|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.989
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.988
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.986
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.976
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.975
|
Zebrafish |
|
cytokine production
|
GO:0001816 |
319 |
0.975
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.971
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.971
|
|
|
response to atp
|
GO:0033198 |
8 |
0.970
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.967
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.965
|
|
|
dendritic cell dendrite assembly
|
GO:0097026 |
2 |
0.964
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.958
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.955
|
|
|
positive regulation of natural killer cell chemotaxis
|
GO:2000503 |
1 |
0.955
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.950
|
Zebrafish |
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.948
|
Human |
|
adaptive immune response
|
GO:0002250 |
155 |
0.938
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.937
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.935
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.932
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.929
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.927
|
Human |
|
positive regulation of neutrophil mediated killing of symbiont cell
|
GO:0070961 |
1 |
0.924
|
|
|
inflammatory response to wounding
|
GO:0090594 |
4 |
0.922
|
Mouse |
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.919
|
Human |
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.919
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.916
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.916
|
Human |
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.914
|
Human |
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.908
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.905
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.905
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.902
|
Human |
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.902
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.899
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.896
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.893
|
Human |
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.892
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.892
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.890
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.882
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.881
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.879
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.877
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.877
|
Human |
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.868
|
|
|
acute phase response
|
GO:0006953 |
10 |
0.867
|
|
|
adiponectin secretion
|
GO:0070162 |
2 |
0.865
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.861
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.858
|
Human |
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.857
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.856
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.851
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.848
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.845
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.844
|
Human |
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.832
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.826
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.824
|
Human |
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.822
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.821
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.820
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.819
|
Human |
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.817
|
Human |
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.817
|
Human |
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.813
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.809
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.808
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.808
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.807
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.798
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.796
|
|
|
neutrophil mediated killing of gram negative bacterium
|
GO:0070945 |
4 |
0.789
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.782
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.777
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.777
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.776
|
|
|
regulation of t helper 2 cell cytokine production
|
GO:2000551 |
3 |
0.774
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.769
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.764
|
Human |
|
granulocyte migration
|
GO:0097530 |
43 |
0.762
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.756
|
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
8 |
0.755
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.753
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.751
|
|
|
regulation of neutrophil mediated killing of symbiont cell
|
GO:0070949 |
2 |
0.743
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.742
|
Human Mouse |
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.737
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.732
|
|
|
positive regulation of macrophage chemotaxis
|
GO:0010759 |
5 |
0.717
|
|
|
regulation of vascular endothelial growth factor production
|
GO:0010574 |
13 |
0.712
|
|
|
positive regulation of neutrophil mediated cytotoxicity
|
GO:0070960 |
1 |
0.706
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.700
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.696
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.693
|
Human |
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.683
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.682
|
|
|
positive regulation of type 2 immune response
|
GO:0002830 |
9 |
0.663
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.657
|
|
|
positive regulation of dendritic cell dendrite assembly
|
GO:2000549 |
1 |
0.653
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.653
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.652
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.648
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.647
|
|
|
regulation of neutrophil mediated killing of gram negative bacterium
|
GO:0070951 |
1 |
0.645
|
|
|
b cell chemotaxis
|
GO:0035754 |
3 |
0.641
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.638
|
|
|
regulation of t helper 1 cell cytokine production
|
GO:2000554 |
1 |
0.638
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.638
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.638
|
|
|
wound healing involved in inflammatory response
|
GO:0002246 |
4 |
0.636
|
Mouse |
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
14 |
0.635
|
|
|
regulation of b cell chemotaxis
|
GO:2000537 |
2 |
0.633
|
|
|
regulation of immunoglobulin production in mucosal tissue
|
GO:2000557 |
1 |
0.630
|
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.622
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.622
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.620
|
|
|
detection of fungus
|
GO:0016046 |
2 |
0.617
|
|
|
positive regulation of b cell chemotaxis
|
GO:2000538 |
2 |
0.617
|
|
|
immunoglobulin production in mucosal tissue
|
GO:0002426 |
3 |
0.617
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.613
|
Human |
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.604
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.603
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.602
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.602
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.602
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.589
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.586
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.586
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.585
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.585
|
Mouse |
|
positive regulation of neuron death
|
GO:1901216 |
28 |
0.583
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.578
|
|
|
chemokine biosynthetic process
|
GO:0042033 |
8 |
0.578
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.576
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.575
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.575
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.574
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.572
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.569
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.568
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
29 |
0.568
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.564
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.564
|
Human |
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.562
|
Human |
|
regulation of fever generation
|
GO:0031620 |
6 |
0.560
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.556
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.555
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.553
|
Human Mouse |
|
positive regulation of immunoglobulin production in mucosal tissue
|
GO:2000558 |
1 |
0.552
|
|
|
regulation of thymocyte migration
|
GO:2000410 |
2 |
0.552
|
|
|
amide transport
|
GO:0042886 |
138 |
0.550
|
Human Mouse |
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.548
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.545
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.545
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.544
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.544
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.543
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.540
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.535
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.535
|
Human |
|
positive regulation of t helper 2 cell cytokine production
|
GO:2000553 |
3 |
0.534
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.525
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.525
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.525
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.524
|
|
|
negative regulation of necroptotic process
|
GO:0060546 |
9 |
0.522
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.521
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.520
|
|
|
wound healing
|
GO:0042060 |
157 |
0.519
|
Mouse |
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.519
|
|
|
regulation of fatty acid transport
|
GO:2000191 |
10 |
0.519
|
|
|
macrophage chemotaxis
|
GO:0048246 |
14 |
0.518
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.518
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.516
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.516
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.515
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.506
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.506
|
Human |
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.505
|
Human |
|
chemokine metabolic process
|
GO:0050755 |
10 |
0.504
|
|
|
regulation of natural killer cell chemotaxis
|
GO:2000501 |
1 |
0.503
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.496
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.496
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.493
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.490
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.482
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.481
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.477
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.469
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.467
|
Human |
|
positive regulation of lipid catabolic process
|
GO:0050996 |
6 |
0.467
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.467
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.461
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.460
|
Human |
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.459
|
|
|
natural killer cell chemotaxis
|
GO:0035747 |
1 |
0.457
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.455
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.452
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.443
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.443
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.442
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.439
|
Human |
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.437
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.436
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.429
|
|
|
positive regulation of chemokine secretion
|
GO:0090197 |
4 |
0.419
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.413
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.411
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.407
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.406
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.405
|
|
|
cd4 positive alpha beta t cell proliferation
|
GO:0035739 |
2 |
0.405
|
|
|
t helper 1 cell cytokine production
|
GO:0035744 |
1 |
0.405
|
|
|
interleukin 18 mediated signaling pathway
|
GO:0035655 |
2 |
0.403
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
11 |
0.402
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.396
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.393
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.392
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.387
|
Human |
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.384
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.383
|
Human |
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.381
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.380
|
|
|
prostaglandin transport
|
GO:0015732 |
7 |
0.378
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.378
|
|
|
negative regulation of interleukin 12 production
|
GO:0032695 |
10 |
0.377
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.376
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.373
|
|
|
positive regulation of t helper 1 cell cytokine production
|
GO:2000556 |
1 |
0.372
|
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.371
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.370
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.370
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.368
|
Human |
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.366
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.366
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.365
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.363
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.363
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.360
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.360
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.360
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.356
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.352
|
|
|
regulation of adiponectin secretion
|
GO:0070163 |
2 |
0.352
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.351
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.351
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.351
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.347
|
|
|
positive regulation of t helper 1 type immune response
|
GO:0002827 |
12 |
0.346
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.342
|
|
|
regulation of interleukin 1 alpha secretion
|
GO:0050705 |
3 |
0.341
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.341
|
|
|
macrophage apoptotic process
|
GO:0071888 |
7 |
0.341
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.338
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.337
|
|
|
regulation of neutrophil mediated cytotoxicity
|
GO:0070948 |
2 |
0.335
|
|
|
regulation of eosinophil migration
|
GO:2000416 |
2 |
0.335
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.333
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.333
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
9 |
0.329
|
|
|
positive regulation vascular endothelial growth factor production
|
GO:0010575 |
10 |
0.327
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.326
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.325
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.322
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.322
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
15 |
0.318
|
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.317
|
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.314
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.314
|
Human |
|
regulation of chemokine secretion
|
GO:0090196 |
4 |
0.309
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.308
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.307
|
|
|
positive regulation of chemokine biosynthetic process
|
GO:0045080 |
6 |
0.300
|
|
|
regulation of prostaglandin secretion
|
GO:0032306 |
5 |
0.296
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.294
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.291
|
|
|
regulation of anion transport
|
GO:0044070 |
27 |
0.290
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.287
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.287
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.287
|
Human Mouse |
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.286
|
|
|
vascular endothelial growth factor production
|
GO:0010573 |
13 |
0.286
|
|
|
activation of jun kinase activity
|
GO:0007257 |
15 |
0.284
|
|
|
negative regulation of myoblast differentiation
|
GO:0045662 |
18 |
0.284
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.283
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.283
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.280
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.277
|
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
15 |
0.275
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.274
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.274
|
Human |
|
regulation of dendritic cell dendrite assembly
|
GO:2000547 |
2 |
0.273
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.273
|
Human |
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.272
|
|
|
connective tissue replacement involved in inflammatory response wound healing
|
GO:0002248 |
3 |
0.272
|
Mouse |
|
activation of immune response
|
GO:0002253 |
138 |
0.270
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.269
|
Zebrafish |
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
17 |
0.267
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.265
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.263
|
Human |
|
immunoglobulin production
|
GO:0002377 |
73 |
0.263
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.263
|
|
|
interaction with symbiont
|
GO:0051702 |
14 |
0.262
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.261
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.261
|
Human |
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.259
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.259
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.258
|
Human |
|
pyroptosis
|
GO:0070269 |
8 |
0.255
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.254
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.253
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.253
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
14 |
0.251
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.250
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.249
|
Human |
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.249
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.247
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.244
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.244
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.244
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.244
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.243
|
|
|
regulation of neutrophil mediated killing of bacterium
|
GO:0070950 |
1 |
0.241
|
|
|
t cell chemotaxis
|
GO:0010818 |
6 |
0.241
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.237
|
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.236
|
|
|
interleukin 6 biosynthetic process
|
GO:0042226 |
12 |
0.236
|
|
|
detection of yeast
|
GO:0001879 |
2 |
0.235
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.235
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.234
|
|
|
positive regulation of fever generation
|
GO:0031622 |
6 |
0.233
|
|
|
mature natural killer cell chemotaxis
|
GO:0035782 |
1 |
0.233
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.230
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.229
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.229
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.228
|
Human |
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.227
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.226
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.226
|
Human |
|
positive regulation of organic acid transport
|
GO:0032892 |
11 |
0.226
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.226
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.225
|
|
|
neuron death
|
GO:0070997 |
154 |
0.224
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.223
|
|
|
positive regulation of macrophage activation
|
GO:0043032 |
10 |
0.222
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.222
|
Human |
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.220
|
|
|
regulation of myeloid cell apoptotic process
|
GO:0033032 |
19 |
0.219
|
|
|
regulation of organic acid transport
|
GO:0032890 |
16 |
0.219
|
|
|
positive regulation of prostaglandin secretion
|
GO:0032308 |
5 |
0.219
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.218
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.217
|
Human |
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.216
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.215
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.215
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.211
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.211
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.211
|
|
|
dendritic cell chemotaxis
|
GO:0002407 |
7 |
0.210
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
16 |
0.210
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.209
|
Human |
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.208
|
|
|
sperm individualization
|
GO:0007291 |
1 |
0.208
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.208
|
|
|
negative regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031665 |
3 |
0.207
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.206
|
|
|
interleukin 1 secretion
|
GO:0050701 |
16 |
0.206
|
|
|
icosanoid secretion
|
GO:0032309 |
12 |
0.205
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.203
|
|
|
fever generation
|
GO:0001660 |
7 |
0.201
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.200
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.200
|
Human |
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.200
|
Human |
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.199
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.197
|
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
33 |
0.196
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.196
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.196
|
|
|
protein processing
|
GO:0016485 |
163 |
0.194
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.193
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.193
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.192
|
Human |
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.192
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.191
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.191
|
Human |
|
interleukin 1 production
|
GO:0032612 |
31 |
0.191
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.190
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.189
|
|
|
negative regulation of glucose transport
|
GO:0010829 |
9 |
0.188
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.185
|
Human |
|
syncytium formation
|
GO:0006949 |
43 |
0.185
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
10 |
0.184
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.184
|
Human |
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.183
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.183
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.181
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.180
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.179
|
Human Mouse |
|
cation homeostasis
|
GO:0055080 |
212 |
0.179
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.178
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.177
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.176
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.176
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.176
|
Human |
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.176
|
|
|
icosanoid transport
|
GO:0071715 |
14 |
0.175
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.174
|
|
|
response to arsenic containing substance
|
GO:0046685 |
5 |
0.173
|
Zebrafish |
|
interleukin 33 mediated signaling pathway
|
GO:0038172 |
1 |
0.172
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.172
|
|
|
interleukin 1 alpha secretion
|
GO:0050703 |
3 |
0.171
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.171
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.170
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.169
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.168
|
|
|
antibacterial peptide secretion
|
GO:0002779 |
1 |
0.167
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.167
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.166
|
Human |
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.166
|
|
|
regulation of dendritic cell antigen processing and presentation
|
GO:0002604 |
7 |
0.166
|
|
|
positive regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000563 |
1 |
0.165
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.165
|
Human |
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.164
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.164
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.163
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.162
|
|
|
regulation of hematopoietic stem cell proliferation
|
GO:1902033 |
3 |
0.162
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.162
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.162
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.162
|
|
|
positive regulation of killing of cells of other organism
|
GO:0051712 |
3 |
0.160
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.160
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.160
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.159
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.159
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.159
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.159
|
|
|
positive regulation of neutrophil mediated killing of fungus
|
GO:0070965 |
1 |
0.159
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.158
|
|
|
positive regulation of hematopoietic stem cell proliferation
|
GO:1902035 |
2 |
0.157
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.157
|
|
|
disruption by host of symbiont cells
|
GO:0051852 |
11 |
0.156
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.156
|
|
|
positive regulation of interleukin 1 alpha secretion
|
GO:0050717 |
3 |
0.155
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.155
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.155
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.154
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.153
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.152
|
|
|
astrocyte cell migration
|
GO:0043615 |
3 |
0.151
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.150
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.149
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.148
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.148
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.147
|
|
|
heat generation
|
GO:0031649 |
13 |
0.146
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.144
|
|
|
positive regulation of glycoprotein metabolic process
|
GO:1903020 |
6 |
0.143
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.142
|
|
|
regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000561 |
2 |
0.142
|
|
|
negative regulation of chemokine production
|
GO:0032682 |
4 |
0.142
|
|
|
neutrophil mediated killing of bacterium
|
GO:0070944 |
6 |
0.142
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.142
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.139
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.137
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.137
|
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.135
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
35 |
0.135
|
|
|
regulation of icosanoid secretion
|
GO:0032303 |
8 |
0.135
|
|
|
dendritic cell antigen processing and presentation
|
GO:0002468 |
7 |
0.134
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.133
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.132
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.131
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.131
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.131
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.130
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.128
|
|
|
mucosal immune response
|
GO:0002385 |
13 |
0.128
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
11 |
0.128
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.127
|
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
9 |
0.126
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.126
|
Human |
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.126
|
Human |
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.124
|
|
|
detection of bacterium
|
GO:0016045 |
7 |
0.124
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.124
|
|
|
response to organophosphorus
|
GO:0046683 |
22 |
0.124
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.121
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.121
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.120
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.120
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.120
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.120
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.119
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.119
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.118
|
|
|
anion transport
|
GO:0006820 |
177 |
0.118
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.117
|
Zebrafish |