Mus musculus

50 known processes

Ace

angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

(Aliases: MGC117827,CD143,AW208573)

Ace biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of renal output by angiotensin GO:0002019 2 1.000
renin angiotensin regulation of aldosterone production GO:0002018 3 1.000
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1990127 1 0.995
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.994
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902238 1 0.992
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902239 1 0.988
ureteric bud development GO:0001657 94 0.986
kidney development GO:0001822 213 0.985
activation of janus kinase activity GO:0042976 2 0.980
mesonephric tubule morphogenesis GO:0072171 63 0.979
regulation of phospholipase a2 activity GO:0032429 3 0.978
negative regulation of smooth muscle cell apoptotic process GO:0034392 1 0.976
developmental pigmentation GO:0048066 40 0.973
renal system development GO:0072001 225 0.972
urogenital system development GO:0001655 261 0.971
phospholipase c activating angiotensin activated signaling pathway GO:0086097 1 0.970
renal tubule development GO:0061326 87 0.963
axon guidance GO:0007411 141 0.958
leukocyte migration GO:0050900 124 0.957
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress GO:1902218 1 0.957
drinking behavior GO:0042756 5 0.944
syncytium formation GO:0006949 43 0.943
mesonephric tubule development GO:0072164 94 0.940
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 15 0.939
pigment cell differentiation GO:0050931 27 0.932
regulation of cellular amine metabolic process GO:0033238 20 0.917
mesonephric epithelium development GO:0072163 94 0.912
superoxide metabolic process GO:0006801 27 0.909
positive regulation of cell migration GO:0030335 109 0.907
renal system process GO:0003014 48 0.904
nephron tubule development GO:0072080 84 0.896
branching involved in ureteric bud morphogenesis GO:0001658 56 0.895
development of primary sexual characteristics GO:0045137 143 0.893
Rat
axonogenesis GO:0007409 274 0.890
nephron development GO:0072006 109 0.889
mesonephros development GO:0001823 97 0.887
inflammatory response GO:0006954 244 0.887
Rat
muscle cell differentiation GO:0042692 261 0.884
ras protein signal transduction GO:0007265 77 0.882
morphogenesis of a branching epithelium GO:0061138 193 0.878
negative regulation of heart rate GO:0010459 4 0.875
morphogenesis of a branching structure GO:0001763 203 0.872
nephron epithelium morphogenesis GO:0072088 68 0.868
glomerulus development GO:0032835 40 0.854
regulation of cellular amino acid metabolic process GO:0006521 5 0.853
nephron epithelium development GO:0072009 92 0.852
g protein coupled receptor signaling pathway coupled to cgmp nucleotide second messenger GO:0007199 1 0.845
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.841
neuron projection guidance GO:0097485 141 0.838
cell chemotaxis GO:0060326 81 0.834
myotube differentiation GO:0014902 105 0.831
angiotensin activated signaling pathway GO:0038166 4 0.829
purine containing compound metabolic process GO:0072521 311 0.829
ureteric bud morphogenesis GO:0060675 62 0.826
cellular lipid metabolic process GO:0044255 323 0.814
negative regulation of systemic arterial blood pressure GO:0003085 15 0.813
t cell differentiation GO:0030217 174 0.807
kidney epithelium development GO:0072073 121 0.802
regulation of blood circulation GO:1903522 93 0.798
Fly
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.791
negative regulation of leukocyte differentiation GO:1902106 51 0.782
pigmentation GO:0043473 71 0.780
protein processing GO:0016485 163 0.778
nephron tubule morphogenesis GO:0072078 68 0.773
regulation of cholesterol esterification GO:0010872 2 0.769
drug catabolic process GO:0042737 2 0.769
establishment of protein localization to membrane GO:0090150 54 0.765
circulatory system process GO:0003013 197 0.764
camera type eye development GO:0043010 266 0.761
regulation of systemic arterial blood pressure GO:0003073 61 0.754
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.749
regulation of activation of jak2 kinase activity GO:0010534 1 0.747
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.744
regulation of peptidyl serine phosphorylation GO:0033135 39 0.742
kidney morphogenesis GO:0060993 83 0.742
regulation of neurotrophin trk receptor signaling pathway GO:0051386 4 0.740
regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902253 13 0.739
oxidation reduction process GO:0055114 342 0.731
neuroepithelial cell differentiation GO:0060563 37 0.722
apoptotic signaling pathway GO:0097190 306 0.721
purine nucleoside metabolic process GO:0042278 241 0.720
leukocyte chemotaxis GO:0030595 69 0.712
regulation of blood volume by renin angiotensin GO:0002016 7 0.705
regulation of cell migration GO:0030334 219 0.704
Rat
positive regulation of renal sodium excretion GO:0035815 2 0.703
regulation of angiotensin metabolic process GO:0060177 4 0.703
regulation of leukocyte differentiation GO:1902105 159 0.695
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.685
metanephros development GO:0001656 79 0.676
regulation of angiotensin levels in blood GO:0002002 4 0.676
small gtpase mediated signal transduction GO:0007264 97 0.675
cellular amine metabolic process GO:0044106 44 0.673
cell type specific apoptotic process GO:0097285 268 0.672
cell adhesion GO:0007155 329 0.667
response to osmotic stress GO:0006970 21 0.662
positive regulation of mesonephros development GO:0061213 20 0.660
fat soluble vitamin biosynthetic process GO:0042362 4 0.658
renal sodium excretion GO:0035812 3 0.658
leukocyte differentiation GO:0002521 342 0.658
regulation of renal sodium excretion GO:0035813 3 0.654
positive regulation of stem cell proliferation GO:2000648 59 0.649
positive regulation of rac gtpase activity GO:0032855 14 0.648
ribonucleoside metabolic process GO:0009119 245 0.644
lamellipodium organization GO:0097581 29 0.637
lipid modification GO:0030258 65 0.627
gliogenesis GO:0042063 141 0.624
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure GO:0002033 2 0.623
carbohydrate derivative biosynthetic process GO:1901137 183 0.622
metanephric nephron development GO:0072210 34 0.619
purine containing compound biosynthetic process GO:0072522 70 0.618
metanephric glomerulus development GO:0072224 13 0.613
peptidyl amino acid modification GO:0018193 336 0.613
amine metabolic process GO:0009308 45 0.611
nucleoside metabolic process GO:0009116 246 0.607
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.607
cell growth involved in cardiac muscle cell development GO:0061049 3 0.605
intracellular protein transport GO:0006886 204 0.604
regulation of hydrolase activity GO:0051336 246 0.600
myeloid leukocyte migration GO:0097529 57 0.598
regulation of protein localization GO:0032880 231 0.596
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.588
sterol esterification GO:0034434 3 0.582
peptide hormone processing GO:0016486 9 0.578
neurotransmitter transport GO:0006836 76 0.577
regulation of metanephros development GO:0072215 15 0.570
physiological cardiac muscle hypertrophy GO:0003301 3 0.570
response to organonitrogen compound GO:0010243 246 0.566
response to nutrient levels GO:0031667 109 0.562
Rat
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.562
regulation of lipid metabolic process GO:0019216 118 0.559
positive regulation of leukocyte differentiation GO:1902107 86 0.557
muscle contraction GO:0006936 101 0.557
organic hydroxy compound metabolic process GO:1901615 203 0.556
response to dexamethasone GO:0071548 8 0.554
Rat
lymphocyte apoptotic process GO:0070227 54 0.550
positive regulation of extracellular matrix organization GO:1903055 4 0.547
negative regulation of neurotrophin trk receptor signaling pathway GO:0051387 2 0.546
fatty acid metabolic process GO:0006631 121 0.544
cellular ketone metabolic process GO:0042180 84 0.542
reactive oxygen species metabolic process GO:0072593 84 0.540
extracellular matrix organization GO:0030198 147 0.540
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.533
divalent metal ion transport GO:0070838 172 0.526
Rat
signal transduction by p53 class mediator GO:0072331 51 0.526
regulation of insulin receptor signaling pathway GO:0046626 21 0.519
organelle assembly GO:0070925 177 0.514
positive regulation of protein import into nucleus GO:0042307 26 0.514
regulation of transferase activity GO:0051338 263 0.511
negative regulation of cellular protein metabolic process GO:0032269 247 0.511
establishment of protein localization to organelle GO:0072594 118 0.511
positive regulation of cell activation GO:0050867 158 0.506
cellular response to corticosteroid stimulus GO:0071384 13 0.506
positive regulation of phospholipase activity GO:0010518 3 0.503
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.503
cell substrate adhesion GO:0031589 130 0.501
superoxide anion generation GO:0042554 11 0.499
negative regulation of lymphocyte activation GO:0051250 91 0.498
positive regulation of cholesterol esterification GO:0010873 1 0.493
vesicle fusion GO:0006906 16 0.487
bone development GO:0060348 120 0.484
regulation of morphogenesis of a branching structure GO:0060688 53 0.484
glycosyl compound metabolic process GO:1901657 246 0.480
regulation of mapk cascade GO:0043408 248 0.477
regulation of nitrogen cycle metabolic process GO:1903314 1 0.476
positive regulation of metanephric glomerulus development GO:0072300 4 0.476
metanephric glomerular mesangium development GO:0072223 3 0.475
positive regulation of transferase activity GO:0051347 167 0.470
positive regulation of cell development GO:0010720 237 0.466
Rat
thymocyte apoptotic process GO:0070242 19 0.463
lymphocyte differentiation GO:0030098 242 0.460
regulation of mesonephros development GO:0061217 24 0.455
epithelial tube morphogenesis GO:0060562 303 0.454
protein localization to organelle GO:0033365 185 0.445
regulation of lymphocyte activation GO:0051249 240 0.444
modification of morphology or physiology of other organism GO:0035821 18 0.441
regulation of kidney development GO:0090183 40 0.440
melanocyte differentiation GO:0030318 25 0.439
nucleobase containing small molecule metabolic process GO:0055086 352 0.436
granulocyte chemotaxis GO:0071621 39 0.435
positive regulation of lipid metabolic process GO:0045834 40 0.432
organic hydroxy compound biosynthetic process GO:1901617 77 0.428
rhythmic process GO:0048511 174 0.419
Fly
t cell differentiation in thymus GO:0033077 77 0.414
cholesterol esterification GO:0034435 3 0.409
branching morphogenesis of an epithelial tube GO:0048754 159 0.407
positive regulation of cell death GO:0010942 224 0.407
Rat
regulation of cell activation GO:0050865 289 0.406
blood circulation GO:0008015 195 0.405
activation of rac gtpase activity GO:0032863 2 0.404
lymphocyte migration GO:0072676 26 0.402
nephron morphogenesis GO:0072028 69 0.402
negative regulation of growth GO:0045926 99 0.402
microglia development GO:0014005 2 0.401
male gamete generation GO:0048232 285 0.399
regulation of protein transport GO:0051223 163 0.396
protein maturation GO:0051604 176 0.396
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.391
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 11 0.387
angiogenesis GO:0001525 201 0.387
Rat
regulation of blood vessel size by renin angiotensin GO:0002034 5 0.387
feeding behavior GO:0007631 62 0.386
Rat
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.386
negative regulation of protein metabolic process GO:0051248 282 0.386
regulation of cellular response to growth factor stimulus GO:0090287 82 0.385
regulation of secretion by cell GO:1903530 249 0.385
limb development GO:0060173 166 0.383
calcium mediated signaling GO:0019722 46 0.381
smooth muscle contraction GO:0006939 44 0.379
positive regulation of t cell differentiation in thymus GO:0033089 13 0.372
keratinocyte migration GO:0051546 3 0.372
positive regulation of rho gtpase activity GO:0032321 41 0.367
response to vitamin d GO:0033280 3 0.366
endocrine process GO:0050886 39 0.363
central nervous system projection neuron axonogenesis GO:0021952 21 0.363
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.360
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.358
negative regulation of intracellular signal transduction GO:1902532 167 0.355
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.354
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.351
neutrophil migration GO:1990266 37 0.350
syncytium formation by plasma membrane fusion GO:0000768 42 0.349
positive regulation of lipid kinase activity GO:0090218 11 0.347
renal tubule morphogenesis GO:0061333 72 0.343
calcium ion transport GO:0006816 159 0.342
Rat
peptidyl serine phosphorylation GO:0018105 74 0.342
jak stat cascade GO:0007259 42 0.341
negative regulation of cartilage development GO:0061037 17 0.338
alcohol metabolic process GO:0006066 116 0.337
response to lipopolysaccharide GO:0032496 128 0.330
Rat
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 6 0.327
positive regulation of blood pressure GO:0045777 21 0.326
positive regulation of chondrocyte differentiation GO:0032332 13 0.326
mammary gland duct morphogenesis GO:0060603 38 0.326
chemotaxis GO:0006935 247 0.324
organonitrogen compound biosynthetic process GO:1901566 192 0.322
fat cell differentiation GO:0045444 160 0.319
cardiac muscle cell differentiation GO:0055007 69 0.318
regulation of organelle organization GO:0033043 289 0.316
negative regulation of phosphorylation GO:0042326 166 0.316
spermatogenesis GO:0007283 284 0.314
heart contraction GO:0060047 93 0.313
cation homeostasis GO:0055080 212 0.313
response to alcohol GO:0097305 48 0.312
Rat
positive regulation of kinase activity GO:0033674 155 0.311
negative regulation of cell proliferation GO:0008285 296 0.308
protein targeting GO:0006605 143 0.308
peptide transport GO:0015833 133 0.307
cytokine production GO:0001816 319 0.302
connective tissue development GO:0061448 179 0.297
ribonucleotide catabolic process GO:0009261 208 0.297
positive regulation of intracellular protein transport GO:0090316 42 0.295
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.294
cellular response to peptide hormone stimulus GO:0071375 92 0.292
regulation of glomerulus development GO:0090192 6 0.290
transmembrane transport GO:0055085 412 0.287
Rat
purine ribonucleoside metabolic process GO:0046128 241 0.285
cerebral cortex radially oriented cell migration GO:0021799 31 0.285
regulation of osteoblast differentiation GO:0045667 67 0.285
actin filament organization GO:0007015 113 0.285
positive regulation of protein secretion GO:0050714 52 0.282
immune effector process GO:0002252 321 0.281
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.280
regulation of hormone levels GO:0010817 211 0.279
neuron apoptotic process GO:0051402 142 0.278
negative regulation of t cell activation GO:0050868 65 0.275
defense response to bacterium GO:0042742 119 0.269
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.268
regulation of feeding behavior GO:0060259 3 0.266
cell proliferation in hindbrain GO:0021534 10 0.265
negative regulation of alpha beta t cell differentiation GO:0046639 12 0.265
extracellular structure organization GO:0043062 148 0.265
metal ion homeostasis GO:0055065 189 0.265
muscle system process GO:0003012 141 0.264
nucleoside phosphate metabolic process GO:0006753 338 0.263
regulation of secretion GO:0051046 274 0.263
positive regulation of protein modification process GO:0031401 299 0.262
purine ribonucleotide metabolic process GO:0009150 290 0.261
regulation of protein tyrosine kinase activity GO:0061097 17 0.261
organic cyclic compound catabolic process GO:1901361 295 0.260
dopamine metabolic process GO:0042417 23 0.259
actin cytoskeleton organization GO:0030036 220 0.258
g protein coupled receptor signaling pathway GO:0007186 243 0.258
positive regulation of protein localization to nucleus GO:1900182 30 0.255
cell differentiation involved in kidney development GO:0061005 33 0.255
regulation of activation of janus kinase activity GO:0010533 1 0.254
mammary gland morphogenesis GO:0060443 54 0.253
positive regulation of neuron differentiation GO:0045666 141 0.249
carboxylic acid transport GO:0046942 100 0.249
ribonucleoside triphosphate metabolic process GO:0009199 220 0.249
positive regulation of protein transport GO:0051222 93 0.246
regulation of ion transport GO:0043269 215 0.243
Rat
regulation of apoptotic signaling pathway GO:2001233 197 0.242
multicellular organism growth GO:0035264 161 0.242
cerebral cortex cell migration GO:0021795 44 0.242
purine nucleotide catabolic process GO:0006195 211 0.240
regulation of ossification GO:0030278 112 0.240
regulation of superoxide anion generation GO:0032928 4 0.239
regulation of phospholipase c activity GO:1900274 3 0.235
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.235
negative t cell selection GO:0043383 13 0.234
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.234
transmission of nerve impulse GO:0019226 76 0.234
positive regulation of protein kinase c activity GO:1900020 1 0.233
cellular amino acid metabolic process GO:0006520 103 0.233
sensory organ morphogenesis GO:0090596 242 0.233
meiotic cell cycle GO:0051321 122 0.232
regulation of neuron death GO:1901214 134 0.231
innate immune response GO:0045087 157 0.231
adaptive immune response GO:0002250 155 0.230
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.229
positive regulation of hydrolase activity GO:0051345 148 0.227
ossification GO:0001503 216 0.226
nucleotide metabolic process GO:0009117 332 0.225
cerebellar granule cell precursor proliferation GO:0021930 10 0.225
positive regulation of smooth muscle cell migration GO:0014911 4 0.224
striated muscle tissue development GO:0014706 293 0.223
regulation of system process GO:0044057 200 0.223
Fly
multicellular organismal signaling GO:0035637 91 0.222
germ cell development GO:0007281 185 0.221
Fly
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.221
cellular response to hormone stimulus GO:0032870 150 0.221
female gamete generation GO:0007292 74 0.219
spinal cord patterning GO:0021511 25 0.217
regulation of metal ion transport GO:0010959 106 0.215
Rat
positive regulation of kidney development GO:0090184 28 0.214
interaction with symbiont GO:0051702 14 0.213
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.212
inorganic ion transmembrane transport GO:0098660 234 0.208
organelle fission GO:0048285 170 0.207
nitrogen compound transport GO:0071705 271 0.207
cellular response to organic cyclic compound GO:0071407 87 0.204
cellular divalent inorganic cation homeostasis GO:0072503 127 0.203
aromatic compound catabolic process GO:0019439 286 0.197
regulation of protein import into nucleus GO:0042306 52 0.197
regulation of heart contraction GO:0008016 77 0.197
Fly
endocytosis GO:0006897 168 0.197
regulation of nucleotide catabolic process GO:0030811 122 0.197
phospholipid metabolic process GO:0006644 87 0.196
exploration behavior GO:0035640 21 0.193
regulation of lipase activity GO:0060191 15 0.192
vesicle organization GO:0016050 60 0.192
skeletal muscle organ development GO:0060538 163 0.191
forebrain cell migration GO:0021885 58 0.190
ribonucleotide metabolic process GO:0009259 291 0.190
negative regulation of phosphate metabolic process GO:0045936 184 0.189
response to decreased oxygen levels GO:0036293 59 0.188
Rat
microglia differentiation GO:0014004 2 0.188
t cell activation GO:0042110 289 0.187
rho protein signal transduction GO:0007266 32 0.184
regulation of vasculature development GO:1901342 88 0.184
ribose phosphate metabolic process GO:0019693 291 0.184
guanosine containing compound catabolic process GO:1901069 144 0.184
negative regulation of t cell differentiation GO:0045581 23 0.183
regulation of cytokine production GO:0001817 266 0.183
cellular chemical homeostasis GO:0055082 215 0.182
Rat
ovulation from ovarian follicle GO:0001542 9 0.181
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.180
regulation of organ morphogenesis GO:2000027 144 0.179
response to growth factor GO:0070848 198 0.179
positive regulation of intracellular transport GO:0032388 70 0.177
sensory perception GO:0007600 245 0.177
Rat
cardiac muscle tissue development GO:0048738 130 0.176
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.174
cyclic purine nucleotide metabolic process GO:0052652 43 0.173
cellular calcium ion homeostasis GO:0006874 119 0.173
steroid metabolic process GO:0008202 119 0.173
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.173
gtp catabolic process GO:0006184 143 0.172
nucleoside catabolic process GO:0009164 206 0.170
regulation of ras gtpase activity GO:0032318 88 0.169
regulation of cell motility GO:2000145 236 0.167
Rat
macromolecule glycosylation GO:0043413 55 0.167
regulation of neural precursor cell proliferation GO:2000177 70 0.166
telencephalon cell migration GO:0022029 55 0.165
anion transport GO:0006820 177 0.165
phenol containing compound metabolic process GO:0018958 60 0.163
regulation of intracellular transport GO:0032386 159 0.163
negative regulation of protein maturation GO:1903318 79 0.163
alpha beta t cell differentiation GO:0046632 69 0.162
ribonucleotide biosynthetic process GO:0009260 59 0.162
leukocyte apoptotic process GO:0071887 71 0.162
positive regulation of protein kinase activity GO:0045860 144 0.161
embryonic appendage morphogenesis GO:0035113 126 0.161
cytoplasmic transport GO:0016482 234 0.161
negative regulation of blood circulation GO:1903523 15 0.160
regulation of response to osmotic stress GO:0047484 3 0.157
floor plate morphogenesis GO:0033505 3 0.156
cerebellum morphogenesis GO:0021587 42 0.156
regulation of steroid metabolic process GO:0019218 39 0.155
male sex differentiation GO:0046661 109 0.154
Rat
response to amino acid GO:0043200 37 0.154
tissue migration GO:0090130 68 0.153
positive regulation of growth GO:0045927 104 0.153
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.153
negative regulation of immune system process GO:0002683 209 0.153
brown fat cell differentiation GO:0050873 36 0.153
protein import into nucleus GO:0006606 95 0.152
positive regulation of ras gtpase activity GO:0032320 65 0.151
erbb signaling pathway GO:0038127 32 0.149
forebrain development GO:0030900 302 0.148
bone morphogenesis GO:0060349 78 0.147
action potential GO:0001508 78 0.147
endothelial cell differentiation GO:0045446 41 0.147
gland development GO:0048732 330 0.146
response to fructose GO:0009750 2 0.146
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.146
organophosphate biosynthetic process GO:0090407 122 0.146
nuclear division GO:0000280 158 0.145
central nervous system neuron development GO:0021954 67 0.145
glial cell development GO:0021782 54 0.144
central nervous system neuron differentiation GO:0021953 162 0.141
organ growth GO:0035265 117 0.141
regulation of norepinephrine secretion GO:0014061 2 0.140
metanephric nephron epithelium development GO:0072243 19 0.140
morphogenesis of an epithelial bud GO:0060572 18 0.139
nucleoside triphosphate metabolic process GO:0009141 230 0.138
regulation of protein kinase activity GO:0045859 232 0.138
regulation of membrane potential GO:0042391 192 0.138
response to peptide hormone GO:0043434 127 0.137
antigen processing and presentation GO:0019882 47 0.137
neutrophil chemotaxis GO:0030593 36 0.135
protein localization to membrane GO:0072657 108 0.135
negative regulation of blood pressure GO:0045776 22 0.135
development of primary male sexual characteristics GO:0046546 88 0.134
Rat
glial cell differentiation GO:0010001 131 0.133
epithelial cell proliferation GO:0050673 174 0.132
positive regulation of protein phosphorylation GO:0001934 242 0.131
negative regulation of lymphocyte differentiation GO:0045620 32 0.131
negative regulation of cell development GO:0010721 169 0.131
renal system process involved in regulation of blood volume GO:0001977 4 0.130
defense response to other organism GO:0098542 197 0.130
response to insulin GO:0032868 100 0.129
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.129
response to peptide GO:1901652 136 0.129
purine nucleotide metabolic process GO:0006163 302 0.129
skeletal system development GO:0001501 356 0.128
regulation of gtp catabolic process GO:0033124 113 0.128
metanephros morphogenesis GO:0003338 24 0.127
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.127
cation transport GO:0006812 399 0.127
Rat
response to organic cyclic compound GO:0014070 198 0.124
Rat
negative regulation of protein modification process GO:0031400 163 0.124
response to drug GO:0042493 75 0.123
Rat
t cell migration GO:0072678 19 0.122
embryonic organ morphogenesis GO:0048562 276 0.122
appendage development GO:0048736 166 0.122
cardiac cell development GO:0055006 41 0.122
positive regulation of neuron apoptotic process GO:0043525 25 0.121
cellular response to abiotic stimulus GO:0071214 56 0.121
meiotic nuclear division GO:0007126 115 0.121
ovulation GO:0030728 15 0.120
negative regulation of protein phosphorylation GO:0001933 126 0.120
cartilage development GO:0051216 140 0.120
regulation of kinase activity GO:0043549 249 0.119
carbohydrate biosynthetic process GO:0016051 74 0.119
purine ribonucleotide catabolic process GO:0009154 208 0.119
neuron death GO:0070997 154 0.118
regulation of metanephric glomerulus development GO:0072298 5 0.118
lung development GO:0030324 164 0.118
Rat
regulation of muscle system process GO:0090257 80 0.117
peptidyl tyrosine phosphorylation GO:0018108 143 0.117
nuclear import GO:0051170 95 0.116
mapk cascade GO:0000165 281 0.115
cellular response to cytokine stimulus GO:0071345 189 0.115
amine transport GO:0015837 21 0.115
epithelial cell migration GO:0010631 63 0.114
regulation of protein kinase c activity GO:1900019 1 0.114
negative regulation of cell growth GO:0030308 44 0.113
lipid transport GO:0006869 98 0.113
striated muscle cell development GO:0055002 125 0.113
regulation of epithelial cell migration GO:0010632 35 0.113
activation of ras gtpase activity GO:0032856 11 0.112
cerebellar cortex development GO:0021695 48 0.112
organic acid transport GO:0015849 101 0.111
chondrocyte differentiation GO:0002062 72 0.110
purine ribonucleoside catabolic process GO:0046130 205 0.109
catecholamine metabolic process GO:0006584 30 0.109
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.108
cellular response to organonitrogen compound GO:0071417 145 0.107
negative regulation of ras protein signal transduction GO:0046580 18 0.107
response to monosaccharide GO:0034284 67 0.107
Rat
activation of rho gtpase activity GO:0032862 7 0.106
catecholamine secretion GO:0050432 15 0.106
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.106

Ace disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
hypertension DOID:10763 0 0.997
artery disease DOID:0050828 0 0.997
disease of anatomical entity DOID:7 0 0.997
vascular disease DOID:178 0 0.997
essential hypertension DOID:10825 0 0.997
cardiovascular system disease DOID:1287 0 0.997
nervous system disease DOID:863 0 0.380
nephronophthisis DOID:12712 0 0.343
disease of metabolism DOID:0014667 0 0.275
inherited metabolic disorder DOID:655 0 0.275
sensory system disease DOID:0050155 0 0.110