Mus musculus

21 known processes

Adam19

a disintegrin and metallopeptidase domain 19 (meltrin beta)

(Aliases: Mltnb,M[b],AL024287)

Adam19 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
extracellular matrix dependent thymocyte migration GO:0072680 1 1.000
Mouse
fibronectin dependent thymocyte migration GO:0072681 1 1.000
Mouse
positive regulation of thymocyte migration GO:2000412 2 1.000
Mouse
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 1.000
Mouse
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 1.000
Mouse
positive regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000309 1 0.999
Mouse
positive regulation of eosinophil migration GO:2000418 2 0.999
Mouse
eosinophil migration GO:0072677 3 0.999
Mouse
regulation of fibronectin dependent thymocyte migration GO:2000413 1 0.998
Mouse
activation of mapk activity involved in innate immune response GO:0035419 2 0.998
Mouse
prevention of polyspermy GO:0060468 4 0.997
Mouse
regulation of thymocyte migration GO:2000410 2 0.987
Mouse
bone remodeling GO:0046849 53 0.983
Mouse
regulation of eosinophil migration GO:2000416 2 0.982
Mouse
thymocyte migration GO:0072679 2 0.981
Mouse
substrate dependent cell migration GO:0006929 18 0.979
Mouse
positive regulation of t cell activation GO:0050870 101 0.978
Mouse
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.974
Mouse
t cell activation GO:0042110 289 0.972
Mouse
adaptive immune response GO:0002250 155 0.967
Mouse
multicellular organismal signaling GO:0035637 91 0.961
Mouse
heart morphogenesis GO:0003007 178 0.960
Mouse
action potential GO:0001508 78 0.957
Mouse
cell cell recognition GO:0009988 44 0.952
Mouse
regulation of mast cell apoptotic process GO:0033025 5 0.946
Mouse
cardiac epithelial to mesenchymal transition GO:0060317 18 0.938
Mouse
stem cell differentiation GO:0048863 268 0.928
Mouse
single organismal cell cell adhesion GO:0016337 131 0.919
Mouse
myelination in peripheral nervous system GO:0022011 19 0.908
Mouse
t cell differentiation in thymus GO:0033077 77 0.907
Mouse
cell recognition GO:0008037 83 0.896
Mouse
mesenchyme development GO:0060485 152 0.896
Mouse
epithelial to mesenchymal transition GO:0001837 47 0.893
Mouse
positive regulation of lymphocyte migration GO:2000403 11 0.891
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.885
Mouse
chemotaxis GO:0006935 247 0.882
Mouse
myelination GO:0042552 74 0.882
Mouse
stem cell development GO:0048864 219 0.880
Mouse
transmission of nerve impulse GO:0019226 76 0.880
Mouse
positive regulation of lymphocyte apoptotic process GO:0070230 13 0.876
Mouse
activation of mapk activity GO:0000187 59 0.874
Mouse
negative regulation of fertilization GO:0060467 5 0.867
Mouse
rac protein signal transduction GO:0016601 13 0.862
axon guidance GO:0007411 141 0.848
regulation of t cell activation GO:0050863 170 0.846
Mouse
sperm egg recognition GO:0035036 37 0.843
Mouse
axon target recognition GO:0007412 4 0.838
schwann cell differentiation GO:0014037 26 0.838
Mouse
single organism cell adhesion GO:0098602 156 0.832
Mouse
regulation of cell migration GO:0030334 219 0.816
Mouse
cell adhesion GO:0007155 329 0.808
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.801
Mouse
visual behavior GO:0007632 45 0.800
Mouse
immune response regulating signaling pathway GO:0002764 125 0.787
Mouse
leukocyte homeostasis GO:0001776 79 0.783
Mouse
activation of immune response GO:0002253 138 0.779
Mouse
bone resorption GO:0045453 38 0.774
Mouse
ensheathment of neurons GO:0007272 76 0.770
Mouse
mitral valve morphogenesis GO:0003183 4 0.768
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.767
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.757
Mouse
myeloid cell apoptotic process GO:0033028 22 0.752
Mouse
schwann cell development GO:0014044 22 0.750
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.747
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.745
negative regulation of multi organism process GO:0043901 68 0.726
Mouse
regulation of t cell differentiation GO:0045580 83 0.723
Mouse
regulation of transferase activity GO:0051338 263 0.721
Mouse
blood vessel morphogenesis GO:0048514 285 0.705
Mouse
spleen development GO:0048536 39 0.690
Mouse
regulation of lymphocyte migration GO:2000401 14 0.689
Mouse
lymphocyte migration GO:0072676 26 0.686
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.683
Mouse
mesenchymal cell development GO:0014031 93 0.681
Mouse
cognition GO:0050890 149 0.680
Mouse
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.678
Mouse
tissue remodeling GO:0048771 102 0.674
Mouse
neuronal action potential GO:0019228 54 0.672
Mouse
positive regulation of thymocyte apoptotic process GO:0070245 5 0.668
Mouse
positive regulation of protein catabolic process GO:0045732 60 0.656
Mouse
regulation of cell activation GO:0050865 289 0.652
Mouse
negative regulation of neuron death GO:1901215 98 0.648
Mouse
cardiac muscle hypertrophy in response to stress GO:0014898 10 0.645
angiogenesis GO:0001525 201 0.643
Mouse
regulation of t cell differentiation in thymus GO:0033081 24 0.641
Mouse
positive regulation of cell activation GO:0050867 158 0.640
Mouse
heart valve development GO:0003170 23 0.640
aortic valve morphogenesis GO:0003180 4 0.639
mesenchymal cell differentiation GO:0048762 107 0.639
Mouse
regulation of cellular catabolic process GO:0031329 242 0.636
Mouse
t cell proliferation GO:0042098 120 0.634
osteoclast differentiation GO:0030316 62 0.634
positive regulation of mapk cascade GO:0043410 170 0.630
Mouse
innate immune response activating signal transduction GO:0002758 50 0.627
Mouse
positive regulation of acute inflammatory response GO:0002675 16 0.627
Mouse
lymphocyte differentiation GO:0030098 242 0.620
Mouse
leukocyte differentiation GO:0002521 342 0.618
Mouse
gliogenesis GO:0042063 141 0.605
Mouse
positive regulation of kinase activity GO:0033674 155 0.603
Mouse
axonogenesis GO:0007409 274 0.603
positive regulation of cell migration GO:0030335 109 0.599
Mouse
regulation of membrane potential GO:0042391 192 0.594
Mouse
positive regulation of leukocyte apoptotic process GO:2000108 21 0.592
Mouse
positive regulation of protein kinase b signaling GO:0051897 32 0.585
Mouse
positive regulation of t cell differentiation GO:0045582 52 0.582
Mouse
regulation of lymphocyte apoptotic process GO:0070228 41 0.580
Mouse
positive regulation of programmed cell death GO:0043068 218 0.573
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.570
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.568
single fertilization GO:0007338 82 0.558
Mouse
regulation of innate immune response GO:0045088 91 0.549
Mouse
mast cell apoptotic process GO:0033024 5 0.545
Mouse
lymphocyte chemotaxis GO:0048247 10 0.538
Mouse
glial cell development GO:0021782 54 0.533
Mouse
egg activation GO:0007343 7 0.531
Mouse
locomotory behavior GO:0007626 195 0.527
Mouse
positive regulation of transferase activity GO:0051347 167 0.526
Mouse
lymphocyte proliferation GO:0046651 164 0.518
leukocyte chemotaxis GO:0030595 69 0.517
Mouse
positive regulation of t cell apoptotic process GO:0070234 8 0.517
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.514
Mouse
cell chemotaxis GO:0060326 81 0.507
Mouse
regulation of cell adhesion mediated by integrin GO:0033628 13 0.507
positive regulation of lymphocyte activation GO:0051251 140 0.504
Mouse
response to transforming growth factor beta GO:0071559 88 0.497
Mouse
regulation of thymocyte apoptotic process GO:0070243 14 0.492
Mouse
fertilization GO:0009566 127 0.491
Mouse
regulation of t cell proliferation GO:0042129 92 0.486
positive regulation of t cell differentiation in thymus GO:0033089 13 0.483
Mouse
tissue migration GO:0090130 68 0.483
binding of sperm to zona pellucida GO:0007339 34 0.483
Mouse
cell adhesion mediated by integrin GO:0033627 18 0.480
activation of innate immune response GO:0002218 56 0.470
Mouse
positive regulation of lymphocyte differentiation GO:0045621 61 0.466
Mouse
regulation of rho protein signal transduction GO:0035023 71 0.461
pulmonary valve development GO:0003177 5 0.451
t cell differentiation GO:0030217 174 0.450
Mouse
germinal center formation GO:0002467 16 0.447
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.444
cell type specific apoptotic process GO:0097285 268 0.443
Mouse
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.436
Mouse
positive regulation of leukocyte differentiation GO:1902107 86 0.435
Mouse
regulation of myeloid cell apoptotic process GO:0033032 19 0.432
Mouse
regulation of map kinase activity GO:0043405 120 0.426
Mouse
regulation of gtp catabolic process GO:0033124 113 0.425
regulation of cellular response to growth factor stimulus GO:0090287 82 0.422
Mouse
blood vessel lumenization GO:0072554 2 0.421
regulation of reproductive process GO:2000241 66 0.417
Mouse
thymocyte apoptotic process GO:0070242 19 0.413
Mouse
positive regulation of bone resorption GO:0045780 13 0.409
Mouse
epidermis development GO:0008544 187 0.406
glial cell differentiation GO:0010001 131 0.405
Mouse
immune response activating signal transduction GO:0002757 116 0.403
Mouse
regulation of lymphocyte activation GO:0051249 240 0.401
Mouse
neuron projection guidance GO:0097485 141 0.395
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.390
Mouse
negative regulation of neuron apoptotic process GO:0043524 92 0.390
Mouse
response to corticosteroid GO:0031960 20 0.387
Mouse
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.386
Mouse
b cell differentiation GO:0030183 78 0.377
Mouse
homeostasis of number of cells GO:0048872 210 0.370
Mouse
regulation of homeostatic process GO:0032844 182 0.370
Mouse
positive regulation of homeostatic process GO:0032846 64 0.368
Mouse
actin filament organization GO:0007015 113 0.368
regulation of purine nucleotide metabolic process GO:1900542 169 0.367
response to radiation GO:0009314 165 0.362
Mouse
positive regulation of nucleotide metabolic process GO:0045981 114 0.361
regulation of kinase activity GO:0043549 249 0.361
Mouse
cellular amino acid metabolic process GO:0006520 103 0.355
muscle hypertrophy in response to stress GO:0003299 10 0.355
regulation of neuron apoptotic process GO:0043523 122 0.353
Mouse
ascending aorta development GO:0035905 3 0.350
cellular extravasation GO:0045123 17 0.349
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.348
Mouse
positive regulation of innate immune response GO:0045089 80 0.343
Mouse
regulation of tissue remodeling GO:0034103 38 0.342
Mouse
adult locomotory behavior GO:0008344 91 0.342
Mouse
positive regulation of bone remodeling GO:0046852 13 0.340
Mouse
membrane protein ectodomain proteolysis GO:0006509 7 0.339
positive regulation of inflammatory response GO:0050729 47 0.338
Mouse
pulmonary artery morphogenesis GO:0061156 3 0.336
dendritic spine development GO:0060996 30 0.335
regulation of cell motility GO:2000145 236 0.334
Mouse
regulation of bone remodeling GO:0046850 28 0.333
Mouse
purine containing compound catabolic process GO:0072523 213 0.331
regulation of bone resorption GO:0045124 24 0.330
Mouse
response to steroid hormone GO:0048545 56 0.330
Mouse
regulation of neuron projection development GO:0010975 169 0.329
purine ribonucleotide metabolic process GO:0009150 290 0.329
positive regulation of response to wounding GO:1903036 66 0.327
Mouse
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.325
Mouse
adult behavior GO:0030534 135 0.325
Mouse
regulation of acute inflammatory response GO:0002673 27 0.322
Mouse
regulation of ras gtpase activity GO:0032318 88 0.316
neuron apoptotic process GO:0051402 142 0.315
Mouse
innate immune response GO:0045087 157 0.313
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.312
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.307
leukocyte migration involved in inflammatory response GO:0002523 7 0.304
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.304
Mouse
positive regulation of defense response GO:0031349 124 0.303
Mouse
tricuspid valve formation GO:0003195 2 0.292
regulation of cellular amine metabolic process GO:0033238 20 0.292
ribonucleotide metabolic process GO:0009259 291 0.291
protein catabolic process GO:0030163 221 0.290
Mouse
cardioblast migration GO:0003260 1 0.289
blood vessel endothelial cell migration GO:0043534 23 0.285
axon ensheathment GO:0008366 76 0.285
Mouse
regulation of mapk cascade GO:0043408 248 0.284
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.281
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.280
endocardial cushion to mesenchymal transition GO:0090500 5 0.280
regulation of multi organism process GO:0043900 111 0.280
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.279
positive regulation of cell death GO:0010942 224 0.279
Mouse
regulation of epithelial to mesenchymal transition GO:0010717 22 0.276
synaptic transmission GO:0007268 329 0.271
ras protein signal transduction GO:0007265 77 0.266
regulation of rho gtpase activity GO:0032319 58 0.263
guanosine containing compound catabolic process GO:1901069 144 0.262
kidney development GO:0001822 213 0.261
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.240
Mouse
muscle system process GO:0003012 141 0.240
mitral valve development GO:0003174 4 0.233
nucleoside catabolic process GO:0009164 206 0.230
positive regulation of cell motility GO:2000147 116 0.230
Mouse
atrial septum primum morphogenesis GO:0003289 3 0.227
nucleoside phosphate metabolic process GO:0006753 338 0.225
epithelial cell differentiation involved in kidney development GO:0035850 23 0.223
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.223
regulation of cytokine production GO:0001817 266 0.221
Mouse
regulation of cell projection organization GO:0031344 206 0.220
mapk cascade GO:0000165 281 0.220
Mouse
epithelial cell migration GO:0010631 63 0.218
glycosyl compound catabolic process GO:1901658 206 0.218
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.214
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.214
Mouse
regulation of protein kinase b signaling GO:0051896 56 0.214
Mouse
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.211
positive regulation of epidermal growth factor activated receptor activity GO:0045741 2 0.210
cell migration to the midline involved in heart development GO:0003318 1 0.207
b cell activation GO:0042113 161 0.207
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.201
negative regulation of cell migration GO:0030336 59 0.201
positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 12 0.200
Mouse
acute inflammatory response GO:0002526 41 0.200
Mouse
regulation of vasculogenesis GO:2001212 9 0.200
regulation of dendritic spine morphogenesis GO:0061001 17 0.199
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.195
Mouse
leukocyte migration GO:0050900 124 0.194
Mouse
compartment pattern specification GO:0007386 4 0.192
negative regulation of molecular function GO:0044092 258 0.191
myeloid cell differentiation GO:0030099 233 0.185
regulation of rac protein signal transduction GO:0035020 19 0.184
negative regulation of cellular component organization GO:0051129 194 0.184
membrane protein proteolysis GO:0033619 10 0.182
organophosphate catabolic process GO:0046434 232 0.182
rho protein signal transduction GO:0007266 32 0.182
gtp catabolic process GO:0006184 143 0.181
regulation of cardioblast differentiation GO:0051890 3 0.181
anatomical structure homeostasis GO:0060249 145 0.181
Mouse
negative regulation of ras protein signal transduction GO:0046580 18 0.181
striated muscle hypertrophy GO:0014897 24 0.180
learning or memory GO:0007611 148 0.180
Mouse
regulation of glial cell differentiation GO:0045685 41 0.180
myeloid cell homeostasis GO:0002262 114 0.178
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.171
Mouse
learning GO:0007612 98 0.169
Mouse
negative regulation of cell proliferation GO:0008285 296 0.166
regulation of cellular ketone metabolic process GO:0010565 66 0.165
regulation of response to wounding GO:1903034 189 0.164
Mouse
cellular amine metabolic process GO:0044106 44 0.163
lymphocyte apoptotic process GO:0070227 54 0.163
Mouse
regulation of chromosome organization GO:0033044 83 0.162
t cell apoptotic process GO:0070231 39 0.161
Mouse
response to organic cyclic compound GO:0014070 198 0.160
Mouse
response to growth factor GO:0070848 198 0.158
Mouse
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.157
visual learning GO:0008542 44 0.157
Mouse
clara cell differentiation GO:0060486 4 0.156
multicellular organismal homeostasis GO:0048871 164 0.155
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.154
cardiac muscle tissue development GO:0048738 130 0.154
regulation of nucleotide catabolic process GO:0030811 122 0.152
regulation of microvillus organization GO:0032530 3 0.152
negative regulation of neuron projection regeneration GO:0070571 3 0.149
regulation of protein kinase activity GO:0045859 232 0.148
Mouse
amine metabolic process GO:0009308 45 0.148
positive regulation of cell adhesion GO:0045785 80 0.147
Mouse
negative regulation of dendrite development GO:2000171 9 0.145
nucleoside metabolic process GO:0009116 246 0.145
cellular response to cytokine stimulus GO:0071345 189 0.144
megakaryocyte differentiation GO:0030219 26 0.143
associative learning GO:0008306 61 0.143
Mouse
positive regulation of tissue remodeling GO:0034105 19 0.142
Mouse
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.141
Mouse
glycoprotein biosynthetic process GO:0009101 89 0.141
telencephalon development GO:0021537 186 0.140
purine ribonucleotide catabolic process GO:0009154 208 0.140
regulation of leukocyte proliferation GO:0070663 121 0.139
purine nucleoside metabolic process GO:0042278 241 0.137
positive regulation of protein kinase activity GO:0045860 144 0.137
Mouse
regulation of glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000733 1 0.134
striated muscle adaptation GO:0014888 26 0.133
response to light stimulus GO:0009416 135 0.133
Mouse
retinal ganglion cell axon guidance GO:0031290 18 0.131
regulation of neuron death GO:1901214 134 0.129
Mouse
regulation of leukocyte apoptotic process GO:2000106 56 0.129
Mouse
tissue homeostasis GO:0001894 115 0.128
Mouse
peptidyl amino acid modification GO:0018193 336 0.126
purine nucleotide metabolic process GO:0006163 302 0.126
negative regulation of cellular amine metabolic process GO:0033239 1 0.126
cellular ketone metabolic process GO:0042180 84 0.125
regulation of organelle organization GO:0033043 289 0.125
negative regulation of interleukin 8 production GO:0032717 1 0.124
negative regulation of neuron projection development GO:0010977 50 0.120
cardiac muscle cell contraction GO:0086003 7 0.120
skin development GO:0043588 220 0.120
ribonucleoside metabolic process GO:0009119 245 0.119
negative regulation of nervous system development GO:0051961 156 0.118
ribonucleoside catabolic process GO:0042454 206 0.118
ribonucleotide catabolic process GO:0009261 208 0.116
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.116
Mouse
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.115
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.115
Mouse
negative regulation of cell fate specification GO:0009996 4 0.112
purine ribonucleoside metabolic process GO:0046128 241 0.112
regulation of t cell apoptotic process GO:0070232 28 0.111
Mouse
regulation of hormone secretion GO:0046883 88 0.110
skeletal muscle organ development GO:0060538 163 0.110
regulation of cardiac cell fate specification GO:2000043 1 0.108
negative regulation of reproductive process GO:2000242 31 0.108
Mouse
embryonic organ morphogenesis GO:0048562 276 0.107
ventricular cardiac muscle cell action potential GO:0086005 4 0.107
positive regulation of protein modification process GO:0031401 299 0.107
Mouse
pulmonary valve morphogenesis GO:0003184 5 0.106
glycoprotein metabolic process GO:0009100 116 0.106
regulation of epithelial cell migration GO:0010632 35 0.106
cell substrate adhesion GO:0031589 130 0.105
regulation of peptide hormone secretion GO:0090276 75 0.104
leukocyte proliferation GO:0070661 172 0.103
negative regulation of cell development GO:0010721 169 0.102
epidermis morphogenesis GO:0048730 33 0.102
tricuspid valve morphogenesis GO:0003186 2 0.102
positive regulation of cardioblast differentiation GO:0051891 3 0.101
ameboidal type cell migration GO:0001667 128 0.100
wound healing GO:0042060 157 0.099
urogenital system development GO:0001655 261 0.099
granulocyte migration GO:0097530 43 0.098
Mouse
regulation of actin filament based process GO:0032970 99 0.098
cardiac muscle hypertrophy GO:0003300 23 0.097
developmental maturation GO:0021700 193 0.097
cardiac muscle adaptation GO:0014887 10 0.096
sensory system development GO:0048880 3 0.096
regulation of system process GO:0044057 200 0.096
negative regulation of myeloid cell differentiation GO:0045638 38 0.095
hematopoietic progenitor cell differentiation GO:0002244 143 0.095
extrinsic apoptotic signaling pathway GO:0097191 126 0.094
glial cell fate determination GO:0007403 3 0.094
organonitrogen compound biosynthetic process GO:1901566 192 0.094
sensory organ morphogenesis GO:0090596 242 0.094
insulin secretion GO:0030073 89 0.093
trabecula morphogenesis GO:0061383 40 0.093
purine nucleotide catabolic process GO:0006195 211 0.092
neuron migration GO:0001764 122 0.092
layer formation in cerebral cortex GO:0021819 13 0.092
positive regulation of cellular amine metabolic process GO:0033240 5 0.092
regulation of inflammatory response GO:0050727 147 0.092
Mouse
regulation of auditory receptor cell differentiation GO:0045607 4 0.091
anion transport GO:0006820 177 0.090
epithelial tube morphogenesis GO:0060562 303 0.090
nucleotide catabolic process GO:0009166 217 0.090
cation homeostasis GO:0055080 212 0.090
purine nucleoside triphosphate metabolic process GO:0009144 226 0.089
regulation of myeloid cell differentiation GO:0045637 96 0.087
glomerulus development GO:0032835 40 0.086
positive regulation of proteolysis GO:0045862 85 0.086
Mouse
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.086
female gamete generation GO:0007292 74 0.085
ventricular septum morphogenesis GO:0060412 27 0.085
mesodermal cell migration GO:0008078 4 0.085
negative regulation of mitotic cell cycle embryonic GO:0045976 2 0.085
ribose phosphate metabolic process GO:0019693 291 0.085
positive regulation of t cell migration GO:2000406 10 0.084
Mouse
camera type eye development GO:0043010 266 0.084
dorsal aorta morphogenesis GO:0035912 5 0.084
myeloid leukocyte migration GO:0097529 57 0.083
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.082
negative regulation of osteoclast differentiation GO:0045671 12 0.082
regulation of purine nucleotide catabolic process GO:0033121 122 0.080
rhombomere morphogenesis GO:0021593 2 0.080
regulation of heart contraction GO:0008016 77 0.080
renal system development GO:0072001 225 0.080
regulation of dendritic spine development GO:0060998 22 0.080
gland development GO:0048732 330 0.079
regulation of proteolysis GO:0030162 164 0.079
Mouse
regulation of cardiac muscle tissue development GO:0055024 31 0.079
cellular response to hormone stimulus GO:0032870 150 0.078
regulation of nucleotide metabolic process GO:0006140 169 0.078
cellular response to lipopolysaccharide GO:0071222 77 0.078
regulation of secretion by cell GO:1903530 249 0.077
peptide hormone secretion GO:0030072 109 0.076
regulation of gliogenesis GO:0014013 50 0.075
notochord formation GO:0014028 5 0.075
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.075
epithelium migration GO:0090132 63 0.074
cellular glucose homeostasis GO:0001678 52 0.074
negative regulation of epithelial to mesenchymal transition GO:0010719 6 0.074
regulation of peptide transport GO:0090087 91 0.074
pro t cell differentiation GO:0002572 3 0.073
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.073
negative regulation of leukocyte differentiation GO:1902106 51 0.073
endodermal cell fate commitment GO:0001711 12 0.073
epithelial cell proliferation GO:0050673 174 0.073
mesonephric tubule development GO:0072164 94 0.072
response to monosaccharide GO:0034284 67 0.072
glycosyl compound metabolic process GO:1901657 246 0.072
cellular nitrogen compound catabolic process GO:0044270 280 0.071
macromolecule catabolic process GO:0009057 281 0.071
Mouse
multicellular organism growth GO:0035264 161 0.071
antigen receptor mediated signaling pathway GO:0050851 64 0.070
cardiocyte differentiation GO:0035051 87 0.070
transcriptional activation by promoter enhancer looping GO:0071733 2 0.069
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.069
forebrain development GO:0030900 302 0.068
positive regulation of interleukin 13 production GO:0032736 4 0.068
negative regulation of immune system process GO:0002683 209 0.067
cellular homeostasis GO:0019725 240 0.067
regulation of binding GO:0051098 111 0.067
germ cell development GO:0007281 185 0.067
ribonucleoside triphosphate metabolic process GO:0009199 220 0.067
tricuspid valve development GO:0003175 3 0.066
fasciculation of sensory neuron axon GO:0097155 3 0.066
leukocyte apoptotic process GO:0071887 71 0.066
Mouse
cytosolic calcium ion transport GO:0060401 48 0.065
neuron death GO:0070997 154 0.065
Mouse
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.065
regulation of protein catabolic process GO:0042176 108 0.064
Mouse
actin cytoskeleton organization GO:0030036 220 0.064
keratinocyte migration GO:0051546 3 0.064
blood circulation GO:0008015 195 0.064
detection of external stimulus GO:0009581 61 0.063
regulation of cell adhesion GO:0030155 154 0.063
Mouse
notochord morphogenesis GO:0048570 10 0.062
regulation of neuronal synaptic plasticity GO:0048168 30 0.062
endothelial cell migration GO:0043542 44 0.062
dendritic spine morphogenesis GO:0060997 22 0.061
cerebral cortex cell migration GO:0021795 44 0.061
adult walking behavior GO:0007628 41 0.061
pallium development GO:0021543 120 0.061
membrane organization GO:0061024 245 0.061
regulation of stem cell differentiation GO:2000736 50 0.061
response to glucocorticoid GO:0051384 20 0.060
Mouse
regulation of rac gtpase activity GO:0032314 13 0.060
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.060
regulation of endothelial cell migration GO:0010594 22 0.060
heart growth GO:0060419 45 0.059
negative regulation of protein modification process GO:0031400 163 0.059
regulation of protein transport GO:0051223 163 0.059
neuron recognition GO:0008038 25 0.059
negative regulation of cell adhesion GO:0007162 45 0.058
ephrin receptor signaling pathway GO:0048013 20 0.058
purine nucleoside catabolic process GO:0006152 205 0.058
atrioventricular valve morphogenesis GO:0003181 13 0.058
inflammatory response GO:0006954 244 0.058
Mouse
regulation of peptide secretion GO:0002791 77 0.057
embryonic heart tube development GO:0035050 65 0.057
response to molecule of bacterial origin GO:0002237 143 0.056
cardiac muscle cell action potential involved in contraction GO:0086002 6 0.056
negative regulation of cell motility GO:2000146 61 0.056
nephron development GO:0072006 109 0.056
regulation of muscle tissue development GO:1901861 97 0.055
regulation of histone h3 k4 methylation GO:0051569 12 0.055
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.055
cell migration involved in sprouting angiogenesis GO:0002042 9 0.055
response to retinoic acid GO:0032526 56 0.055
regulation of establishment of protein localization GO:0070201 181 0.055
heart valve morphogenesis GO:0003179 21 0.055
regulation of blood circulation GO:1903522 93 0.054
fasciculation of motor neuron axon GO:0097156 2 0.054
positive regulation of nervous system development GO:0051962 221 0.054
skin morphogenesis GO:0043589 38 0.054
extracellular matrix organization GO:0030198 147 0.054
central nervous system projection neuron axonogenesis GO:0021952 21 0.053
nucleoside phosphate catabolic process GO:1901292 222 0.053
wound healing spreading of cells GO:0044319 8 0.053
positive regulation of map kinase activity GO:0043406 84 0.053
Mouse
neuroblast differentiation GO:0014016 2 0.053
av node cell to bundle of his cell communication GO:0086067 2 0.053
positive regulation of cytokine production GO:0001819 174 0.053
Mouse
muscle hypertrophy GO:0014896 24 0.052

Adam19 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.854
disease of anatomical entity DOID:7 0 0.854
cardiovascular system disease DOID:1287 0 0.854
musculoskeletal system disease DOID:17 0 0.120
muscular disease DOID:0080000 0 0.117
congenital heart disease DOID:1682 0 0.117
heart septal defect DOID:1681 0 0.095
muscle tissue disease DOID:66 0 0.080