Caenorhabditis elegans

0 known processes

polk-1 (CELE_F22B7.6)

Protein POLK-1

polk-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.545
vesicle mediated transport GO:0016192 852 0.356
endocytosis GO:0006897 819 0.303
embryo development ending in birth or egg hatching GO:0009792 2992 0.297
establishment of localization GO:0051234 1171 0.287
macromolecule biosynthetic process GO:0009059 250 0.243
organ development GO:0048513 1102 0.235
vulval development GO:0040025 333 0.229
embryo development GO:0009790 3052 0.226
transport GO:0006810 1093 0.212
cell cycle GO:0007049 526 0.179
cell death GO:0008219 547 0.173
regulation of multicellular organismal process GO:0051239 726 0.171
cellular protein modification process GO:0006464 207 0.170
cell cell signaling GO:0007267 118 0.160
protein modification process GO:0036211 207 0.152
regulation of developmental process GO:0050793 684 0.146
female gamete generation GO:0007292 254 0.145
programmed cell death GO:0012501 500 0.141
nucleic acid metabolic process GO:0090304 299 0.133
biosynthetic process GO:0009058 323 0.133
meiotic nuclear division GO:0007126 300 0.129
regulation of multicellular organismal development GO:2000026 317 0.127
signaling GO:0023052 401 0.121
receptor mediated endocytosis GO:0006898 715 0.121
nucleobase containing compound metabolic process GO:0006139 406 0.118
developmental process involved in reproduction GO:0003006 1165 0.117
meiotic cell cycle GO:0051321 335 0.116
determination of adult lifespan GO:0008340 812 0.109
macromolecule modification GO:0043412 218 0.107
growth GO:0040007 562 0.107
regulation of macromolecule metabolic process GO:0060255 421 0.106
apoptotic process GO:0006915 478 0.104
regulation of biosynthetic process GO:0009889 189 0.102
regulation of biological quality GO:0065008 741 0.100
regulation of gene expression epigenetic GO:0040029 163 0.095
cellular biosynthetic process GO:0044249 315 0.094
regulation of nitrogen compound metabolic process GO:0051171 222 0.092
sex differentiation GO:0007548 909 0.092
single organism signaling GO:0044700 401 0.091
aging GO:0007568 812 0.089
rna metabolic process GO:0016070 228 0.086
post embryonic organ development GO:0048569 336 0.082
negative regulation of metabolic process GO:0009892 240 0.079
multicellular organismal reproductive process GO:0048609 815 0.079
organic substance biosynthetic process GO:1901576 323 0.079
single organism transport GO:0044765 447 0.078
mitotic cell cycle process GO:1903047 194 0.075
negative regulation of gene expression GO:0010629 217 0.075
macromolecule localization GO:0033036 771 0.073
synaptic transmission GO:0007268 106 0.072
multi organism reproductive process GO:0044703 867 0.071
regulation of growth GO:0040008 409 0.070
behavior GO:0007610 527 0.067
multicellular organismal reproductive behavior GO:0033057 384 0.067
development of primary sexual characteristics GO:0045137 840 0.066
lipid localization GO:0010876 573 0.066
regulation of nematode larval development GO:0061062 260 0.065
regulation of gene expression GO:0010468 366 0.065
cellular macromolecule biosynthetic process GO:0034645 247 0.064
regulation of metabolic process GO:0019222 478 0.062
single organism localization GO:1902578 518 0.061
lipid storage GO:0019915 565 0.061
cellular protein metabolic process GO:0044267 279 0.061
reproductive structure development GO:0048608 850 0.060
negative regulation of macromolecule metabolic process GO:0010605 229 0.060
negative regulation of developmental process GO:0051093 227 0.060
maintenance of location GO:0051235 580 0.059
regulation of macromolecule biosynthetic process GO:0010556 189 0.057
gene expression GO:0010467 412 0.055
gamete generation GO:0007276 461 0.055
regulation of transcription dna templated GO:0006355 164 0.055
cell motility GO:0048870 313 0.054
multicellular organismal aging GO:0010259 812 0.053
genitalia development GO:0048806 741 0.053
phosphorylation GO:0016310 116 0.052
organic cyclic compound biosynthetic process GO:1901362 195 0.051
single organism reproductive process GO:0044702 1196 0.051
sexual reproduction GO:0019953 546 0.049
hermaphrodite genitalia development GO:0040035 734 0.048
negative regulation of multicellular organismal process GO:0051241 236 0.048
reproductive system development GO:0061458 850 0.048
positive regulation of developmental process GO:0051094 408 0.047
localization of cell GO:0051674 313 0.047
oogenesis GO:0048477 229 0.047
cell development GO:0048468 696 0.046
regulation of cellular biosynthetic process GO:0031326 189 0.044
multicellular organism reproduction GO:0032504 819 0.043
regulation of post embryonic development GO:0048580 260 0.042
protein metabolic process GO:0019538 422 0.042
gene silencing GO:0016458 143 0.042
generation of neurons GO:0048699 235 0.041
multi organism reproductive behavior GO:0044705 387 0.040
reproductive behavior GO:0019098 387 0.040
negative regulation of nematode larval development GO:0061064 208 0.040
cell cycle process GO:0022402 482 0.038
death GO:0016265 547 0.037
locomotion GO:0040011 1634 0.037
positive regulation of growth GO:0045927 369 0.037
single organism organelle organization GO:1902589 501 0.037
positive regulation of multicellular organism growth GO:0040018 352 0.036
tissue development GO:0009888 112 0.036
regulation of primary metabolic process GO:0080090 292 0.036
gonad development GO:0008406 840 0.036
transcription dna templated GO:0006351 168 0.035
multi organism behavior GO:0051705 389 0.035
regulation of vulval development GO:0040028 248 0.034
small molecule metabolic process GO:0044281 186 0.033
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.033
regulation of developmental growth GO:0048638 389 0.033
chromosome organization involved in meiosis GO:0070192 25 0.033
cellular response to stress GO:0033554 162 0.031
negative regulation of post embryonic development GO:0048581 208 0.031
multi multicellular organism process GO:0044706 390 0.030
negative regulation of biological process GO:0048519 567 0.029
nervous system development GO:0007399 253 0.029
gene silencing by rna GO:0031047 143 0.029
regulation of cellular metabolic process GO:0031323 305 0.028
multicellular organism growth GO:0035264 385 0.027
developmental growth GO:0048589 412 0.027
single organism biosynthetic process GO:0044711 91 0.027
anatomical structure homeostasis GO:0060249 11 0.027
cellular component movement GO:0006928 388 0.026
cellular nitrogen compound biosynthetic process GO:0044271 192 0.026
body morphogenesis GO:0010171 620 0.025
neurogenesis GO:0022008 236 0.025
positive regulation of neurogenesis GO:0050769 4 0.025
regulation of multicellular organism growth GO:0040014 373 0.025
regulation of cell cycle GO:0051726 194 0.025
meiotic chromosome segregation GO:0045132 139 0.024
posttranscriptional regulation of gene expression GO:0010608 166 0.024
positive regulation of cell projection organization GO:0031346 4 0.024
epithelium development GO:0060429 68 0.024
homeostatic process GO:0042592 51 0.024
heterocycle biosynthetic process GO:0018130 187 0.024
cytoskeleton organization GO:0007010 339 0.023
muscle structure development GO:0061061 191 0.023
nucleobase containing small molecule metabolic process GO:0055086 115 0.023
oviposition GO:0018991 364 0.023
nucleic acid templated transcription GO:0097659 169 0.023
phagocytosis engulfment GO:0006911 98 0.022
phosphate containing compound metabolic process GO:0006796 232 0.022
response to abiotic stimulus GO:0009628 152 0.021
cellular response to organic substance GO:0071310 119 0.021
phagocytosis GO:0006909 115 0.021
actin cytoskeleton organization GO:0030036 184 0.021
regulation of rna biosynthetic process GO:2001141 165 0.021
cellular localization GO:0051641 360 0.021
nucleoside phosphate metabolic process GO:0006753 108 0.021
germ cell development GO:0007281 351 0.020
apoptotic cell clearance GO:0043277 111 0.020
response to organic substance GO:0010033 131 0.020
organic substance catabolic process GO:1901575 294 0.020
response to chemical GO:0042221 356 0.020
organonitrogen compound catabolic process GO:1901565 90 0.020
posttranscriptional gene silencing by rna GO:0035194 143 0.019
positive regulation of cellular process GO:0048522 332 0.019
synaptic vesicle localization GO:0097479 22 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
negative regulation of cellular metabolic process GO:0031324 95 0.019
regulation of cell communication GO:0010646 176 0.019
protein complex subunit organization GO:0071822 280 0.019
positive regulation of multicellular organismal process GO:0051240 417 0.019
peptidyl tyrosine phosphorylation GO:0018108 2 0.019
head development GO:0060322 1 0.018
negative regulation of cellular process GO:0048523 239 0.018
engulfment of apoptotic cell GO:0043652 94 0.018
organophosphate metabolic process GO:0019637 125 0.018
nucleoside metabolic process GO:0009116 99 0.018
regulation of signaling GO:0023051 172 0.018
regulation of phosphorus metabolic process GO:0051174 81 0.018
protein phosphorylation GO:0006468 85 0.018
organelle fission GO:0048285 363 0.017
cell migration GO:0016477 306 0.017
rna interference GO:0016246 137 0.017
cell projection organization GO:0030030 231 0.017
epithelial cell proliferation GO:0050673 1 0.017
sensory organ morphogenesis GO:0090596 2 0.017
regulation of molecular function GO:0065009 89 0.017
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.017
positive regulation of developmental growth GO:0048639 354 0.017
digestive system development GO:0055123 122 0.017
positive regulation of neuron projection development GO:0010976 4 0.016
collagen and cuticulin based cuticle development GO:0040002 99 0.016
protein complex assembly GO:0006461 186 0.016
embryonic morphogenesis GO:0048598 152 0.016
nucleobase containing compound catabolic process GO:0034655 114 0.016
regulation of localization GO:0032879 194 0.016
membrane invagination GO:0010324 98 0.016
posttranscriptional gene silencing GO:0016441 143 0.016
cellular component biogenesis GO:0044085 297 0.016
establishment of organelle localization GO:0051656 123 0.016
cellular component assembly GO:0022607 293 0.016
regulation of purine nucleotide catabolic process GO:0033121 35 0.016
regulation of rna metabolic process GO:0051252 173 0.015
purine ribonucleoside metabolic process GO:0046128 92 0.015
regulation of signal transduction GO:0009966 135 0.015
intracellular signal transduction GO:0035556 96 0.015
regulation of phosphorylation GO:0042325 45 0.015
adult locomotory behavior GO:0008344 1 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
negative regulation of biosynthetic process GO:0009890 65 0.015
neuromuscular junction development GO:0007528 2 0.015
nucleoside catabolic process GO:0009164 78 0.015
digestive tract morphogenesis GO:0048546 76 0.014
cell division GO:0051301 262 0.014
secretion GO:0046903 147 0.014
regulation of transport GO:0051049 91 0.014
cell cycle phase transition GO:0044770 19 0.014
muscle cell development GO:0055001 158 0.014
membrane organization GO:0061024 135 0.014
regulation of response to stimulus GO:0048583 243 0.014
myosin filament organization GO:0031033 138 0.013
negative regulation of vulval development GO:0040027 206 0.013
cell cycle g1 s phase transition GO:0044843 2 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
cytokinesis GO:0000910 80 0.013
nucleotide metabolic process GO:0009117 108 0.013
macromolecular complex subunit organization GO:0043933 320 0.013
neuron differentiation GO:0030182 217 0.013
rho protein signal transduction GO:0007266 2 0.013
establishment of localization in cell GO:0051649 318 0.013
digestive tract development GO:0048565 122 0.013
cell fate commitment GO:0045165 139 0.013
organelle organization GO:0006996 783 0.013
protein complex biogenesis GO:0070271 186 0.013
vesicle localization GO:0051648 24 0.013
establishment of vesicle localization GO:0051650 23 0.013
actin filament based process GO:0030029 191 0.013
cell substrate adhesion GO:0031589 1 0.012
oxoacid metabolic process GO:0043436 47 0.012
neuron projection development GO:0031175 187 0.012
cellular response to chemical stimulus GO:0070887 129 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
striated muscle cell differentiation GO:0051146 158 0.012
microtubule based process GO:0007017 182 0.012
glycosyl compound metabolic process GO:1901657 100 0.012
aromatic compound biosynthetic process GO:0019438 192 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.012
enzyme linked receptor protein signaling pathway GO:0007167 50 0.012
regulation of catalytic activity GO:0050790 78 0.012
cell surface receptor signaling pathway GO:0007166 149 0.012
rna biosynthetic process GO:0032774 169 0.012
phosphorus metabolic process GO:0006793 232 0.012
myosin filament assembly GO:0031034 138 0.012
nucleotide catabolic process GO:0009166 77 0.011
tissue morphogenesis GO:0048729 65 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
signal transduction GO:0007165 317 0.011
protein modification by small protein conjugation or removal GO:0070647 40 0.011
negative regulation of cellular biosynthetic process GO:0031327 65 0.011
dna metabolic process GO:0006259 74 0.011
regulation of intracellular signal transduction GO:1902531 77 0.011
developmental maturation GO:0021700 26 0.011
meiosis i GO:0007127 19 0.011
actomyosin structure organization GO:0031032 154 0.011
ribonucleoside triphosphate metabolic process GO:0009199 87 0.011
regulation of cellular component organization GO:0051128 248 0.011
positive regulation of cell cycle GO:0045787 55 0.011
regulation of nervous system development GO:0051960 41 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
regulation of phosphate metabolic process GO:0019220 81 0.011
myofibril assembly GO:0030239 154 0.010
organic acid metabolic process GO:0006082 47 0.010
positive regulation of chromosome organization GO:2001252 2 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
tube development GO:0035295 126 0.010
dna geometric change GO:0032392 3 0.010
cuticle development GO:0042335 100 0.010

polk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021