Rattus norvegicus

2 known processes

Pla2g10

phospholipase A2, group X

(Aliases: sPLA2-X,PLA2GX)

Pla2g10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.389
anion transport GO:0006820 178 0.342
Human Rat
regulation of ion transport GO:0043269 245 0.305
Human
metal ion transport GO:0030001 289 0.202
monovalent inorganic cation transport GO:0015672 172 0.176
regulation of secretion by cell GO:1903530 208 0.137
negative regulation of cell death GO:0060548 229 0.128
transmembrane transport GO:0055085 412 0.120
regulation of transcription dna templated GO:0006355 374 0.119
Human
organic acid metabolic process GO:0006082 292 0.118
Rat
hormone secretion GO:0046879 115 0.102
regulation of leukocyte activation GO:0002694 45 0.098
Human
regulation of catalytic activity GO:0050790 304 0.097
protein phosphorylation GO:0006468 345 0.087
response to acid chemical GO:0001101 222 0.083
cation transmembrane transport GO:0098655 263 0.080
muscle system process GO:0003012 115 0.079
inorganic cation transmembrane transport GO:0098662 202 0.078
apoptotic process GO:0006915 381 0.077
cellular ion homeostasis GO:0006873 184 0.076
carbohydrate derivative metabolic process GO:1901135 346 0.072
amine metabolic process GO:0009308 38 0.070
Rat
positive regulation of transport GO:0051050 245 0.069
Human
transcription dna templated GO:0006351 377 0.066
Human
negative regulation of programmed cell death GO:0043069 183 0.066
chemical homeostasis GO:0048878 292 0.066
calcium ion transport GO:0006816 131 0.062
regulation of phosphorylation GO:0042325 248 0.062
cellular amine metabolic process GO:0044106 38 0.061
Rat
carboxylic acid metabolic process GO:0019752 289 0.060
Rat
response to ketone GO:1901654 182 0.059
single organism intracellular transport GO:1902582 166 0.058
programmed cell death GO:0012501 392 0.058
response to estradiol GO:0032355 164 0.057
behavior GO:0007610 205 0.056
regulation of protein metabolic process GO:0051246 289 0.055
Human
response to peptide hormone GO:0043434 278 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.054
Rat
regulation of apoptotic process GO:0042981 335 0.053
regulation of programmed cell death GO:0043067 341 0.051
learning or memory GO:0007611 90 0.051
protein oligomerization GO:0051259 191 0.050
homeostatic process GO:0042592 331 0.049
negative regulation of apoptotic process GO:0043066 181 0.048
positive regulation of ion transport GO:0043270 94 0.048
Human
stress activated protein kinase signaling cascade GO:0031098 37 0.048
transcription from rna polymerase ii promoter GO:0006366 252 0.047
regulation of cellular ketone metabolic process GO:0010565 27 0.047
ion homeostasis GO:0050801 212 0.047
negative regulation of transport GO:0051051 136 0.045
regulation of cellular localization GO:0060341 263 0.045
positive regulation of signal transduction GO:0009967 175 0.044
regulation of neurogenesis GO:0050767 247 0.044
striatum development GO:0021756 2 0.044
regulation of molecular function GO:0065009 398 0.044
Human
regulation of metal ion transport GO:0010959 118 0.044
reproductive process GO:0022414 372 0.043
regulation of cellular amine metabolic process GO:0033238 8 0.043
regulation of hormone levels GO:0010817 187 0.042
positive regulation of biosynthetic process GO:0009891 319 0.041
Rat
neurological system process GO:0050877 219 0.041
potassium ion transport GO:0006813 97 0.041
response to hypoxia GO:0001666 231 0.040
positive regulation of developmental process GO:0051094 283 0.040
response to wounding GO:0009611 254 0.040
regulation of cellular protein metabolic process GO:0032268 267 0.039
Human
protein complex subunit organization GO:0071822 302 0.039
oxoacid metabolic process GO:0043436 290 0.039
Rat
intracellular transport GO:0046907 185 0.039
regulation of system process GO:0044057 208 0.039
mapk cascade GO:0000165 140 0.039
renal system process GO:0003014 40 0.039
cellular ketone metabolic process GO:0042180 51 0.038
negative regulation of metabolic process GO:0009892 331 0.038
locomotion GO:0040011 237 0.038
Human
ovulation cycle GO:0042698 67 0.038
regulation of cell proliferation GO:0042127 359 0.038
cellular response to oxygen containing compound GO:1901701 386 0.037
regulation of calcium ion transport GO:0051924 77 0.037
intracellular signal transduction GO:0035556 314 0.037
synaptic transmission GO:0007268 235 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.036
response to peptide GO:1901652 292 0.036
positive regulation of protein metabolic process GO:0051247 178 0.035
Human
purine containing compound metabolic process GO:0072521 253 0.035
macromolecule localization GO:0033036 252 0.034
Human Rat
positive regulation of cell communication GO:0010647 271 0.033
single organism behavior GO:0044708 130 0.032
regulation of cell differentiation GO:0045595 320 0.032
ion transmembrane transport GO:0034220 365 0.032
response to other organism GO:0051707 220 0.032
antibiotic transport GO:0042891 2 0.031
regulation of homeostatic process GO:0032844 101 0.031
ribonucleotide metabolic process GO:0009259 231 0.030
nucleotide catabolic process GO:0009166 139 0.030
cellular cation homeostasis GO:0030003 180 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
protein complex biogenesis GO:0070271 263 0.029
regulation of membrane potential GO:0042391 110 0.029
circulatory system development GO:0072359 134 0.029
development of primary female sexual characteristics GO:0046545 56 0.029
muscle contraction GO:0006936 88 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
positive regulation of kinase activity GO:0033674 77 0.028
organonitrogen compound biosynthetic process GO:1901566 167 0.028
Rat
positive regulation of cell proliferation GO:0008284 249 0.028
regulation of purine nucleotide metabolic process GO:1900542 115 0.027
sensory perception GO:0007600 101 0.026
cognition GO:0050890 92 0.026
protein complex assembly GO:0006461 263 0.026
regulation of blood circulation GO:1903522 110 0.026
positive regulation of calcium ion transport GO:0051928 36 0.026
signal transduction by phosphorylation GO:0023014 144 0.026
reproduction GO:0000003 245 0.025
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.025
organic anion transport GO:0015711 132 0.025
Human Rat
organelle organization GO:0006996 266 0.025
multicellular organism reproduction GO:0032504 233 0.025
regulation of inflammatory response GO:0050727 48 0.025
defense response GO:0006952 194 0.025
g protein coupled receptor signaling pathway GO:0007186 242 0.025
regulation of cell migration GO:0030334 128 0.024
cytoplasmic transport GO:0016482 115 0.024
inflammatory response GO:0006954 150 0.024
response to estrogen GO:0043627 232 0.024
regulation of epithelial cell proliferation GO:0050678 49 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
rhythmic process GO:0048511 156 0.024
response to ph GO:0009268 27 0.024
regulation of response to external stimulus GO:0032101 106 0.024
regulation of protein phosphorylation GO:0001932 183 0.023
negative regulation of cell communication GO:0010648 158 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
rna biosynthetic process GO:0032774 380 0.023
Human
peptidyl amino acid modification GO:0018193 126 0.023
regulation of secretion GO:0051046 224 0.023
Human
nitrogen compound transport GO:0071705 229 0.023
response to external biotic stimulus GO:0043207 221 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
cellular chemical homeostasis GO:0055082 247 0.023
cellular homeostasis GO:0019725 252 0.022
secretion GO:0046903 307 0.022
Human Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
memory GO:0007613 54 0.021
negative regulation of signaling GO:0023057 157 0.021
cellular nitrogen compound catabolic process GO:0044270 163 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
Rat
regulation of muscle system process GO:0090257 79 0.021
regulation of kinase activity GO:0043549 117 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
protein localization GO:0008104 191 0.021
cellular component biogenesis GO:0044085 368 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
hormone transport GO:0009914 121 0.020
macromolecular complex assembly GO:0065003 273 0.020
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.020
sodium ion transmembrane transport GO:0035725 67 0.020
positive regulation of saliva secretion GO:0046878 3 0.020
amide transport GO:0042886 105 0.020
response to toxic substance GO:0009636 133 0.020
cell cell signaling GO:0007267 335 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
peptide transport GO:0015833 97 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
nucleotide biosynthetic process GO:0009165 98 0.019
regulation of ion homeostasis GO:2000021 63 0.019
regulation of cellular component organization GO:0051128 368 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
response to glucocorticoid GO:0051384 223 0.019
carnitine transport GO:0015879 1 0.019
response to ammonium ion GO:0060359 71 0.019
positive regulation of molecular function GO:0044093 230 0.019
rna metabolic process GO:0016070 406 0.019
Human
positive regulation of cell differentiation GO:0045597 217 0.018
actin cytoskeleton organization GO:0030036 73 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
Human
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
single organism cellular localization GO:1902580 102 0.018
response to oxygen levels GO:0070482 265 0.018
positive regulation of nervous system development GO:0051962 178 0.018
cellular response to stress GO:0033554 269 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
regulation of hydrolase activity GO:0051336 143 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
regulation of protein maturation GO:1903317 50 0.018
protein processing GO:0016485 68 0.018
regulation of smooth muscle cell proliferation GO:0048660 75 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
Rat
regulation of protein kinase activity GO:0045859 105 0.018
cytoskeleton organization GO:0007010 111 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
carbohydrate metabolic process GO:0005975 130 0.017
cellular protein localization GO:0034613 122 0.017
regulation of jnk cascade GO:0046328 19 0.017
response to decreased oxygen levels GO:0036293 237 0.017
regeneration GO:0031099 163 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
Human
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
growth GO:0040007 165 0.017
sodium independent organic anion transport GO:0043252 2 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
muscle cell proliferation GO:0033002 84 0.017
single organism biosynthetic process GO:0044711 342 0.017
Rat
regulation of defecation GO:2000292 1 0.016
negative regulation of gene expression GO:0010629 199 0.016
single organism organelle organization GO:1902589 180 0.016
positive regulation of blood circulation GO:1903524 65 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
regulation of cell activation GO:0050865 50 0.016
Human
negative regulation of catalytic activity GO:0043086 103 0.016
multi multicellular organism process GO:0044706 138 0.016
single organism reproductive process GO:0044702 297 0.016
female sex differentiation GO:0046660 59 0.016
regulation of acute inflammatory response GO:0002673 23 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
regulation of transmembrane transport GO:0034762 122 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
response to electrical stimulus GO:0051602 56 0.016
positive regulation of protein modification process GO:0031401 142 0.016
heart process GO:0003015 57 0.016
response to cytokine GO:0034097 215 0.015
Rat
reproductive system development GO:0061458 128 0.015
regulation of cellular response to stress GO:0080135 49 0.015
regulation of nervous system development GO:0051960 264 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.015
regulation of neuron differentiation GO:0045664 208 0.015
negative regulation of hormone secretion GO:0046888 46 0.015
positive regulation of cell motility GO:2000147 97 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
regulation of defense response GO:0031347 68 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
Human
regulation of cell development GO:0060284 263 0.014
positive regulation of signaling GO:0023056 270 0.014
regulation of cell projection organization GO:0031344 175 0.014
positive regulation of epithelial cell proliferation GO:0050679 32 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
negative regulation of protein processing GO:0010955 47 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
negative regulation of signal transduction GO:0009968 83 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
regulation of response to wounding GO:1903034 69 0.014
amine transport GO:0015837 57 0.014
regulation of response to stress GO:0080134 126 0.014
carboxylic acid biosynthetic process GO:0046394 83 0.014
Rat
epithelial cell proliferation GO:0050673 54 0.014
nucleic acid templated transcription GO:0097659 379 0.014
Human
vasodilation GO:0042311 44 0.014
actin filament based process GO:0030029 86 0.013
response to calcium ion GO:0051592 59 0.013
stress activated mapk cascade GO:0051403 35 0.013
endocrine process GO:0050886 32 0.013
regulation of lyase activity GO:0051339 22 0.013
regulation of rna metabolic process GO:0051252 391 0.013
Human
negative regulation of protein metabolic process GO:0051248 114 0.013
positive regulation of transferase activity GO:0051347 81 0.013
regulation of potassium ion transport GO:0043266 29 0.013
positive regulation of gene expression GO:0010628 244 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
gonad development GO:0008406 104 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
response to nutrient levels GO:0031667 370 0.013
regulation of peptide transport GO:0090087 87 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
ovulation cycle process GO:0022602 50 0.013
positive regulation of protein kinase activity GO:0045860 73 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
divalent inorganic cation transport GO:0072511 134 0.013
response to metal ion GO:0010038 253 0.012
neuron projection development GO:0031175 273 0.012
Human
response to antibiotic GO:0046677 39 0.012
response to ethanol GO:0045471 162 0.012
organic acid transport GO:0015849 116 0.012
Human Rat
response to oxidative stress GO:0006979 186 0.012
sterol homeostasis GO:0055092 3 0.012
immune system process GO:0002376 204 0.012
Human
regulation of cellular component movement GO:0051270 150 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
cellular response to oxygen levels GO:0071453 60 0.012
nucleoside metabolic process GO:0009116 179 0.012
nucleocytoplasmic transport GO:0006913 48 0.012
cellular component assembly GO:0022607 360 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
action potential GO:0001508 54 0.012
aging GO:0007568 241 0.012
protein transport GO:0015031 132 0.012
positive regulation of cell development GO:0010720 176 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
regulation of intracellular transport GO:0032386 65 0.012
response to growth factor GO:0070848 189 0.012
central nervous system development GO:0007417 311 0.012
cellular macromolecule localization GO:0070727 122 0.012
positive regulation of somatostatin secretion GO:0090274 4 0.012
respiratory system development GO:0060541 45 0.012
response to testosterone GO:0033574 55 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.011
heart contraction GO:0060047 57 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
regulation of anatomical structure size GO:0090066 135 0.011
cell growth GO:0016049 104 0.011
response to radiation GO:0009314 137 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
establishment of protein localization GO:0045184 141 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
Human
multicellular organismal response to stress GO:0033555 25 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
regulation of growth GO:0040008 105 0.011
response to molecule of fungal origin GO:0002238 3 0.011
response to alkaloid GO:0043279 132 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
regulation of protein processing GO:0070613 50 0.011
dna metabolic process GO:0006259 96 0.011
Rat
cellular response to acid chemical GO:0071229 75 0.011
smooth muscle contraction GO:0006939 37 0.011
adult behavior GO:0030534 16 0.011
catabolic process GO:0009056 351 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
positive regulation of response to wounding GO:1903036 34 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
adult locomotory behavior GO:0008344 4 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
regulation of neuron projection development GO:0010975 161 0.011
metal ion homeostasis GO:0055065 186 0.010
organic acid biosynthetic process GO:0016053 83 0.010
Rat
response to extracellular stimulus GO:0009991 380 0.010
regulation of cell growth GO:0001558 85 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.010
monocarboxylic acid transport GO:0015718 52 0.010
Human Rat
circulatory system process GO:0003013 183 0.010
regulation of stress activated mapk cascade GO:0032872 23 0.010
renal sodium excretion GO:0035812 20 0.010
regulation of body fluid levels GO:0050878 90 0.010
macromolecule catabolic process GO:0009057 58 0.010
calcium ion homeostasis GO:0055074 162 0.010
positive regulation of homeostatic process GO:0032846 49 0.010
positive regulation of phosphate metabolic process GO:0045937 262 0.010

Pla2g10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
central nervous system disease DOID:331 0 0.016
connective tissue disease DOID:65 0 0.010
musculoskeletal system disease DOID:17 0 0.010