Mus musculus

82 known processes

Isg15

ISG15 ubiquitin-like modifier

(Aliases: MGC103144,G1p2,Irfp,UCRP,IGI15,IP17,MGC18616,MGC130321)

Isg15 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of viral genome replication GO:0045071 10 1.000
Human
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.971
Human
negative regulation of viral process GO:0048525 23 0.962
Human
viral life cycle GO:0019058 36 0.959
Human
isg15 protein conjugation GO:0032020 4 0.951
cellular response to interferon alpha GO:0035457 4 0.930
response to phenylpropanoid GO:0080184 22 0.822
rig i signaling pathway GO:0039529 4 0.709
positive regulation of rig i signaling pathway GO:1900246 1 0.691
response to stilbenoid GO:0035634 22 0.690
cellular response to interferon beta GO:0035458 21 0.688
defense response to other organism GO:0098542 197 0.594
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.592
Human
interspecies interaction between organisms GO:0044419 83 0.581
Human
cellular response to type i interferon GO:0071357 10 0.558
regulation of defense response to virus by host GO:0050691 8 0.554
viral genome replication GO:0019079 17 0.547
Human
negative regulation of defense response to virus by host GO:0050689 1 0.520
production of small rna involved in gene silencing by rna GO:0070918 6 0.510
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.502
negative regulation of cell proliferation GO:0008285 296 0.486
pattern recognition receptor signaling pathway GO:0002221 47 0.486
regulation of response to biotic stimulus GO:0002831 38 0.477
t helper 2 cell cytokine production GO:0035745 4 0.467
negative regulation of interferon beta biosynthetic process GO:0045358 1 0.455
t helper 17 cell lineage commitment GO:0072540 4 0.453
regulation of viral genome replication GO:0045069 13 0.452
Human
viral process GO:0016032 41 0.426
Human
cellular nitrogen compound catabolic process GO:0044270 280 0.403
positive regulation of interferon alpha production GO:0032727 4 0.365
positive regulation of viral genome replication GO:0045070 2 0.348
response to type i interferon GO:0034340 12 0.345
Human
regulation of multi organism process GO:0043900 111 0.342
Human
response to organic cyclic compound GO:0014070 198 0.336
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.335
response to interferon alpha GO:0035455 7 0.322
purine ribonucleotide catabolic process GO:0009154 208 0.319
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.318
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.306
defense response to bacterium GO:0042742 119 0.304
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.294
nucleoside triphosphate catabolic process GO:0009143 205 0.294
regulation of rig i signaling pathway GO:0039535 2 0.292
activation of innate immune response GO:0002218 56 0.290
negative regulation of multi organism process GO:0043901 68 0.278
Human
immune effector process GO:0002252 321 0.267
histone h4 acetylation GO:0043967 10 0.264
positive regulation of response to cytokine stimulus GO:0060760 11 0.256
response to interferon beta GO:0035456 22 0.242
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.239
response to dsrna GO:0043331 30 0.213
organic cyclic compound catabolic process GO:1901361 295 0.208
defense response to virus GO:0051607 68 0.203
negative regulation of interferon beta production GO:0032688 3 0.200
purine nucleotide metabolic process GO:0006163 302 0.199
intracellular transport of virus GO:0075733 1 0.192
nucleotide metabolic process GO:0009117 332 0.188
innate immune response activating signal transduction GO:0002758 50 0.171
protein methylation GO:0006479 81 0.166
purine ribonucleoside metabolic process GO:0046128 241 0.165
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.165
protein alkylation GO:0008213 81 0.163
response to protozoan GO:0001562 28 0.162
cellular macromolecule catabolic process GO:0044265 206 0.161
purine ribonucleoside catabolic process GO:0046130 205 0.161
positive t cell selection GO:0043368 23 0.160
macromolecule catabolic process GO:0009057 281 0.160
cell fate commitment GO:0045165 210 0.155
defense response to protozoan GO:0042832 25 0.155
purine containing compound catabolic process GO:0072523 213 0.147
immune response regulating signaling pathway GO:0002764 125 0.140
viral gene expression GO:0019080 3 0.138
nucleobase containing small molecule metabolic process GO:0055086 352 0.133
protein modification by small protein conjugation GO:0032446 187 0.131
Human
myeloid leukocyte differentiation GO:0002573 119 0.123
purine nucleoside metabolic process GO:0042278 241 0.122
ribonucleoside triphosphate metabolic process GO:0009199 220 0.122
purine ribonucleotide metabolic process GO:0009150 290 0.121
pre mirna processing GO:0031054 3 0.120
regulation of defense response GO:0031347 233 0.116
skin development GO:0043588 220 0.116
positive regulation of protein complex assembly GO:0031334 45 0.111
type i interferon production GO:0032606 29 0.111
regulation of t helper 2 cell cytokine production GO:2000551 3 0.109
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.107
histone acetylation GO:0016573 41 0.106
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.105
negative regulation of immune effector process GO:0002698 55 0.104
mda 5 signaling pathway GO:0039530 1 0.104
stem cell differentiation GO:0048863 268 0.103
ribonucleoside catabolic process GO:0042454 206 0.100
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.099
organophosphate catabolic process GO:0046434 232 0.096
intracellular protein transport GO:0006886 204 0.096
regulation of binding GO:0051098 111 0.095
leukocyte mediated immunity GO:0002443 174 0.095
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.092
chromatin organization GO:0006325 206 0.090
regulation of cytokine biosynthetic process GO:0042035 59 0.089
purine containing compound metabolic process GO:0072521 311 0.088
heterocycle catabolic process GO:0046700 280 0.088
nucleoside catabolic process GO:0009164 206 0.087
toll like receptor 7 signaling pathway GO:0034154 4 0.086
myeloid cell differentiation GO:0030099 233 0.086
protein acylation GO:0043543 64 0.085
cytokine mediated signaling pathway GO:0019221 115 0.083
ribose phosphate metabolic process GO:0019693 291 0.083
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 2 0.083
cellular response to interferon gamma GO:0071346 25 0.080
immune response activating signal transduction GO:0002757 116 0.077
regulation of protein transport GO:0051223 163 0.076
hair follicle cell proliferation GO:0071335 3 0.074
t cell activation GO:0042110 289 0.070
immunoglobulin mediated immune response GO:0016064 69 0.069
regulation of defense response to bacterium GO:1900424 3 0.069
protein modification by small protein conjugation or removal GO:0070647 207 0.067
Human
endocytosis GO:0006897 168 0.066
positive regulation of defense response GO:0031349 124 0.066
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.066
positive regulation of immune effector process GO:0002699 107 0.064
positive regulation of mirna metabolic process GO:2000630 1 0.063
response to interferon gamma GO:0034341 34 0.061
organophosphate biosynthetic process GO:0090407 122 0.061
regulation of cellular component biogenesis GO:0044087 181 0.061
regulation of lymphocyte activation GO:0051249 240 0.060
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.060
negative regulation of cytokine production GO:0001818 84 0.059
muscle cell development GO:0055001 133 0.058
schwann cell proliferation GO:0014010 2 0.058
ribonucleotide metabolic process GO:0009259 291 0.058
regulation of growth of symbiont in host GO:0044126 19 0.057
adaptive immune response GO:0002250 155 0.057
transport of virus GO:0046794 1 0.057
cellular response to lipid GO:0071396 145 0.055
transcription initiation from rna polymerase ii promoter GO:0006367 8 0.054
rna catabolic process GO:0006401 29 0.054
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.053
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.052
cellular metal ion homeostasis GO:0006875 151 0.052
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.052
regulation of schwann cell proliferation GO:0010624 2 0.051
positive regulation of cellular component biogenesis GO:0044089 94 0.051
interferon beta production GO:0032608 16 0.051
interaction with host GO:0051701 22 0.051
regulation of leukocyte mediated immunity GO:0002703 104 0.051
aromatic compound catabolic process GO:0019439 286 0.050
cellular homeostasis GO:0019725 240 0.048
muscle tissue development GO:0060537 308 0.048
alpha beta t cell differentiation GO:0046632 69 0.046
gland development GO:0048732 330 0.045
leukocyte proliferation GO:0070661 172 0.044
positive regulation of binding GO:0051099 49 0.044
cytokine metabolic process GO:0042107 71 0.044
leukocyte differentiation GO:0002521 342 0.043
regulation of protein complex assembly GO:0043254 83 0.043
macromolecule methylation GO:0043414 120 0.042
spleen development GO:0048536 39 0.042
negative regulation of t cell differentiation GO:0045581 23 0.042
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.041
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.040
regulation of cell activation GO:0050865 289 0.040
leukocyte activation involved in immune response GO:0002366 126 0.040
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.038
divalent metal ion transport GO:0070838 172 0.038
internal peptidyl lysine acetylation GO:0018393 42 0.038
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 2 0.038
protein oligomerization GO:0051259 67 0.038
cation transport GO:0006812 399 0.038
epidermis development GO:0008544 187 0.037
homeostasis of number of cells GO:0048872 210 0.037
divalent inorganic cation homeostasis GO:0072507 138 0.037
limb development GO:0060173 166 0.036
regulation of hematopoietic stem cell proliferation GO:1902033 3 0.036
skeletal system development GO:0001501 356 0.036
cell activation involved in immune response GO:0002263 126 0.036
covalent chromatin modification GO:0016569 163 0.036
regulation of cytokine production GO:0001817 266 0.035
Human
regulation of cell motility GO:2000145 236 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
epithelial tube morphogenesis GO:0060562 303 0.035
transmission of nerve impulse GO:0019226 76 0.035
t helper 17 cell differentiation GO:0072539 7 0.035
neutrophil migration GO:1990266 37 0.035
innate immune response GO:0045087 157 0.034
Human
pallium development GO:0021543 120 0.034
negative regulation of cellular component organization GO:0051129 194 0.034
positive regulation of cytokine biosynthetic process GO:0042108 40 0.034
organonitrogen compound biosynthetic process GO:1901566 192 0.034
alpha beta t cell activation GO:0046631 91 0.033
regulation of dna templated transcription initiation GO:2000142 7 0.033
alpha beta t cell activation involved in immune response GO:0002287 31 0.033
negative regulation of regulatory t cell differentiation GO:0045590 2 0.033
regulation of t cell activation GO:0050863 170 0.033
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.032
glycosyl compound metabolic process GO:1901657 246 0.032
metal ion homeostasis GO:0055065 189 0.032
protein import GO:0017038 101 0.032
histone modification GO:0016570 159 0.032
cd8 positive alpha beta t cell differentiation GO:0043374 9 0.032
positive regulation of type i interferon production GO:0032481 14 0.032
negative regulation of rig i signaling pathway GO:0039536 2 0.031
nucleoside metabolic process GO:0009116 246 0.031
myeloid dendritic cell activation GO:0001773 25 0.031
myeloid cell homeostasis GO:0002262 114 0.031
cytoplasmic transport GO:0016482 234 0.031
cellular amino acid metabolic process GO:0006520 103 0.030
alpha beta t cell proliferation GO:0046633 21 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
Human
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.030
negative regulation of growth GO:0045926 99 0.030
multicellular organism growth GO:0035264 161 0.029
cd4 positive alpha beta t cell lineage commitment GO:0043373 6 0.029
anion transport GO:0006820 177 0.029
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.029
glycosyl compound catabolic process GO:1901658 206 0.029
limb morphogenesis GO:0035108 149 0.028
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.028
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.028
forebrain development GO:0030900 302 0.028
ossification GO:0001503 216 0.028
peptidyl lysine methylation GO:0018022 29 0.028
cellular response to cytokine stimulus GO:0071345 189 0.028
regulation of neutrophil mediated killing of fungus GO:0070953 1 0.027
regulation of dna binding GO:0051101 39 0.027
nucleotide biosynthetic process GO:0009165 78 0.027
regulation of interleukin 12 production GO:0032655 30 0.027
cellular ion homeostasis GO:0006873 165 0.026
organelle assembly GO:0070925 177 0.026
calcium ion transport GO:0006816 159 0.026
guanosine containing compound metabolic process GO:1901068 144 0.026
mammary gland epithelium development GO:0061180 65 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
neuronal action potential GO:0019228 54 0.026
positive regulation of cell development GO:0010720 237 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
protein secretion GO:0009306 111 0.025
lymphocyte differentiation GO:0030098 242 0.025
positive regulation of mast cell differentiation GO:0060376 1 0.024
interleukin 12 biosynthetic process GO:0042090 8 0.024
negative regulation of viral release from host cell GO:1902187 6 0.024
lymphocyte activation involved in immune response GO:0002285 93 0.024
regulation of toll like receptor signaling pathway GO:0034121 20 0.024
movement in host environment GO:0052126 15 0.024
regulation of mapk cascade GO:0043408 248 0.024
regulation of innate immune response GO:0045088 91 0.024
connective tissue development GO:0061448 179 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
regulation of adaptive immune response GO:0002819 90 0.023
regulation of membrane potential GO:0042391 192 0.023
lymphocyte mediated immunity GO:0002449 139 0.023
modification of morphology or physiology of other organism GO:0035821 18 0.023
histone h3 acetylation GO:0043966 14 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
killing by host of symbiont cells GO:0051873 11 0.023
maintenance of location GO:0051235 89 0.023
autophagy GO:0006914 45 0.023
regulation of homeostatic process GO:0032844 182 0.023
myelination in peripheral nervous system GO:0022011 19 0.023
dendritic cell differentiation GO:0097028 26 0.023
regulation of leukocyte proliferation GO:0070663 121 0.023
stem cell development GO:0048864 219 0.022
nucleoside phosphate biosynthetic process GO:1901293 79 0.022
atp metabolic process GO:0046034 75 0.022
hair follicle morphogenesis GO:0031069 29 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
Human
hair follicle development GO:0001942 85 0.022
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.022
purine nucleotide biosynthetic process GO:0006164 65 0.022
citrate metabolic process GO:0006101 3 0.022
positive regulation of ion transport GO:0043270 65 0.022
negative regulation of syncytium formation by plasma membrane fusion GO:0034242 5 0.022
regulation of cell migration GO:0030334 219 0.022
dna metabolic process GO:0006259 303 0.021
regulation of neuron differentiation GO:0045664 281 0.021
modification dependent macromolecule catabolic process GO:0043632 133 0.021
cellular chemical homeostasis GO:0055082 215 0.021
regulation of alpha beta t cell proliferation GO:0046640 18 0.021
negative regulation of myoblast differentiation GO:0045662 18 0.021
cellular ketone metabolic process GO:0042180 84 0.021
keratinocyte proliferation GO:0043616 21 0.021
regulation of viral transcription GO:0046782 3 0.021
negative regulation of growth of symbiont in host GO:0044130 19 0.021
morphogenesis of a branching structure GO:0001763 203 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
negative regulation of molecular function GO:0044092 258 0.021
purine nucleoside monophosphate metabolic process GO:0009126 81 0.021
t cell differentiation GO:0030217 174 0.021
positive regulation of neutrophil mediated killing of fungus GO:0070965 1 0.021
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.021
posttranscriptional gene silencing GO:0016441 10 0.021
positive regulation of cytokine production GO:0001819 174 0.020
striated muscle cell development GO:0055002 125 0.020
sequestering of metal ion GO:0051238 19 0.020
meiotic cell cycle process GO:1903046 77 0.020
t cell proliferation GO:0042098 120 0.020
negative regulation of binding GO:0051100 39 0.020
regulation of ion transport GO:0043269 215 0.020
cation homeostasis GO:0055080 212 0.020
regulation of cell cycle GO:0051726 281 0.020
peptidyl amino acid modification GO:0018193 336 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
nucleotide catabolic process GO:0009166 217 0.020
response to lipopolysaccharide GO:0032496 128 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
transmembrane transport GO:0055085 412 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
carbohydrate metabolic process GO:0005975 230 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
regulation of organelle organization GO:0033043 289 0.019
phagocytosis GO:0006909 66 0.019
cellular response to molecule of bacterial origin GO:0071219 83 0.019
keratinocyte differentiation GO:0030216 48 0.019
striated muscle tissue development GO:0014706 293 0.019
negative regulation of immune system process GO:0002683 209 0.018
action potential GO:0001508 78 0.018
regulation of intracellular transport GO:0032386 159 0.018
positive regulation of organelle organization GO:0010638 128 0.018
regulation of protein binding GO:0043393 60 0.018
modification dependent protein catabolic process GO:0019941 133 0.018
syncytium formation by plasma membrane fusion GO:0000768 42 0.018
sequestering of calcium ion GO:0051208 18 0.018
neutrophil mediated killing of fungus GO:0070947 3 0.018
myeloid dendritic cell differentiation GO:0043011 16 0.018
regulation of proteolysis GO:0030162 164 0.018
ion transmembrane transport GO:0034220 361 0.018
internal protein amino acid acetylation GO:0006475 42 0.018
positive regulation of lymphocyte activation GO:0051251 140 0.018
negative regulation of defense response to virus GO:0050687 6 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
type i interferon biosynthetic process GO:0045351 9 0.018
regulation of skeletal muscle fiber development GO:0048742 36 0.018
negative regulation of lymphocyte activation GO:0051250 91 0.017
response to radiation GO:0009314 165 0.017
glucose metabolic process GO:0006006 92 0.017
negative regulation of response to biotic stimulus GO:0002832 10 0.017
male gamete generation GO:0048232 285 0.017
positive regulation of interferon beta production GO:0032728 8 0.017
leukocyte mediated cytotoxicity GO:0001909 62 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
heart morphogenesis GO:0003007 178 0.017
t helper cell lineage commitment GO:0002295 6 0.017
respiratory system development GO:0060541 190 0.017
response to organonitrogen compound GO:0010243 246 0.017
disruption by host of symbiont cells GO:0051852 11 0.017
regulation of hydrolase activity GO:0051336 246 0.017
interferon alpha production GO:0032607 7 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
disruption of cells of other organism GO:0044364 13 0.016
angiogenesis GO:0001525 201 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
toll like receptor signaling pathway GO:0002224 38 0.016
hair cycle GO:0042633 90 0.016
protein catabolic process GO:0030163 221 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
response to exogenous dsrna GO:0043330 22 0.016
regulation of secretion GO:0051046 274 0.016
regulation of protein localization GO:0032880 231 0.016
glucose homeostasis GO:0042593 128 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
regulation of t cell proliferation GO:0042129 92 0.016
gtp metabolic process GO:0046039 144 0.016
microtubule based process GO:0007017 236 0.016
cardiocyte differentiation GO:0035051 87 0.016
developmental maturation GO:0021700 193 0.016
multicellular organismal signaling GO:0035637 91 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
regulation of cellular amino acid metabolic process GO:0006521 5 0.015
sensory perception GO:0007600 245 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
germ cell development GO:0007281 185 0.015
regulation of type i interferon production GO:0032479 22 0.015
mitotic cell cycle GO:0000278 195 0.015
muscle cell differentiation GO:0042692 261 0.015
negative regulation of homeostatic process GO:0032845 71 0.015
myeloid leukocyte activation GO:0002274 83 0.015
regulation of killing of cells of other organism GO:0051709 4 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.015
divalent inorganic cation transport GO:0072511 178 0.015
cd4 positive alpha beta t cell activation GO:0035710 45 0.015
response to extracellular stimulus GO:0009991 127 0.015
positive regulation of viral process GO:0048524 5 0.015
multi multicellular organism process GO:0044706 109 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
extracellular matrix organization GO:0030198 147 0.014
positive regulation of kinase activity GO:0033674 155 0.014
oligodendrocyte differentiation GO:0048709 53 0.014
schwann cell differentiation GO:0014037 26 0.014
positive regulation of leukocyte differentiation GO:1902107 86 0.014
lung development GO:0030324 164 0.014
regulation of system process GO:0044057 200 0.014
i kappab kinase nf kappab signaling GO:0007249 85 0.014
regulation of defense response to fungus GO:1900150 1 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
regulation of neutrophil mediated cytotoxicity GO:0070948 2 0.014
appendage morphogenesis GO:0035107 149 0.013
positive regulation of dna binding GO:0043388 14 0.013
positive regulation of killing of cells of other organism GO:0051712 3 0.013
cell type specific apoptotic process GO:0097285 268 0.013
positive regulation of hematopoietic stem cell proliferation GO:1902035 2 0.013
negative regulation of nervous system development GO:0051961 156 0.013
b cell mediated immunity GO:0019724 71 0.013
carboxylic acid transport GO:0046942 100 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
regulation of metal ion transport GO:0010959 106 0.013
hexose metabolic process GO:0019318 98 0.013
positive regulation of striated muscle cell differentiation GO:0051155 35 0.013
growth of symbiont involved in interaction with host GO:0044116 23 0.013
positive regulation of t cell differentiation GO:0045582 52 0.013
blood vessel morphogenesis GO:0048514 285 0.013
gene silencing by mirna GO:0035195 10 0.013
telencephalon development GO:0021537 186 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
viral transcription GO:0019083 3 0.013
skeletal muscle organ development GO:0060538 163 0.013
response to growth factor GO:0070848 198 0.013
rna interference GO:0016246 2 0.013
appendage development GO:0048736 166 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
translation GO:0006412 93 0.013
negative regulation of intracellular protein transport GO:0090317 27 0.013
nerve development GO:0021675 67 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
negative regulation of leukocyte differentiation GO:1902106 51 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
t helper cell differentiation GO:0042093 28 0.013
mechanoreceptor differentiation GO:0042490 67 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
regulation of alpha beta t cell activation GO:0046634 53 0.013
positive regulation of adaptive immune response GO:0002821 61 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
axon ensheathment GO:0008366 76 0.012
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 10 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
regulation of muscle tissue development GO:1901861 97 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
cellular protein complex assembly GO:0043623 116 0.012
pyrimidine containing compound catabolic process GO:0072529 3 0.012
interferon beta biosynthetic process GO:0045350 4 0.012
regulation of myoblast differentiation GO:0045661 29 0.012
spermatid differentiation GO:0048515 115 0.012
olfactory bulb interneuron differentiation GO:0021889 12 0.012
stem cell proliferation GO:0072089 117 0.012
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
organism emergence from protective structure GO:0071684 4 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
regulation of cytokine production involved in immune response GO:0002718 26 0.012
regulation of interferon gamma production GO:0032649 57 0.012
Human
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
regulation of interferon alpha production GO:0032647 5 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
cellular protein catabolic process GO:0044257 155 0.011
mapk cascade GO:0000165 281 0.011
carbohydrate homeostasis GO:0033500 128 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
regulation of neutrophil mediated killing of bacterium GO:0070950 1 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
b cell differentiation GO:0030183 78 0.011
response to nutrient levels GO:0031667 109 0.011
positive regulation of nervous system development GO:0051962 221 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
generation of precursor metabolites and energy GO:0006091 103 0.011
myotube cell development GO:0014904 60 0.011
sensory organ morphogenesis GO:0090596 242 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
rna processing GO:0006396 105 0.011
cell adhesion GO:0007155 329 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
cellular amine metabolic process GO:0044106 44 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
Human
positive regulation of ossification GO:0045778 47 0.011
fat cell differentiation GO:0045444 160 0.011
calcium ion homeostasis GO:0055074 127 0.011
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.011
positive regulation of cell migration GO:0030335 109 0.011
ras protein signal transduction GO:0007265 77 0.011
leukocyte migration GO:0050900 124 0.011
regulation of ossification GO:0030278 112 0.011
regulation of actin filament length GO:0030832 45 0.011
cytokine biosynthetic process GO:0042089 68 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
negative regulation of protein binding GO:0032091 17 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010

Isg15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
carbohydrate metabolism disease DOID:0050013 0 0.012
glucose metabolism disease DOID:4194 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
disease of metabolism DOID:0014667 0 0.012