Saccharomyces cerevisiae

22 known processes

RPN12 (YFR052W)

Rpn12p

(Aliases: NIN1)

RPN12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis GO:0006508 268 0.992
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.967
modification dependent macromolecule catabolic process GO:0043632 203 0.965
ubiquitin dependent protein catabolic process GO:0006511 181 0.934
modification dependent protein catabolic process GO:0019941 181 0.928
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.911
cellular macromolecule catabolic process GO:0044265 363 0.897
macromolecule catabolic process GO:0009057 383 0.839
cellular response to dna damage stimulus GO:0006974 287 0.792
cellular protein catabolic process GO:0044257 213 0.768
proteasomal protein catabolic process GO:0010498 141 0.623
mitotic cell cycle process GO:1903047 294 0.471
Fly
mitotic cell cycle GO:0000278 306 0.447
Fly
protein catabolic process GO:0030163 221 0.385
positive regulation of macromolecule metabolic process GO:0010604 394 0.352
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.325
nuclear division GO:0000280 263 0.317
cellular protein complex assembly GO:0043623 209 0.316
organic cyclic compound catabolic process GO:1901361 499 0.307
positive regulation of biosynthetic process GO:0009891 336 0.298
organelle fission GO:0048285 272 0.266
positive regulation of nucleic acid templated transcription GO:1903508 286 0.254
protein complex biogenesis GO:0070271 314 0.244
microtubule cytoskeleton organization GO:0000226 109 0.229
Fly
proteasome assembly GO:0043248 31 0.220
positive regulation of rna biosynthetic process GO:1902680 286 0.217
positive regulation of transcription dna templated GO:0045893 286 0.190
heterocycle catabolic process GO:0046700 494 0.187
nucleobase containing compound catabolic process GO:0034655 479 0.187
positive regulation of cellular biosynthetic process GO:0031328 336 0.176
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.164
positive regulation of rna metabolic process GO:0051254 294 0.162
regulation of cellular component organization GO:0051128 334 0.157
cellular nitrogen compound catabolic process GO:0044270 494 0.149
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.143
regulation of cell cycle GO:0051726 195 0.140
regulation of biological quality GO:0065008 391 0.136
aromatic compound catabolic process GO:0019439 491 0.135
protein modification by small protein conjugation or removal GO:0070647 172 0.135
spindle organization GO:0007051 37 0.130
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.127
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.116
cell differentiation GO:0030154 161 0.114
Fly
regulation of cell cycle process GO:0010564 150 0.112
single organism carbohydrate metabolic process GO:0044723 237 0.112
microtubule based process GO:0007017 117 0.109
Fly
chromosome segregation GO:0007059 159 0.109
dna repair GO:0006281 236 0.106
single organism catabolic process GO:0044712 619 0.105
positive regulation of gene expression GO:0010628 321 0.100
protein complex assembly GO:0006461 302 0.096
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.081
regulation of proteolysis GO:0030162 44 0.080
regulation of protein metabolic process GO:0051246 237 0.079
regulation of cellular localization GO:0060341 50 0.079
carbohydrate metabolic process GO:0005975 252 0.077
regulation of cellular protein metabolic process GO:0032268 232 0.074
negative regulation of cellular metabolic process GO:0031324 407 0.072
meiotic cell cycle GO:0051321 272 0.071
meiotic nuclear division GO:0007126 163 0.070
negative regulation of gene expression GO:0010629 312 0.069
Worm
mitotic nuclear division GO:0007067 131 0.068
developmental process GO:0032502 261 0.065
Worm Fly
cellular developmental process GO:0048869 191 0.065
Fly
regulation of catabolic process GO:0009894 199 0.063
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.063
regulation of catalytic activity GO:0050790 307 0.054
regulation of cell division GO:0051302 113 0.054
positive regulation of molecular function GO:0044093 185 0.054
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.053
cell cycle phase transition GO:0044770 144 0.052
organelle localization GO:0051640 128 0.052
programmed cell death GO:0012501 30 0.051
double strand break repair GO:0006302 105 0.051
rna catabolic process GO:0006401 118 0.050
er associated ubiquitin dependent protein catabolic process GO:0030433 46 0.050
nuclear transport GO:0051169 165 0.049
cellular carbohydrate metabolic process GO:0044262 135 0.048
dna templated transcription initiation GO:0006352 71 0.047
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.046
regulation of localization GO:0032879 127 0.046
cell death GO:0008219 30 0.044
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.044
sister chromatid segregation GO:0000819 93 0.042
regulation of protein catabolic process GO:0042176 40 0.042
response to chemical GO:0042221 390 0.041
negative regulation of cellular biosynthetic process GO:0031327 312 0.040
regulation of protein complex assembly GO:0043254 77 0.040
regulation of cellular catabolic process GO:0031329 195 0.039
apoptotic process GO:0006915 30 0.038
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.038
carbohydrate derivative metabolic process GO:1901135 549 0.038
mitotic cell cycle phase transition GO:0044772 141 0.037
protein modification by small protein conjugation GO:0032446 144 0.037
single organism developmental process GO:0044767 258 0.037
Worm Fly
cell division GO:0051301 205 0.036
chromatin organization GO:0006325 242 0.036
reproduction of a single celled organism GO:0032505 191 0.036
cytoskeleton organization GO:0007010 230 0.036
Fly
protein dna complex assembly GO:0065004 105 0.036
phosphorylation GO:0016310 291 0.035
positive regulation of protein metabolic process GO:0051247 93 0.035
positive regulation of cellular component organization GO:0051130 116 0.034
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.034
nucleocytoplasmic transport GO:0006913 163 0.033
rrna metabolic process GO:0016072 244 0.033
negative regulation of rna biosynthetic process GO:1902679 260 0.031
regulation of proteasomal protein catabolic process GO:0061136 34 0.030
cell communication GO:0007154 345 0.029
response to oxidative stress GO:0006979 99 0.029
regulation of molecular function GO:0065009 320 0.029
regulation of mitotic cell cycle GO:0007346 107 0.028
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 35 0.027
positive regulation of cellular protein metabolic process GO:0032270 89 0.027
negative regulation of nucleic acid templated transcription GO:1903507 260 0.026
cellular response to chemical stimulus GO:0070887 315 0.026
regulation of nuclear division GO:0051783 103 0.025
reproductive process in single celled organism GO:0022413 145 0.025
regulation of organelle organization GO:0033043 243 0.024
regulation of protein localization GO:0032880 62 0.024
protein localization to organelle GO:0033365 337 0.023
nuclear export GO:0051168 124 0.023
regulation of protein modification process GO:0031399 110 0.023
chromatin modification GO:0016568 200 0.023
posttranscriptional regulation of gene expression GO:0010608 115 0.022
Worm
positive regulation of catalytic activity GO:0043085 178 0.022
organophosphate metabolic process GO:0019637 597 0.022
establishment of rna localization GO:0051236 92 0.021
anatomical structure development GO:0048856 160 0.020
Worm Fly
negative regulation of biosynthetic process GO:0009890 312 0.020
mitotic sister chromatid segregation GO:0000070 85 0.020
positive regulation of catabolic process GO:0009896 135 0.020
double strand break repair via homologous recombination GO:0000724 54 0.019
positive regulation of cellular catabolic process GO:0031331 128 0.019
death GO:0016265 30 0.019
protein ubiquitination GO:0016567 118 0.019
single organism signaling GO:0044700 208 0.019
meiotic cell cycle process GO:1903046 229 0.019
regulation of transport GO:0051049 85 0.018
negative regulation of macromolecule metabolic process GO:0010605 375 0.018
Worm
cell growth GO:0016049 89 0.016
rna localization GO:0006403 112 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.015
growth GO:0040007 157 0.015
negative regulation of transcription dna templated GO:0045892 258 0.014
negative regulation of rna metabolic process GO:0051253 262 0.014
regulation of cellular protein catabolic process GO:1903362 36 0.014
ncrna catabolic process GO:0034661 33 0.014
response to organic substance GO:0010033 182 0.013
positive regulation of protein complex assembly GO:0031334 39 0.013
dna conformation change GO:0071103 98 0.013
oxidation reduction process GO:0055114 353 0.013
nucleobase containing compound transport GO:0015931 124 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.013
homeostatic process GO:0042592 227 0.013
intracellular signal transduction GO:0035556 112 0.012
signaling GO:0023052 208 0.012
regulation of mitosis GO:0007088 65 0.012
mitotic spindle elongation GO:0000022 14 0.012
Fly
rrna catabolic process GO:0016075 31 0.011
reproductive process GO:0022414 248 0.011
single organism membrane organization GO:0044802 275 0.011
regulation of dna metabolic process GO:0051052 100 0.011
developmental process involved in reproduction GO:0003006 159 0.010
cell aging GO:0007569 70 0.010
proteasome regulatory particle assembly GO:0070682 11 0.010
response to inorganic substance GO:0010035 47 0.010

RPN12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org