Mus musculus

89 known processes

En2

engrailed 2

(Aliases: BB131122,En-2)

En2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuroblast fate determination GO:0007400 1 0.931
Fly
central nervous system neuron differentiation GO:0021953 162 0.894
Fly
anterior commissure morphogenesis GO:0021960 6 0.872
Fly
neuroblast differentiation GO:0014016 2 0.859
Fly
spinal cord development GO:0021510 81 0.828
nerve development GO:0021675 67 0.822
mesenchyme development GO:0060485 152 0.809
bmp signaling pathway GO:0030509 93 0.800
motor neuron migration GO:0097475 4 0.796
fourth ventricle development GO:0021592 2 0.792
innervation GO:0060384 22 0.755
auditory receptor cell fate determination GO:0042668 3 0.749
stem cell differentiation GO:0048863 268 0.736
Fly
forebrain development GO:0030900 302 0.720
Fly
digestive system development GO:0055123 200 0.720
regulation of bmp signaling pathway GO:0030510 60 0.717
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.707
Zebrafish
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.686
stem cell development GO:0048864 219 0.673
synaptic transmission GO:0007268 329 0.668
formation of primary germ layer GO:0001704 77 0.646
retina development in camera type eye GO:0060041 119 0.641
embryonic organ morphogenesis GO:0048562 276 0.630
retinal ganglion cell axon guidance GO:0031290 18 0.625
glial cell differentiation GO:0010001 131 0.621
endodermal cell fate specification GO:0001714 4 0.609
regulation of neuron differentiation GO:0045664 281 0.600
regulation of neuron projection development GO:0010975 169 0.600
lateral motor column neuron migration GO:0097477 3 0.591
positive regulation of nervous system development GO:0051962 221 0.584
spinal cord motor neuron migration GO:0097476 4 0.576
positive regulation of bmp signaling pathway GO:0030513 23 0.572
eye photoreceptor cell differentiation GO:0001754 41 0.566
cellular amino acid metabolic process GO:0006520 103 0.562
peripheral nervous system neuron axonogenesis GO:0048936 3 0.557
regionalization GO:0003002 337 0.546
Zebrafish Mouse Fly
appendage morphogenesis GO:0035107 149 0.514
Mouse Fly
neuroblast fate commitment GO:0014017 1 0.506
Fly
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.505
digestive tract development GO:0048565 190 0.492
appendage development GO:0048736 166 0.487
Mouse Fly
endodermal cell fate commitment GO:0001711 12 0.483
ventral midline development GO:0007418 4 0.483
Fly
gastrulation GO:0007369 116 0.471
spinal cord motor neuron differentiation GO:0021522 35 0.468
cell fate determination GO:0001709 32 0.458
Fly
epithelial cell development GO:0002064 159 0.449
sensory organ morphogenesis GO:0090596 242 0.422
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.419
cerebellum development GO:0021549 77 0.418
positive regulation of neuron differentiation GO:0045666 141 0.418
camera type eye development GO:0043010 266 0.415
cell fate commitment GO:0045165 210 0.414
Zebrafish Worm Fly
inner ear receptor cell differentiation GO:0060113 61 0.413
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.411
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.409
cardiac chamber morphogenesis GO:0003206 93 0.397
embryonic heart tube morphogenesis GO:0003143 51 0.395
blastocyst formation GO:0001825 33 0.391
ear morphogenesis GO:0042471 118 0.387
cell fate specification GO:0001708 72 0.367
Zebrafish Worm
epidermis development GO:0008544 187 0.363
Worm
pituitary gland development GO:0021983 38 0.361
regulation of cellular amine metabolic process GO:0033238 20 0.358
determination of left right asymmetry in nervous system GO:0035545 1 0.354
forebrain generation of neurons GO:0021872 63 0.347
neuron fate specification GO:0048665 30 0.333
hematopoietic progenitor cell differentiation GO:0002244 143 0.331
morphogenesis of embryonic epithelium GO:0016331 159 0.325
retina morphogenesis in camera type eye GO:0060042 45 0.320
ear development GO:0043583 200 0.317
endoderm development GO:0007492 45 0.317
primary neural tube formation GO:0014020 95 0.314
astrocyte differentiation GO:0048708 43 0.311
visceral motor neuron differentiation GO:0021524 3 0.311
acetylcholine secretion neurotransmission GO:0014055 2 0.310
neural tube closure GO:0001843 90 0.308
renal system development GO:0072001 225 0.306
neuron projection guidance GO:0097485 141 0.303
Fly
neuron projection extension GO:1990138 64 0.300
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.300
diencephalon development GO:0021536 63 0.298
negative regulation of neuron differentiation GO:0045665 101 0.297
axonogenesis GO:0007409 274 0.297
Fly
organelle fission GO:0048285 170 0.296
inner ear morphogenesis GO:0042472 101 0.295
negative regulation of cell development GO:0010721 169 0.293
glial cell development GO:0021782 54 0.291
brain morphogenesis GO:0048854 32 0.289
stem cell maintenance GO:0019827 130 0.288
positive regulation of rhodopsin gene expression GO:0045872 2 0.286
muscle cell differentiation GO:0042692 261 0.286
adult walking behavior GO:0007628 41 0.285
pallium development GO:0021543 120 0.283
cell proliferation in forebrain GO:0021846 30 0.283
gland development GO:0048732 330 0.283
ectoderm formation GO:0001705 3 0.283
cell differentiation in hindbrain GO:0021533 24 0.282
peptidyl tyrosine modification GO:0018212 145 0.278
regulation of stem cell differentiation GO:2000736 50 0.275
central nervous system projection neuron axonogenesis GO:0021952 21 0.272
Fly
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.272
kidney development GO:0001822 213 0.271
photoreceptor cell differentiation GO:0046530 52 0.271
compartment pattern specification GO:0007386 4 0.270
Fly
neural tube formation GO:0001841 108 0.268
cerebellum morphogenesis GO:0021587 42 0.262
oviduct epithelium development GO:0035846 1 0.257
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.256
cell differentiation in spinal cord GO:0021515 53 0.253
mesenchymal cell development GO:0014031 93 0.250
hindbrain morphogenesis GO:0021575 46 0.248
mechanoreceptor differentiation GO:0042490 67 0.246
thick ascending limb development GO:0072023 2 0.243
cell division GO:0051301 120 0.243
cell proliferation in hindbrain GO:0021534 10 0.241
midbrain hindbrain boundary development GO:0030917 9 0.239
Zebrafish Mouse
mesoderm development GO:0007498 100 0.239
negative regulation of neuron death GO:1901215 98 0.239
regulation of cellular ketone metabolic process GO:0010565 66 0.236
neural tube development GO:0021915 160 0.235
Zebrafish Mouse
inner ear receptor cell development GO:0060119 39 0.235
epithelial to mesenchymal transition GO:0001837 47 0.235
forebrain neuron differentiation GO:0021879 52 0.235
ventral spinal cord development GO:0021517 48 0.234
myelination in peripheral nervous system GO:0022011 19 0.234
hindbrain development GO:0030902 128 0.233
urogenital system development GO:0001655 261 0.232
metanephric dct cell differentiation GO:0072240 3 0.231
cerebellar cortex formation GO:0021697 22 0.230
mitral valve morphogenesis GO:0003183 4 0.227
glycosyl compound catabolic process GO:1901658 206 0.226
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.226
forebrain neuron fate commitment GO:0021877 13 0.220
regulation of chondrocyte differentiation GO:0032330 33 0.215
regulation of neuron death GO:1901214 134 0.214
metanephric loop of henle development GO:0072236 4 0.214
neural crest cell migration GO:0001755 32 0.214
heart morphogenesis GO:0003007 178 0.213
neuron apoptotic process GO:0051402 142 0.212
cardiac septum morphogenesis GO:0060411 46 0.210
erk1 and erk2 cascade GO:0070371 77 0.209
midbrain development GO:0030901 35 0.208
determination of left right symmetry GO:0007368 80 0.208
auditory receptor cell fate specification GO:0042667 1 0.207
developmental cell growth GO:0048588 84 0.206
positive regulation of organelle organization GO:0010638 128 0.205
positive regulation of cellular amine metabolic process GO:0033240 5 0.201
ventral spinal cord interneuron differentiation GO:0021514 16 0.199
corticotropin hormone secreting cell differentiation GO:0060128 3 0.199
ion transmembrane transport GO:0034220 361 0.198
dentate gyrus development GO:0021542 14 0.194
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.193
embryonic eye morphogenesis GO:0048048 29 0.191
axon guidance GO:0007411 141 0.191
Fly
rostrocaudal neural tube patterning GO:0021903 12 0.190
Zebrafish Mouse
ventricular septum morphogenesis GO:0060412 27 0.189
amine metabolic process GO:0009308 45 0.186
eye photoreceptor cell development GO:0042462 31 0.186
stem cell fate determination GO:0048867 2 0.186
Fly
regulation of cardiac cell fate specification GO:2000043 1 0.185
positive regulation of nephron tubule epithelial cell differentiation GO:2000768 1 0.184
metencephalon development GO:0022037 89 0.184
developmental maturation GO:0021700 193 0.184
chemotaxis GO:0006935 247 0.184
Fly
cardiac ventricle morphogenesis GO:0003208 50 0.184
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.183
action potential GO:0001508 78 0.182
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.181
cell differentiation involved in embryonic placenta development GO:0060706 26 0.181
epithelial tube formation GO:0072175 130 0.179
forebrain regionalization GO:0021871 25 0.179
organic hydroxy compound biosynthetic process GO:1901617 77 0.178
horizontal cell localization GO:0035852 1 0.177
regulation of protein localization GO:0032880 231 0.176
regulation of cell cycle process GO:0010564 160 0.176
limbic system development GO:0021761 72 0.175
digestive tract morphogenesis GO:0048546 147 0.173
regulation of neuron apoptotic process GO:0043523 122 0.172
dendrite development GO:0016358 115 0.171
embryonic retina morphogenesis in camera type eye GO:0060059 7 0.168
positive regulation of stress activated mapk cascade GO:0032874 48 0.164
positive regulation of neuron projection development GO:0010976 79 0.164
gonad morphogenesis GO:0035262 1 0.162
cellular amine metabolic process GO:0044106 44 0.161
determination of heart left right asymmetry GO:0061371 48 0.160
defecation GO:0030421 1 0.160
pancreatic a cell fate commitment GO:0003326 2 0.159
regulation of cellular amino acid metabolic process GO:0006521 5 0.159
gamma aminobutyric acid signaling pathway GO:0007214 8 0.158
cartilage development GO:0051216 140 0.156
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.156
trophectodermal cell differentiation GO:0001829 21 0.156
mapk cascade GO:0000165 281 0.156
chloride transport GO:0006821 32 0.155
embryonic heart tube development GO:0035050 65 0.155
inorganic anion transport GO:0015698 43 0.154
cognition GO:0050890 149 0.154
cardiac epithelial to mesenchymal transition GO:0060317 18 0.152
negative regulation of nervous system development GO:0051961 156 0.152
cerebral cortex neuron differentiation GO:0021895 19 0.151
blastocyst development GO:0001824 80 0.148
hair cell differentiation GO:0035315 40 0.147
transdifferentiation GO:0060290 1 0.147
negative regulation of intracellular signal transduction GO:1902532 167 0.146
regulation of nuclear division GO:0051783 56 0.146
regulation of cell division GO:0051302 76 0.146
embryonic heart tube formation GO:0003144 1 0.145
negative regulation of neuron projection development GO:0010977 50 0.145
cochlea development GO:0090102 35 0.144
cardiac chamber development GO:0003205 108 0.144
cardiac atrium development GO:0003230 24 0.142
telencephalon development GO:0021537 186 0.142
Fly
cellular response to growth factor stimulus GO:0071363 197 0.142
hemangioblast cell differentiation GO:0060217 1 0.141
cerebellar cortex development GO:0021695 48 0.141
mesoderm formation GO:0001707 62 0.141
cerebellar granule cell precursor proliferation GO:0021930 10 0.140
cellular response to histamine GO:0071420 1 0.139
sensory neuron axon guidance GO:0097374 3 0.138
pancreatic pp cell fate commitment GO:0003329 2 0.137
epithelial cell morphogenesis GO:0003382 41 0.137
neurohypophysis development GO:0021985 2 0.136
embryonic appendage morphogenesis GO:0035113 126 0.136
Mouse
photoreceptor cell development GO:0042461 40 0.136
transmembrane transport GO:0055085 412 0.135
regulation of transmembrane transport GO:0034762 128 0.135
sensory perception of sound GO:0007605 97 0.135
regulation of axon diameter GO:0031133 6 0.134
inorganic anion transmembrane transport GO:0098661 29 0.133
spinal cord motor neuron cell fate specification GO:0021520 13 0.132
cell type specific apoptotic process GO:0097285 268 0.131
inner cell mass cell differentiation GO:0001826 7 0.131
developmental growth involved in morphogenesis GO:0060560 138 0.129
stem cell fate commitment GO:0048865 5 0.127
Fly
mesendoderm development GO:0048382 3 0.127
regulation of neural retina development GO:0061074 3 0.127
cardiac right ventricle formation GO:0003219 3 0.126
central nervous system neuron development GO:0021954 67 0.126
Fly
positive regulation of protein phosphorylation GO:0001934 242 0.125
positive regulation of glial cell proliferation GO:0060252 4 0.125
peptidyl amino acid modification GO:0018193 336 0.123
autonomic nervous system development GO:0048483 43 0.123
pancreatic pp cell differentiation GO:0003312 2 0.123
regulation of astrocyte differentiation GO:0048710 20 0.123
positive regulation of cell division GO:0051781 31 0.123
cardiac muscle cell differentiation GO:0055007 69 0.120
epithelium migration GO:0090132 63 0.120
embryonic limb morphogenesis GO:0030326 126 0.119
Mouse
regulation of rhodopsin gene expression GO:0007468 3 0.117
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.116
thermosensory behavior GO:0040040 1 0.115
mesodermal cell migration GO:0008078 4 0.115
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.115
positive regulation of protein modification process GO:0031401 299 0.115
neuron migration GO:0001764 122 0.114
closure of optic fissure GO:0061386 2 0.113
axis elongation involved in somitogenesis GO:0090245 4 0.113
regulation of mapk cascade GO:0043408 248 0.113
mesonephros development GO:0001823 97 0.112
cerebellar cortex morphogenesis GO:0021696 32 0.112
visual learning GO:0008542 44 0.111
schwann cell development GO:0014044 22 0.111
neural crest cell development GO:0014032 48 0.110
negative regulation of cell fate specification GO:0009996 4 0.110
limb development GO:0060173 166 0.110
Mouse
odontogenesis GO:0042476 78 0.109
trabecular meshwork development GO:0002930 2 0.108
hypothalamus cell differentiation GO:0021979 8 0.107
adult locomotory behavior GO:0008344 91 0.106
canonical wnt signaling pathway GO:0060070 130 0.106
response to fibroblast growth factor GO:0071774 47 0.106
anion transmembrane transport GO:0098656 71 0.106
central nervous system neuron axonogenesis GO:0021955 28 0.105
Fly
photoreceptor cell fate commitment GO:0046552 2 0.104
cerebellar purkinje cell layer development GO:0021680 26 0.104
locomotory behavior GO:0007626 195 0.103
head morphogenesis GO:0060323 34 0.103
palate development GO:0060021 76 0.103
cardiac muscle tissue morphogenesis GO:0055008 44 0.103
regulation of response to drug GO:2001023 2 0.102
establishment of glial blood brain barrier GO:0060857 2 0.102
regulation of cell cycle GO:0051726 281 0.101
protein secretion GO:0009306 111 0.101
aortic valve morphogenesis GO:0003180 4 0.101
extracellular structure organization GO:0043062 148 0.100
negative regulation of glial cell proliferation GO:0060253 4 0.100
dna metabolic process GO:0006259 303 0.100
mesoderm morphogenesis GO:0048332 64 0.100
muscle tissue development GO:0060537 308 0.098
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.097
maintenance of apical basal cell polarity GO:0035090 3 0.097
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.097
chromatin modification GO:0016568 187 0.097
somatotropin secreting cell differentiation GO:0060126 4 0.096
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.096
metanephros morphogenesis GO:0003338 24 0.094
primary prostatic bud elongation GO:0060516 2 0.094
cardiac cell fate determination GO:0060913 2 0.094
response to histamine GO:0034776 1 0.093
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.093
tube closure GO:0060606 91 0.093
cellular response to ammonium ion GO:0071242 2 0.092
endocrine system development GO:0035270 98 0.092
cerebellum formation GO:0021588 1 0.091
epithelial cell differentiation involved in kidney development GO:0035850 23 0.091
mesodermal cell differentiation GO:0048333 22 0.090
positive regulation of mapk cascade GO:0043410 170 0.090
rhombomere morphogenesis GO:0021593 2 0.090
regulation of neural precursor cell proliferation GO:2000177 70 0.090
renal vesicle development GO:0072087 17 0.090
pigmentation GO:0043473 71 0.090
Mouse
adult behavior GO:0030534 135 0.089
neuromuscular process controlling posture GO:0050884 14 0.088
regulation of cell migration GO:0030334 219 0.088
cardiac right atrium morphogenesis GO:0003213 3 0.088
nuclear division GO:0000280 158 0.088
cell cell junction organization GO:0045216 72 0.087
cardiac cell fate specification GO:0060912 2 0.086
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.086
positive regulation of cell cycle GO:0045787 92 0.086
synaptic transmission glycinergic GO:0060012 2 0.085
positive regulation of cell development GO:0010720 237 0.085
axon cargo transport GO:0008088 33 0.084
organ growth GO:0035265 117 0.084
mesenchymal cell differentiation GO:0048762 107 0.083
rhombomere 2 development GO:0021568 2 0.083
dopaminergic neuron differentiation GO:0071542 14 0.083
negative regulation of cellular amine metabolic process GO:0033239 1 0.083
eye photoreceptor cell fate commitment GO:0042706 2 0.083
negative regulation of gastrulation GO:2000542 3 0.082
regulation of axon extension GO:0030516 43 0.081
embryonic epithelial tube formation GO:0001838 130 0.081
forebrain morphogenesis GO:0048853 17 0.081
skeletal system development GO:0001501 356 0.080
regulation of neurotransmitter levels GO:0001505 87 0.080
stem cell fate specification GO:0048866 3 0.079
medial motor column neuron differentiation GO:0021526 2 0.079
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.079
organonitrogen compound catabolic process GO:1901565 264 0.079
pyramidal neuron migration GO:0021852 1 0.078
cardiac septum development GO:0003279 59 0.078
regulation of ion transmembrane transport GO:0034765 119 0.078
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.078
leukocyte proliferation GO:0070661 172 0.078
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.077
proprioception GO:0019230 4 0.077
cerebellar granule cell differentiation GO:0021707 9 0.077
positive regulation of mitosis GO:0045840 14 0.077
gas homeostasis GO:0033483 3 0.077
meiotic nuclear division GO:0007126 115 0.077
regulation of interleukin 1 alpha production GO:0032650 4 0.077
ectodermal placode formation GO:0060788 16 0.077
regulation of secretion by cell GO:1903530 249 0.076
muscle tissue morphogenesis GO:0060415 53 0.076
tissue homeostasis GO:0001894 115 0.076
regulation of stem cell maintenance GO:2000036 17 0.076
nephric duct elongation GO:0035849 1 0.075
regulation of auditory receptor cell differentiation GO:0045607 4 0.075
morphogenesis of a branching epithelium GO:0061138 193 0.075
primitive streak formation GO:0090009 10 0.075
cellular ketone metabolic process GO:0042180 84 0.074
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.074
lens morphogenesis in camera type eye GO:0002089 24 0.074
mesenchymal cell proliferation GO:0010463 44 0.073
ventral spinal cord interneuron fate commitment GO:0060579 14 0.073
endocardial cushion morphogenesis GO:0003203 18 0.072
regulation of synaptic plasticity GO:0048167 87 0.072
hypothalamus development GO:0021854 16 0.072
organic cyclic compound catabolic process GO:1901361 295 0.072
negative regulation of synapse maturation GO:2000297 2 0.072
regulation of vesicle mediated transport GO:0060627 139 0.071
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.071
cardiac muscle cell myoblast differentiation GO:0060379 8 0.071
pharyngeal system development GO:0060037 17 0.070
endoderm formation GO:0001706 20 0.070
neuromuscular process controlling balance GO:0050885 59 0.070
embryonic placenta development GO:0001892 98 0.070
cation transport GO:0006812 399 0.070
learning GO:0007612 98 0.069
mitral valve development GO:0003174 4 0.069
motor neuron axon guidance GO:0008045 26 0.069
striated muscle tissue development GO:0014706 293 0.069
embryonic camera type eye development GO:0031076 36 0.068
negative regulation of bmp signaling pathway GO:0030514 35 0.068
negative regulation of cellular component organization GO:0051129 194 0.068
mesenchymal to epithelial transition GO:0060231 12 0.068
cell proliferation in external granule layer GO:0021924 10 0.068
multicellular organismal signaling GO:0035637 91 0.067
cell adhesion GO:0007155 329 0.067
negative regulation of osteoblast differentiation GO:0045668 30 0.067
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.066
cell migration involved in gastrulation GO:0042074 13 0.066
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.065
neural precursor cell proliferation GO:0061351 121 0.065
fat cell differentiation GO:0045444 160 0.065
visual perception GO:0007601 52 0.065
regulation of retina development in camera type eye GO:1902866 3 0.065
ensheathment of neurons GO:0007272 76 0.065
intestinal epithelial structure maintenance GO:0060729 4 0.064
forebrain neuron development GO:0021884 30 0.064
metanephric tubule development GO:0072170 18 0.064
sensory system development GO:0048880 3 0.064
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.064
embryonic nail plate morphogenesis GO:0035880 3 0.064
regulation of erk1 and erk2 cascade GO:0070372 71 0.064
forebrain ventricular zone progenitor cell division GO:0021869 6 0.064
negative regulation of neuron apoptotic process GO:0043524 92 0.063
regulation of cerebellar granule cell precursor proliferation GO:0021936 12 0.063
cardiac ventricle development GO:0003231 83 0.063
homeostasis of number of cells GO:0048872 210 0.063
epithalamus development GO:0021538 2 0.063
ras protein signal transduction GO:0007265 77 0.063
regulation of transporter activity GO:0032409 57 0.062
intermediate filament cytoskeleton organization GO:0045104 26 0.062
negative regulation of organelle organization GO:0010639 90 0.062
neural plate morphogenesis GO:0001839 9 0.062
paraxial mesodermal cell differentiation GO:0048342 2 0.062
epithelial tube morphogenesis GO:0060562 303 0.062
columnar cuboidal epithelial cell development GO:0002066 29 0.062
organelle localization GO:0051640 179 0.061
somatotropin secreting cell development GO:0060133 2 0.061
carbon catabolite activation of transcription GO:0045991 4 0.061
macromolecular complex disassembly GO:0032984 43 0.060
central nervous system segmentation GO:0035283 3 0.060
kidney epithelium development GO:0072073 121 0.060
nephric duct formation GO:0072179 4 0.060
olfactory bulb development GO:0021772 30 0.060
regulation of erythrocyte differentiation GO:0045646 23 0.059
cerebral cortex tangential migration GO:0021800 7 0.059
membrane organization GO:0061024 245 0.059
Worm
positive regulation of cell motility GO:2000147 116 0.059
mesonephric duct formation GO:0072181 2 0.058
regulation of binding GO:0051098 111 0.058
myelination GO:0042552 74 0.058
ureteric bud development GO:0001657 94 0.058
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.057
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.057
spinal cord association neuron differentiation GO:0021527 14 0.057
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.057
brain segmentation GO:0035284 3 0.057
oviduct development GO:0060066 3 0.056
cell growth GO:0016049 130 0.056
positive regulation of cell cycle process GO:0090068 61 0.056
metanephric epithelium development GO:0072207 21 0.056
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.055
heart process GO:0003015 94 0.055
dorsal ventral axon guidance GO:0033563 3 0.055
cation transmembrane transport GO:0098655 266 0.055
angiogenesis GO:0001525 201 0.054
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.054
cell differentiation involved in kidney development GO:0061005 33 0.054
cell junction organization GO:0034330 77 0.054
somitogenesis GO:0001756 69 0.054
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.054
lung induction GO:0060492 3 0.054
positive regulation of binding GO:0051099 49 0.054
interneuron migration from the subpallium to the cortex GO:0021830 7 0.054
positive regulation of cell death GO:0010942 224 0.054
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.054
extracellular matrix organization GO:0030198 147 0.053
exocytosis GO:0006887 121 0.053
peripheral nervous system neuron development GO:0048935 9 0.053
establishment of organelle localization GO:0051656 122 0.053
granulocyte colony stimulating factor production GO:0071611 1 0.053
hindlimb morphogenesis GO:0035137 42 0.053
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.053
metanephric nephron tubule formation GO:0072289 4 0.053
regulation of muscle tissue development GO:1901861 97 0.053
positive regulation of glial cell differentiation GO:0045687 21 0.053
regulation of cation channel activity GO:2001257 22 0.053
myeloid cell differentiation GO:0030099 233 0.052
neuromuscular process GO:0050905 99 0.052
tendon formation GO:0035992 4 0.052
blood vessel morphogenesis GO:0048514 285 0.052
renal vesicle induction GO:0072034 3 0.052
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.052
regulation of establishment of protein localization GO:0070201 181 0.052
axon ensheathment GO:0008366 76 0.052
cerebellar granular layer development GO:0021681 13 0.052
myeloid cell homeostasis GO:0002262 114 0.052
renal tubule development GO:0061326 87 0.052
regulation of gastrulation GO:0010470 16 0.051
ventral spinal cord interneuron specification GO:0021521 11 0.051
positive regulation of chondrocyte differentiation GO:0032332 13 0.051
regulation of cytokine production GO:0001817 266 0.051
positive regulation of protein transport GO:0051222 93 0.051
cerebral cortex gabaergic interneuron development GO:0021894 6 0.051
neural crest cell differentiation GO:0014033 54 0.051
nephron epithelium development GO:0072009 92 0.051
actin cytoskeleton organization GO:0030036 220 0.051
associative learning GO:0008306 61 0.050

En2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.172
disease of anatomical entity DOID:7 0 0.172
musculoskeletal system disease DOID:17 0 0.172
connective tissue disease DOID:65 0 0.172