Caenorhabditis elegans

0 known processes

gck-2 (CELE_ZC404.9)

Protein GCK-2

gck-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.832
sexual reproduction GO:0019953 546 0.707
embryo development GO:0009790 3052 0.581
programmed cell death GO:0012501 500 0.475
regulation of multicellular organismal process GO:0051239 726 0.454
post embryonic development GO:0009791 2152 0.428
multicellular organism reproduction GO:0032504 819 0.416
regulation of developmental process GO:0050793 684 0.399
receptor mediated endocytosis GO:0006898 715 0.372
protein metabolic process GO:0019538 422 0.339
apoptotic process GO:0006915 478 0.310
nervous system development GO:0007399 253 0.308
phosphate containing compound metabolic process GO:0006796 232 0.304
regulation of metabolic process GO:0019222 478 0.303
transport GO:0006810 1093 0.294
locomotion GO:0040011 1634 0.289
organic substance catabolic process GO:1901575 294 0.287
multicellular organismal reproductive process GO:0048609 815 0.273
body morphogenesis GO:0010171 620 0.270
regulation of vulval development GO:0040028 248 0.254
macromolecule catabolic process GO:0009057 202 0.253
cell division GO:0051301 262 0.248
cell part morphogenesis GO:0032990 152 0.245
single organism catabolic process GO:0044712 129 0.233
catabolic process GO:0009056 318 0.231
vesicle mediated transport GO:0016192 852 0.228
embryonic body morphogenesis GO:0010172 49 0.226
determination of adult lifespan GO:0008340 812 0.225
establishment of localization GO:0051234 1171 0.225
post embryonic organ development GO:0048569 336 0.222
cellular catabolic process GO:0044248 199 0.219
organelle fission GO:0048285 363 0.216
negative regulation of developmental process GO:0051093 227 0.202
localization of cell GO:0051674 313 0.198
multi organism reproductive process GO:0044703 867 0.196
vulval development GO:0040025 333 0.188
multicellular organismal aging GO:0010259 812 0.184
phosphorus metabolic process GO:0006793 232 0.177
neuron differentiation GO:0030182 217 0.173
aging GO:0007568 812 0.165
endocytosis GO:0006897 819 0.160
regulation of macromolecule metabolic process GO:0060255 421 0.157
negative regulation of multicellular organismal process GO:0051241 236 0.155
oviposition GO:0018991 364 0.154
gene expression GO:0010467 412 0.154
growth GO:0040007 562 0.152
mitotic sister chromatid segregation GO:0000070 38 0.147
single organism signaling GO:0044700 401 0.146
cuticle development GO:0042335 100 0.144
regulation of signal transduction GO:0009966 135 0.143
cell projection organization GO:0030030 231 0.143
female gamete generation GO:0007292 254 0.139
reproductive structure development GO:0048608 850 0.138
regulation of nitrogen compound metabolic process GO:0051171 222 0.136
death GO:0016265 547 0.135
cell development GO:0048468 696 0.134
actin filament based process GO:0030029 191 0.133
neuron projection guidance GO:0097485 82 0.129
generation of neurons GO:0048699 235 0.128
negative regulation of nematode larval development GO:0061064 208 0.123
regulation of signaling GO:0023051 172 0.123
cellular protein modification process GO:0006464 207 0.121
cell migration GO:0016477 306 0.121
cell projection morphogenesis GO:0048858 148 0.118
neurogenesis GO:0022008 236 0.118
biosynthetic process GO:0009058 323 0.117
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.116
sex differentiation GO:0007548 909 0.115
positive regulation of cellular process GO:0048522 332 0.114
organ development GO:0048513 1102 0.112
response to chemical GO:0042221 356 0.111
nucleobase containing compound metabolic process GO:0006139 406 0.111
macromolecule biosynthetic process GO:0009059 250 0.109
cellular biosynthetic process GO:0044249 315 0.108
cell fate commitment GO:0045165 139 0.107
inductive cell migration GO:0040039 145 0.104
cell death GO:0008219 547 0.100
multicellular organismal reproductive behavior GO:0033057 384 0.100
developmental process involved in reproduction GO:0003006 1165 0.100
meiotic cell cycle process GO:1903046 170 0.098
regulation of biological quality GO:0065008 741 0.098
developmental growth GO:0048589 412 0.097
signal transduction GO:0007165 317 0.095
single organism reproductive process GO:0044702 1196 0.093
organic substance biosynthetic process GO:1901576 323 0.092
regulation of cell communication GO:0010646 176 0.091
organic cyclic compound catabolic process GO:1901361 119 0.089
collagen and cuticulin based cuticle development GO:0040002 99 0.087
oogenesis GO:0048477 229 0.086
membrane organization GO:0061024 135 0.086
regulation of mitosis GO:0007088 18 0.086
ras protein signal transduction GO:0007265 31 0.085
regulation of developmental growth GO:0048638 389 0.085
regulation of cellular metabolic process GO:0031323 305 0.080
cellular component movement GO:0006928 388 0.079
multi multicellular organism process GO:0044706 390 0.078
regulation of localization GO:0032879 194 0.077
organonitrogen compound metabolic process GO:1901564 151 0.077
regulation of primary metabolic process GO:0080090 292 0.077
germ cell development GO:0007281 351 0.076
positive regulation of growth GO:0045927 369 0.075
regulation of sister chromatid segregation GO:0033045 16 0.074
multi organism reproductive behavior GO:0044705 387 0.074
single organism localization GO:1902578 518 0.073
response to external stimulus GO:0009605 289 0.073
gamete generation GO:0007276 461 0.073
regulation of growth GO:0040008 409 0.072
cell cycle GO:0007049 526 0.072
heterocycle catabolic process GO:0046700 119 0.072
signaling GO:0023052 401 0.071
meiotic cell cycle GO:0051321 335 0.071
positive regulation of developmental growth GO:0048639 354 0.070
behavior GO:0007610 527 0.070
gonad development GO:0008406 840 0.070
macromolecule localization GO:0033036 771 0.069
lipid localization GO:0010876 573 0.068
positive regulation of multicellular organismal process GO:0051240 417 0.068
regulation of response to stimulus GO:0048583 243 0.067
lipid storage GO:0019915 565 0.067
cellular macromolecule biosynthetic process GO:0034645 247 0.067
male sex differentiation GO:0046661 86 0.067
neuron development GO:0048666 199 0.067
negative regulation of biological process GO:0048519 567 0.066
regulation of cell migration GO:0030334 55 0.066
cellular component morphogenesis GO:0032989 318 0.066
nucleus organization GO:0006997 38 0.065
negative regulation of vulval development GO:0040027 206 0.065
nucleic acid metabolic process GO:0090304 299 0.065
regulation of nematode larval development GO:0061062 260 0.064
actin cytoskeleton organization GO:0030036 184 0.064
maintenance of location GO:0051235 580 0.063
cell morphogenesis GO:0000902 163 0.063
multicellular organism growth GO:0035264 385 0.063
neuron projection development GO:0031175 187 0.063
transcription dna templated GO:0006351 168 0.063
regulation of post embryonic development GO:0048580 260 0.062
cell motility GO:0048870 313 0.060
cytoskeleton organization GO:0007010 339 0.060
hermaphrodite genitalia development GO:0040035 734 0.060
cell surface receptor signaling pathway GO:0007166 149 0.059
regulation of anatomical structure morphogenesis GO:0022603 51 0.059
regulation of locomotion GO:0040012 161 0.059
cellular protein metabolic process GO:0044267 279 0.059
cellular nitrogen compound catabolic process GO:0044270 119 0.058
microtubule based process GO:0007017 182 0.058
aromatic compound catabolic process GO:0019439 116 0.057
macromolecular complex subunit organization GO:0043933 320 0.057
nucleobase containing compound catabolic process GO:0034655 114 0.057
genitalia development GO:0048806 741 0.055
phosphorylation GO:0016310 116 0.054
multi organism behavior GO:0051705 389 0.053
phagocytosis GO:0006909 115 0.051
small molecule metabolic process GO:0044281 186 0.051
axonogenesis GO:0007409 102 0.050
cell cycle process GO:0022402 482 0.050
single organism transport GO:0044765 447 0.048
reproductive system development GO:0061458 850 0.047
negative regulation of post embryonic development GO:0048581 208 0.047
protein phosphorylation GO:0006468 85 0.046
development of primary sexual characteristics GO:0045137 840 0.046
anatomical structure formation involved in morphogenesis GO:0048646 250 0.046
regulation of multicellular organism growth GO:0040014 373 0.046
fibroblast growth factor receptor signaling pathway GO:0008543 5 0.046
negative regulation of cellular process GO:0048523 239 0.046
chromosome segregation GO:0007059 180 0.045
nucleoside metabolic process GO:0009116 99 0.045
response to fibroblast growth factor GO:0071774 5 0.044
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.044
axon guidance GO:0007411 82 0.044
dorsal ventral axon guidance GO:0033563 19 0.044
cytoskeleton dependent cytokinesis GO:0061640 35 0.044
protein modification process GO:0036211 207 0.043
regulation of chromosome segregation GO:0051983 20 0.043
neuron projection morphogenesis GO:0048812 114 0.043
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.042
positive regulation of rna metabolic process GO:0051254 103 0.042
digestive tract morphogenesis GO:0048546 76 0.042
glycoprotein metabolic process GO:0009100 29 0.042
organophosphate metabolic process GO:0019637 125 0.042
organelle organization GO:0006996 783 0.042
small gtpase mediated signal transduction GO:0007264 32 0.041
developmental induction GO:0031128 1 0.040
mitotic cell cycle process GO:1903047 194 0.038
carbohydrate derivative metabolic process GO:1901135 141 0.038
tube formation GO:0035148 2 0.038
cellular component biogenesis GO:0044085 297 0.038
embryonic morphogenesis GO:0048598 152 0.037
organelle localization GO:0051640 127 0.037
regulation of stem cell differentiation GO:2000736 1 0.037
positive regulation of developmental process GO:0051094 408 0.037
rna biosynthetic process GO:0032774 169 0.037
nucleoside phosphate catabolic process GO:1901292 77 0.037
regulation of phosphate metabolic process GO:0019220 81 0.036
positive regulation of cellular metabolic process GO:0031325 178 0.036
negative regulation of metabolic process GO:0009892 240 0.036
cellular macromolecule catabolic process GO:0044265 73 0.035
regulation of organ morphogenesis GO:2000027 4 0.035
regulation of phosphorus metabolic process GO:0051174 81 0.035
specification of axis polarity GO:0065001 13 0.034
regulation of nucleic acid templated transcription GO:1903506 165 0.034
positive regulation of multicellular organism growth GO:0040018 352 0.034
axon development GO:0061564 163 0.034
protein catabolic process GO:0030163 162 0.034
cell morphogenesis involved in differentiation GO:0000904 112 0.033
positive regulation of metabolic process GO:0009893 187 0.033
nucleobase containing compound biosynthetic process GO:0034654 184 0.033
organic cyclic compound biosynthetic process GO:1901362 195 0.033
single fertilization GO:0007338 61 0.032
secretion GO:0046903 147 0.032
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.031
regulation of multicellular organismal development GO:2000026 317 0.031
heterocycle biosynthetic process GO:0018130 187 0.031
meiotic nuclear division GO:0007126 300 0.031
directional locomotion GO:0033058 14 0.031
regulation of biosynthetic process GO:0009889 189 0.030
mating GO:0007618 34 0.030
glycosyl compound metabolic process GO:1901657 100 0.030
ribonucleotide metabolic process GO:0009259 99 0.030
purine nucleoside metabolic process GO:0042278 92 0.029
aromatic compound biosynthetic process GO:0019438 192 0.029
negative regulation of neurogenesis GO:0050768 4 0.029
tube morphogenesis GO:0035239 79 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.028
regulation of transcription dna templated GO:0006355 164 0.028
purine nucleoside catabolic process GO:0006152 75 0.028
sister chromatid segregation GO:0000819 46 0.027
posttranscriptional gene silencing by rna GO:0035194 143 0.027
regulation of cellular biosynthetic process GO:0031326 189 0.027
oocyte differentiation GO:0009994 45 0.027
regulation of synapse assembly GO:0051963 2 0.027
purine nucleotide catabolic process GO:0006195 75 0.027
single organism organelle organization GO:1902589 501 0.026
gastrulation GO:0007369 58 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.026
cellular macromolecular complex assembly GO:0034622 184 0.026
reproductive behavior GO:0019098 387 0.026
nucleoside triphosphate catabolic process GO:0009143 72 0.026
nucleoside triphosphate metabolic process GO:0009141 87 0.026
apical junction assembly GO:0043297 1 0.026
regulation of cell differentiation GO:0045595 81 0.026
nucleoside phosphate metabolic process GO:0006753 108 0.025
carbohydrate derivative catabolic process GO:1901136 82 0.025
positive regulation of ras gtpase activity GO:0032320 19 0.024
protein complex subunit organization GO:0071822 280 0.024
ribose phosphate metabolic process GO:0019693 99 0.024
regulation of organelle organization GO:0033043 164 0.023
purine containing compound metabolic process GO:0072521 95 0.023
organonitrogen compound catabolic process GO:1901565 90 0.023
negative regulation of macromolecule metabolic process GO:0010605 229 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.023
regulation of rna biosynthetic process GO:2001141 165 0.022
regulation of chromosome organization GO:0033044 20 0.022
organophosphate catabolic process GO:0046434 81 0.022
gene silencing by rna GO:0031047 143 0.022
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 2 0.022
regulation of intracellular signal transduction GO:1902531 77 0.021
defense response to bacterium GO:0042742 86 0.021
head development GO:0060322 1 0.021
nucleobase containing small molecule metabolic process GO:0055086 115 0.020
nucleoside catabolic process GO:0009164 78 0.020
regulation of gene expression epigenetic GO:0040029 163 0.020
positive regulation of cell communication GO:0010647 69 0.020
gtp catabolic process GO:0006184 46 0.020
metaphase anaphase transition of cell cycle GO:0044784 15 0.020
purine nucleoside triphosphate catabolic process GO:0009146 72 0.020
glycosyl compound catabolic process GO:1901658 79 0.020
cellular component assembly GO:0022607 293 0.020
posttranscriptional gene silencing GO:0016441 143 0.019
positive regulation of stem cell differentiation GO:2000738 1 0.019
protein localization GO:0008104 205 0.019
regulation of transport GO:0051049 91 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.019
regulation of cell development GO:0060284 49 0.019
digestive tract development GO:0048565 122 0.019
regulation of mitotic sister chromatid segregation GO:0033047 16 0.019
regulation of gene expression GO:0010468 366 0.018
rna metabolic process GO:0016070 228 0.018
neuromuscular junction development GO:0007528 2 0.018
regulation of cellular component organization GO:0051128 248 0.018
polarity specification of proximal distal axis GO:0010085 6 0.018
organic acid metabolic process GO:0006082 47 0.018
cellular localization GO:0051641 360 0.018
regulation of cell morphogenesis GO:0022604 40 0.018
mapk cascade GO:0000165 31 0.018
negative regulation of cellular metabolic process GO:0031324 95 0.017
regulation of molecular function GO:0065009 89 0.017
regulation of multi organism process GO:0043900 69 0.017
muscle cell differentiation GO:0042692 171 0.017
cell cell signaling GO:0007267 118 0.017
regulation of reproductive process GO:2000241 66 0.017
synaptic transmission GO:0007268 106 0.017
regulation of cellular component movement GO:0051270 62 0.017
guanosine containing compound catabolic process GO:1901069 48 0.017
apoptotic cell clearance GO:0043277 111 0.017
regulation of behavior GO:0050795 97 0.017
establishment of organelle localization GO:0051656 123 0.017
oxoacid metabolic process GO:0043436 47 0.017
engulfment of apoptotic cell GO:0043652 94 0.016
regulation of ras protein signal transduction GO:0046578 41 0.016
skeletal muscle organ development GO:0060538 3 0.016
purine ribonucleoside catabolic process GO:0046130 75 0.016
intracellular signal transduction GO:0035556 96 0.016
negative regulation of cellular component organization GO:0051129 33 0.016
taxis GO:0042330 128 0.016
organelle assembly GO:0070925 214 0.016
epithelial tube morphogenesis GO:0060562 1 0.015
establishment or maintenance of cell polarity GO:0007163 63 0.015
regulation of attachment of spindle microtubules to kinetochore GO:0051988 2 0.015
macromolecule modification GO:0043412 218 0.015
organ morphogenesis GO:0009887 67 0.015
gtp metabolic process GO:0046039 46 0.015
regulation of cell motility GO:2000145 57 0.015
ribonucleoside triphosphate metabolic process GO:0009199 87 0.014
regulation of cell fate commitment GO:0010453 22 0.014
response to wounding GO:0009611 4 0.014
mitotic sister chromatid separation GO:0051306 13 0.014
canonical wnt signaling pathway GO:0060070 3 0.014
dendrite development GO:0016358 42 0.014
purine ribonucleotide catabolic process GO:0009154 75 0.014
ribonucleoside triphosphate catabolic process GO:0009203 72 0.014
nucleotide metabolic process GO:0009117 108 0.014
dna metabolic process GO:0006259 74 0.014
protein complex assembly GO:0006461 186 0.014
cellular protein catabolic process GO:0044257 37 0.014
positive regulation of response to stimulus GO:0048584 55 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.014
ubiquitin dependent protein catabolic process GO:0006511 32 0.014
nucleic acid templated transcription GO:0097659 169 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.013
regulation of microtubule cytoskeleton organization GO:0070507 21 0.013
membrane invagination GO:0010324 98 0.013
response to bacterium GO:0009617 86 0.013
regulation of cytoskeleton organization GO:0051493 41 0.013
single organism biosynthetic process GO:0044711 91 0.013
positive regulation of cellular catabolic process GO:0031331 35 0.013
positive regulation of neurogenesis GO:0050769 4 0.013
mitotic nuclear division GO:0007067 89 0.013
phagocytosis engulfment GO:0006911 98 0.013
cellular response to organic substance GO:0071310 119 0.013
myosin filament organization GO:0031033 138 0.013
myofibril assembly GO:0030239 154 0.013
regulation of cell cycle GO:0051726 194 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
response to abiotic stimulus GO:0009628 152 0.013
rna interference GO:0016246 137 0.013
ribonucleoside metabolic process GO:0009119 98 0.013
tissue development GO:0009888 112 0.013
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 10 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.013
rho protein signal transduction GO:0007266 2 0.012
cellular response to stress GO:0033554 162 0.012
spindle localization GO:0051653 51 0.012
regulation of axonogenesis GO:0050770 24 0.012
meiotic cytokinesis GO:0033206 15 0.012
cellular response to chemical stimulus GO:0070887 129 0.012
tissue morphogenesis GO:0048729 65 0.012
cellular protein complex assembly GO:0043623 178 0.012
rna localization GO:0006403 3 0.012
regulation of nervous system development GO:0051960 41 0.012
organic substance transport GO:0071702 113 0.012
establishment of localization in cell GO:0051649 318 0.012
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
posttranscriptional regulation of gene expression GO:0010608 166 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.011
regulation of protein metabolic process GO:0051246 81 0.011
striated muscle cell development GO:0055002 157 0.011
digestive system development GO:0055123 122 0.011
regulation of nuclear division GO:0051783 115 0.011
regulation of cell division GO:0051302 142 0.011
cell junction organization GO:0034330 18 0.011
amine metabolic process GO:0009308 15 0.011
regulation of embryonic development GO:0045995 16 0.011
regulation of cell cell adhesion GO:0022407 1 0.011
polar body extrusion after meiotic divisions GO:0040038 14 0.011
purine ribonucleotide metabolic process GO:0009150 95 0.010
cellular ketone metabolic process GO:0042180 14 0.010
purine nucleoside triphosphate metabolic process GO:0009144 87 0.010
protein modification by small protein conjugation or removal GO:0070647 40 0.010
mitotic spindle organization GO:0007052 81 0.010
purine nucleotide metabolic process GO:0006163 95 0.010
oocyte development GO:0048599 44 0.010
muscle structure development GO:0061061 191 0.010
regulation of catalytic activity GO:0050790 78 0.010
actin cytoskeleton reorganization GO:0031532 4 0.010
cellular amine metabolic process GO:0044106 15 0.010

gck-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
integumentary system disease DOID:16 0 0.081
skin disease DOID:37 0 0.081
lipodystrophy DOID:811 0 0.081
familial partial lipodystrophy DOID:0050440 0 0.081
disease of anatomical entity DOID:7 0 0.081
musculoskeletal system disease DOID:17 0 0.016
cardiomyopathy DOID:0050700 0 0.016
heart disease DOID:114 0 0.016
muscle tissue disease DOID:66 0 0.016
cardiovascular system disease DOID:1287 0 0.016
muscular disease DOID:0080000 0 0.016
myopathy DOID:423 0 0.016
nervous system disease DOID:863 0 0.011