Mus musculus

141 known processes

Phb2

prohibitin 2

(Aliases: Bcap37,REA,Bap37,AU044498,BAP)

Phb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.440
purine nucleotide metabolic process GO:0006163 302 0.343
Worm
regulation of mitochondrion organization GO:0010821 27 0.317
nucleotide metabolic process GO:0009117 332 0.289
Worm
mitochondrion organization GO:0007005 134 0.272
Worm
regulation of oxidative phosphorylation GO:0002082 6 0.247
Worm
nucleoside monophosphate metabolic process GO:0009123 85 0.227
Worm
nucleoside metabolic process GO:0009116 246 0.200
Worm
development of primary sexual characteristics GO:0045137 143 0.189
Worm
oxidation reduction process GO:0055114 342 0.186
positive regulation of mitochondrion organization GO:0010822 17 0.181
glycosyl compound metabolic process GO:1901657 246 0.172
Worm
purine nucleoside metabolic process GO:0042278 241 0.168
Worm
nucleoside phosphate metabolic process GO:0006753 338 0.152
Worm
cellular amino acid biosynthetic process GO:0008652 22 0.151
purine nucleoside monophosphate metabolic process GO:0009126 81 0.132
Worm
generation of precursor metabolites and energy GO:0006091 103 0.115
Worm
ribose phosphate metabolic process GO:0019693 291 0.113
Worm
purine ribonucleoside metabolic process GO:0046128 241 0.107
Worm
organophosphate biosynthetic process GO:0090407 122 0.106
mitochondrial transport GO:0006839 36 0.099
cytokine production GO:0001816 319 0.093
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.092
Worm
divalent inorganic cation homeostasis GO:0072507 138 0.090
ribonucleoside metabolic process GO:0009119 245 0.087
Worm
purine containing compound metabolic process GO:0072521 311 0.086
Worm
cation transport GO:0006812 399 0.083
nucleoside triphosphate metabolic process GO:0009141 230 0.077
Worm
purine nucleotide biosynthetic process GO:0006164 65 0.077
cellular nitrogen compound catabolic process GO:0044270 280 0.076
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.075
Worm
ribonucleoside monophosphate metabolic process GO:0009161 80 0.075
Worm
regulation of membrane potential GO:0042391 192 0.071
macromolecule catabolic process GO:0009057 281 0.071
organonitrogen compound biosynthetic process GO:1901566 192 0.066
mrna metabolic process GO:0016071 84 0.066
ion transmembrane transport GO:0034220 361 0.063
translation GO:0006412 93 0.063
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.061
nucleoside phosphate biosynthetic process GO:1901293 79 0.060
nucleotide biosynthetic process GO:0009165 78 0.060
response to oxygen levels GO:0070482 62 0.060
regulation of ion transport GO:0043269 215 0.058
ribonucleoprotein complex subunit organization GO:0071826 28 0.058
endocytosis GO:0006897 168 0.057
gland development GO:0048732 330 0.056
ribonucleotide metabolic process GO:0009259 291 0.056
Worm
atp metabolic process GO:0046034 75 0.055
Worm
proton transport GO:0015992 35 0.054
nucleobase containing small molecule metabolic process GO:0055086 352 0.053
Worm
heterocycle catabolic process GO:0046700 280 0.053
positive regulation of cytokine production GO:0001819 174 0.051
defecation GO:0030421 1 0.051
Worm
cellular response to cytokine stimulus GO:0071345 189 0.050
regulation of cellular ketone metabolic process GO:0010565 66 0.050
posttranscriptional regulation of gene expression GO:0010608 155 0.050
positive regulation of apoptotic process GO:0043065 217 0.043
nucleoside phosphate catabolic process GO:1901292 222 0.042
aromatic compound catabolic process GO:0019439 286 0.042
purine ribonucleoside catabolic process GO:0046130 205 0.041
cytoplasmic transport GO:0016482 234 0.041
amine metabolic process GO:0009308 45 0.041
positive regulation of protein modification process GO:0031401 299 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.040
cellular ion homeostasis GO:0006873 165 0.040
cellular ketone metabolic process GO:0042180 84 0.039
peptidyl amino acid modification GO:0018193 336 0.038
embryonic organ morphogenesis GO:0048562 276 0.038
nitrogen compound transport GO:0071705 271 0.038
cation transmembrane transport GO:0098655 266 0.038
intrinsic apoptotic signaling pathway GO:0097193 132 0.038
regulation of ion transmembrane transport GO:0034765 119 0.038
regulation of generation of precursor metabolites and energy GO:0043467 38 0.036
Worm
cellular amine metabolic process GO:0044106 44 0.036
response to oxidative stress GO:0006979 123 0.035
Worm
cytoplasmic translational initiation GO:0002183 3 0.035
regulation of cellular amino acid metabolic process GO:0006521 5 0.035
sensory perception GO:0007600 245 0.035
cellular homeostasis GO:0019725 240 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.034
carboxylic acid biosynthetic process GO:0046394 86 0.033
regulation of translation GO:0006417 71 0.033
purine containing compound catabolic process GO:0072523 213 0.033
positive regulation of programmed cell death GO:0043068 218 0.033
sodium ion transport GO:0006814 73 0.033
nucleoside triphosphate catabolic process GO:0009143 205 0.033
inorganic cation transmembrane transport GO:0098662 207 0.033
regulation of hydrolase activity GO:0051336 246 0.032
purine ribonucleotide biosynthetic process GO:0009152 59 0.032
gonad development GO:0008406 141 0.032
Worm
response to hypoxia GO:0001666 58 0.031
regulation of transporter activity GO:0032409 57 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.031
organic cyclic compound catabolic process GO:1901361 295 0.031
positive regulation of peptidase activity GO:0010952 49 0.030
regulation of defense response GO:0031347 233 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.029
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.029
regulation of nucleoside metabolic process GO:0009118 130 0.029
Worm
protein processing GO:0016485 163 0.028
purine containing compound biosynthetic process GO:0072522 70 0.027
cellular respiration GO:0045333 38 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
response to peptide hormone GO:0043434 127 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.025
apoptotic signaling pathway GO:0097190 306 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
calcium ion homeostasis GO:0055074 127 0.025
alpha amino acid biosynthetic process GO:1901607 15 0.025
small gtpase mediated signal transduction GO:0007264 97 0.025
positive regulation of innate immune response GO:0045089 80 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
proprioception GO:0019230 4 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.024
cellular macromolecule catabolic process GO:0044265 206 0.023
regulation of organelle organization GO:0033043 289 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.023
alpha amino acid metabolic process GO:1901605 59 0.022
immune response activating signal transduction GO:0002757 116 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
cellular metal ion homeostasis GO:0006875 151 0.022
ras protein signal transduction GO:0007265 77 0.022
protein maturation GO:0051604 176 0.022
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.022
regulation of transmembrane transport GO:0034762 128 0.021
metal ion homeostasis GO:0055065 189 0.021
organic acid biosynthetic process GO:0016053 86 0.021
positive regulation of cell death GO:0010942 224 0.021
rhythmic process GO:0048511 174 0.021
cellular response to dna damage stimulus GO:0006974 207 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
Worm
protein ubiquitination GO:0016567 171 0.021
protein acylation GO:0043543 64 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
Worm
cellular lipid metabolic process GO:0044255 323 0.020
germ cell development GO:0007281 185 0.020
Worm
regulation of lymphocyte activation GO:0051249 240 0.020
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
negative regulation of molecular function GO:0044092 258 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
organ growth GO:0035265 117 0.019
response to nutrient levels GO:0031667 109 0.019
regulation of ion transmembrane transporter activity GO:0032412 54 0.019
inflammatory response GO:0006954 244 0.018
organelle assembly GO:0070925 177 0.018
response to oxygen radical GO:0000305 16 0.018
leukocyte differentiation GO:0002521 342 0.017
homeostasis of number of cells GO:0048872 210 0.017
activation of innate immune response GO:0002218 56 0.017
immune effector process GO:0002252 321 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.016
cellular aldehyde metabolic process GO:0006081 12 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
ribose phosphate biosynthetic process GO:0046390 59 0.016
membrane organization GO:0061024 245 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.016
intracellular receptor signaling pathway GO:0030522 74 0.016
regulation of endopeptidase activity GO:0052548 89 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
Worm
response to extracellular stimulus GO:0009991 127 0.015
protein kinase b signaling GO:0043491 74 0.015
action potential GO:0001508 78 0.015
urogenital system development GO:0001655 261 0.015
cellular amino acid metabolic process GO:0006520 103 0.015
rna splicing via transesterification reactions GO:0000375 43 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
hydrogen transport GO:0006818 35 0.015
response to decreased oxygen levels GO:0036293 59 0.015
dna dealkylation GO:0035510 11 0.014
cellular response to extracellular stimulus GO:0031668 81 0.014
purine nucleoside biosynthetic process GO:0042451 19 0.014
divalent metal ion transport GO:0070838 172 0.014
peptidyl lysine modification GO:0018205 77 0.014
multi multicellular organism process GO:0044706 109 0.014
protein modification by small protein conjugation GO:0032446 187 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
heart morphogenesis GO:0003007 178 0.013
nucleotide catabolic process GO:0009166 217 0.013
mitochondrial translation GO:0032543 4 0.013
regulation of hormone levels GO:0010817 211 0.013
regulation of peptidase activity GO:0052547 96 0.013
protein polymerization GO:0051258 57 0.013
multicellular organismal signaling GO:0035637 91 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
positive regulation of cell development GO:0010720 237 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
regulation of protein kinase b signaling GO:0051896 56 0.013
regulation of mrna metabolic process GO:1903311 43 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.012
locomotory behavior GO:0007626 195 0.012
oogenesis GO:0048477 56 0.012
Worm
energy derivation by oxidation of organic compounds GO:0015980 77 0.012
positive regulation of proteolysis GO:0045862 85 0.012
receptor mediated endocytosis GO:0006898 51 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
response to organonitrogen compound GO:0010243 246 0.012
adult behavior GO:0030534 135 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
response to organic cyclic compound GO:0014070 198 0.012
rna catabolic process GO:0006401 29 0.012
oxidative phosphorylation GO:0006119 14 0.012
Worm
cellular modified amino acid biosynthetic process GO:0042398 12 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
Worm
ovulation cycle GO:0042698 59 0.011
response to reactive oxygen species GO:0000302 56 0.011
small molecule catabolic process GO:0044282 71 0.011
regulation of rna splicing GO:0043484 37 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.011
calcium ion transport GO:0006816 159 0.011
epithelial cell proliferation GO:0050673 174 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
myeloid leukocyte migration GO:0097529 57 0.011
t cell differentiation GO:0030217 174 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
single organism cell adhesion GO:0098602 156 0.011
organelle fusion GO:0048284 28 0.011
regulation of cellular response to stress GO:0080135 159 0.011
mrna processing GO:0006397 63 0.011
protein catabolic process GO:0030163 221 0.011
regulation of cell activation GO:0050865 289 0.011
regulation of sarcomere organization GO:0060297 4 0.011
regulation of cytokine production GO:0001817 266 0.010
purine ribonucleoside biosynthetic process GO:0046129 19 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
regulation of dendritic cell chemotaxis GO:2000508 1 0.010
male gamete generation GO:0048232 285 0.010
Worm
response to superoxide GO:0000303 16 0.010
g protein coupled receptor signaling pathway GO:0007186 243 0.010
activation of mapk activity GO:0000187 59 0.010
regulation of anion transport GO:0044070 27 0.010
hydrogen ion transmembrane transport GO:1902600 25 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010

Phb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.234
disease of anatomical entity DOID:7 0 0.234
central nervous system disease DOID:331 0 0.234
neurodegenerative disease DOID:1289 0 0.011