Rattus norvegicus

0 known processes

Ripk2

receptor-interacting serine-threonine kinase 2

Ripk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of apoptotic process GO:0042981 335 0.125
negative regulation of programmed cell death GO:0043069 183 0.096
apoptotic process GO:0006915 381 0.091
programmed cell death GO:0012501 392 0.088
Rat
protein phosphorylation GO:0006468 345 0.086
cellular amino acid metabolic process GO:0006520 107 0.084
regulation of programmed cell death GO:0043067 341 0.084
Rat
negative regulation of cell death GO:0060548 229 0.081
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.081
regulation of phosphate metabolic process GO:0019220 349 0.076
intracellular signal transduction GO:0035556 314 0.073
response to cytokine GO:0034097 215 0.072
regulation of rna metabolic process GO:0051252 391 0.068
regulation of phosphorus metabolic process GO:0051174 349 0.068
negative regulation of apoptotic process GO:0043066 181 0.066
regulation of cell differentiation GO:0045595 320 0.064
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.062
positive regulation of cell proliferation GO:0008284 249 0.060
positive regulation of biosynthetic process GO:0009891 319 0.058
rna biosynthetic process GO:0032774 380 0.057
regulation of transcription dna templated GO:0006355 374 0.056
oxoacid metabolic process GO:0043436 290 0.056
regulation of multicellular organismal development GO:2000026 376 0.054
regulation of nucleic acid templated transcription GO:1903506 380 0.054
organic acid metabolic process GO:0006082 292 0.053
regulation of neurogenesis GO:0050767 247 0.052
neuron differentiation GO:0030182 368 0.052
reproductive process GO:0022414 372 0.051
regulation of nervous system development GO:0051960 264 0.050
response to tumor necrosis factor GO:0034612 56 0.050
response to bacterium GO:0009617 200 0.049
single organism biosynthetic process GO:0044711 342 0.049
response to extracellular stimulus GO:0009991 380 0.048
protein complex assembly GO:0006461 263 0.048
Rat
amine metabolic process GO:0009308 38 0.047
positive regulation of cell communication GO:0010647 271 0.046
macromolecular complex assembly GO:0065003 273 0.046
Rat
response to peptide GO:1901652 292 0.046
neuron projection development GO:0031175 273 0.045
regulation of signal transduction GO:0009966 318 0.045
organophosphate metabolic process GO:0019637 370 0.045
cellular response to hormone stimulus GO:0032870 247 0.045
regulation of cellular amino acid metabolic process GO:0006521 2 0.044
cellular response to peptide hormone stimulus GO:0071375 120 0.044
regulation of cellular amine metabolic process GO:0033238 8 0.044
macromolecule localization GO:0033036 252 0.044
response to nutrient GO:0007584 248 0.043
response to nutrient levels GO:0031667 370 0.043
positive regulation of response to stimulus GO:0048584 285 0.042
positive regulation of phosphorus metabolic process GO:0010562 262 0.042
carbohydrate derivative metabolic process GO:1901135 346 0.042
transcription dna templated GO:0006351 377 0.042
positive regulation of nucleic acid templated transcription GO:1903508 197 0.041
single organism reproductive process GO:0044702 297 0.040
cellular ketone metabolic process GO:0042180 51 0.040
response to molecule of bacterial origin GO:0002237 194 0.039
macromolecular complex subunit organization GO:0043933 339 0.039
Rat
response to wounding GO:0009611 254 0.039
cellular response to nitrogen compound GO:1901699 210 0.038
response to lipopolysaccharide GO:0032496 191 0.038
carboxylic acid metabolic process GO:0019752 289 0.038
positive regulation of phosphate metabolic process GO:0045937 262 0.038
transcription from rna polymerase ii promoter GO:0006366 252 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
positive regulation of gene expression GO:0010628 244 0.037
cellular response to oxygen containing compound GO:1901701 386 0.036
cellular component movement GO:0006928 248 0.036
regulation of cell development GO:0060284 263 0.036
multicellular organism reproduction GO:0032504 233 0.036
catabolic process GO:0009056 351 0.036
neuron development GO:0048666 286 0.036
positive regulation of phosphorylation GO:0042327 177 0.035
taxis GO:0042330 67 0.034
cellular amine metabolic process GO:0044106 38 0.034
positive regulation of rna metabolic process GO:0051254 203 0.034
positive regulation of cell differentiation GO:0045597 217 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.034
response to acid chemical GO:0001101 222 0.034
negative regulation of macromolecule metabolic process GO:0010605 260 0.034
response to decreased oxygen levels GO:0036293 237 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
positive regulation of transcription dna templated GO:0045893 197 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
positive regulation of cell death GO:0010942 184 0.032
Rat
nucleic acid templated transcription GO:0097659 379 0.032
ribonucleotide metabolic process GO:0009259 231 0.031
purine containing compound metabolic process GO:0072521 253 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.031
multicellular organismal reproductive process GO:0048609 233 0.031
protein complex biogenesis GO:0070271 263 0.031
Rat
regulation of cellular component organization GO:0051128 368 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.031
behavior GO:0007610 205 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
immune response GO:0006955 104 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
nucleotide metabolic process GO:0009117 279 0.030
cellular response to peptide GO:1901653 133 0.030
negative regulation of metabolic process GO:0009892 331 0.029
regulation of cell proliferation GO:0042127 359 0.029
reproduction GO:0000003 245 0.029
cation transport GO:0006812 382 0.029
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.029
neuron projection morphogenesis GO:0048812 122 0.029
regulation of intracellular signal transduction GO:1902531 218 0.029
cellular catabolic process GO:0044248 295 0.028
aging GO:0007568 241 0.028
regulation of protein metabolic process GO:0051246 289 0.028
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.028
positive regulation of developmental process GO:0051094 283 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
response to estrogen GO:0043627 232 0.028
response to biotic stimulus GO:0009607 226 0.028
rna metabolic process GO:0016070 406 0.027
cellular response to organonitrogen compound GO:0071417 197 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
regulation of molecular function GO:0065009 398 0.027
locomotion GO:0040011 237 0.027
positive regulation of rna biosynthetic process GO:1902680 197 0.026
positive regulation of cell development GO:0010720 176 0.026
cell projection organization GO:0030030 302 0.026
cell motility GO:0048870 202 0.026
cellular component assembly GO:0022607 360 0.026
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
cellular response to tumor necrosis factor GO:0071356 46 0.026
multi organism reproductive process GO:0044703 262 0.026
response to toxic substance GO:0009636 133 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
purine ribonucleotide metabolic process GO:0009150 227 0.025
cell migration GO:0016477 197 0.025
positive regulation of response to external stimulus GO:0032103 51 0.025
cellular response to lipid GO:0071396 201 0.025
tissue development GO:0009888 252 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.025
cell type specific apoptotic process GO:0097285 134 0.025
response to mechanical stimulus GO:0009612 134 0.025
single organism organelle organization GO:1902589 180 0.025
regulation of neuron differentiation GO:0045664 208 0.024
neuron death GO:0070997 127 0.024
response to hypoxia GO:0001666 231 0.024
response to vitamin GO:0033273 131 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
regulation of immune system process GO:0002682 123 0.023
response to transition metal nanoparticle GO:1990267 122 0.023
response to glucocorticoid GO:0051384 223 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
dendrite development GO:0016358 72 0.023
organonitrogen compound biosynthetic process GO:1901566 167 0.023
cellular homeostasis GO:0019725 252 0.023
central nervous system development GO:0007417 311 0.022
protein complex subunit organization GO:0071822 302 0.022
Rat
positive regulation of nervous system development GO:0051962 178 0.022
regulation of cellular localization GO:0060341 263 0.022
sexual reproduction GO:0019953 148 0.022
divalent inorganic cation homeostasis GO:0072507 165 0.022
response to insulin GO:0032868 133 0.022
cellular response to stress GO:0033554 269 0.022
cellular response to cytokine stimulus GO:0071345 127 0.021
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.021
response to metal ion GO:0010038 253 0.021
regulation of phosphorylation GO:0042325 248 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
Rat
regulation of cell migration GO:0030334 128 0.021
response to oxygen levels GO:0070482 265 0.021
maintenance of location GO:0051235 17 0.021
head development GO:0060322 247 0.021
carbohydrate derivative biosynthetic process GO:1901137 124 0.021
cell activation GO:0001775 97 0.021
cellular component biogenesis GO:0044085 368 0.021
Rat
negative regulation of signaling GO:0023057 157 0.021
negative regulation of transport GO:0051051 136 0.021
cytokine mediated signaling pathway GO:0019221 43 0.021
negative regulation of response to stimulus GO:0048585 155 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
transmembrane transport GO:0055085 412 0.020
response to estradiol GO:0032355 164 0.020
response to high density lipoprotein particle GO:0055099 2 0.020
axis specification GO:0009798 4 0.020
organic substance catabolic process GO:1901575 316 0.020
ras protein signal transduction GO:0007265 29 0.020
positive regulation of signal transduction GO:0009967 175 0.020
cellular response to organic cyclic compound GO:0071407 202 0.020
negative regulation of cell communication GO:0010648 158 0.020
protein oligomerization GO:0051259 191 0.019
Rat
anterior posterior pattern specification GO:0009952 1 0.019
mapk cascade GO:0000165 140 0.019
positive regulation of signaling GO:0023056 270 0.019
secretion GO:0046903 307 0.019
negative regulation of gene expression GO:0010629 199 0.019
negative regulation of rna metabolic process GO:0051253 123 0.019
leukocyte activation GO:0045321 76 0.019
regulation of catalytic activity GO:0050790 304 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
response to corticosteroid GO:0031960 235 0.019
metal ion transport GO:0030001 289 0.018
regulation of nucleotide metabolic process GO:0006140 117 0.018
protein localization GO:0008104 191 0.018
positive regulation of secretion GO:0051047 140 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
response to amino acid GO:0043200 75 0.018
response to inorganic substance GO:0010035 377 0.018
negative regulation of signal transduction GO:0009968 83 0.018
response to other organism GO:0051707 220 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
response to oxidative stress GO:0006979 186 0.018
inflammatory response GO:0006954 150 0.018
organ regeneration GO:0031100 101 0.018
proteolysis GO:0006508 175 0.018
response to growth factor GO:0070848 189 0.018
response to peptide hormone GO:0043434 278 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
cell morphogenesis GO:0000902 142 0.017
regulation of cellular component movement GO:0051270 150 0.017
regulation of neuron death GO:1901214 115 0.017
cellular component morphogenesis GO:0032989 155 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
establishment of protein localization GO:0045184 141 0.017
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
localization of cell GO:0051674 202 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
protein autophosphorylation GO:0046777 66 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
lipid storage GO:0019915 1 0.016
nucleoside triphosphate metabolic process GO:0009141 144 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
negative regulation of molecular function GO:0044092 133 0.016
cell cell signaling GO:0007267 335 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
lipid metabolic process GO:0006629 283 0.016
nitrogen compound transport GO:0071705 229 0.016
positive regulation of cell migration GO:0030335 96 0.016
brain development GO:0007420 247 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
signal transduction by phosphorylation GO:0023014 144 0.015
peptidyl amino acid modification GO:0018193 126 0.015
embryonic pattern specification GO:0009880 1 0.015
regulation of ion transport GO:0043269 245 0.015
positive regulation of molecular function GO:0044093 230 0.015
regulation of leukocyte activation GO:0002694 45 0.015
gliogenesis GO:0042063 93 0.015
regulation of mapk cascade GO:0043408 116 0.015
insulin receptor signaling pathway GO:0008286 24 0.015
negative regulation of neuron death GO:1901215 69 0.015
ion transmembrane transport GO:0034220 365 0.015
metal ion homeostasis GO:0055065 186 0.015
gland development GO:0048732 155 0.015
regeneration GO:0031099 163 0.015
glycerolipid metabolic process GO:0046486 67 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
response to radiation GO:0009314 137 0.015
cell projection morphogenesis GO:0048858 123 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
anion transport GO:0006820 178 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
regulation of system process GO:0044057 208 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
regulation of locomotion GO:0040012 148 0.014
lipid biosynthetic process GO:0008610 128 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
organelle organization GO:0006996 266 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
negative regulation of developmental process GO:0051093 125 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
leukocyte differentiation GO:0002521 30 0.014
positive regulation of protein modification process GO:0031401 142 0.014
protein heterooligomerization GO:0051291 89 0.014
Rat
ion homeostasis GO:0050801 212 0.014
chemical homeostasis GO:0048878 292 0.014
positive regulation of immune system process GO:0002684 90 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
defense response GO:0006952 194 0.013
regulation of homeostatic process GO:0032844 101 0.013
gonad development GO:0008406 104 0.013
gamete generation GO:0007276 124 0.013
spermatogenesis GO:0007283 99 0.013
positive regulation of cell motility GO:2000147 97 0.013
immune system process GO:0002376 204 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
response to ethanol GO:0045471 162 0.013
jak stat cascade GO:0007259 26 0.013
neuron apoptotic process GO:0051402 88 0.013
developmental process involved in reproduction GO:0003006 159 0.013
regulation of response to external stimulus GO:0032101 106 0.013
regulation of catabolic process GO:0009894 113 0.013
regulation of neuron projection development GO:0010975 161 0.013
single organism catabolic process GO:0044712 283 0.013
cellular response to biotic stimulus GO:0071216 59 0.013
cellular cation homeostasis GO:0030003 180 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
regulation of secretion by cell GO:1903530 208 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
cytoplasmic transport GO:0016482 115 0.013
regulation of cell motility GO:2000145 131 0.013
cell cycle GO:0007049 101 0.013
cellular protein localization GO:0034613 122 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
single organism behavior GO:0044708 130 0.012
cellular macromolecule localization GO:0070727 122 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
response to ketone GO:1901654 182 0.012
cellular chemical homeostasis GO:0055082 247 0.012
regulation of protein localization GO:0032880 81 0.012
b cell differentiation GO:0030183 2 0.012
reproductive structure development GO:0048608 128 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
regulation of response to stress GO:0080134 126 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
nuclear transport GO:0051169 49 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
eye morphogenesis GO:0048592 4 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
apoptotic signaling pathway GO:0097190 27 0.012
response to antibiotic GO:0046677 39 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
oxidation reduction process GO:0055114 304 0.012
cellular protein complex assembly GO:0043623 44 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
single organism cellular localization GO:1902580 102 0.012
cell growth GO:0016049 104 0.012
heterocycle catabolic process GO:0046700 167 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
growth GO:0040007 165 0.012
regulation of anatomical structure size GO:0090066 135 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
secretion by cell GO:0032940 248 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
multi multicellular organism process GO:0044706 138 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
response to carbohydrate GO:0009743 183 0.011
positive regulation of locomotion GO:0040017 102 0.011
positive regulation of kinase activity GO:0033674 77 0.011
female pregnancy GO:0007565 122 0.011
cell part morphogenesis GO:0032990 123 0.011
regulation of protein transport GO:0051223 68 0.011
muscle cell proliferation GO:0033002 84 0.011
reproductive system development GO:0061458 128 0.011
membrane organization GO:0061024 94 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
cytoskeleton organization GO:0007010 111 0.011
embryonic axis specification GO:0000578 1 0.011
regulation of membrane potential GO:0042391 110 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
purine nucleoside monophosphate metabolic process GO:0009126 84 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
response to interferon gamma GO:0034341 20 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
cellular response to external stimulus GO:0071496 118 0.011
forebrain development GO:0030900 98 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
cellular response to oxidative stress GO:0034599 76 0.011
cellular response to molecule of bacterial origin GO:0071219 56 0.011
positive regulation of catabolic process GO:0009896 78 0.011
homeostatic process GO:0042592 331 0.011
development of primary sexual characteristics GO:0045137 107 0.011
cation homeostasis GO:0055080 195 0.011
cellular response to alcohol GO:0097306 87 0.011
cellular response to interleukin 6 GO:0071354 9 0.011
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.011
synaptic transmission GO:0007268 235 0.011
cellular response to acid chemical GO:0071229 75 0.011
sex differentiation GO:0007548 113 0.010
protein transport GO:0015031 132 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
peptidyl tyrosine phosphorylation GO:0018108 72 0.010
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.010
cellular response to lipopolysaccharide GO:0071222 55 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
male gamete generation GO:0048232 99 0.010
myeloid leukocyte differentiation GO:0002573 20 0.010
amino acid transport GO:0006865 70 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
carboxylic acid transport GO:0046942 115 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
circulatory system process GO:0003013 183 0.010
erk1 and erk2 cascade GO:0070371 48 0.010
organic acid transport GO:0015849 116 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
regulation of t cell migration GO:2000404 1 0.010
regulation of protein modification process GO:0031399 194 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
aromatic compound catabolic process GO:0019439 168 0.010
erythrocyte differentiation GO:0030218 1 0.010
circadian rhythm GO:0007623 88 0.010

Ripk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
organ system cancer DOID:0050686 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
cancer DOID:162 0 0.010