Saccharomyces cerevisiae

110 known processes

CKS1 (YBR135W)

Cks1p

CKS1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 19 0.986
regulation of transferase activity GO:0051338 83 0.941
regulation of protein kinase activity GO:0045859 67 0.924
regulation of protein phosphorylation GO:0001932 75 0.915
regulation of kinase activity GO:0043549 71 0.875
cell cycle phase transition GO:0044770 144 0.808
regulation of protein serine threonine kinase activity GO:0071900 41 0.797
regulation of catalytic activity GO:0050790 307 0.774
regulation of molecular function GO:0065009 320 0.758
cell cycle g2 m phase transition GO:0044839 39 0.752
mitotic cell cycle phase transition GO:0044772 141 0.737
cell cycle g1 s phase transition GO:0044843 64 0.721
g1 s transition of mitotic cell cycle GO:0000082 64 0.706
phosphorylation GO:0016310 291 0.702
regulation of protein modification process GO:0031399 110 0.677
g2 m transition of mitotic cell cycle GO:0000086 38 0.664
regulation of chromatin modification GO:1903308 23 0.656
mitotic cell cycle process GO:1903047 294 0.634
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.602
protein complex assembly GO:0006461 302 0.597
regulation of phosphate metabolic process GO:0019220 230 0.586
organelle assembly GO:0070925 118 0.577
positive regulation of cellular biosynthetic process GO:0031328 336 0.530
sister chromatid segregation GO:0000819 93 0.529
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.529
positive regulation of cytoskeleton organization GO:0051495 39 0.525
cell cycle dna replication GO:0044786 36 0.522
histone modification GO:0016570 119 0.516
regulation of spindle pole body separation GO:0010695 9 0.513
microtubule organizing center organization GO:0031023 33 0.482
regulation of microtubule based process GO:0032886 32 0.481
spindle pole body organization GO:0051300 33 0.472
protein phosphorylation GO:0006468 197 0.464
regulation of phosphorylation GO:0042325 86 0.446
positive regulation of protein phosphorylation GO:0001934 28 0.435
spindle pole body separation GO:0000073 13 0.425
meiotic cell cycle process GO:1903046 229 0.419
mrna metabolic process GO:0016071 269 0.411
positive regulation of phosphorus metabolic process GO:0010562 147 0.410
positive regulation of gene expression GO:0010628 321 0.403
dna packaging GO:0006323 55 0.393
mrna processing GO:0006397 185 0.389
rna 3 end processing GO:0031123 88 0.375
mrna 3 end processing GO:0031124 54 0.373
positive regulation of spindle pole body separation GO:0010696 7 0.364
establishment of organelle localization GO:0051656 96 0.363
regulation of chromosome condensation GO:0060623 2 0.360
regulation of microtubule cytoskeleton organization GO:0070507 32 0.360
maintenance of location in cell GO:0051651 58 0.356
regulation of dephosphorylation GO:0035303 18 0.355
peptidyl amino acid modification GO:0018193 116 0.344
regulation of mitotic cell cycle GO:0007346 107 0.338
regulation of protein metabolic process GO:0051246 237 0.334
regulation of cellular protein metabolic process GO:0032268 232 0.330
regulation of chromatin organization GO:1902275 23 0.323
meiosis i GO:0007127 92 0.318
chromosome condensation GO:0030261 19 0.313
regulation of phosphorus metabolic process GO:0051174 230 0.308
negative regulation of gene expression GO:0010629 312 0.307
positive regulation of organelle organization GO:0010638 85 0.303
positive regulation of mitotic cell cycle GO:0045931 16 0.299
negative regulation of macromolecule metabolic process GO:0010605 375 0.296
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.294
positive regulation of macromolecule metabolic process GO:0010604 394 0.290
covalent chromatin modification GO:0016569 119 0.283
cellular response to dna damage stimulus GO:0006974 287 0.281
mitotic sister chromatid segregation GO:0000070 85 0.280
positive regulation of nucleic acid templated transcription GO:1903508 286 0.279
positive regulation of phosphorylation GO:0042327 33 0.271
chromatin modification GO:0016568 200 0.268
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.267
regulation of cell cycle GO:0051726 195 0.261
regulation of cell cycle process GO:0010564 150 0.259
mitotic nuclear division GO:0007067 131 0.256
Worm
response to toxic substance GO:0009636 9 0.254
response to chemical GO:0042221 390 0.250
attachment of spindle microtubules to kinetochore GO:0008608 25 0.250
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.245
meiotic nuclear division GO:0007126 163 0.245
Worm
positive regulation of rna metabolic process GO:0051254 294 0.245
positive regulation of cellular component organization GO:0051130 116 0.237
cell cycle checkpoint GO:0000075 82 0.235
chromatin organization GO:0006325 242 0.234
maintenance of protein location in cell GO:0032507 50 0.232
microtubule cytoskeleton organization GO:0000226 109 0.232
maintenance of protein location GO:0045185 53 0.225
dna conformation change GO:0071103 98 0.222
mitotic cytokinesis GO:0000281 58 0.220
chromosome segregation GO:0007059 159 0.219
negative regulation of cell cycle GO:0045786 91 0.216
mitotic cell cycle GO:0000278 306 0.216
cellular component disassembly GO:0022411 86 0.216
spindle checkpoint GO:0031577 35 0.207
regulation of chromosome organization GO:0033044 66 0.205
positive regulation of biosynthetic process GO:0009891 336 0.204
positive regulation of phosphate metabolic process GO:0045937 147 0.197
negative regulation of cell cycle process GO:0010948 86 0.197
nuclear division GO:0000280 263 0.187
Worm
regulation of protein dephosphorylation GO:0035304 4 0.184
maintenance of location GO:0051235 66 0.181
positive regulation of protein metabolic process GO:0051247 93 0.177
cytoskeleton dependent cytokinesis GO:0061640 65 0.175
regulation of mitotic cell cycle phase transition GO:1901990 68 0.174
dephosphorylation GO:0016311 127 0.172
positive regulation of rna biosynthetic process GO:1902680 286 0.169
protein dephosphorylation GO:0006470 40 0.164
regulation of biological quality GO:0065008 391 0.155
regulation of chromosome segregation GO:0051983 44 0.149
response to inorganic substance GO:0010035 47 0.145
regulation of cytoskeleton organization GO:0051493 63 0.145
meiotic g2 mi transition GO:0008315 1 0.144
negative regulation of protein dephosphorylation GO:0035308 2 0.133
non recombinational repair GO:0000726 33 0.132
regulation of protein ubiquitination GO:0031396 20 0.125
macromolecular complex disassembly GO:0032984 80 0.124
regulation of response to dna damage stimulus GO:2001020 17 0.122
response to organic cyclic compound GO:0014070 1 0.120
organelle fission GO:0048285 272 0.119
Worm
positive regulation of cell cycle GO:0045787 32 0.118
negative regulation of cellular metabolic process GO:0031324 407 0.117
mitotic cell cycle checkpoint GO:0007093 56 0.109
organelle localization GO:0051640 128 0.107
negative regulation of cellular catabolic process GO:0031330 43 0.103
positive regulation of protein modification process GO:0031401 49 0.099
cell wall organization GO:0071555 146 0.099
chromatin remodeling GO:0006338 80 0.094
regulation of cell cycle phase transition GO:1901987 70 0.088
positive regulation of cellular protein metabolic process GO:0032270 89 0.088
microtubule polymerization or depolymerization GO:0031109 36 0.087
microtubule based movement GO:0007018 18 0.086
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.086
cellular response to iron ion GO:0071281 3 0.084
negative regulation of microtubule polymerization or depolymerization GO:0031111 7 0.083
regulation of histone modification GO:0031056 18 0.083
cell division GO:0051301 205 0.081
double strand break repair via homologous recombination GO:0000724 54 0.081
negative regulation of mitotic cell cycle GO:0045930 63 0.080
positive regulation of cell cycle process GO:0090068 31 0.080
cellular carbohydrate metabolic process GO:0044262 135 0.080
negative regulation of cell communication GO:0010648 33 0.079
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.078
protein complex biogenesis GO:0070271 314 0.076
positive regulation of transcription dna templated GO:0045893 286 0.075
histone phosphorylation GO:0016572 3 0.075
cation transport GO:0006812 166 0.072
positive regulation of mrna processing GO:0050685 3 0.072
negative regulation of protein phosphorylation GO:0001933 24 0.072
cytokinesis GO:0000910 92 0.070
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.070
protein complex disassembly GO:0043241 70 0.070
microtubule anchoring GO:0034453 25 0.069
meiotic cell cycle phase transition GO:0044771 1 0.069
regulation of cellular localization GO:0060341 50 0.069
spindle organization GO:0007051 37 0.068
cellular response to chemical stimulus GO:0070887 315 0.068
cellular response to organic substance GO:0071310 159 0.068
single organism signaling GO:0044700 208 0.067
signaling GO:0023052 208 0.065
regulation of spindle elongation GO:0032887 3 0.065
protein modification by small protein conjugation GO:0032446 144 0.065
positive regulation of molecular function GO:0044093 185 0.064
asexual reproduction GO:0019954 48 0.063
cellular response to oxidative stress GO:0034599 94 0.063
response to organic substance GO:0010033 182 0.061
regulation of microtubule polymerization or depolymerization GO:0031110 18 0.061
spindle assembly GO:0051225 9 0.061
negative regulation of nucleic acid templated transcription GO:1903507 260 0.060
external encapsulating structure organization GO:0045229 146 0.060
response to metal ion GO:0010038 24 0.059
organic acid metabolic process GO:0006082 352 0.059
spindle stabilization GO:0043146 2 0.058
regulation of dna templated transcription elongation GO:0032784 44 0.057
positive regulation of cellular catabolic process GO:0031331 128 0.056
regulation of mitotic spindle organization GO:0060236 8 0.056
regulation of cellular catabolic process GO:0031329 195 0.055
positive regulation of chromosome segregation GO:0051984 15 0.054
positive regulation of transcription from rna polymerase i promoter GO:0045943 19 0.053
response to abiotic stimulus GO:0009628 159 0.051
cellular protein catabolic process GO:0044257 213 0.050
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.050
regulation of spindle organization GO:0090224 8 0.048
meiotic cell cycle GO:0051321 272 0.048
Worm
regulation of meiotic cell cycle GO:0051445 43 0.048
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.047
positive regulation of dna templated transcription elongation GO:0032786 42 0.047
glycerolipid metabolic process GO:0046486 108 0.046
positive regulation of histone modification GO:0031058 12 0.045
alpha amino acid metabolic process GO:1901605 124 0.045
regulation of organelle organization GO:0033043 243 0.045
ras protein signal transduction GO:0007265 29 0.044
growth GO:0040007 157 0.044
single organism membrane organization GO:0044802 275 0.044
cellular protein complex disassembly GO:0043624 42 0.044
transcription from rna polymerase i promoter GO:0006360 63 0.044
negative regulation of cellular biosynthetic process GO:0031327 312 0.043
cell communication GO:0007154 345 0.042
single organism carbohydrate metabolic process GO:0044723 237 0.042
positive regulation of dna replication GO:0045740 11 0.042
negative regulation of cellular protein metabolic process GO:0032269 85 0.041
nuclear dna replication GO:0033260 27 0.041
dna damage checkpoint GO:0000077 29 0.040
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 27 0.040
dna templated transcription elongation GO:0006354 91 0.040
response to external stimulus GO:0009605 158 0.040
negative regulation of phosphorylation GO:0042326 28 0.039
negative regulation of signal transduction GO:0009968 30 0.039
negative regulation of catabolic process GO:0009895 43 0.039
nuclear transport GO:0051169 165 0.038
regulation of transcription from rna polymerase i promoter GO:0006356 36 0.037
negative regulation of phosphate metabolic process GO:0045936 49 0.037
protein modification by small protein conjugation or removal GO:0070647 172 0.037
negative regulation of molecular function GO:0044092 68 0.037
peptidyl serine modification GO:0018209 7 0.037
purine containing compound metabolic process GO:0072521 400 0.036
negative regulation of cell cycle phase transition GO:1901988 59 0.036
nucleoside catabolic process GO:0009164 335 0.036
nucleocytoplasmic transport GO:0006913 163 0.036
small gtpase mediated signal transduction GO:0007264 36 0.035
positive regulation of chromatin modification GO:1903310 13 0.035
metal ion transport GO:0030001 75 0.035
cellular response to hypoxia GO:0071456 4 0.035
cytoskeleton organization GO:0007010 230 0.035
protein ubiquitination GO:0016567 118 0.035
cellular response to oxygen containing compound GO:1901701 43 0.035
regulation of signal transduction GO:0009966 114 0.034
response to hypoxia GO:0001666 4 0.034
regulation of protein depolymerization GO:1901879 12 0.033
positive regulation of protein modification by small protein conjugation or removal GO:1903322 12 0.033
response to iron ion GO:0010039 3 0.033
response to transition metal nanoparticle GO:1990267 16 0.033
mitotic spindle checkpoint GO:0071174 34 0.033
positive regulation of translation GO:0045727 34 0.033
multi organism process GO:0051704 233 0.032
double strand break repair GO:0006302 105 0.032
nucleobase containing small molecule metabolic process GO:0055086 491 0.030
response to oxygen containing compound GO:1901700 61 0.030
intracellular protein transport GO:0006886 319 0.030
regulation of meiosis GO:0040020 42 0.030
positive regulation of dna metabolic process GO:0051054 26 0.029
fungal type cell wall organization or biogenesis GO:0071852 169 0.028
regulation of catabolic process GO:0009894 199 0.027
developmental process GO:0032502 261 0.027
Worm
negative regulation of rna metabolic process GO:0051253 262 0.026
positive regulation of lipid catabolic process GO:0050996 4 0.026
developmental growth GO:0048589 3 0.026
mitotic spindle organization GO:0007052 30 0.026
fungal type cell wall organization GO:0031505 145 0.025
dna dependent dna replication GO:0006261 115 0.025
mitotic spindle organization in nucleus GO:0030472 9 0.025
purine ribonucleotide catabolic process GO:0009154 327 0.025
positive regulation of catalytic activity GO:0043085 178 0.025
response to lipid GO:0033993 5 0.025
negative regulation of phosphorus metabolic process GO:0010563 49 0.025
cellular component movement GO:0006928 20 0.025
peptidyl serine phosphorylation GO:0018105 7 0.025
dna replication initiation GO:0006270 48 0.024
programmed cell death GO:0012501 30 0.024
regulation of response to stimulus GO:0048583 157 0.024
regulation of attachment of spindle microtubules to kinetochore GO:0051988 11 0.024
regulation of dna dependent dna replication initiation GO:0030174 21 0.024
positive regulation of intracellular protein transport GO:0090316 3 0.024
regulation of cell communication GO:0010646 124 0.024
cellular carbohydrate biosynthetic process GO:0034637 49 0.024
negative regulation of transcription dna templated GO:0045892 258 0.024
recombinational repair GO:0000725 64 0.023
regulation of glucose metabolic process GO:0010906 27 0.023
organophosphate biosynthetic process GO:0090407 182 0.023
carbohydrate biosynthetic process GO:0016051 82 0.023
small molecule biosynthetic process GO:0044283 258 0.023
dna replication GO:0006260 147 0.023
positive regulation of mrna 3 end processing GO:0031442 1 0.022
cell death GO:0008219 30 0.022
autophagy GO:0006914 106 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.022
regulation of nuclear division GO:0051783 103 0.022
chromosome localization GO:0050000 20 0.022
dna biosynthetic process GO:0071897 33 0.022
response to acid chemical GO:0001101 19 0.022
phosphorylation of rna polymerase ii c terminal domain GO:0070816 20 0.021
negative regulation of protein metabolic process GO:0051248 85 0.021
signal transduction GO:0007165 208 0.021
regulation of mrna metabolic process GO:1903311 17 0.021
positive regulation of chromosome organization GO:2001252 20 0.021
protein catabolic process GO:0030163 221 0.020
multi organism reproductive process GO:0044703 216 0.020
posttranscriptional regulation of gene expression GO:0010608 115 0.019
protein dna complex subunit organization GO:0071824 153 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.019
nitrogen compound transport GO:0071705 212 0.019
positive regulation of intracellular transport GO:0032388 4 0.018
apoptotic process GO:0006915 30 0.018
reproductive process GO:0022414 248 0.018
rna capping GO:0036260 13 0.018
positive regulation of catabolic process GO:0009896 135 0.018
cellular polysaccharide biosynthetic process GO:0033692 38 0.018
glycogen biosynthetic process GO:0005978 17 0.018
negative regulation of protein depolymerization GO:1901880 12 0.018
vacuole organization GO:0007033 75 0.018
cellular macromolecule catabolic process GO:0044265 363 0.017
anatomical structure development GO:0048856 160 0.017
Worm
macroautophagy GO:0016236 55 0.017
cellular response to nutrient levels GO:0031669 144 0.017
regulation of dna replication GO:0006275 51 0.017
positive regulation of mrna metabolic process GO:1903313 7 0.017
negative regulation of protein complex disassembly GO:0043242 14 0.017
positive regulation of cell death GO:0010942 3 0.017
synaptonemal complex organization GO:0070193 16 0.017
regulation of intracellular signal transduction GO:1902531 78 0.017
regulation of protein complex assembly GO:0043254 77 0.017
glucan biosynthetic process GO:0009250 26 0.017
response to drug GO:0042493 41 0.016
double strand break repair via nonhomologous end joining GO:0006303 27 0.016
negative regulation of rna biosynthetic process GO:1902679 260 0.016
response to oxidative stress GO:0006979 99 0.016
vesicle mediated transport GO:0016192 335 0.016
cellular protein complex assembly GO:0043623 209 0.016
regulation of cellular component organization GO:0051128 334 0.016
regulation of translation GO:0006417 89 0.016
regulation of mitotic spindle elongation GO:0032888 3 0.016
protein transport GO:0015031 345 0.016
macromolecule catabolic process GO:0009057 383 0.016
negative regulation of gene expression epigenetic GO:0045814 147 0.015
regulation of dna repair GO:0006282 14 0.015
regulation of translational elongation GO:0006448 25 0.015
budding cell apical bud growth GO:0007118 19 0.015
single organism developmental process GO:0044767 258 0.015
Worm
nucleotide catabolic process GO:0009166 330 0.015
microtubule depolymerization GO:0007019 8 0.014
positive regulation of apoptotic process GO:0043065 3 0.014
sexual reproduction GO:0019953 216 0.014
cellular component assembly involved in morphogenesis GO:0010927 73 0.014
negative regulation of organelle organization GO:0010639 103 0.014
mitotic metaphase plate congression GO:0007080 8 0.014
regulation of cellular component biogenesis GO:0044087 112 0.014
cellular response to external stimulus GO:0071496 150 0.014
positive regulation of protein ubiquitination GO:0031398 7 0.014
negative regulation of signaling GO:0023057 30 0.014
negative regulation of kinase activity GO:0033673 24 0.014
regulation of lipid metabolic process GO:0019216 45 0.013
regulation of gene silencing GO:0060968 41 0.013
negative regulation of intracellular signal transduction GO:1902532 27 0.013
g2 dna damage checkpoint GO:0031572 1 0.013
regulation of autophagy GO:0010506 18 0.013
filamentous growth GO:0030447 124 0.013
regulation of protein complex disassembly GO:0043244 23 0.013
microtubule based process GO:0007017 117 0.013
regulation of carbohydrate metabolic process GO:0006109 43 0.013
chromosome separation GO:0051304 33 0.013
sister chromatid cohesion GO:0007062 49 0.013
mitotic spindle elongation GO:0000022 14 0.013
positive regulation of cytoplasmic transport GO:1903651 4 0.013
response to nutrient levels GO:0031667 150 0.013
response to reactive oxygen species GO:0000302 22 0.012
negative regulation of protein modification process GO:0031400 37 0.012
regulation of signaling GO:0023051 119 0.012
cell wall organization or biogenesis GO:0071554 190 0.012
purine nucleotide catabolic process GO:0006195 328 0.012
gene silencing GO:0016458 151 0.012
death GO:0016265 30 0.012
chromatin silencing GO:0006342 147 0.012
dna recombination GO:0006310 172 0.012
positive regulation of programmed cell death GO:0043068 3 0.012
regulation of lipid catabolic process GO:0050994 4 0.012
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 79 0.012
regulation of mitosis GO:0007088 65 0.012
ion transport GO:0006811 274 0.011
regulation of localization GO:0032879 127 0.011
fungal type cell wall biogenesis GO:0009272 80 0.011
carboxylic acid biosynthetic process GO:0046394 152 0.011
proteasomal protein catabolic process GO:0010498 141 0.011
ascospore formation GO:0030437 107 0.011
mitochondrion organization GO:0007005 261 0.011
protein localization to chromosome GO:0034502 28 0.011
single organism membrane fusion GO:0044801 71 0.011
reproduction of a single celled organism GO:0032505 191 0.011
purine containing compound catabolic process GO:0072523 332 0.011
regulation of binding GO:0051098 11 0.011
regulation of transport GO:0051049 85 0.011
organic acid biosynthetic process GO:0016053 152 0.011
regulation of cellular amine metabolic process GO:0033238 21 0.011
single organism catabolic process GO:0044712 619 0.010
organophosphate metabolic process GO:0019637 597 0.010
positive regulation of protein localization to nucleus GO:1900182 7 0.010
negative regulation of catalytic activity GO:0043086 60 0.010
mitotic spindle stabilization GO:0043148 2 0.010

CKS1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org