Mus musculus

116 known processes

Alx4

aristaless-like homeobox 4

(Aliases: lst)

Alx4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 337 1.000
retinal bipolar neuron differentiation GO:0060040 5 0.999
Mouse
limb development GO:0060173 166 0.999
embryonic limb morphogenesis GO:0030326 126 0.998
stem cell development GO:0048864 219 0.998
Mouse
limb morphogenesis GO:0035108 149 0.998
endodermal cell fate commitment GO:0001711 12 0.998
appendage morphogenesis GO:0035107 149 0.998
stem cell differentiation GO:0048863 268 0.997
Mouse
cell fate commitment GO:0045165 210 0.996
Mouse Worm
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.995
negative regulation of cell fate specification GO:0009996 4 0.995
cell fate specification GO:0001708 72 0.995
Worm
skeletal system development GO:0001501 356 0.995
globus pallidus development GO:0021759 2 0.993
Mouse
neural tube development GO:0021915 160 0.992
Mouse
digestive tract development GO:0048565 190 0.989
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.988
lens morphogenesis in camera type eye GO:0002089 24 0.988
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.988
Mouse
appendage development GO:0048736 166 0.984
bmp signaling pathway GO:0030509 93 0.983
neural tube patterning GO:0021532 43 0.983
embryonic organ morphogenesis GO:0048562 276 0.982
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.981
Mouse
forebrain development GO:0030900 302 0.981
Mouse
embryonic skeletal system development GO:0048706 120 0.981
developmental induction GO:0031128 34 0.980
mesodermal cell fate commitment GO:0001710 17 0.978
endodermal cell fate specification GO:0001714 4 0.977
gastrulation GO:0007369 116 0.975
regulation of bmp signaling pathway GO:0030510 60 0.974
formation of primary germ layer GO:0001704 77 0.973
olfactory bulb interneuron development GO:0021891 7 0.970
Mouse
forebrain morphogenesis GO:0048853 17 0.970
negative regulation of gastrulation GO:2000542 3 0.969
forebrain neuron differentiation GO:0021879 52 0.968
Mouse
stem cell maintenance GO:0019827 130 0.968
camera type eye development GO:0043010 266 0.968
Mouse
pituitary gland development GO:0021983 38 0.967
digestive tract morphogenesis GO:0048546 147 0.966
cell cell signaling involved in cell fate commitment GO:0045168 35 0.966
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.965
prostate gland morphogenesis GO:0060512 32 0.961
axon guidance GO:0007411 141 0.961
Mouse
olfactory bulb interneuron differentiation GO:0021889 12 0.958
Mouse
astrocyte fate commitment GO:0060018 4 0.957
skeletal system morphogenesis GO:0048705 203 0.955
branching involved in ureteric bud morphogenesis GO:0001658 56 0.954
renal vesicle induction GO:0072034 3 0.953
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.949
mesenchymal cell development GO:0014031 93 0.948
Mouse
diencephalon development GO:0021536 63 0.946
Mouse
epithelial to mesenchymal transition GO:0001837 47 0.945
neuron projection guidance GO:0097485 141 0.940
Mouse
forebrain generation of neurons GO:0021872 63 0.940
Mouse
positive regulation of apoptotic process GO:0043065 217 0.937
adenohypophysis development GO:0021984 14 0.937
limbic system development GO:0021761 72 0.934
ear development GO:0043583 200 0.933
leukocyte differentiation GO:0002521 342 0.931
tube formation GO:0035148 140 0.930
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.927
organ induction GO:0001759 21 0.926
regulation of asymmetric cell division GO:0009786 4 0.922
retina development in camera type eye GO:0060041 119 0.921
Mouse
mesoderm morphogenesis GO:0048332 64 0.918
telencephalon development GO:0021537 186 0.917
Mouse
regulation of endodermal cell fate specification GO:0042663 2 0.915
mesenchyme development GO:0060485 152 0.915
Mouse
mesenchymal cell proliferation GO:0010463 44 0.913
trophectodermal cell differentiation GO:0001829 21 0.912
pallium development GO:0021543 120 0.910
Mouse
somatic stem cell maintenance GO:0035019 47 0.908
cochlea morphogenesis GO:0090103 22 0.907
noradrenergic neuron differentiation GO:0003357 6 0.905
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.904
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.904
sensory organ morphogenesis GO:0090596 242 0.902
Mouse
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.899
negative regulation of prostatic bud formation GO:0060686 4 0.898
cell maturation GO:0048469 127 0.897
Mouse
embryonic hindlimb morphogenesis GO:0035116 32 0.896
regulation of organ morphogenesis GO:2000027 144 0.896
epithelial tube morphogenesis GO:0060562 303 0.895
Mouse
corticotropin hormone secreting cell differentiation GO:0060128 3 0.895
mesoderm formation GO:0001707 62 0.894
endoderm formation GO:0001706 20 0.893
renal tubule development GO:0061326 87 0.893
metanephric nephron tubule formation GO:0072289 4 0.891
closure of optic fissure GO:0061386 2 0.891
specification of organ identity GO:0010092 30 0.891
negative regulation of epithelial cell proliferation GO:0050680 64 0.890
chondrocyte differentiation GO:0002062 72 0.889
tube closure GO:0060606 91 0.886
Mouse
positive regulation of bmp signaling pathway GO:0030513 23 0.886
chondrocyte development GO:0002063 24 0.885
heart morphogenesis GO:0003007 178 0.884
positive regulation of epithelial cell proliferation GO:0050679 68 0.884
mesoderm development GO:0007498 100 0.883
regulation of chondrocyte differentiation GO:0032330 33 0.881
embryonic appendage morphogenesis GO:0035113 126 0.877
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.876
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.876
epithelial tube formation GO:0072175 130 0.875
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.873
Mouse
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.871
cell differentiation in spinal cord GO:0021515 53 0.870
epithelial cell morphogenesis GO:0003382 41 0.870
cell proliferation in forebrain GO:0021846 30 0.868
Mouse
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.866
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.865
blastocyst formation GO:0001825 33 0.864
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.863
regulation of mesenchymal cell apoptotic process GO:2001053 14 0.860
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.858
endocrine system development GO:0035270 98 0.853
trachea cartilage morphogenesis GO:0060535 4 0.853
regulation of cardiac cell fate specification GO:2000043 1 0.852
blastocyst development GO:0001824 80 0.851
regulation of cell cycle GO:0051726 281 0.846
neuron projection extension GO:1990138 64 0.845
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.844
astrocyte differentiation GO:0048708 43 0.842
paraxial mesodermal cell fate commitment GO:0048343 2 0.841
kidney epithelium development GO:0072073 121 0.841
chemotaxis GO:0006935 247 0.841
Mouse
embryonic epithelial tube formation GO:0001838 130 0.840
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.840
hypophysis morphogenesis GO:0048850 3 0.837
primary neural tube formation GO:0014020 95 0.834
Mouse
epithelial cell development GO:0002064 159 0.833
neural tube formation GO:0001841 108 0.830
Mouse
organ growth GO:0035265 117 0.828
Mouse
positive regulation of programmed cell death GO:0043068 218 0.828
ear morphogenesis GO:0042471 118 0.821
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.821
brain morphogenesis GO:0048854 32 0.820
palate development GO:0060021 76 0.820
central nervous system neuron differentiation GO:0021953 162 0.820
Mouse
digestive system development GO:0055123 200 0.807
neural crest cell development GO:0014032 48 0.799
lymphocyte differentiation GO:0030098 242 0.797
cardiac chamber morphogenesis GO:0003206 93 0.792
developmental maturation GO:0021700 193 0.788
Mouse
cerebral cortex development GO:0021987 86 0.788
Mouse
regulation of transcription involved in cell fate commitment GO:0060850 15 0.784
positive regulation of stem cell proliferation GO:2000648 59 0.783
paraxial mesodermal cell differentiation GO:0048342 2 0.782
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.779
embryonic placenta development GO:0001892 98 0.777
fat cell differentiation GO:0045444 160 0.775
spinal cord motor neuron differentiation GO:0021522 35 0.775
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.772
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.769
negative regulation of cell development GO:0010721 169 0.768
epithelial cell fate commitment GO:0072148 13 0.767
Mouse
cell division GO:0051301 120 0.767
auditory receptor cell fate determination GO:0042668 3 0.767
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.766
axis elongation involved in somitogenesis GO:0090245 4 0.762
pancreatic pp cell fate commitment GO:0003329 2 0.759
rostrocaudal neural tube patterning GO:0021903 12 0.757
regulation of mesenchymal cell proliferation GO:0010464 37 0.755
negative regulation of neuron differentiation GO:0045665 101 0.755
forebrain regionalization GO:0021871 25 0.754
skeletal muscle cell differentiation GO:0035914 66 0.753
mesonephros development GO:0001823 97 0.745
embryonic digit morphogenesis GO:0042733 56 0.744
diencephalon morphogenesis GO:0048852 6 0.744
odontogenesis GO:0042476 78 0.742
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.738
Mouse
cell proliferation in external granule layer GO:0021924 10 0.736
hematopoietic progenitor cell differentiation GO:0002244 143 0.736
embryonic skeletal system morphogenesis GO:0048704 91 0.735
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.733
axis elongation GO:0003401 30 0.730
nephron tubule morphogenesis GO:0072078 68 0.728
mesodermal cell differentiation GO:0048333 22 0.727
hair follicle development GO:0001942 85 0.726
Human
lung induction GO:0060492 3 0.726
axial mesodermal cell fate commitment GO:0048322 1 0.723
neuroendocrine cell differentiation GO:0061101 7 0.722
lung morphogenesis GO:0060425 50 0.721
ascending aorta morphogenesis GO:0035910 3 0.720
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.719
embryonic forelimb morphogenesis GO:0035115 32 0.719
negative regulation of chondrocyte differentiation GO:0032331 13 0.719
liver development GO:0001889 66 0.719
cardiac septum development GO:0003279 59 0.716
prostate gland epithelium morphogenesis GO:0060740 31 0.714
positive regulation of wnt signaling pathway GO:0030177 45 0.713
somatotropin secreting cell differentiation GO:0060126 4 0.712
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.706
neural tube closure GO:0001843 90 0.703
Mouse
urogenital system development GO:0001655 261 0.703
oligodendrocyte differentiation GO:0048709 53 0.699
hindlimb morphogenesis GO:0035137 42 0.692
inner cell mass cell differentiation GO:0001826 7 0.688
somitogenesis GO:0001756 69 0.687
midbrain hindbrain boundary maturation GO:0021732 1 0.686
regulation of cell division GO:0051302 76 0.685
neural crest cell migration GO:0001755 32 0.684
nephron tubule development GO:0072080 84 0.684
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.683
positive regulation of chondrocyte differentiation GO:0032332 13 0.679
renal system development GO:0072001 225 0.675
nephron tubule formation GO:0072079 20 0.668
determination of heart left right asymmetry GO:0061371 48 0.664
morphogenesis of a branching epithelium GO:0061138 193 0.663
positive regulation of mesenchymal cell apoptotic process GO:2001055 3 0.663
cell fate determination GO:0001709 32 0.663
gland development GO:0048732 330 0.658
respiratory system development GO:0060541 190 0.657
regulation of heart morphogenesis GO:2000826 22 0.655
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.654
glial cell differentiation GO:0010001 131 0.652
embryonic nail plate morphogenesis GO:0035880 3 0.649
neuroepithelial cell differentiation GO:0060563 37 0.648
skin development GO:0043588 220 0.643
Human
cardiocyte differentiation GO:0035051 87 0.642
cardiac muscle tissue growth GO:0055017 37 0.642
endoderm development GO:0007492 45 0.639
central nervous system neuron development GO:0021954 67 0.638
Mouse
cerebellum formation GO:0021588 1 0.638
pyramidal neuron migration GO:0021852 1 0.635
apoptotic process involved in morphogenesis GO:0060561 25 0.634
head morphogenesis GO:0060323 34 0.629
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.628
mesonephric duct morphogenesis GO:0072180 4 0.627
mammary gland morphogenesis GO:0060443 54 0.621
inner ear morphogenesis GO:0042472 101 0.619
glial cell development GO:0021782 54 0.617
kidney development GO:0001822 213 0.615
negative regulation of mesenchymal cell apoptotic process GO:2001054 11 0.614
retinal ganglion cell axon guidance GO:0031290 18 0.611
regulation of muscle tissue development GO:1901861 97 0.611
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.610
wound healing GO:0042060 157 0.609
primary prostatic bud elongation GO:0060516 2 0.607
cell adhesion GO:0007155 329 0.606
regulation of cardioblast differentiation GO:0051890 3 0.606
inner ear receptor cell differentiation GO:0060113 61 0.605
cardiac cell fate specification GO:0060912 2 0.603
lung development GO:0030324 164 0.602
cardiac cell fate commitment GO:0060911 10 0.602
endocardial cushion morphogenesis GO:0003203 18 0.601
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.599
kidney morphogenesis GO:0060993 83 0.592
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.588
mesenchymal cell differentiation GO:0048762 107 0.586
Mouse
endodermal cell fate determination GO:0007493 2 0.581
tooth mineralization GO:0034505 9 0.578
otic placode formation GO:0043049 1 0.576
axonogenesis GO:0007409 274 0.575
Mouse
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.573
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.573
gabaergic neuron differentiation GO:0097154 11 0.571
Mouse
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.570
regulation of morphogenesis of a branching structure GO:0060688 53 0.567
labyrinthine layer development GO:0060711 49 0.566
metanephric capsule specification GO:0072267 1 0.557
regulation of lens epithelial cell proliferation GO:2001109 1 0.557
locus ceruleus development GO:0021703 1 0.556
developmental growth involved in morphogenesis GO:0060560 138 0.556
epithelial cell proliferation involved in prostatic bud elongation GO:0060517 1 0.556
telencephalon regionalization GO:0021978 14 0.555
left lung development GO:0060459 4 0.554
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.553
endochondral bone morphogenesis GO:0060350 50 0.551
spemann organizer formation GO:0060061 2 0.550
regulation of ketone biosynthetic process GO:0010566 2 0.548
ureteric bud development GO:0001657 94 0.547
odontogenesis of dentin containing tooth GO:0042475 66 0.547
cardiac atrium development GO:0003230 24 0.546
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.546
nephric duct formation GO:0072179 4 0.544
olfactory lobe development GO:0021988 32 0.544
Mouse
bone development GO:0060348 120 0.544
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.541
glial cell fate commitment GO:0021781 14 0.540
cerebral cortex gabaergic interneuron development GO:0021894 6 0.539
Mouse
ureteric bud morphogenesis GO:0060675 62 0.537
germ cell development GO:0007281 185 0.536
nose development GO:0043584 12 0.535
regulation of stem cell differentiation GO:2000736 50 0.533
enteric nervous system development GO:0048484 11 0.530
regulation of cardiac muscle tissue development GO:0055024 31 0.528
negative regulation of nervous system development GO:0051961 156 0.524
regulation of cartilage development GO:0061035 44 0.523
negative regulation of gliogenesis GO:0014014 23 0.523
regulation of gastrulation GO:0010470 16 0.522
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.519
cardiac septum morphogenesis GO:0060411 46 0.517
negative regulation of glial cell proliferation GO:0060253 4 0.516
cartilage condensation GO:0001502 18 0.513
telencephalon cell migration GO:0022029 55 0.511
Mouse
regulation of osteoblast differentiation GO:0045667 67 0.510
nephron morphogenesis GO:0072028 69 0.508
t cell differentiation GO:0030217 174 0.506
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.503
cerebral cortex gabaergic interneuron fate commitment GO:0021893 2 0.502
embryonic heart tube formation GO:0003144 1 0.500
biomineral tissue development GO:0031214 64 0.500
endodermal cell differentiation GO:0035987 14 0.500
morphogenesis of a branching structure GO:0001763 203 0.499
epithelial tube branching involved in lung morphogenesis GO:0060441 28 0.497
salivary gland morphogenesis GO:0007435 33 0.496
placenta development GO:0001890 140 0.496
hypothalamus development GO:0021854 16 0.495
neuron fate specification GO:0048665 30 0.494
prostatic bud formation GO:0060513 10 0.494
regulation of glial cell differentiation GO:0045685 41 0.493
septum primum development GO:0003284 4 0.493
cardiac atrium morphogenesis GO:0003209 23 0.490
regulation of cell fate commitment GO:0010453 19 0.489
embryonic heart tube development GO:0035050 65 0.487
regulation of cell fate specification GO:0042659 10 0.486
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.485
dorsal ventral neural tube patterning GO:0021904 28 0.485
metanephros morphogenesis GO:0003338 24 0.484
semicircular canal formation GO:0060876 1 0.483
positive regulation of cartilage development GO:0061036 18 0.482
cerebral cortex cell migration GO:0021795 44 0.481
Mouse
positive regulation of striated muscle tissue development GO:0045844 31 0.480
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.477
cellular chemical homeostasis GO:0055082 215 0.476
nephron epithelium morphogenesis GO:0072088 68 0.475
nephron development GO:0072006 109 0.475
specification of organ position GO:0010159 3 0.475
stem cell fate specification GO:0048866 3 0.473
atrial septum morphogenesis GO:0060413 11 0.470
exocrine system development GO:0035272 45 0.470
positive regulation of cell death GO:0010942 224 0.469
mesenchymal cell differentiation involved in lung development GO:0060915 2 0.467
metanephros development GO:0001656 79 0.463
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.459
cell differentiation in hindbrain GO:0021533 24 0.456
positive regulation of growth GO:0045927 104 0.455
Mouse
positive regulation of cell development GO:0010720 237 0.454
hepaticobiliary system development GO:0061008 67 0.452
positive regulation of transcription via serum response element binding GO:0010735 1 0.450
regulation of wnt signaling pathway GO:0030111 123 0.449
regulation of astrocyte differentiation GO:0048710 20 0.449
embryonic skeletal joint development GO:0072498 13 0.448
embryonic camera type eye development GO:0031076 36 0.447
ectoderm formation GO:0001705 3 0.446
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.443
forelimb morphogenesis GO:0035136 40 0.442
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.442
cochlea development GO:0090102 35 0.442
negative regulation of mesodermal cell fate specification GO:0042662 3 0.441
positive regulation of osteoblast differentiation GO:0045669 34 0.441
segmentation GO:0035282 93 0.439
cardiac ventricle formation GO:0003211 8 0.439
regulation of endodermal cell differentiation GO:1903224 2 0.436
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 9 0.434
olfactory bulb development GO:0021772 30 0.434
Mouse
regulation of ossification GO:0030278 112 0.431
hair cycle GO:0042633 90 0.431
Human
positive regulation of ossification GO:0045778 47 0.431
regulation of odontogenesis GO:0042481 18 0.427
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.424
regulation of apoptotic process involved in morphogenesis GO:1902337 10 0.424
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.424
outflow tract morphogenesis GO:0003151 53 0.422
apoptotic process involved in development GO:1902742 28 0.420
striated muscle cell proliferation GO:0014855 39 0.420
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.419
mitral valve morphogenesis GO:0003183 4 0.419
positive regulation of gliogenesis GO:0014015 27 0.418
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.417
mitral valve development GO:0003174 4 0.416
bone morphogenesis GO:0060349 78 0.416
positive regulation of neuron differentiation GO:0045666 141 0.416
pericardium development GO:0060039 16 0.415
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.414
cardiac chamber development GO:0003205 108 0.412
hindbrain formation GO:0021576 1 0.411
hindbrain development GO:0030902 128 0.405
negative regulation of stem cell maintenance GO:1902455 4 0.404
positive regulation of cell cycle GO:0045787 92 0.404
eye photoreceptor cell differentiation GO:0001754 41 0.402
endocardial cell differentiation GO:0060956 4 0.401
cerebral cortex radially oriented cell migration GO:0021799 31 0.398
endothelial cell differentiation GO:0045446 41 0.398
forebrain cell migration GO:0021885 58 0.397
Mouse
regulation of cardiac muscle cell proliferation GO:0060043 23 0.397
negative regulation of endodermal cell differentiation GO:1903225 1 0.393
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.392
trophectodermal cellular morphogenesis GO:0001831 3 0.392
regulation of cell activation GO:0050865 289 0.391
regulation of fat cell differentiation GO:0045598 81 0.391
trachea formation GO:0060440 3 0.389
cerebral cortex neuron differentiation GO:0021895 19 0.388
Mouse
mesenchymal to epithelial transition GO:0060231 12 0.387
metanephric dct cell differentiation GO:0072240 3 0.387
positive regulation of muscle tissue development GO:1901863 32 0.387
heart field specification GO:0003128 6 0.386
metanephric nephron morphogenesis GO:0072273 19 0.385
central nervous system vasculogenesis GO:0022009 3 0.384
ossification GO:0001503 216 0.384
regulation of mesodermal cell fate specification GO:0042661 5 0.383
optic vesicle morphogenesis GO:0003404 2 0.380
mesonephric epithelium development GO:0072163 94 0.379
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.376
negative regulation of growth GO:0045926 99 0.375
morphogenesis of an epithelial fold GO:0060571 28 0.375
retina morphogenesis in camera type eye GO:0060042 45 0.372
Mouse
axon extension involved in axon guidance GO:0048846 14 0.371
determination of left right symmetry GO:0007368 80 0.369
positive regulation of meiosis GO:0045836 14 0.367
regulation of embryonic development GO:0045995 71 0.366
regulation of kidney development GO:0090183 40 0.365
regulation of gliogenesis GO:0014013 50 0.364
forebrain neuron fate commitment GO:0021877 13 0.359
branch elongation of an epithelium GO:0060602 19 0.357
regulation of organ growth GO:0046620 61 0.357
Mouse
regulation of bone mineralization GO:0030500 31 0.357
positive regulation of apoptotic signaling pathway GO:2001235 95 0.356
muscle tissue development GO:0060537 308 0.355
embryonic eye morphogenesis GO:0048048 29 0.355
mesodermal cell fate specification GO:0007501 11 0.354
cell type specific apoptotic process GO:0097285 268 0.352
central nervous system morphogenesis GO:0021551 2 0.351
multi organism reproductive behavior GO:0044705 29 0.351
Worm
cellular response to growth factor stimulus GO:0071363 197 0.351
bmp signaling pathway involved in heart development GO:0061312 2 0.349
regulation of transcription from rna polymerase ii promoter involved in forebrain neuron fate commitment GO:0021882 3 0.346
activation of meiosis GO:0090427 4 0.346
positive regulation of tendon cell differentiation GO:2001051 1 0.345
primitive streak formation GO:0090009 10 0.344
cellular response to lipid GO:0071396 145 0.344
nail development GO:0035878 5 0.344
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.343
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.343
oogenesis GO:0048477 56 0.339
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.338
positive regulation of kidney development GO:0090184 28 0.338
interneuron migration from the subpallium to the cortex GO:0021830 7 0.338
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.337
cell migration involved in gastrulation GO:0042074 13 0.336
male sex differentiation GO:0046661 109 0.335
inner cell mass cellular morphogenesis GO:0001828 1 0.335
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.334
salivary gland development GO:0007431 37 0.332
positive regulation of cardioblast differentiation GO:0051891 3 0.330
immune effector process GO:0002252 321 0.329
hypothalamus cell differentiation GO:0021979 8 0.328
stem cell proliferation GO:0072089 117 0.326
hemangioblast cell differentiation GO:0060217 1 0.323
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 2 0.323
artery development GO:0060840 53 0.321
connective tissue development GO:0061448 179 0.319
axial mesodermal cell fate specification GO:0048327 1 0.319
epidermis development GO:0008544 187 0.318
Human
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.317
gliogenesis GO:0042063 141 0.317
striated muscle tissue development GO:0014706 293 0.316
neural crest cell differentiation GO:0014033 54 0.315
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.315
his purkinje system cell differentiation GO:0060932 2 0.314
establishment of neuroblast polarity GO:0045200 1 0.314
negative regulation of apoptotic process involved in morphogenesis GO:1902338 6 0.309
aorta morphogenesis GO:0035909 22 0.308
cardiac right atrium morphogenesis GO:0003213 3 0.308
craniofacial suture morphogenesis GO:0097094 10 0.307
single organismal cell cell adhesion GO:0016337 131 0.307
mammary gland bud formation GO:0060615 2 0.305
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.304
regulation of neuroblast proliferation GO:1902692 27 0.303
regulation of lymphocyte activation GO:0051249 240 0.303
visual perception GO:0007601 52 0.301
Mouse
ventricular septum morphogenesis GO:0060412 27 0.300
submandibular salivary gland formation GO:0060661 1 0.299
endocrine pancreas development GO:0031018 29 0.299
roof plate formation GO:0021509 1 0.299
cell growth GO:0016049 130 0.298
regulation of cell cycle process GO:0010564 160 0.298
production of molecular mediator of immune response GO:0002440 103 0.298
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.297
negative regulation of neuron projection development GO:0010977 50 0.296
forebrain neuron development GO:0021884 30 0.296
Mouse
ectodermal placode formation GO:0060788 16 0.296
response to acid chemical GO:0001101 111 0.294
somite development GO:0061053 81 0.294
ventricular cardiac myofibril assembly GO:0055005 3 0.293
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.292
osteoblast development GO:0002076 17 0.291
commitment of multipotent stem cells to neuronal lineage in forebrain GO:0021898 3 0.291
regulation of smoothened signaling pathway GO:0008589 58 0.290
metanephric nephron development GO:0072210 34 0.289
cranial suture morphogenesis GO:0060363 8 0.289
neural retina development GO:0003407 41 0.289
Mouse
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.288
metanephric nephron epithelium development GO:0072243 19 0.285
ureter smooth muscle development GO:0072191 5 0.283
digestion GO:0007586 40 0.283
Mouse
somite rostral caudal axis specification GO:0032525 13 0.283
hindbrain tangential cell migration GO:0021934 2 0.282

Alx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org