular transport GO:0032386 195 0.325
positive regulation of response to external stimulus GO:0032103 88 0.316
single organism cellular localization GO:1902580 332 0.314
movement in host environment GO:0052126 25 0.303
positive regulation of cell death GO:0010942 263 0.289
response to nitrogen compound GO:1901698 184 0.268
Human Mouse
cellular response to virus GO:0098586 9 0.252
modification dependent macromolecule catabolic process GO:0043632 212 0.252
intracellular protein transport GO:0006886 270 0.249
chemical homeostasis GO:0048878 306 0.248
regulation of transcription factor import into nucleus GO:0042990 39 0.231
protein modification by small protein conjugation GO:0032446 342 0.220
Human
response to oxygen containing compound GO:1901700 369 0.219
negative regulation of protein transport GO:0051224 75 0.217
protein ubiquitination GO:0016567 314 0.216
regulation of cytoskeleton organization GO:0051493 177 0.197
negative regulation of protein metabolic process GO:0051248 391 0.194
protein modification by small protein removal GO:0070646 92 0.192
cytoplasmic transport GO:0016482 379 0.169
establishment of protein localization to organelle GO:0072594 172 0.169
nuclear import GO:0051170 106 0.167
positive regulation of apoptotic signaling pathway GO:2001235 70 0.167
interferon alpha production GO:0032607 11 0.163
negative regulation of catalytic activity GO:0043086 335 0.163
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.161
cellular macromolecule catabolic process GO:0044265 380 0.161
rna catabolic process GO:0006401 71 0.159
positive regulation of cellular catabolic process GO:0031331 284 0.152
regulation of protein targeting GO:1903533 91 0.151
protein targeting to nucleus GO:0044744 104 0.150
interferon beta production GO:0032608 23 0.150
positive regulation of mrna catabolic process GO:0061014 10 0.143
mrna metabolic process GO:0016071 175 0.138
wnt signaling pathway GO:0016055 156 0.136
regulation of mrna catabolic process GO:0061013 13 0.133
protein import GO:0017038 130 0.130
fas signaling pathway GO:0036337 3 0.128
regulation of immune effector process GO:0002697 91 0.127
positive regulation of programmed cell death GO:0043068 249 0.126
positive regulation of mapk cascade GO:0043410 190 0.126
regulation of locomotion GO:0040012 329 0.120
multi organism intracellular transport GO:1902583 14 0.117
negative regulation of developmental process GO:0051093 247 0.113
stress activated protein kinase signaling cascade GO:0031098 94 0.108
negative regulation of protein import into nucleus GO:0042308 30 0.108
negative regulation of intracellular signal transduction GO:1902532 183 0.105
Human
negative regulation of protein ubiquitination GO:0031397 35 0.101
protein autoubiquitination GO:0051865 37 0.101
regulation of protein localization GO:0032880 296 0.096
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.095
regulation of mda 5 signaling pathway GO:0039533 4 0.094
Human
negative regulation of intracellular transport GO:0032387 60 0.093
multi organism transport GO:0044766 14 0.091
protein localization to organelle GO:0033365 280 0.091
negative regulation of defense response to virus by host GO:0050689 4 0.088
cellular response to interferon alpha GO:0035457 4 0.087
transport of virus GO:0046794 14 0.087
regulation of protein import into nucleus GO:0042306 78 0.084
viral entry into host cell GO:0046718 24 0.082
positive regulation of catabolic process GO:0009896 310 0.082
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.082
nucleoside phosphate biosynthetic process GO:1901293 109 0.082
cellular response to lipopolysaccharide GO:0071222 57 0.081
regulation of protein deubiquitination GO:0090085 4 0.080
cellular response to molecule of bacterial origin GO:0071219 62 0.080
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.080
negative regulation of protein deubiquitination GO:0090086 3 0.079
positive regulation of immune effector process GO:0002699 40 0.078
mrna catabolic process GO:0006402 56 0.078
regulation of cell cycle GO:0051726 393 0.076
negative regulation of cellular protein metabolic process GO:0032269 353 0.076
response to hormone GO:0009725 175 0.075
cellular response to type i interferon GO:0071357 12 0.075
response to vitamin d GO:0033280 10 0.073
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.073
negative regulation of cytokine production GO:0001818 82 0.071
Human
regulation of protein maturation GO:1903317 150 0.071
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.071
negative regulation of multicellular organismal process GO:0051241 317 0.070
Human
viral transcription GO:0019083 35 0.068
vesicle mediated transport GO:0016192 371 0.068
regulation of angiogenesis GO:0045765 92 0.065
regulation of interleukin 2 secretion GO:1900040 2 0.064
response to bacterium GO:0009617 144 0.064
negative regulation of cytoplasmic transport GO:1903650 46 0.063
negative regulation of cell death GO:0060548 345 0.062
negative regulation of phosphate metabolic process GO:0045936 267 0.061
interleukin 2 secretion GO:0070970 3 0.061
protein k63 linked deubiquitination GO:0070536 21 0.061
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.060
mapk cascade GO:0000165 288 0.060
positive regulation of intracellular transport GO:0032388 104 0.059
regulation of fas signaling pathway GO:1902044 2 0.056
negative regulation of response to external stimulus GO:0032102 83 0.055
Human
protein polyubiquitination GO:0000209 110 0.054
regulation of apoptotic signaling pathway GO:2001233 175 0.053
regulation of dna binding GO:0051101 37 0.053
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.052
regulation of mitotic cell cycle GO:0007346 189 0.052
cellular response to cytokine stimulus GO:0071345 181 0.051
mitotic cell cycle GO:0000278 326 0.050
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.050
regulation of cell differentiation GO:0045595 393 0.050
positive regulation of viral process GO:0048524 37 0.049
rna interference GO:0016246 4 0.049
Human Worm
ion transmembrane transport GO:0034220 338 0.049
positive regulation of hydrolase activity GO:0051345 331 0.049
regulation of anatomical structure morphogenesis GO:0022603 286 0.048
dna repair GO:0006281 198 0.048
mda 5 signaling pathway GO:0039530 4 0.046
Human
actin filament based process GO:0030029 224 0.046
negative regulation of cell proliferation GO:0008285 228 0.046
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.045
negative regulation of protein modification process GO:0031400 200 0.045
negative regulation of cell differentiation GO:0045596 171 0.045
negative regulation of sodium ion transmembrane transporter activity GO:2000650 2 0.045
blood vessel morphogenesis GO:0048514 162 0.044
nucleocytoplasmic transport GO:0006913 176 0.044
endosomal transport GO:0016197 129 0.044
multi organism metabolic process GO:0044033 41 0.043
negative regulation of protein maturation GO:1903318 142 0.043
epithelial cell migration GO:0010631 119 0.042
protein k63 linked ubiquitination GO:0070534 31 0.041
apoptotic signaling pathway GO:0097190 268 0.041
response to steroid hormone GO:0048545 80 0.040
cation transport GO:0006812 331 0.040
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.039
negative regulation of programmed cell death GO:0043069 321 0.038
regulation of epithelial cell migration GO:0010632 93 0.038
regulation of cellular component movement GO:0051270 334 0.038
regulation of binding GO:0051098 111 0.037
cellular protein catabolic process GO:0044257 261 0.037
negative regulation of calcium ion import GO:0090281 1 0.037
positive regulation of protein complex assembly GO:0031334 86 0.036
protein monoubiquitination GO:0006513 39 0.036
response to molecule of bacterial origin GO:0002237 82 0.036
positive regulation of protein transport GO:0051222 135 0.036
positive regulation of phosphorylation GO:0042327 394 0.036
positive regulation of response to biotic stimulus GO:0002833 18 0.036
regulation of ion transport GO:0043269 189 0.035
determination of adult lifespan GO:0008340 2 0.035
glycosylation GO:0070085 71 0.035
negative regulation of immune effector process GO:0002698 38 0.035
Human
positive regulation of proteolysis GO:0045862 142 0.035
calcium ion transport GO:0006816 147 0.034
regulation of proteolysis GO:0030162 293 0.034
lipoprotein biosynthetic process GO:0042158 33 0.034
transmembrane transport GO:0055085 399 0.034
regulation of actin filament based process GO:0032970 141 0.033
ion homeostasis GO:0050801 230 0.033
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.033
response to alcohol GO:0097305 64 0.033
modification dependent protein catabolic process GO:0019941 209 0.033
protein secretion GO:0009306 98 0.032
cellular macromolecular complex assembly GO:0034622 324 0.032
Human
negative regulation of cell motility GO:2000146 104 0.032
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.031
Human
protein maturation GO:0051604 233 0.031
ribonucleoprotein complex assembly GO:0022618 78 0.031
Human
cellular response to dna damage stimulus GO:0006974 379 0.031
multicellular organismal aging GO:0010259 3 0.031
chromatin organization GO:0006325 351 0.031
carbohydrate derivative biosynthetic process GO:1901137 207 0.031
viral gene expression GO:0019080 35 0.030
regulation of cell motility GO:2000145 299 0.030
negative regulation of intracellular protein transport GO:0090317 42 0.030
regulation of cell migration GO:0030334 289 0.030
ameboidal type cell migration GO:0001667 135 0.029
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 38 0.029
negative regulation of proteolysis GO:0045861 132 0.029
response to nutrient levels GO:0031667 81 0.029
regulation of t cell activation GO:0050863 77 0.028
regulation of endothelial cell migration GO:0010594 67 0.028
intracellular transport of virus GO:0075733 14 0.028
response to extracellular stimulus GO:0009991 85 0.028
nitrogen compound transport GO:0071705 191 0.028
protein sumoylation GO:0016925 25 0.027
Human
regulation of ion transmembrane transport GO:0034765 132 0.027
negative regulation of ion transport GO:0043271 39 0.027
positive regulation of mrna metabolic process GO:1903313 19 0.027
posttranscriptional regulation of gene expression GO:0010608 213 0.027
Human Worm
myeloid cell differentiation GO:0030099 117 0.026
regulation of cellular response to stress GO:0080135 244 0.026
amide transport GO:0042886 76 0.026
negative regulation of protein processing GO:0010955 142 0.026
protein oligomerization GO:0051259 173 0.026
protein export from nucleus GO:0006611 29 0.026
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.026
regulation of mapk cascade GO:0043408 262 0.025
calcium ion import GO:0070509 23 0.025
regulation of cellular protein catabolic process GO:1903362 96 0.025
regulation of metal ion transport GO:0010959 120 0.025
microtubule based process GO:0007017 210 0.025
divalent metal ion transport GO:0070838 152 0.025
positive regulation of viral entry into host cell GO:0046598 3 0.025
regulation of protein secretion GO:0050708 86 0.024
intracellular transport of viral protein in host cell GO:0019060 4 0.024
negative regulation of transmembrane transport GO:0034763 29 0.024
metal ion transport GO:0030001 272 0.024
single organism carbohydrate metabolic process GO:0044723 193 0.024
regulation of tumor necrosis factor production GO:0032680 43 0.024
regulation of transmembrane transport GO:0034762 139 0.024
nervous system development GO:0007399 293 0.023
negative regulation of defense response GO:0031348 47 0.023
Human
peptide transport GO:0015833 74 0.023
epithelium migration GO:0090132 119 0.023
neuroblast proliferation GO:0007405 4 0.023
chromatin modification GO:0016568 298 0.023
secretion by cell GO:0032940 226 0.023
negative regulation of cell cycle GO:0045786 193 0.023
regulation of gene expression epigenetic GO:0040029 73 0.022
Human Worm
cellular response to oxygen containing compound GO:1901701 276 0.022
response to topologically incorrect protein GO:0035966 29 0.022
divalent inorganic cation transport GO:0072511 158 0.022
ribonucleoside monophosphate metabolic process GO:0009161 187 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.022
negative regulation of response to biotic stimulus GO:0002832 18 0.021
Human
organophosphate biosynthetic process GO:0090407 163 0.021
negative regulation of phosphorus metabolic process GO:0010563 267 0.021
macromolecule glycosylation GO:0043413 63 0.021
negative regulation of tumor necrosis factor production GO:0032720 20 0.021
angiogenesis GO:0001525 147 0.021
immune system development GO:0002520 195 0.021
regulation of phosphatase activity GO:0010921 81 0.021
negative regulation of epithelial cell migration GO:0010633 38 0.021
positive regulation of locomotion GO:0040017 186 0.021
negative regulation of transferase activity GO:0051348 124 0.021
regulation of cysteine type endopeptidase activity GO:2000116 127 0.021
regulation of protein complex assembly GO:0043254 147 0.020
negative regulation of ion transmembrane transport GO:0034766 26 0.020
anatomical structure formation involved in morphogenesis GO:0048646 284 0.020
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.020
cellular response to lipid GO:0071396 127 0.020
cranial nerve morphogenesis GO:0021602 1 0.020
membrane organization GO:0061024 292 0.020
purine nucleotide biosynthetic process GO:0006164 84 0.020
response to estrogen GO:0043627 47 0.020
regulation of protein processing GO:0070613 150 0.020
sodium ion transmembrane transport GO:0035725 59 0.020
cardiovascular system development GO:0072358 262 0.020
response to type i interferon GO:0034340 14 0.019
response to exogenous dsrna GO:0043330 10 0.019
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.019
negative regulation of protein phosphorylation GO:0001933 140 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
response to tumor necrosis factor GO:0034612 76 0.019
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.019
multi organism localization GO:1902579 14 0.019
extracellular transport GO:0006858 4 0.019
tissue migration GO:0090130 119 0.019
signal transduction by phosphorylation GO:0023014 297 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
cytokine biosynthetic process GO:0042089 37 0.018
nuclear export GO:0051168 69 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
regulation of mrna metabolic process GO:1903311 53 0.018
regulation of secretion by cell GO:1903530 177 0.017
secretion GO:0046903 254 0.017
regulation of vasculature development GO:1901342 97 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
response to abiotic stimulus GO:0009628 336 0.017
actin filament organization GO:0007015 128 0.017
positive regulation of transport GO:0051050 336 0.017
double strand break repair GO:0006302 101 0.017
negative regulation of protein catabolic process GO:0042177 59 0.017
hematopoietic or lymphoid organ development GO:0048534 186 0.017
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.017
ncrna metabolic process GO:0034660 108 0.017
Human
cellular response to biotic stimulus GO:0071216 71 0.017
negative regulation of wnt signaling pathway GO:0030178 69 0.017
posttranscriptional gene silencing GO:0016441 25 0.017
Human Worm
dna conformation change GO:0071103 113 0.016
positive regulation of cytoplasmic transport GO:1903651 82 0.016
cellular response to exogenous dsrna GO:0071360 5 0.016
regulation of transferase activity GO:0051338 355 0.016
negative regulation of protein secretion GO:0050709 29 0.016
actin cytoskeleton organization GO:0030036 207 0.016
response to interferon gamma GO:0034341 39 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
regulation of cellular component biogenesis GO:0044087 281 0.016
negative regulation of protein localization to nucleus GO:1900181 34 0.016
protein polymerization GO:0051258 71 0.016
positive regulation of protein kinase activity GO:0045860 190 0.016
nf kappab import into nucleus GO:0042348 22 0.016
defense response to bacterium GO:0042742 63 0.015
negative regulation of binding GO:0051100 57 0.015
citrate metabolic process GO:0006101 2 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
positive regulation of protein import into nucleus GO:0042307 46 0.015
purine nucleoside monophosphate metabolic process GO:0009126 186 0.015
blood vessel development GO:0001568 172 0.015
single organism nuclear import GO:1902593 104 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
regulation of nf kappab import into nucleus GO:0042345 22 0.015
glycoprotein metabolic process GO:0009100 110 0.015
isg15 protein conjugation GO:0032020 5 0.015
necroptotic process GO:0070266 16 0.014
negative regulation of dna binding GO:0043392 18 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
regulation of protein stability GO:0031647 87 0.014
regulation of protein catabolic process GO:0042176 155 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
response to growth factor GO:0070848 205 0.014
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.014
glycosyl compound catabolic process GO:1901658 413 0.014
cellular component morphogenesis GO:0032989 314 0.014
regulation of cytokine biosynthetic process GO:0042035 35 0.014
regulation of lymphocyte activation GO:0051249 103 0.014
neuron projection regeneration GO:0031102 1 0.014
lipid homeostasis GO:0055088 39 0.014
engulfment of apoptotic cell GO:0043652 2 0.013
response to oxidative stress GO:0006979 121 0.013
protein processing GO:0016485 226 0.013
glycoprotein biosynthetic process GO:0009101 91 0.013
gene silencing by mirna GO:0035195 23 0.013
Human
negative regulation of transcription factor import into nucleus GO:0042992 17 0.013
macrophage fusion GO:0034238 1 0.013
receptor metabolic process GO:0043112 81 0.013
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.013
optic nerve development GO:0021554 2 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
positive regulation of protein localization to nucleus GO:1900182 48 0.013
negative regulation of i kappab kinase nf kappab signaling GO:0043124 32 0.013
covalent chromatin modification GO:0016569 254 0.013
atp metabolic process GO:0046034 176 0.013
organophosphate catabolic process GO:0046434 430 0.012
autophagy GO:0006914 88 0.012
regulation of kinase activity GO:0043549 314 0.012
negative regulation of intracellular transport of viral material GO:1901253 2 0.012
regulation of actin cytoskeleton organization GO:0032956 116 0.012
purine nucleoside catabolic process GO:0006152 398 0.012
regulation of dna metabolic process GO:0051052 153 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
spermatid development GO:0007286 4 0.012
cellular response to external stimulus GO:0071496 111 0.012
regulation of protein kinase activity GO:0045859 289 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
stress activated mapk cascade GO:0051403 93 0.012
memory GO:0007613 3 0.012
nucleoside catabolic process GO:0009164 408 0.012
pre mirna processing GO:0031054 8 0.011
Human
purine containing compound catabolic process GO:0072523 411 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.011
positive regulation of interferon beta biosynthetic process GO:0045359 4 0.011
t cell activation GO:0042110 99 0.011
production of small rna involved in gene silencing by rna GO:0070918 13 0.011
Human
negative regulation of secretion by cell GO:1903531 52 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
neuromuscular junction development GO:0007528 3 0.011
regulation of chemokine production GO:0032642 31 0.011
chromatin assembly GO:0031497 61 0.011
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
arp2 3 complex mediated actin nucleation GO:0034314 17 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011
response to lipopolysaccharide GO:0032496 70 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
interferon gamma production GO:0032609 39 0.011
negative regulation of secretion GO:0051048 58 0.011
regulation of secretion GO:0051046 194 0.011
spermatid differentiation GO:0048515 4 0.011
lipoprotein metabolic process GO:0042157 42 0.011
cell adhesion GO:0007155 325 0.011
regulation of growth GO:0040008 165 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
organic acid biosynthetic process GO:0016053 97 0.011
positive regulation of intracellular protein transport GO:0090316 76 0.011
dsrna fragmentation GO:0031050 13 0.011
Human
maintenance of location GO:0051235 112 0.010
anatomical structure homeostasis GO:0060249 100 0.010
negative regulation of cellular protein catabolic process GO:1903363 38 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010

DDX58 disease predictions

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 431 0.040
central nervous system disease DOID:331 186 0.040
eye and adnexa disease DOID:1492 150 0.014
sensory system disease DOID:0050155 203 0.014
eye disease DOID:5614 149 0.014
aicardi goutieres syndrome DOID:0050629 7 0.011
Human
neurodegenerative disease DOID:1289 102 0.010
spinocerebellar degeneration DOID:2478 27 0.010