Mus musculus

8 known processes

Timp3

tissue inhibitor of metalloproteinase 3

(Aliases: Timp-3)

Timp3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
angiogenesis GO:0001525 201 0.806
amine metabolic process GO:0009308 45 0.774
negative regulation of protein metabolic process GO:0051248 282 0.724
Human Mouse Rat Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.630
regulation of cellular ketone metabolic process GO:0010565 66 0.597
cellular amine metabolic process GO:0044106 44 0.580
respiratory tube development GO:0030323 167 0.556
cellular amino acid metabolic process GO:0006520 103 0.532
blood vessel morphogenesis GO:0048514 285 0.513
regulation of cellular amine metabolic process GO:0033238 20 0.491
regulation of cell motility GO:2000145 236 0.441
protein catabolic process GO:0030163 221 0.423
Human
cellular ketone metabolic process GO:0042180 84 0.392
peptidyl tyrosine phosphorylation GO:0018108 143 0.382
muscle tissue development GO:0060537 308 0.343
skeletal muscle organ development GO:0060538 163 0.342
cytokine mediated signaling pathway GO:0019221 115 0.338
cell chemotaxis GO:0060326 81 0.332
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.327
regulation of kinase activity GO:0043549 249 0.321
peptidyl amino acid modification GO:0018193 336 0.318
regulation of cell migration GO:0030334 219 0.315
mapk cascade GO:0000165 281 0.314
Mouse
macromolecule catabolic process GO:0009057 281 0.312
Human
urogenital system development GO:0001655 261 0.306
positive regulation of mapk cascade GO:0043410 170 0.303
respiratory system development GO:0060541 190 0.291
Fly
oxidation reduction process GO:0055114 342 0.275
positive regulation of cellular amine metabolic process GO:0033240 5 0.275
protein kinase b signaling GO:0043491 74 0.266
single organism cell adhesion GO:0098602 156 0.264
Fly
leukocyte migration GO:0050900 124 0.263
neuron projection guidance GO:0097485 141 0.261
extracellular matrix organization GO:0030198 147 0.260
Fly
gland development GO:0048732 330 0.256
response to retinoic acid GO:0032526 56 0.250
positive regulation of cell migration GO:0030335 109 0.246
negative regulation of molecular function GO:0044092 258 0.235
Mouse Fly
regulation of protein kinase activity GO:0045859 232 0.235
positive regulation of protein modification process GO:0031401 299 0.233
response to oxidative stress GO:0006979 123 0.229
digestive system development GO:0055123 200 0.223
axon guidance GO:0007411 141 0.219
fat cell differentiation GO:0045444 160 0.212
regulation of transferase activity GO:0051338 263 0.211
chemotaxis GO:0006935 247 0.210
renal system development GO:0072001 225 0.210
cellular response to cytokine stimulus GO:0071345 189 0.210
digestive tract development GO:0048565 190 0.204
lung development GO:0030324 164 0.200
regulation of microvillus assembly GO:0032534 3 0.196
liver development GO:0001889 66 0.193
regulation of mapk cascade GO:0043408 248 0.192
Mouse
circulatory system process GO:0003013 197 0.190
camera type eye development GO:0043010 266 0.188
blood circulation GO:0008015 195 0.187
extracellular structure organization GO:0043062 148 0.184
Fly
regulation of system process GO:0044057 200 0.183
positive regulation of programmed cell death GO:0043068 218 0.179
negative regulation of cellular protein metabolic process GO:0032269 247 0.174
Human Mouse Rat Fly
cell adhesion GO:0007155 329 0.173
Fly
rhythmic process GO:0048511 174 0.168
transmission of nerve impulse GO:0019226 76 0.165
positive regulation of apoptotic process GO:0043065 217 0.163
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.162
regulation of fat cell differentiation GO:0045598 81 0.156
kidney development GO:0001822 213 0.154
negative regulation of endothelial cell migration GO:0010596 4 0.152
response to organic cyclic compound GO:0014070 198 0.151
Rat
regulation of protein localization GO:0032880 231 0.148
negative regulation of cellular amine metabolic process GO:0033239 1 0.148
organonitrogen compound biosynthetic process GO:1901566 192 0.147
positive regulation of cell death GO:0010942 224 0.147
regulation of apoptotic signaling pathway GO:2001233 197 0.147
positive regulation of kinase activity GO:0033674 155 0.139
glial cell differentiation GO:0010001 131 0.139
striated muscle tissue development GO:0014706 293 0.137
single organismal cell cell adhesion GO:0016337 131 0.136
Fly
small gtpase mediated signal transduction GO:0007264 97 0.133
multicellular organism growth GO:0035264 161 0.133
regulation of cellular component biogenesis GO:0044087 181 0.131
digestive tract morphogenesis GO:0048546 147 0.130
inflammatory response GO:0006954 244 0.130
positive regulation of protein kinase activity GO:0045860 144 0.129
developmental maturation GO:0021700 193 0.127
regulation of microvillus organization GO:0032530 3 0.125
negative regulation of intracellular signal transduction GO:1902532 167 0.124
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.124
skeletal system development GO:0001501 356 0.121
response to growth factor GO:0070848 198 0.119
glomerulus development GO:0032835 40 0.119
cellular response to organic cyclic compound GO:0071407 87 0.119
cellular response to growth factor stimulus GO:0071363 197 0.117
negative regulation of protein phosphorylation GO:0001933 126 0.114
leukocyte chemotaxis GO:0030595 69 0.110
developmental growth involved in morphogenesis GO:0060560 138 0.109
Fly
apoptotic signaling pathway GO:0097190 306 0.109
regulation of protein kinase b signaling GO:0051896 56 0.108
regulation of peptidase activity GO:0052547 96 0.107
Mouse Fly
regulation of cellular response to stress GO:0080135 159 0.105
axonogenesis GO:0007409 274 0.105
epithelial cell migration GO:0010631 63 0.105
regulation of cell projection organization GO:0031344 206 0.101
response to oxygen levels GO:0070482 62 0.101
negative regulation of cell proliferation GO:0008285 296 0.101
Mouse
defense response to other organism GO:0098542 197 0.101
ameboidal type cell migration GO:0001667 128 0.098
embryonic organ morphogenesis GO:0048562 276 0.097
positive regulation of protein kinase b signaling GO:0051897 32 0.097
forebrain development GO:0030900 302 0.096
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.096
maintenance of location GO:0051235 89 0.096
response to radiation GO:0009314 165 0.096
Fly
regulation of actin filament based process GO:0032970 99 0.096
morphogenesis of a branching epithelium GO:0061138 193 0.095
negative regulation of phosphorus metabolic process GO:0010563 184 0.093
regulation of epithelial cell migration GO:0010632 35 0.090
ras protein signal transduction GO:0007265 77 0.089
negative regulation of cell motility GO:2000146 61 0.088
engulfment of apoptotic cell GO:0043652 3 0.087
cerebral cortex radially oriented cell migration GO:0021799 31 0.087
negative regulation of immune system process GO:0002683 209 0.086
heart morphogenesis GO:0003007 178 0.086
nucleobase containing small molecule metabolic process GO:0055086 352 0.085
Mouse
epidermis development GO:0008544 187 0.085
positive regulation of proteolysis GO:0045862 85 0.085
cellular response to oxidative stress GO:0034599 76 0.084
sphingolipid metabolic process GO:0006665 45 0.083
response to amino acid GO:0043200 37 0.083
Rat
morphogenesis of a branching structure GO:0001763 203 0.083
cellular response to fluid shear stress GO:0071498 4 0.083
erythrocyte differentiation GO:0030218 88 0.082
negative regulation of cell migration GO:0030336 59 0.082
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.081
peptidyl tyrosine modification GO:0018212 145 0.081
rho protein signal transduction GO:0007266 32 0.080
response to hypoxia GO:0001666 58 0.080
cellular response to hormone stimulus GO:0032870 150 0.079
cell differentiation involved in kidney development GO:0061005 33 0.078
nuclear transport GO:0051169 139 0.078
epithelium migration GO:0090132 63 0.074
dendrite development GO:0016358 115 0.073
regulation of removal of superoxide radicals GO:2000121 4 0.073
negative regulation of protein modification process GO:0031400 163 0.072
forebrain cell migration GO:0021885 58 0.072
regulation of sphingolipid mediated signaling pathway GO:1902068 2 0.070
response to reactive oxygen species GO:0000302 56 0.070
epithelial cell differentiation involved in kidney development GO:0035850 23 0.069
regulation of actin cytoskeleton organization GO:0032956 84 0.069
positive regulation of nervous system development GO:0051962 221 0.069
organ growth GO:0035265 117 0.069
positive regulation of cell motility GO:2000147 116 0.067
epithelial tube morphogenesis GO:0060562 303 0.067
response to inorganic substance GO:0010035 96 0.066
muscle system process GO:0003012 141 0.066
regulation of hormone levels GO:0010817 211 0.065
glucose transport GO:0015758 56 0.065
hexose transport GO:0008645 56 0.065
connective tissue development GO:0061448 179 0.064
elastic fiber assembly GO:0048251 4 0.064
cell matrix adhesion GO:0007160 68 0.063
regulation of cytokine production GO:0001817 266 0.063
regulation of defense response GO:0031347 233 0.062
regulation of hydrolase activity GO:0051336 246 0.062
Mouse Fly
myeloid leukocyte migration GO:0097529 57 0.062
regulation of cell cycle process GO:0010564 160 0.061
trabecula morphogenesis GO:0061383 40 0.061
regulation of endopeptidase activity GO:0052548 89 0.061
Mouse Fly
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.060
antibacterial peptide secretion GO:0002779 1 0.060
protein maturation GO:0051604 176 0.060
Human Mouse Rat Fly
positive regulation of cell substrate adhesion GO:0010811 47 0.060
protein localization to nucleus GO:0034504 121 0.060
vascular process in circulatory system GO:0003018 62 0.059
cell migration involved in gastrulation GO:0042074 13 0.059
ensheathment of neurons GO:0007272 76 0.059
cerebral cortex cell migration GO:0021795 44 0.058
epithelial cell development GO:0002064 159 0.058
canonical wnt signaling pathway GO:0060070 130 0.058
defense response to bacterium GO:0042742 119 0.058
stem cell differentiation GO:0048863 268 0.057
telencephalon cell migration GO:0022029 55 0.057
cellular response to lipid GO:0071396 145 0.057
membrane organization GO:0061024 245 0.056
regulation of map kinase activity GO:0043405 120 0.056
positive regulation of cell projection organization GO:0031346 95 0.055
negative regulation of hydrolase activity GO:0051346 71 0.055
Mouse Fly
circadian regulation of gene expression GO:0032922 48 0.055
cellular response to steroid hormone stimulus GO:0071383 33 0.055
phospholipid metabolic process GO:0006644 87 0.054
regulation of cell activation GO:0050865 289 0.054
energy derivation by oxidation of organic compounds GO:0015980 77 0.054
anion transport GO:0006820 177 0.053
cell maturation GO:0048469 127 0.053
tissue homeostasis GO:0001894 115 0.053
response to organonitrogen compound GO:0010243 246 0.052
Rat
establishment of tissue polarity GO:0007164 28 0.051
positive regulation of protein phosphorylation GO:0001934 242 0.051
regulation of cell cycle GO:0051726 281 0.050
response to peptide GO:1901652 136 0.050
skin development GO:0043588 220 0.050
anatomical structure homeostasis GO:0060249 145 0.050
cellular homeostasis GO:0019725 240 0.049
protein localization to membrane GO:0072657 108 0.049
positive regulation of cell development GO:0010720 237 0.049
response to drug GO:0042493 75 0.049
lipid localization GO:0010876 126 0.048
glomerular epithelial cell differentiation GO:0072311 10 0.048
regulation of plasma lipoprotein particle levels GO:0097006 23 0.047
peptide metabolic process GO:0006518 46 0.047
embryonic epithelial tube formation GO:0001838 130 0.046
endothelial cell migration GO:0043542 44 0.046
cytoplasmic transport GO:0016482 234 0.046
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.046
regulation of lymphocyte activation GO:0051249 240 0.046
lung alveolus development GO:0048286 45 0.046
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.046
regulation of establishment of planar polarity GO:0090175 28 0.046
myeloid cell differentiation GO:0030099 233 0.046
positive regulation of lipid biosynthetic process GO:0046889 18 0.045
negative regulation of cellular component organization GO:0051129 194 0.045
basement membrane organization GO:0071711 8 0.045
Fly
negative regulation of defense response GO:0031348 77 0.045
layer formation in cerebral cortex GO:0021819 13 0.045
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.045
locomotory behavior GO:0007626 195 0.045
regulation of cellular response to growth factor stimulus GO:0090287 82 0.044
transmembrane transport GO:0055085 412 0.044
cellular amide metabolic process GO:0043603 58 0.044
tissue remodeling GO:0048771 102 0.044
organic anion transport GO:0015711 137 0.043
multi multicellular organism process GO:0044706 109 0.043
sterol homeostasis GO:0055092 45 0.043
multicellular organismal homeostasis GO:0048871 164 0.043
regulation of body fluid levels GO:0050878 162 0.042
regulation of organ morphogenesis GO:2000027 144 0.042
hepaticobiliary system development GO:0061008 67 0.042
lipid homeostasis GO:0055088 63 0.041
single organism nuclear import GO:1902593 95 0.041
ovarian follicle development GO:0001541 40 0.041
regulation of neuron projection development GO:0010975 169 0.041
positive regulation of cardiac muscle contraction GO:0060452 2 0.041
metanephric glomerular visceral epithelial cell development GO:0072249 2 0.041
regulation of endothelial cell migration GO:0010594 22 0.040
regulation of branching involved in salivary gland morphogenesis by extracellular matrix epithelial cell signaling GO:0060668 1 0.040
cellular component assembly involved in morphogenesis GO:0010927 139 0.040
reactive oxygen species metabolic process GO:0072593 84 0.039
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.039
tube formation GO:0035148 140 0.039
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.039
cholesterol homeostasis GO:0042632 44 0.039
granulocyte chemotaxis GO:0071621 39 0.038
ribose phosphate metabolic process GO:0019693 291 0.038
Mouse
neuronal action potential GO:0019228 54 0.038
negative regulation of phosphate metabolic process GO:0045936 184 0.038
regulation of lipid biosynthetic process GO:0046890 54 0.037
regulation of endothelial cell apoptotic process GO:2000351 9 0.037
organic hydroxy compound metabolic process GO:1901615 203 0.037
response to peptide hormone GO:0043434 127 0.037
cartilage development GO:0051216 140 0.037
myeloid cell homeostasis GO:0002262 114 0.037
wnt signaling pathway GO:0016055 188 0.037
peptidyl proline hydroxylation GO:0019511 3 0.037
positive regulation of transferase activity GO:0051347 167 0.037
cofactor metabolic process GO:0051186 80 0.036
multicellular organismal metabolic process GO:0044236 28 0.036
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.036
termination of rna polymerase i transcription GO:0006363 2 0.036
multicellular organismal signaling GO:0035637 91 0.035
skeletal system morphogenesis GO:0048705 203 0.035
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.035
response to decreased oxygen levels GO:0036293 59 0.035
membrane lipid metabolic process GO:0006643 53 0.035
negative regulation of phosphorylation GO:0042326 166 0.035
wound healing GO:0042060 157 0.035
Rat
erk1 and erk2 cascade GO:0070371 77 0.035
regulation of blood pressure GO:0008217 93 0.034
protein localization to organelle GO:0033365 185 0.034
regulation of protein transport GO:0051223 163 0.034
regulation of receptor activity GO:0010469 41 0.034
positive regulation of angiogenesis GO:0045766 46 0.034
activation of mapk activity GO:0000187 59 0.033
glomerular visceral epithelial cell differentiation GO:0072112 10 0.033
muscle cell differentiation GO:0042692 261 0.033
transcription initiation from rna polymerase i promoter GO:0006361 4 0.033
intracellular protein transport GO:0006886 204 0.033
nuclear import GO:0051170 95 0.033
acetylcholine transport GO:0015870 2 0.033
ossification GO:0001503 216 0.032
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.032
granulocyte migration GO:0097530 43 0.032
response to estrogen GO:0043627 24 0.032
Rat
blood vessel endothelial cell migration GO:0043534 23 0.032
glucose homeostasis GO:0042593 128 0.032
multicellular organismal macromolecule metabolic process GO:0044259 19 0.032
myelination GO:0042552 74 0.032
macrophage chemotaxis GO:0048246 14 0.032
stem cell maintenance GO:0019827 130 0.032
non canonical wnt signaling pathway GO:0035567 33 0.032
nucleocytoplasmic transport GO:0006913 139 0.031
positive regulation of hydrolase activity GO:0051345 148 0.031
regulation of protein stability GO:0031647 52 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.031
peptide transport GO:0015833 133 0.031
regulation of cell growth GO:0001558 91 0.031
cognition GO:0050890 149 0.031
post embryonic camera type eye development GO:0031077 8 0.031
lipid transport GO:0006869 98 0.031
organelle fission GO:0048285 170 0.031
membrane lipid biosynthetic process GO:0046467 32 0.031
response to hydrogen peroxide GO:0042542 32 0.031
lung cell differentiation GO:0060479 30 0.030
neuron migration GO:0001764 122 0.030
plasma lipoprotein particle clearance GO:0034381 13 0.030
cardiac muscle hypertrophy GO:0003300 23 0.030
modification dependent protein catabolic process GO:0019941 133 0.030
regulation of response to wounding GO:1903034 189 0.030
regulation of chemotaxis GO:0050920 53 0.030
gliogenesis GO:0042063 141 0.030
nephron epithelium development GO:0072009 92 0.030
positive regulation of phospholipase activity GO:0010518 3 0.030
ion transmembrane transport GO:0034220 361 0.030
leukocyte proliferation GO:0070661 172 0.030
cardiac chamber development GO:0003205 108 0.030
epithelial tube formation GO:0072175 130 0.030
steroid metabolic process GO:0008202 119 0.029
morphogenesis of a polarized epithelium GO:0001738 37 0.029
regulation of reactive oxygen species metabolic process GO:2000377 40 0.029
regulation of blood circulation GO:1903522 93 0.029
production of molecular mediator of immune response GO:0002440 103 0.029
gastrulation GO:0007369 116 0.029
axon ensheathment GO:0008366 76 0.029
telencephalon development GO:0021537 186 0.029
development of primary female sexual characteristics GO:0046545 73 0.029
microtubule based process GO:0007017 236 0.029
molting cycle GO:0042303 90 0.029
tissue migration GO:0090130 68 0.029
negative regulation of angiogenesis GO:0016525 25 0.029
establishment of protein localization to organelle GO:0072594 118 0.029
post embryonic organ development GO:0048569 17 0.028
Fly
protein import GO:0017038 101 0.028
regulation of vasculature development GO:1901342 88 0.028
cellular response to oxygen radical GO:0071450 14 0.028
response to lipopolysaccharide GO:0032496 128 0.028
astrocyte differentiation GO:0048708 43 0.028
regulation of protein binding GO:0043393 60 0.028
cell growth GO:0016049 130 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.028
cytokine production GO:0001816 319 0.028
muscle hypertrophy GO:0014896 24 0.027
regulation of neuron differentiation GO:0045664 281 0.027
Mouse
hair follicle development GO:0001942 85 0.027
response to acid chemical GO:0001101 111 0.027
Rat
cell cell junction organization GO:0045216 72 0.027
heart process GO:0003015 94 0.027
muscle contraction GO:0006936 101 0.027
amide transport GO:0042886 138 0.027
regulation of proteolysis GO:0030162 164 0.027
Human Mouse Rat Fly
phospholipid transport GO:0015914 21 0.027
establishment or maintenance of cell polarity GO:0007163 86 0.027
regionalization GO:0003002 337 0.027
protein import into nucleus GO:0006606 95 0.027
positive regulation of map kinase activity GO:0043406 84 0.027
negative regulation of proteolysis GO:0045861 74 0.027
Human Mouse Rat Fly
branching morphogenesis of an epithelial tube GO:0048754 159 0.027
cation transport GO:0006812 399 0.027
cellular response to organonitrogen compound GO:0071417 145 0.027
endothelial cell proliferation GO:0001935 27 0.027
monosaccharide transport GO:0015749 58 0.027
regulation of angiogenesis GO:0045765 81 0.026
neuron apoptotic process GO:0051402 142 0.026
cardiac chamber morphogenesis GO:0003206 93 0.026
regulation of cell substrate adhesion GO:0010810 73 0.026
apical constriction GO:0003383 4 0.026
female gonad development GO:0008585 71 0.026
negative regulation of ossification GO:0030279 49 0.026
actin cytoskeleton organization GO:0030036 220 0.026
positive regulation of cell activation GO:0050867 158 0.026
positive regulation of creb transcription factor activity GO:0032793 4 0.026
skeletal muscle cell differentiation GO:0035914 66 0.026
regulation of cellular response to oxidative stress GO:1900407 19 0.026
cellular protein catabolic process GO:0044257 155 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
skin morphogenesis GO:0043589 38 0.026
purine containing compound metabolic process GO:0072521 311 0.026
Mouse
negative regulation of chemotaxis GO:0050922 11 0.026
peptide secretion GO:0002790 114 0.026
embryonic limb morphogenesis GO:0030326 126 0.026
substrate adhesion dependent cell spreading GO:0034446 30 0.026
ear morphogenesis GO:0042471 118 0.025
nitrogen compound transport GO:0071705 271 0.025
generation of precursor metabolites and energy GO:0006091 103 0.025
kidney epithelium development GO:0072073 121 0.025
lipoprotein metabolic process GO:0042157 43 0.025
negative regulation of lymphocyte activation GO:0051250 91 0.025
negative regulation of protein processing GO:0010955 79 0.025
Human Mouse Rat Fly
nucleoside phosphate metabolic process GO:0006753 338 0.025
Mouse
regulation of blood vessel size GO:0050880 56 0.025
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.025
positive regulation of chemotaxis GO:0050921 38 0.025
actin filament organization GO:0007015 113 0.025
regulation of inflammatory response GO:0050727 147 0.025
potassium ion transport GO:0006813 52 0.025
cellular response to acid chemical GO:0071229 68 0.025
antibacterial peptide biosynthetic process GO:0002780 2 0.025
protein processing GO:0016485 163 0.025
Human Mouse Rat Fly
dna templated transcription termination GO:0006353 4 0.024
response to interleukin 1 GO:0070555 11 0.024
protein targeting GO:0006605 143 0.024
regulation of epithelial cell proliferation GO:0050678 141 0.024
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.024
organophosphate catabolic process GO:0046434 232 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
Human
lamellipodium organization GO:0097581 29 0.024
retinal blood vessel morphogenesis GO:0061304 3 0.024
response to alkaloid GO:0043279 34 0.024
regulation of protein tyrosine kinase activity GO:0061097 17 0.024
regulation of membrane potential GO:0042391 192 0.024
cellular response to amino acid stimulus GO:0071230 29 0.024
negative regulation of apoptotic signaling pathway GO:2001234 104 0.024
keratinocyte differentiation GO:0030216 48 0.024
intrinsic apoptotic signaling pathway GO:0097193 132 0.024
nephron development GO:0072006 109 0.024
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
response to alcohol GO:0097305 48 0.023
cell junction organization GO:0034330 77 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
trabecula formation GO:0060343 24 0.023
homeostasis of number of cells GO:0048872 210 0.023
extrinsic apoptotic signaling pathway GO:0097191 126 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.023
chondroblast differentiation GO:0060591 2 0.023
body morphogenesis GO:0010171 45 0.023
renal filtration cell differentiation GO:0061318 10 0.023
mitotic cell cycle GO:0000278 195 0.023
lung epithelial cell differentiation GO:0060487 29 0.022
mitotic cell cycle process GO:1903047 159 0.022
vasoconstriction GO:0042310 27 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
b cell activation GO:0042113 161 0.022
response to nicotine GO:0035094 6 0.022
innate immune response GO:0045087 157 0.022
fatty acid transmembrane transport GO:1902001 1 0.022
negative regulation of protein kinase b signaling GO:0051898 18 0.022
negative regulation of smooth muscle cell migration GO:0014912 2 0.022
bmp signaling pathway GO:0030509 93 0.022
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.022
carbohydrate transport GO:0008643 62 0.022
interspecies interaction between organisms GO:0044419 83 0.022
cerebral cortex development GO:0021987 86 0.022
negative regulation of cell cycle GO:0045786 123 0.021
muscle adaptation GO:0043500 39 0.021
positive regulation of striated muscle contraction GO:0045989 3 0.021
carbohydrate metabolic process GO:0005975 230 0.021
g0 to g1 transition GO:0045023 3 0.021
regulation of response to oxidative stress GO:1902882 19 0.021
regulation of cell adhesion GO:0030155 154 0.021
Fly
positive regulation of fat cell differentiation GO:0045600 32 0.021
cellular response to dna damage stimulus GO:0006974 207 0.021
mitotic cytokinesis GO:0000281 4 0.021
establishment of planar polarity GO:0001736 28 0.021
potassium ion transmembrane transport GO:0071805 43 0.021
positive regulation of endothelial cell migration GO:0010595 12 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
action potential GO:0001508 78 0.021
transcription from rna polymerase i promoter GO:0006360 13 0.021
nucleotide metabolic process GO:0009117 332 0.021
Mouse
regulation of anatomical structure size GO:0090066 178 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
epithelial cell proliferation GO:0050673 174 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.020
regulation of neuron death GO:1901214 134 0.020
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.020
endoderm development GO:0007492 45 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
inter male aggressive behavior GO:0002121 3 0.020

Timp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.086
disease of anatomical entity DOID:7 0 0.086
immune system disease DOID:2914 0 0.059
central nervous system disease DOID:331 0 0.044
sensory system disease DOID:0050155 0 0.044
eye and adnexa disease DOID:1492 0 0.041
eye disease DOID:5614 0 0.041
retinal disease DOID:5679 0 0.034
retinal degeneration DOID:8466 0 0.034
cardiovascular system disease DOID:1287 0 0.031
neuromuscular disease DOID:440 0 0.030
neuropathy DOID:870 0 0.030
lipid metabolism disorder DOID:3146 0 0.029
disease of metabolism DOID:0014667 0 0.029
inherited metabolic disorder DOID:655 0 0.029
hematopoietic system disease DOID:74 0 0.028
charcot marie tooth disease DOID:10595 0 0.022
neurodegenerative disease DOID:1289 0 0.021
heart disease DOID:114 0 0.020