Mus musculus

38 known processes

Akap8

A kinase (PRKA) anchor protein 8

(Aliases: 1200016A02Rik,AA673585,AKAP95,AU015639)

Akap8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna processing GO:0006397 63 0.616
rna processing GO:0006396 105 0.579
mrna splicing via spliceosome GO:0000398 43 0.398
regulation of mrna metabolic process GO:1903311 43 0.182
regulation of mrna splicing via spliceosome GO:0048024 32 0.167
regulation of nuclear division GO:0051783 56 0.149
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.136
mrna metabolic process GO:0016071 84 0.130
posttranscriptional regulation of gene expression GO:0010608 155 0.115
regulation of organelle organization GO:0033043 289 0.105
organic cyclic compound catabolic process GO:1901361 295 0.102
heterocycle catabolic process GO:0046700 280 0.097
regulation of mrna processing GO:0050684 41 0.086
rna splicing GO:0008380 54 0.077
cellular ketone metabolic process GO:0042180 84 0.074
mitotic cell cycle GO:0000278 195 0.071
regulation of rna splicing GO:0043484 37 0.067
organelle fission GO:0048285 170 0.066
stem cell development GO:0048864 219 0.062
alternative mrna splicing via spliceosome GO:0000380 12 0.062
multicellular organism growth GO:0035264 161 0.057
microtubule based process GO:0007017 236 0.056
covalent chromatin modification GO:0016569 163 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.052
dna repair GO:0006281 107 0.052
peptidyl amino acid modification GO:0018193 336 0.050
germ cell development GO:0007281 185 0.050
gene silencing by rna GO:0031047 19 0.049
rna splicing via transesterification reactions GO:0000375 43 0.045
guanosine containing compound metabolic process GO:1901068 144 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
membrane organization GO:0061024 245 0.043
regulation of alternative mrna splicing via spliceosome GO:0000381 8 0.042
amine metabolic process GO:0009308 45 0.042
aromatic compound catabolic process GO:0019439 286 0.041
mitotic cell cycle process GO:1903047 159 0.040
dna metabolic process GO:0006259 303 0.039
organophosphate catabolic process GO:0046434 232 0.039
cellular nitrogen compound catabolic process GO:0044270 280 0.039
nuclear transport GO:0051169 139 0.039
nuclear division GO:0000280 158 0.038
apoptotic signaling pathway GO:0097190 306 0.037
cytoplasmic transport GO:0016482 234 0.037
negative regulation of mrna processing GO:0050686 12 0.036
regionalization GO:0003002 337 0.036
cellular amine metabolic process GO:0044106 44 0.036
immune effector process GO:0002252 321 0.035
epithelial to mesenchymal transition GO:0001837 47 0.035
cell adhesion GO:0007155 329 0.033
ribonucleotide catabolic process GO:0009261 208 0.033
positive regulation of cell death GO:0010942 224 0.033
rna interference GO:0016246 2 0.032
nitrogen compound transport GO:0071705 271 0.032
nucleoside metabolic process GO:0009116 246 0.032
posttranscriptional gene silencing GO:0016441 10 0.032
posttranscriptional gene silencing by rna GO:0035194 10 0.032
regulation of cellular response to stress GO:0080135 159 0.031
regulation of cell cycle process GO:0010564 160 0.031
regulation of apoptotic signaling pathway GO:2001233 197 0.030
regulation of cellular catabolic process GO:0031329 242 0.030
spermatid differentiation GO:0048515 115 0.029
spermatogenesis GO:0007283 284 0.029
positive regulation of apoptotic process GO:0043065 217 0.029
response to nutrient levels GO:0031667 109 0.029
gonad development GO:0008406 141 0.028
homeostasis of number of cells GO:0048872 210 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.027
purine containing compound metabolic process GO:0072521 311 0.027
cellular lipid metabolic process GO:0044255 323 0.027
mitotic nuclear division GO:0007067 48 0.027
placenta development GO:0001890 140 0.027
digestive tract development GO:0048565 190 0.025
cellular macromolecule catabolic process GO:0044265 206 0.024
macromolecule catabolic process GO:0009057 281 0.024
positive regulation of innate immune response GO:0045089 80 0.024
cellular amino acid metabolic process GO:0006520 103 0.024
response to light stimulus GO:0009416 135 0.023
leukocyte differentiation GO:0002521 342 0.023
regulation of cell activation GO:0050865 289 0.023
nucleocytoplasmic transport GO:0006913 139 0.022
axonogenesis GO:0007409 274 0.021
positive regulation of growth GO:0045927 104 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
regulation of cell shape GO:0008360 39 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
negative regulation of mrna metabolic process GO:1903312 13 0.021
development of primary sexual characteristics GO:0045137 143 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.020
mesenchyme development GO:0060485 152 0.020
regulation of membrane potential GO:0042391 192 0.020
negative regulation of cytokine production GO:0001818 84 0.020
regulation of organ morphogenesis GO:2000027 144 0.020
action potential GO:0001508 78 0.020
adult locomotory behavior GO:0008344 91 0.020
regulation of hormone levels GO:0010817 211 0.020
glycerolipid metabolic process GO:0046486 122 0.020
nucleoside catabolic process GO:0009164 206 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
peptidyl lysine modification GO:0018205 77 0.019
positive regulation of apoptotic signaling pathway GO:2001235 95 0.019
cytokine production GO:0001816 319 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.018
internal protein amino acid acetylation GO:0006475 42 0.018
mitochondrion organization GO:0007005 134 0.018
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.018
actin cytoskeleton organization GO:0030036 220 0.017
digestive tract morphogenesis GO:0048546 147 0.017
multicellular organismal signaling GO:0035637 91 0.017
skin development GO:0043588 220 0.017
regulation of defense response GO:0031347 233 0.017
protein localization to nucleus GO:0034504 121 0.017
gastrulation GO:0007369 116 0.017
stem cell differentiation GO:0048863 268 0.017
cation transmembrane transport GO:0098655 266 0.017
regulation of mrna stability GO:0043488 23 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
stem cell maintenance GO:0019827 130 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
development of primary female sexual characteristics GO:0046545 73 0.016
calcium ion homeostasis GO:0055074 127 0.016
cell type specific apoptotic process GO:0097285 268 0.016
mesenchymal cell development GO:0014031 93 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
dendrite development GO:0016358 115 0.016
mesenchymal cell differentiation GO:0048762 107 0.016
gene silencing by mirna GO:0035195 10 0.016
response to extracellular stimulus GO:0009991 127 0.016
histone methylation GO:0016571 71 0.016
protein acylation GO:0043543 64 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
inflammatory response GO:0006954 244 0.015
protein targeting GO:0006605 143 0.015
cellular protein complex assembly GO:0043623 116 0.015
microtubule cytoskeleton organization GO:0000226 157 0.015
wnt signaling pathway GO:0016055 188 0.015
negative regulation of organelle organization GO:0010639 90 0.015
endoderm development GO:0007492 45 0.015
locomotory behavior GO:0007626 195 0.015
response to temperature stimulus GO:0009266 55 0.015
regulation of protein stability GO:0031647 52 0.015
gland development GO:0048732 330 0.015
humoral immune response GO:0006959 57 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
spermatid development GO:0007286 108 0.014
defense response to other organism GO:0098542 197 0.014
morphogenesis of a polarized epithelium GO:0001738 37 0.014
negative regulation of protein modification process GO:0031400 163 0.014
b cell activation GO:0042113 161 0.014
primary mirna processing GO:0031053 1 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
hormone metabolic process GO:0042445 86 0.014
negative regulation of mrna splicing via spliceosome GO:0048025 12 0.014
protein autophosphorylation GO:0046777 61 0.014
erythrocyte differentiation GO:0030218 88 0.013
peptidyl lysine acetylation GO:0018394 45 0.013
cellular response to lipid GO:0071396 145 0.013
protein import GO:0017038 101 0.013
histone h3 acetylation GO:0043966 14 0.013
regulation of interleukin 1 alpha secretion GO:0050705 3 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
histone acetylation GO:0016573 41 0.013
muscle cell differentiation GO:0042692 261 0.013
muscle contraction GO:0006936 101 0.013
steroid metabolic process GO:0008202 119 0.013
lymphocyte differentiation GO:0030098 242 0.013
male gamete generation GO:0048232 285 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
gtp metabolic process GO:0046039 144 0.013
positive regulation of defense response GO:0031349 124 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
cell growth GO:0016049 130 0.013
intracellular protein transport GO:0006886 204 0.013
intracellular mrna localization GO:0008298 4 0.012
ncrna processing GO:0034470 26 0.012
gtp catabolic process GO:0006184 143 0.012
female sex differentiation GO:0046660 84 0.012
neuronal action potential GO:0019228 54 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
positive regulation of cell development GO:0010720 237 0.012
snrna metabolic process GO:0016073 1 0.012
cellular homeostasis GO:0019725 240 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.012
chromatin organization GO:0006325 206 0.012
developmental maturation GO:0021700 193 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
regulation of system process GO:0044057 200 0.012
response to heat GO:0009408 27 0.012
positive regulation of organelle organization GO:0010638 128 0.012
protein localization to organelle GO:0033365 185 0.012
cell junction organization GO:0034330 77 0.012
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.012
negative regulation of rna splicing GO:0033119 12 0.012
nucleotide metabolic process GO:0009117 332 0.012
meiotic nuclear division GO:0007126 115 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
glucose homeostasis GO:0042593 128 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
cellular response to external stimulus GO:0071496 88 0.011
cation transport GO:0006812 399 0.011
compound eye development GO:0048749 1 0.011
angiogenesis GO:0001525 201 0.011
peptidyl lysine methylation GO:0018022 29 0.011
muscle tissue development GO:0060537 308 0.011
regulation of response to wounding GO:1903034 189 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of cytokine production GO:0001817 266 0.011
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
organelle assembly GO:0070925 177 0.011
lung morphogenesis GO:0060425 50 0.011
peptidyl serine phosphorylation GO:0018105 74 0.011
nuclear import GO:0051170 95 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
regulation of chromatin organization GO:1902275 57 0.011
regulation of cell division GO:0051302 76 0.011
peptidyl serine modification GO:0018209 83 0.011
response to organic cyclic compound GO:0014070 198 0.011
cell maturation GO:0048469 127 0.010
histone h3 k4 trimethylation GO:0080182 5 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
protein localization to membrane GO:0072657 108 0.010
protein maturation GO:0051604 176 0.010
histone modification GO:0016570 159 0.010
divalent inorganic cation transport GO:0072511 178 0.010
blood vessel morphogenesis GO:0048514 285 0.010
ribose phosphate metabolic process GO:0019693 291 0.010
cellular chemical homeostasis GO:0055082 215 0.010
alcohol metabolic process GO:0006066 116 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
formation of primary germ layer GO:0001704 77 0.010
regulation of protein localization GO:0032880 231 0.010
positive regulation of nervous system development GO:0051962 221 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
development of primary male sexual characteristics GO:0046546 88 0.010
response to organonitrogen compound GO:0010243 246 0.010
protein catabolic process GO:0030163 221 0.010

Akap8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
musculoskeletal system disease DOID:17 0 0.024
muscular disease DOID:0080000 0 0.017
nervous system disease DOID:863 0 0.016
motor neuron disease DOID:231 0 0.015
amyotrophic lateral sclerosis DOID:332 0 0.015
neurodegenerative disease DOID:1289 0 0.015
central nervous system disease DOID:331 0 0.015
muscle tissue disease DOID:66 0 0.014
myopathy DOID:423 0 0.014