Saccharomyces cerevisiae

117 known processes

EAF3 (YPR023C)

Eaf3p

EAF3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nucleic acid templated transcription GO:1903507 260 0.879
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.848
histone acetylation GO:0016573 51 0.828
negative regulation of rna biosynthetic process GO:1902679 260 0.793
negative regulation of transcription dna templated GO:0045892 258 0.772
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.702
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.679
chromatin modification GO:0016568 200 0.677
cellular response to dna damage stimulus GO:0006974 287 0.629
dna repair GO:0006281 236 0.577
negative regulation of cellular biosynthetic process GO:0031327 312 0.544
negative regulation of cellular metabolic process GO:0031324 407 0.535
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.526
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.475
negative regulation of rna metabolic process GO:0051253 262 0.463
peptidyl amino acid modification GO:0018193 116 0.439
peptidyl lysine modification GO:0018205 77 0.389
negative regulation of biosynthetic process GO:0009890 312 0.296
negative regulation of macromolecule metabolic process GO:0010605 375 0.292
intracellular signal transduction GO:0035556 112 0.251
organic acid biosynthetic process GO:0016053 152 0.208
internal protein amino acid acetylation GO:0006475 52 0.187
regulation of response to stress GO:0080134 57 0.184
peptidyl lysine acetylation GO:0018394 52 0.182
lipid biosynthetic process GO:0008610 170 0.179
establishment of protein localization to organelle GO:0072594 278 0.171
anion transport GO:0006820 145 0.166
chromatin organization GO:0006325 242 0.160
positive regulation of gene expression epigenetic GO:0045815 25 0.156
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.155
protein acetylation GO:0006473 59 0.151
covalent chromatin modification GO:0016569 119 0.147
negative regulation of chromatin silencing GO:0031936 25 0.143
histone modification GO:0016570 119 0.140
negative regulation of gene expression GO:0010629 312 0.135
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 33 0.132
negative regulation of gene silencing GO:0060969 27 0.127
cell communication GO:0007154 345 0.120
growth GO:0040007 157 0.115
response to oxygen containing compound GO:1901700 61 0.112
cell wall biogenesis GO:0042546 93 0.105
positive regulation of biosynthetic process GO:0009891 336 0.104
positive regulation of transport GO:0051050 32 0.102
positive regulation of transcription dna templated GO:0045893 286 0.100
negative regulation of chromatin silencing at telomere GO:0031939 15 0.099
meiosis i GO:0007127 92 0.095
regulation of chromatin silencing GO:0031935 39 0.092
signaling GO:0023052 208 0.091
internal peptidyl lysine acetylation GO:0018393 52 0.088
organonitrogen compound biosynthetic process GO:1901566 314 0.087
carboxylic acid biosynthetic process GO:0046394 152 0.087
cellular protein catabolic process GO:0044257 213 0.085
lipid metabolic process GO:0006629 269 0.082
meiotic cell cycle process GO:1903046 229 0.077
alcohol metabolic process GO:0006066 112 0.074
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.073
cellular response to extracellular stimulus GO:0031668 150 0.073
regulation of transport GO:0051049 85 0.072
single organism signaling GO:0044700 208 0.071
phytosteroid metabolic process GO:0016128 31 0.069
regulation of transcription from rna polymerase i promoter GO:0006356 36 0.069
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.068
double strand break repair GO:0006302 105 0.067
cellular amino acid biosynthetic process GO:0008652 118 0.067
response to chemical GO:0042221 390 0.066
protein ubiquitination GO:0016567 118 0.065
modification dependent protein catabolic process GO:0019941 181 0.064
proteolysis GO:0006508 268 0.063
single organism catabolic process GO:0044712 619 0.062
protein acylation GO:0043543 66 0.061
regulation of response to external stimulus GO:0032101 20 0.060
response to nutrient levels GO:0031667 150 0.058
protein localization to organelle GO:0033365 337 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.057
monocarboxylic acid metabolic process GO:0032787 122 0.056
sporulation resulting in formation of a cellular spore GO:0030435 129 0.055
positive regulation of transcription from rna polymerase ii promoter in response to heat stress GO:0061408 12 0.055
regulation of localization GO:0032879 127 0.053
cellular ketone metabolic process GO:0042180 63 0.052
regulation of cellular localization GO:0060341 50 0.052
intracellular protein transport GO:0006886 319 0.051
nitrogen compound transport GO:0071705 212 0.050
cell aging GO:0007569 70 0.050
response to abiotic stimulus GO:0009628 159 0.049
chromatin silencing GO:0006342 147 0.048
Fly
cellular lipid metabolic process GO:0044255 229 0.048
carboxylic acid metabolic process GO:0019752 338 0.048
dna replication initiation GO:0006270 48 0.048
small molecule biosynthetic process GO:0044283 258 0.048
developmental process GO:0032502 261 0.047
regulation of cellular response to stress GO:0080135 50 0.046
protein modification by small protein conjugation GO:0032446 144 0.046
positive regulation of cell communication GO:0010647 28 0.044
protein transport GO:0015031 345 0.044
signal transduction GO:0007165 208 0.044
regulation of intracellular signal transduction GO:1902531 78 0.044
response to heat GO:0009408 69 0.044
positive regulation of cellular biosynthetic process GO:0031328 336 0.042
steroid biosynthetic process GO:0006694 35 0.042
mitochondrion organization GO:0007005 261 0.042
single organism cellular localization GO:1902580 375 0.042
negative regulation of cellular component organization GO:0051129 109 0.042
fatty acid metabolic process GO:0006631 51 0.041
regulation of response to extracellular stimulus GO:0032104 20 0.041
sexual sporulation GO:0034293 113 0.041
proteasomal protein catabolic process GO:0010498 141 0.040
protein catabolic process GO:0030163 221 0.040
cellular response to oxygen containing compound GO:1901701 43 0.039
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.039
cellular response to oxidative stress GO:0034599 94 0.039
response to external stimulus GO:0009605 158 0.038
response to organic substance GO:0010033 182 0.037
glycerolipid metabolic process GO:0046486 108 0.037
regulation of chromatin silencing at telomere GO:0031938 27 0.037
macromolecule catabolic process GO:0009057 383 0.037
regulation of gene silencing GO:0060968 41 0.037
alcohol biosynthetic process GO:0046165 75 0.036
positive regulation of cell death GO:0010942 3 0.035
positive regulation of nucleic acid templated transcription GO:1903508 286 0.035
cellular polysaccharide metabolic process GO:0044264 55 0.035
response to reactive oxygen species GO:0000302 22 0.035
positive regulation of catabolic process GO:0009896 135 0.035
regulation of signal transduction GO:0009966 114 0.034
organic hydroxy compound metabolic process GO:1901615 125 0.034
replicative cell aging GO:0001302 46 0.034
negative regulation of intracellular signal transduction GO:1902532 27 0.033
sporulation GO:0043934 132 0.033
cellular response to heat GO:0034605 53 0.032
regulation of protein localization GO:0032880 62 0.032
macroautophagy GO:0016236 55 0.032
chromatin silencing at telomere GO:0006348 84 0.032
positive regulation of programmed cell death GO:0043068 3 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.031
dna templated transcription elongation GO:0006354 91 0.031
cellular response to chemical stimulus GO:0070887 315 0.031
response to organic cyclic compound GO:0014070 1 0.030
death GO:0016265 30 0.030
response to extracellular stimulus GO:0009991 156 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.029
establishment of protein localization GO:0045184 367 0.029
cellular alcohol biosynthetic process GO:0044108 29 0.029
glycerophospholipid metabolic process GO:0006650 98 0.028
sterol biosynthetic process GO:0016126 35 0.028
protein modification by small protein conjugation or removal GO:0070647 172 0.028
regulation of cellular component organization GO:0051128 334 0.027
positive regulation of response to stimulus GO:0048584 37 0.027
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.027
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.027
regulation of response to nutrient levels GO:0032107 20 0.026
fungal type cell wall biogenesis GO:0009272 80 0.026
positive regulation of cellular catabolic process GO:0031331 128 0.026
carboxylic acid catabolic process GO:0046395 71 0.026
cellular response to starvation GO:0009267 90 0.025
ncrna processing GO:0034470 330 0.025
sulfur compound biosynthetic process GO:0044272 53 0.025
organic acid metabolic process GO:0006082 352 0.025
regulation of mapk cascade GO:0043408 22 0.024
regulation of cellular catabolic process GO:0031329 195 0.024
positive regulation of organelle organization GO:0010638 85 0.024
organic hydroxy compound biosynthetic process GO:1901617 81 0.024
regulation of cell communication GO:0010646 124 0.024
phospholipid metabolic process GO:0006644 125 0.024
positive regulation of phosphorus metabolic process GO:0010562 147 0.023
regulation of response to stimulus GO:0048583 157 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.023
protein import into nucleus GO:0006606 55 0.023
response to oxidative stress GO:0006979 99 0.022
regulation of signaling GO:0023051 119 0.022
lipid catabolic process GO:0016042 33 0.022
regulation of dna templated transcription in response to stress GO:0043620 51 0.022
carbohydrate derivative metabolic process GO:1901135 549 0.021
small molecule catabolic process GO:0044282 88 0.021
protein complex biogenesis GO:0070271 314 0.021
cellular amino acid metabolic process GO:0006520 225 0.021
cell development GO:0048468 107 0.021
transfer rna gene mediated silencing GO:0061587 14 0.021
regulation of intracellular protein transport GO:0033157 13 0.021
cellular response to external stimulus GO:0071496 150 0.020
positive regulation of rna metabolic process GO:0051254 294 0.020
anatomical structure development GO:0048856 160 0.020
regulation of cell cycle process GO:0010564 150 0.020
organelle localization GO:0051640 128 0.020
regulation of macroautophagy GO:0016241 15 0.020
cellular response to organic substance GO:0071310 159 0.020
double strand break repair via nonhomologous end joining GO:0006303 27 0.020
response to temperature stimulus GO:0009266 74 0.019
negative regulation of cellular response to alkaline ph by negative regulation of transcription from rna polymerase ii promoter GO:1900463 1 0.019
negative regulation of steroid biosynthetic process GO:0010894 1 0.019
gene silencing GO:0016458 151 0.019
Fly
ergosterol biosynthetic process GO:0006696 29 0.018
anatomical structure morphogenesis GO:0009653 160 0.018
negative regulation of organelle organization GO:0010639 103 0.018
ubiquitin dependent protein catabolic process GO:0006511 181 0.018
response to starvation GO:0042594 96 0.018
anatomical structure formation involved in morphogenesis GO:0048646 136 0.018
positive regulation of gene expression GO:0010628 321 0.017
amide transport GO:0042886 22 0.017
response to nutrient GO:0007584 52 0.017
transcription from rna polymerase i promoter GO:0006360 63 0.017
sterol metabolic process GO:0016125 47 0.017
negative regulation of cell cycle GO:0045786 91 0.017
positive regulation of cytoplasmic transport GO:1903651 4 0.017
protein deacetylation GO:0006476 26 0.017
positive regulation of transcription from rna polymerase ii promoter in response to ethanol GO:0061410 3 0.017
developmental process involved in reproduction GO:0003006 159 0.017
protein complex assembly GO:0006461 302 0.016
carbohydrate metabolic process GO:0005975 252 0.016
regulation of cellular ketone metabolic process GO:0010565 42 0.016
modification dependent macromolecule catabolic process GO:0043632 203 0.016
chromatin silencing at rdna GO:0000183 32 0.016
mapk cascade GO:0000165 30 0.016
positive regulation of signal transduction GO:0009967 20 0.016
positive regulation of secretion GO:0051047 2 0.015
cellular macromolecule catabolic process GO:0044265 363 0.015
regulation of transcription factor import into nucleus GO:0042990 4 0.015
regulation of autophagy GO:0010506 18 0.015
response to hydrogen peroxide GO:0042542 12 0.015
peroxisome organization GO:0007031 68 0.015
fatty acid beta oxidation GO:0006635 12 0.015
cell cycle phase transition GO:0044770 144 0.015
positive regulation of rna biosynthetic process GO:1902680 286 0.015
regulation of protein targeting GO:1903533 10 0.015
fatty acid catabolic process GO:0009062 17 0.014
negative regulation of response to salt stress GO:1901001 2 0.014
positive regulation of fatty acid beta oxidation by positive regulation of transcription from rna polymerase ii promoter GO:0097235 1 0.014
ergosterol metabolic process GO:0008204 31 0.014
aging GO:0007568 71 0.014
filamentous growth GO:0030447 124 0.014
regulation of sodium ion transport GO:0002028 1 0.013
protein import GO:0017038 122 0.013
programmed cell death GO:0012501 30 0.013
positive regulation of transcription from rna polymerase ii promoter in response to salt stress GO:0036251 4 0.013
positive regulation of transcription from rna polymerase ii promoter by oleic acid GO:0061429 4 0.013
ion homeostasis GO:0050801 118 0.013
signal transduction by phosphorylation GO:0023014 31 0.013
stress activated protein kinase signaling cascade GO:0031098 4 0.013
glycerophospholipid biosynthetic process GO:0046474 68 0.012
non recombinational repair GO:0000726 33 0.012
single organism nuclear import GO:1902593 56 0.012
cellular developmental process GO:0048869 191 0.012
cell division GO:0051301 205 0.012
cell death GO:0008219 30 0.012
response to endoplasmic reticulum stress GO:0034976 23 0.012
regulation of mitochondrion organization GO:0010821 20 0.012
regulation of potassium ion concentration by positive regulation of transcription from rna polymerase ii promoter GO:0097301 1 0.012
regulation of cell cycle phase transition GO:1901987 70 0.012
posttranscriptional regulation of gene expression GO:0010608 115 0.012
positive regulation of transcription from rna polymerase ii promoter in response to increased salt GO:0061404 4 0.012
cation transport GO:0006812 166 0.012
acetate biosynthetic process GO:0019413 4 0.012
positive regulation of secretion by cell GO:1903532 2 0.012
regulation of protein transport GO:0051223 17 0.012
mitotic cell cycle checkpoint GO:0007093 56 0.012
carbon catabolite regulation of transcription GO:0045990 39 0.012
establishment of organelle localization GO:0051656 96 0.011
negative regulation of cellular response to alkaline ph GO:1900068 1 0.011
positive regulation of transcription by oleic acid GO:0061421 4 0.011
protein dna complex assembly GO:0065004 105 0.011
chromatin remodeling GO:0006338 80 0.011
Fly
peptide metabolic process GO:0006518 28 0.011
regulation of cellular amine metabolic process GO:0033238 21 0.011
response to uv GO:0009411 4 0.011
organelle fission GO:0048285 272 0.011
filamentous growth of a population of unicellular organisms GO:0044182 109 0.011
glutathione metabolic process GO:0006749 16 0.011
positive regulation of signaling GO:0023056 20 0.011
positive regulation of sodium ion transport by positive regulation of transcription from rna polymerase ii promoter GO:0061423 1 0.011
fungal type cell wall organization or biogenesis GO:0071852 169 0.011
negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from rna polymerase ii promoter GO:1900464 2 0.011
regulation of organelle organization GO:0033043 243 0.011
cellular response to zinc ion starvation GO:0034224 3 0.011
negative regulation of carbohydrate metabolic process GO:0045912 17 0.011
positive regulation of peroxisome organization by positive regulation of transcription from rna polymerase ii promoter GO:0061424 1 0.011
regulation of protein localization to nucleus GO:1900180 16 0.011
regulation of translation GO:0006417 89 0.010
negative regulation of cellular carbohydrate metabolic process GO:0010677 17 0.010
single organism developmental process GO:0044767 258 0.010
transmembrane transport GO:0055085 349 0.010
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 34 0.010
polyol metabolic process GO:0019751 22 0.010
nuclear import GO:0051170 57 0.010
single organism reproductive process GO:0044702 159 0.010
regulation of lipid catabolic process GO:0050994 4 0.010
regulation of transcription from rna polymerase ii promoter by calcium mediated signaling GO:1900621 1 0.010
positive regulation of transcription from rna polymerase ii promoter in response to calcium ion GO:0061400 1 0.010
positive regulation of lipid catabolic process GO:0050996 4 0.010

EAF3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022
disease of anatomical entity DOID:7 0 0.019