Saccharomyces cerevisiae

56 known processes

PEX2 (YJL210W)

Pex2p

(Aliases: PAS5,CRT1)

PEX2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular protein transmembrane import GO:0044743 67 0.931
transmembrane transport GO:0055085 349 0.927
protein transmembrane transport GO:0071806 82 0.919
intracellular protein transmembrane transport GO:0065002 80 0.915
establishment of protein localization GO:0045184 367 0.903
protein localization to peroxisome GO:0072662 22 0.874
protein targeting to peroxisome GO:0006625 22 0.850
peroxisome organization GO:0007031 68 0.831
peroxisomal transport GO:0043574 22 0.795
protein targeting GO:0006605 272 0.785
establishment of protein localization to peroxisome GO:0072663 22 0.772
protein import GO:0017038 122 0.766
protein import into peroxisome matrix GO:0016558 20 0.726
protein transport GO:0015031 345 0.700
establishment of protein localization to organelle GO:0072594 278 0.539
intracellular protein transport GO:0006886 319 0.516
protein localization to organelle GO:0033365 337 0.498
single organism cellular localization GO:1902580 375 0.481
protein ubiquitination GO:0016567 118 0.314
protein modification by small protein conjugation or removal GO:0070647 172 0.241
protein import into peroxisome matrix docking GO:0016560 5 0.224
cellular macromolecule catabolic process GO:0044265 363 0.188
histone modification GO:0016570 119 0.153
modification dependent macromolecule catabolic process GO:0043632 203 0.149
protein polyubiquitination GO:0000209 20 0.143
protein modification by small protein conjugation GO:0032446 144 0.126
dna repair GO:0006281 236 0.120
protein localization to membrane GO:0072657 102 0.115
microtubule cytoskeleton organization GO:0000226 109 0.110
modification dependent protein catabolic process GO:0019941 181 0.109
purine containing compound metabolic process GO:0072521 400 0.100
lipid metabolic process GO:0006629 269 0.099
protein catabolic process GO:0030163 221 0.098
protein monoubiquitination GO:0006513 13 0.097
proteolysis GO:0006508 268 0.094
purine nucleoside triphosphate metabolic process GO:0009144 356 0.093
negative regulation of cellular metabolic process GO:0031324 407 0.092
protein targeting to membrane GO:0006612 52 0.091
protein import into peroxisome matrix receptor recycling GO:0016562 5 0.089
response to chemical GO:0042221 390 0.086
cell communication GO:0007154 345 0.086
signaling GO:0023052 208 0.085
cellular lipid metabolic process GO:0044255 229 0.083
nucleoside metabolic process GO:0009116 394 0.082
nuclear division GO:0000280 263 0.080
organelle fission GO:0048285 272 0.080
regulation of signaling GO:0023051 119 0.079
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.078
negative regulation of nucleic acid templated transcription GO:1903507 260 0.077
negative regulation of biosynthetic process GO:0009890 312 0.072
nucleoside monophosphate metabolic process GO:0009123 267 0.071
macromolecule catabolic process GO:0009057 383 0.070
nucleotide metabolic process GO:0009117 453 0.068
vesicle mediated transport GO:0016192 335 0.068
regulation of cell communication GO:0010646 124 0.068
cell division GO:0051301 205 0.065
cellular lipid catabolic process GO:0044242 33 0.063
negative regulation of macromolecule metabolic process GO:0010605 375 0.061
glycosyl compound metabolic process GO:1901657 398 0.061
single organism catabolic process GO:0044712 619 0.061
negative regulation of gene expression GO:0010629 312 0.061
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.060
membrane docking GO:0022406 22 0.060
purine ribonucleotide biosynthetic process GO:0009152 39 0.059
regulation of cellular component organization GO:0051128 334 0.059
regulation of biological quality GO:0065008 391 0.057
carbohydrate derivative biosynthetic process GO:1901137 181 0.056
proton transport GO:0015992 61 0.055
ubiquitin dependent protein catabolic process GO:0006511 181 0.055
mitotic recombination GO:0006312 55 0.055
ribose phosphate metabolic process GO:0019693 384 0.055
meiotic cell cycle GO:0051321 272 0.055
cellular nitrogen compound catabolic process GO:0044270 494 0.053
cellular response to chemical stimulus GO:0070887 315 0.053
negative regulation of cellular component organization GO:0051129 109 0.052
nucleobase containing compound catabolic process GO:0034655 479 0.050
nucleoside phosphate metabolic process GO:0006753 458 0.049
purine nucleotide metabolic process GO:0006163 376 0.048
organophosphate metabolic process GO:0019637 597 0.047
regulation of phosphate metabolic process GO:0019220 230 0.047
aromatic compound catabolic process GO:0019439 491 0.047
microtubule based process GO:0007017 117 0.046
purine nucleotide biosynthetic process GO:0006164 41 0.046
covalent chromatin modification GO:0016569 119 0.045
mitotic cell cycle process GO:1903047 294 0.044
ribonucleoside metabolic process GO:0009119 389 0.043
negative regulation of rna metabolic process GO:0051253 262 0.042
single organism signaling GO:0044700 208 0.042
negative regulation of gene expression epigenetic GO:0045814 147 0.041
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.041
regulation of phosphorus metabolic process GO:0051174 230 0.041
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.040
ribonucleoside monophosphate metabolic process GO:0009161 265 0.039
regulation of cell cycle phase transition GO:1901987 70 0.039
cellular protein catabolic process GO:0044257 213 0.038
ion transmembrane transport GO:0034220 200 0.038
chromatin modification GO:0016568 200 0.038
cellular divalent inorganic cation homeostasis GO:0072503 21 0.038
positive regulation of molecular function GO:0044093 185 0.038
regulation of localization GO:0032879 127 0.037
response to abiotic stimulus GO:0009628 159 0.037
regulation of mitotic cell cycle phase transition GO:1901990 68 0.036
organophosphate ester transport GO:0015748 45 0.035
fungal type cell wall organization GO:0031505 145 0.035
nucleotide biosynthetic process GO:0009165 79 0.035
translation GO:0006412 230 0.034
trna processing GO:0008033 101 0.033
ribonucleotide metabolic process GO:0009259 377 0.033
regulation of gene expression epigenetic GO:0040029 147 0.033
nucleobase containing compound transport GO:0015931 124 0.033
purine nucleoside metabolic process GO:0042278 380 0.033
mitotic cell cycle GO:0000278 306 0.032
mitotic cell cycle phase transition GO:0044772 141 0.032
dna integrity checkpoint GO:0031570 41 0.032
homeostatic process GO:0042592 227 0.032
purine ribonucleotide metabolic process GO:0009150 372 0.032
regulation of mitotic cell cycle GO:0007346 107 0.032
carbohydrate derivative metabolic process GO:1901135 549 0.031
posttranscriptional regulation of gene expression GO:0010608 115 0.031
chromatin organization GO:0006325 242 0.030
secretion by cell GO:0032940 50 0.030
cell cycle g2 m phase transition GO:0044839 39 0.030
ribose phosphate biosynthetic process GO:0046390 50 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.029
purine ribonucleoside metabolic process GO:0046128 380 0.029
single organism membrane organization GO:0044802 275 0.029
er associated ubiquitin dependent protein catabolic process GO:0030433 46 0.029
response to organic cyclic compound GO:0014070 1 0.029
anatomical structure homeostasis GO:0060249 74 0.029
nucleobase containing small molecule metabolic process GO:0055086 491 0.028
proteasomal protein catabolic process GO:0010498 141 0.028
lipoprotein biosynthetic process GO:0042158 40 0.028
meiotic cell cycle process GO:1903046 229 0.028
positive regulation of apoptotic process GO:0043065 3 0.028
rna modification GO:0009451 99 0.028
establishment of protein localization to membrane GO:0090150 99 0.028
ribonucleoside triphosphate metabolic process GO:0009199 356 0.028
atp metabolic process GO:0046034 251 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.027
chromatin silencing at telomere GO:0006348 84 0.027
negative regulation of cell cycle GO:0045786 91 0.027
gene silencing GO:0016458 151 0.027
protein homotetramerization GO:0051289 1 0.027
nucleoside biosynthetic process GO:0009163 38 0.027
cation transport GO:0006812 166 0.027
organonitrogen compound catabolic process GO:1901565 404 0.027
nucleoside triphosphate metabolic process GO:0009141 364 0.027
purine nucleoside monophosphate biosynthetic process GO:0009127 28 0.026
meiotic nuclear division GO:0007126 163 0.026
negative regulation of cell cycle phase transition GO:1901988 59 0.026
cytoskeleton dependent intracellular transport GO:0030705 18 0.026
negative regulation of cell cycle process GO:0010948 86 0.026
oxoacid metabolic process GO:0043436 351 0.025
negative regulation of organelle organization GO:0010639 103 0.025
negative regulation of transcription dna templated GO:0045892 258 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.025
protein to membrane docking GO:0022615 5 0.025
cytoskeleton dependent cytokinesis GO:0061640 65 0.025
signal transduction GO:0007165 208 0.025
maintenance of protein location in cell GO:0032507 50 0.025
nucleoside monophosphate biosynthetic process GO:0009124 33 0.024
meiosis i GO:0007127 92 0.024
protein acylation GO:0043543 66 0.024
microtubule anchoring GO:0034453 25 0.024
glycosyl compound catabolic process GO:1901658 335 0.024
carboxylic acid metabolic process GO:0019752 338 0.024
organophosphate biosynthetic process GO:0090407 182 0.024
lipid biosynthetic process GO:0008610 170 0.024
telomere organization GO:0032200 75 0.024
chromosome segregation GO:0007059 159 0.024
positive regulation of phosphorus metabolic process GO:0010562 147 0.023
sister chromatid segregation GO:0000819 93 0.023
organophosphate catabolic process GO:0046434 338 0.023
organic anion transport GO:0015711 114 0.023
glycosyl compound biosynthetic process GO:1901659 42 0.023
nitrogen compound transport GO:0071705 212 0.023
nucleoside phosphate biosynthetic process GO:1901293 80 0.022
cell wall organization or biogenesis GO:0071554 190 0.022
mitotic cell cycle checkpoint GO:0007093 56 0.022
cytoskeleton organization GO:0007010 230 0.022
growth GO:0040007 157 0.022
external encapsulating structure organization GO:0045229 146 0.022
purine containing compound biosynthetic process GO:0072522 53 0.022
anion transport GO:0006820 145 0.022
multi organism process GO:0051704 233 0.022
intracellular signal transduction GO:0035556 112 0.022
secretion GO:0046903 50 0.022
maintenance of protein location GO:0045185 53 0.021
cytokinesis GO:0000910 92 0.021
lipid localization GO:0010876 60 0.021
lipoprotein metabolic process GO:0042157 40 0.021
organic acid metabolic process GO:0006082 352 0.021
cell cycle phase transition GO:0044770 144 0.021
trna metabolic process GO:0006399 151 0.021
regulation of protein modification process GO:0031399 110 0.021
divalent inorganic cation homeostasis GO:0072507 21 0.020
oxidoreduction coenzyme metabolic process GO:0006733 58 0.020
ribonucleoside triphosphate catabolic process GO:0009203 327 0.020
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.020
negative regulation of rna biosynthetic process GO:1902679 260 0.020
conjugation with cellular fusion GO:0000747 106 0.020
positive regulation of macromolecule metabolic process GO:0010604 394 0.020
organelle localization GO:0051640 128 0.019
regulation of signal transduction GO:0009966 114 0.019
hydrogen transport GO:0006818 61 0.019
regulation of protein metabolic process GO:0051246 237 0.019
ion transport GO:0006811 274 0.019
cellular response to dna damage stimulus GO:0006974 287 0.019
maintenance of location GO:0051235 66 0.019
sexual reproduction GO:0019953 216 0.018
positive regulation of phosphate metabolic process GO:0045937 147 0.018
positive regulation of biosynthetic process GO:0009891 336 0.018
regulation of catabolic process GO:0009894 199 0.018
organic cyclic compound catabolic process GO:1901361 499 0.018
protein complex assembly GO:0006461 302 0.018
positive regulation of cell death GO:0010942 3 0.018
aerobic respiration GO:0009060 55 0.018
cell wall organization GO:0071555 146 0.018
postreplication repair GO:0006301 24 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.017
microtubule based transport GO:0010970 18 0.017
trna modification GO:0006400 75 0.017
dna damage checkpoint GO:0000077 29 0.017
carbohydrate derivative catabolic process GO:1901136 339 0.017
dna templated transcription termination GO:0006353 42 0.017
regulation of cellular component biogenesis GO:0044087 112 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.016
nucleoside catabolic process GO:0009164 335 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
protein processing GO:0016485 64 0.016
regulation of catalytic activity GO:0050790 307 0.016
lipid transport GO:0006869 58 0.016
regulation of protein complex assembly GO:0043254 77 0.016
positive regulation of catalytic activity GO:0043085 178 0.016
ncrna processing GO:0034470 330 0.016
response to oxidative stress GO:0006979 99 0.015
telomere maintenance via recombination GO:0000722 32 0.015
mitochondrial respiratory chain complex iv assembly GO:0033617 18 0.015
cellular homeostasis GO:0019725 138 0.015
dna replication GO:0006260 147 0.015
positive regulation of cytoskeleton organization GO:0051495 39 0.015
purine ribonucleotide catabolic process GO:0009154 327 0.015
pigment biosynthetic process GO:0046148 22 0.015
nucleoside phosphate catabolic process GO:1901292 331 0.015
regulation of cellular localization GO:0060341 50 0.015
negative regulation of mitotic cell cycle GO:0045930 63 0.015
protein dna complex subunit organization GO:0071824 153 0.015
response to external stimulus GO:0009605 158 0.014
purine nucleoside biosynthetic process GO:0042451 31 0.014
peptidyl amino acid modification GO:0018193 116 0.014
regulation of cellular catabolic process GO:0031329 195 0.014
apoptotic process GO:0006915 30 0.014
cellular response to oxidative stress GO:0034599 94 0.014
exocytosis GO:0006887 42 0.014
death GO:0016265 30 0.014
cellular ketone metabolic process GO:0042180 63 0.014
positive regulation of cellular biosynthetic process GO:0031328 336 0.014
regulation of cellular protein metabolic process GO:0032268 232 0.014
positive regulation of programmed cell death GO:0043068 3 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.014
nucleotide catabolic process GO:0009166 330 0.014
regulation of response to stimulus GO:0048583 157 0.013
dna dependent dna replication GO:0006261 115 0.013
phosphorylation GO:0016310 291 0.013
amide transport GO:0042886 22 0.013
purine containing compound catabolic process GO:0072523 332 0.013
reproductive process in single celled organism GO:0022413 145 0.013
nucleoside transport GO:0015858 14 0.013
response to temperature stimulus GO:0009266 74 0.013
hydrogen ion transmembrane transport GO:1902600 49 0.013
protein complex biogenesis GO:0070271 314 0.013
cofactor transport GO:0051181 16 0.012
regulation of dna replication GO:0006275 51 0.012
regulation of intracellular signal transduction GO:1902531 78 0.012
positive regulation of rna biosynthetic process GO:1902680 286 0.012
regulation of translation GO:0006417 89 0.012
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 26 0.012
respiratory chain complex iv assembly GO:0008535 18 0.012
negative regulation of cellular biosynthetic process GO:0031327 312 0.012
purine nucleoside monophosphate metabolic process GO:0009126 262 0.012
carboxylic acid transport GO:0046942 74 0.012
small molecule biosynthetic process GO:0044283 258 0.012
phospholipid biosynthetic process GO:0008654 89 0.012
late endosome to vacuole transport GO:0045324 42 0.012
lipid catabolic process GO:0016042 33 0.012
purine ribonucleoside monophosphate biosynthetic process GO:0009168 28 0.011
cellular component disassembly GO:0022411 86 0.011
purine nucleotide catabolic process GO:0006195 328 0.011
cellular amide metabolic process GO:0043603 59 0.011
positive regulation of catabolic process GO:0009896 135 0.011
histone ubiquitination GO:0016574 17 0.011
single organism developmental process GO:0044767 258 0.011
dna recombination GO:0006310 172 0.011
ribonucleotide biosynthetic process GO:0009260 44 0.011
anion transmembrane transport GO:0098656 79 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.011
cell aging GO:0007569 70 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.011
heme metabolic process GO:0042168 15 0.011
organic acid catabolic process GO:0016054 71 0.011
endocytosis GO:0006897 90 0.011
cellular amine metabolic process GO:0044106 51 0.011
mitotic sister chromatid segregation GO:0000070 85 0.011
spindle organization GO:0007051 37 0.011
rna localization GO:0006403 112 0.011
response to extracellular stimulus GO:0009991 156 0.011
nad metabolic process GO:0019674 25 0.011
regulation of organelle organization GO:0033043 243 0.011
negative regulation of catabolic process GO:0009895 43 0.011
double strand break repair GO:0006302 105 0.011
regulation of mitochondrion organization GO:0010821 20 0.011
mitotic dna integrity checkpoint GO:0044774 18 0.011
g protein coupled receptor signaling pathway GO:0007186 37 0.010
hexose metabolic process GO:0019318 78 0.010
organic acid transport GO:0015849 77 0.010
vacuolar transport GO:0007034 145 0.010
nucleoside triphosphate catabolic process GO:0009143 329 0.010
monocarboxylic acid transport GO:0015718 24 0.010
maintenance of location in cell GO:0051651 58 0.010
nucleus organization GO:0006997 62 0.010
translesion synthesis GO:0019985 16 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.010
amino acid import GO:0043090 2 0.010
rrna metabolic process GO:0016072 244 0.010
positive regulation of protein metabolic process GO:0051247 93 0.010
conjugation GO:0000746 107 0.010
dephosphorylation GO:0016311 127 0.010
regulation of molecular function GO:0065009 320 0.010
inorganic ion transmembrane transport GO:0098660 109 0.010

PEX2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
nervous system disease DOID:863 0 0.013
organ system cancer DOID:0050686 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
cancer DOID:162 0 0.010