Caenorhabditis elegans

21 known processes

his-25 (CELE_ZK131.2)

Protein HIS-25

his-25 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
genitalia development GO:0048806 741 0.322
Worm
reproductive structure development GO:0048608 850 0.311
Worm
gonad development GO:0008406 840 0.301
Worm
single organism reproductive process GO:0044702 1196 0.273
Yeast Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.268
sex differentiation GO:0007548 909 0.258
Worm
hermaphrodite genitalia development GO:0040035 734 0.254
Worm
embryo development GO:0009790 3052 0.247
developmental process involved in reproduction GO:0003006 1165 0.246
Yeast Worm
reproductive system development GO:0061458 850 0.228
Worm
organ development GO:0048513 1102 0.226
Worm
development of primary sexual characteristics GO:0045137 840 0.225
Worm
post embryonic development GO:0009791 2152 0.201
locomotion GO:0040011 1634 0.174
Worm
defense response GO:0006952 296 0.141
organelle organization GO:0006996 783 0.139
Yeast
establishment of localization GO:0051234 1171 0.139
receptor mediated endocytosis GO:0006898 715 0.128
multi organism reproductive process GO:0044703 867 0.128
Yeast
transport GO:0006810 1093 0.124
vesicle mediated transport GO:0016192 852 0.117
multicellular organism reproduction GO:0032504 819 0.111
multicellular organismal reproductive process GO:0048609 815 0.109
body morphogenesis GO:0010171 620 0.109
multicellular organismal aging GO:0010259 812 0.107
Worm
digestive tract development GO:0048565 122 0.106
endocytosis GO:0006897 819 0.099
multicellular organismal reproductive behavior GO:0033057 384 0.097
determination of adult lifespan GO:0008340 812 0.096
Worm
macromolecule localization GO:0033036 771 0.094
digestive system development GO:0055123 122 0.090
oviposition GO:0018991 364 0.089
regulation of biological quality GO:0065008 741 0.084
aging GO:0007568 812 0.079
Worm
lipid localization GO:0010876 573 0.073
cell development GO:0048468 696 0.073
behavior GO:0007610 527 0.072
maintenance of location GO:0051235 580 0.071
multi organism reproductive behavior GO:0044705 387 0.070
pharynx development GO:0060465 51 0.069
transcription dna templated GO:0006351 168 0.068
Yeast
negative regulation of biological process GO:0048519 567 0.068
Yeast
cell death GO:0008219 547 0.068
multi organism behavior GO:0051705 389 0.067
lipid storage GO:0019915 565 0.067
single organism organelle organization GO:1902589 501 0.065
Yeast
gene expression GO:0010467 412 0.064
Yeast
regulation of multicellular organismal process GO:0051239 726 0.064
regulation of macromolecule metabolic process GO:0060255 421 0.064
Yeast
negative regulation of gene expression epigenetic GO:0045814 2 0.063
single organism localization GO:1902578 518 0.063
multi multicellular organism process GO:0044706 390 0.063
death GO:0016265 547 0.062
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.062
reproductive behavior GO:0019098 387 0.061
macromolecular complex subunit organization GO:0043933 320 0.057
apoptotic process GO:0006915 478 0.056
regulation of gene expression GO:0010468 366 0.055
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.055
cellular macromolecule biosynthetic process GO:0034645 247 0.054
Yeast
programmed cell death GO:0012501 500 0.053
regulation of cellular metabolic process GO:0031323 305 0.053
Yeast
positive regulation of growth GO:0045927 369 0.053
regulation of metabolic process GO:0019222 478 0.052
Yeast
regulation of developmental process GO:0050793 684 0.052
nucleobase containing compound metabolic process GO:0006139 406 0.052
Yeast
regulation of primary metabolic process GO:0080090 292 0.051
Yeast
meiotic cell cycle process GO:1903046 170 0.051
Yeast
single organism transport GO:0044765 447 0.051
positive regulation of multicellular organismal process GO:0051240 417 0.051
sexual reproduction GO:0019953 546 0.050
Yeast
regulation of multicellular organism growth GO:0040014 373 0.049
positive regulation of developmental process GO:0051094 408 0.049
regulation of developmental growth GO:0048638 389 0.049
rna metabolic process GO:0016070 228 0.048
Yeast
growth GO:0040007 562 0.048
cell cycle process GO:0022402 482 0.048
Yeast
organic cyclic compound biosynthetic process GO:1901362 195 0.048
Yeast
anatomical structure formation involved in morphogenesis GO:0048646 250 0.048
Yeast
developmental growth GO:0048589 412 0.047
cellular biosynthetic process GO:0044249 315 0.047
Yeast
gamete generation GO:0007276 461 0.047
regulation of growth GO:0040008 409 0.047
multicellular organism growth GO:0035264 385 0.046
cellular localization GO:0051641 360 0.046
regulation of gene expression epigenetic GO:0040029 163 0.046
cytoskeleton organization GO:0007010 339 0.046
regulation of rna biosynthetic process GO:2001141 165 0.045
establishment of localization in cell GO:0051649 318 0.045
nucleic acid templated transcription GO:0097659 169 0.044
Yeast
actin filament based process GO:0030029 191 0.044
meiotic cell cycle GO:0051321 335 0.044
Yeast
positive regulation of developmental growth GO:0048639 354 0.044
tube development GO:0035295 126 0.043
nucleic acid metabolic process GO:0090304 299 0.043
Yeast
positive regulation of multicellular organism growth GO:0040018 352 0.043
regulation of nucleic acid templated transcription GO:1903506 165 0.043
negative regulation of macromolecule metabolic process GO:0010605 229 0.043
Yeast
cell cycle GO:0007049 526 0.042
Yeast
molting cycle GO:0042303 281 0.042
transcription from rna polymerase ii promoter GO:0006366 149 0.042
protein metabolic process GO:0019538 422 0.042
Yeast
organelle assembly GO:0070925 214 0.041
aromatic compound biosynthetic process GO:0019438 192 0.040
Yeast
regulation of cellular biosynthetic process GO:0031326 189 0.040
cellular component biogenesis GO:0044085 297 0.040
regulation of transcription dna templated GO:0006355 164 0.040
protein complex subunit organization GO:0071822 280 0.040
actin cytoskeleton organization GO:0030036 184 0.039
organic substance biosynthetic process GO:1901576 323 0.038
Yeast
biosynthetic process GO:0009058 323 0.038
Yeast
negative regulation of gene expression GO:0010629 217 0.038
Yeast
cellular component morphogenesis GO:0032989 318 0.038
negative regulation of metabolic process GO:0009892 240 0.037
Yeast
cellular component assembly GO:0022607 293 0.037
rna biosynthetic process GO:0032774 169 0.037
Yeast
cellular protein complex assembly GO:0043623 178 0.037
cellular component assembly involved in morphogenesis GO:0010927 183 0.037
gene silencing GO:0016458 143 0.037
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.037
heterocycle biosynthetic process GO:0018130 187 0.036
Yeast
organelle fission GO:0048285 363 0.036
Yeast
regulation of macromolecule biosynthetic process GO:0010556 189 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.036
cellular macromolecular complex assembly GO:0034622 184 0.036
macromolecule biosynthetic process GO:0009059 250 0.035
Yeast
nucleobase containing compound biosynthetic process GO:0034654 184 0.035
Yeast
regulation of rna metabolic process GO:0051252 173 0.035
protein complex biogenesis GO:0070271 186 0.035
positive regulation of cellular process GO:0048522 332 0.035
vulval development GO:0040025 333 0.035
signaling GO:0023052 401 0.035
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.034
myofibril assembly GO:0030239 154 0.033
germ cell development GO:0007281 351 0.033
actomyosin structure organization GO:0031032 154 0.032
negative regulation of cellular process GO:0048523 239 0.032
Yeast
macromolecular complex assembly GO:0065003 193 0.032
single organism signaling GO:0044700 401 0.031
response to chemical GO:0042221 356 0.031
cellular nitrogen compound biosynthetic process GO:0044271 192 0.031
Yeast
regulation of multicellular organismal development GO:2000026 317 0.031
innate immune response GO:0045087 190 0.031
immune response GO:0006955 192 0.031
protein modification process GO:0036211 207 0.031
striated muscle cell development GO:0055002 157 0.030
muscle cell development GO:0055001 158 0.030
regulation of nitrogen compound metabolic process GO:0051171 222 0.030
nucleus organization GO:0006997 38 0.030
cellular protein metabolic process GO:0044267 279 0.029
Yeast
secretion by cell GO:0032940 138 0.029
meiotic nuclear division GO:0007126 300 0.029
protein complex assembly GO:0006461 186 0.029
striated muscle myosin thick filament assembly GO:0071688 138 0.029
striated muscle cell differentiation GO:0051146 158 0.029
cellular component movement GO:0006928 388 0.028
post embryonic organ development GO:0048569 336 0.028
secretion GO:0046903 147 0.028
regulation of biosynthetic process GO:0009889 189 0.028
muscle structure development GO:0061061 191 0.028
myosin filament assembly GO:0031034 138 0.028
localization of cell GO:0051674 313 0.027
macromolecule modification GO:0043412 218 0.027
myosin filament organization GO:0031033 138 0.026
muscle cell differentiation GO:0042692 171 0.026
response to wounding GO:0009611 4 0.026
catabolic process GO:0009056 318 0.025
Yeast
small molecule metabolic process GO:0044281 186 0.025
cellular protein modification process GO:0006464 207 0.025
positive regulation of cellular biosynthetic process GO:0031328 109 0.025
regulation of nematode larval development GO:0061062 260 0.025
head development GO:0060322 1 0.024
cell division GO:0051301 262 0.024
Yeast
regulation of vulval development GO:0040028 248 0.024
cell migration GO:0016477 306 0.024
negative regulation of multicellular organismal process GO:0051241 236 0.024
regulation of post embryonic development GO:0048580 260 0.023
signal transduction GO:0007165 317 0.023
regulation of cellular component organization GO:0051128 248 0.023
Yeast
negative regulation of nucleic acid templated transcription GO:1903507 53 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.023
cell motility GO:0048870 313 0.023
regulation of organelle organization GO:0033043 164 0.022
Yeast
female gamete generation GO:0007292 254 0.022
organic substance catabolic process GO:1901575 294 0.022
Yeast
negative regulation of cellular metabolic process GO:0031324 95 0.022
Yeast
oogenesis GO:0048477 229 0.021
response to external stimulus GO:0009605 289 0.021
cellular response to stress GO:0033554 162 0.021
Yeast
chromosome organization GO:0051276 104 0.021
Yeast
negative regulation of developmental process GO:0051093 227 0.021
chromatin assembly or disassembly GO:0006333 1 0.021
positive regulation of cellular metabolic process GO:0031325 178 0.021
negative regulation of transcription dna templated GO:0045892 53 0.020
positive regulation of metabolic process GO:0009893 187 0.020
sensory organ morphogenesis GO:0090596 2 0.020
negative regulation of post embryonic development GO:0048581 208 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.020
negative regulation of nematode larval development GO:0061064 208 0.020
regulation of response to stimulus GO:0048583 243 0.020
regulation of cell communication GO:0010646 176 0.020
macromolecule catabolic process GO:0009057 202 0.019
Yeast
regulation of cellular ketone metabolic process GO:0010565 3 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
negative regulation of biosynthetic process GO:0009890 65 0.019
regulation of localization GO:0032879 194 0.018
negative regulation of vulval development GO:0040027 206 0.018
protein catabolic process GO:0030163 162 0.018
Yeast
dna repair GO:0006281 23 0.018
Yeast
regulation of cytoplasmic transport GO:1903649 3 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.018
regulation of nuclear division GO:0051783 115 0.018
Yeast
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.018
cellular ketone metabolic process GO:0042180 14 0.018
phosphorus metabolic process GO:0006793 232 0.017
negative regulation of rna biosynthetic process GO:1902679 53 0.017
regulation of meiotic cell cycle GO:0051445 136 0.017
gene silencing by rna GO:0031047 143 0.017
inductive cell migration GO:0040039 145 0.017
protein localization GO:0008104 205 0.017
nervous system development GO:0007399 253 0.017
male sex differentiation GO:0046661 86 0.017
posttranscriptional gene silencing GO:0016441 143 0.017
organic acid metabolic process GO:0006082 47 0.017
posttranscriptional gene silencing by rna GO:0035194 143 0.017
response to topologically incorrect protein GO:0035966 82 0.016
dna metabolic process GO:0006259 74 0.016
Yeast
positive regulation of nucleic acid templated transcription GO:1903508 102 0.016
regulation of cell division GO:0051302 142 0.016
Yeast
meiotic chromosome segregation GO:0045132 139 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
carboxylic acid metabolic process GO:0019752 34 0.016
regulation of signaling GO:0023051 172 0.016
negative regulation of cellular biosynthetic process GO:0031327 65 0.016
positive regulation of rna metabolic process GO:0051254 103 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.016
neuron projection development GO:0031175 187 0.016
regulation of cell cycle GO:0051726 194 0.016
Yeast
phagocytosis GO:0006909 115 0.016
neuron development GO:0048666 199 0.015
cell projection organization GO:0030030 231 0.015
chromosome segregation GO:0007059 180 0.015
Yeast
rna interference GO:0016246 137 0.015
positive regulation of rna biosynthetic process GO:1902680 102 0.015
positive regulation of macromolecule metabolic process GO:0010604 149 0.015
regulation of nucleocytoplasmic transport GO:0046822 3 0.015
cell type specific apoptotic process GO:0097285 4 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
apoptotic cell clearance GO:0043277 111 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.015
positive regulation of gene expression GO:0010628 112 0.014
microtubule based process GO:0007017 182 0.014
neuromuscular junction development GO:0007528 2 0.014
regulation of meiosis GO:0040020 94 0.014
cuticle development GO:0042335 100 0.014
negative regulation of rna metabolic process GO:0051253 53 0.014
generation of neurons GO:0048699 235 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.014
collagen and cuticulin based cuticle development GO:0040002 99 0.014
organic substance transport GO:0071702 113 0.014
membrane organization GO:0061024 135 0.014
cell proliferation GO:0008283 116 0.014
positive regulation of neurogenesis GO:0050769 4 0.014
positive regulation of biosynthetic process GO:0009891 109 0.014
oxoacid metabolic process GO:0043436 47 0.014
positive regulation of transcription dna templated GO:0045893 102 0.014
cellular catabolic process GO:0044248 199 0.013
Yeast
phagocytosis engulfment GO:0006911 98 0.013
neuron differentiation GO:0030182 217 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
adult behavior GO:0030534 3 0.013
regulation of cell cycle process GO:0010564 145 0.013
Yeast
system process GO:0003008 136 0.013
lipid metabolic process GO:0006629 77 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
engulfment of apoptotic cell GO:0043652 94 0.013
cell substrate adhesion GO:0031589 1 0.013
cell cell signaling GO:0007267 118 0.013
regulation of cell proliferation GO:0042127 105 0.013
chromatin organization GO:0006325 32 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.013
axon development GO:0061564 163 0.012
protein oligomerization GO:0051259 4 0.012
response to organic substance GO:0010033 131 0.012
ribosome biogenesis GO:0042254 4 0.012
histone modification GO:0016570 30 0.012
membrane invagination GO:0010324 98 0.012
single organism catabolic process GO:0044712 129 0.012
Yeast
male anatomical structure morphogenesis GO:0090598 78 0.012
regulation of signal transduction GO:0009966 135 0.012
covalent chromatin modification GO:0016569 30 0.012
amine metabolic process GO:0009308 15 0.012
feeding behavior GO:0007631 70 0.012
response to abiotic stimulus GO:0009628 152 0.012
defense response to gram negative bacterium GO:0050829 64 0.012
cellular amine metabolic process GO:0044106 15 0.012
ion transport GO:0006811 113 0.012
cellular response to dna damage stimulus GO:0006974 41 0.012
Yeast
hormone transport GO:0009914 2 0.011
neurogenesis GO:0022008 236 0.011
response to biotic stimulus GO:0009607 101 0.011
cellular response to topologically incorrect protein GO:0035967 76 0.011
regulation of lipid metabolic process GO:0019216 4 0.011
aromatic compound catabolic process GO:0019439 116 0.011
regulation of protein targeting GO:1903533 3 0.011
organophosphate metabolic process GO:0019637 125 0.011
regulation of behavior GO:0050795 97 0.011
pharyngeal pumping GO:0043050 58 0.011
regulation of response to wounding GO:1903034 1 0.011
nematode male tail tip morphogenesis GO:0045138 77 0.011
response to acid chemical GO:0001101 4 0.011
eating behavior GO:0042755 59 0.011
response to other organism GO:0051707 101 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
chromatin modification GO:0016568 32 0.011
response to bacterium GO:0009617 86 0.011
peptidyl tyrosine phosphorylation GO:0018108 2 0.011
regulation of hormone secretion GO:0046883 2 0.011
organelle localization GO:0051640 127 0.011
cell morphogenesis GO:0000902 163 0.011
organic cyclic compound catabolic process GO:1901361 119 0.011
ribonucleotide metabolic process GO:0009259 99 0.010
carbohydrate derivative metabolic process GO:1901135 141 0.010
response to external biotic stimulus GO:0043207 101 0.010
establishment of organelle localization GO:0051656 123 0.010
cellular response to organic substance GO:0071310 119 0.010
cell part morphogenesis GO:0032990 152 0.010
cellular response to chemical stimulus GO:0070887 129 0.010
nucleobase containing compound catabolic process GO:0034655 114 0.010
regeneration GO:0031099 4 0.010
taxis GO:0042330 128 0.010
cell morphogenesis involved in differentiation GO:0000904 112 0.010

his-25 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.011