Mus musculus

0 known processes

Tab2

TGF-beta activated kinase 1/MAP3K7 binding protein 2

(Aliases: A530078N03Rik,Map3k7ip2,1110030N06Rik,mKIAA0733)

Tab2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
activation of nf kappab inducing kinase activity GO:0007250 4 0.919
positive regulation of protein modification process GO:0031401 299 0.714
Human
negative regulation of ripoptosome assembly involved in necroptotic process GO:1902443 3 0.572
positive regulation of mapk cascade GO:0043410 170 0.490
covalent chromatin modification GO:0016569 163 0.475
peptidyl amino acid modification GO:0018193 336 0.468
positive regulation of protein phosphorylation GO:0001934 242 0.430
Human
regulation of transferase activity GO:0051338 263 0.429
Human
chromatin organization GO:0006325 206 0.392
chromatin modification GO:0016568 187 0.374
regulation of defense response GO:0031347 233 0.369
nucleoside phosphate catabolic process GO:1901292 222 0.344
purine ribonucleoside catabolic process GO:0046130 205 0.343
regulation of purine nucleotide metabolic process GO:1900542 169 0.336
i kappab kinase nf kappab signaling GO:0007249 85 0.335
Human
regulation of antibacterial peptide production GO:0002786 1 0.334
purine nucleoside triphosphate metabolic process GO:0009144 226 0.332
ribonucleoside triphosphate catabolic process GO:0009203 199 0.331
gtp metabolic process GO:0046039 144 0.324
ras protein signal transduction GO:0007265 77 0.312
establishment of organelle localization GO:0051656 122 0.302
negative regulation of intracellular signal transduction GO:1902532 167 0.290
nucleoside phosphate metabolic process GO:0006753 338 0.279
methylation GO:0032259 134 0.271
histone modification GO:0016570 159 0.245
purine nucleoside catabolic process GO:0006152 205 0.228
cellular amino acid metabolic process GO:0006520 103 0.227
digestive system development GO:0055123 200 0.223
Zebrafish
regulation of hydrolase activity GO:0051336 246 0.222
stress activated protein kinase signaling cascade GO:0031098 81 0.218
nucleotide catabolic process GO:0009166 217 0.218
gtp catabolic process GO:0006184 143 0.213
nucleoside triphosphate catabolic process GO:0009143 205 0.211
ribose phosphate metabolic process GO:0019693 291 0.209
regulation of mapk cascade GO:0043408 248 0.206
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.201
cytokine production GO:0001816 319 0.201
purine nucleoside metabolic process GO:0042278 241 0.200
regulation of innate immune response GO:0045088 91 0.199
trna wobble base modification GO:0002097 2 0.193
regulation of cellular amino acid metabolic process GO:0006521 5 0.192
t cell activation GO:0042110 289 0.187
regulation of protein kinase activity GO:0045859 232 0.187
Human
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.185
nucleoside metabolic process GO:0009116 246 0.185
regulation of map kinase activity GO:0043405 120 0.184
purine ribonucleotide catabolic process GO:0009154 208 0.183
purine ribonucleoside metabolic process GO:0046128 241 0.183
establishment of synaptic vesicle localization GO:0097480 57 0.182
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.179
regulation of nucleotide metabolic process GO:0006140 169 0.178
neural tube development GO:0021915 160 0.176
organophosphate catabolic process GO:0046434 232 0.170
carbohydrate derivative catabolic process GO:1901136 231 0.169
chromosome segregation GO:0007059 48 0.166
activation of jnkk activity GO:0007256 3 0.162
purine nucleoside triphosphate catabolic process GO:0009146 203 0.159
regulation of cellular amine metabolic process GO:0033238 20 0.157
regulation of t cell activation GO:0050863 170 0.156
compound eye development GO:0048749 1 0.155
glycosyl compound catabolic process GO:1901658 206 0.153
regulation of cellular response to stress GO:0080135 159 0.149
ribonucleoside triphosphate metabolic process GO:0009199 220 0.148
synaptic vesicle transport GO:0048489 57 0.148
synaptic vesicle localization GO:0097479 59 0.144
positive regulation of kinase activity GO:0033674 155 0.140
Human
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.139
apical constriction GO:0003383 4 0.138
mapk cascade GO:0000165 281 0.138
nucleobase containing small molecule metabolic process GO:0055086 352 0.137
regulation of jnk cascade GO:0046328 62 0.135
regulation of nik nf kappab signaling GO:1901222 10 0.135
stem cell differentiation GO:0048863 268 0.133
negative regulation of mapk cascade GO:0043409 65 0.130
homeostasis of number of cells GO:0048872 210 0.127
macromolecule methylation GO:0043414 120 0.127
stress activated mapk cascade GO:0051403 80 0.127
purine containing compound metabolic process GO:0072521 311 0.127
regulation of nucleoside metabolic process GO:0009118 130 0.126
regulation of cytokine production GO:0001817 266 0.124
purine nucleotide metabolic process GO:0006163 302 0.122
small gtpase mediated signal transduction GO:0007264 97 0.122
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.122
regulation of cell activation GO:0050865 289 0.121
embryonic epithelial tube formation GO:0001838 130 0.120
purine nucleotide catabolic process GO:0006195 211 0.120
organonitrogen compound catabolic process GO:1901565 264 0.119
protein acylation GO:0043543 64 0.119
glycosyl compound metabolic process GO:1901657 246 0.118
guanosine containing compound metabolic process GO:1901068 144 0.116
negative regulation of cellular amine metabolic process GO:0033239 1 0.116
ribonucleotide catabolic process GO:0009261 208 0.115
regulation of protein serine threonine kinase activity GO:0071900 157 0.115
leukocyte proliferation GO:0070661 172 0.114
regulation of kinase activity GO:0043549 249 0.114
Human
immune effector process GO:0002252 321 0.113
meiosis i GO:0007127 60 0.113
mitotic cell cycle GO:0000278 195 0.108
erythrocyte differentiation GO:0030218 88 0.107
epithelial tube formation GO:0072175 130 0.105
amine metabolic process GO:0009308 45 0.105
meiotic cell cycle process GO:1903046 77 0.105
cellular response to growth factor stimulus GO:0071363 197 0.104
positive regulation of cellular catabolic process GO:0031331 148 0.102
regulation of proteolysis GO:0030162 164 0.101
ribonucleotide metabolic process GO:0009259 291 0.100
purine ribonucleotide metabolic process GO:0009150 290 0.100
neural tube closure GO:0001843 90 0.099
cellular response to dna damage stimulus GO:0006974 207 0.098
purine containing compound catabolic process GO:0072523 213 0.098
regulation of nucleotide catabolic process GO:0030811 122 0.098
gland development GO:0048732 330 0.097
negative regulation of phosphorylation GO:0042326 166 0.097
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.096
meiotic cell cycle GO:0051321 122 0.096
apoptotic signaling pathway GO:0097190 306 0.093
positive regulation of protein kinase activity GO:0045860 144 0.093
Human
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.092
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.091
positive regulation of innate immune response GO:0045089 80 0.091
jnk cascade GO:0007254 72 0.090
regulation of response to wounding GO:1903034 189 0.089
response to transforming growth factor beta GO:0071559 88 0.089
rab protein signal transduction GO:0032482 1 0.088
tube formation GO:0035148 140 0.087
immune response regulating signaling pathway GO:0002764 125 0.086
regulation of lymphocyte activation GO:0051249 240 0.085
regulation of gtp catabolic process GO:0033124 113 0.085
regulation of cellular ketone metabolic process GO:0010565 66 0.084
aromatic compound catabolic process GO:0019439 286 0.083
negative regulation of osteoblast proliferation GO:0033689 4 0.079
response to molecule of bacterial origin GO:0002237 143 0.079
positive regulation of leukocyte differentiation GO:1902107 86 0.078
skeletal system development GO:0001501 356 0.078
myeloid cell differentiation GO:0030099 233 0.077
ribonucleoside catabolic process GO:0042454 206 0.076
protein polyubiquitination GO:0000209 33 0.076
spermatogenesis GO:0007283 284 0.076
establishment of vesicle localization GO:0051650 81 0.076
positive regulation of cytokine production GO:0001819 174 0.075
regulation of leukocyte proliferation GO:0070663 121 0.074
cellular response to hormone stimulus GO:0032870 150 0.074
cellular nitrogen compound catabolic process GO:0044270 280 0.074
regulation of secretion GO:0051046 274 0.073
nucleoside catabolic process GO:0009164 206 0.072
actin cytoskeleton organization GO:0030036 220 0.071
neural tube formation GO:0001841 108 0.071
morphogenesis of embryonic epithelium GO:0016331 159 0.070
regulation of cellular response to growth factor stimulus GO:0090287 82 0.070
positive regulation of transferase activity GO:0051347 167 0.070
Human
regulation of mitotic cell cycle GO:0007346 126 0.069
leukocyte mediated immunity GO:0002443 174 0.069
guanosine containing compound catabolic process GO:1901069 144 0.068
respiratory tube development GO:0030323 167 0.067
negative regulation of protein modification process GO:0031400 163 0.066
regulation of neurotransmitter transport GO:0051588 35 0.066
leukocyte differentiation GO:0002521 342 0.066
rhythmic process GO:0048511 174 0.064
organic cyclic compound catabolic process GO:1901361 295 0.064
cell adhesion GO:0007155 329 0.064
regulation of cell migration GO:0030334 219 0.063
regulation of lymphocyte proliferation GO:0050670 117 0.063
lymphocyte proliferation GO:0046651 164 0.063
ribonucleoside metabolic process GO:0009119 245 0.062
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.062
regulation of ossification GO:0030278 112 0.062
b cell homeostasis GO:0001782 34 0.062
tube closure GO:0060606 91 0.060
cellular ketone metabolic process GO:0042180 84 0.060
lung development GO:0030324 164 0.060
interleukin 6 production GO:0032635 58 0.060
negative regulation of cell cycle GO:0045786 123 0.060
blood circulation GO:0008015 195 0.059
cellular amine metabolic process GO:0044106 44 0.059
cell fate commitment GO:0045165 210 0.058
activation of immune response GO:0002253 138 0.058
immune response activating signal transduction GO:0002757 116 0.057
regulation of cellular catabolic process GO:0031329 242 0.057
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.056
embryonic skeletal system development GO:0048706 120 0.054
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.053
regulation of ras protein signal transduction GO:0046578 114 0.052
nucleotide metabolic process GO:0009117 332 0.052
cellular response to insulin stimulus GO:0032869 78 0.052
lipid storage GO:0019915 36 0.051
mitotic cell cycle process GO:1903047 159 0.051
digestive tract morphogenesis GO:0048546 147 0.050
Zebrafish
muscle cell differentiation GO:0042692 261 0.050
male gamete generation GO:0048232 285 0.050
stem cell development GO:0048864 219 0.048
protein modification by small protein conjugation GO:0032446 187 0.048
regulation of response to dna damage stimulus GO:2001020 34 0.047
regulation of inflammatory response GO:0050727 147 0.047
primary neural tube formation GO:0014020 95 0.047
b cell proliferation GO:0042100 53 0.047
blood vessel morphogenesis GO:0048514 285 0.047
lymphocyte differentiation GO:0030098 242 0.046
peptidyl lysine modification GO:0018205 77 0.046
muscle cell fate specification GO:0042694 1 0.046
positive regulation of proteolysis GO:0045862 85 0.046
digestive tract development GO:0048565 190 0.046
Zebrafish
chromatin silencing GO:0006342 15 0.046
circadian rhythm GO:0007623 114 0.045
positive regulation of ras gtpase activity GO:0032320 65 0.045
ameboidal type cell migration GO:0001667 128 0.045
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.044
organelle localization GO:0051640 179 0.044
connective tissue development GO:0061448 179 0.044
macromolecule glycosylation GO:0043413 55 0.044
dna metabolic process GO:0006259 303 0.044
epithelial tube morphogenesis GO:0060562 303 0.043
negative regulation of necroptotic process GO:0060546 9 0.043
regulation of establishment of protein localization GO:0070201 181 0.043
body morphogenesis GO:0010171 45 0.043
regulation of cell cycle process GO:0010564 160 0.043
liver development GO:0001889 66 0.043
internal peptidyl lysine acetylation GO:0018393 42 0.043
regulation of stress activated mapk cascade GO:0032872 69 0.043
positive regulation of map kinase activity GO:0043406 84 0.043
regulation of nucleocytoplasmic transport GO:0046822 73 0.043
carbohydrate derivative biosynthetic process GO:1901137 183 0.042
respiratory system development GO:0060541 190 0.042
fat cell differentiation GO:0045444 160 0.042
kidney mesenchyme morphogenesis GO:0072131 4 0.042
heterocycle catabolic process GO:0046700 280 0.042
regulation of purine nucleotide catabolic process GO:0033121 122 0.041
activation of mapkk activity GO:0000186 15 0.041
single organism cell adhesion GO:0098602 156 0.041
t cell receptor signaling pathway GO:0050852 46 0.041
positive regulation of jnk cascade GO:0046330 46 0.041
regulation of ras gtpase activity GO:0032318 88 0.041
negative regulation of immune system process GO:0002683 209 0.040
response to organic cyclic compound GO:0014070 198 0.040
negative regulation of phosphate metabolic process GO:0045936 184 0.040
exocytosis GO:0006887 121 0.040
t cell differentiation GO:0030217 174 0.040
regulation of synaptic vesicle transport GO:1902803 13 0.040
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.039
regulation of transforming growth factor beta2 production GO:0032909 2 0.039
endocytosis GO:0006897 168 0.039
microtubule based process GO:0007017 236 0.039
innate immune response GO:0045087 157 0.039
protein autophosphorylation GO:0046777 61 0.038
negative regulation of neurotransmitter secretion GO:0046929 5 0.038
peptidyl tyrosine modification GO:0018212 145 0.038
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.038
response to growth factor GO:0070848 198 0.038
blastocyst development GO:0001824 80 0.038
asymmetric stem cell division GO:0098722 3 0.038
negative regulation of cellular protein metabolic process GO:0032269 247 0.037
regulation of exocytosis GO:0017157 61 0.037
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.037
regulation of vesicle mediated transport GO:0060627 139 0.037
negative regulation of neuron death GO:1901215 98 0.037
regulation of leukocyte differentiation GO:1902105 159 0.036
mesenchyme development GO:0060485 152 0.036
chondrocyte differentiation GO:0002062 72 0.036
organelle fission GO:0048285 170 0.036
positive regulation of gtpase activity GO:0043547 85 0.036
negative regulation of ras protein signal transduction GO:0046580 18 0.035
endomembrane system organization GO:0010256 147 0.035
canonical wnt signaling pathway GO:0060070 130 0.035
positive regulation of gtp catabolic process GO:0033126 85 0.035
hepaticobiliary system development GO:0061008 67 0.035
protein glycosylation GO:0006486 55 0.035
oocyte construction GO:0007308 2 0.035
nephrogenic mesenchyme development GO:0072076 3 0.034
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.034
cellular response to organic cyclic compound GO:0071407 87 0.034
rap protein signal transduction GO:0032486 3 0.034
activation of mapk activity GO:0000187 59 0.034
mesodermal cell migration GO:0008078 4 0.034
chemotaxis GO:0006935 247 0.034
regulation of chromatin organization GO:1902275 57 0.033
protein ubiquitination GO:0016567 171 0.033
cerebellum development GO:0021549 77 0.033
positive regulation of nucleoside metabolic process GO:0045979 91 0.033
antigen receptor mediated signaling pathway GO:0050851 64 0.033
negative regulation of protein phosphorylation GO:0001933 126 0.033
germ line stem cell division GO:0042078 2 0.032
endodermal cell fate specification GO:0001714 4 0.032
histone h3 acetylation GO:0043966 14 0.032
urogenital system development GO:0001655 261 0.032
regulation of interleukin 6 production GO:0032675 55 0.032
regulation of erk1 and erk2 cascade GO:0070372 71 0.032
negative regulation of leukocyte proliferation GO:0070664 46 0.032
stem cell fate specification GO:0048866 3 0.032
positive regulation of defense response GO:0031349 124 0.031
cellular response to molecule of bacterial origin GO:0071219 83 0.031
cellular protein catabolic process GO:0044257 155 0.031
glycoprotein metabolic process GO:0009100 116 0.031
genetic imprinting GO:0071514 27 0.030
regulation of protein localization GO:0032880 231 0.030
regulation of clathrin mediated endocytosis GO:2000369 4 0.030
negative regulation of lymphocyte activation GO:0051250 91 0.030
dna methylation GO:0006306 43 0.029
non canonical wnt signaling pathway GO:0035567 33 0.029
stem cell maintenance GO:0019827 130 0.029
regulation of histone modification GO:0031056 56 0.029
lymphocyte homeostasis GO:0002260 64 0.029
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.028
peptidyl lysine acetylation GO:0018394 45 0.028
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
positive regulation of hydrolase activity GO:0051345 148 0.028
cellular response to abiotic stimulus GO:0071214 56 0.028
regulation of t cell proliferation GO:0042129 92 0.028
negative regulation of t cell proliferation GO:0042130 38 0.028
segmentation GO:0035282 93 0.028
establishment or maintenance of cell polarity GO:0007163 86 0.028
peptidyl threonine phosphorylation GO:0018107 31 0.027
protein import into nucleus GO:0006606 95 0.027
regulation of cell motility GO:2000145 236 0.027
neuronal action potential GO:0019228 54 0.027
negative regulation of cell motility GO:2000146 61 0.027
negative regulation of lymphocyte proliferation GO:0050672 45 0.027
cellular response to interleukin 15 GO:0071350 2 0.026
response to lipopolysaccharide GO:0032496 128 0.026
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 3 0.026
molting cycle GO:0042303 90 0.026
metencephalon development GO:0022037 89 0.026
regulation of organelle organization GO:0033043 289 0.026
regulation of autophagy GO:0010506 30 0.026
regulation of necrotic cell death GO:0010939 13 0.026
positive regulation of rab gtpase activity GO:0032851 7 0.026
positive regulation of nucleotide metabolic process GO:0045981 114 0.026
positive regulation of cell adhesion GO:0045785 80 0.025
oocyte anterior posterior axis specification GO:0007314 2 0.025
carbohydrate metabolic process GO:0005975 230 0.025
male meiosis GO:0007140 37 0.025
skeletal system morphogenesis GO:0048705 203 0.025
positive regulation of t cell cytokine production GO:0002726 5 0.025
cellular response to organonitrogen compound GO:0071417 145 0.025
meiotic nuclear division GO:0007126 115 0.025
b cell activation GO:0042113 161 0.024
heart morphogenesis GO:0003007 178 0.024
cell substrate adhesion GO:0031589 130 0.024
inflammatory response GO:0006954 244 0.024
neurofilament cytoskeleton organization GO:0060052 10 0.024
hindbrain development GO:0030902 128 0.024
adaptive immune response GO:0002250 155 0.024
regulation of ripoptosome assembly involved in necroptotic process GO:1902442 3 0.024
peptidyl tyrosine phosphorylation GO:0018108 143 0.024
embryonic body morphogenesis GO:0010172 10 0.024
regulation of proteasomal protein catabolic process GO:0061136 46 0.024
neuron death GO:0070997 154 0.023
regulation of mitotic cell cycle phase transition GO:1901990 73 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.023
gliogenesis GO:0042063 141 0.023
regulation of cytokine production involved in immune response GO:0002718 26 0.023
peptidyl threonine modification GO:0018210 31 0.023
organ growth GO:0035265 117 0.023
cell proliferation involved in heart valve morphogenesis GO:0003249 1 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.022
modification dependent protein catabolic process GO:0019941 133 0.022
asymmetric neuroblast division GO:0055059 1 0.022
regulation of protein deacetylation GO:0090311 17 0.022
negative regulation of osteoblast differentiation GO:0045668 30 0.022
positive regulation of cellular protein catabolic process GO:1903364 34 0.022
regulation of cellular component size GO:0032535 121 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.022
glutamate receptor signaling pathway GO:0007215 35 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
regulation of endocytosis GO:0030100 69 0.022
multicellular organismal signaling GO:0035637 91 0.022
negative regulation of neurotransmitter transport GO:0051589 7 0.022
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.022
response to peptide hormone GO:0043434 127 0.022
nuclear division GO:0000280 158 0.022
neural precursor cell proliferation GO:0061351 121 0.022
axonogenesis GO:0007409 274 0.021
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.021
single organismal cell cell adhesion GO:0016337 131 0.021
retina development in camera type eye GO:0060041 119 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
gastrulation GO:0007369 116 0.021
Zebrafish
mitotic cytokinesis GO:0000281 4 0.021
actomyosin structure organization GO:0031032 56 0.021
regulation of neurotransmitter secretion GO:0046928 29 0.021
kidney development GO:0001822 213 0.021
somitogenesis GO:0001756 69 0.021
vesicle localization GO:0051648 86 0.021
regulation of cell adhesion GO:0030155 154 0.021
lung epithelium development GO:0060428 37 0.021
response to alcohol GO:0097305 48 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
regulation of chromatin silencing GO:0031935 2 0.021
positive regulation of t cell mediated immunity GO:0002711 24 0.021
regulation of secretion by cell GO:1903530 249 0.021
ossification GO:0001503 216 0.020
peptidyl serine modification GO:0018209 83 0.020
cell migration involved in gastrulation GO:0042074 13 0.020
epithelial cell migration GO:0010631 63 0.020
intermediate filament cytoskeleton organization GO:0045104 26 0.020
smad protein complex assembly GO:0007183 1 0.020
protein alkylation GO:0008213 81 0.020
dna alkylation GO:0006305 43 0.020
regulation of protein complex assembly GO:0043254 83 0.020
smoothened signaling pathway GO:0007224 105 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
rho protein signal transduction GO:0007266 32 0.020
cellular response to peptide GO:1901653 92 0.020
positive regulation of nervous system development GO:0051962 221 0.020
regulation of osteoblast differentiation GO:0045667 67 0.020
regulation of peptidyl threonine phosphorylation GO:0010799 12 0.019
sensory organ morphogenesis GO:0090596 242 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
regulation of cellular protein catabolic process GO:1903362 61 0.019
maternal determination of anterior posterior axis embryo GO:0008358 2 0.019
regulation of actin nucleation GO:0051125 4 0.019
regulation of cell cycle GO:0051726 281 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.019
negative regulation of molecular function GO:0044092 258 0.019
cellular response to external stimulus GO:0071496 88 0.019
t cell mediated immunity GO:0002456 50 0.019
erk1 and erk2 cascade GO:0070371 77 0.019
regulation of system process GO:0044057 200 0.019
negative regulation of t helper 1 cell differentiation GO:0045626 3 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.019
sensory perception GO:0007600 245 0.019
lipid localization GO:0010876 126 0.019
regulation of fat cell differentiation GO:0045598 81 0.019
positive regulation of multi organism process GO:0043902 26 0.019
muscle tissue development GO:0060537 308 0.019
respiratory gaseous exchange GO:0007585 43 0.018
regulation of cell size GO:0008361 72 0.018
learning or memory GO:0007611 148 0.018
positive regulation of ossification GO:0045778 47 0.018
response to insulin GO:0032868 100 0.018
regulation of chromatin modification GO:1903308 57 0.018
negative regulation of defense response GO:0031348 77 0.018
negative regulation of cellular catabolic process GO:0031330 47 0.018
face development GO:0060324 38 0.018
cellular response to oxidative stress GO:0034599 76 0.018
dna damage checkpoint GO:0000077 26 0.018
regulation of t cell differentiation GO:0045580 83 0.018
cytokine production involved in immune response GO:0002367 34 0.018
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.018
axon guidance GO:0007411 141 0.018
renal system development GO:0072001 225 0.018
heart contraction GO:0060047 93 0.018
positive regulation of nik nf kappab signaling GO:1901224 7 0.018
camera type eye development GO:0043010 266 0.017
regulation of synaptic vesicle exocytosis GO:2000300 11 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.017
bone development GO:0060348 120 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
regulation of leukocyte mediated immunity GO:0002703 104 0.017
regulation of adaptive immune response GO:0002819 90 0.017
regulation of body fluid levels GO:0050878 162 0.017
cognition GO:0050890 149 0.017
cellular response to biotic stimulus GO:0071216 92 0.017
intracellular receptor signaling pathway GO:0030522 74 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
negative regulation of cell migration GO:0030336 59 0.017
positive regulation of myeloid cell differentiation GO:0045639 43 0.017
regulation of wnt signaling pathway GO:0030111 123 0.017
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.017
positive regulation of smad protein import into nucleus GO:0060391 2 0.017
dna modification GO:0006304 50 0.017
positive regulation of cell cycle phase transition GO:1901989 17 0.016
golgi to endosome transport GO:0006895 3 0.016
carbohydrate homeostasis GO:0033500 128 0.016
positive regulation of secretion by cell GO:1903532 114 0.016
cellular response to lipid GO:0071396 145 0.016
intermediate filament based process GO:0045103 27 0.016
negative regulation of mitotic cell cycle GO:0045930 58 0.016
dephosphorylation GO:0016311 129 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
cell fate specification GO:0001708 72 0.016
epithelial to mesenchymal transition GO:0001837 47 0.016
amide transport GO:0042886 138 0.016
antibacterial peptide biosynthetic process GO:0002780 2 0.016
pole plasm assembly GO:0007315 2 0.016
uterus morphogenesis GO:0061038 2 0.016
response to peptide GO:1901652 136 0.016
response to oxidative stress GO:0006979 123 0.016
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.016
memory GO:0007613 58 0.016
defense response to other organism GO:0098542 197 0.016

Tab2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.173
cancer DOID:162 0 0.074
organ system cancer DOID:0050686 0 0.062
gastrointestinal system cancer DOID:3119 0 0.029
colorectal cancer DOID:9256 0 0.029
intestinal cancer DOID:10155 0 0.029
colon cancer DOID:219 0 0.029
large intestine cancer DOID:5672 0 0.029
muscular disease DOID:0080000 0 0.016
muscle tissue disease DOID:66 0 0.016
myopathy DOID:423 0 0.016
musculoskeletal system disease DOID:17 0 0.016
disease of anatomical entity DOID:7 0 0.016