Mus musculus

224 known processes

Nedd4

neural precursor cell expressed, developmentally down-regulated 4

(Aliases: AL023035,mKIAA0093,Nedd4-1,AU019897,AA959633,Nedd4a,E430025J12Rik)

Nedd4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.959
modification dependent protein catabolic process GO:0019941 133 0.949
cellular macromolecule catabolic process GO:0044265 206 0.901
cellular protein catabolic process GO:0044257 155 0.822
pole plasm assembly GO:0007315 2 0.668
modification dependent macromolecule catabolic process GO:0043632 133 0.666
ubiquitin dependent protein catabolic process GO:0006511 129 0.645
protein ubiquitination GO:0016567 171 0.528
negative regulation of phosphorus metabolic process GO:0010563 184 0.508
Mouse
macromolecule catabolic process GO:0009057 281 0.465
mitotic cell cycle GO:0000278 195 0.462
protein modification by small protein conjugation or removal GO:0070647 207 0.449
cellular response to dna damage stimulus GO:0006974 207 0.442
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.434
Human Yeast Mouse
cell adhesion GO:0007155 329 0.424
regulation of mitotic cell cycle GO:0007346 126 0.422
stress activated protein kinase signaling cascade GO:0031098 81 0.367
Mouse
multicellular organism growth GO:0035264 161 0.351
regulation of protein localization GO:0032880 231 0.328
Yeast
transmembrane transport GO:0055085 412 0.326
dna metabolic process GO:0006259 303 0.316
negative regulation of intracellular signal transduction GO:1902532 167 0.292
Mouse
regulation of membrane potential GO:0042391 192 0.288
Human
nucleocytoplasmic transport GO:0006913 139 0.267
Human Yeast
ion transmembrane transport GO:0034220 361 0.260
oxidation reduction process GO:0055114 342 0.237
regulation of cell cycle GO:0051726 281 0.235
cell division GO:0051301 120 0.234
negative regulation of glycogen biosynthetic process GO:0045719 1 0.233
cellular amino acid metabolic process GO:0006520 103 0.232
cellular amine metabolic process GO:0044106 44 0.227
oocyte axis specification GO:0007309 2 0.217
regulation of cellular component biogenesis GO:0044087 181 0.215
Yeast Mouse
regulation of ion transport GO:0043269 215 0.209
cellular response to lipid GO:0071396 145 0.203
response to peptide hormone GO:0043434 127 0.202
oocyte anterior posterior axis specification GO:0007314 2 0.190
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.184
maintenance of location GO:0051235 89 0.180
regulation of defense response GO:0031347 233 0.171
Mouse
cation homeostasis GO:0055080 212 0.168
protein catabolic process GO:0030163 221 0.165
regulation of transmembrane transport GO:0034762 128 0.161
Human Mouse
cellular homeostasis GO:0019725 240 0.159
cellular response to growth factor stimulus GO:0071363 197 0.157
heart contraction GO:0060047 93 0.153
negative regulation of cellular protein metabolic process GO:0032269 247 0.152
peptidyl tyrosine phosphorylation GO:0018108 143 0.152
mitotic cell cycle process GO:1903047 159 0.152
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.149
positive regulation of cell adhesion GO:0045785 80 0.149
response to transforming growth factor beta GO:0071559 88 0.147
inorganic ion transmembrane transport GO:0098660 234 0.146
negative regulation of molecular function GO:0044092 258 0.146
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.144
Mouse
negative regulation of phosphorylation GO:0042326 166 0.144
Mouse
regulation of cell activation GO:0050865 289 0.143
Mouse
immune effector process GO:0002252 321 0.142
Mouse
microtubule cytoskeleton organization GO:0000226 157 0.141
protein localization to nucleus GO:0034504 121 0.139
proteasomal protein catabolic process GO:0010498 98 0.138
Yeast Mouse
polysaccharide metabolic process GO:0005976 39 0.137
negative regulation of protein metabolic process GO:0051248 282 0.134
posttranscriptional regulation of gene expression GO:0010608 155 0.134
regulation of neuron differentiation GO:0045664 281 0.134
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.132
Yeast Mouse
cellular response to hormone stimulus GO:0032870 150 0.131
regulation of intracellular transport GO:0032386 159 0.130
Human Yeast
oocyte construction GO:0007308 2 0.130
cell growth GO:0016049 130 0.130
rhythmic process GO:0048511 174 0.129
energy reserve metabolic process GO:0006112 39 0.129
lipid storage GO:0019915 36 0.128
gonad development GO:0008406 141 0.128
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.127
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.126
transmission of nerve impulse GO:0019226 76 0.126
translation GO:0006412 93 0.126
regulation of insulin receptor signaling pathway GO:0046626 21 0.124
glucose transport GO:0015758 56 0.124
single organism cell adhesion GO:0098602 156 0.121
peptidyl amino acid modification GO:0018193 336 0.118
spermatogenesis GO:0007283 284 0.117
axon regeneration GO:0031103 12 0.116
negative regulation of protein modification process GO:0031400 163 0.114
negative regulation of cell activation GO:0050866 111 0.113
Mouse
nitrogen compound transport GO:0071705 271 0.113
Yeast
nuclear transport GO:0051169 139 0.112
Human Yeast
leukocyte differentiation GO:0002521 342 0.111
germ line stem cell division GO:0042078 2 0.109
axonogenesis GO:0007409 274 0.109
anion transport GO:0006820 177 0.108
action potential GO:0001508 78 0.107
mitotic nuclear division GO:0007067 48 0.107
endocytosis GO:0006897 168 0.106
Human Yeast
regulation of protein serine threonine kinase activity GO:0071900 157 0.106
regulation of protein kinase activity GO:0045859 232 0.106
muscle system process GO:0003012 141 0.105
energy derivation by oxidation of organic compounds GO:0015980 77 0.105
negative regulation of defense response GO:0031348 77 0.105
Mouse
neuron migration GO:0001764 122 0.104
negative regulation of immune system process GO:0002683 209 0.103
Mouse
cell maturation GO:0048469 127 0.103
organelle fission GO:0048285 170 0.102
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.102
glucan metabolic process GO:0044042 32 0.102
t cell activation GO:0042110 289 0.099
mapk cascade GO:0000165 281 0.098
Mouse
apoptotic signaling pathway GO:0097190 306 0.098
telencephalon development GO:0021537 186 0.097
cellular response to insulin stimulus GO:0032869 78 0.097
regulation of protein transport GO:0051223 163 0.096
metal ion homeostasis GO:0055065 189 0.096
insulin receptor signaling pathway GO:0008286 49 0.096
negative regulation of protein transport GO:0051224 46 0.096
schwann cell proliferation GO:0014010 2 0.096
negative regulation of protein phosphorylation GO:0001933 126 0.095
regulation of cell cycle process GO:0010564 160 0.095
response to organic cyclic compound GO:0014070 198 0.095
regulation of glucan biosynthetic process GO:0010962 7 0.094
generation of precursor metabolites and energy GO:0006091 103 0.093
regulation of myeloid cell differentiation GO:0045637 96 0.093
muscle contraction GO:0006936 101 0.088
intracellular protein transport GO:0006886 204 0.088
Human
single organism nuclear import GO:1902593 95 0.087
cellular response to molecule of bacterial origin GO:0071219 83 0.087
response to molecule of bacterial origin GO:0002237 143 0.087
wnt signaling pathway GO:0016055 188 0.086
protein import into nucleus GO:0006606 95 0.085
regulation of cell cycle phase transition GO:1901987 77 0.085
neuron projection guidance GO:0097485 141 0.085
insulin like growth factor receptor signaling pathway GO:0048009 21 0.085
cellular glucan metabolic process GO:0006073 32 0.085
negative regulation of intracellular transport GO:0032387 38 0.084
cellular polysaccharide metabolic process GO:0044264 38 0.083
negative regulation of phosphate metabolic process GO:0045936 184 0.083
Mouse
male germ line stem cell asymmetric division GO:0048133 2 0.083
regulation of cell adhesion GO:0030155 154 0.083
regulation of ion transmembrane transport GO:0034765 119 0.082
Human Mouse
negative regulation of mitotic cell cycle GO:0045930 58 0.081
cellular ion homeostasis GO:0006873 165 0.081
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.080
photoreceptor cell development GO:0042461 40 0.080
organelle assembly GO:0070925 177 0.079
single organismal cell cell adhesion GO:0016337 131 0.079
cellular chemical homeostasis GO:0055082 215 0.078
fat cell differentiation GO:0045444 160 0.078
establishment or maintenance of cell polarity GO:0007163 86 0.078
protein kinase b signaling GO:0043491 74 0.077
protein modification by small protein conjugation GO:0032446 187 0.077
regulation of jnk cascade GO:0046328 62 0.076
Mouse
response to organonitrogen compound GO:0010243 246 0.076
regulation of cellular component size GO:0032535 121 0.076
Yeast
negative regulation of leukocyte proliferation GO:0070664 46 0.076
Mouse
regulation of anatomical structure size GO:0090066 178 0.075
Yeast
chemotaxis GO:0006935 247 0.075
regulation of intracellular protein transport GO:0033157 82 0.073
regulation of nucleocytoplasmic transport GO:0046822 73 0.072
Human Yeast
regulation of circadian sleep wake cycle GO:0042749 3 0.072
amine metabolic process GO:0009308 45 0.072
lipid localization GO:0010876 126 0.071
carbohydrate metabolic process GO:0005975 230 0.071
regulation of binding GO:0051098 111 0.071
cellular response to organonitrogen compound GO:0071417 145 0.071
positive regulation of protein phosphorylation GO:0001934 242 0.071
response to lipopolysaccharide GO:0032496 128 0.070
establishment of organelle localization GO:0051656 122 0.070
Yeast
regeneration GO:0031099 38 0.069
neuron maturation GO:0042551 29 0.069
cell junction assembly GO:0034329 52 0.069
Mouse
regulation of translation GO:0006417 71 0.069
cardiac muscle contraction GO:0060048 32 0.068
connective tissue development GO:0061448 179 0.068
sodium ion transport GO:0006814 73 0.068
regulation of cellular ketone metabolic process GO:0010565 66 0.068
Yeast
regulation of protein kinase b signaling GO:0051896 56 0.067
mrna metabolic process GO:0016071 84 0.066
response to ph GO:0009268 14 0.066
germ cell development GO:0007281 185 0.066
circadian rhythm GO:0007623 114 0.065
regulation of engulfment of apoptotic cell GO:1901074 2 0.065
intracellular mrna localization GO:0008298 4 0.065
negative regulation of epithelial cell proliferation GO:0050680 64 0.065
neuronal action potential GO:0019228 54 0.065
sensory perception of mechanical stimulus GO:0050954 107 0.064
lymphocyte differentiation GO:0030098 242 0.064
regulation of establishment of protein localization GO:0070201 181 0.062
protein targeting GO:0006605 143 0.062
Human
dna recombination GO:0006310 92 0.062
developmental maturation GO:0021700 193 0.061
cellular response to lipopolysaccharide GO:0071222 77 0.061
regulation of transporter activity GO:0032409 57 0.061
Human Mouse
developmental cell growth GO:0048588 84 0.060
leukocyte activation involved in immune response GO:0002366 126 0.060
nucleoside phosphate metabolic process GO:0006753 338 0.060
cell type specific apoptotic process GO:0097285 268 0.060
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.060
regulation of protein targeting GO:1903533 61 0.060
locomotory behavior GO:0007626 195 0.059
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.058
multicellular organismal signaling GO:0035637 91 0.058
carbohydrate derivative biosynthetic process GO:1901137 183 0.058
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.058
positive regulation of protein kinase activity GO:0045860 144 0.058
cell substrate adhesion GO:0031589 130 0.058
myeloid leukocyte differentiation GO:0002573 119 0.058
adaptive immune response GO:0002250 155 0.058
peptidyl tyrosine modification GO:0018212 145 0.057
negative regulation of glycogen metabolic process GO:0070874 2 0.057
inorganic cation transmembrane transport GO:0098662 207 0.057
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.056
Mouse
axon guidance GO:0007411 141 0.056
actin polymerization or depolymerization GO:0008154 54 0.056
urogenital system development GO:0001655 261 0.055
positive regulation of mapk cascade GO:0043410 170 0.055
negative regulation of t cell activation GO:0050868 65 0.055
Mouse
response to peptide GO:1901652 136 0.055
stress activated mapk cascade GO:0051403 80 0.055
Mouse
positive regulation of programmed cell death GO:0043068 218 0.055
neural precursor cell proliferation GO:0061351 121 0.054
i kappab kinase nf kappab signaling GO:0007249 85 0.054
epidermis development GO:0008544 187 0.053
myelination GO:0042552 74 0.053
retina development in camera type eye GO:0060041 119 0.053
chromatin modification GO:0016568 187 0.053
nuclear import GO:0051170 95 0.052
response to uv GO:0009411 44 0.052
Human Yeast
negative regulation of transporter activity GO:0032410 7 0.051
purine containing compound metabolic process GO:0072521 311 0.051
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 2 0.050
cation transport GO:0006812 399 0.050
regulation of protein catabolic process GO:0042176 108 0.050
glycogen metabolic process GO:0005977 32 0.050
response to oxidative stress GO:0006979 123 0.050
regulation of cellular response to growth factor stimulus GO:0090287 82 0.050
striated muscle tissue development GO:0014706 293 0.050
protein import GO:0017038 101 0.049
defense response to other organism GO:0098542 197 0.049
Mouse
forebrain development GO:0030900 302 0.049
hexose transport GO:0008645 56 0.049
lateral inhibition GO:0046331 1 0.049
positive regulation of neuron projection development GO:0010976 79 0.049
negative regulation of cellular component organization GO:0051129 194 0.048
regulation of protein import into nucleus GO:0042306 52 0.048
cellular nitrogen compound catabolic process GO:0044270 280 0.048
regulation of cellular response to insulin stimulus GO:1900076 30 0.047
cellular response to peptide hormone stimulus GO:0071375 92 0.047
actin cytoskeleton organization GO:0030036 220 0.047
Yeast
regulation of heart contraction GO:0008016 77 0.047
cellular ketone metabolic process GO:0042180 84 0.047
Yeast
regulation of system process GO:0044057 200 0.047
Rat
muscle cell differentiation GO:0042692 261 0.046
myeloid cell differentiation GO:0030099 233 0.046
lamellipodium organization GO:0097581 29 0.046
regulation of myeloid leukocyte differentiation GO:0002761 58 0.046
purine nucleoside triphosphate catabolic process GO:0009146 203 0.046
cell activation involved in immune response GO:0002263 126 0.045
reactive oxygen species biosynthetic process GO:1903409 8 0.045
sodium ion transmembrane transport GO:0035725 49 0.045
t cell proliferation GO:0042098 120 0.045
Mouse
axon ensheathment GO:0008366 76 0.045
response to insulin GO:0032868 100 0.045
regulation of dna replication GO:0006275 17 0.044
myeloid cell homeostasis GO:0002262 114 0.043
keratinocyte differentiation GO:0030216 48 0.043
regulation of lymphocyte differentiation GO:0045619 107 0.043
protein localization to organelle GO:0033365 185 0.043
Human
regulation of vacuole organization GO:0044088 4 0.043
multi multicellular organism process GO:0044706 109 0.043
cellular metal ion homeostasis GO:0006875 151 0.043
regulation of mitotic cell cycle phase transition GO:1901990 73 0.042
monosaccharide transport GO:0015749 58 0.042
actin filament based movement GO:0030048 23 0.042
phagocytosis GO:0006909 66 0.042
somatic diversification of immune receptors GO:0002200 53 0.041
positive regulation of organelle organization GO:0010638 128 0.041
potassium ion transport GO:0006813 52 0.041
Human
positive regulation of cellular amine metabolic process GO:0033240 5 0.041
response to light stimulus GO:0009416 135 0.041
Human Yeast
regulation of glycogen metabolic process GO:0070873 13 0.041
negative regulation of nervous system development GO:0051961 156 0.041
synapse assembly GO:0007416 56 0.041
male gamete generation GO:0048232 285 0.041
regulation of cytoplasmic transport GO:1903649 112 0.040
Human Yeast
response to radiation GO:0009314 165 0.040
Human Yeast
positive regulation of cell cycle GO:0045787 92 0.040
protein localization to cell junction GO:1902414 3 0.040
branching morphogenesis of an epithelial tube GO:0048754 159 0.040
multi organism reproductive behavior GO:0044705 29 0.040
regulation of b cell activation GO:0050864 81 0.040
blood circulation GO:0008015 195 0.039
Mouse
innate immune response GO:0045087 157 0.039
ribonucleoside catabolic process GO:0042454 206 0.039
negative regulation of mapk cascade GO:0043409 65 0.039
Mouse
cell cell junction organization GO:0045216 72 0.039
Mouse
somatic cell dna recombination GO:0016444 51 0.039
lymphocyte activation involved in immune response GO:0002285 93 0.039
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.039
regulation of apoptotic signaling pathway GO:2001233 197 0.038
regulation of nuclear division GO:0051783 56 0.038
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.038
regulation of glucose transport GO:0010827 32 0.038
polysaccharide biosynthetic process GO:0000271 20 0.038
microtubule based process GO:0007017 236 0.038
ribonucleotide metabolic process GO:0009259 291 0.038
exocrine pancreas development GO:0031017 7 0.038
reproductive behavior GO:0019098 32 0.037
immunoglobulin production GO:0002377 73 0.037
cellular response to peptide GO:1901653 92 0.036
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.036
positive regulation of protein modification process GO:0031401 299 0.036
response to inorganic substance GO:0010035 96 0.036
heterocycle catabolic process GO:0046700 280 0.036
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.036
ear development GO:0043583 200 0.036
cation transmembrane transport GO:0098655 266 0.036
mrna processing GO:0006397 63 0.036
regulation of leukocyte differentiation GO:1902105 159 0.036
inflammatory response GO:0006954 244 0.035
neural retina development GO:0003407 41 0.035
neuron projection regeneration GO:0031102 14 0.035
neuromuscular process GO:0050905 99 0.035
cellularization GO:0007349 1 0.035
gland development GO:0048732 330 0.035
regulation of protein binding GO:0043393 60 0.034
regulation of epithelial cell proliferation GO:0050678 141 0.034
cellular response to biotic stimulus GO:0071216 92 0.034
chromosome segregation GO:0007059 48 0.034
ribonucleoprotein complex subunit organization GO:0071826 28 0.034
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.033
protein localization to membrane GO:0072657 108 0.033
transition metal ion homeostasis GO:0055076 54 0.033
regulation of lymphocyte activation GO:0051249 240 0.033
Mouse
negative regulation of b cell activation GO:0050869 27 0.033
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.033
negative regulation of cell proliferation GO:0008285 296 0.032
Mouse
negative regulation of glucose import GO:0046325 7 0.032
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.032
response to growth factor GO:0070848 198 0.032
tissue homeostasis GO:0001894 115 0.031
monosaccharide metabolic process GO:0005996 106 0.031
actin filament polymerization GO:0030041 44 0.031
heart process GO:0003015 94 0.031
negative regulation of lymphocyte proliferation GO:0050672 45 0.031
Mouse
ribose phosphate metabolic process GO:0019693 291 0.031
regulation of actin polymerization or depolymerization GO:0008064 45 0.030
negative regulation of cell cycle GO:0045786 123 0.030
molting cycle GO:0042303 90 0.030
nucleus localization GO:0051647 20 0.030
glycoprotein biosynthetic process GO:0009101 89 0.030
cellular carbohydrate metabolic process GO:0044262 119 0.030
calcium ion transmembrane transport GO:0070588 85 0.030
lymphocyte proliferation GO:0046651 164 0.030
Mouse
regulation of transferase activity GO:0051338 263 0.029
fatty acid biosynthetic process GO:0006633 41 0.029
Yeast
metaphase plate congression GO:0051310 2 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.029
nucleoside monophosphate metabolic process GO:0009123 85 0.029
regulation of cell division GO:0051302 76 0.029
negative regulation of wnt signaling pathway GO:0030178 73 0.029
cellular lipid metabolic process GO:0044255 323 0.028
Yeast
multi organism behavior GO:0051705 62 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
response to acid chemical GO:0001101 111 0.028
positive regulation of cellular catabolic process GO:0031331 148 0.028
Yeast
rna 3 end processing GO:0031123 20 0.028
organic anion transport GO:0015711 137 0.028
sulfur compound metabolic process GO:0006790 100 0.028
regulation of proteolysis GO:0030162 164 0.028
Yeast
feeding behavior GO:0007631 62 0.028
carbohydrate biosynthetic process GO:0016051 74 0.028
t cell anergy GO:0002870 4 0.028
Mouse
neural tube development GO:0021915 160 0.028
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.028
cellular response to acid chemical GO:0071229 68 0.028
negative regulation of cell cycle process GO:0010948 69 0.028
cardiac muscle cell contraction GO:0086003 7 0.028
neuron projection extension GO:1990138 64 0.027
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.027
negative regulation of dna replication GO:0008156 4 0.027
regulation of protein localization to nucleus GO:1900180 60 0.027
striated muscle contraction GO:0006941 45 0.027
mitochondrion distribution GO:0048311 4 0.027
hindbrain development GO:0030902 128 0.027
regulation of cell size GO:0008361 72 0.027
nucleoside triphosphate metabolic process GO:0009141 230 0.027
regulation of mapk cascade GO:0043408 248 0.027
Mouse
cellular response to inorganic substance GO:0071241 37 0.027
production of molecular mediator of immune response GO:0002440 103 0.027
digestive tract morphogenesis GO:0048546 147 0.027
regulation of ion homeostasis GO:2000021 64 0.027
positive regulation of protein export from nucleus GO:0046827 4 0.026
ensheathment of neurons GO:0007272 76 0.026
development of primary sexual characteristics GO:0045137 143 0.026
regulation of stress activated mapk cascade GO:0032872 69 0.026
Mouse
regulation of cell substrate adhesion GO:0010810 73 0.026
axon target recognition GO:0007412 4 0.026
regulation of organelle organization GO:0033043 289 0.026
Yeast
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.026
Yeast
regulation of glucose metabolic process GO:0010906 60 0.026
leukocyte migration GO:0050900 124 0.026
glycoprotein metabolic process GO:0009100 116 0.026
calcium ion homeostasis GO:0055074 127 0.026
positive regulation of transferase activity GO:0051347 167 0.026
regulation of striated muscle contraction GO:0006942 25 0.026
membrane organization GO:0061024 245 0.026
cellular polysaccharide biosynthetic process GO:0033692 19 0.026
synapse organization GO:0050808 125 0.026
positive regulation of mitotic cell cycle GO:0045931 41 0.026
positive regulation of kinase activity GO:0033674 155 0.026
transcription factor import into nucleus GO:0042991 26 0.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.025
regulation of cell growth GO:0001558 91 0.025
fatty acid metabolic process GO:0006631 121 0.025
Yeast
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 14 0.025
regulation of tight junction assembly GO:2000810 2 0.025
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.025
glial cell differentiation GO:0010001 131 0.024
organic acid biosynthetic process GO:0016053 86 0.024
Yeast
rna interference GO:0016246 2 0.024
negative regulation of ossification GO:0030279 49 0.024
Mouse
epithelial cell proliferation GO:0050673 174 0.024
carbohydrate transport GO:0008643 62 0.024
engulfment of apoptotic cell GO:0043652 3 0.024
regulation of protein ubiquitination GO:0031396 52 0.024
cellular modified amino acid metabolic process GO:0006575 63 0.024
maternal determination of anterior posterior axis embryo GO:0008358 2 0.024
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.024
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.024
morphogenesis of embryonic epithelium GO:0016331 159 0.024
regulation of inflammatory response GO:0050727 147 0.024
germline stem cell asymmetric division GO:0098728 2 0.024
neuromuscular process controlling balance GO:0050885 59 0.024
response to sterol GO:0036314 4 0.024
carboxylic acid biosynthetic process GO:0046394 86 0.024
Yeast
b cell differentiation GO:0030183 78 0.023
negative regulation of cell development GO:0010721 169 0.023
memory GO:0007613 58 0.023
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.023
cell junction organization GO:0034330 77 0.023
Mouse
steroid metabolic process GO:0008202 119 0.023
Yeast
regulation of cardiac muscle contraction GO:0055117 21 0.022
central nervous system neuron differentiation GO:0021953 162 0.022
protein localization to synapse GO:0035418 11 0.022
regulation of autophagic vacuole assembly GO:2000785 4 0.022
cytokine production GO:0001816 319 0.022
multicellular organismal reproductive behavior GO:0033057 23 0.022
embryonic epithelial tube formation GO:0001838 130 0.022
mating GO:0007618 27 0.022
nucleoside monophosphate catabolic process GO:0009125 59 0.022
positive regulation of transmembrane transport GO:0034764 29 0.022
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.022
divalent inorganic cation homeostasis GO:0072507 138 0.022
fertilization GO:0009566 127 0.022
clara cell differentiation GO:0060486 4 0.021
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.021
regulation of lymphocyte proliferation GO:0050670 117 0.021
Mouse
potassium ion transmembrane transport GO:0071805 43 0.021
Human
lymphocyte anergy GO:0002249 4 0.021
Mouse
myotube differentiation GO:0014902 105 0.021
neutral lipid metabolic process GO:0006638 57 0.021
ras protein signal transduction GO:0007265 77 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
regulation of kinase activity GO:0043549 249 0.021
neural tube formation GO:0001841 108 0.021
cellular potassium ion transport GO:0071804 43 0.021
Human
negative regulation of ligase activity GO:0051352 3 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
positive regulation of ion transport GO:0043270 65 0.020
Mouse
negative regulation of multi organism process GO:0043901 68 0.020
Mouse
regulation of cell migration GO:0030334 219 0.020
negative regulation of t cell proliferation GO:0042130 38 0.020
Mouse
actin filament organization GO:0007015 113 0.020
muscle tissue development GO:0060537 308 0.020
circulatory system process GO:0003013 197 0.020
Mouse
peripheral nervous system development GO:0007422 53 0.020
regulation of cytokine production GO:0001817 266 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
b cell activation involved in immune response GO:0002312 50 0.020
defense response to bacterium GO:0042742 119 0.020
rna localization GO:0006403 23 0.020
Yeast
regulation of response to wounding GO:1903034 189 0.020
cellular calcium ion homeostasis GO:0006874 119 0.020
regulation of feeding behavior GO:0060259 3 0.020
learning or memory GO:0007611 148 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
regulation of blood circulation GO:1903522 93 0.019
positive regulation of growth GO:0045927 104 0.019
sensory perception of sound GO:0007605 97 0.019
regulation of carbohydrate metabolic process GO:0006109 75 0.019

Nedd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.079
nervous system disease DOID:863 0 0.079
central nervous system disease DOID:331 0 0.079
disease of cellular proliferation DOID:14566 0 0.025
cancer DOID:162 0 0.025