Mus musculus

148 known processes

Plin5

perilipin 5

(Aliases: 2310076L09Rik,Lsdp5,AW109675,AI415325,MLDP,PAT-1)

Plin5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of sequestering of triglyceride GO:0010889 6 0.816
positive regulation of triglyceride catabolic process GO:0010898 3 0.509
positive regulation of triglyceride metabolic process GO:0090208 9 0.484
sequestering of triglyceride GO:0030730 6 0.475
regulation of triglyceride catabolic process GO:0010896 5 0.328
cellular lipid metabolic process GO:0044255 323 0.265
glycerolipid catabolic process GO:0046503 16 0.261
acylglycerol metabolic process GO:0006639 55 0.235
regulation of triglyceride metabolic process GO:0090207 17 0.222
acyl coa metabolic process GO:0006637 19 0.185
neutral lipid metabolic process GO:0006638 57 0.180
lipid storage GO:0019915 36 0.173
neutral lipid catabolic process GO:0046461 11 0.153
positive regulation of sequestering of triglyceride GO:0010890 4 0.148
regulation of lipid catabolic process GO:0050994 15 0.148
coenzyme metabolic process GO:0006732 52 0.146
amine metabolic process GO:0009308 45 0.128
positive regulation of cellular catabolic process GO:0031331 148 0.121
lipid biosynthetic process GO:0008610 179 0.121
regulation of lipoprotein lipase activity GO:0051004 4 0.117
thioester metabolic process GO:0035383 19 0.115
positive regulation of lipoprotein lipase activity GO:0051006 3 0.114
acylglycerol catabolic process GO:0046464 11 0.114
monocarboxylic acid metabolic process GO:0032787 191 0.113
organic acid biosynthetic process GO:0016053 86 0.109
cofactor metabolic process GO:0051186 80 0.107
regulation of lipid storage GO:0010883 20 0.101
regulation of cellular catabolic process GO:0031329 242 0.100
diacylglycerol biosynthetic process GO:0006651 2 0.093
carbohydrate metabolic process GO:0005975 230 0.091
glycerolipid metabolic process GO:0046486 122 0.091
positive regulation of triglyceride lipase activity GO:0061365 3 0.087
lipid catabolic process GO:0016042 69 0.087
organic hydroxy compound metabolic process GO:1901615 203 0.085
synaptic transmission GO:0007268 329 0.078
regulation of lipid metabolic process GO:0019216 118 0.078
cellular ketone metabolic process GO:0042180 84 0.078
small molecule catabolic process GO:0044282 71 0.074
cellular macromolecule catabolic process GO:0044265 206 0.073
small molecule biosynthetic process GO:0044283 132 0.072
maintenance of location GO:0051235 89 0.071
cellular amino acid metabolic process GO:0006520 103 0.069
brown fat cell differentiation GO:0050873 36 0.067
regulation of fatty acid oxidation GO:0046320 10 0.067
regulation of cellular amino acid metabolic process GO:0006521 5 0.066
fatty acid metabolic process GO:0006631 121 0.063
lipid particle organization GO:0034389 7 0.063
nucleobase containing small molecule metabolic process GO:0055086 352 0.063
regulation of cellular amine metabolic process GO:0033238 20 0.058
regulation of hormone levels GO:0010817 211 0.056
heterocycle catabolic process GO:0046700 280 0.054
positive regulation of lipid metabolic process GO:0045834 40 0.054
mapk cascade GO:0000165 281 0.053
cellular amine metabolic process GO:0044106 44 0.053
regulation of membrane potential GO:0042391 192 0.053
purine containing compound metabolic process GO:0072521 311 0.051
spermatogenesis GO:0007283 284 0.051
organonitrogen compound biosynthetic process GO:1901566 192 0.050
cellular lipid catabolic process GO:0044242 52 0.049
triglyceride metabolic process GO:0006641 51 0.048
aromatic compound catabolic process GO:0019439 286 0.048
positive regulation of lipid storage GO:0010884 10 0.048
lipid homeostasis GO:0055088 63 0.047
regulation of hydrolase activity GO:0051336 246 0.047
positive regulation of glycolytic process GO:0045821 4 0.047
cellular chemical homeostasis GO:0055082 215 0.046
glycerolipid biosynthetic process GO:0045017 50 0.045
macromolecule catabolic process GO:0009057 281 0.043
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.043
regulation of circadian sleep wake cycle GO:0042749 3 0.042
cellular homeostasis GO:0019725 240 0.042
cellular nitrogen compound catabolic process GO:0044270 280 0.042
ribonucleoside metabolic process GO:0009119 245 0.041
organic acid transport GO:0015849 101 0.041
cation transport GO:0006812 399 0.039
organic cyclic compound catabolic process GO:1901361 295 0.039
multicellular organismal homeostasis GO:0048871 164 0.038
cation homeostasis GO:0055080 212 0.037
purine nucleoside metabolic process GO:0042278 241 0.036
small gtpase mediated signal transduction GO:0007264 97 0.036
oxidation reduction process GO:0055114 342 0.036
regulation of kinase activity GO:0043549 249 0.036
acylglycerol biosynthetic process GO:0046463 18 0.036
peptidyl amino acid modification GO:0018193 336 0.035
ion transmembrane transport GO:0034220 361 0.034
blood circulation GO:0008015 195 0.034
metal ion homeostasis GO:0055065 189 0.033
positive regulation of hydrolase activity GO:0051345 148 0.033
regulation of transferase activity GO:0051338 263 0.033
action potential GO:0001508 78 0.033
carboxylic acid biosynthetic process GO:0046394 86 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
cellular carbohydrate metabolic process GO:0044262 119 0.032
diacylglycerol metabolic process GO:0046339 6 0.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.031
g protein coupled receptor signaling pathway GO:0007186 243 0.030
long chain fatty acid import GO:0044539 2 0.030
cellular metal ion homeostasis GO:0006875 151 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
transmembrane transport GO:0055085 412 0.030
sterol homeostasis GO:0055092 45 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
cation transmembrane transport GO:0098655 266 0.029
microtubule based process GO:0007017 236 0.028
steroid metabolic process GO:0008202 119 0.028
cytoplasmic transport GO:0016482 234 0.028
response to nutrient levels GO:0031667 109 0.028
energy derivation by oxidation of organic compounds GO:0015980 77 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
alpha amino acid metabolic process GO:1901605 59 0.026
fatty acid oxidation GO:0019395 28 0.026
epithelial cell proliferation GO:0050673 174 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.025
anion transport GO:0006820 177 0.025
regulation of carbohydrate metabolic process GO:0006109 75 0.025
monosaccharide metabolic process GO:0005996 106 0.025
heart contraction GO:0060047 93 0.025
nitrogen compound transport GO:0071705 271 0.025
potassium ion transport GO:0006813 52 0.025
thioester biosynthetic process GO:0035384 7 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
negative regulation of sequestering of triglyceride GO:0010891 2 0.024
microtubule cytoskeleton organization GO:0000226 157 0.024
response to radiation GO:0009314 165 0.024
protein localization to organelle GO:0033365 185 0.024
cellular protein catabolic process GO:0044257 155 0.024
carbohydrate biosynthetic process GO:0016051 74 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.024
regulation of cellular ketone metabolic process GO:0010565 66 0.024
regulation of system process GO:0044057 200 0.023
response to organic cyclic compound GO:0014070 198 0.023
response to peptide hormone GO:0043434 127 0.023
positive regulation of lipid catabolic process GO:0050996 6 0.023
nucleoside phosphate biosynthetic process GO:1901293 79 0.023
intracellular protein transport GO:0006886 204 0.023
response to organonitrogen compound GO:0010243 246 0.022
carboxylic acid catabolic process GO:0046395 51 0.022
regulation of fatty acid metabolic process GO:0019217 28 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
ribose phosphate biosynthetic process GO:0046390 59 0.022
monocarboxylic acid catabolic process GO:0072329 27 0.022
cholesterol metabolic process GO:0008203 56 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.021
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.021
positive regulation of mapk cascade GO:0043410 170 0.021
regulation of organelle organization GO:0033043 289 0.021
negative regulation of execution phase of apoptosis GO:1900118 4 0.021
response to extracellular stimulus GO:0009991 127 0.021
multi multicellular organism process GO:0044706 109 0.020
forebrain development GO:0030900 302 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
lipid localization GO:0010876 126 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
alcohol metabolic process GO:0006066 116 0.019
negative regulation of lipid storage GO:0010888 6 0.019
fat cell differentiation GO:0045444 160 0.019
apoptotic signaling pathway GO:0097190 306 0.019
organic anion transport GO:0015711 137 0.019
vascular process in circulatory system GO:0003018 62 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
multicellular organismal signaling GO:0035637 91 0.019
striated muscle contraction GO:0006941 45 0.019
conditioned taste aversion GO:0001661 4 0.019
regulation of protein localization GO:0032880 231 0.019
response to light stimulus GO:0009416 135 0.019
carbohydrate catabolic process GO:0016052 32 0.019
protein ubiquitination GO:0016567 171 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
nucleotide metabolic process GO:0009117 332 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
pyruvate metabolic process GO:0006090 28 0.018
germ cell development GO:0007281 185 0.018
regulation of blood pressure GO:0008217 93 0.018
triglyceride mobilization GO:0006642 5 0.018
c4 dicarboxylate transport GO:0015740 3 0.018
organ regeneration GO:0031100 2 0.018
muscle contraction GO:0006936 101 0.018
lipid transport GO:0006869 98 0.018
fat soluble vitamin biosynthetic process GO:0042362 4 0.018
amide transport GO:0042886 138 0.018
regulation of renal sodium excretion GO:0035813 3 0.018
ribonucleoside bisphosphate metabolic process GO:0033875 9 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
regulation of lipid biosynthetic process GO:0046890 54 0.017
regulation of cell migration GO:0030334 219 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
fatty acid biosynthetic process GO:0006633 41 0.017
heart process GO:0003015 94 0.017
sterol metabolic process GO:0016125 58 0.017
negative regulation of molecular function GO:0044092 258 0.017
regulation of homeostatic process GO:0032844 182 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
purine nucleotide biosynthetic process GO:0006164 65 0.017
hormone secretion GO:0046879 128 0.017
cardiac muscle contraction GO:0060048 32 0.017
regulation of circadian rhythm GO:0042752 58 0.017
protein catabolic process GO:0030163 221 0.017
neuron neuron synaptic transmission GO:0007270 69 0.017
circulatory system process GO:0003013 197 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
amino acid betaine metabolic process GO:0006577 7 0.016
very long chain fatty acid metabolic process GO:0000038 8 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
regulation of feeding behavior GO:0060259 3 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
nucleoside bisphosphate metabolic process GO:0033865 9 0.016
peptide transport GO:0015833 133 0.016
rho protein signal transduction GO:0007266 32 0.016
cholesterol homeostasis GO:0042632 44 0.016
cellular protein complex assembly GO:0043623 116 0.016
organelle localization GO:0051640 179 0.016
protein targeting GO:0006605 143 0.016
response to lipopolysaccharide GO:0032496 128 0.016
regulation of transmembrane transport GO:0034762 128 0.016
fatty acid catabolic process GO:0009062 25 0.016
organonitrogen compound catabolic process GO:1901565 264 0.015
cellular modified amino acid metabolic process GO:0006575 63 0.015
learning or memory GO:0007611 148 0.015
protein localization to nucleus GO:0034504 121 0.015
intracellular receptor signaling pathway GO:0030522 74 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
fatty acyl coa metabolic process GO:0035337 4 0.015
monosaccharide transport GO:0015749 58 0.015
regulation of actin filament based process GO:0032970 99 0.015
glucose homeostasis GO:0042593 128 0.015
rhythmic process GO:0048511 174 0.015
detection of abiotic stimulus GO:0009582 60 0.015
lipid modification GO:0030258 65 0.015
positive regulation of protein modification process GO:0031401 299 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
inflammatory response GO:0006954 244 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
positive regulation of cell activation GO:0050867 158 0.015
calcium ion homeostasis GO:0055074 127 0.015
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
endomembrane system organization GO:0010256 147 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
detection of external stimulus GO:0009581 61 0.014
organelle fission GO:0048285 170 0.014
organic hydroxy compound transport GO:0015850 93 0.014
protein import GO:0017038 101 0.014
regulation of appetite GO:0032098 12 0.014
coenzyme biosynthetic process GO:0009108 23 0.014
renal sodium excretion GO:0035812 3 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
regulation of cell motility GO:2000145 236 0.014
locomotory behavior GO:0007626 195 0.014
saturated monocarboxylic acid metabolic process GO:0032788 2 0.014
negative regulation of lipid metabolic process GO:0045833 30 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
glucose metabolic process GO:0006006 92 0.014
sulfur compound metabolic process GO:0006790 100 0.014
muscle system process GO:0003012 141 0.014
monocarboxylic acid transport GO:0015718 44 0.014
nucleoside catabolic process GO:0009164 206 0.014
purine containing compound catabolic process GO:0072523 213 0.014
endocytosis GO:0006897 168 0.013
adiponectin activated signaling pathway GO:0033211 4 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
actin cytoskeleton organization GO:0030036 220 0.013
fatty acid transmembrane transport GO:1902001 1 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
nuclear import GO:0051170 95 0.013
regulation of t cell activation GO:0050863 170 0.013
response to growth factor GO:0070848 198 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.013
single organism nuclear import GO:1902593 95 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
intestinal absorption GO:0050892 13 0.013
metencephalon development GO:0022037 89 0.013
cellular ion homeostasis GO:0006873 165 0.013
skeletal system development GO:0001501 356 0.013
regulation of cell activation GO:0050865 289 0.013
serine family amino acid metabolic process GO:0009069 7 0.013
regulation of phospholipid biosynthetic process GO:0071071 3 0.013
long chain fatty acid metabolic process GO:0001676 26 0.013
ossification GO:0001503 216 0.013
meiotic cell cycle GO:0051321 122 0.013
ameboidal type cell migration GO:0001667 128 0.013
rna interference GO:0016246 2 0.013
negative regulation of organelle organization GO:0010639 90 0.013
positive regulation of cell death GO:0010942 224 0.013
hormone metabolic process GO:0042445 86 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
lipid oxidation GO:0034440 29 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
cognition GO:0050890 149 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.012
transition metal ion homeostasis GO:0055076 54 0.012
exocytosis GO:0006887 121 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
regulation of cell cycle GO:0051726 281 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
detection of stimulus GO:0051606 84 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
male gamete generation GO:0048232 285 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
positive regulation of kinase activity GO:0033674 155 0.012
myeloid cell differentiation GO:0030099 233 0.012
very long chain fatty acid catabolic process GO:0042760 2 0.012
regulation of inflammatory response GO:0050727 147 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
regulation of systemic arterial blood pressure GO:0003073 61 0.012
membrane organization GO:0061024 245 0.012
muscle cell differentiation GO:0042692 261 0.012
regulation of action potential GO:0098900 4 0.012
carboxylic acid transport GO:0046942 100 0.012
negative regulation of kinase activity GO:0033673 81 0.012
regulation of cell projection organization GO:0031344 206 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
digestive tract development GO:0048565 190 0.012
fertilization GO:0009566 127 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
g protein coupled receptor internalization GO:0002031 3 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
regulation of cellular response to stress GO:0080135 159 0.012
regulation of muscle system process GO:0090257 80 0.012
negative regulation of blood pressure GO:0045776 22 0.011
regulation of peptide secretion GO:0002791 77 0.011
ribonucleotide biosynthetic process GO:0009260 59 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
positive regulation of cell development GO:0010720 237 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
response to hyperoxia GO:0055093 2 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
insulin secretion GO:0030073 89 0.011
acetyl coa metabolic process GO:0006084 8 0.011
skin development GO:0043588 220 0.011
meiotic nuclear division GO:0007126 115 0.011
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.011
positive regulation of cell migration GO:0030335 109 0.011
response to vitamin a GO:0033189 1 0.011
triglyceride biosynthetic process GO:0019432 17 0.011
circadian regulation of gene expression GO:0032922 48 0.011
succinyl coa metabolic process GO:0006104 1 0.011
neuronal action potential GO:0019228 54 0.011
regulation of peptide transport GO:0090087 91 0.011
asymmetric stem cell division GO:0098722 3 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
molting cycle GO:0042303 90 0.011
carbohydrate homeostasis GO:0033500 128 0.011
neutral lipid biosynthetic process GO:0046460 18 0.011
spermatid development GO:0007286 108 0.011
nucleotide catabolic process GO:0009166 217 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
regulation of ion transport GO:0043269 215 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
regulation of glycogen catabolic process GO:0005981 2 0.011
limb development GO:0060173 166 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
regulation of cellular component size GO:0032535 121 0.011
dna metabolic process GO:0006259 303 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
intracellular mrna localization GO:0008298 4 0.011
regulation of cytokine production GO:0001817 266 0.011
t cell activation GO:0042110 289 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.010
habituation GO:0046959 3 0.010
epidermis development GO:0008544 187 0.010
respiratory tube development GO:0030323 167 0.010
iron ion homeostasis GO:0055072 36 0.010
monocarboxylic acid biosynthetic process GO:0072330 61 0.010
multicellular organismal response to stress GO:0033555 62 0.010
positive regulation of t cell activation GO:0050870 101 0.010
regulation of protein catabolic process GO:0042176 108 0.010
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.010
positive regulation of cardiac muscle contraction GO:0060452 2 0.010
regulation of lipase activity GO:0060191 15 0.010
positive regulation of cell motility GO:2000147 116 0.010
mitotic cell cycle process GO:1903047 159 0.010
sensory organ morphogenesis GO:0090596 242 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
i kappab kinase nf kappab signaling GO:0007249 85 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.010
negative regulation of cell cycle GO:0045786 123 0.010
spermatid differentiation GO:0048515 115 0.010
norepinephrine secretion GO:0048243 2 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
cellular amino acid catabolic process GO:0009063 25 0.010
striated muscle tissue development GO:0014706 293 0.010

Plin5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.034
nervous system disease DOID:863 0 0.033
disease of anatomical entity DOID:7 0 0.033
sensory system disease DOID:0050155 0 0.014
central nervous system disease DOID:331 0 0.012
eye and adnexa disease DOID:1492 0 0.011
cardiovascular system disease DOID:1287 0 0.011