Saccharomyces cerevisiae

117 known processes

EAF3 (YPR023C)

Eaf3p

EAF3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nucleic acid templated transcription GO:1903507 260 0.879
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.848
histone acetylation GO:0016573 51 0.828
negative regulation of rna biosynthetic process GO:1902679 260 0.793
negative regulation of transcription dna templated GO:0045892 258 0.772
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.702
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.679
chromatin modification GO:0016568 200 0.677
cellular response to dna damage stimulus GO:0006974 287 0.629
dna repair GO:0006281 236 0.577
negative regulation of cellular biosynthetic process GO:0031327 312 0.544
negative regulation of cellular metabolic process GO:0031324 407 0.535
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.526
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.475
negative regulation of rna metabolic process GO:0051253 262 0.463
peptidyl amino acid modification GO:0018193 116 0.439
peptidyl lysine modification GO:0018205 77 0.389
negative regulation of biosynthetic process GO:0009890 312 0.296
negative regulation of macromolecule metabolic process GO:0010605 375 0.292
intracellular signal transduction GO:0035556 112 0.251
organic acid biosynthetic process GO:0016053 152 0.208
internal protein amino acid acetylation GO:0006475 52 0.187
regulation of response to stress GO:0080134 57 0.184
peptidyl lysine acetylation GO:0018394 52 0.182
lipid biosynthetic process GO:0008610 170 0.179
establishment of protein localization to organelle GO:0072594 278 0.171
anion transport GO:0006820 145 0.166
chromatin organization GO:0006325 242 0.160
positive regulation of gene expression epigenetic GO:0045815 25 0.156
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.155
protein acetylation GO:0006473 59 0.151
covalent chromatin modification GO:0016569 119 0.147
negative regulation of chromatin silencing GO:0031936 25 0.143
histone modification GO:0016570 119 0.140
negative regulation of gene expression GO:0010629 312 0.135
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 33 0.132
negative regulation of gene silencing GO:0060969 27 0.127
cell communication GO:0007154 345 0.120
growth GO:0040007 157 0.115
response to oxygen containing compound GO:1901700 61 0.112
cell wall biogenesis GO:0042546 93 0.105
positive regulation of biosynthetic process GO:0009891 336 0.104
positive regulation of transport GO:0051050 32 0.102
positive regulation of transcription dna templated GO:0045893 286 0.100
negative regulation of chromatin silencing at telomere GO:0031939 15 0.099
meiosis i GO:0007127 92 0.095
regulation of chromatin silencing GO:0031935 39 0.092
signaling GO:0023052 208 0.091
internal peptidyl lysine acetylation GO:0018393 52 0.088
organonitrogen compound biosynthetic process GO:1901566 314 0.087
carboxylic acid biosynthetic process GO:0046394 152 0.087
cellular protein catabolic process GO:0044257 213 0.085
lipid metabolic process GO:0006629 269 0.082
meiotic cell cycle process GO:1903046 229 0.077
alcohol metabolic process GO:0006066 112 0.074
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.073
cellular response to extracellular stimulus GO:0031668 150 0.073
regulation of transport GO:0051049 85 0.072
single organism signaling GO:0044700 208 0.071
phytosteroid metabolic process GO:0016128 31 0.069
regulation of transcription from rna polymerase i promoter GO:0006356 36 0.069
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.068
double strand break repair GO:0006302 105 0.067
cellular amino acid biosynthetic process GO:0008652 118 0.067
response to chemical GO:0042221 390 0.066
protein ubiquitination GO:0016567 118 0.065
modification dependent protein catabolic process GO:0019941 181 0.064
proteolysis GO:0006508 268 0.063
single organism catabolic process GO:0044712 619 0.062
protein acylation GO:0043543 66 0.061
regulation of response to external stimulus GO:0032101 20 0.060
response to nutrient levels GO:0031667 150 0.058
protein localization to organelle GO:0033365 337 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.057
monocarboxylic acid metabolic process GO:0032787 122 0.056
sporulation resulting in formation of a cellular spore GO:0030435 129 0.055
positive regulation of transcription from rna polymerase ii promoter in response to heat stress GO:0061408 12 0.055
regulation of localization GO:0032879 127 0.053
cellular ketone metabolic process GO:0042180 63 0.052
regulation of cellular localization GO:0060341 50 0.052
intracellular protein transport GO:0006886 319 0.051
nitrogen compound transport GO:0071705 212 0.050
cell aging GO:0007569 70 0.050
response to abiotic stimulus GO:0009628 159 0.049
chromatin silencing GO:0006342 147 0.048
Fly
cellular lipid metabolic process GO:0044255 229 0.048
carboxylic acid metabolic process GO:0019752 338 0.048
dna replication initiation GO:0006270 48 0.048
small molecule biosynthetic process GO:0044283 258 0.048
developmental process GO:0032502 261 0.047
regulation of cellular response to stress GO:0080135 50 0.046
protein modification by small protein conjugation GO:0032446 144 0.046
positive regulation of cell communication GO:0010647 28 0.044
protein transport GO:0015031 345 0.044
signal transduction GO:0007165 208 0.044
regulation of intracellular signal transduction GO:1902531 78 0.044
response to heat GO:0009408 69 0.044
positive regulation of cellular biosynthetic process GO:0031328 336 0.042
steroid biosynthetic process GO:0006694 35 0.042
mitochondrion organization GO:0007005 261 0.042
single organism cellular localization GO:1902580 375 0.042
negative regulation of cellular component organization GO:0051129 109 0.042
fatty acid metabolic process GO:0006631 51 0.041
regulation of response to extracellular stimulus GO:0032104 20 0.041
sexual sporulation GO:0034293 113 0.041
proteasomal protein catabolic process GO:0010498 141 0.040
protein catabolic process GO:0030163 221 0.040
cellular response to oxygen containing compound GO:1901701 43 0.039
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.039
cellular response to oxidative stress GO:0034599 94 0.039
response to external stimulus GO:0009605 158 0.038
response to organic substance GO:0010033 182 0.037
glycerolipid metabolic process GO:0046486 108 0.037
regulation of chromatin silencing at telomere GO:0031938 27 0.037
macromolecule catabolic process GO:0009057 383 0.037
regulation of gene silencing GO:0060968 41 0.037
alcohol biosynthetic process GO:0046165 75 0.036
positive regulation of cell death GO:0010942 3 0.035
positive regulation of nucleic acid templated transcription GO:1903508 286 0.035
cellular polysaccharide metabolic process GO:0044264 55 0.035
response to reactive oxygen species GO:0000302 22 0.035
positive regulation of catabolic process GO:0009896 135 0.035
regulation of signal transduction GO:0009966 114 0.034
organic hydroxy compound metabolic process GO:1901615 125 0.034
replicative cell aging GO:0001302 46 0.034
negative regulation of intracellular signal transduction GO:1902532 27 0.033
sporulation GO:0043934 132 0.033
cellular response to heat GO:0034605 53 0.032
regulation of protein localization GO:0032880 62 0.032
macroautophagy GO:0016236 55 0.032
chromatin silencing at telomere GO:0006348 84 0.032
positive regulation of programmed cell death GO:0043068 3 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.031
dna templated transcription elongation GO:0006354 91 0.031
cellular response to chemical stimulus GO:0070887 315 0.031
response to organic cyclic compound GO:0014070 1 0.030
death GO:0016265 30 0.030
response to extracellular stimulus GO:0009991 156 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.029
establishment of protein localization GO:0045184 367 0.029
cellular alcohol biosynthetic process GO:0044108 29 0.029
glycerophospholipid metabolic process GO:0006650 98 0.028
sterol biosynthetic process GO:0016126 35 0.028
protein modification by small protein conjugation or removal GO:0070647 172 0.028
regulation of cellular component organization GO:0051128 334 0.027
positive regulation of response to stimulus GO:0048584 37 0.027
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.027
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.027
regulation of response to nutrient levels GO:0032107 20 0.026
fungal type cell wall biogenesis GO:0009272 80 0.026
positive regulation of cellular catabolic process GO:0031331 128 0.026
carboxylic acid catabolic process GO:0046395 71 0.026
cellular response to starvation GO:0009267 90 0.025
ncrna processing GO:0034470 330 0.025
sulfur compound biosynthetic process GO:0044272 53 0.025
organic acid metabolic process GO:0006082 352 0.025
regulation of mapk cascade GO:0043408 22 0.024
regulation of cellular catabolic process GO:0031329 195 0.024
positive regulation of organelle organization GO:0010638 85 0.024
organic hydroxy compound biosynthetic process GO:1901617 81 0.024
regulation of cell communication GO:0010646 124 0.024
phospholipid metabolic process GO:0006644 125 0.024
positive regulation of phosphorus metabolic process GO:0010562 147 0.023
regulation of response to stimulus GO:0048583 157 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.023
protein import into nucleus GO:0006606 55 0.023
response to oxidative stress GO:0006979 99 0.022
regulation of signaling GO:0023051 119 0.022
lipid catabolic process GO:0016042 33 0.022
regulation of dna templated transcription in response to stress GO:0043620 51 0.022
carbohydrate derivative metabolic process GO:1901135 549 0.021
small molecule catabolic process GO:0044282 88 0.021
protein complex biogenesis GO:0070271 314 0.021
cellular amino acid metabolic process GO:0006520 225 0.021
cell development GO:0048468 107 0.021
transfer rna gene mediated silencing GO:0061587 14 0.021
regulation of intracellular protein transport GO:0033157 13 0.021
cellular response to external stimulus GO:0071496 150 0.020
positive regulation of rna metabolic process GO:0051254 294 0.020
anatomical structure development GO:0048856 160 0.020
regulation of cell cycle process GO:0010564 150 0.020
organelle localization GO:0051640 128 0.020
regulation of macroautophagy GO:0016241 15 0.020
cellular response to organic substance GO:0071310 159 0.020
double strand break repair via nonhomologous end joining GO:0006303 27 0.020
response to temperature stimulus GO:0009266 74 0.019
negative regulation of cellular response to alkaline ph by negative regulation of transcription from rna polymerase ii promoter GO:1900463 1 0.019
negative regulation of steroid biosynthetic process GO:0010894 1 0.019
gene silencing GO:0016458 151 0.019
Fly
ergosterol biosynthetic process GO:0006696 29 0.018
anatomical structure morphogenesis GO:0009653 160 0.018
negative regulation of organelle organization GO:0010639 103 0.018
ubiquitin dependent protein catabolic process GO:0006511 181 0.018
response to starvation GO:0042594 96 0.018
anatomical structure formation involved in morphogenesis GO:0048646 136 0.018
positive regulation of gene expression GO:0010628 321 0.017
amide transport GO:0042886 22 0.017
response to nutrient GO:0007584 52 0.017
transcription from rna polymerase i promoter GO:0006360 63 0.017
sterol metabolic process GO:0016125 47 0.017
negative regulation of cell cycle GO:0045786 91 0.017
positive regulation of cytoplasmic transport GO:1903651 4 0.017
protein deacetylation GO:0006476 26 0.017
positive regulation of transcription from rna polymerase ii promoter in response to ethanol GO:0061410 3 0.017
developmental process involved in reproduction GO:0003006 159 0.017
protein complex assembly GO:0006461 302 0.016
carbohydrate metabolic process GO:0005975 252 0.016
regulation of cellular ketone metabolic process GO:0010565 42 0.016
modification dependent macromolecule catabolic process GO:0043632 203 0.016
chromatin silencing at rdna GO:0000183 32 0.016
mapk cascade GO:0000165 30 0.016
positive regulation of signal transduction GO:0009967 20 0.016
positive regulation of secretion GO:0051047 2 0.015
cellular macromolecule catabolic process GO:0044265 363 0.015
regulation of transcription factor import into nucleus GO:0042990 4 0.015
regulation of autophagy GO:0010506 18 0.015
response to hydrogen peroxide GO:0042542 12 0.015
peroxisome organization GO:0007031 68 0.015
fatty acid beta oxidation GO:0006635 12 0.015
cell cycle phase transition GO:0044770 144 0.015
positive regulation of rna biosynthetic process GO:1902680 286 0.015
regulation of protein targeting GO:1903533 10 0.015
fatty acid catabolic process GO:0009062 17 0.014
negative regulation of response to salt stress GO:1901001 2 0.014
positive regulation of fatty acid beta oxidation by positive regulation of transcription from rna polymerase ii promoter GO:0097235 1 0.014
ergosterol metabolic process GO:0008204 31 0.014
aging GO:0007568 71 0.014
filamentous growth GO:0030447 124 0.014
regulation of sodium ion transport GO:0002028 1 0.013
protein import GO:0017038 122 0.013
programmed cell death GO:0012501 30 0.013
positive regulation of transcription from rna polymerase ii promoter in response to salt stress GO:0036251 4 0.013
positive regulation of transcription from rna polymerase ii promoter by oleic acid GO:0061429 4 0.013
ion homeostasis GO:0050801 118 0.013
signal transduction by phosphorylation GO:0023014 31 0.013
stress activated protein kinase signaling cascade GO:0031098 4 0.013
glycerophospholipid biosynthetic process GO:0046474 68 0.012
non recombinational repair GO:0000726 33 0.012
single organism nuclear import GO:1902593 56 0.012
cellular developmental process GO:0048869 191 0.012
cell division GO:0051301 205 0.012
cell death GO:0008219 30 0.012
response to endoplasmic reticulum stress GO:0034976 23 0.012
regulation of mitochondrion organization GO:0010821 20 0.012
regulation of potassium ion concentration by positive regulation of transcription from rna polymerase ii promoter GO:0097301 1 0.012
regulation of cell cycle phase transition GO:1901987 70 0.012
posttranscriptional regulation of gene expression GO:0010608 115 0.012
positive regulation of transcription from rna polymerase ii promoter in response to increased salt GO:0061404 4 0.012
cation transport GO:0006812 166 0.012
acetate biosynthetic process GO:0019413 4 0.012
positive regulation of secretion by cell GO:1903532 2 0.012
regulation of protein transport GO:0051223 17 0.012
mitotic cell cycle checkpoint GO:0007093 56 0.012
carbon catabolite regulation of transcription GO:0045990 39 0.012
establishment of organelle localization GO:0051656 96 0.011
negative regulation of cellular response to alkaline ph GO:1900068 1 0.011
positive regulation of transcription by oleic acid GO:0061421 4 0.011
protein dna complex assembly GO:0065004 105 0.011
chromatin remodeling GO:0006338 80 0.011
Fly
peptide metabolic process GO:0006518 28 0.011
regulation of cellular amine metabolic process GO:0033238 21 0.011
response to uv GO:0009411 4 0.011
organelle fission GO:0048285 272 0.011
filamentous growth of a population of unicellular organisms GO:0044182 109 0.011
glutathione metabolic process GO:0006749 16 0.011
positive regulation of signaling GO:0023056 20 0.011
positive regulation of sodium ion transport by positive regulation of transcription from rna polymerase ii promoter GO:0061423 1 0.011
fungal type cell wall organization or biogenesis GO:0071852 169 0.011
negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from rna polymerase ii promoter GO:1900464 2 0.011
regulation of organelle organization GO:0033043 243 0.011
cellular response to zinc ion starvation GO:0034224 3 0.011
negative regulation of carbohydrate metabolic process GO:0045912 17 0.011
positive regulation of peroxisome organization by positive regulation of transcription from rna polymerase ii promoter GO:0061424 1 0.011
regulation of protein localization to nucleus GO:1900180 16 0.011
regulation of translation GO:0006417 89 0.010
negative regulation of cellular carbohydrate metabolic process GO:0010677 17 0.010
single organism developmental process GO:0044767 258 0.010
transmembrane transport GO:0055085 349 0.010
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 34 0.010
polyol metabolic process GO:0019751 22 0.010
nuclear import GO:0051170 57 0.010
single organism reproductive process GO:0044702 159 0.010
regulation of lipid catabolic process GO:0050994 4 0.010
regulation of transcription from rna polymerase ii promoter by calcium mediated signaling GO:1900621 1 0.010
positive regulation of transcription from rna polymerase ii promoter in response to calcium ion GO:0061400 1 0.010
positive regulation of lipid catabolic process GO:0050996 4 0.010

EAF3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.022
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
disease of anatomical entity DOID:7 0 0.019