Mus musculus

214 known processes

Pparg

peroxisome proliferator activated receptor gamma

(Aliases: PPARgamma2,PPARgamma,PPAR-gamma2,PPAR-gamma,Nr1c3)

Pparg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of fatty acid metabolic process GO:0019217 28 1.000
Mouse Rat
acylglycerol catabolic process GO:0046464 11 1.000
acylglycerol metabolic process GO:0006639 55 1.000
lipid catabolic process GO:0016042 69 1.000
Mouse
neutral lipid metabolic process GO:0006638 57 1.000
triglyceride metabolic process GO:0006641 51 1.000
fatty acid metabolic process GO:0006631 121 1.000
Mouse Rat
triglyceride catabolic process GO:0019433 9 1.000
regulation of fatty acid oxidation GO:0046320 10 0.999
Mouse Rat
intestinal absorption GO:0050892 13 0.999
Mouse
lipid modification GO:0030258 65 0.999
Mouse Rat
regulation of lipid catabolic process GO:0050994 15 0.998
glycerolipid metabolic process GO:0046486 122 0.998
lipid storage GO:0019915 36 0.998
Human
positive regulation of triglyceride metabolic process GO:0090208 9 0.998
intestinal cholesterol absorption GO:0030299 5 0.998
monocarboxylic acid catabolic process GO:0072329 27 0.998
Mouse
cellular response to peptide GO:1901653 92 0.997
brown fat cell differentiation GO:0050873 36 0.997
monocarboxylic acid metabolic process GO:0032787 191 0.996
Mouse Rat
regulation of the force of heart contraction by chemical signal GO:0003057 5 0.996
negative regulation of lipid catabolic process GO:0050995 6 0.996
negative regulation of lipid metabolic process GO:0045833 30 0.995
glycerolipid catabolic process GO:0046503 16 0.995
cellular ketone metabolic process GO:0042180 84 0.994
Mouse Rat
carbohydrate metabolic process GO:0005975 230 0.994
Mouse
regulation of carbohydrate metabolic process GO:0006109 75 0.994
Mouse
regulation of triglyceride metabolic process GO:0090207 17 0.993
cellular lipid metabolic process GO:0044255 323 0.993
Mouse Rat
lipid oxidation GO:0034440 29 0.993
Mouse Rat
regulation of cellular ketone metabolic process GO:0010565 66 0.992
Mouse Rat
fatty acid oxidation GO:0019395 28 0.990
Mouse Rat
generation of precursor metabolites and energy GO:0006091 103 0.990
response to alkaloid GO:0043279 34 0.990
Rat
cellular lipid catabolic process GO:0044242 52 0.989
Mouse
monosaccharide metabolic process GO:0005996 106 0.988
Mouse
regulation of insulin receptor signaling pathway GO:0046626 21 0.987
neutral lipid catabolic process GO:0046461 11 0.986
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.986
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.985
response to peptide hormone GO:0043434 127 0.978
response to organic cyclic compound GO:0014070 198 0.977
regulation of cellular amino acid metabolic process GO:0006521 5 0.976
Mouse
regulation of sequestering of triglyceride GO:0010889 6 0.975
Human
glucose metabolic process GO:0006006 92 0.970
Mouse
triglyceride biosynthetic process GO:0019432 17 0.970
regulation of cellular catabolic process GO:0031329 242 0.969
glycerolipid biosynthetic process GO:0045017 50 0.969
positive regulation of triglyceride catabolic process GO:0010898 3 0.968
pyruvate metabolic process GO:0006090 28 0.968
glycolytic process GO:0006096 20 0.968
triglyceride mobilization GO:0006642 5 0.966
diacylglycerol metabolic process GO:0046339 6 0.966
cellular carbohydrate metabolic process GO:0044262 119 0.964
Mouse
positive regulation of lipid metabolic process GO:0045834 40 0.962
Mouse Rat
regulation of appetite GO:0032098 12 0.962
Mouse
acylglycerol homeostasis GO:0055090 16 0.960
Zebrafish
glucose import GO:0046323 32 0.958
negative regulation of reactive oxygen species biosynthetic process GO:1903427 0 0.957
regulation of cellular amine metabolic process GO:0033238 20 0.956
Mouse
regulation of blood coagulation GO:0030193 28 0.956
hexose metabolic process GO:0019318 98 0.955
Mouse
single organism nuclear import GO:1902593 95 0.953
regulation of lipid metabolic process GO:0019216 118 0.950
Mouse Rat
response to extracellular stimulus GO:0009991 127 0.946
Mouse Rat
neuronal action potential GO:0019228 54 0.945
Mouse
response to ammonium ion GO:0060359 21 0.944
reactive nitrogen species metabolic process GO:2001057 0 0.942
positive regulation of cellular amine metabolic process GO:0033240 5 0.941
Mouse
regulation of hormone secretion GO:0046883 88 0.941
positive regulation of lipid catabolic process GO:0050996 6 0.941
gluconeogenesis GO:0006094 39 0.940
Mouse
defense response to other organism GO:0098542 197 0.938
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 2 0.933
small molecule catabolic process GO:0044282 71 0.931
Mouse
acylglycerol biosynthetic process GO:0046463 18 0.931
regulation of fat cell differentiation GO:0045598 81 0.931
response to nutrient levels GO:0031667 109 0.930
Mouse Rat
lactation GO:0007595 25 0.928
Mouse
sterol metabolic process GO:0016125 58 0.926
regulation of intestinal cholesterol absorption GO:0030300 4 0.925
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.922
carbohydrate homeostasis GO:0033500 128 0.921
Human
fatty acid catabolic process GO:0009062 25 0.921
Mouse
sequestering of triglyceride GO:0030730 6 0.920
Human
regulation of the force of heart contraction GO:0002026 17 0.920
lipid transport GO:0006869 98 0.917
hexose transport GO:0008645 56 0.917
serotonin transport GO:0006837 11 0.913
positive regulation of cellular catabolic process GO:0031331 148 0.913
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.912
purine nucleotide biosynthetic process GO:0006164 65 0.911
regulation of kinase activity GO:0043549 249 0.911
lipid localization GO:0010876 126 0.909
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.907
regulation of generation of precursor metabolites and energy GO:0043467 38 0.905
regulation of gluconeogenesis GO:0006111 30 0.905
Mouse
regulation of nucleotide biosynthetic process GO:0030808 34 0.904
cellular carbohydrate catabolic process GO:0044275 15 0.903
negative regulation of serotonin secretion GO:0014063 2 0.903
fat cell differentiation GO:0045444 160 0.903
protein localization to nucleus GO:0034504 121 0.903
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.895
Mouse
response to insulin GO:0032868 100 0.894
gland development GO:0048732 330 0.889
Mouse
ribonucleotide biosynthetic process GO:0009260 59 0.889
wound healing GO:0042060 157 0.886
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.884
Human
drug catabolic process GO:0042737 2 0.882
carbohydrate transport GO:0008643 62 0.882
positive regulation of protein modification process GO:0031401 299 0.881
positive regulation of cholesterol transport GO:0032376 9 0.879
positive regulation of glial cell proliferation GO:0060252 4 0.877
positive regulation of protein phosphorylation GO:0001934 242 0.874
insulin receptor signaling pathway GO:0008286 49 0.871
cytoplasmic transport GO:0016482 234 0.869
steroid metabolic process GO:0008202 119 0.869
Mouse
positive regulation of apoptotic process GO:0043065 217 0.868
Human Mouse Rat
regulation of hormone levels GO:0010817 211 0.868
organic hydroxy compound transport GO:0015850 93 0.866
regulation of carbohydrate catabolic process GO:0043470 12 0.866
monosaccharide biosynthetic process GO:0046364 44 0.863
Mouse
response to cocaine GO:0042220 14 0.861
organic hydroxy compound metabolic process GO:1901615 203 0.860
Mouse
neutral lipid biosynthetic process GO:0046460 18 0.855
regulation of membrane potential GO:0042391 192 0.853
Mouse
protein localization to organelle GO:0033365 185 0.850
white fat cell differentiation GO:0050872 15 0.848
muscle adaptation GO:0043500 39 0.841
negative regulation of secretion by cell GO:1903531 54 0.838
glucose homeostasis GO:0042593 128 0.835
Human
monoamine transport GO:0015844 33 0.835
regulation of purine nucleotide metabolic process GO:1900542 169 0.834
g protein coupled receptor internalization GO:0002031 3 0.832
regulation of lipid storage GO:0010883 20 0.831
Human
regulation of protein targeting GO:1903533 61 0.831
amine metabolic process GO:0009308 45 0.830
Mouse
response to corticosterone GO:0051412 1 0.829
catecholamine metabolic process GO:0006584 30 0.828
regulation of epithelial cell proliferation GO:0050678 141 0.820
Mouse
regulation of defense response GO:0031347 233 0.816
Human Rat
cholesterol transport GO:0030301 38 0.815
cellular amine metabolic process GO:0044106 44 0.813
Mouse
ribose phosphate biosynthetic process GO:0046390 59 0.811
protein modification by small protein conjugation GO:0032446 187 0.810
cholesterol metabolic process GO:0008203 56 0.805
positive regulation of carbohydrate metabolic process GO:0045913 30 0.804
Mouse
response to decreased oxygen levels GO:0036293 59 0.799
Mouse
protein import into nucleus GO:0006606 95 0.797
energy derivation by oxidation of organic compounds GO:0015980 77 0.795
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.795
Human
establishment of protein localization to organelle GO:0072594 118 0.783
organophosphate biosynthetic process GO:0090407 122 0.782
positive regulation of glycolytic process GO:0045821 4 0.782
circadian rhythm GO:0007623 114 0.778
Mouse
response to organonitrogen compound GO:0010243 246 0.778
oxidation reduction process GO:0055114 342 0.778
Mouse Rat
cellular response to organonitrogen compound GO:0071417 145 0.777
histamine induced gastric acid secretion GO:0001697 1 0.777
regulation of peptide hormone secretion GO:0090276 75 0.776
negative regulation of release of cytochrome c from mitochondria GO:0090201 6 0.775
fatty acid beta oxidation GO:0006635 16 0.769
Mouse
negative regulation of carbohydrate metabolic process GO:0045912 19 0.768
long term synaptic potentiation GO:0060291 25 0.765
negative regulation of fatty acid metabolic process GO:0045922 10 0.758
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.753
Mouse
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.752
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.752
regulation of endothelial cell proliferation GO:0001936 23 0.746
peptidyl amino acid modification GO:0018193 336 0.744
monosaccharide transport GO:0015749 58 0.732
development of primary sexual characteristics GO:0045137 143 0.731
lipid biosynthetic process GO:0008610 179 0.728
Mouse
creatinine metabolic process GO:0046449 3 0.728
cholesterol homeostasis GO:0042632 44 0.727
response to drug GO:0042493 75 0.726
Rat
metal ion homeostasis GO:0055065 189 0.724
Mouse
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.724
cellular amino acid metabolic process GO:0006520 103 0.723
Mouse
regulation of triglyceride catabolic process GO:0010896 5 0.720
positive regulation of dendrite development GO:1900006 21 0.716
ammonia assimilation cycle GO:0019676 2 0.713
Mouse
cellular ion homeostasis GO:0006873 165 0.711
Mouse
positive regulation of transferase activity GO:0051347 167 0.709
regulation of myeloid cell differentiation GO:0045637 96 0.704
cyclic purine nucleotide metabolic process GO:0052652 43 0.704
regulation of lipid biosynthetic process GO:0046890 54 0.704
Mouse
cellular response to temperature stimulus GO:0071502 2 0.697
regulation of protein serine threonine kinase activity GO:0071900 157 0.694
positive regulation of fatty acid oxidation GO:0046321 4 0.691
Mouse Rat
mammary gland epithelium development GO:0061180 65 0.681
Mouse
autophagy GO:0006914 45 0.680
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.680
digestion GO:0007586 40 0.679
Mouse
cellular response to hypoxia GO:0071456 17 0.678
Mouse
regulation of androgen receptor signaling pathway GO:0060765 3 0.677
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.674
Mouse
gastrin induced gastric acid secretion GO:0001698 1 0.671
regulation of reactive oxygen species metabolic process GO:2000377 40 0.667
peptidyl tyrosine phosphorylation GO:0018108 143 0.666
regulation of peptide transport GO:0090087 91 0.666
ossification GO:0001503 216 0.664
positive regulation of kinase activity GO:0033674 155 0.664
regulation of glycolytic process GO:0006110 10 0.663
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.663
cholesterol esterification GO:0034435 3 0.659
amide transport GO:0042886 138 0.659
positive regulation of lipid storage GO:0010884 10 0.658
carboxylic acid catabolic process GO:0046395 51 0.658
Mouse
positive regulation of mapk cascade GO:0043410 170 0.657
regulation of establishment of protein localization GO:0070201 181 0.657
multicellular organism growth GO:0035264 161 0.656
regulation of blood circulation GO:1903522 93 0.652
cation transport GO:0006812 399 0.652
Mouse
regulation of natural killer cell differentiation GO:0032823 11 0.646
carbohydrate catabolic process GO:0016052 32 0.646
organic hydroxy compound biosynthetic process GO:1901617 77 0.645
Mouse
positive regulation of atp biosynthetic process GO:2001171 2 0.643
urogenital system development GO:0001655 261 0.642
multicellular organismal homeostasis GO:0048871 164 0.641
response to lithium ion GO:0010226 10 0.641
purine containing compound biosynthetic process GO:0072522 70 0.640
muscle system process GO:0003012 141 0.639
anatomical structure homeostasis GO:0060249 145 0.638
protein import GO:0017038 101 0.633
regulation of nucleoside metabolic process GO:0009118 130 0.632
regulation of p38mapk cascade GO:1900744 3 0.626
sensitization GO:0046960 2 0.623
positive regulation of chromatin modification GO:1903310 28 0.621
lipid homeostasis GO:0055088 63 0.619
Zebrafish
purine ribonucleotide biosynthetic process GO:0009152 59 0.617
negative regulation of systemic arterial blood pressure GO:0003085 15 0.617
defense response to bacterium GO:0042742 119 0.617
release of cytochrome c from mitochondria GO:0001836 23 0.616
regulation of monooxygenase activity GO:0032768 7 0.615
Mouse
cellular response to external stimulus GO:0071496 88 0.615
Rat
positive regulation of metalloenzyme activity GO:0048554 3 0.612
conditioned taste aversion GO:0001661 4 0.607
alpha amino acid metabolic process GO:1901605 59 0.607
Mouse
cellular response to inorganic substance GO:0071241 37 0.606
response to amphetamine GO:0001975 16 0.606
positive regulation of ossification GO:0045778 47 0.605
organic acid catabolic process GO:0016054 51 0.604
Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.603
positive regulation of programmed cell death GO:0043068 218 0.603
Human Mouse Rat
tissue remodeling GO:0048771 102 0.603
Mouse
regulation of cell migration GO:0030334 219 0.603
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.600
dopamine metabolic process GO:0042417 23 0.599
striated muscle hypertrophy GO:0014897 24 0.595
negative regulation of phosphorylation GO:0042326 166 0.593
negative regulation of phosphorus metabolic process GO:0010563 184 0.592
positive regulation of cholesterol efflux GO:0010875 9 0.592
glucose transport GO:0015758 56 0.591
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.591
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.589
hormone secretion GO:0046879 128 0.586
negative regulation of cellular response to oxidative stress GO:1900408 10 0.585
cellular response to starvation GO:0009267 57 0.585
regulation of body fluid levels GO:0050878 162 0.581
Mouse
cellular chemical homeostasis GO:0055082 215 0.580
Mouse
fibroblast migration GO:0010761 21 0.580
negative regulation of fat cell differentiation GO:0045599 36 0.580
epithelial cell proliferation GO:0050673 174 0.579
Mouse
regulation of nitric oxide synthase activity GO:0050999 6 0.579
positive regulation of organelle organization GO:0010638 128 0.576
phenol containing compound metabolic process GO:0018958 60 0.572
regulation of fatty acid beta oxidation GO:0031998 1 0.566
regulation of hydrolase activity GO:0051336 246 0.565
Human
regulation of peptide secretion GO:0002791 77 0.559
regulation of response to wounding GO:1903034 189 0.559
Rat
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.559
lipid particle organization GO:0034389 7 0.557
sterol transport GO:0015918 38 0.555
plasma lipoprotein particle clearance GO:0034381 13 0.553
positive regulation of fat cell differentiation GO:0045600 32 0.553
peptide hormone secretion GO:0030072 109 0.552
positive regulation of leukocyte proliferation GO:0070665 73 0.551
nuclear import GO:0051170 95 0.550
positive regulation of endothelial cell proliferation GO:0001938 17 0.549
regulation of coagulation GO:0050818 31 0.545
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.545
regulation of myeloid leukocyte differentiation GO:0002761 58 0.537
corticotropin releasing hormone secretion GO:0043396 2 0.535
nucleoside phosphate biosynthetic process GO:1901293 79 0.535
cellular divalent inorganic cation homeostasis GO:0072503 127 0.532
Mouse
negative regulation of kinase activity GO:0033673 81 0.530
bone resorption GO:0045453 38 0.527
response to tumor necrosis factor GO:0034612 26 0.527
positive regulation of fatty acid metabolic process GO:0045923 8 0.525
Mouse Rat
positive regulation of sterol transport GO:0032373 9 0.522
serotonin receptor signaling pathway GO:0007210 8 0.521
regulation of wound healing GO:0061041 40 0.520
peptide transport GO:0015833 133 0.519
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.518
cellular metal ion homeostasis GO:0006875 151 0.518
Mouse
regulation of presynaptic membrane organization GO:1901629 3 0.515
positive regulation of macroautophagy GO:0016239 3 0.515
interleukin 18 mediated signaling pathway GO:0035655 2 0.514
glycosyl compound metabolic process GO:1901657 246 0.510
positive regulation of nucleotide metabolic process GO:0045981 114 0.509
nucleocytoplasmic transport GO:0006913 139 0.507
carbohydrate derivative biosynthetic process GO:1901137 183 0.507
response to testosterone GO:0033574 3 0.506
organonitrogen compound catabolic process GO:1901565 264 0.503
negative regulation of cellular amine metabolic process GO:0033239 1 0.502
protein targeting GO:0006605 143 0.502
regulation of mapk cascade GO:0043408 248 0.500
cellular response to insulin stimulus GO:0032869 78 0.498
operant conditioning GO:0035106 2 0.498
organic acid transport GO:0015849 101 0.494
striated muscle tissue development GO:0014706 293 0.494
notochord cell development GO:0060035 1 0.493
inflammatory response GO:0006954 244 0.490
Rat
ear development GO:0043583 200 0.489
regulation of leukocyte differentiation GO:1902105 159 0.487
smooth muscle contraction GO:0006939 44 0.485
purine nucleoside metabolic process GO:0042278 241 0.482
negative regulation of phosphate metabolic process GO:0045936 184 0.482
regulation of triglyceride biosynthetic process GO:0010866 10 0.481
negative regulation of protein phosphorylation GO:0001933 126 0.480
sterol homeostasis GO:0055092 45 0.478
response to food GO:0032094 17 0.476
Mouse
regulation of secretion GO:0051046 274 0.476
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.476
blood coagulation GO:0007596 76 0.475
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 8 0.474
lipid digestion GO:0044241 7 0.472
regulation of glucose metabolic process GO:0010906 60 0.470
Mouse
regulation of hemostasis GO:1900046 28 0.467
response to starvation GO:0042594 65 0.467
Rat
dopamine transport GO:0015872 15 0.466
cellular response to increased oxygen levels GO:0036295 1 0.465
Rat
toxin transport GO:1901998 38 0.465
positive regulation of nitric oxide synthase activity GO:0051000 2 0.464
positive regulation of camp metabolic process GO:0030816 19 0.463
cellular response to x ray GO:0071481 2 0.461
nuclear transport GO:0051169 139 0.459
response to inorganic substance GO:0010035 96 0.457
response to oxygen levels GO:0070482 62 0.456
Mouse Rat
myeloid cell differentiation GO:0030099 233 0.453
Human
cation homeostasis GO:0055080 212 0.451
Mouse
internal protein amino acid acetylation GO:0006475 42 0.451
purine nucleotide metabolic process GO:0006163 302 0.449
cellular calcium ion homeostasis GO:0006874 119 0.448
Mouse
nitrogen compound transport GO:0071705 271 0.447
response to interleukin 15 GO:0070672 3 0.446
anagen GO:0042640 13 0.445
Mouse
negative regulation of secretion GO:0051048 61 0.444
response to epidermal growth factor GO:0070849 4 0.442
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.442
hemostasis GO:0007599 78 0.441
positive regulation of creb transcription factor activity GO:0032793 4 0.440
positive regulation of presynaptic membrane organization GO:1901631 1 0.438
reverse cholesterol transport GO:0043691 6 0.436
coagulation GO:0050817 78 0.436
regulation of cellular carbohydrate catabolic process GO:0043471 12 0.435
regulation of secretion by cell GO:1903530 249 0.435
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.434
regulation of myeloid cell apoptotic process GO:0033032 19 0.434
regulation of muscle tissue development GO:1901861 97 0.434
regulation of muscle contraction GO:0006937 49 0.433
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.433
divalent inorganic cation homeostasis GO:0072507 138 0.431
Mouse
response to steroid hormone GO:0048545 56 0.430
Rat
multi organism behavior GO:0051705 62 0.430
vasodilation GO:0042311 28 0.429
regulation of autophagy GO:0010506 30 0.426
regulation of cyclase activity GO:0031279 13 0.425
taurine metabolic process GO:0019530 4 0.424
organic anion transport GO:0015711 137 0.423
glutamine family amino acid metabolic process GO:0009064 15 0.423
Mouse
negative regulation of anoikis GO:2000811 2 0.419
regulation of muscle adaptation GO:0043502 31 0.418
cellular response to acid chemical GO:0071229 68 0.418
Mouse Rat
positive regulation of glucose import in response to insulin stimulus GO:2001275 5 0.417
regulation of dopamine metabolic process GO:0042053 10 0.416
cardiac muscle hypertrophy GO:0003300 23 0.415
response to hypoxia GO:0001666 58 0.415
Mouse
positive regulation of gtpase activity GO:0043547 85 0.414
negative regulation of growth GO:0045926 99 0.412
Rat
serotonin uptake GO:0051610 3 0.411
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.409
multicellular organismal signaling GO:0035637 91 0.409
Mouse
negative regulation of glycolytic process GO:0045820 4 0.408
divalent inorganic cation transport GO:0072511 178 0.406
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.406
reproductive behavior GO:0019098 32 0.402
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.399
Mouse
negative regulation of ion transport GO:0043271 28 0.394
ribonucleoside triphosphate metabolic process GO:0009199 220 0.392
maternal process involved in female pregnancy GO:0060135 32 0.391
Mouse
regulation of transcription involved in cell fate commitment GO:0060850 15 0.390
nitric oxide biosynthetic process GO:0006809 25 0.389
nucleoside metabolic process GO:0009116 246 0.388
response to peptide GO:1901652 136 0.386
positive regulation of blood circulation GO:1903524 22 0.385
regulation of ion transport GO:0043269 215 0.384
anion transport GO:0006820 177 0.379
regulation of organelle organization GO:0033043 289 0.379
regulation of glucagon secretion GO:0070092 2 0.377
myeloid leukocyte differentiation GO:0002573 119 0.376
Human
endothelial cell proliferation GO:0001935 27 0.368
p38mapk cascade GO:0038066 4 0.365
cell growth involved in cardiac muscle cell development GO:0061049 3 0.365
regulation of protein transport GO:0051223 163 0.364
macroautophagy GO:0016236 21 0.362
adrenergic receptor signaling pathway GO:0071875 13 0.361
ras protein signal transduction GO:0007265 77 0.361
regulation of growth of symbiont in host GO:0044126 19 0.360
positive regulation of growth GO:0045927 104 0.360
positive regulation of vasoconstriction GO:0045907 4 0.359
regulation of response to food GO:0032095 10 0.358
Mouse
regulation of protein import into nucleus GO:0042306 52 0.357
regulation of transferase activity GO:0051338 263 0.356
Rat
regulation of ras gtpase activity GO:0032318 88 0.354
mapk cascade GO:0000165 281 0.353
cyclic nucleotide mediated signaling GO:0019935 18 0.351
plasma membrane long chain fatty acid transport GO:0015911 1 0.351
multi multicellular organism process GO:0044706 109 0.346
Mouse
negative regulation of sterol transport GO:0032372 4 0.345
sodium ion transport GO:0006814 73 0.344
positive regulation of apoptotic signaling pathway GO:2001235 95 0.344
positive regulation of nucleoside metabolic process GO:0045979 91 0.341
alcohol metabolic process GO:0006066 116 0.341
Mouse
innate immune response GO:0045087 157 0.339
Human
glutamine family amino acid catabolic process GO:0009065 5 0.338
response to dexamethasone GO:0071548 8 0.338
positive regulation of protein kinase activity GO:0045860 144 0.338
cellular response to lipid GO:0071396 145 0.335
Mouse Rat
positive regulation of alkaline phosphatase activity GO:0010694 3 0.333
digestive tract development GO:0048565 190 0.332
maternal placenta development GO:0001893 20 0.332
positive regulation of protein transport GO:0051222 93 0.331
regulation of carbohydrate biosynthetic process GO:0043255 40 0.329
Mouse
regulation of osteoclast differentiation GO:0045670 36 0.328
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.327
peptide secretion GO:0002790 114 0.326
organonitrogen compound biosynthetic process GO:1901566 192 0.325
regulation of dna templated transcription in response to stress GO:0043620 9 0.324
small gtpase mediated signal transduction GO:0007264 97 0.324
glucagon secretion GO:0070091 3 0.324
response to lipopolysaccharide GO:0032496 128 0.324
receptor mediated endocytosis GO:0006898 51 0.324
positive regulation of synaptic transmission glutamatergic GO:0051968 8 0.321
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.321
regulation of chromatin modification GO:1903308 57 0.320
response to defense related nitric oxide production by other organism involved in symbiotic interaction GO:0052551 2 0.318
regulation of cholesterol transport GO:0032374 17 0.318
regulation of steroid biosynthetic process GO:0050810 26 0.318
Mouse
epidermis development GO:0008544 187 0.317
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.315
temperature homeostasis GO:0001659 26 0.314
positive regulation of cytokine production GO:0001819 174 0.313
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.312
response to estrogen GO:0043627 24 0.312
Rat
membrane raft assembly GO:0001765 3 0.307
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.305
phospholipase c activating dopamine receptor signaling pathway GO:0060158 5 0.303
hair follicle development GO:0001942 85 0.303
Mouse
peptidyl tyrosine modification GO:0018212 145 0.302
fatty acid transmembrane transport GO:1902001 1 0.301
nitrogen cycle metabolic process GO:0071941 3 0.301
Mouse
hormone metabolic process GO:0042445 86 0.301
drug metabolic process GO:0017144 4 0.301
glial cell differentiation GO:0010001 131 0.301
Rat
intracellular protein transport GO:0006886 204 0.298
isoleucine metabolic process GO:0006549 4 0.297
cell type specific apoptotic process GO:0097285 268 0.297
polysaccharide metabolic process GO:0005976 39 0.295
modification by symbiont of host morphology or physiology GO:0044003 4 0.294
regulation of lyase activity GO:0051339 13 0.293
carboxylic acid transport GO:0046942 100 0.292
phospholipid metabolic process GO:0006644 87 0.291
negative regulation of intracellular signal transduction GO:1902532 167 0.291
regulation of transmembrane transport GO:0034762 128 0.289
activation of adenylate cyclase activity GO:0007190 4 0.289
stem cell development GO:0048864 219 0.288
habituation GO:0046959 3 0.287
endocytosis GO:0006897 168 0.286
Rat
regulation of cell activation GO:0050865 289 0.285
ribonucleotide metabolic process GO:0009259 291 0.285
ribonucleoside metabolic process GO:0009119 245 0.285
exogenous drug catabolic process GO:0042738 1 0.284
serotonin metabolic process GO:0042428 8 0.284
regulation of sodium ion transport GO:0002028 29 0.281
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.281
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.280
negative regulation of apoptotic signaling pathway GO:2001234 104 0.279
reactive oxygen species biosynthetic process GO:1903409 8 0.278
regulation of camp biosynthetic process GO:0030817 25 0.276
negative regulation of platelet derived growth factor receptor beta signaling pathway GO:2000587 2 0.275
ion transmembrane transport GO:0034220 361 0.275
response to growth hormone GO:0060416 7 0.275
positive regulation of transcription by galactose GO:0000411 1 0.275

Pparg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.985
Human
nutrition disease DOID:374 0 0.458
Human
acquired metabolic disease DOID:0060158 0 0.458
Human
overnutrition DOID:654 0 0.344
Human