Saccharomyces cerevisiae

57 known processes

OTU1 (YFL044C)

Otu1p

OTU1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.964
modification dependent macromolecule catabolic process GO:0043632 203 0.957
protein catabolic process GO:0030163 221 0.871
cellular protein catabolic process GO:0044257 213 0.826
modification dependent protein catabolic process GO:0019941 181 0.783
er associated ubiquitin dependent protein catabolic process GO:0030433 46 0.783
proteasomal protein catabolic process GO:0010498 141 0.774
ubiquitin dependent protein catabolic process GO:0006511 181 0.744
macromolecule catabolic process GO:0009057 383 0.736
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.699
proteolysis GO:0006508 268 0.642
cellular macromolecule catabolic process GO:0044265 363 0.635
cellular response to chemical stimulus GO:0070887 315 0.425
response to chemical GO:0042221 390 0.356
protein transport GO:0015031 345 0.317
membrane organization GO:0061024 276 0.262
protein localization to nucleus GO:0034504 74 0.241
protein localization to organelle GO:0033365 337 0.229
anatomical structure formation involved in morphogenesis GO:0048646 136 0.227
intracellular protein transport GO:0006886 319 0.215
rrna metabolic process GO:0016072 244 0.214
carbohydrate metabolic process GO:0005975 252 0.202
single organism membrane organization GO:0044802 275 0.189
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.188
sporulation GO:0043934 132 0.185
response to organic substance GO:0010033 182 0.173
sporulation resulting in formation of a cellular spore GO:0030435 129 0.159
single organism signaling GO:0044700 208 0.156
meiotic cell cycle GO:0051321 272 0.147
single organism carbohydrate metabolic process GO:0044723 237 0.146
rna catabolic process GO:0006401 118 0.143
positive regulation of macromolecule metabolic process GO:0010604 394 0.137
single organism cellular localization GO:1902580 375 0.130
negative regulation of gene expression GO:0010629 312 0.126
establishment of protein localization GO:0045184 367 0.121
protein ubiquitination GO:0016567 118 0.119
protein modification by small protein conjugation or removal GO:0070647 172 0.118
negative regulation of macromolecule metabolic process GO:0010605 375 0.114
regulation of protein localization GO:0032880 62 0.113
protein targeting GO:0006605 272 0.113
cellular response to dna damage stimulus GO:0006974 287 0.103
cellular response to organic substance GO:0071310 159 0.103
regulation of biological quality GO:0065008 391 0.102
aromatic compound catabolic process GO:0019439 491 0.101
chromatin modification GO:0016568 200 0.098
glycosylation GO:0070085 66 0.097
negative regulation of cellular metabolic process GO:0031324 407 0.097
cellular developmental process GO:0048869 191 0.095
cell differentiation GO:0030154 161 0.095
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.085
homeostatic process GO:0042592 227 0.081
meiotic cell cycle process GO:1903046 229 0.081
cell communication GO:0007154 345 0.080
misfolded or incompletely synthesized protein catabolic process GO:0006515 21 0.079
mitotic cell cycle GO:0000278 306 0.077
negative regulation of biosynthetic process GO:0009890 312 0.074
regulation of cell cycle GO:0051726 195 0.074
regulation of cellular localization GO:0060341 50 0.072
ribosome biogenesis GO:0042254 335 0.071
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.071
negative regulation of nucleic acid templated transcription GO:1903507 260 0.070
response to misfolded protein GO:0051788 11 0.066
positive regulation of gene expression GO:0010628 321 0.065
cellular component disassembly GO:0022411 86 0.065
regulation of organelle organization GO:0033043 243 0.064
cellular nitrogen compound catabolic process GO:0044270 494 0.062
organic acid biosynthetic process GO:0016053 152 0.062
negative regulation of rna biosynthetic process GO:1902679 260 0.062
mitochondrion organization GO:0007005 261 0.061
regulation of cellular component organization GO:0051128 334 0.061
cell development GO:0048468 107 0.061
nucleobase containing compound catabolic process GO:0034655 479 0.061
heterocycle catabolic process GO:0046700 494 0.060
regulation of cellular protein metabolic process GO:0032268 232 0.059
negative regulation of cellular biosynthetic process GO:0031327 312 0.059
regulation of gene expression epigenetic GO:0040029 147 0.058
single organism catabolic process GO:0044712 619 0.058
cellular homeostasis GO:0019725 138 0.058
negative regulation of transcription dna templated GO:0045892 258 0.058
gene silencing GO:0016458 151 0.058
negative regulation of gene expression epigenetic GO:0045814 147 0.058
regulation of cellular catabolic process GO:0031329 195 0.058
single organism developmental process GO:0044767 258 0.056
organic cyclic compound catabolic process GO:1901361 499 0.056
positive regulation of biosynthetic process GO:0009891 336 0.056
cell growth GO:0016049 89 0.055
negative regulation of rna metabolic process GO:0051253 262 0.055
carbohydrate derivative metabolic process GO:1901135 549 0.055
organelle fission GO:0048285 272 0.054
signaling GO:0023052 208 0.053
positive regulation of cellular biosynthetic process GO:0031328 336 0.052
negative regulation of cell cycle GO:0045786 91 0.051
response to abiotic stimulus GO:0009628 159 0.051
monocarboxylic acid metabolic process GO:0032787 122 0.050
response to topologically incorrect protein GO:0035966 38 0.050
chromatin organization GO:0006325 242 0.050
protein modification by small protein conjugation GO:0032446 144 0.050
macromolecular complex disassembly GO:0032984 80 0.049
nucleoside phosphate metabolic process GO:0006753 458 0.048
cellular response to starvation GO:0009267 90 0.047
organelle localization GO:0051640 128 0.047
anatomical structure development GO:0048856 160 0.047
histone modification GO:0016570 119 0.047
metal ion homeostasis GO:0055065 79 0.046
ribosome associated ubiquitin dependent protein catabolic process GO:1990116 7 0.046
fatty acid metabolic process GO:0006631 51 0.046
regulation of catalytic activity GO:0050790 307 0.046
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.045
fungal type cell wall organization or biogenesis GO:0071852 169 0.045
establishment of protein localization to membrane GO:0090150 99 0.045
mitotic cell cycle process GO:1903047 294 0.044
cellular carbohydrate metabolic process GO:0044262 135 0.042
negative regulation of cell cycle process GO:0010948 86 0.042
negative regulation of molecular function GO:0044092 68 0.041
cellular response to nutrient levels GO:0031669 144 0.040
multi organism process GO:0051704 233 0.040
oxoacid metabolic process GO:0043436 351 0.040
anatomical structure morphogenesis GO:0009653 160 0.040
protein folding GO:0006457 94 0.039
regulation of localization GO:0032879 127 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.039
carbohydrate biosynthetic process GO:0016051 82 0.038
regulation of catabolic process GO:0009894 199 0.038
protein complex disassembly GO:0043241 70 0.038
programmed cell death GO:0012501 30 0.038
glycoprotein metabolic process GO:0009100 62 0.038
cytoplasm associated proteasomal ubiquitin dependent protein catabolic process GO:0071629 5 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.037
ascospore formation GO:0030437 107 0.035
protein glycosylation GO:0006486 57 0.035
reproductive process GO:0022414 248 0.035
posttranscriptional regulation of gene expression GO:0010608 115 0.034
protein targeting to er GO:0045047 39 0.034
ncrna catabolic process GO:0034661 33 0.034
carbohydrate derivative biosynthetic process GO:1901137 181 0.034
purine ribonucleotide metabolic process GO:0009150 372 0.033
cellular lipid metabolic process GO:0044255 229 0.033
regulation of protein modification process GO:0031399 110 0.032
regulation of protein localization to nucleus GO:1900180 16 0.032
rrna catabolic process GO:0016075 31 0.032
regulation of cell cycle process GO:0010564 150 0.032
positive regulation of rna metabolic process GO:0051254 294 0.032
oxidation reduction process GO:0055114 353 0.031
regulation of proteasomal protein catabolic process GO:0061136 34 0.031
mitotic cell cycle phase transition GO:0044772 141 0.031
protein localization to membrane GO:0072657 102 0.031
small molecule biosynthetic process GO:0044283 258 0.031
establishment of protein localization to organelle GO:0072594 278 0.031
regulation of molecular function GO:0065009 320 0.031
sexual sporulation GO:0034293 113 0.030
cellular ketone metabolic process GO:0042180 63 0.030
response to uv GO:0009411 4 0.030
developmental process involved in reproduction GO:0003006 159 0.029
positive regulation of rna biosynthetic process GO:1902680 286 0.029
establishment of organelle localization GO:0051656 96 0.029
negative regulation of cellular component organization GO:0051129 109 0.029
chemical homeostasis GO:0048878 137 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.029
cellular cation homeostasis GO:0030003 100 0.029
gene silencing by rna GO:0031047 3 0.029
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.029
covalent chromatin modification GO:0016569 119 0.028
positive regulation of nucleic acid templated transcription GO:1903508 286 0.028
developmental process GO:0032502 261 0.028
cell cycle phase transition GO:0044770 144 0.028
cell division GO:0051301 205 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.028
cellular chemical homeostasis GO:0055082 123 0.028
nucleobase containing small molecule metabolic process GO:0055086 491 0.028
nuclear division GO:0000280 263 0.028
translation GO:0006412 230 0.027
positive regulation of transcription dna templated GO:0045893 286 0.027
chromosome segregation GO:0007059 159 0.027
regulation of growth GO:0040008 50 0.026
multi organism reproductive process GO:0044703 216 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.026
organic acid catabolic process GO:0016054 71 0.026
protein targeting to membrane GO:0006612 52 0.026
growth GO:0040007 157 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.025
protein transmembrane transport GO:0071806 82 0.025
cellular response to topologically incorrect protein GO:0035967 32 0.025
regulation of cellular protein catabolic process GO:1903362 36 0.025
ribonucleoside metabolic process GO:0009119 389 0.025
negative regulation of cell division GO:0051782 66 0.025
regulation of protein catabolic process GO:0042176 40 0.025
cellular response to oxidative stress GO:0034599 94 0.024
regulation of transport GO:0051049 85 0.024
regulation of proteolysis GO:0030162 44 0.024
cellular ion homeostasis GO:0006873 112 0.024
meiotic nuclear division GO:0007126 163 0.024
nucleoside metabolic process GO:0009116 394 0.024
phosphorylation GO:0016310 291 0.023
glucan metabolic process GO:0044042 44 0.023
cellular polysaccharide metabolic process GO:0044264 55 0.023
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.023
nucleotide metabolic process GO:0009117 453 0.023
organic acid metabolic process GO:0006082 352 0.023
positive regulation of cellular catabolic process GO:0031331 128 0.023
ribose phosphate metabolic process GO:0019693 384 0.023
purine nucleoside monophosphate metabolic process GO:0009126 262 0.022
ncrna processing GO:0034470 330 0.022
positive regulation of growth GO:0045927 19 0.022
filamentous growth of a population of unicellular organisms GO:0044182 109 0.021
positive regulation of apoptotic process GO:0043065 3 0.021
chromatin silencing GO:0006342 147 0.021
response to starvation GO:0042594 96 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.021
cation homeostasis GO:0055080 105 0.021
nucleocytoplasmic transport GO:0006913 163 0.020
regulation of cell size GO:0008361 30 0.020
macromolecule glycosylation GO:0043413 57 0.020
lipid biosynthetic process GO:0008610 170 0.020
organophosphate metabolic process GO:0019637 597 0.020
organelle assembly GO:0070925 118 0.020
negative regulation of response to stimulus GO:0048585 40 0.020
regulation of translation GO:0006417 89 0.020
cellular response to arsenic containing substance GO:0071243 7 0.020
carbohydrate derivative catabolic process GO:1901136 339 0.020
positive regulation of catalytic activity GO:0043085 178 0.020
rna splicing via transesterification reactions GO:0000375 118 0.019
purine ribonucleoside metabolic process GO:0046128 380 0.019
regulation of protein metabolic process GO:0051246 237 0.019
positive regulation of protein localization to nucleus GO:1900182 7 0.019
ribonucleoprotein complex subunit organization GO:0071826 152 0.019
fungal type cell wall organization GO:0031505 145 0.019
negative regulation of protein metabolic process GO:0051248 85 0.019
response to inorganic substance GO:0010035 47 0.019
rrna processing GO:0006364 227 0.019
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 24 0.018
response to metal ion GO:0010038 24 0.018
negative regulation of mitotic cell cycle GO:0045930 63 0.018
purine containing compound catabolic process GO:0072523 332 0.018
nucleoside triphosphate catabolic process GO:0009143 329 0.018
cellular amide metabolic process GO:0043603 59 0.018
vesicle mediated transport GO:0016192 335 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
single organism membrane fusion GO:0044801 71 0.018
ribonucleoside triphosphate catabolic process GO:0009203 327 0.017
maintenance of location in cell GO:0051651 58 0.017
protein complex assembly GO:0006461 302 0.017
peptidyl amino acid modification GO:0018193 116 0.017
regulation of mitotic cell cycle phase transition GO:1901990 68 0.017
nucleotide catabolic process GO:0009166 330 0.017
regulation of mitotic cell cycle GO:0007346 107 0.017
cellular glucan metabolic process GO:0006073 44 0.017
regulation of protein ubiquitination GO:0031396 20 0.017
response to unfolded protein GO:0006986 29 0.017
external encapsulating structure organization GO:0045229 146 0.017
polysaccharide metabolic process GO:0005976 60 0.016
positive regulation of catabolic process GO:0009896 135 0.016
maintenance of protein location GO:0045185 53 0.016
cellular response to oxygen containing compound GO:1901701 43 0.016
nucleoside phosphate catabolic process GO:1901292 331 0.016
reproductive process in single celled organism GO:0022413 145 0.016
mrna catabolic process GO:0006402 93 0.016
apoptotic process GO:0006915 30 0.016
negative regulation of cell cycle phase transition GO:1901988 59 0.016
response to oxidative stress GO:0006979 99 0.016
organelle fusion GO:0048284 85 0.016
positive regulation of secretion GO:0051047 2 0.016
purine nucleotide catabolic process GO:0006195 328 0.016
glycosyl compound catabolic process GO:1901658 335 0.016
ribonucleotide metabolic process GO:0009259 377 0.016
regulation of lipid biosynthetic process GO:0046890 32 0.016
regulation of dna metabolic process GO:0051052 100 0.016
purine containing compound metabolic process GO:0072521 400 0.016
regulation of cellular ketone metabolic process GO:0010565 42 0.015
purine nucleoside metabolic process GO:0042278 380 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
polysaccharide biosynthetic process GO:0000271 39 0.015
positive regulation of molecular function GO:0044093 185 0.015
sulfur compound metabolic process GO:0006790 95 0.015
mitotic sister chromatid segregation GO:0000070 85 0.015
endosomal transport GO:0016197 86 0.015
transition metal ion homeostasis GO:0055076 59 0.015
positive regulation of organelle organization GO:0010638 85 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.015
positive regulation of hydrolase activity GO:0051345 112 0.015
cellular protein complex disassembly GO:0043624 42 0.015
response to osmotic stress GO:0006970 83 0.015
regulation of cell division GO:0051302 113 0.014
ribonucleoside triphosphate metabolic process GO:0009199 356 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.014
death GO:0016265 30 0.014
glycoprotein biosynthetic process GO:0009101 61 0.014
cellular response to external stimulus GO:0071496 150 0.014
maintenance of location GO:0051235 66 0.014
nucleoside triphosphate metabolic process GO:0009141 364 0.014
autophagy GO:0006914 106 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 13 0.014
regulation of filamentous growth GO:0010570 38 0.014
protein processing GO:0016485 64 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.014
endosome transport via multivesicular body sorting pathway GO:0032509 27 0.014
positive regulation of intracellular transport GO:0032388 4 0.014
cellular amino acid catabolic process GO:0009063 48 0.014
cell death GO:0008219 30 0.014
protein localization to vacuole GO:0072665 92 0.014
organophosphate catabolic process GO:0046434 338 0.013
purine ribonucleoside catabolic process GO:0046130 330 0.013
purine nucleoside catabolic process GO:0006152 330 0.013
cellular component assembly involved in morphogenesis GO:0010927 73 0.013
cell wall organization or biogenesis GO:0071554 190 0.013
er to golgi vesicle mediated transport GO:0006888 86 0.013
ribonucleotide catabolic process GO:0009261 327 0.013
coenzyme biosynthetic process GO:0009108 66 0.013
positive regulation of nucleoside metabolic process GO:0045979 97 0.013
regulation of protein complex assembly GO:0043254 77 0.013
ion homeostasis GO:0050801 118 0.013
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.013
single organism nuclear import GO:1902593 56 0.013
iron ion homeostasis GO:0055072 34 0.013
response to external stimulus GO:0009605 158 0.013
organonitrogen compound catabolic process GO:1901565 404 0.013
positive regulation of cell death GO:0010942 3 0.013
small molecule catabolic process GO:0044282 88 0.013
mitochondrial respiratory chain complex assembly GO:0033108 36 0.013
response to organic cyclic compound GO:0014070 1 0.012
purine nucleoside monophosphate catabolic process GO:0009128 224 0.012
regulation of nucleoside metabolic process GO:0009118 106 0.012
macroautophagy GO:0016236 55 0.012
negative regulation of organelle organization GO:0010639 103 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.012
positive regulation of transport GO:0051050 32 0.012
nuclear transport GO:0051169 165 0.012
response to temperature stimulus GO:0009266 74 0.012
maintenance of protein location in cell GO:0032507 50 0.012
regulation of signal transduction GO:0009966 114 0.012
regulation of cellular component biogenesis GO:0044087 112 0.012
positive regulation of programmed cell death GO:0043068 3 0.012
ribonucleoprotein complex assembly GO:0022618 143 0.012
cellular response to extracellular stimulus GO:0031668 150 0.012
peptide metabolic process GO:0006518 28 0.012
ribonucleoside catabolic process GO:0042454 332 0.012
cellular component macromolecule biosynthetic process GO:0070589 24 0.012
protein localization to endoplasmic reticulum GO:0070972 47 0.012
microtubule cytoskeleton organization GO:0000226 109 0.012
regulation of dna replication GO:0006275 51 0.012
cytoskeleton organization GO:0007010 230 0.012
retrograde protein transport er to cytosol GO:0030970 8 0.012
negative regulation of nuclear division GO:0051784 62 0.012
protein maturation GO:0051604 76 0.012
regulation of sodium ion transport GO:0002028 1 0.012
glycosyl compound metabolic process GO:1901657 398 0.011
purine nucleoside triphosphate metabolic process GO:0009144 356 0.011
nuclear import GO:0051170 57 0.011
reproduction of a single celled organism GO:0032505 191 0.011
ribonucleoside monophosphate catabolic process GO:0009158 224 0.011
regulation of response to stimulus GO:0048583 157 0.011
cell wall organization GO:0071555 146 0.011
nucleoside catabolic process GO:0009164 335 0.011
ribonucleoside monophosphate metabolic process GO:0009161 265 0.011
response to endoplasmic reticulum stress GO:0034976 23 0.011
dna repair GO:0006281 236 0.011
protein modification by small protein removal GO:0070646 29 0.011
regulation of hydrolase activity GO:0051336 133 0.011
cellular amino acid metabolic process GO:0006520 225 0.011
carboxylic acid biosynthetic process GO:0046394 152 0.011
response to arsenic containing substance GO:0046685 12 0.011
regulation of metal ion transport GO:0010959 2 0.011
golgi vesicle transport GO:0048193 188 0.011
signal transduction GO:0007165 208 0.011
regulation of signaling GO:0023051 119 0.011
response to hypoxia GO:0001666 4 0.011
response to nutrient levels GO:0031667 150 0.011
intracellular protein transmembrane transport GO:0065002 80 0.011
regulation of cellular response to drug GO:2001038 3 0.011
rna splicing GO:0008380 131 0.011
nucleotide biosynthetic process GO:0009165 79 0.011
microtubule based process GO:0007017 117 0.010
positive regulation of secretion by cell GO:1903532 2 0.010
nuclear export GO:0051168 124 0.010
energy derivation by oxidation of organic compounds GO:0015980 125 0.010
invasive growth in response to glucose limitation GO:0001403 61 0.010
intracellular signal transduction GO:0035556 112 0.010
sulfur compound biosynthetic process GO:0044272 53 0.010
cellular iron ion homeostasis GO:0006879 34 0.010
mitotic spindle organization GO:0007052 30 0.010
cellular response to osmotic stress GO:0071470 50 0.010
organelle disassembly GO:1903008 13 0.010
filamentous growth GO:0030447 124 0.010
regulation of dna templated transcription in response to stress GO:0043620 51 0.010

OTU1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022