Rattus norvegicus

48 known processes

Pggt1b

protein geranylgeranyltransferase type I, beta subunit

Pggt1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein complex assembly GO:0006461 263 0.256
cellular component biogenesis GO:0044085 368 0.238
protein localization GO:0008104 191 0.206
macromolecule localization GO:0033036 252 0.162
protein complex subunit organization GO:0071822 302 0.144
cellular component assembly GO:0022607 360 0.128
vesicle mediated transport GO:0016192 181 0.127
cellular catabolic process GO:0044248 295 0.116
single organism cellular localization GO:1902580 102 0.114
regulation of cellular localization GO:0060341 263 0.113
macromolecular complex assembly GO:0065003 273 0.109
catabolic process GO:0009056 351 0.107
intracellular signal transduction GO:0035556 314 0.105
Fly
synaptic growth at neuromuscular junction GO:0051124 1 0.102
organic substance catabolic process GO:1901575 316 0.101
carbohydrate derivative metabolic process GO:1901135 346 0.100
regulation of multicellular organismal development GO:2000026 376 0.091
response to acid chemical GO:0001101 222 0.090
protein complex biogenesis GO:0070271 263 0.081
developmental process involved in reproduction GO:0003006 159 0.077
regulation of cellular component organization GO:0051128 368 0.076
rna metabolic process GO:0016070 406 0.076
single organism membrane organization GO:0044802 74 0.073
response to electrical stimulus involved in regulation of muscle adaptation GO:0014878 4 0.068
organelle organization GO:0006996 266 0.068
positive regulation of cell proliferation GO:0008284 249 0.066
protein localization to membrane GO:0072657 36 0.066
intracellular transport GO:0046907 185 0.064
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.064
cellular component movement GO:0006928 248 0.064
nucleic acid templated transcription GO:0097659 379 0.062
regulation of transcription dna templated GO:0006355 374 0.060
single organism reproductive process GO:0044702 297 0.060
protein oligomerization GO:0051259 191 0.059
membrane organization GO:0061024 94 0.059
protein homooligomerization GO:0051260 91 0.058
regulation of rna metabolic process GO:0051252 391 0.058
organic acid metabolic process GO:0006082 292 0.057
neurological system process GO:0050877 219 0.057
single organism intracellular transport GO:1902582 166 0.056
macromolecular complex subunit organization GO:0043933 339 0.055
regulation of anatomical structure size GO:0090066 135 0.054
organophosphate metabolic process GO:0019637 370 0.054
transcription dna templated GO:0006351 377 0.054
secretion GO:0046903 307 0.053
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.053
positive regulation of biosynthetic process GO:0009891 319 0.053
establishment of protein localization GO:0045184 141 0.053
cellular protein localization GO:0034613 122 0.051
regulation of rna biosynthetic process GO:2001141 381 0.051
cell cycle GO:0007049 101 0.050
positive regulation of transport GO:0051050 245 0.049
multi organism reproductive process GO:0044703 262 0.049
synaptic transmission GO:0007268 235 0.048
multicellular organismal reproductive process GO:0048609 233 0.048
regulation of protein metabolic process GO:0051246 289 0.047
locomotion GO:0040011 237 0.047
positive regulation of cellular component organization GO:0051130 200 0.047
regulation of secretion GO:0051046 224 0.046
action potential GO:0001508 54 0.046
regulation of catabolic process GO:0009894 113 0.045
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.043
regulation of cellular protein metabolic process GO:0032268 267 0.043
response to oxygen levels GO:0070482 265 0.043
response to decreased oxygen levels GO:0036293 237 0.042
secretion by cell GO:0032940 248 0.042
positive regulation of developmental process GO:0051094 283 0.041
nucleoside phosphate metabolic process GO:0006753 283 0.041
programmed cell death GO:0012501 392 0.040
response to insulin GO:0032868 133 0.040
transcription from rna polymerase ii promoter GO:0006366 252 0.040
glycosyl compound metabolic process GO:1901657 182 0.039
response to nutrient levels GO:0031667 370 0.039
response to metal ion GO:0010038 253 0.036
cellular macromolecule localization GO:0070727 122 0.036
intracellular protein transport GO:0006886 79 0.035
multicellular organism reproduction GO:0032504 233 0.035
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.035
response to inorganic substance GO:0010035 377 0.035
homeostatic process GO:0042592 331 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
cell cell signaling GO:0007267 335 0.033
rna biosynthetic process GO:0032774 380 0.033
purine containing compound metabolic process GO:0072521 253 0.033
purine nucleotide metabolic process GO:0006163 229 0.033
positive regulation of phosphorus metabolic process GO:0010562 262 0.033
Fly
reproduction GO:0000003 245 0.032
response to starvation GO:0042594 59 0.032
muscle system process GO:0003012 115 0.032
aromatic compound catabolic process GO:0019439 168 0.032
nucleotide metabolic process GO:0009117 279 0.032
regulation of membrane potential GO:0042391 110 0.032
single organism organelle organization GO:1902589 180 0.032
organelle localization GO:0051640 55 0.032
cation transport GO:0006812 382 0.032
response to extracellular stimulus GO:0009991 380 0.032
nucleoside catabolic process GO:0009164 126 0.032
behavior GO:0007610 205 0.031
multicellular organismal signaling GO:0035637 44 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
cellular chemical homeostasis GO:0055082 247 0.031
cell projection organization GO:0030030 302 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
regulation of molecular function GO:0065009 398 0.030
regulation of apoptotic process GO:0042981 335 0.030
protein transport GO:0015031 132 0.030
endocytosis GO:0006897 84 0.030
purine nucleoside catabolic process GO:0006152 124 0.030
amine metabolic process GO:0009308 38 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.029
Fly
ribose phosphate metabolic process GO:0019693 235 0.029
regulation of cell development GO:0060284 263 0.029
muscle contraction GO:0006936 88 0.029
response to hypoxia GO:0001666 231 0.029
cell morphogenesis involved in differentiation GO:0000904 119 0.028
regulation of nervous system development GO:0051960 264 0.028
negative regulation of cell death GO:0060548 229 0.028
transmission of nerve impulse GO:0019226 42 0.027
negative regulation of apoptotic process GO:0043066 181 0.027
response to biotic stimulus GO:0009607 226 0.027
positive regulation of molecular function GO:0044093 230 0.027
regulation of secretion by cell GO:1903530 208 0.027
regulation of cellular component size GO:0032535 51 0.027
positive regulation of gene expression GO:0010628 244 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
growth GO:0040007 165 0.026
positive regulation of cellular protein metabolic process GO:0032270 167 0.026
regulation of vesicle mediated transport GO:0060627 81 0.026
cellular response to stress GO:0033554 269 0.026
cytoplasmic transport GO:0016482 115 0.026
establishment of organelle localization GO:0051656 37 0.026
gamete generation GO:0007276 124 0.026
purine ribonucleotide catabolic process GO:0009154 136 0.025
response to external biotic stimulus GO:0043207 221 0.025
axis specification GO:0009798 4 0.025
reproductive process GO:0022414 372 0.025
purine nucleoside metabolic process GO:0042278 169 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
organonitrogen compound catabolic process GO:1901565 179 0.025
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
aging GO:0007568 241 0.024
positive regulation of secretion by cell GO:1903532 128 0.024
endomembrane system organization GO:0010256 48 0.024
single organism catabolic process GO:0044712 283 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
regulation of system process GO:0044057 208 0.024
regulation of programmed cell death GO:0043067 341 0.024
nucleoside triphosphate catabolic process GO:0009143 123 0.024
positive regulation of ion transport GO:0043270 94 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
response to other organism GO:0051707 220 0.024
response to glucocorticoid GO:0051384 223 0.023
single organism biosynthetic process GO:0044711 342 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
sexual reproduction GO:0019953 148 0.023
neuron projection development GO:0031175 273 0.023
spindle organization GO:0007051 2 0.023
signal release GO:0023061 145 0.022
regulation of cellular component biogenesis GO:0044087 86 0.022
establishment of protein localization to membrane GO:0090150 16 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
Fly
purine nucleotide catabolic process GO:0006195 136 0.022
chemical homeostasis GO:0048878 292 0.022
cellular ion homeostasis GO:0006873 184 0.022
ribonucleotide catabolic process GO:0009261 136 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
nucleoside metabolic process GO:0009116 179 0.022
oxoacid metabolic process GO:0043436 290 0.022
anterior posterior pattern specification GO:0009952 1 0.021
response to peptide GO:1901652 292 0.021
negative regulation of metabolic process GO:0009892 331 0.021
apoptotic process GO:0006915 381 0.021
response to toxic substance GO:0009636 133 0.021
cellular response to external stimulus GO:0071496 118 0.021
positive regulation of nervous system development GO:0051962 178 0.020
transmembrane transport GO:0055085 412 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
glucosamine metabolic process GO:0006041 3 0.020
protein phosphorylation GO:0006468 345 0.020
asymmetric protein localization GO:0008105 2 0.020
guanosine containing compound metabolic process GO:1901068 74 0.020
mitochondrion localization GO:0051646 6 0.020
cell part morphogenesis GO:0032990 123 0.020
nitrogen compound transport GO:0071705 229 0.020
response to radiation GO:0009314 137 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
regulation of catalytic activity GO:0050790 304 0.019
central nervous system development GO:0007417 311 0.019
regulation of protein localization GO:0032880 81 0.019
organophosphate catabolic process GO:0046434 148 0.019
chromosome segregation GO:0007059 2 0.019
regulation of cellular catabolic process GO:0031329 101 0.019
localization of cell GO:0051674 202 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
response to carbohydrate GO:0009743 183 0.019
protein heterooligomerization GO:0051291 89 0.019
cellular response to hormone stimulus GO:0032870 247 0.019
nucleotide catabolic process GO:0009166 139 0.019
regulation of phosphorylation GO:0042325 248 0.019
Fly
response to lipopolysaccharide GO:0032496 191 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
regulation of cell migration GO:0030334 128 0.018
nucleoside triphosphate metabolic process GO:0009141 144 0.018
centrosome organization GO:0051297 1 0.018
eye morphogenesis GO:0048592 4 0.018
cellular amine metabolic process GO:0044106 38 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
positive regulation of cell development GO:0010720 176 0.018
receptor localization to synapse GO:0097120 2 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
regulation of neurogenesis GO:0050767 247 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.018
regulation of cellular component movement GO:0051270 150 0.018
response to corticosteroid GO:0031960 235 0.018
regulation of establishment of protein localization GO:0070201 69 0.018
neuron differentiation GO:0030182 368 0.017
cell morphogenesis GO:0000902 142 0.017
response to nutrient GO:0007584 248 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
negative regulation of gene expression GO:0010629 199 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
response to bacterium GO:0009617 200 0.017
regulation of growth GO:0040008 105 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
Fly
neuronal action potential GO:0019228 35 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
regulation of cell proliferation GO:0042127 359 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
Fly
potassium ion transport GO:0006813 97 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.016
response to peptide hormone GO:0043434 278 0.016
response to growth factor GO:0070848 189 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
dendrite morphogenesis GO:0048813 43 0.016
cell migration GO:0016477 197 0.016
cellular component morphogenesis GO:0032989 155 0.016
positive regulation of secretion GO:0051047 140 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
cellular amino acid biosynthetic process GO:0008652 32 0.016
response to cytokine GO:0034097 215 0.016
axon cargo transport GO:0008088 1 0.016
muscle structure development GO:0061061 87 0.016
ras protein signal transduction GO:0007265 29 0.015
Fly
smooth muscle cell proliferation GO:0048659 77 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
Fly
monovalent inorganic cation transport GO:0015672 172 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
regulation of cell cycle GO:0051726 73 0.015
heterocycle catabolic process GO:0046700 167 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
cell cycle process GO:0022402 57 0.015
regulation of signal transduction GO:0009966 318 0.015
Fly
cell activation GO:0001775 97 0.015
microtubule organizing center organization GO:0031023 1 0.014
cellular protein complex assembly GO:0043623 44 0.014
neuron development GO:0048666 286 0.014
protein targeting GO:0006605 61 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
organ morphogenesis GO:0009887 75 0.014
cellular macromolecular complex assembly GO:0034622 58 0.014
negative regulation of developmental process GO:0051093 125 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
negative regulation of cell communication GO:0010648 158 0.014
cell motility GO:0048870 202 0.014
regulation of phosphate metabolic process GO:0019220 349 0.014
Fly
response to amino acid GO:0043200 75 0.014
rna localization GO:0006403 4 0.014
regulation of synaptic transmission GO:0050804 141 0.014
ion homeostasis GO:0050801 212 0.014
regulation of cell differentiation GO:0045595 320 0.014
centrosome cycle GO:0007098 1 0.013
head development GO:0060322 247 0.013
cellular cation homeostasis GO:0030003 180 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
muscle cell differentiation GO:0042692 52 0.013
response to purine containing compound GO:0014074 126 0.013
regulation of small gtpase mediated signal transduction GO:0051056 48 0.013
Fly
neuron projection morphogenesis GO:0048812 122 0.013
chemotaxis GO:0006935 66 0.013
tissue development GO:0009888 252 0.013
Fly
ensheathment of neurons GO:0007272 40 0.013
cellular ketone metabolic process GO:0042180 51 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
positive regulation of release of cytochrome c from mitochondria GO:0090200 3 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
Fly
positive regulation of protein modification process GO:0031401 142 0.013
positive regulation of signaling GO:0023056 270 0.013
Fly
hormone secretion GO:0046879 115 0.013
leukocyte activation GO:0045321 76 0.012
macroautophagy GO:0016236 4 0.012
response to monosaccharide GO:0034284 159 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
protein tetramerization GO:0051262 38 0.012
metal ion transport GO:0030001 289 0.012
forebrain development GO:0030900 98 0.012
kidney development GO:0001822 67 0.012
multicellular organism growth GO:0035264 1 0.012
regulation of cell motility GO:2000145 131 0.012
purine containing compound catabolic process GO:0072523 138 0.012
regulation of hormone levels GO:0010817 187 0.012
cytoskeleton organization GO:0007010 111 0.012
regulation of locomotion GO:0040012 148 0.012
response to ketone GO:1901654 182 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
lipid metabolic process GO:0006629 283 0.012
response to ethanol GO:0045471 162 0.012
defense response GO:0006952 194 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
response to glucose GO:0009749 136 0.012
establishment of synaptic vesicle localization GO:0097480 23 0.012
gland development GO:0048732 155 0.012
regulation of protein transport GO:0051223 68 0.012
rhythmic process GO:0048511 156 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
response to retinoic acid GO:0032526 63 0.011
brain development GO:0007420 247 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
skeletal muscle tissue development GO:0007519 31 0.011
cellular amino acid catabolic process GO:0009063 21 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
establishment of vesicle localization GO:0051650 31 0.011
neurotransmitter gated ion channel clustering GO:0072578 3 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
regeneration GO:0031099 163 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
feeding behavior GO:0007631 53 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
microtubule cytoskeleton organization GO:0000226 25 0.011
organ regeneration GO:0031100 101 0.011
carbohydrate metabolic process GO:0005975 130 0.011
positive regulation of synaptic transmission GO:0050806 62 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
gtp metabolic process GO:0046039 72 0.011
protein homotetramerization GO:0051289 25 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
synapse organization GO:0050808 46 0.011
metal ion homeostasis GO:0055065 186 0.011
small molecule biosynthetic process GO:0044283 124 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
axonogenesis GO:0007409 71 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
positive regulation of potassium ion transport GO:0043268 13 0.011
cell projection morphogenesis GO:0048858 123 0.011
regulation of ion transport GO:0043269 245 0.011
vesicle fusion with golgi apparatus GO:0048280 4 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
vesicle organization GO:0016050 29 0.010
actin filament based process GO:0030029 86 0.010
regulation of metal ion transport GO:0010959 118 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
cellular response to hypoxia GO:0071456 51 0.010
biological adhesion GO:0022610 110 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
calcium ion homeostasis GO:0055074 162 0.010
cellular response to oxygen levels GO:0071453 60 0.010
negative regulation of transport GO:0051051 136 0.010

Pggt1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012
inherited metabolic disorder DOID:655 0 0.012
disease of metabolism DOID:0014667 0 0.012