Caenorhabditis elegans

23 known processes

atx-3 (CELE_F28F8.6)

Protein ATX-3

atx-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.825
macromolecule catabolic process GO:0009057 202 0.494
Mouse
apoptotic process GO:0006915 478 0.481
ubiquitin dependent protein catabolic process GO:0006511 32 0.431
Mouse
embryo development ending in birth or egg hatching GO:0009792 2992 0.416
cell cycle process GO:0022402 482 0.410
locomotion GO:0040011 1634 0.388
cellular protein metabolic process GO:0044267 279 0.376
Mouse
single organism organelle organization GO:1902589 501 0.330
programmed cell death GO:0012501 500 0.317
cellular protein catabolic process GO:0044257 37 0.298
Mouse
cellular nitrogen compound catabolic process GO:0044270 119 0.287
mitotic cell cycle process GO:1903047 194 0.253
cellular catabolic process GO:0044248 199 0.252
Mouse
signal transduction GO:0007165 317 0.236
protein metabolic process GO:0019538 422 0.234
post embryonic development GO:0009791 2152 0.199
death GO:0016265 547 0.190
cell death GO:0008219 547 0.177
positive regulation of cellular process GO:0048522 332 0.174
organic substance catabolic process GO:1901575 294 0.172
Mouse
organelle organization GO:0006996 783 0.163
regulation of catabolic process GO:0009894 57 0.162
catabolic process GO:0009056 318 0.159
Mouse
chromosome organization GO:0051276 104 0.159
protein catabolic process GO:0030163 162 0.157
Mouse
establishment of localization GO:0051234 1171 0.153
regulation of cell communication GO:0010646 176 0.148
cell growth GO:0016049 44 0.148
purine nucleotide metabolic process GO:0006163 95 0.144
female gamete generation GO:0007292 254 0.143
modification dependent macromolecule catabolic process GO:0043632 32 0.142
Mouse
regulation of biological quality GO:0065008 741 0.139
regulation of macromolecule metabolic process GO:0060255 421 0.135
organ development GO:0048513 1102 0.132
determination of adult lifespan GO:0008340 812 0.131
single organism catabolic process GO:0044712 129 0.126
cell surface receptor signaling pathway GO:0007166 149 0.122
growth GO:0040007 562 0.119
cell projection morphogenesis GO:0048858 148 0.119
positive regulation of cellular metabolic process GO:0031325 178 0.117
single organism localization GO:1902578 518 0.115
cellular response to organic substance GO:0071310 119 0.113
Mouse
regulation of gene expression GO:0010468 366 0.112
proteolysis GO:0006508 61 0.111
cellular macromolecule catabolic process GO:0044265 73 0.111
Mouse
nucleobase containing compound catabolic process GO:0034655 114 0.110
oogenesis GO:0048477 229 0.107
aging GO:0007568 812 0.106
multicellular organismal aging GO:0010259 812 0.106
chromosome organization involved in meiosis GO:0070192 25 0.104
developmental process involved in reproduction GO:0003006 1165 0.104
organic substance biosynthetic process GO:1901576 323 0.102
cell development GO:0048468 696 0.097
cellular component assembly GO:0022607 293 0.096
single organism transport GO:0044765 447 0.093
signaling GO:0023052 401 0.092
negative regulation of metabolic process GO:0009892 240 0.090
reproductive system development GO:0061458 850 0.089
gene expression GO:0010467 412 0.089
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.088
Mouse
tissue development GO:0009888 112 0.087
cellular localization GO:0051641 360 0.086
gonad development GO:0008406 840 0.084
cell part morphogenesis GO:0032990 152 0.079
cell cycle GO:0007049 526 0.079
organic cyclic compound catabolic process GO:1901361 119 0.076
germ cell development GO:0007281 351 0.075
heterocycle catabolic process GO:0046700 119 0.074
chromosome segregation GO:0007059 180 0.074
reproductive structure development GO:0048608 850 0.073
regulation of catalytic activity GO:0050790 78 0.072
negative regulation of gene expression GO:0010629 217 0.071
modification dependent protein catabolic process GO:0019941 32 0.070
Mouse
positive regulation of macromolecule metabolic process GO:0010604 149 0.068
aromatic compound catabolic process GO:0019439 116 0.066
cellular component biogenesis GO:0044085 297 0.066
establishment of localization in cell GO:0051649 318 0.066
cell division GO:0051301 262 0.063
maintenance of location GO:0051235 580 0.061
regulation of developmental process GO:0050793 684 0.061
lipid storage GO:0019915 565 0.061
macromolecule localization GO:0033036 771 0.061
regulation of growth GO:0040008 409 0.060
positive regulation of multicellular organism growth GO:0040018 352 0.060
regulation of cellular catabolic process GO:0031329 51 0.059
regulation of multicellular organismal process GO:0051239 726 0.059
response to external stimulus GO:0009605 289 0.058
proteasomal protein catabolic process GO:0010498 20 0.058
Mouse
developmental growth GO:0048589 412 0.057
cellular protein modification process GO:0006464 207 0.057
Mouse
regulation of signaling GO:0023051 172 0.057
regulation of cellular component organization GO:0051128 248 0.056
lipid localization GO:0010876 573 0.055
ribonucleoside triphosphate catabolic process GO:0009203 72 0.054
regulation of organelle organization GO:0033043 164 0.054
generation of neurons GO:0048699 235 0.054
neurogenesis GO:0022008 236 0.054
negative regulation of biological process GO:0048519 567 0.053
cellular response to stress GO:0033554 162 0.053
Mouse
macromolecule modification GO:0043412 218 0.053
Mouse
body morphogenesis GO:0010171 620 0.053
sex differentiation GO:0007548 909 0.052
positive regulation of metabolic process GO:0009893 187 0.052
gene silencing GO:0016458 143 0.051
cytoskeleton organization GO:0007010 339 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.049
regulation of nitrogen compound metabolic process GO:0051171 222 0.047
single organism reproductive process GO:0044702 1196 0.047
regulation of cell division GO:0051302 142 0.047
posttranscriptional gene silencing GO:0016441 143 0.046
organophosphate catabolic process GO:0046434 81 0.046
gamete generation GO:0007276 461 0.046
positive regulation of catalytic activity GO:0043085 59 0.045
rna metabolic process GO:0016070 228 0.045
organelle fission GO:0048285 363 0.043
neuron differentiation GO:0030182 217 0.043
neuron development GO:0048666 199 0.043
dna metabolic process GO:0006259 74 0.043
positive regulation of developmental process GO:0051094 408 0.042
protein complex biogenesis GO:0070271 186 0.042
secretion by cell GO:0032940 138 0.042
hermaphrodite genitalia development GO:0040035 734 0.042
nucleoside catabolic process GO:0009164 78 0.041
single organism signaling GO:0044700 401 0.041
regulation of gene expression epigenetic GO:0040029 163 0.041
carbohydrate derivative catabolic process GO:1901136 82 0.041
regulation of response to stimulus GO:0048583 243 0.040
regulation of cellular metabolic process GO:0031323 305 0.040
purine ribonucleotide metabolic process GO:0009150 95 0.039
sexual reproduction GO:0019953 546 0.039
response to abiotic stimulus GO:0009628 152 0.039
Mouse
cellular protein complex assembly GO:0043623 178 0.039
multi organism reproductive process GO:0044703 867 0.039
sister chromatid segregation GO:0000819 46 0.038
neuron projection development GO:0031175 187 0.038
protein complex subunit organization GO:0071822 280 0.037
purine nucleoside triphosphate catabolic process GO:0009146 72 0.036
mitotic nuclear division GO:0007067 89 0.036
regulation of cellular protein metabolic process GO:0032268 75 0.036
regulation of metabolic process GO:0019222 478 0.035
phosphate containing compound metabolic process GO:0006796 232 0.035
gene silencing by rna GO:0031047 143 0.035
reproductive behavior GO:0019098 387 0.035
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.035
positive regulation of growth GO:0045927 369 0.033
carbohydrate derivative metabolic process GO:1901135 141 0.033
regulation of protein metabolic process GO:0051246 81 0.033
purine nucleoside triphosphate metabolic process GO:0009144 87 0.032
response to chemical GO:0042221 356 0.032
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.032
developmental cell growth GO:0048588 39 0.032
nervous system development GO:0007399 253 0.031
regulation of multicellular organismal development GO:2000026 317 0.031
macromolecular complex subunit organization GO:0043933 320 0.031
receptor mediated endocytosis GO:0006898 715 0.030
positive regulation of developmental growth GO:0048639 354 0.030
protein modification process GO:0036211 207 0.030
Mouse
multicellular organism growth GO:0035264 385 0.030
microtubule based process GO:0007017 182 0.030
nucleoside triphosphate catabolic process GO:0009143 72 0.030
cellular macromolecular complex assembly GO:0034622 184 0.030
axon development GO:0061564 163 0.030
negative regulation of developmental process GO:0051093 227 0.030
regulation of mitotic cell cycle GO:0007346 76 0.029
regulation of developmental growth GO:0048638 389 0.029
regulation of signal transduction GO:0009966 135 0.029
nucleic acid metabolic process GO:0090304 299 0.029
muscle structure development GO:0061061 191 0.029
neuron projection morphogenesis GO:0048812 114 0.028
transport GO:0006810 1093 0.027
chromatin remodeling GO:0006338 2 0.027
cellular component morphogenesis GO:0032989 318 0.027
negative regulation of macromolecule metabolic process GO:0010605 229 0.027
posttranscriptional regulation of gene expression GO:0010608 166 0.026
regulation of multicellular organism growth GO:0040014 373 0.026
rna interference GO:0016246 137 0.026
regulation of programmed cell death GO:0043067 50 0.025
negative regulation of cellular process GO:0048523 239 0.025
protein complex assembly GO:0006461 186 0.025
negative regulation of multicellular organismal process GO:0051241 236 0.025
nucleobase containing compound metabolic process GO:0006139 406 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.024
purine containing compound catabolic process GO:0072523 75 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.023
ribonucleoside catabolic process GO:0042454 77 0.023
development of primary sexual characteristics GO:0045137 840 0.023
nucleoside phosphate metabolic process GO:0006753 108 0.023
regulation of localization GO:0032879 194 0.023
protein localization GO:0008104 205 0.023
organelle localization GO:0051640 127 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.022
Mouse
lipid metabolic process GO:0006629 77 0.022
endocytosis GO:0006897 819 0.022
posttranscriptional gene silencing by rna GO:0035194 143 0.022
mitotic spindle organization GO:0007052 81 0.021
small gtpase mediated signal transduction GO:0007264 32 0.021
positive regulation of multicellular organismal process GO:0051240 417 0.021
nucleotide metabolic process GO:0009117 108 0.021
neuron projection guidance GO:0097485 82 0.021
genitalia development GO:0048806 741 0.020
positive regulation of chromosome organization GO:2001252 2 0.020
protein modification by small protein conjugation or removal GO:0070647 40 0.020
Mouse
synaptic transmission GO:0007268 106 0.020
regulation of rna metabolic process GO:0051252 173 0.020
purine ribonucleotide catabolic process GO:0009154 75 0.020
purine containing compound metabolic process GO:0072521 95 0.019
multi multicellular organism process GO:0044706 390 0.019
glycosyl compound catabolic process GO:1901658 79 0.019
actin filament based process GO:0030029 191 0.019
actomyosin structure organization GO:0031032 154 0.019
intracellular signal transduction GO:0035556 96 0.019
positive regulation of cellular catabolic process GO:0031331 35 0.019
macromolecular complex assembly GO:0065003 193 0.019
regulation of cell cycle process GO:0010564 145 0.019
purine ribonucleoside metabolic process GO:0046128 92 0.019
regulation of multi organism process GO:0043900 69 0.019
transcription from rna polymerase ii promoter GO:0006366 149 0.019
regulation of cell cycle GO:0051726 194 0.018
head development GO:0060322 1 0.018
sensory organ morphogenesis GO:0090596 2 0.018
vesicle mediated transport GO:0016192 852 0.018
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 5 0.018
cell proliferation GO:0008283 116 0.018
neuromuscular junction development GO:0007528 2 0.018
regulation of primary metabolic process GO:0080090 292 0.018
regulation of post embryonic development GO:0048580 260 0.018
regulation of nematode larval development GO:0061062 260 0.017
phagocytosis GO:0006909 115 0.017
ribonucleoside triphosphate metabolic process GO:0009199 87 0.017
axonogenesis GO:0007409 102 0.017
establishment of organelle localization GO:0051656 123 0.017
positive regulation of rna metabolic process GO:0051254 103 0.017
cell cell signaling GO:0007267 118 0.017
cell motility GO:0048870 313 0.017
negative regulation of response to stimulus GO:0048585 73 0.017
cell morphogenesis involved in differentiation GO:0000904 112 0.017
developmental maturation GO:0021700 26 0.016
purine ribonucleoside catabolic process GO:0046130 75 0.016
cellular biosynthetic process GO:0044249 315 0.016
multicellular organismal reproductive behavior GO:0033057 384 0.016
organ morphogenesis GO:0009887 67 0.016
membrane invagination GO:0010324 98 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.016
cellular response to dna damage stimulus GO:0006974 41 0.016
system process GO:0003008 136 0.015
regulation of molecular function GO:0065009 89 0.015
ribonucleoside monophosphate metabolic process GO:0009161 45 0.015
synaptic growth at neuromuscular junction GO:0051124 1 0.015
cell migration GO:0016477 306 0.015
meiotic spindle elongation GO:0051232 3 0.015
multi organism behavior GO:0051705 389 0.015
biosynthetic process GO:0009058 323 0.015
ribonucleotide metabolic process GO:0009259 99 0.015
ion transport GO:0006811 113 0.015
striated muscle myosin thick filament assembly GO:0071688 138 0.015
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.015
macromolecule biosynthetic process GO:0009059 250 0.014
phosphorus metabolic process GO:0006793 232 0.014
multi organism reproductive behavior GO:0044705 387 0.014
chromatin organization GO:0006325 32 0.014
negative regulation of signaling GO:0023057 61 0.014
membrane organization GO:0061024 135 0.014
actin cytoskeleton organization GO:0030036 184 0.014
negative regulation of cell cycle GO:0045786 53 0.014
organelle assembly GO:0070925 214 0.014
ribose phosphate metabolic process GO:0019693 99 0.014
purine nucleoside metabolic process GO:0042278 92 0.014
establishment of nucleus localization GO:0040023 55 0.014
multicellular organismal reproductive process GO:0048609 815 0.013
positive regulation of cellular protein catabolic process GO:1903364 3 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.013
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.013
cell morphogenesis GO:0000902 163 0.013
regulation of synapse assembly GO:0051963 2 0.013
histone h3 k27 demethylation GO:0071557 3 0.013
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 1 0.013
molting cycle GO:0042303 281 0.013
positive regulation of cell death GO:0010942 38 0.013
negative regulation of response to external stimulus GO:0032102 3 0.013
positive regulation of catabolic process GO:0009896 38 0.012
negative regulation of cell communication GO:0010648 61 0.012
pronuclear migration GO:0035046 51 0.012
g1 s transition of mitotic cell cycle GO:0000082 2 0.012
multicellular organism reproduction GO:0032504 819 0.012
meiotic cell cycle GO:0051321 335 0.012
histone modification GO:0016570 30 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.012
defense response GO:0006952 296 0.012
anterior posterior pattern specification GO:0009952 27 0.012
secretion GO:0046903 147 0.012
nucleoside triphosphate metabolic process GO:0009141 87 0.012
purine nucleoside catabolic process GO:0006152 75 0.012
homeostatic process GO:0042592 51 0.012
nucleoside monophosphate metabolic process GO:0009123 46 0.011
enzyme linked receptor protein signaling pathway GO:0007167 50 0.011
positive regulation of molecular function GO:0044093 61 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
oviposition GO:0018991 364 0.011
regulation of cell death GO:0010941 65 0.011
negative regulation of signal transduction GO:0009968 60 0.011
apoptotic cell clearance GO:0043277 111 0.011
nucleoside metabolic process GO:0009116 99 0.011
small molecule metabolic process GO:0044281 186 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.011
protein phosphorylation GO:0006468 85 0.011
ribonucleotide catabolic process GO:0009261 75 0.011
behavior GO:0007610 527 0.011
Mouse
regulation of intracellular signal transduction GO:1902531 77 0.011
mitotic sister chromatid segregation GO:0000070 38 0.010
regulation of cytoskeleton organization GO:0051493 41 0.010
positive regulation of protein metabolic process GO:0051247 45 0.010
positive regulation of biosynthetic process GO:0009891 109 0.010
nucleotide catabolic process GO:0009166 77 0.010
nuclear migration GO:0007097 54 0.010
organophosphate metabolic process GO:0019637 125 0.010
regulation of protein localization GO:0032880 50 0.010
chemotaxis GO:0006935 120 0.010

atx-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
central nervous system disease DOID:331 0 0.020
neurodegenerative disease DOID:1289 0 0.020
nervous system disease DOID:863 0 0.020
spinocerebellar degeneration DOID:2478 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
cancer DOID:162 0 0.020
organ system cancer DOID:0050686 0 0.020