Saccharomyces cerevisiae

105 known processes

SIR4 (YDR227W)

Sir4p

(Aliases: ASD1,STE9,UTH2)

SIR4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin silencing GO:0006342 147 0.993
negative regulation of biosynthetic process GO:0009890 312 0.992
negative regulation of gene expression epigenetic GO:0045814 147 0.984
negative regulation of macromolecule metabolic process GO:0010605 375 0.984
negative regulation of rna metabolic process GO:0051253 262 0.981
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.981
gene silencing GO:0016458 151 0.969
negative regulation of cellular metabolic process GO:0031324 407 0.966
negative regulation of cellular biosynthetic process GO:0031327 312 0.955
negative regulation of nucleic acid templated transcription GO:1903507 260 0.931
negative regulation of transcription dna templated GO:0045892 258 0.927
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.926
negative regulation of rna biosynthetic process GO:1902679 260 0.922
negative regulation of gene expression GO:0010629 312 0.905
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.879
regulation of gene expression epigenetic GO:0040029 147 0.868
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.848
chromatin silencing at silent mating type cassette GO:0030466 53 0.740
multi organism reproductive process GO:0044703 216 0.467
chromatin modification GO:0016568 200 0.388
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.367
cell aging GO:0007569 70 0.360
chromatin silencing at telomere GO:0006348 84 0.342
reproductive process GO:0022414 248 0.341
aging GO:0007568 71 0.315
regulation of cell communication GO:0010646 124 0.299
recombinational repair GO:0000725 64 0.263
positive regulation of macromolecule metabolic process GO:0010604 394 0.260
regulation of gene silencing GO:0060968 41 0.250
single organism signaling GO:0044700 208 0.239
multi organism process GO:0051704 233 0.229
single organism catabolic process GO:0044712 619 0.211
regulation of chromatin silencing GO:0031935 39 0.205
macromolecule catabolic process GO:0009057 383 0.197
regulation of response to stimulus GO:0048583 157 0.193
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.173
cellular response to chemical stimulus GO:0070887 315 0.172
regulation of cell cycle GO:0051726 195 0.172
chromatin assembly or disassembly GO:0006333 60 0.167
cell communication GO:0007154 345 0.156
regulation of signaling GO:0023051 119 0.140
regulation of cellular component biogenesis GO:0044087 112 0.139
positive regulation of gene expression epigenetic GO:0045815 25 0.134
response to external stimulus GO:0009605 158 0.130
signal transduction GO:0007165 208 0.117
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.116
response to extracellular stimulus GO:0009991 156 0.114
conjugation GO:0000746 107 0.111
cellular response to organic substance GO:0071310 159 0.110
response to nutrient levels GO:0031667 150 0.109
regulation of signal transduction GO:0009966 114 0.107
response to chemical GO:0042221 390 0.099
aromatic compound catabolic process GO:0019439 491 0.095
developmental process GO:0032502 261 0.094
cellular nitrogen compound catabolic process GO:0044270 494 0.092
nucleobase containing small molecule metabolic process GO:0055086 491 0.092
sexual reproduction GO:0019953 216 0.090
nucleotide metabolic process GO:0009117 453 0.085
reproductive process in single celled organism GO:0022413 145 0.083
conjugation with cellular fusion GO:0000747 106 0.082
cellular response to external stimulus GO:0071496 150 0.081
regulation of protein localization GO:0032880 62 0.074
single organism cellular localization GO:1902580 375 0.073
organic cyclic compound catabolic process GO:1901361 499 0.071
single organism reproductive process GO:0044702 159 0.071
cellular response to dna damage stimulus GO:0006974 287 0.070
positive regulation of rna biosynthetic process GO:1902680 286 0.068
regulation of protein modification process GO:0031399 110 0.068
positive regulation of gene expression GO:0010628 321 0.067
positive regulation of rna metabolic process GO:0051254 294 0.066
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.065
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.061
negative regulation of gene silencing GO:0060969 27 0.061
regulation of filamentous growth GO:0010570 38 0.060
chromatin organization GO:0006325 242 0.059
positive regulation of transcription dna templated GO:0045893 286 0.058
carboxylic acid metabolic process GO:0019752 338 0.057
growth GO:0040007 157 0.056
cell differentiation GO:0030154 161 0.054
response to organic substance GO:0010033 182 0.052
positive regulation of nucleic acid templated transcription GO:1903508 286 0.050
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.050
regulation of cellular catabolic process GO:0031329 195 0.049
regulation of protein metabolic process GO:0051246 237 0.049
response to starvation GO:0042594 96 0.048
dna packaging GO:0006323 55 0.048
cellular response to extracellular stimulus GO:0031668 150 0.046
negative regulation of cell cycle phase transition GO:1901988 59 0.045
nucleobase containing compound catabolic process GO:0034655 479 0.045
carbohydrate derivative metabolic process GO:1901135 549 0.043
cellular response to pheromone GO:0071444 88 0.043
cellular macromolecule catabolic process GO:0044265 363 0.043
reproduction of a single celled organism GO:0032505 191 0.042
telomere organization GO:0032200 75 0.042
regulation of biological quality GO:0065008 391 0.041
negative regulation of chromatin silencing GO:0031936 25 0.041
protein complex disassembly GO:0043241 70 0.041
regulation of phosphate metabolic process GO:0019220 230 0.040
mitotic cell cycle process GO:1903047 294 0.040
single organism developmental process GO:0044767 258 0.039
organophosphate metabolic process GO:0019637 597 0.039
regulation of cellular component organization GO:0051128 334 0.039
mitotic cell cycle GO:0000278 306 0.039
regulation of growth GO:0040008 50 0.039
macromolecular complex disassembly GO:0032984 80 0.037
protein complex biogenesis GO:0070271 314 0.037
small molecule catabolic process GO:0044282 88 0.036
telomere maintenance GO:0000723 74 0.036
purine nucleoside catabolic process GO:0006152 330 0.035
positive regulation of cellular biosynthetic process GO:0031328 336 0.035
establishment or maintenance of cell polarity GO:0007163 96 0.034
double strand break repair GO:0006302 105 0.034
regulation of catabolic process GO:0009894 199 0.033
response to oxygen containing compound GO:1901700 61 0.032
protein import into nucleus GO:0006606 55 0.032
regulation of protein complex assembly GO:0043254 77 0.032
positive regulation of cellular protein metabolic process GO:0032270 89 0.031
carbohydrate metabolic process GO:0005975 252 0.031
positive regulation of catabolic process GO:0009896 135 0.031
regulation of chromatin modification GO:1903308 23 0.030
positive regulation of cellular catabolic process GO:0031331 128 0.030
regulation of response to external stimulus GO:0032101 20 0.030
multi organism cellular process GO:0044764 120 0.030
cellular response to endogenous stimulus GO:0071495 22 0.030
purine containing compound metabolic process GO:0072521 400 0.029
dna conformation change GO:0071103 98 0.029
ribonucleoside metabolic process GO:0009119 389 0.029
nuclear transport GO:0051169 165 0.029
mrna catabolic process GO:0006402 93 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.028
regulation of transport GO:0051049 85 0.027
organonitrogen compound catabolic process GO:1901565 404 0.027
purine ribonucleoside metabolic process GO:0046128 380 0.027
regulation of localization GO:0032879 127 0.027
nitrogen compound transport GO:0071705 212 0.027
cytoskeleton organization GO:0007010 230 0.027
ribonucleoside catabolic process GO:0042454 332 0.027
carbohydrate derivative catabolic process GO:1901136 339 0.026
autophagy GO:0006914 106 0.025
chromatin remodeling GO:0006338 80 0.025
regulation of developmental process GO:0050793 30 0.025
rna transport GO:0050658 92 0.024
mrna metabolic process GO:0016071 269 0.024
response to abiotic stimulus GO:0009628 159 0.024
positive regulation of response to stimulus GO:0048584 37 0.024
purine ribonucleoside catabolic process GO:0046130 330 0.024
nucleoside phosphate metabolic process GO:0006753 458 0.023
purine nucleotide catabolic process GO:0006195 328 0.023
regulation of cellular response to stress GO:0080135 50 0.023
replicative cell aging GO:0001302 46 0.023
heterocycle catabolic process GO:0046700 494 0.023
telomere maintenance via telomerase GO:0007004 21 0.022
telomere maintenance via telomere lengthening GO:0010833 22 0.022
signaling GO:0023052 208 0.022
regulation of dna templated transcription elongation GO:0032784 44 0.022
cellular component disassembly GO:0022411 86 0.022
protein localization to nucleus GO:0034504 74 0.022
nuclear transcribed mrna catabolic process GO:0000956 89 0.021
purine containing compound catabolic process GO:0072523 332 0.021
cellular carbohydrate metabolic process GO:0044262 135 0.021
organophosphate catabolic process GO:0046434 338 0.021
response to pheromone GO:0019236 92 0.021
nucleoside metabolic process GO:0009116 394 0.021
oxoacid metabolic process GO:0043436 351 0.021
organic acid metabolic process GO:0006082 352 0.021
dna repair GO:0006281 236 0.020
amine metabolic process GO:0009308 51 0.020
ribonucleotide metabolic process GO:0009259 377 0.020
regulation of catalytic activity GO:0050790 307 0.020
regulation of reproductive process GO:2000241 24 0.020
nucleocytoplasmic transport GO:0006913 163 0.019
protein complex assembly GO:0006461 302 0.019
regulation of hydrolase activity GO:0051336 133 0.019
developmental process involved in reproduction GO:0003006 159 0.019
regulation of cellular protein metabolic process GO:0032268 232 0.018
nucleotide catabolic process GO:0009166 330 0.018
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 38 0.018
regulation of cellular amino acid metabolic process GO:0006521 16 0.018
cellular protein complex disassembly GO:0043624 42 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.017
purine ribonucleotide metabolic process GO:0009150 372 0.017
dna templated transcription elongation GO:0006354 91 0.017
negative regulation of cellular component organization GO:0051129 109 0.016
regulation of mitotic cell cycle GO:0007346 107 0.016
filamentous growth GO:0030447 124 0.016
regulation of growth of unicellular organism as a thread of attached cells GO:0070784 31 0.016
histone acetylation GO:0016573 51 0.016
negative regulation of cell communication GO:0010648 33 0.016
single organism nuclear import GO:1902593 56 0.016
nucleoside monophosphate catabolic process GO:0009125 224 0.015
response to oxidative stress GO:0006979 99 0.015
cellular developmental process GO:0048869 191 0.015
cytokinesis GO:0000910 92 0.015
regulation of organelle organization GO:0033043 243 0.015
ribonucleoside triphosphate catabolic process GO:0009203 327 0.015
nucleoside triphosphate metabolic process GO:0009141 364 0.015
response to organic cyclic compound GO:0014070 1 0.015
purine ribonucleotide catabolic process GO:0009154 327 0.015
cellular response to starvation GO:0009267 90 0.015
regulation of molecular function GO:0065009 320 0.014
regulation of cell cycle process GO:0010564 150 0.014
invasive growth in response to glucose limitation GO:0001403 61 0.014
glycosyl compound catabolic process GO:1901658 335 0.014
nucleoside triphosphate catabolic process GO:0009143 329 0.014
protein localization to chromosome GO:0034502 28 0.014
negative regulation of intracellular signal transduction GO:1902532 27 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.014
positive regulation of nucleotide catabolic process GO:0030813 97 0.014
ribose phosphate metabolic process GO:0019693 384 0.013
establishment of protein localization to organelle GO:0072594 278 0.013
positive regulation of nucleoside metabolic process GO:0045979 97 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.013
organelle fission GO:0048285 272 0.013
cell division GO:0051301 205 0.013
chromatin assembly GO:0031497 35 0.013
response to pheromone involved in conjugation with cellular fusion GO:0000749 74 0.013
positive regulation of secretion by cell GO:1903532 2 0.013
monocarboxylic acid metabolic process GO:0032787 122 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.012
cell surface receptor signaling pathway GO:0007166 38 0.012
cellular response to nutrient levels GO:0031669 144 0.012
regulation of cellular amine metabolic process GO:0033238 21 0.012
protein import GO:0017038 122 0.012
positive regulation of cell communication GO:0010647 28 0.012
nuclear import GO:0051170 57 0.012
positive regulation of hydrolase activity GO:0051345 112 0.012
cellular component morphogenesis GO:0032989 97 0.012
death GO:0016265 30 0.012
histone exchange GO:0043486 18 0.011
negative regulation of chromosome organization GO:2001251 39 0.011
establishment of rna localization GO:0051236 92 0.011
regulation of dna templated transcription in response to stress GO:0043620 51 0.011
sporulation resulting in formation of a cellular spore GO:0030435 129 0.011
mitotic cytokinesis site selection GO:1902408 35 0.011
regulation of chromosome organization GO:0033044 66 0.011
regulation of response to extracellular stimulus GO:0032104 20 0.011
filamentous growth of a population of unicellular organisms GO:0044182 109 0.011
ribonucleotide catabolic process GO:0009261 327 0.011
intracellular protein transport GO:0006886 319 0.011
regulation of nucleoside metabolic process GO:0009118 106 0.011
mitochondrion organization GO:0007005 261 0.011
double strand break repair via nonhomologous end joining GO:0006303 27 0.010
protein phosphorylation GO:0006468 197 0.010
regulation of cellular ketone metabolic process GO:0010565 42 0.010
positive regulation of protein modification process GO:0031401 49 0.010
positive regulation of organelle organization GO:0010638 85 0.010
regulation of dna metabolic process GO:0051052 100 0.010
negative regulation of chromatin modification GO:1903309 9 0.010

SIR4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org