Saccharomyces cerevisiae

94 known processes

SLD2 (YKL108W)

Sld2p

(Aliases: DRC1)

SLD2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
double strand break repair via break induced replication GO:0000727 25 0.796
dna replication initiation GO:0006270 48 0.660
double strand break repair GO:0006302 105 0.552
mitotic cell cycle GO:0000278 306 0.455
dna replication GO:0006260 147 0.408
mitotic cell cycle process GO:1903047 294 0.385
recombinational repair GO:0000725 64 0.384
cell cycle phase transition GO:0044770 144 0.359
dna dependent dna replication GO:0006261 115 0.352
dna repair GO:0006281 236 0.345
double strand break repair via homologous recombination GO:0000724 54 0.315
mitotic cell cycle phase transition GO:0044772 141 0.307
pre replicative complex assembly involved in nuclear cell cycle dna replication GO:0006267 20 0.276
dna strand elongation involved in dna replication GO:0006271 26 0.268
nucleotide metabolic process GO:0009117 453 0.266
pre replicative complex assembly GO:0036388 20 0.265
dna unwinding involved in dna replication GO:0006268 13 0.256
dna duplex unwinding GO:0032508 42 0.221
cellular response to dna damage stimulus GO:0006974 287 0.184
negative regulation of mitotic cell cycle GO:0045930 63 0.175
nucleobase containing small molecule metabolic process GO:0055086 491 0.174
protein dna complex subunit organization GO:0071824 153 0.162
carboxylic acid metabolic process GO:0019752 338 0.156
chromatin organization GO:0006325 242 0.150
g1 s transition of mitotic cell cycle GO:0000082 64 0.147
negative regulation of rna biosynthetic process GO:1902679 260 0.141
cell differentiation GO:0030154 161 0.135
dna geometric change GO:0032392 43 0.133
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.129
ncrna processing GO:0034470 330 0.127
dna recombination GO:0006310 172 0.124
single organism catabolic process GO:0044712 619 0.123
nuclear dna replication GO:0033260 27 0.118
cell cycle g1 s phase transition GO:0044843 64 0.117
dna strand elongation GO:0022616 29 0.116
cellular amino acid metabolic process GO:0006520 225 0.115
positive regulation of macromolecule metabolic process GO:0010604 394 0.114
single organism developmental process GO:0044767 258 0.112
regulation of protein metabolic process GO:0051246 237 0.111
pre replicative complex assembly involved in cell cycle dna replication GO:1902299 20 0.111
negative regulation of macromolecule metabolic process GO:0010605 375 0.110
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.108
developmental process involved in reproduction GO:0003006 159 0.108
oxidation reduction process GO:0055114 353 0.106
regulation of cellular protein metabolic process GO:0032268 232 0.106
negative regulation of nucleic acid templated transcription GO:1903507 260 0.097
single organism reproductive process GO:0044702 159 0.096
regulation of dna dependent dna replication initiation GO:0030174 21 0.093
leading strand elongation GO:0006272 9 0.090
regulation of mitotic cell cycle GO:0007346 107 0.087
negative regulation of cellular metabolic process GO:0031324 407 0.085
regulation of protein modification process GO:0031399 110 0.083
carboxylic acid biosynthetic process GO:0046394 152 0.078
single organism signaling GO:0044700 208 0.078
cell cycle checkpoint GO:0000075 82 0.077
small molecule biosynthetic process GO:0044283 258 0.077
cellular developmental process GO:0048869 191 0.076
coenzyme metabolic process GO:0006732 104 0.076
negative regulation of gene expression GO:0010629 312 0.075
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 27 0.075
organophosphate metabolic process GO:0019637 597 0.075
positive regulation of nucleic acid templated transcription GO:1903508 286 0.070
rrna processing GO:0006364 227 0.069
positive regulation of cellular protein metabolic process GO:0032270 89 0.069
positive regulation of rna biosynthetic process GO:1902680 286 0.068
regulation of phosphorylation GO:0042325 86 0.068
regulation of phosphate metabolic process GO:0019220 230 0.068
mitotic cell cycle checkpoint GO:0007093 56 0.066
protein complex assembly GO:0006461 302 0.064
nucleoside phosphate metabolic process GO:0006753 458 0.063
cell cycle dna replication GO:0044786 36 0.060
negative regulation of cellular biosynthetic process GO:0031327 312 0.060
negative regulation of transcription dna templated GO:0045892 258 0.059
nucleotide biosynthetic process GO:0009165 79 0.058
purine containing compound metabolic process GO:0072521 400 0.056
positive regulation of protein metabolic process GO:0051247 93 0.055
protein dna complex assembly GO:0065004 105 0.054
mating type determination GO:0007531 32 0.053
negative regulation of cell cycle process GO:0010948 86 0.051
oxoacid metabolic process GO:0043436 351 0.051
regulation of mitotic cell cycle phase transition GO:1901990 68 0.050
nuclear division GO:0000280 263 0.050
regulation of molecular function GO:0065009 320 0.050
organic cyclic compound catabolic process GO:1901361 499 0.049
sex determination GO:0007530 32 0.049
protein localization to organelle GO:0033365 337 0.047
trna metabolic process GO:0006399 151 0.047
reproductive process GO:0022414 248 0.047
carbohydrate derivative metabolic process GO:1901135 549 0.046
signaling GO:0023052 208 0.046
monosaccharide metabolic process GO:0005996 83 0.046
negative regulation of rna metabolic process GO:0051253 262 0.046
negative regulation of cell cycle phase transition GO:1901988 59 0.046
regulation of phosphorus metabolic process GO:0051174 230 0.045
regulation of cell cycle process GO:0010564 150 0.045
positive regulation of rna metabolic process GO:0051254 294 0.045
organelle fission GO:0048285 272 0.045
chromatin silencing GO:0006342 147 0.044
mitotic dna integrity checkpoint GO:0044774 18 0.044
response to chemical GO:0042221 390 0.043
organic hydroxy compound metabolic process GO:1901615 125 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.042
positive regulation of cellular biosynthetic process GO:0031328 336 0.042
cellular response to chemical stimulus GO:0070887 315 0.041
positive regulation of phosphorylation GO:0042327 33 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.040
regulation of cell cycle GO:0051726 195 0.040
single organism cellular localization GO:1902580 375 0.040
dna integrity checkpoint GO:0031570 41 0.039
gene silencing GO:0016458 151 0.038
nucleobase containing compound catabolic process GO:0034655 479 0.038
cell cycle g2 m phase transition GO:0044839 39 0.037
nucleoside monophosphate metabolic process GO:0009123 267 0.037
negative regulation of biosynthetic process GO:0009890 312 0.036
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.036
chromosome segregation GO:0007059 159 0.036
reproduction of a single celled organism GO:0032505 191 0.035
cell communication GO:0007154 345 0.035
rrna metabolic process GO:0016072 244 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.035
regulation of biological quality GO:0065008 391 0.034
purine nucleoside monophosphate metabolic process GO:0009126 262 0.034
positive regulation of phosphorus metabolic process GO:0010562 147 0.034
cellular nitrogen compound catabolic process GO:0044270 494 0.034
regulation of gene expression epigenetic GO:0040029 147 0.034
organic acid metabolic process GO:0006082 352 0.033
positive regulation of biosynthetic process GO:0009891 336 0.033
carbohydrate derivative biosynthetic process GO:1901137 181 0.032
trna processing GO:0008033 101 0.032
dna damage checkpoint GO:0000077 29 0.032
positive regulation of protein modification process GO:0031401 49 0.032
mitotic nuclear division GO:0007067 131 0.031
protein phosphorylation GO:0006468 197 0.030
heterocycle catabolic process GO:0046700 494 0.030
chromatin silencing at silent mating type cassette GO:0030466 53 0.030
nucleoside phosphate biosynthetic process GO:1901293 80 0.029
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.029
organonitrogen compound catabolic process GO:1901565 404 0.029
regulation of cellular ketone metabolic process GO:0010565 42 0.028
intracellular protein transport GO:0006886 319 0.028
cellular response to organic substance GO:0071310 159 0.028
ribonucleoside monophosphate metabolic process GO:0009161 265 0.028
dephosphorylation GO:0016311 127 0.027
cofactor metabolic process GO:0051186 126 0.026
establishment of protein localization to organelle GO:0072594 278 0.025
nucleotide catabolic process GO:0009166 330 0.025
macromolecule catabolic process GO:0009057 383 0.025
cellular response to nutrient levels GO:0031669 144 0.025
nucleoside monophosphate catabolic process GO:0009125 224 0.025
protein dephosphorylation GO:0006470 40 0.025
maintenance of location GO:0051235 66 0.024
regulation of cellular catabolic process GO:0031329 195 0.024
protein complex biogenesis GO:0070271 314 0.024
monosaccharide catabolic process GO:0046365 28 0.024
single organism carbohydrate metabolic process GO:0044723 237 0.023
energy derivation by oxidation of organic compounds GO:0015980 125 0.023
cellular macromolecule catabolic process GO:0044265 363 0.023
anatomical structure development GO:0048856 160 0.023
negative regulation of gene expression epigenetic GO:0045814 147 0.022
negative regulation of cell cycle GO:0045786 91 0.022
aging GO:0007568 71 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.022
response to organic substance GO:0010033 182 0.022
phosphorylation GO:0016310 291 0.022
nucleoside triphosphate metabolic process GO:0009141 364 0.021
nucleoside phosphate catabolic process GO:1901292 331 0.021
dna conformation change GO:0071103 98 0.021
ribonucleoside triphosphate metabolic process GO:0009199 356 0.020
response to topologically incorrect protein GO:0035966 38 0.020
meiotic nuclear division GO:0007126 163 0.020
regulation of transcription by chromatin organization GO:0034401 19 0.020
carbohydrate metabolic process GO:0005975 252 0.020
positive regulation of molecular function GO:0044093 185 0.020
developmental process GO:0032502 261 0.019
anatomical structure morphogenesis GO:0009653 160 0.019
translation GO:0006412 230 0.019
maintenance of protein location in cell GO:0032507 50 0.019
cell fate commitment GO:0045165 32 0.019
purine nucleotide catabolic process GO:0006195 328 0.018
atp catabolic process GO:0006200 224 0.018
purine nucleoside catabolic process GO:0006152 330 0.018
mitotic dna damage checkpoint GO:0044773 11 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.018
response to nutrient levels GO:0031667 150 0.017
reproductive process in single celled organism GO:0022413 145 0.017
cellular response to extracellular stimulus GO:0031668 150 0.017
amine metabolic process GO:0009308 51 0.017
hexose metabolic process GO:0019318 78 0.017
protein targeting GO:0006605 272 0.017
negative regulation of molecular function GO:0044092 68 0.017
chromatin modification GO:0016568 200 0.016
cellular ketone metabolic process GO:0042180 63 0.016
alcohol biosynthetic process GO:0046165 75 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.016
lagging strand elongation GO:0006273 10 0.016
nucleoside triphosphate catabolic process GO:0009143 329 0.016
atp metabolic process GO:0046034 251 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
establishment of protein localization GO:0045184 367 0.016
ribonucleoside metabolic process GO:0009119 389 0.016
positive regulation of cell cycle GO:0045787 32 0.016
ribonucleoprotein complex subunit organization GO:0071826 152 0.016
regulation of catabolic process GO:0009894 199 0.015
glycosyl compound catabolic process GO:1901658 335 0.015
purine nucleotide metabolic process GO:0006163 376 0.015
response to external stimulus GO:0009605 158 0.015
positive regulation of translation GO:0045727 34 0.015
peptidyl amino acid modification GO:0018193 116 0.015
regulation of protein phosphorylation GO:0001932 75 0.015
positive regulation of gene expression GO:0010628 321 0.015
negative regulation of mitosis GO:0045839 39 0.015
purine nucleoside metabolic process GO:0042278 380 0.015
ribonucleoside monophosphate catabolic process GO:0009158 224 0.015
organophosphate biosynthetic process GO:0090407 182 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
lipid biosynthetic process GO:0008610 170 0.015
meiosis i GO:0007127 92 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.014
meiotic cell cycle process GO:1903046 229 0.014
purine ribonucleotide metabolic process GO:0009150 372 0.014
sister chromatid segregation GO:0000819 93 0.014
nucleoside metabolic process GO:0009116 394 0.014
response to abiotic stimulus GO:0009628 159 0.014
regulation of dna metabolic process GO:0051052 100 0.014
mating type switching GO:0007533 28 0.014
intracellular signal transduction GO:0035556 112 0.014
cellular component morphogenesis GO:0032989 97 0.014
endocytosis GO:0006897 90 0.014
regulation of kinase activity GO:0043549 71 0.014
organelle assembly GO:0070925 118 0.014
establishment of nucleus localization GO:0040023 22 0.014
rna dependent dna replication GO:0006278 25 0.013
regulation of catalytic activity GO:0050790 307 0.013
cellular amino acid catabolic process GO:0009063 48 0.013
cellular amine metabolic process GO:0044106 51 0.013
purine ribonucleotide catabolic process GO:0009154 327 0.013
response to acid chemical GO:0001101 19 0.013
regulation of cell cycle phase transition GO:1901987 70 0.013
generation of precursor metabolites and energy GO:0006091 147 0.013
ribonucleotide catabolic process GO:0009261 327 0.013
single organism carbohydrate catabolic process GO:0044724 73 0.012
postreplication repair GO:0006301 24 0.012
glucose metabolic process GO:0006006 65 0.012
cellular response to external stimulus GO:0071496 150 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.012
trna gene clustering GO:0070058 7 0.012
regulation of cellular component organization GO:0051128 334 0.012
maintenance of location in cell GO:0051651 58 0.012
purine nucleoside monophosphate catabolic process GO:0009128 224 0.012
regulation of chromatin silencing GO:0031935 39 0.012
organonitrogen compound biosynthetic process GO:1901566 314 0.012
positive regulation of transcription dna templated GO:0045893 286 0.012
alcohol metabolic process GO:0006066 112 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.012
regulation of cell communication GO:0010646 124 0.012
translesion synthesis GO:0019985 16 0.011
negative regulation of phosphate metabolic process GO:0045936 49 0.011
regulation of transferase activity GO:0051338 83 0.011
establishment of organelle localization GO:0051656 96 0.011
mitotic sister chromatid segregation GO:0000070 85 0.011
chromatin silencing at telomere GO:0006348 84 0.011
purine containing compound catabolic process GO:0072523 332 0.011
protein transmembrane transport GO:0071806 82 0.011
protein catabolic process GO:0030163 221 0.011
mitotic spindle organization GO:0007052 30 0.011
nucleotide excision repair GO:0006289 50 0.011
intracellular protein transmembrane transport GO:0065002 80 0.011
cell division GO:0051301 205 0.011
ribonucleotide metabolic process GO:0009259 377 0.011
purine nucleoside triphosphate catabolic process GO:0009146 329 0.011
sister chromatid cohesion GO:0007062 49 0.011
response to heat GO:0009408 69 0.011
transmembrane transport GO:0055085 349 0.011
retrograde transport endosome to golgi GO:0042147 33 0.011
purine nucleoside triphosphate metabolic process GO:0009144 356 0.011
response to uv GO:0009411 4 0.011
chromosome condensation GO:0030261 19 0.011
negative regulation of phosphorus metabolic process GO:0010563 49 0.011
dna replication removal of rna primer GO:0043137 5 0.011
double strand break repair via nonhomologous end joining GO:0006303 27 0.011
regulation of translation GO:0006417 89 0.011
posttranscriptional regulation of gene expression GO:0010608 115 0.011
organic acid biosynthetic process GO:0016053 152 0.010
positive regulation of programmed cell death GO:0043068 3 0.010
regulation of nuclear division GO:0051783 103 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.010
cellular response to hypoxia GO:0071456 4 0.010
protein transport GO:0015031 345 0.010
regulation of cellular amine metabolic process GO:0033238 21 0.010

SLD2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011