Rattus norvegicus

17 known processes

Asah1

N-acylsphingosine amidohydrolase (acid ceramidase) 1

(Aliases: Asah)

Asah1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carbohydrate derivative metabolic process GO:1901135 346 0.109
vesicle mediated transport GO:0016192 181 0.102
positive regulation of cellular component movement GO:0051272 102 0.093
organic substance catabolic process GO:1901575 316 0.091
catabolic process GO:0009056 351 0.083
positive regulation of cell proliferation GO:0008284 249 0.076
regulation of protein metabolic process GO:0051246 289 0.070
protein phosphorylation GO:0006468 345 0.061
macromolecule localization GO:0033036 252 0.061
purine nucleotide metabolic process GO:0006163 229 0.060
cell migration GO:0016477 197 0.055
multi organism reproductive process GO:0044703 262 0.054
reproductive process GO:0022414 372 0.052
positive regulation of transport GO:0051050 245 0.051
regulation of cell proliferation GO:0042127 359 0.050
single organism intracellular transport GO:1902582 166 0.048
protein transport GO:0015031 132 0.047
cell activation GO:0001775 97 0.046
locomotion GO:0040011 237 0.045
single organism reproductive process GO:0044702 297 0.045
cellular component movement GO:0006928 248 0.045
negative regulation of programmed cell death GO:0043069 183 0.044
cellular catabolic process GO:0044248 295 0.044
cell adhesion GO:0007155 110 0.041
purine containing compound metabolic process GO:0072521 253 0.041
secretion GO:0046903 307 0.041
divalent metal ion transport GO:0070838 132 0.041
intracellular transport GO:0046907 185 0.040
carbohydrate derivative catabolic process GO:1901136 147 0.039
aging GO:0007568 241 0.039
regulation of ion transport GO:0043269 245 0.039
localization of cell GO:0051674 202 0.039
organic anion transport GO:0015711 132 0.038
establishment of protein localization GO:0045184 141 0.038
regulation of cell migration GO:0030334 128 0.037
ribonucleotide metabolic process GO:0009259 231 0.037
intracellular protein transport GO:0006886 79 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
metal ion transport GO:0030001 289 0.035
protein localization GO:0008104 191 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
organonitrogen compound catabolic process GO:1901565 179 0.035
cellular macromolecule localization GO:0070727 122 0.034
cellular calcium ion homeostasis GO:0006874 160 0.034
biological adhesion GO:0022610 110 0.034
positive regulation of molecular function GO:0044093 230 0.034
regulation of cellular ketone metabolic process GO:0010565 27 0.033
positive regulation of cellular component organization GO:0051130 200 0.033
regulation of response to external stimulus GO:0032101 106 0.033
regulation of locomotion GO:0040012 148 0.033
regulation of cell motility GO:2000145 131 0.033
regulation of vesicle mediated transport GO:0060627 81 0.032
transmembrane transport GO:0055085 412 0.032
reproduction GO:0000003 245 0.032
organophosphate metabolic process GO:0019637 370 0.032
regulation of membrane potential GO:0042391 110 0.032
regulation of multicellular organismal development GO:2000026 376 0.031
anion transport GO:0006820 178 0.031
regulation of apoptotic process GO:0042981 335 0.031
multicellular organism reproduction GO:0032504 233 0.030
regulation of secretion GO:0051046 224 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
cation transport GO:0006812 382 0.030
regulation of secretion by cell GO:1903530 208 0.030
positive regulation of response to stimulus GO:0048584 285 0.029
response to biotic stimulus GO:0009607 226 0.029
oxoacid metabolic process GO:0043436 290 0.029
organic acid metabolic process GO:0006082 292 0.029
regulation of cell adhesion GO:0030155 52 0.029
regulation of cellular component organization GO:0051128 368 0.029
positive regulation of signal transduction GO:0009967 175 0.028
positive regulation of protein metabolic process GO:0051247 178 0.028
positive regulation of cell development GO:0010720 176 0.028
negative regulation of metabolic process GO:0009892 331 0.028
ribonucleotide catabolic process GO:0009261 136 0.027
programmed cell death GO:0012501 392 0.027
divalent inorganic cation transport GO:0072511 134 0.027
cellular ketone metabolic process GO:0042180 51 0.027
ribose phosphate metabolic process GO:0019693 235 0.026
cellular nitrogen compound catabolic process GO:0044270 163 0.026
positive regulation of locomotion GO:0040017 102 0.026
regulation of cellular protein metabolic process GO:0032268 267 0.026
regulation of protein localization GO:0032880 81 0.026
purine nucleoside triphosphate catabolic process GO:0009146 122 0.025
chemical homeostasis GO:0048878 292 0.025
response to extracellular stimulus GO:0009991 380 0.024
nucleotide metabolic process GO:0009117 279 0.024
regulation of immune system process GO:0002682 123 0.024
synaptic transmission GO:0007268 235 0.024
nucleobase containing compound catabolic process GO:0034655 152 0.024
positive regulation of immune system process GO:0002684 90 0.024
central nervous system development GO:0007417 311 0.023
secretion by cell GO:0032940 248 0.023
regulation of cellular localization GO:0060341 263 0.023
organic acid transport GO:0015849 116 0.023
inflammatory response GO:0006954 150 0.023
cell motility GO:0048870 202 0.023
neuron differentiation GO:0030182 368 0.023
Zebrafish
positive regulation of cell adhesion GO:0045785 30 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
peptidyl amino acid modification GO:0018193 126 0.022
negative regulation of protein metabolic process GO:0051248 114 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
endocytosis GO:0006897 84 0.022
regulation of endocytosis GO:0030100 42 0.022
homeostatic process GO:0042592 331 0.022
nucleotide catabolic process GO:0009166 139 0.022
neuron projection development GO:0031175 273 0.022
Zebrafish
calcium ion homeostasis GO:0055074 162 0.021
carboxylic acid metabolic process GO:0019752 289 0.021
nitrogen compound transport GO:0071705 229 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
circulatory system process GO:0003013 183 0.021
female pregnancy GO:0007565 122 0.021
regulation of synaptic transmission GO:0050804 141 0.021
carbohydrate metabolic process GO:0005975 130 0.021
head development GO:0060322 247 0.021
neuron development GO:0048666 286 0.021
Zebrafish
positive regulation of nervous system development GO:0051962 178 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
blood circulation GO:0008015 183 0.020
aromatic compound catabolic process GO:0019439 168 0.020
single organism catabolic process GO:0044712 283 0.020
organophosphate catabolic process GO:0046434 148 0.020
negative regulation of cell death GO:0060548 229 0.020
organelle organization GO:0006996 266 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.020
immune system process GO:0002376 204 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
positive regulation of catabolic process GO:0009896 78 0.020
sexual reproduction GO:0019953 148 0.019
reproductive system development GO:0061458 128 0.019
purine nucleoside catabolic process GO:0006152 124 0.019
rna metabolic process GO:0016070 406 0.019
gland development GO:0048732 155 0.019
cellular protein localization GO:0034613 122 0.019
antigen processing and presentation GO:0019882 2 0.019
response to molecule of bacterial origin GO:0002237 194 0.019
positive regulation of secretion GO:0051047 140 0.019
negative regulation of secretion by cell GO:1903531 72 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
regulation of nervous system development GO:0051960 264 0.018
regulation of cellular component movement GO:0051270 150 0.018
protein targeting GO:0006605 61 0.018
carboxylic acid transport GO:0046942 115 0.018
regulation of catabolic process GO:0009894 113 0.018
renal system development GO:0072001 67 0.018
response to decreased oxygen levels GO:0036293 237 0.018
cell type specific apoptotic process GO:0097285 134 0.018
developmental process involved in reproduction GO:0003006 159 0.018
amine metabolic process GO:0009308 38 0.018
positive regulation of cell death GO:0010942 184 0.018
negative regulation of gene expression GO:0010629 199 0.018
purine nucleoside monophosphate catabolic process GO:0009128 55 0.017
cellular chemical homeostasis GO:0055082 247 0.017
positive regulation of developmental process GO:0051094 283 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
regulation of transcription dna templated GO:0006355 374 0.017
regulation of immune response GO:0050776 55 0.017
cell projection morphogenesis GO:0048858 123 0.017
Zebrafish
regulation of neuron projection development GO:0010975 161 0.017
calcium ion transport GO:0006816 131 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
membrane organization GO:0061024 94 0.017
regulation of homeostatic process GO:0032844 101 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
regulation of neuron differentiation GO:0045664 208 0.017
cellular amine metabolic process GO:0044106 38 0.016
apoptotic process GO:0006915 381 0.016
regulation of neurogenesis GO:0050767 247 0.016
cell projection organization GO:0030030 302 0.016
Zebrafish
response to nutrient levels GO:0031667 370 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
regulation of response to wounding GO:1903034 69 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
positive regulation of nucleotide metabolic process GO:0045981 91 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
regulation of phosphorylation GO:0042325 248 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
cell cell signaling GO:0007267 335 0.016
positive regulation of protein modification process GO:0031401 142 0.016
regulation of signal transduction GO:0009966 318 0.015
regulation of cell development GO:0060284 263 0.015
response to external biotic stimulus GO:0043207 221 0.015
response to other organism GO:0051707 220 0.015
positive regulation of signaling GO:0023056 270 0.015
regulation of blood pressure GO:0008217 83 0.015
sex differentiation GO:0007548 113 0.015
regulation of body fluid levels GO:0050878 90 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
positive regulation of ion transport GO:0043270 94 0.015
cellular response to endogenous stimulus GO:0071495 377 0.015
intracellular signal transduction GO:0035556 314 0.015
cellular ion homeostasis GO:0006873 184 0.015
action potential GO:0001508 54 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
neuronal action potential GO:0019228 35 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
response to acid chemical GO:0001101 222 0.015
regulation of defense response GO:0031347 68 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
atp catabolic process GO:0006200 54 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.014
negative regulation of cellular metabolic process GO:0031324 281 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
heterocycle catabolic process GO:0046700 167 0.014
regulation of hormone levels GO:0010817 187 0.014
ion transmembrane transport GO:0034220 365 0.014
regulation of muscle cell apoptotic process GO:0010660 26 0.014
myelination GO:0042552 39 0.014
regulation of establishment of protein localization GO:0070201 69 0.014
defense response GO:0006952 194 0.014
regulation of protein modification process GO:0031399 194 0.014
response to hypoxia GO:0001666 231 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
reproductive structure development GO:0048608 128 0.014
lipid transport GO:0006869 61 0.014
response to peptide GO:1901652 292 0.014
response to nutrient GO:0007584 248 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
nucleoside monophosphate metabolic process GO:0009123 93 0.014
single organism cellular localization GO:1902580 102 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
nucleoside monophosphate catabolic process GO:0009125 56 0.014
regulation of cell projection organization GO:0031344 175 0.014
positive regulation of phosphorylation GO:0042327 177 0.013
cellular lipid metabolic process GO:0044255 208 0.013
protein complex subunit organization GO:0071822 302 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
macromolecule catabolic process GO:0009057 58 0.013
negative regulation of innate immune response GO:0045824 4 0.013
negative regulation of transport GO:0051051 136 0.013
exocytosis GO:0006887 60 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
transmission of nerve impulse GO:0019226 42 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
smooth muscle cell proliferation GO:0048659 77 0.013
behavior GO:0007610 205 0.013
response to growth factor GO:0070848 189 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
brain development GO:0007420 247 0.013
positive regulation of cell communication GO:0010647 271 0.013
gonad development GO:0008406 104 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
ribonucleotide biosynthetic process GO:0009260 85 0.012
eye development GO:0001654 50 0.012
hormone metabolic process GO:0042445 69 0.012
response to corticosteroid GO:0031960 235 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
blood vessel morphogenesis GO:0048514 58 0.012
regulation of metal ion transport GO:0010959 118 0.012
male gamete generation GO:0048232 99 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.012
tolerance induction dependent upon immune response GO:0002461 2 0.012
response to inorganic substance GO:0010035 377 0.012
peptide transport GO:0015833 97 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
protein complex biogenesis GO:0070271 263 0.012
spermatogenesis GO:0007283 99 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
dna metabolic process GO:0006259 96 0.012
negative regulation of secretion GO:0051048 82 0.012
ion homeostasis GO:0050801 212 0.012
nucleoside catabolic process GO:0009164 126 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.012
cellular response to external stimulus GO:0071496 118 0.012
organic hydroxy compound transport GO:0015850 77 0.012
atp metabolic process GO:0046034 72 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
nucleoside metabolic process GO:0009116 179 0.012
cation homeostasis GO:0055080 195 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.012
programmed necrotic cell death GO:0097300 2 0.012
rna biosynthetic process GO:0032774 380 0.012
neurological system process GO:0050877 219 0.012
regulation of programmed cell death GO:0043067 341 0.012
purine containing compound catabolic process GO:0072523 138 0.011
response to oxygen levels GO:0070482 265 0.011
development of primary sexual characteristics GO:0045137 107 0.011
cellular component assembly GO:0022607 360 0.011
response to ethanol GO:0045471 162 0.011
hepaticobiliary system development GO:0061008 90 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
positive regulation of biosynthetic process GO:0009891 319 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
response to wounding GO:0009611 254 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
golgi vesicle transport GO:0048193 22 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of protein transport GO:0051223 68 0.011
regulation of cell differentiation GO:0045595 320 0.011
response to peptide hormone GO:0043434 278 0.011
regulation of molecular function GO:0065009 398 0.011
tissue development GO:0009888 252 0.011
regeneration GO:0031099 163 0.011
cellular component biogenesis GO:0044085 368 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
metal ion homeostasis GO:0055065 186 0.011
positive regulation of cell killing GO:0031343 9 0.011
intra golgi vesicle mediated transport GO:0006891 3 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
positive regulation of endocytosis GO:0045807 28 0.011
response to bacterium GO:0009617 200 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
single organism biosynthetic process GO:0044711 342 0.010
cellular homeostasis GO:0019725 252 0.010
cellular response to lipid GO:0071396 201 0.010
ribose phosphate biosynthetic process GO:0046390 87 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
forebrain development GO:0030900 98 0.010
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
organ morphogenesis GO:0009887 75 0.010

Asah1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.045
disease of anatomical entity DOID:7 0 0.045
disease of metabolism DOID:0014667 0 0.020
eye and adnexa disease DOID:1492 0 0.012
sensory system disease DOID:0050155 0 0.012
eye disease DOID:5614 0 0.012
inherited metabolic disorder DOID:655 0 0.012