Mus musculus

118 known processes

Tab1

TGF-beta activated kinase 1/MAP3K7 binding protein 1

(Aliases: Map3k7ip1,2310012M03Rik)

Tab1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
activation of mapkk activity GO:0000186 15 0.323
positive regulation of protein phosphorylation GO:0001934 242 0.269
regulation of protein kinase activity GO:0045859 232 0.268
cellular protein catabolic process GO:0044257 155 0.254
regulation of stress activated mapk cascade GO:0032872 69 0.235
regulation of protein serine threonine kinase activity GO:0071900 157 0.224
modification dependent protein catabolic process GO:0019941 133 0.222
activation of nf kappab inducing kinase activity GO:0007250 4 0.222
regulation of jun kinase activity GO:0043506 40 0.219
regulation of terminal button organization GO:2000331 1 0.206
positive regulation of protein kinase activity GO:0045860 144 0.196
regulation of transferase activity GO:0051338 263 0.193
positive regulation of kinase activity GO:0033674 155 0.185
axon transport of mitochondrion GO:0019896 2 0.178
activation of jnkk activity GO:0007256 3 0.174
peptidyl amino acid modification GO:0018193 336 0.172
protein modification by small protein conjugation GO:0032446 187 0.169
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.169
protein modification by small protein conjugation or removal GO:0070647 207 0.157
modification dependent macromolecule catabolic process GO:0043632 133 0.154
regulation of jnk cascade GO:0046328 62 0.138
positive regulation of apoptotic process GO:0043065 217 0.136
jnk cascade GO:0007254 72 0.130
negative regulation of jun kinase activity GO:0043508 9 0.127
positive regulation of mapk cascade GO:0043410 170 0.124
ubiquitin dependent protein catabolic process GO:0006511 129 0.122
stress activated mapk cascade GO:0051403 80 0.110
positive regulation of transferase activity GO:0051347 167 0.108
regulation of mapk cascade GO:0043408 248 0.104
stress activated protein kinase signaling cascade GO:0031098 81 0.099
protein catabolic process GO:0030163 221 0.098
cellular amino acid metabolic process GO:0006520 103 0.093
membrane depolarization GO:0051899 64 0.092
apoptotic mitochondrial changes GO:0008637 48 0.090
regulation of cellular response to stress GO:0080135 159 0.084
terminal button organization GO:0072553 3 0.083
regulation of map kinase activity GO:0043405 120 0.080
regulation of cytoskeleton organization GO:0051493 122 0.077
negative regulation of ripoptosome assembly involved in necroptotic process GO:1902443 3 0.075
intrinsic apoptotic signaling pathway GO:0097193 132 0.073
cellular ketone metabolic process GO:0042180 84 0.071
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.070
mapk cascade GO:0000165 281 0.070
peptidyl serine modification GO:0018209 83 0.070
negative regulation of cellular component organization GO:0051129 194 0.069
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.069
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.067
regulation of cellular amino acid metabolic process GO:0006521 5 0.066
histone modification GO:0016570 159 0.066
regulation of apoptotic signaling pathway GO:2001233 197 0.066
regulation of organelle organization GO:0033043 289 0.064
regulation of cellular catabolic process GO:0031329 242 0.063
viral gene expression GO:0019080 3 0.061
mitochondrion organization GO:0007005 134 0.061
cellular response to abiotic stimulus GO:0071214 56 0.061
negative regulation of protein modification process GO:0031400 163 0.060
actin cytoskeleton organization GO:0030036 220 0.058
protein oligomerization GO:0051259 67 0.058
regulation of kinase activity GO:0043549 249 0.058
regulation of postsynaptic membrane potential GO:0060078 48 0.057
response to growth factor GO:0070848 198 0.056
cellular response to growth factor stimulus GO:0071363 197 0.055
regulation of secretion GO:0051046 274 0.054
transmembrane transport GO:0055085 412 0.053
positive regulation of jun kinase activity GO:0043507 30 0.053
organonitrogen compound biosynthetic process GO:1901566 192 0.053
apoptotic signaling pathway GO:0097190 306 0.053
nucleotide metabolic process GO:0009117 332 0.052
peptide transport GO:0015833 133 0.052
macromolecule catabolic process GO:0009057 281 0.052
regulation of actin filament based process GO:0032970 99 0.051
peptidyl serine phosphorylation GO:0018105 74 0.051
negative regulation of molecular function GO:0044092 258 0.047
protein autophosphorylation GO:0046777 61 0.047
regulation of multi organism process GO:0043900 111 0.046
regulation of actin cytoskeleton organization GO:0032956 84 0.046
ion transmembrane transport GO:0034220 361 0.046
response to osmotic stress GO:0006970 21 0.046
regulation of membrane potential GO:0042391 192 0.044
regulation of cellular component biogenesis GO:0044087 181 0.044
microtubule based process GO:0007017 236 0.044
response to transforming growth factor beta GO:0071559 88 0.043
activation of mapk activity GO:0000187 59 0.042
negative regulation of necroptotic process GO:0060546 9 0.042
negative regulation of phosphorylation GO:0042326 166 0.042
negative regulation of apoptotic signaling pathway GO:2001234 104 0.042
sterol metabolic process GO:0016125 58 0.041
response to organic cyclic compound GO:0014070 198 0.041
regulation of glutamate receptor signaling pathway GO:1900449 16 0.041
synaptic transmission GO:0007268 329 0.041
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.041
positive regulation of cell death GO:0010942 224 0.039
synaptic vesicle transport GO:0048489 57 0.039
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.039
regulation of cell migration GO:0030334 219 0.038
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.038
antibacterial peptide production GO:0002778 2 0.038
peptide secretion GO:0002790 114 0.037
regulation of viral transcription GO:0046782 3 0.036
positive regulation of map kinase activity GO:0043406 84 0.036
negative regulation of necrotic cell death GO:0060547 11 0.036
viral process GO:0016032 41 0.036
protein ubiquitination GO:0016567 171 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
protein polyubiquitination GO:0000209 33 0.035
negative regulation of cytoskeleton organization GO:0051494 36 0.035
cytoplasmic transport GO:0016482 234 0.035
protein import into nucleus GO:0006606 95 0.034
heterocycle catabolic process GO:0046700 280 0.034
axonogenesis GO:0007409 274 0.034
cholesterol metabolic process GO:0008203 56 0.034
amine metabolic process GO:0009308 45 0.034
positive regulation of programmed cell death GO:0043068 218 0.034
positive regulation of proteolysis GO:0045862 85 0.034
digestive tract morphogenesis GO:0048546 147 0.034
Worm
viral transcription GO:0019083 3 0.033
cellular homeostasis GO:0019725 240 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.033
immune effector process GO:0002252 321 0.033
negative regulation of phosphorus metabolic process GO:0010563 184 0.033
chromatin organization GO:0006325 206 0.033
axon cargo transport GO:0008088 33 0.033
vesicle localization GO:0051648 86 0.032
tube formation GO:0035148 140 0.032
response to amino acid GO:0043200 37 0.031
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.031
positive regulation of jnk cascade GO:0046330 46 0.031
aromatic compound catabolic process GO:0019439 286 0.031
actin polymerization or depolymerization GO:0008154 54 0.031
nitrogen compound transport GO:0071705 271 0.031
regulation of proteolysis GO:0030162 164 0.031
multicellular organismal homeostasis GO:0048871 164 0.030
antimicrobial peptide biosynthetic process GO:0002777 2 0.030
protein import GO:0017038 101 0.030
muscle cell differentiation GO:0042692 261 0.029
regulation of transmembrane transport GO:0034762 128 0.029
protein polymerization GO:0051258 57 0.029
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.029
antimicrobial peptide production GO:0002775 2 0.029
organelle localization GO:0051640 179 0.029
establishment of organelle localization GO:0051656 122 0.029
compound eye development GO:0048749 1 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.028
nuclear transport GO:0051169 139 0.028
regulation of phospholipase a2 activity GO:0032429 3 0.028
interspecies interaction between organisms GO:0044419 83 0.028
camera type eye development GO:0043010 266 0.028
positive regulation of cellular catabolic process GO:0031331 148 0.028
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.028
reactive oxygen species metabolic process GO:0072593 84 0.028
multicellular organismal response to stress GO:0033555 62 0.027
regulation of ion transmembrane transporter activity GO:0032412 54 0.027
regulation of secretion by cell GO:1903530 249 0.027
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.027
actin filament organization GO:0007015 113 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
cellular response to carbohydrate stimulus GO:0071322 50 0.027
cellular chemical homeostasis GO:0055082 215 0.027
positive regulation of stress activated mapk cascade GO:0032874 48 0.026
learning GO:0007612 98 0.026
antibacterial peptide biosynthetic process GO:0002780 2 0.026
gastrulation GO:0007369 116 0.026
Worm
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
organic cyclic compound catabolic process GO:1901361 295 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
intracellular protein transport GO:0006886 204 0.025
actin filament bundle assembly GO:0051017 40 0.025
negative regulation of organelle organization GO:0010639 90 0.025
dna metabolic process GO:0006259 303 0.025
peptidyl tyrosine phosphorylation GO:0018108 143 0.025
blood vessel morphogenesis GO:0048514 285 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.024
negative regulation of mapk cascade GO:0043409 65 0.024
positive regulation of homeostatic process GO:0032846 64 0.024
regulation of plasma lipoprotein particle levels GO:0097006 23 0.023
cytokine production GO:0001816 319 0.023
inflammatory response GO:0006954 244 0.023
neural tube formation GO:0001841 108 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.023
positive regulation of cellular component biogenesis GO:0044089 94 0.023
microtubule based movement GO:0007018 84 0.023
regulation of hormone levels GO:0010817 211 0.023
positive regulation of organelle organization GO:0010638 128 0.022
protein targeting GO:0006605 143 0.022
wnt signaling pathway GO:0016055 188 0.022
regulation of cellular component size GO:0032535 121 0.022
anatomical structure homeostasis GO:0060249 145 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
fear response GO:0042596 33 0.022
actin filament polymerization GO:0030041 44 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
carbohydrate homeostasis GO:0033500 128 0.022
epithelial tube formation GO:0072175 130 0.022
negative regulation of map kinase activity GO:0043407 34 0.022
regulation of anatomical structure size GO:0090066 178 0.022
glucose homeostasis GO:0042593 128 0.022
viral life cycle GO:0019058 36 0.022
regulation of actin filament polymerization GO:0030833 38 0.022
regulation of defense response to bacterium GO:1900424 3 0.021
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.021
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
regulation of protein complex assembly GO:0043254 83 0.021
digestive system development GO:0055123 200 0.021
Worm
regulation of hydrolase activity GO:0051336 246 0.021
regulation of actin filament bundle assembly GO:0032231 18 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
regulation of binding GO:0051098 111 0.021
positive regulation of protein modification process GO:0031401 299 0.021
purine containing compound catabolic process GO:0072523 213 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
activation of jun kinase activity GO:0007257 15 0.021
tissue homeostasis GO:0001894 115 0.021
nucleoside metabolic process GO:0009116 246 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
cellular response to external stimulus GO:0071496 88 0.020
embryonic epithelial tube formation GO:0001838 130 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
negative regulation of transferase activity GO:0051348 85 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
learning or memory GO:0007611 148 0.020
hormone secretion GO:0046879 128 0.020
microtubule based transport GO:0010970 50 0.020
alcohol metabolic process GO:0006066 116 0.020
purine containing compound metabolic process GO:0072521 311 0.020
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.020
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.020
muscle tissue development GO:0060537 308 0.020
neural tube development GO:0021915 160 0.020
telencephalon development GO:0021537 186 0.020
cardiac muscle tissue development GO:0048738 130 0.020
ossification GO:0001503 216 0.020
skeletal system development GO:0001501 356 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
synapse organization GO:0050808 125 0.019
skin development GO:0043588 220 0.019
peptide hormone secretion GO:0030072 109 0.019
organophosphate biosynthetic process GO:0090407 122 0.019
behavioral fear response GO:0001662 28 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
regulation of transporter activity GO:0032409 57 0.019
regulation of presynaptic membrane organization GO:1901629 3 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
cardiac septum development GO:0003279 59 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
Worm
angiogenesis GO:0001525 201 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
amide transport GO:0042886 138 0.019
positive regulation of secretion GO:0051047 130 0.019
lipid transport GO:0006869 98 0.019
cellular amine metabolic process GO:0044106 44 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
synaptic vesicle localization GO:0097479 59 0.018
respiratory system development GO:0060541 190 0.018
meiotic cell cycle GO:0051321 122 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
insulin secretion GO:0030073 89 0.018
cellular protein complex assembly GO:0043623 116 0.018
regulation of defense response GO:0031347 233 0.018
response to organonitrogen compound GO:0010243 246 0.018
appendage morphogenesis GO:0035107 149 0.018
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.018
primary neural tube formation GO:0014020 95 0.018
intracellular cholesterol transport GO:0032367 3 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
trunk segmentation GO:0035290 4 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.017
regulation of actin filament length GO:0030832 45 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
epithelial cell development GO:0002064 159 0.017
proteasomal protein catabolic process GO:0010498 98 0.017
positive regulation of antimicrobial peptide production GO:0002225 1 0.017
positive regulation of protein complex assembly GO:0031334 45 0.017
metencephalon development GO:0022037 89 0.017
protein palmitoylation GO:0018345 14 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
cellular response to monosaccharide stimulus GO:0071326 47 0.017
stem cell differentiation GO:0048863 268 0.017
cognition GO:0050890 149 0.017
tissue remodeling GO:0048771 102 0.017
protein maturation GO:0051604 176 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
formation of radial glial scaffolds GO:0021943 4 0.017
regulation of antimicrobial humoral response GO:0002759 3 0.017
leukocyte mediated immunity GO:0002443 174 0.017
regulation of peptide secretion GO:0002791 77 0.017
regulation of cell cycle process GO:0010564 160 0.017
establishment of vesicle localization GO:0051650 81 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.017
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
behavioral defense response GO:0002209 28 0.016
connective tissue development GO:0061448 179 0.016
myeloid cell differentiation GO:0030099 233 0.016
cytoskeleton dependent intracellular transport GO:0030705 50 0.016
gland development GO:0048732 330 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
intracellular lipid transport GO:0032365 3 0.016
cellular response to lipid GO:0071396 145 0.016
regulation of peptide transport GO:0090087 91 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
cell division GO:0051301 120 0.016
stem cell maintenance GO:0019827 130 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
cellular response to lipopolysaccharide GO:0071222 77 0.016
sulfur compound metabolic process GO:0006790 100 0.016
pallium development GO:0021543 120 0.016
cholesterol transport GO:0030301 38 0.016
membrane organization GO:0061024 245 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
regulation of cytokine production GO:0001817 266 0.016
sensory perception GO:0007600 245 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
lipid localization GO:0010876 126 0.016
epidermis development GO:0008544 187 0.016
negative regulation of sterol transport GO:0032372 4 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
anterograde synaptic vesicle transport GO:0048490 15 0.015
positive regulation of multi organism process GO:0043902 26 0.015
regulation of protein catabolic process GO:0042176 108 0.015
homeostasis of number of cells GO:0048872 210 0.015
innate immune response GO:0045087 157 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
wound healing GO:0042060 157 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
cell migration involved in gastrulation GO:0042074 13 0.015
cellular response to hexose stimulus GO:0071331 47 0.015
epithelial cell proliferation GO:0050673 174 0.015
regulation of cell motility GO:2000145 236 0.015
positive regulation of nervous system development GO:0051962 221 0.015
leukocyte differentiation GO:0002521 342 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
cartilage development GO:0051216 140 0.015
mating GO:0007618 27 0.015
response to lipopolysaccharide GO:0032496 128 0.015
regulation of antibacterial peptide production GO:0002786 1 0.015
striated muscle tissue development GO:0014706 293 0.015
regulation of ossification GO:0030278 112 0.015
plasma lipoprotein particle clearance GO:0034381 13 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
cellular lipid metabolic process GO:0044255 323 0.015
lymphocyte differentiation GO:0030098 242 0.015
neuron death GO:0070997 154 0.015
neuron apoptotic process GO:0051402 142 0.015
negative regulation of kinase activity GO:0033673 81 0.015
cation transmembrane transport GO:0098655 266 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
regulation of actin polymerization or depolymerization GO:0008064 45 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
mitotic cell cycle GO:0000278 195 0.014
interleukin 6 production GO:0032635 58 0.014
protein localization to membrane GO:0072657 108 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
regulation of organ morphogenesis GO:2000027 144 0.014
cellular ion homeostasis GO:0006873 165 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
regulation of receptor activity GO:0010469 41 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
protein processing GO:0016485 163 0.014
regulation of antibacterial peptide biosynthetic process GO:0002808 1 0.014
glycoprotein metabolic process GO:0009100 116 0.014
urogenital system development GO:0001655 261 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
positive regulation of defense response GO:0031349 124 0.014
rho protein signal transduction GO:0007266 32 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
establishment of synaptic vesicle localization GO:0097480 57 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
gtp catabolic process GO:0006184 143 0.013
regulation of lymphocyte mediated immunity GO:0002706 84 0.013
regulation of antimicrobial peptide production GO:0002784 1 0.013
dendrite development GO:0016358 115 0.013
chromatin modification GO:0016568 187 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
lipoprotein metabolic process GO:0042157 43 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
striated muscle contraction GO:0006941 45 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
response to nutrient levels GO:0031667 109 0.013
kidney development GO:0001822 213 0.013
appendage development GO:0048736 166 0.013
positive regulation of actin filament polymerization GO:0030838 26 0.013
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
regulation of intracellular transport GO:0032386 159 0.013
negative regulation of nervous system development GO:0051961 156 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
digestive tract development GO:0048565 190 0.012
Worm
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
skeletal system morphogenesis GO:0048705 203 0.012
nuclear division GO:0000280 158 0.012
fat cell differentiation GO:0045444 160 0.012
forebrain radial glial cell differentiation GO:0021861 4 0.012
regulation of protein localization GO:0032880 231 0.012
adaptive immune response GO:0002250 155 0.012
endodermal cell fate specification GO:0001714 4 0.012
Worm
response to acid chemical GO:0001101 111 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
fertilization GO:0009566 127 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
cell type specific apoptotic process GO:0097285 268 0.012
regulation of sterol transport GO:0032371 17 0.012
anion transport GO:0006820 177 0.012
hindbrain development GO:0030902 128 0.012
regulation of system process GO:0044057 200 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
ripoptosome assembly involved in necroptotic process GO:1901026 6 0.012
muscle contraction GO:0006936 101 0.012
positive regulation of cholesterol transport GO:0032376 9 0.012
regulation of cell activation GO:0050865 289 0.012
regulation of inflammatory response GO:0050727 147 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
Worm
rna processing GO:0006396 105 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.012
maintenance of location GO:0051235 89 0.012
regulation of neuron death GO:1901214 134 0.012
odontogenesis GO:0042476 78 0.012
jun phosphorylation GO:0007258 41 0.012
peptide metabolic process GO:0006518 46 0.012
positive regulation of binding GO:0051099 49 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
organophosphate catabolic process GO:0046434 232 0.012
glutamate receptor signaling pathway GO:0007215 35 0.012
positive regulation of cytoskeleton organization GO:0051495 49 0.012
cellular response to amino acid stimulus GO:0071230 29 0.012
regulation of protein ubiquitination GO:0031396 52 0.011
eyelid development in camera type eye GO:0061029 9 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.011
regulation of cellular ketone metabolic process GO:0010565 66 0.011
rna interference GO:0016246 2 0.011
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.011
circulatory system process GO:0003013 197 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
t cell activation GO:0042110 289 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
regulation of homeostatic process GO:0032844 182 0.011
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.011
nucleotide catabolic process GO:0009166 217 0.011
nuclear import GO:0051170 95 0.011
muscle cell fate specification GO:0042694 1 0.011
extracellular structure organization GO:0043062 148 0.011
positive regulation of antimicrobial humoral response GO:0002760 2 0.011
positive regulation of lipid transport GO:0032370 22 0.011
skeletal muscle organ development GO:0060538 163 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
tube closure GO:0060606 91 0.011
meiotic nuclear division GO:0007126 115 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
negative regulation of platelet derived growth factor receptor beta signaling pathway GO:2000587 2 0.011
asymmetric neuroblast division GO:0055059 1 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
asymmetric stem cell division GO:0098722 3 0.011
ras protein signal transduction GO:0007265 77 0.011
Worm
sequestering of metal ion GO:0051238 19 0.011
lymphocyte proliferation GO:0046651 164 0.011
cellular response to glucose stimulus GO:0071333 45 0.011
heart process GO:0003015 94 0.011
proteoglycan metabolic process GO:0006029 38 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
regulation of innate immune response GO:0045088 91 0.010
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.010
cellular amide metabolic process GO:0043603 58 0.010
regulation of synaptic transmission glutamatergic GO:0051966 19 0.010
cytokine metabolic process GO:0042107 71 0.010
endocytosis GO:0006897 168 0.010
defense response to virus GO:0051607 68 0.010
negative regulation of cell cycle GO:0045786 123 0.010
negative regulation of immune system process GO:0002683 209 0.010
cerebellum morphogenesis GO:0021587 42 0.010

Tab1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.178
diabetes mellitus DOID:9351 0 0.119
glucose metabolism disease DOID:4194 0 0.119
carbohydrate metabolism disease DOID:0050013 0 0.119
type 2 diabetes mellitus DOID:9352 0 0.119
acquired metabolic disease DOID:0060158 0 0.119
nervous system disease DOID:863 0 0.026
disease of anatomical entity DOID:7 0 0.026
gonadal dysgenesis DOID:14447 0 0.012
chromosomal disease DOID:0080014 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
immune system disease DOID:2914 0 0.011
neurodegenerative disease DOID:1289 0 0.011
central nervous system disease DOID:331 0 0.011
organ system cancer DOID:0050686 0 0.011
cancer DOID:162 0 0.011